Author: "Versaci, F" - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"Versaci, F"' showing total 375 results

Start Over Author "Versaci, F"

375 results on '"Versaci, F"'

1. Italian Society of Interventional Cardiology (GISE) and Italian Society of Arterial Hypertension (SIIA) Position Paper on the role of renal denervation in the management of the difficult-to-treat hypertension

Author: Stabile, E, Muiesan, M, Ribichini, F, Sangiorgi, G, Taddei, S, Versaci, F, Villari, B, Bacca, A, Benedetto, D, Fioretti, V, Laurenzano, E, Scapaticci, M, Saia, F, Tarantini, G, Grassi, G, Esposito, G, Muiesan, ML, Ribichini, FL, Stabile, E, Muiesan, M, Ribichini, F, Sangiorgi, G, Taddei, S, Versaci, F, Villari, B, Bacca, A, Benedetto, D, Fioretti, V, Laurenzano, E, Scapaticci, M, Saia, F, Tarantini, G, Grassi, G, Esposito, G, Muiesan, ML, and Ribichini, FL
Abstract: Renal denervation (RDN) is a safe and effective strategy for the treatment of difficult to treat hypertension. The blood pressure (BP)-lowering efficacy of RDN is comparable to those of many single antihypertensive medications and it allows to consider the RDN as a valuable option for the treatment of difficult to treat hypertension together with lifestyle modifications and medical therapy. A multidisciplinary team is of pivotal importance from the selection of the patient candidate for the procedure to the post-procedural management. Further studies are needed to investigate the effect of RDN on clinical outcomes and to better identify the predictors of BP response to RDN in order to recognize the patients who are more likely to benefit from the procedure.
Published: 2024

2. Centration assessment of an extended depth of focus contact lens for myopic progression control

Author: Rizzo, G, Di Vizio, A, Versaci, F, Przekoracka, K, Tavazzi, S, Zeri, F, Rizzo G. C., Di Vizio A., Versaci F., Przekoracka K., Tavazzi S., Zeri F., Rizzo, G, Di Vizio, A, Versaci, F, Przekoracka, K, Tavazzi, S, Zeri, F, Rizzo G. C., Di Vizio A., Versaci F., Przekoracka K., Tavazzi S., and Zeri F.
Abstract: Purpose: To evaluate the accuracy and the inter and intra-observer reliability of the centration assessment of extended depth of focus (EDOF) contact lenses (CL) using corneal topography. Method: EDOF soft CLs (Mylo, Mark'Ennovy) were fitted on thirty-three myopic students (25 females), aged 19–28 years (22.7 ± 2.0 years). For any EDOF CL, a topography over the CL and a slit lamp (SL) digital picture were taken in random order. For the topographic images, the position of the EDOF CL centre, with respect to the pupil centre, was detected by two different practitioners (one newly graduated and one with more than 20 years of clinical experience respectively) and repeated after 15 days. This measurement was compared to the one taken through the SL, considered as the gold standard, and assessed using the instrument software. Results: EDOF CLs resulted decentred inferiorly and temporally ranging, in the case of slit lamp assessment, between −0.27 ± 0.19 and 0.22 ± 0.23 mm horizontally and between −0.12 ± 0.31 and −0.17 ± 0.34 mm vertically, for the right and left eye respectively. The accuracy of the topographic assessment in determining EDOF CL centration was found to be very good compared to the SL assessment. No differences were found for the left eye, whereas in the right eye, a less temporally decentred position of the CL was detected by the topographical method (p < 0.05). However, this difference appeared clinically negligible (0.14 ± 0.22 mm). Inter-observer reliability (the differences between the two practitioners in assessing the EDOF centre) resulted significant only for the vertical coordinates of the centre position (p < 0.05). Concerning intra-observer reliability, better coefficient of precision and reliability between measurements within the same session were achieved by the more experienced practitioner, as well as a better level of the intraclass correlation coefficient in test–retest. Conclusion: The centration of the EDOF CL investigated in this
Published: 2023

3. Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry.

Author: Luca, G. De, Manzo-Silberman, S., Algowhary, M., Uguz, B., Oliveira, D.C., Ganyukov, V., Busljetik, O., Cercek, M., Okkels, L., Loh, P.H., Calmac, L., Ferrer, G.R.I., Quadros, A., Milewski, M., otto di Uccio, F. Sc, Birgelen, C. von, Versaci, F., Berg, J ., Casella, G., Wong Sung Lung, A., Kala, P., Díez Gil, J.L., Carrillo, X., Dirksen, M., Becerra, V., Lee, M.K., Juzar, D.A., Moura Joaquim, R. de, Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A., Galasso, G., Arpad, L., Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A.H., Ugur Mert, K., Flores Rios, X., Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Martínez-Luengas, I.L., Boccalatte, M., Ojeda, F.B., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H.L., Forés, J.S., Vignali, L., Pereira, H., Ordoñez, S., Arat Özkan, A., Scheller, B., Lehtola, H., Teles, R., Mantis, C., Antti, Y., Brum Silveira, J.A., Zoni, C.R., Bessonov, I., Uccello, G., Kochiadakis, G., Alexopulos, D., Uribe, C.E., Kanakakis, J., Faurie, B., Gabrielli, G., Barrios, A.G., Bachini, J.P., Rocha, A., Tam, F.C., Rodriguez, A., Lukito, A.A., Saint-Joy, V., Pessah, G., Tuccillo, A., Ielasi, A., Cortese, G., Parodi, G., Bouraghda, M.A., Moura, M., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., Verdoia, M., Luca, G. De, Manzo-Silberman, S., Algowhary, M., Uguz, B., Oliveira, D.C., Ganyukov, V., Busljetik, O., Cercek, M., Okkels, L., Loh, P.H., Calmac, L., Ferrer, G.R.I., Quadros, A., Milewski, M., otto di Uccio, F. Sc, Birgelen, C. von, Versaci, F., Berg, J ., Casella, G., Wong Sung Lung, A., Kala, P., Díez Gil, J.L., Carrillo, X., Dirksen, M., Becerra, V., Lee, M.K., Juzar, D.A., Moura Joaquim, R. de, Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A., Galasso, G., Arpad, L., Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A.H., Ugur Mert, K., Flores Rios, X., Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Martínez-Luengas, I.L., Boccalatte, M., Ojeda, F.B., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H.L., Forés, J.S., Vignali, L., Pereira, H., Ordoñez, S., Arat Özkan, A., Scheller, B., Lehtola, H., Teles, R., Mantis, C., Antti, Y., Brum Silveira, J.A., Zoni, C.R., Bessonov, I., Uccello, G., Kochiadakis, G., Alexopulos, D., Uribe, C.E., Kanakakis, J., Faurie, B., Gabrielli, G., Barrios, A.G., Bachini, J.P., Rocha, A., Tam, F.C., Rodriguez, A., Lukito, A.A., Saint-Joy, V., Pessah, G., Tuccillo, A., Ielasi, A., Cortese, G., Parodi, G., Bouraghda, M.A., Moura, M., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., and Verdoia, M.
