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3. State of the Art for Refractory Cough: Multidisciplinary Approach

Author

Anne E. Vertigan

Subjects
speech pathology, nonpharmaceutical, chronic cough, inducible laryngeal obstruction, vocal cord dysfunction, Diseases of the respiratory system, RC705-779
Abstract

Chronic cough is a common problem that can be refractory to medical treatment. Nonpharmaceutical management of chronic cough has an important role in well selected patients. This review article outlines the history of chronic cough management, current approaches to speech pathology management of the condition and new modalities of nonpharmaceutical treatment. There is a need for further research into nonpharmaceutical options with well described randomised control trials.

Published
2023
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5. Building capacity for climate adaptation planning in protected area management: Options and challenges for World Heritage

Author

Melbourne-Thomas, Jess, Lin, Brenda B., Hopkins, Mandy, Hill, Rosemary, Dunlop, Michael, MacGregor, Nicholas, Merson, Samuel D., Vertigan, Caitlin, Donegan, Luke, Sheppard, Marian, Meyers, Jacqui, Thomas, Linda, Visschers, Lola, McNeair, Bianca, Syme, Lance, Grant, Chrissy, Pedrocchi, Nicholas, Oakley, Patricia, Stevens, Amy, Rose, Denis, Rose, Erin, Gould, Jade, Locke, John, Maybanks, Lynda, and Ireland, Tracy

Published
2024
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8. Impact of Landscape Fire Smoke Exposure on Patients With Asthma With or Without Laryngeal Hypersensitivity

Author

Vertigan, Anne E., Harvey, Erin S., Beyene, Tesfalidet, Van Buskirk, Joseph, Holliday, Elizabeth G., Bone, Sarah L., McDonald, Vanessa M., Horvat, Jay C., Murphy, Vanessa E., Jensen, Megan E., Morgan, Geoffrey G., Zosky, Graeme R., Peters, Matthew, Farah, Claude S., Jenkins, Christine R., Katelaris, Constance H., Harrington, John, Langton, David, Bardin, Philip, Katsoulotos, Gregory P., Upham, John W., Chien, Jimmy, Bowden, Jeffrey J., Rimmer, Janet, Bell, Rose, and Gibson, Peter G.

Published
2023
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10. Interaction effect of chronic cough and ageing on increased risk of exacerbation in patients with asthma: a prospective cohort study in a real-world setting

Author

Fan Ding Jin, Ji Wang, Su Jun Deng, Woo-Jung Song, Xin Zhang, Chang Yong Wang, Si Yang Gao, Kian Fan Chung, Ye Yang, Anne E. Vertigan, Feng Ming Luo, Surinder S. Birring, Wei Min Li, Dan Liu, and Gang Wang

Subjects
Medicine
Abstract

Background Older adults with asthma have the greatest burden and worst outcomes, and there is increasing evidence that chronic cough (CC) is associated with asthma severity and poor prognosis. However, the clinical characteristics of older adult patients with both asthma and CC remain largely unknown. Methods Participants with stable asthma underwent two cough assessments within 3 months to define the presence of CC. Patients were divided into four groups based on CC and age (cut-off ≥60 years). Multidimensional assessment was performed at baseline, followed by a 12-month follow-up to investigate asthma exacerbations. Logistic regression models were used to explore the interaction effect of CC and age on asthma control and exacerbations. Results In total, 310 adult patients were prospectively recruited and divided into four groups: older CC group (n=46), older non-CC group (n=20), younger CC group (n=112) and younger non-CC group (n=132). Compared with the younger non-CC group, the older CC group had worse asthma control and quality of life and increased airflow obstruction. The older CC group showed an increase in moderate-to-severe exacerbations during the 12-month follow-up. There was a significant interaction effect of CC and ageing on the increased moderate-to-severe exacerbations (adjusted risk ratio 2.36, 95% CI 1.47–3.30). Conclusion Older asthma patients with CC have worse clinical outcomes, including worse asthma control and quality of life, increased airway obstruction and more frequent moderate-to-severe exacerbations, which can be partly explained by the interaction between CC and ageing.

