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1. Auteurs

Author

Abdel-Baki, Amal, primary, Amado, Isabelle, additional, Arfeuillère, Sophie, additional, Arnaud, Ingrid, additional, Arthur, Maïté, additional, Babinet, Marie-Noëlle, additional, Bazin, Nadine, additional, Bellier-Teichmann, Tanja, additional, Bismuth, Corinne, additional, Blain-Pierre, Fabienne, additional, Bloch, Pascal, additional, Bogey, Alice, additional, Bonilla-Guerrero, Julien, additional, Bonsack, Charles, additional, Borrel, Béatrice, additional, Boulon, Yann, additional, Bourlier, Emmanuelle, additional, Bralet, Marie-Cécile, additional, Brana, Armando, additional, Brénugat-Herné, Lindsay, additional, Brousse, Georges, additional, Brunet, Éric, additional, Bulzacka, Eva, additional, Cady, Florian, additional, Callot, Jérémy, additional, Caria, Aude, additional, Cellard, Caroline, additional, Cervello, Sophie, additional, Chambon, Valérian, additional, Charrier, Philippe, additional, Chatelard, Fabienne, additional, Conus, Philippe, additional, Corbière, Marc, additional, Danset-Alexandre, Charlotte, additional, Deegan, Patricia, additional, Delourme, Gwenaelle, additional, Dematteis, Maurice, additional, Demily, Caroline, additional, Destaillats, Jean-Marc, additional, Duboc, Chloé, additional, Dubreucq, Julien, additional, Dubrulle, Aurélie, additional, Dupuis, Marie, additional, Durand, Bernard, additional, Ensenlaz, Xavier, additional, Faraldo, Mégane, additional, Farhat, Sarah-Lise, additional, Favre, Émilie, additional, Favrod, Jérôme, additional, Franck, Nicolas, additional, François, Guillaume, additional, Frankhauser, Adeline, additional, Fredericks, Jennifer, additional, Frobert, Laurent, additional, Fulachier, Delphine, additional, Gabayet, Franck, additional, Gaudelus, Baptiste, additional, Gautier, Corinne, additional, Gayton, Roger, additional, Giordana, Jean-Yves, additional, Baro, Élisabeth Giraud, additional, Gobbo, Julien, additional, Gozlan, Guy, additional, Greacen, Tim, additional, Gremaud, Katya, additional, Grivet, Isabelle, additional, Guy, Cyrielle, additional, Germaneau, Ghina Harika, additional, Hochard, Christophe, additional, Hodé, Yann, additional, Ismailaj, Alban, additional, Jaafari, Nematollah, additional, Jobert, Éliane, additional, Jossserand, Anne-Claire, additional, Jouet, Emmanuelle, additional, Kaliuzhna, Mariia, additional, Khazaal, Yasser, additional, Klein, Rémy, additional, Koubichkine, Alexandra, additional, Kulsa, Mila Kirstie, additional, Lagasse, Stéphanie, additional, Lama-Lama, Pablo, additional, Lambert, Thierry, additional, Lançon, Christophe, additional, Launay, Corinne, additional, Lecardeur, Laurent, additional, Le Cardinal, Patrick, additional, Lecomte, Tania, additional, Leguay, Denis, additional, Leignier, Sylvain, additional, Lindenmayer, Jean-Pierre, additional, Loubières, Céline, additional, Lucas, Thierry, additional, Maillebuau, Mathilde, additional, Malangin, Brigitte, additional, Marsili, Massimo, additional, Martin, Brice, additional, Martin, Juliette, additional, Massoubre, Catherine, additional, Maugiron, Philippe, additional, Medalia, Alice, additional, Melis, Fanny, additional, Meunier-Cussac, Sophie, additional, Morandi, Stéphane, additional, Morin, Laurent, additional, Ngakui, Anne, additional, Nguyen, Alexandra, additional, Oker, Ali, additional, Orens, Sandrine, additional, Pachoud, Bernard, additional, Passerieux, Christine, additional, Pellet, Jacques, additional, Pellet, Joanie, additional, Penn, David, additional, Pennel, Lucie, additional, Périer, Claire-Cécile, additional, Petitjean, François, additional, Peyroux, Élodie, additional, de Pierrefeu, Inès, additional, Planas, Pedro, additional, Plane, Morgane, additional, Pomini, Valentino, additional, Pousthomis, Malgorzata, additional, Prouteau, Antoinette, additional, Quilès, Clélia, additional, Raffard, Stéphane, additional, Rebelle, Sandrine, additional, Reeder, Clare, additional, Regnier, Jennifer, additional, Rengade, Charles-Édouard, additional, Revil, Katia, additional, Ridders, Jean-François, additional, Rigaut, Bérangère, additional, Rivet, Amandine, additional, R-Mercier, Alexandra, additional, Rochet, Cécile, additional, Roelandt, Jean-Luc, additional, Roussel, Céline, additional, Roux, Paul, additional, Salas-Toquero, Caroline, additional, Schoendorff, Marianne, additional, Staedel, Bérénice, additional, Thibaudeau, Élisabeth, additional, Todd, Aurélia, additional, Todoroff, Floriane, additional, Van der Henst, Jean-Baptiste, additional, Vanzetti, Marie, additional, Verdoux, Hélène, additional, Vianin, Pascal, additional, Vidon, Gilles, additional, Willard, Dominique, additional, Wykes, Til, additional, and Younès, Nadia, additional