Abstract: Item does not contain fulltext, BACKGROUND: Several reports have demonstrated the impact of the COVID-19 pandemic on the management and outcome of patients with ST-segment elevation myocardial infarction (STEMI). The aim of the current analysis is to investigate the potential gender difference in the effects of the COVID-19 pandemic on mechanical reperfusion and 30-day mortality for STEMI patients within the ISACS-STEMI COVID-19 Registry. METHODS: This retrospective multicenter registry was performed in high-volume primary percutaneous coronary intervention (PPCI) centers on four continents and included STEMI patients undergoing PPCIs in March-June 2019 and 2020. Patients were divided according to gender. The main outcomes were the incidence and timing of the PPCI, (ischemia time ≥ 12 h and door-to-balloon ≥ 30 min) and in-hospital or 30-day mortality. RESULTS: We included 16683 STEMI patients undergoing PPCIs in 109 centers. In 2020 during the pandemic, there was a significant reduction in PPCIs compared to 2019 (IRR 0.843 (95% CI: 0.825-0.861, p < 0.0001). We did not find a significant gender difference in the effects of the COVID-19 pandemic on the numbers of STEMI patients, which were similarly reduced from 2019 to 2020 in both groups, or in the mortality rates. Compared to prepandemia, 30-day mortality was significantly higher during the pandemic period among female (12.1% vs. 8.7%; adjusted HR [95% CI] = 1.66 [1.31-2.11], p < 0.001) but not male patients (5.8% vs. 6.7%; adjusted HR [95% CI] = 1.14 [0.96-1.34], p = 0.12). CONCLUSIONS: The COVID-19 pandemic had a significant impact on the treatment of patients with STEMI, with a 16% reduction in PPCI procedures similarly observed in both genders. Furthermore, we observed significantly increased in-hospital and 30-day mortality rates during the pandemic only among females. Trial registration number: NCT 04412655.
Published: 2023

4. Age-Related Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry.

Author: Luca, G. De, Algowhary, M., Uguz, B., Oliveira, D.C., Ganyukov, V., Busljetik, O., Cercek, M., Jensen, L.O., Loh, P.H., Calmac, L., Ferrer, G.R.I., Quadros, A., Milewski, M., Scotto D'Uccio, F., Birgelen, C. von, Versaci, F., Berg, J ., Casella, G., Wong Sung Lung, A., Kala, P., Díez Gil, J.L., Carrillo, X., Dirksen, M., Becerra Munoz, V., Lee, M.K., Juzar, D.A., Moura Joaquim, R. de, Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A., Galasso, G., Arpad, L., Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A.H., Ugur Mert, K., Flores Rios, X., Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Martínez-Luengas, I.L., Boccalatte, M., Bosa Ojeda, F., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H.L., Sanchis Forés, J., Vignali, L., Pereira, H., Manzo-Silberman, S., Ordoñez, S., Arat Özkan, A., Scheller, B., Lehitola, H., Teles, R., Mantis, C., Antti, Y., Brum Silveira, J.A., Zoni, C.R., Bessonov, I., Uccello, G., Kochiadakis, G., Alexopulos, D., Uribe, C.E., Kanakakis, J., Faurie, B., Gabrielli, G., Gutierrez Barrios, A., Bachini, J.P., Rocha, Alex, Tam, F.C., Rodriguez, A., Lukito, A.A., Saint-Joy, V., Pessah, G., Tuccillo, A., Ielasi, A., Cortese, G., Parodi, G., Burgadha, M.A., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., Verdoia, M., Luca, G. De, Algowhary, M., Uguz, B., Oliveira, D.C., Ganyukov, V., Busljetik, O., Cercek, M., Jensen, L.O., Loh, P.H., Calmac, L., Ferrer, G.R.I., Quadros, A., Milewski, M., Scotto D'Uccio, F., Birgelen, C. von, Versaci, F., Berg, J ., Casella, G., Wong Sung Lung, A., Kala, P., Díez Gil, J.L., Carrillo, X., Dirksen, M., Becerra Munoz, V., Lee, M.K., Juzar, D.A., Moura Joaquim, R. de, Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A., Galasso, G., Arpad, L., Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A.H., Ugur Mert, K., Flores Rios, X., Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Martínez-Luengas, I.L., Boccalatte, M., Bosa Ojeda, F., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H.L., Sanchis Forés, J., Vignali, L., Pereira, H., Manzo-Silberman, S., Ordoñez, S., Arat Özkan, A., Scheller, B., Lehitola, H., Teles, R., Mantis, C., Antti, Y., Brum Silveira, J.A., Zoni, C.R., Bessonov, I., Uccello, G., Kochiadakis, G., Alexopulos, D., Uribe, C.E., Kanakakis, J., Faurie, B., Gabrielli, G., Gutierrez Barrios, A., Bachini, J.P., Rocha, Alex, Tam, F.C., Rodriguez, A., Lukito, A.A., Saint-Joy, V., Pessah, G., Tuccillo, A., Ielasi, A., Cortese, G., Parodi, G., Burgadha, M.A., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., and Verdoia, M.