Published
2023
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11. The impact of the 2019/2020 Australian landscape fires on infant feeding and contaminants in breast milk in women with asthma

Author

Tesfalidet Beyene, Graeme R. Zosky, Peter G. Gibson, Vanessa M. McDonald, Elizabeth G. Holliday, Jay C. Horvat, Anne E. Vertigan, Joe Van Buskirk, Geoffrey G. Morgan, Edward Jegasothy, Ivan Hanigan, Vanessa E. Murphy, and Megan E. Jensen

Subjects
Breast milk, Infant feeding, Environmental contaminants, Landscape fire, Bushfire, Smoke, Pediatrics, RJ1-570, Public aspects of medicine, RA1-1270
Abstract

Abstract Background The 2019/2020 Australian landscape fires (bushfires) resulted in prolonged extreme air pollution; little is known about the effects on breastfeeding women and their infants. This study aimed to examine the impact of prolonged landscape fires on infant feeding methods and assess the concentration of polycyclic aromatic hydrocarbons (PAHs) and elements in breast milk samples. Methods From May – December 2020, women with asthma, who were feeding their infants during the fires, were recruited from an existing cohort. Data on infant feeding and maternal concern during the fires were retrospectively collected. Breast milk samples were collected from a sample of women during the fire period and compared with samples collected outside of the fire period for levels of 16 PAHs (gas chromatography coupled with mass spectrometry), and 20 elements (inductively coupled plasma-mass spectrometry). Results One-hundred-and-two women who were feeding infants completed the survey, and 77 provided 92 breast milk samples. Two women reported concern about the impact of fire events on their infant feeding method, while four reported the events influenced their decision. PAHs were detected in 34% of samples collected during, versus no samples collected outside, the fire period (cross-sectional analysis); specifically, fluoranthene (median concentration 0.015 mg/kg) and pyrene (median concentration 0.008 mg/kg) were detected. Women whose samples contained fluoranthene and pyrene were exposed to higher levels of fire-related fine particulate matter and more fire days, versus women whose samples had no detectable fluoranthene and pyrene. Calcium, potassium, magnesium, sodium, sulphur, and copper were detected in all samples. No samples contained chromium, lead, nickel, barium, or aluminium. No statistically significant difference was observed in the concentration of elements between samples collected during the fire period versus outside the fire period. Conclusions Few women had concerns about the impact of fire events on infant feeding. Detection of fluoranthene and pyrene in breast milk samples was more likely during the 2019/2020 Australian fire period; however, levels detected were much lower than levels expected to be related to adverse health outcomes.

Published
2023
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13. The impact of prolonged landscape fire smoke exposure on women with asthma in Australia

Author

Tesfalidet Beyene, Vanessa E. Murphy, Peter G. Gibson, Vanessa M. McDonald, Joe Van Buskirk, Elizabeth G. Holliday, Anne E. Vertigan, Jay C. Horvat, Graeme R. Zosky, Geoffrey G. Morgan, Edward Jegasothy, Ivan Hanigan, Joerg Mattes, Adam M. Collison, and Megan E. Jensen

Subjects
Asthma, Australia, Landscape fire, Bushfire, Pregnant and/or breastfeeding women, Mental health, Gynecology and obstetrics, RG1-991
Abstract