Published
2018
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5. La remédiation cognitive avec RECOS : Guide du thérapeute pour le traitement des troubles psychiques

Author

Vianin, Pascal, Vianin, Pascal, Vianin, Pascal, and Vianin, Pascal

Abstract

Découvrez la thérapie RECOS, un outil thérapeutique innovant qui aide à la réinsersion des personnes souffrants de troubles psychiques.La remédiation cognitive est devenue, en quelques années, un outil thérapeutique essentiel pour aider les personnes souffrant de troubles psychiques et d’une altération des fonctions cognitives à se réinsérer dans leur environnement social et/ou professionnel. La thérapie RECOS est l’une des seules à proposer un entraînement qui cible des objectifs individualisés et fonctionnels, favorisant ainsi le processus du rétablissement dans son ensemble. Pascal Vianin, concepteur du programme RECOS, propose un guide pratique à destination des thérapeutes et professionnels engagés auprès de ces personnes. Il présente les postulats théoriques sur lesquels se base l’intervention du thérapeute et livre une description approfondie des outils de cette thérapie, de leur application pratique et de leurs avantages. L’ouvrage comprend de nombreux exemples concrets ainsi que des conseils de l’auteur afin de personnaliser la thérapie pour l’adapter à chaque patient. Il est un complément indispensable à la formation au programme RECOS, destiné au personnel soignant qui s’intéresse à la remédiation cognitive et à tous ceux qui sont engagés dans des processus de formation ou de réinsertion sociale et professionnelle.Le manuel incontournable pour se former à la remédiation cognitive avec la thérapie RECOS !

Published
2021

6. Specific vs general cognitive remediation for executive functioning in schizophrenia: A multicenter randomized trial

Author

Franck, Nicolas, Duboc, Chloé, Sundby, Charlotte, Amado, Isabelle, Wykes, Til, Demily, Caroline, Launay, Corinne, Le Roy, Vincent, Bloch, Pascal, Willard, Dominique, Todd, Aurélia, Petitjean, François, Foullu, Sandrine, Briant, Patrick, Grillon, Marie-Laure, Deppen, Patricia, Verdoux, Hélène, Bralet, Marie-Cécile, Januel, Dominique, Riche, Benjamin, Roy, Pascal, and Vianin, Pascal

Published
2013
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15. Liste des collaborateurs

Author

Bardy-Linder, Sabrina, primary, Bonsack, Charles, additional, Cottraux, Jean, additional, Favrod, Jérôme, additional, Giuliani, Fabienne, additional, Haour, France, additional, Jouvent, Roland, additional, Lachaux, Jean-Philippe, additional, Lallart, Élise, additional, Montefiore, Delphine, additional, Mouron, Dominique, additional, Pelissolo, Antoine, additional, Pernier, Sophie, additional, Pomini, Valentino, additional, Pull, Charles, additional, Schenk, Françoise, additional, Schoendorff, Benjamin, additional, Schwyn, Catherine, additional, Servan-Schreiber, David, additional, Servant, Dominique, additional, and Vianin, Pascal, additional

Published
2009
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22. La remédiation cognitive dans la schizophrénie : Le programme RECOS