Abstract: Contains fulltext : 291566.pdf (Publisher’s version ) (Open Access), BACKGROUND: The constraints in the management of patients with ST-segment elevation myocardial infarction (STEMI) during the COVID-19 pandemic have been suggested to have severely impacted mortality levels. The aim of the current analysis is to evaluate the age-related effects of the COVID-19 pandemic on mechanical reperfusion and 30-day mortality for STEMI within the registry ISACS-STEMI COVID-19. METHODS: This retrospective multicenter registry was performed in high-volume PPCI centers on four continents and included STEMI patients undergoing PPCI in March-June 2019 and 2020. Patients were divided according to age (< or ≥75 years). The main outcomes were the incidence and timing of PPCI, (ischemia time longer than 12 h and door-to-balloon longer than 30 min), and in-hospital or 30-day mortality. RESULTS: We included 16,683 patients undergoing PPCI in 109 centers. In 2020, during the pandemic, there was a significant reduction in PPCI as compared to 2019 (IRR 0.843 (95%-CI: 0.825-0.861, p < 0.0001). We found a significant age-related reduction (7%, p = 0.015), with a larger effect on elderly than on younger patients. Furthermore, we observed significantly higher 30-day mortality during the pandemic period, especially among the elderly (13.6% vs. 17.9%, adjusted HR (95% CI) = 1.55 [1.24-1.93], p < 0.001) as compared to younger patients (4.8% vs. 5.7%; adjusted HR (95% CI) = 1.25 [1.05-1.49], p = 0.013), as a potential consequence of the significantly longer ischemia time observed during the pandemic. CONCLUSIONS: The COVID-19 pandemic had a significant impact on the treatment of patients with STEMI, with a 16% reduction in PPCI procedures, with a larger reduction and a longer delay to treatment among elderly patients, which may have contributed to increase in-hospital and 30-day mortality during the pandemic.
Published: 2023

5. Italian Society of Interventional Cardiology (GISE) and Italian Society of Arterial Hypertension (SIIA) Consensus document on the role of renal denervation in the management of the difficult to treat hypertension [Documento di consenso della Società Italiana di Cardiologia Interventistica (GISE) e della Società Italiana dell’Ipertensione arteriosa (SIIA) sul ruolo della denervazione renale nella gestione dell’ipertensione arteriosa difficile da trattare]

Author: Stabile, E, Muiesan, M, Ribichini, F, Sangiorgi, G, Taddei, S, Versaci, F, Villari, B, Bacca, A, Benedetto, D, Fioretti, V, Liccardo, G, Laurenzano, E, Scappaticci, M, Saia, F, Tarantini, G, Grassi, G, Esposito, G, Stabile, Eugenio, Muiesan, Maria Lorenza, Ribichini, Flavio Luciano, Sangiorgi, Giuseppe, Taddei, Stefano, Versaci, Francesco, Villari, Bruno, Bacca, Alessandra, Benedetto, Daniela, Fioretti, Vincenzo, Liccardo, Gaetano, Laurenzano, Eugenio, Scappaticci, Massimiliano, Saia, Francesco, Tarantini, Giuseppe, Grassi, Guido, Esposito, Giovanni, Stabile, E, Muiesan, M, Ribichini, F, Sangiorgi, G, Taddei, S, Versaci, F, Villari, B, Bacca, A, Benedetto, D, Fioretti, V, Liccardo, G, Laurenzano, E, Scappaticci, M, Saia, F, Tarantini, G, Grassi, G, Esposito, G, Stabile, Eugenio, Muiesan, Maria Lorenza, Ribichini, Flavio Luciano, Sangiorgi, Giuseppe, Taddei, Stefano, Versaci, Francesco, Villari, Bruno, Bacca, Alessandra, Benedetto, Daniela, Fioretti, Vincenzo, Liccardo, Gaetano, Laurenzano, Eugenio, Scappaticci, Massimiliano, Saia, Francesco, Tarantini, Giuseppe, Grassi, Guido, and Esposito, Giovanni
Abstract: Arterial hypertension is the most prevalent cardiovascular risk factor worldwide. Despite the availability of many and effective antihypertensive medications, the prevalence of uncontrolled blood pressure (BP) remains high. As sympathetic hyperactivity has long been recognized as a major contributor to resistant hypertension, catheter-based renal denervation (RDN) has emerged as a new strategy to reduce BP. RDN aims to interrupt the activity of renal sympathetic nerves by applying radiofrequency (RF) energy, ultrasound (US) energy, or injection of alcohol in the perivascular space. The Symplicity HTN-3 trial, the largest sham-controlled trial using the first-generation RF-based RDN device, failed to significantly reduce BP. Since then, new devices and techniques have been developed and consequently many sham-controlled trials using second-generation RF or US-based RDN devices have demonstrated the BP lowering efficacy and safety of the procedure. A multidisciplinary team involving hypertension experts, interventionalists with expertise in renal interventions and anesthesiologists, plays a pivotal role from the selection of the patient candidate for the procedure to the post-procedural care. The aim of this consensus document is to summarize the current evidence about the use of RDN in difficult to treat hypertension and to propose a management strategy from the selection of the patient candidate for the procedure to the post-procedural care.