Abstract Background Little is known about the physical and mental health impact of exposure to landscape fire smoke in women with asthma. This study examined the health impacts and information-seeking behaviours of women with asthma exposed to the 2019/2020 Australian fires, including women who were pregnant. Methods Women with asthma were recruited from the Breathing for Life Trial in Australia. Following the landscape fire exposure period, self-reported data were collected regarding symptoms (respiratory and non-respiratory), asthma exacerbations, wellbeing, quality of life, information seeking, and landscape fire smoke exposure mitigation strategies. Participants’ primary residential location and fixed site monitoring was used to geolocate and estimate exposure to landscape fire-related fine Particulate Matter (PM2.5). Results The survey was completed by 81 pregnant, 70 breastfeeding and 232 non-pregnant and non-breastfeeding women with asthma. Participants had a median daily average of 17 μg/m3 PM2.5 and 105 μg/m3 peak PM2.5 exposure over the fire period (October 2019 to February 2020). Over 80% of participants reported non-respiratory and respiratory symptoms during the fire period and 41% reported persistent symptoms. Over 82% reported asthma symptoms and exacerbations of asthma during the fire period. Half the participants sought advice from a health professional for their symptoms. Most (97%) kept windows/doors shut when inside and 94% stayed indoors to minimise exposure to landscape fire smoke. Over two in five (43%) participants reported that their capacity to participate in usual activities was reduced due to prolonged smoke exposure during the fire period. Participants reported greater anxiety during the fire period than after the fire period (mean (SD) = 53(13) versus 39 (13); p

Published
2022
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14. Myofunctional device use in oral care and swallowing: a protocol for a feasibility study in an aged care population

Author

Hollie-Ann L. Shortland, Sally Hewat, Gwendalyn Webb, and Anne E. Vertigan

Subjects
Speech-language pathology treatment, Myofunctional device, Oral hygiene, Dysphagia, Medicine (General), R5-920
Abstract

Abstract Background Poor oral health is a known predictor of aspiration pneumonia in vulnerable populations such as the elderly and chronically ill and has been linked to systemic disease, morbidity, and mortality. Reduced oral health not only places individuals at a greater risk of aspiration pneumonia but may result in pain or poorer dentition which can impact on mastication and swallowing. Consequences of this may include reduced oral intake, malnutrition, poorer health outcomes, and reduced quality of life. Few evidence-based protocols exist to manage oral care in aged care populations, and maintenance of good oral hygiene is difficult for nursing and care staff to facilitate. However, a recent literature review found that improvements in oral hygiene, oral behaviors, and swallowing, along with breathing and speech have been found to be associated with the use of myofunctional devices due to positive changes in orofacial functions such as lip seal, mastication, swallowing, and nasal breathing patterns. The primary aim of this study is to assess the feasibility of using a myofunctional device to improve oral care and swallowing function in an aged care population. Methods/design This project is a feasibility study that involves a 5-week intervention for oral hygiene and dysphagia for residents >65 years old in an aged care setting. Feasibility will be determined by the acceptability of the intervention, study recruitment and retention, and adherence to the intervention. Feasibility testing will also include an evaluation of clinical outcome measures, and sensitivity to detect changes in oral health and swallowing in an aged care population. Discussion The results of this trial will provide important information regarding the feasibility of utilizing a myofunctional device to improve oral care and dysphagia in elderly patients in an aged care facility. This knowledge will further guide and inform design of a larger trial or future research. Trial registration This trial was registered August 10, 2021, with the Australian New Zealand Clinical Trials Registry and allocated the ACTRN: ACTRN12621001359820.

Published
2022
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15. Perceptions of co-design, co-development and co-delivery (Co-3D) as part of the co-production process – Insights for climate services

Author

A. Fleming, E. Bohensky, L.X.C. Dutra, B.B. Lin, J. Melbourne-Thomas, T. Moore, S. Stone-Jovicich, C. Tozer, J.M. Clarke, L. Donegan, M. Hopkins, S. Merson, T. Remenyi, A. Swirepik, and C. Vertigan

Subjects
Co-design, Co-production, Collaboration, Australia, Case study, Participatory research, Meteorology. Climatology, QC851-999, Social sciences (General), H1-99
Abstract