Author

Vianin, Pascal, Vianin, Pascal, Vianin, Pascal, and Vianin, Pascal

Abstract

Des thérapies appropriées pour remédier aux psychopathologies de personnalité multiple. La remédiation cognitive est devenue en quelques années un outil thérapeutique important dans le domaine des maladies psychiatriques, et plus particulièrement dans celui des troubles schizophréniques. Parmi les programmes utilisés, RECOS est l’un des seuls à proposer un entraînement qui tient compte du profil cognitif individuel, permettant ainsi de répondre de manière ciblée à la grande hétérogénéité des déficits observés. Cet ouvrage constitue le support de base indispensable à la formation délivrée aux futurs thérapeutes RECOS. Il se divise en deux parties. La première partie présente les données scientifiques actuelles sur les troubles cognitifs de la schizophrénie et les moyens d’y remédier. Le lien entre les performances cognitives et les capacités fonctionnelles permet de comprendre comment et pourquoi la remédiation cognitive favorise la réinsertion sociale et professionnelle. La deuxième partie fait office de manuel d’utilisation pour tous les thérapeutes (psychologues, psychiatres, infirmiers, ergothérapeutes) souhaitant utiliser RECOS. L’ouvrage décrit les pathologies psychiatriques visées par le programme, la schizophrénie n’étant pas la seule concernée. Il aborde ensuite les différentes étapes du traitement, en consacrant une place importante à l’évaluation cognitive et clinique ainsi qu’aux exercices de remédiation. Des cas cliniques illustrent la manière d’adapter le travail thérapeutique au profil cognitif de chaque participant. Afin que le lecteur puisse bénéficier d’un maximum d’informations et de documents pratiques, plusieurs outils nécessaires à l’utilisation du programme figurent en annexe de l’ouvrage. Destiné aux praticiens, cet ouvrage de référence identifie les troubles cognitifs liés à la schizophrénie et propose des traitements adaptés. À PROPOS DE L'AUTEUR Pascal Vianin a développé le programme RECOS dès le début des années 2000. Il exerce actuellemen

Published
2013

24. Exploratory Investigation of a Customized cognitive remediation program for individuals living with schizophrenia

Author

Vianin, Pascal, Deppen, Patricia, Croisile, Bernard, Tarpin-Bernard, Franck, Sarrazin-Bruchez, P., Dukes, R., Grillon, M., Ingénierie de l’Interaction Homme-Machine (IIHM), Laboratoire d'Informatique de Grenoble (LIG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF), and Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[INFO.INFO-HC]Computer Science [cs]/Human-Computer Interaction [cs.HC], ComputingMilieux_MISCELLANEOUS
Abstract

International audience; no abstract

Published
2010

25. Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients

Author

Lavoie, Suzie, Murray, Micah M., Deppen, Patricia, Knyazeva, Maria G., Berk, Michael, Boulat, Olivier, Bovet, Pierre, Bush, Ashley I., Conus, Philippe, Copolov, David, Fornari, Eleonora, Meuli, Reto, Solida, Alessandra, Vianin, Pascal, Cuénod, Michel, Buclin, Thierry, Do, Kim Q., Lavoie, Suzie, Murray, Micah M., Deppen, Patricia, Knyazeva, Maria G., Berk, Michael, Boulat, Olivier, Bovet, Pierre, Bush, Ashley I., Conus, Philippe, Copolov, David, Fornari, Eleonora, Meuli, Reto, Solida, Alessandra, Vianin, Pascal, Cuénod, Michel, Buclin, Thierry, and Do, Kim Q.

Published
2008

27. Glutathione Precursor, N-Acetyl-Cysteine, Improves Mismatch Negativity in Schizophrenia Patients

Author

Lavoie, Suzie, primary, Murray, Micah M, additional, Deppen, Patricia, additional, Knyazeva, Maria G, additional, Berk, Michael, additional, Boulat, Olivier, additional, Bovet, Pierre, additional, Bush, Ashley I, additional, Conus, Philippe, additional, Copolov, David, additional, Fornari, Eleonora, additional, Meuli, Reto, additional, Solida, Alessandra, additional, Vianin, Pascal, additional, Cuénod, Michel, additional, Buclin, Thierry, additional, and Do, Kim Q, additional

Published
2007
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31. Increased activation in Broca's area after cognitive remediation in schizophrenia

Author

Vianin, Pascal, Urben, Sebastien, Magistretti, Pierre, Marquet, Pierre, Fornari, Eleonora, and Jaugey, Laure