Published: 2023

6. Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice:: GLORIA-AF Registry

Author: Lip G. Y. H., Kotalczyk A., Teutsch C., Diener H. -C., Dubner S. J., Halperin J. L., Ma C. -S., Rothman K. J., Marler S., Gurusamy V. K., Huisman M. V., Abban D. W., Aziz E., Kalan M. B., Abdul N., Backes L. M., Bradman D., Abud A. M., Badings E., Brautigam D., Adams F., Bagni E., Breton N., Addala S., Baker S. H., Brouwers P. J. A. M., Adragao P., Bala R., Browne K., Ageno W., Baldi A., Cortada J. B., Aggarwal R., Bando S., Bruni A., Agosti S., Banerjee S., Brunschwig C., Agostoni P., Bank A., Buathier H., Aguilar F., Esquivias G. B., Buhl A., Linares J. A., Barr C., Bullinga J., Aguinaga L., Bartlett M., Cabrera J. W., Ahmed J., Basic Kes V., Caccavo A., Aiello A., Baula G., Cai S., Ainsworth P., Behrens S., Caine S., Aiub J. R., Bell A., Calo L., Al-Dallow R., Benedetti R., Calvi V., Alderson L., Mazuecos J. B., Sanchez M. C., Velasco J. A. A., Benhalima B., Candeias R., Alexopoulos D., Bergler-Klein J., Capuano V., Manterola F. A., Berneau J. -B., Capucci A., Aliyar P., Bernstein R. A., Caputo R., Alonso D., Berrospi P., Rizo T. C., da Costa F. A. A., Berti S., Cardona F., Amado J., Berz A., da Costa Darrieux F. C., Amara W., Best E., Vera Y. C. D., Amelot M., Bettencourt P., Carolei A., Amjadi N., Betzu R., Carreno S., Ammirati F., Bhagwat R., Carvalho P., Andrade M., Bhatta L., Cary S., Andrawis N., Biscione F., Casu G., Annoni G., Bisignani G., Cavallini C., Ansalone G., Black T., Cayla G., Ariani M. K., Bloch M. J., Celentano A., Arias J. C., Bloom S., Cha T. -J., Armero S., Blumberg E., Cha K. S., Arora C., Bo M., Chae J. K., Aslam M. S., Bohmer E., Chalamidas K., Asselman M., Bollmann A., Challappa K., Audouin P., Bongiorni M. G., Chand S. P., Augenbraun C., Boriani G., Chandrashekar H., Aydin S., Boswijk D. J., Chartier L., Bott J., Chatterjee K., Ayryanova I., Bottacchi E., Ayala C. A. C., Cheema A., Davis G., Evonich R., Davy J. -M., Evseeva O., Chen L., Dayer M., Ezhov A., Chen S. -A., De Biasio M., Fahmy R., Chen J. H., De Bonis S., Fang Q., Chiang F. -T., De Caterina R., Farsad R., Chiarella F., De Franceschi T., Fauchier L., Chih-Chan L., de Groot J. R., Favale S., Cho Y. K., De Horta J., Fayard M., Choi J. -I., De La Briolle A., Fedele J. L., Choi D. J., de la Pena Topete G., Fedele F., Chouinard G., de Paola A. A. V., Fedorishina O., Chow D. H. -F., de Souza W., Fera S. R., Chrysos D., de Veer A., Ferreira L. G. G., Chumakova G., De Wolf L., Ferreira J., Valenzuela E. J. J. R. C., Decoulx E., Ferri C., Nica N. C., Deepak S., Ferrier A., Cislowski D. J., Defaye P., Ferro H., Clay A., Munoz F. D. -C., Finsen A., Clifford P., Brkljacic D. D., First B., Cohen A., Deumite N. J., Fischer S., Cohen M., Di Legge S., Fonseca C., Cohen S., Diemberger I., Almeida L. F., Colivicchi F., Dietz D., Forman S., Collins R., Dionisio P., Frandsen B., Colonna P., Dong Q., French W., Compton S., dos Santos F. R., Friedman K., Connolly D., Dotcheva E., Friese A., Conti A., Doukky R., Fruntelata A. G., Buenostro G. C., D'Souza A., Fujii S., Coodley G., Dubrey S., Fumagalli S., Cooper M., Ducrocq X., Fundamenski M., Coronel J., Dupljakov D., Furukawa Y., Corso G., Duque M., Gabelmann M., Sales J. C., Dutta D., Gabra N., Cottin Y., Duvilla N., Gadsboll N., Covalesky J., Duygun A., Galinier M., Cracan A., Dziewas R., Gammelgaard A., Crea F., Eaton C. B., Ganeshkumar P., Crean P., Eaves W., Gans C., Crenshaw J., Ebels-Tuinbeek L. A., Quintana A. G., Cullen T., Ehrlich C., Gartenlaub O., Darius H., Eichinger-Hasenauer S., Gaspardone A., Dary P., Eisenberg S. J., Genz C., Dascotte O., Jabali A. E., Georger F., Dauber I., Shahawy M. E., Georges J. -L., Davalos V., Hernandes M. E., Georgeson S., Davies R., Izal A. E., Giedrimas E., Gierba M., Haruna T., Jarmukli N., Ortega I. G., Hayek E., Jeanfreau R. J., Gillespie E., Healey J., Jenkins R. D., Giniger A., Hearne S., Sanchez C. J., Giudici M. C., Heffernan M., Jimenez J., Gkotsis A., Heggelund