Co-design, co-development, and co-delivery (Co-3D for short) are activities within the co-production research pathway that are increasingly being used in climate change science and adaptation projects. However, the research community is still coming to understand how best to incorporate Co-3D in practice, as each project has a specific context around stakeholder relationships, governance arrangements, and capacity to actively participate. This paper outlines five case studies from Australia as examples of different projects engaging with Co-3D in different ways in order to explore how Co-3D is being used and might be improved. Crucially, we include the perceptions and experiences of researchers, funders and end users, as well as our own critical reflections. Each of the projects self-describes as using ‘co-production’, but the extent and format varies widely with different combinations of co-design, co-development and/or co-delivery used in each. Our findings show that without clear understanding of Co-3D within the co-production process, aspects of Co-3D may not be properly considered in planning or implementation. Co-3D activities are not completely distinct, rather they form a continuum of engagement and integration across phases of project work. Thus, the specific definitions and delineations between these terms may not be required for them to be applied. However, practical and explicit negotiation of what ‘co-production’ means in different project contexts is needed so that all parties understand their roles and responsibilities. Further, more evaluations of outcomes and stakeholder experiences are required. We provide seven principles of Co-3D that should be considered when embarking on co-production projects.

Published
2023
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22. Global Physiology and Pathophysiology of Cough: Part 2. Demographic and Clinical Considerations: CHEST Expert Panel Report

Author

Altman, Kenneth W., Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Braman, Sidney S., Brightling, Christopher, Chang, Anne B., Coté, Andréanne, Gibson, Peter, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lane, Andrew P., Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Oppenheimer, John, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., Rubin, Bruce K., Ebihara, Satoru, Hegland, Karen, Rivet, Alycia, Gibson, Peter G., and Mazzone, Stuart B.

Published
2021
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24. Global Physiology and Pathophysiology of Cough: Part 1: Cough Phenomenology – CHEST Guideline and Expert Panel Report

Author

Abu Dabrh, AbdMoain, Altman, Kenneth W., Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Brightling, Christopher, Chang, Anne B., Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, AdamT., Irwin, Richard S., Iyer, Vivek, Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, AndrewP., Lim, Kaiser, Madison, J. Mark, Malesker, MarkA., McGarvey, Lorcan, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Oppenheimer, John, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., Lee, Kai K., Davenport, Paul W., Smith, Jaclyn A., and Mazzone, Stuart B.

Published
2021
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27. Life-Threatening and Non-Life-Threatening Complications Associated With Coughing: A Scoping Review

Author

Abu Dabrh, Abd Moain, Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Canning, Brendan, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Iyer, Vivek, Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Moore, Abigail, Murad, M. Hassan, Newcombe, Peter, Oppenheimer, John, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Tarlo, Susan M., Vertigan, Anne E., Dudiki, Natasha, and French, Cynthia L.

Published
2020
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28. Chronic Cough Due to Stable Chronic Bronchitis: CHEST Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lilly, Craig, Lim, Kaiser, Lown, Mark, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molassoitis, Alex, Murad, M. Hassan, Narasimhan, Mangala, Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., and Ireland, Belinda

Published
2020
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31. Managing Chronic Cough as a Symptom in Children and Management Algorithms: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Blackhall, Fiona, Birring, Surinder S., Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lilly, Craig, Lim, Kaiser, Lown, Mark, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Murad, M. Hassan, Narasimhan, Mangala, Oppenheimer, John, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., and Oppenheimer, John J.

Published
2020
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32. Managing Chronic Cough Due to Asthma and NAEB in Adults and Adolescents: CHEST Guideline and Expert Panel Report

Author

Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Blackhall, Fiona, Bolser, Donald C., Birring, Surinder S., Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Gibson, Peter, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Lai, Kefang, Lane, Andrew P., Lilly, Craig, Lown, Mark, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Moore, Abigail, Murad, M. Hassan, Narasimhan, Mangala, Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., Weinberger, Miles, Côté, Andreanne, Boulet, Louis-Philippe, Gibson, Peter G., and Brightling, Christopher E.

Published
2020
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33. Acute Cough Due to Acute Bronchitis in Immunocompetent Adult Outpatients: CHEST Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Blackhall, Fiona, Birring, Surinder S., Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Lai, Kefang, Lilly, Craig, Lown, Mark, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., Weinberger, Miles, Ireland, Belinda, and Linder, Jeffrey A.

Published
2020
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34. Misconceptions on behavioral cough suppression therapy for pediatric nonspecific cough: A response to Weinberger and Buettner's commentary on Fujiki et al.