Subjects
Executive function, Verbalization, Functional magnetic resonance imaging, Frontal area, Verbal fluency, behavioral disciplines and activities
Abstract

Functional magnetic resonance imaging (fMRI) was used to measure changes in cerebral activity in patients with schizophrenia after participation in the Cognitive Remediation Program for Schizophrenia and other related disorders (RECOS). As RECOS therapists make use of problem solving and verbal mediation techniques, known to be beneficial in the rehabilitation of dysexecutive syndromes, we expected an increased activation of frontal areas after remedial:ion. Executive functioning and cerebral activation during a covert verbal fluency task were measured in eight patients with schizophrenia before (T1) and after (T2) 14 weeks of RECOS therapy. The same measures were recorded in eight patients with schizophrenia who did not participate in RECOS at the same intervals of time (TAU group). Increased activation in Broca's area, as well as improvements in performance of executive/frontal tasks, was observed after cognitive training. Metacognitive techniques of verbalization are hypothesized to be the main factor underlying the brain changes observed in the present study. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

32. Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients.

Author

Lavoie S, Murray MM, Deppen P, Knyazeva MG, Berk M, Boulat O, Bovet P, Bush AI, Conus P, Copolov D, Fornari E, Meuli R, Solida A, Vianin P, Cuénod M, Buclin T, and Do KQ

Subjects
Acetylcysteine therapeutic use, Acoustic Stimulation methods, Adult, Brain Mapping, Cerebral Cortex drug effects, Cerebral Cortex physiopathology, Cross-Over Studies, Discrimination, Psychological drug effects, Double-Blind Method, Electroencephalography, Female, Free Radical Scavengers therapeutic use, Glutathione blood, Humans, Male, Middle Aged, Neuropsychological Tests, Reaction Time drug effects, Retrospective Studies, Schizophrenia blood, Schizophrenia drug therapy, Schizophrenia pathology, Time Factors, Acetylcysteine pharmacology, Contingent Negative Variation drug effects, Evoked Potentials, Auditory drug effects, Free Radical Scavengers pharmacology, Schizophrenia physiopathology
Abstract

In schizophrenia patients, glutathione dysregulation at the gene, protein and functional levels, leads to N-methyl-D-aspartate (NMDA) receptor hypofunction. These patients also exhibit deficits in auditory sensory processing that manifests as impaired mismatch negativity (MMN), which is an auditory evoked potential (AEP) component related to NMDA receptor function. N-acetyl-cysteine (NAC), a glutathione precursor, was administered to patients to determine whether increased levels of brain glutathione would improve MMN and by extension NMDA function. A randomized, double-blind, cross-over protocol was conducted, entailing the administration of NAC (2 g/day) for 60 days and then placebo for another 60 days (or vice versa). 128-channel AEPs were recorded during a frequency oddball discrimination task at protocol onset, at the point of cross-over, and at the end of the study. At the onset of the protocol, the MMN of patients was significantly impaired compared to sex- and age- matched healthy controls (p=0.003), without any evidence of concomitant P300 component deficits. Treatment with NAC significantly improved MMN generation compared with placebo (p=0.025) without any measurable effects on the P300 component. MMN improvement was observed in the absence of robust changes in assessments of clinical severity, though the latter was observed in a larger and more prolonged clinical study. This pattern suggests that MMN enhancement may precede changes to indices of clinical severity, highlighting the possible utility AEPs as a biomarker of treatment efficacy. The improvement of this functional marker may indicate an important pathway towards new therapeutic strategies that target glutathione dysregulation in schizophrenia.

Published
2008
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33. [Cognitive remediation: a new approach for treating schizophrenia].

Author

Vianin P

Subjects
Cognition Disorders etiology, Humans, Schizophrenia complications, Treatment Outcome, Cognitive Behavioral Therapy, Schizophrenia therapy
Abstract

Two years ago, the "E. Minkowski" section of the "Département Universitaire de Psychiatrie Adulte" in Lausanne (DUPA) developed a cognitive remediation program for young schizophrenic patients. Preliminary results indicate a significant improvement in cognitive performance in most patients. Despite encouraging results, cognitive remediation therapies for patients with schizophrenia are rarely used in our country. The importance of cognitive deficits contrasts with the lack of resources engaged for their remediation. Some hypotheses are discussed for understanding why the treatment of cognitive deficits in schizophrenia has been delayed.

Published
2004

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