G., Jobe R., Glotzer T. V., Heijmeriks J. A., Joen-Jakobsen T., Gmehling J., Hemels M., Jones N., Gniot J., Hendriks I., Jorge J. C. M., Goethals P., Henein S., Jouve B., Goldbarg S., Her S. -H., Jung B. C., Goldberg R., Hermany P., Jung K. T., Goldmann B., Del Rio J. E. H., Jung W., Golitsyn S., Higashino Y., Kachkovskiy M., Gomez S., Hill M., Kafkala K., Mesa J. G., Hisadome T., Kalinina L., Gonzalez V. B., Hishida E., Kallmunzer B., Hermosillo J. A. G., Hoffer E., Kamali F., Lopez V. M. G., Hoghton M., Kamo T., Gorka H., Hong K., Kampus P., Gornick C., Hong S., Kashou H., Gorog D., Horbach S., Kastrup A., Gottipaty V., Horiuchi M., Katsivas A., Goube P., Hou Y., Kaufman E., Goudevenos I., Hsing J., Kawai K., Graham B., Huang C. -H., Kawajiri K., Greer G. S., Huckins D., Kazmierski J. F., Gremmler U., Hughes K., Keeling P., Grena P. G., Huizinga A., Saraiva J. F. K., Grond M., Hulsman E. L., Ketova G., Gronda E., Hung K. -C., Khaira A. S., Gronefeld G., Hwang G. -S., Khripun A., Gu X., Ikpoh M., Kim D. -I., Torres I. G. T., Imberti D., Kim Y. H., Guardigli G., Ince H., Kim N. H., Guevara C., Indolfi C., Kim D. K., Guignier A., Inoue S., Kim J. S., Gulizia M., Irles D., Gumbley M., Iseki H., Kim K. S., Gunther A., Israel C. N., Kim J., Ha A., Iteld B., Kinova E., Hahalis G., Iyer V., Klein A., Hakas J., Jackson-Voyzey E., Kmetzo J. J., Hall C., Jaffrani N., Kneller G. L., Han B., Jager F., Knezevic A., Han S., James M., Koh S. M. A., Hargrove J., Jang S. -W., Koide S., Hargroves D., Jaramillo N., Kollias A., Kooistra J. A., Li W., McClure J., Koons J., Li X., McCormack T., Koschutnik M., Lichy C., McGarity W., Kostis W. J., Lieber I., McIntyre H., Kovacic D., Rodriguez R. H. L., McLaurin B., Kowalczyk J., Lin H., Alvaro F., Palomino M., Koziolova N., Melandri F., Kraft P., Liu F., Meno H., Kragten J. A., Liu H., Menzies D., Krantz M., Esperon G. L., Mercader M., Krause L., Navarro N. L., Meyer C., Krenning B. J., Lo E., Meyer B. J., Krikke F., Lokshyn S., Miarka J., Kromhout Z., Lopez A., Mibach F., Krysiak W., Lopez-Sendon J. L., Michalski D., Kumar P., Filho A. M. L., Michel P., Kumler T., Lorraine R. S., Chreih R. M., Kuniss M., Luengas C. A., Luengas A., Mikdadi G., Kuo J. -Y., Luke R., Mikus M., Kuppers A., Luo M., Milicic D., Kurrelmeyer K., Lupovitch S., Militaru C., Kwak C. H., Lyrer P., Minaie S., Laboulle B., Ma C., Minescu B., Labovitz A., Ma G., Mintale I., Ter Lai W., Madariaga I., Mirault T., Lam A., Maeno K., Mirro M. J., Lam Y. Y., Magnin D., Mistry D., Lanas Zanetti F., Maid G., Miu N. V., Landau C., Mainigi S. K., Miyamoto N., Landini G., Makaritsis K., Moccetti T., Lanna Figueiredo E., Malhotra R., Mohammed A., Larsen T., Manning R., Nor A. M., Lavandier K., Manolis A., Mollerus M., LeBlanc J., Hurtado H. A. M., Molon G., Lee M. H., Mantas I., Mondillo S., Lee C. -H., Jattin F. M., Moniz P., Lehman J., Maqueda V., Mont L., Leitao A., Marchionni N., Montagud V., Lellouche N., Ortuno F. M., Montana O., Lelonek M., Santana A. M., Monti C., Lenarczyk R., Martinez J., Moretti L., Lenderink T., Maskova P., Mori K., Gonzalez S. L., Hernandez N. M., Moriarty A., Leong-Sit P., Matsuda K., Morka J., Leschke M., Maurer T., Moschini L., Ley N., Mauro C., Moschos N., Li Z., May E., Mugge A., Mayer N., Mulhearn T. J., Muresan C., Jose E. P., Precoma D. B., Muriago M., Padilla F. G. P., Prelle A., Musial W., Rios V. P., Prodafikas J., Musser C. W., Pajes G., Protasov K., Musumeci F., Pandey A. S., Pye M., Nageh T., Paparella G., Qiu Z., Nakagawa H., Paris F., Quedillac J. -M., Nakamura Y., Park H. W., Raev D., Nakayama T., Park J. S., Grado C. A. R., Nam G. -B., Parthenakis F., Rahimi S., Nanna M., Passamonti E., Raisaro A., Natarajan I., Patel R. J., Rama B., Nayak H. M., Patel J., Ramos R., Naydenov S., Patel M., Ranieri M., Nazlic J., Patrick J., Raposo N., Nechita A. C., Jimenez R. P., Rashba E., Nechvatal L., Paz A., Rauch-Kroehnert U., Negron S. A., Pengo V., Reddy R., Neiman J., Pentz W., Renda G., Neuenschwander F. C., Perez B., Reza