Author

Slovarp, Laurie, primary, Jette, Marie, additional, Reynolds, Jane, additional, Gillespie, Amanda I, additional, Barkmeier‐Kraemer, Julie, additional, Sandage, Mary, additional, Smith, Jaclyn, additional, Haines, Jemma, additional, Vertigan, Anne, additional, and Mazzone, Stuart, additional

Published
2024
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37. Diagnosis of vocal cord dysfunction / inducible laryngeal obstruction-A Delphi study protocol.

Author

Paul Leong, Anne E Vertigan, Mark Hew, Malcolm Baxter, Debra Phyland, James H Hull, Thomas L Carroll, Peter G Gibson, Vanessa M McDonald, and Philip G Bardin

Subjects
Medicine, Science
Abstract

IntroductionCurrently there is no consistent and widely accepted approach to the diagnosis of vocal cord dysfunction/inducible laryngeal obstruction (VCD/ILO). Harmonised diagnostic methods are vital to enable optimal diagnosis, advance management and enable research. We aim to obtain consensus on how expert clinicians recognise and diagnose VCD/ILO.Methods and analysisTwo-round modified Delphi, with workshop validation.Ethics and disseminationInstitutional Board Review was obtained from the Monash Health Human Research Ethics Committee. The dissemination plan is for presentation and publication.Registration detailsRegistered at Australia and New Zealand Clinical Trials Registry ACTRN12621001520820p.

Published
2022
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38. Sled dogs as a model for PM2.5 exposure from wildfires in Alaska

Author

Jacob J. Witkop, Theresa Vertigan, Arleigh Reynolds, Lawrence Duffy, Bahareh Barati, Scott Jerome, and Kriya Dunlap

Subjects
Arctic, Wildfires, Air quality, Oxidative stress, Superoxide dismutase, Canine, Environmental sciences, GE1-350
Abstract

Particulate matter 2.5 (PM2.5) exposure induces oxidative stress associated with many negative health outcomes such as respiratory disorders, cardiovascular disease and neurodegenerative disease. Research shows that diet and exercise can improve antioxidant defense against oxidative stress. This study is the first to use an Arctic animal model to investigate the cumulative effects of two lifestyle interventions on the antioxidant response before, during, and after ambient PM 2.5 exposure from wildfire: antioxidant supplementation (Arthrospira platensis) and exercise. In a two-factorial, longitudinal design, this study divided sled dogs (n = 48) into four groups (exercise and supplemented, exercise, supplemented, and control) to (1) test the effects of a 30-day exercise and antioxidant supplementation protocol on antioxidant response; and (2) measure the antioxidant response of all groups during and after a natural wildfire event. Commercial assays for total antioxidant power (TAP) and the enzymatic antioxidant superoxide dismutase (SOD) were used as markers for antioxidant status and response. During the forest fire, SOD was increased 5- to 10-fold over pre/post-exposure levels in all groups suggesting an endogenous upregulation of defense systems in response to the acute environmental stress. TAP was lower in all groups at peak PM2.5 exposure compared to 48 h after peak exposure in all groups except the exercise alone group which may indicate that exercise offers improved endogenous defense.

Published
2021
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39. Feasibility and clinical utility of ambulatory cough monitoring in an outpatient clinical setting: a real-world retrospective evaluation

Author

Anne E. Vertigan, Sarah L. Kapela, Surinder S. Birring, and Peter G. Gibson

Subjects
Medicine
Abstract

Research question Objective quantification of cough is rarely utilised outside of research settings and the role of cough frequency monitoring in clinical practice has not been established. This study examined the clinical utility of cough frequency monitoring in an outpatient clinical setting. Methods The study involved a retrospective review of cough monitor data. Participants included 174 patients referred for treatment of cough and upper airway symptoms (103 chronic cough; 50 inducible laryngeal obstruction; 21 severe asthma) and 15 controls. Measures, taken prior to treatment, included 24-h ambulatory cough frequency using the Leicester Cough Monitor, the Leicester Cough Questionnaire and Laryngeal Hypersensitivity Questionnaire. Post-treatment data were available for 50 participants. Feasibility and clinical utility were also reported. Results Analysis time per recording was up to 10 min. 75% of participants could use the monitors correctly, and most (93%) recordings were interpretable. The geometric mean cough frequency in patients was 10.1±2.9 (mean±sd) compared to 2.4±2.0 for healthy controls (p=0.003). There was no significant difference in cough frequency between clinical groups (p=0.080). Cough frequency decreased significantly following treatment (p