S., Neves D., Rios A. M. P., Ria L., Neykova A., Perez-Cabezas A., Richter D., Miguel R. N., Perlman R., Rickli H., Nijmeh G., Persic V., Rieker W., Nizov A., Perticone F., Vera T. R., Campos R. N., Peters T. K., Ritt L. E., Nossan J., Petkar S., Roberts D., Novikova T., Pezo L. F., Briones I. R., Nowalany-Kozielska E., Pflucke C., Escudero A. E. R., Nsah E., Pham D. N., Pascual C. R., Fragoso J. C. N., Phillips R. T., Roman M., Nurgalieva S., Phlaum S., Romeo F., Nuyens D., Pieters D., Ronner E., Nyvad O., Pineau J., Roux J. -F., de Los Rios Ibarra M. O., Pinter A., Rozkova N., O'Donnell P., Pinto F., Rubacek M., O'Donnell M., Pisters R., Rubalcava F., Oh S., Pivac N., Russo A. M., Oh Y. S., Pocanic D., Rutgers M. P., Oh D., Podoleanu C., Rybak K., O'Hara G., Politano A., Said S., Oikonomou K., Poljakovic Z., Sakamoto T., Olivares C., Pollock S., Salacata A., Oliver R., Garcea J. P., Salem A., Ruiz R. O., Poppert H., Bodes R. S., Olympios C., Porcu M., Saltzman M. A., Omaszuk-Kazberuk A., Reino A. P., Salvioni A., Asensi J. O., Prasad N., Vallejo G. S., Fernandez M. S., Sokal A., Tu T. M., Saporito W. F., Yan Y. S. O., Tuininga Y., Sarikonda K., Sotolongo R., Turakhia M., Sasaoka T., de Souza O. F., Turk S., Sati H., Sparby J. A., Turner W., Savelieva I., Spinar J., Tveit A., Scala P. -J., Sprigings D., Tytus R., Schellinger P., Spyropoulos A. C., Valadao C., Scherr C., Stakos D., van Bergen P. F. M. M., Schmitz L., Steinwender C., van de Borne P., Schmitz K. -H., Stergiou G., van den Berg B. J., Schmitz B., Stiell I., van der Zwaan C., Schnabel T., Stoddard M., Van Eck M., Schnupp S., Stoikov A., Vanacker P., Schoeniger P., Streb W., Vasilev D., Schon N., Styliadis I., Vasilikos V., Schwimmbeck P., Su G., Vasilyev M., Seamark C., Su X., Veerareddy S., Searles G., Sudnik W., Mino M. V., Seidl K. -H., Sukles K., Venkataraman A., Seidman B., Sun X., Verdecchia P., Sek J., Swart H., Versaci F., Sekaran L., Szavits-Nossan J., Vester E. G., Serrati C., Taggeselle J., Vial H., Shah N., Takagi Y., Victory J., Shah V., Takhar A. P. S., Villamil A., Shah A., Tamm A., Vincent M., Shah S., Tanaka K., Vlastaris A., Sharma V. K., Tanawuttiwat T., Dahl J., Shaw L., Tang S., Vora K., Sheikh K. H., Tang A., Vranian R. B., Shimizu N., Tarsi G., Wakefield P., Shimomura H., Tassinari T., Wang N., Shin D. -G., Tayal A., Wang M., Shin E. -S., Tayebjee M., Wang X., Shite J., Berg J. M., Wang F., Sibilio G., Tesloianu D., Wang T., Silver F., The S. H. K., Warner A. L., Sime I., Thomas D., Watanabe K., Simmers T. A., Timsit S., Wei J., Singh N., Tobaru T., Weimar C., Siostrzonek P., Tomasik A. R., Weiner S., Smadja D., Torosoff M., Weinrich R., Smith D. W., Touze E., Wen M. -S., Snitman M., Trendafilova E., Wiemer M., Filho D. S., Tsai W. K., Wiggers P., Soda H., Tse H. F., Wilke A., Sofley C., Tsutsui H., Williams D., Williams M. L., Yan P. Y. B., Zhang P., Witzenbichler B., Yang T., Zhang J., Wong B., Yao J., Zhao S. P., Wong K. S. L., Yeh K. -H., Zhao Y., Wozakowska-Kaplon B., Yin W. H., Zhao Z., Wu S., Yotov Y., Zheng Y., Wu R. C., Zahn R., Zhou J., Wunderlich S., Zarich S., Zimmermann S., Wyatt N., Zenin S., Zini A., Wylie J., Zeuthen E. L., Zizzo S., Xu Y., Zhang H., Zong W., Xu X., Zhang D., Zukerman L. S., Yamanoue H., Zhang X., Yamashita T., Cardiology, ACS - Heart failure & arrhythmias, Lip G.Y.H., Kotalczyk A., Teutsch C., Diener H.-C., Dubner S.J., Halperin J.L., Ma C.-S., Rothman K.J., Marler S., Gurusamy V.K., Huisman M.V., Abban D.W., Aziz E., Kalan M.B., Abdul N., Backes L.M., Bradman D., Abud A.M., Badings E., Brautigam D., Adams F., Bagni E., Breton N., Addala S., Baker S.H., Brouwers P.J.A.M., Adragao P., Bala R., Browne K., Ageno W., Baldi A., Cortada J.B., Aggarwal R., Bando S., Bruni A., Agosti S., Banerjee S., Brunschwig C., Agostoni P., Bank A., Buathier H., Aguilar F., Esquivias G.B., Buhl A., Linares J.A., Barr C., Bullinga J., Aguinaga L., Bartlett M., Cabrera J.W., Ahmed J., Basic Kes V., Caccavo A., Aiello A., Baula G., Cai S., Ainsworth P., Behrens S., Caine S., Aiub J.R., Bell A., Calo L., Al-Dallow R., Benedetti R., Calvi V., Alderson L., Mazuecos J.B., Sanchez M.C., Velasco J.A.A., Benhalima B., Candeias R., Alexopoulos D., Bergler-Klein J., Capuano V., Manterola F.A., Berneau J.-B., Capucci A., Aliyar P., Bernstein R.A., Caputo R., Alonso D., Berrospi P., Rizo T.C., da Costa F.A.A., Berti S., Cardona F., Amado J., Berz A., da Costa Darrieux F.C., Amara W., Best E., Vera Y.C.D., Amelot M., Bettencourt P., Carolei A., Amjadi N., Betzu R., Carreno S., Ammirati F., Bhagwat R., Carvalho P., Andrade M., Bhatta L., Cary S., Andrawis N., Biscione F., Casu G., Annoni G., Bisignani G., Cavallini C., Ansalone G., Black T., Cayla G., Ariani M.K., Bloch M.J., Celentano A., Arias J.C., Bloom S., Cha T.-J., Armero S., Blumberg E., Cha K.S., Arora C., Bo M., Chae J.K., Aslam M.S., Bohmer E., Chalamidas K., Asselman M., Bollmann A., Challappa K., Audouin P., Bongiorni M.G., Chand S.P., Augenbraun C., Boriani G., Chandrashekar H., Aydin S., Boswijk D.J., Chartier L., Bott J., Chatterjee K., Ayryanova I., Bottacchi E., Ayala C.A.C., Cheema A., Davis G., Evonich R., Davy J.-M., Evseeva O., Chen L., Dayer M., Ezhov A., Chen S.-A., De Biasio M., Fahmy R., Chen J.H., De Bonis S., Fang Q., Chiang F.-T., De Caterina R., Farsad R., Chiarella F., De Franceschi T., Fauchier L., Chih-Chan L., de Groot J.R., Favale S., Cho Y.K., De Horta J., Fayard M., Choi J.-I., De La Briolle A., Fedele J.L., Choi D.J., de la Pena Topete G., Fedele F., Chouinard G., de Paola A.A.V., Fedorishina O., Chow D.H.-F., de Souza W., Fera S.R., Chrysos D., de Veer A., Ferreira L.G.G., Chumakova G., De Wolf L., Ferreira J., Valenzuela E.J.J.R.C., Decoulx E., Ferri C., Nica N.C., Deepak S., Ferrier A., Cislowski D.J., Defaye P., Ferro H., Clay A., Munoz F.D.-C., Finsen A., Clifford P., Brkljacic D.D., First B., Cohen A., Deumite N.J., Fischer S., Cohen M., Di Legge S., Fonseca C., Cohen S., Diemberger I., Almeida L.F., Colivicchi F., Dietz D., Forman S., Collins R., Dionisio P., Frandsen B., Colonna P., Dong Q., French W., Compton S., dos Santos F.R., Friedman K., Connolly D., Dotcheva E., Friese A., Conti A., Doukky R., Fruntelata A.G., Buenostro G.C., D'Souza A., Fujii S., Coodley G., Dubrey S., Fumagalli S., Cooper M., Ducrocq X., Fundamenski M., Coronel J., Dupljakov D., Furukawa Y., Corso G., Duque M., Gabelmann M., Sales J.C., Dutta D., Gabra N., Cottin Y., Duvilla N., Gadsboll N., Covalesky J., Duygun A., Galinier M., Cracan A., Dziewas R., Gammelgaard A., Crea F., Eaton C.B., Ganeshkumar P., Crean P., Eaves W., Gans C., Crenshaw J., Ebels-Tuinbeek L.A., Quintana A.G., Cullen T., Ehrlich C., Gartenlaub O., Darius H., Eichinger-Hasenauer S., Gaspardone A., Dary P., Eisenberg S.J., Genz C., Dascotte O., Jabali A.E., Georger F., Dauber I., Shahawy M.E., Georges J.-L., Davalos V., Hernandes M.E., Georgeson S., Davies R., Izal A.E., Giedrimas E., Gierba M., Haruna T., Jarmukli N., Ortega I.G., Hayek E., Jeanfreau R.J., Gillespie E., Healey J., Jenkins R.D., Giniger A., Hearne S., Sanchez C.J., Giudici M.C., Heffernan M., Jimenez J., Gkotsis A., Heggelund G., Jobe R., Glotzer T.V., Heijmeriks J.A., Joen-Jakobsen T., Gmehling J., Hemels M., Jones N., Gniot J., Hendriks I., Jorge J.C.M., Goethals P., Henein S., Jouve B., Goldbarg S., Her S.-H., Jung B.C., Goldberg R., Hermany P., Jung K.T., Goldmann B., Del Rio J.E.H., Jung W., Golitsyn S., Higashino Y., Kachkovskiy M., Gomez S., Hill M., Kafkala K., Mesa J.G., Hisadome T., Kalinina L., Gonzalez V.B., Hishida E., Kallmunzer B., Hermosillo J.A.G., Hoffer E., Kamali F., Lopez V.M.G., Hoghton M., Kamo T., Gorka H., Hong K., Kampus P., Gornick C., Hong S., Kashou H., Gorog D., Horbach S., Kastrup A., Gottipaty V., Horiuchi M., Katsivas A., Goube P., Hou Y., Kaufman E., Goudevenos I., Hsing J., Kawai K., Graham B., Huang C.-H., Kawajiri K., Greer G.S., Huckins D., Kazmierski J.F., Gremmler U., Hughes K., Keeling P., Grena P.G., Huizinga A., Saraiva J.F.K., Grond M., Hulsman E.L., Ketova G., Gronda E., Hung K.