Published
2021
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42. Chronic Cough and Gastroesophageal Reflux in Children: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Bolser, Donald C., Birring, Surinder S., Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Gibson, Peter, Harding, Susan M., Gold, Philip, Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Lai, Kefang, Lim, Kaiser, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Metlay, Joshua P., Molasoitis, Alex, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Turmel, Julie, Vertigan, Anne E., Weinberger, Miles, Oppenheimer, John J., Kantar, Ahmad, and Rubin, Bruce K.

Published
2019
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43. Clinically Diagnosing Pertussis-associated Cough in Adults and Children: CHEST Guideline and Expert Panel Report

Author

Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Bolser, Donald C., Birring, Surinder S., Blackwell, Fiona, Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Gibson, Peter, Gold, Philip, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Lown, Mark, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Moore, Abigail, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., Weinberger, Miles, Grant, Cameron C., and Patel, Sheena

Published
2019
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44. Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Moore, Abigail, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Turmel, Julie, Vertigan, Anne E., Wang, Gang, Weinberger, Miles, Gold, Philip M., Metlay, Joshua P., and Ireland, Belinda

Published
2019
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45. Occupational and Environmental Contributions to Chronic Cough in Adults: Chest Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Feinstein, Anthony, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Gould, Michael K., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasiotis, Alex, Murad, M. Hassan, Oppenheimer, John, Prezant, David, Restrepo, Marcos I., Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Tarlo, Susan M., Vertigan, Anne E., Wang, Gang, Weinberger, Miles, Weir, Kelly, and Vertigan, Anne

Published
2016
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46. Large Non-Planar Graphs and an Application to Crossing-Critical Graphs

Author

Ding, Guoli, Oporowski, Bogdan, Thomas, Robin, and Vertigan, Dirk

Subjects
Mathematics - Combinatorics, 05C99, 05C10, 05D10
Abstract

We prove that, for every positive integer k, there is an integer N such that every 4-connected non-planar graph with at least N vertices has a minor isomorphic to K_{4,k}, the graph obtained from a cycle of length 2k+1 by adding an edge joining every pair of vertices at distance exactly k, or the graph obtained from a cycle of length k by adding two vertices adjacent to each other and to every vertex on the cycle. We also prove a version of this for subdivisions rather than minors, and relax the connectivity to allow 3-cuts with one side planar and of bounded size. We deduce that for every integer k there are only finitely many 3-connected 2-crossing-critical graphs with no subdivision isomorphic to the graph obtained from a cycle of length 2k by joining all pairs of diagonally opposite vertices., Comment: To appear in Journal of Combinatorial Theory B. 20 pages. No figures. TeX

Published
2009

48. Cough in Children and Adults: Diagnosis, Assessment and Management (CICADA). Summary of an updated position statement on chronic cough in Australia

Author

Marchant, Julie M, primary, Chang, Anne B, additional, Kennedy, Emma, additional, King, David, additional, Perret, Jennifer L, additional, Schultz, Andre, additional, Toombs, Maree R, additional, Versteegh, Lesley, additional, Dharmage, Shyamali C, additional, Dingle, Rebecca, additional, Fitzerlakey, Naomi, additional, George, Johnson, additional, Holland, Anne, additional, Rigby, Debbie, additional, Mann, Jennifer, additional, Mazzone, Stuart, additional, O'Brien, Mearon, additional, O'Grady, Kerry‐Ann, additional, Petsky, Helen L, additional, Pham, Jonathan, additional, Smith, Sheree MS, additional, Wurzel, Danielle F, additional, Vertigan, Anne E, additional, and Wark, Peter, additional

Published
2023
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