-C., Khaira A.S., Gronefeld G., Hwang G.-S., Khripun A., Gu X., Ikpoh M., Kim D.-I., Torres I.G.T., Imberti D., Kim Y.H., Guardigli G., Ince H., Kim N.H., Guevara C., Indolfi C., Kim D.K., Guignier A., Inoue S., Kim J.S., Gulizia M., Irles D., Gumbley M., Iseki H., Kim K.S., Gunther A., Israel C.N., Kim J., Ha A., Iteld B., Kinova E., Hahalis G., Iyer V., Klein A., Hakas J., Jackson-Voyzey E., Kmetzo J.J., Hall C., Jaffrani N., Kneller G.L., Han B., Jager F., Knezevic A., Han S., James M., Koh S.M.A., Hargrove J., Jang S.-W., Koide S., Hargroves D., Jaramillo N., Kollias A., Kooistra J.A., Li W., McClure J., Koons J., Li X., McCormack T., Koschutnik M., Lichy C., McGarity W., Kostis W.J., Lieber I., McIntyre H., Kovacic D., Rodriguez R.H.L., McLaurin B., Kowalczyk J., Lin H., Alvaro F., Palomino M., Koziolova N., Melandri F., Kraft P., Liu F., Meno H., Kragten J.A., Liu H., Menzies D., Krantz M., Esperon G.L., Mercader M., Krause L., Navarro N.L., Meyer C., Krenning B.J., Lo E., Meyer B.J., Krikke F., Lokshyn S., Miarka J., Kromhout Z., Lopez A., Mibach F., Krysiak W., Lopez-Sendon J.L., Michalski D., Kumar P., Filho A.M.L., Michel P., Kumler T., Lorraine R.S., Chreih R.M., Kuniss M., Luengas C.A., Luengas A., Mikdadi G., Kuo J.-Y., Luke R., Mikus M., Kuppers A., Luo M., Milicic D., Kurrelmeyer K., Lupovitch S., Militaru C., Kwak C.H., Lyrer P., Minaie S., Laboulle B., Ma C., Minescu B., Labovitz A., Ma G., Mintale I., Ter Lai W., Madariaga I., Mirault T., Lam A., Maeno K., Mirro M.J., Lam Y.Y., Magnin D., Mistry D., Lanas Zanetti F., Maid G., Miu N.V., Landau C., Mainigi S.K., Miyamoto N., Landini G., Makaritsis K., Moccetti T., Lanna Figueiredo E., Malhotra R., Mohammed A., Larsen T., Manning R., Nor A.M., Lavandier K., Manolis A., Mollerus M., LeBlanc J., Hurtado H.A.M., Molon G., Lee M.H., Mantas I., Mondillo S., Lee C.-H., Jattin F.M., Moniz P., Lehman J., Maqueda V., Mont L., Leitao A., Marchionni N., Montagud V., Lellouche N., Ortuno F.M., Montana O., Lelonek M., Santana A.M., Monti C., Lenarczyk R., Martinez J., Moretti L., Lenderink T., Maskova P., Mori K., Gonzalez S.L., Hernandez N.M., Moriarty A., Leong-Sit P., Matsuda K., Morka J., Leschke M., Maurer T., Moschini L., Ley N., Mauro C., Moschos N., Li Z., May E., Mugge A., Mayer N., Mulhearn T.J., Muresan C., Jose E.P., Precoma D.B., Muriago M., Padilla F.G.P., Prelle A., Musial W., Rios V.P., Prodafikas J., Musser C.W., Pajes G., Protasov K., Musumeci F., Pandey A.S., Pye M., Nageh T., Paparella G., Qiu Z., Nakagawa H., Paris F., Quedillac J.-M., Nakamura Y., Park H.W., Raev D., Nakayama T., Park J.S., Grado C.A.R., Nam G.-B., Parthenakis F., Rahimi S., Nanna M., Passamonti E., Raisaro A., Natarajan I., Patel R.J., Rama B., Nayak H.M., Patel J., Ramos R., Naydenov S., Patel M., Ranieri M., Nazlic J., Patrick J., Raposo N., Nechita A.C., Jimenez R.P., Rashba E., Nechvatal L., Paz A., Rauch-Kroehnert U., Negron S.A., Pengo V., Reddy R., Neiman J., Pentz W., Renda G., Neuenschwander F.C., Perez B., Reza S., Neves D., Rios A.M.P., Ria L., Neykova A., Perez-Cabezas A., Richter D., Miguel R.N., Perlman R., Rickli H., Nijmeh G., Persic V., Rieker W., Nizov A., Perticone F., Vera T.R., Campos R.N., Peters T.K., Ritt L.E., Nossan J., Petkar S., Roberts D., Novikova T., Pezo L.F., Briones I.R., Nowalany-Kozielska E., Pflucke C., Escudero A.E.R., Nsah E., Pham D.N., Pascual C.R., Fragoso J.C.N., Phillips R.T., Roman M., Nurgalieva S., Phlaum S., Romeo F., Nuyens D., Pieters D., Ronner E., Nyvad O., Pineau J., Roux J.-F., de Los Rios Ibarra M.O., Pinter A., Rozkova N., O'Donnell P., Pinto F., Rubacek M., O'Donnell M., Pisters R., Rubalcava F., Oh S., Pivac N., Russo A.M., Oh Y.S., Pocanic D., Rutgers M.P., Oh D., Podoleanu C., Rybak K., O'Hara G., Politano A., Said S., Oikonomou K., Poljakovic Z., Sakamoto T., Olivares C., Pollock S., Salacata A., Oliver R., Garcea J.P., Salem A., Ruiz R.O., Poppert H., Bodes R.S., Olympios C., Porcu M., Saltzman M.A., Omaszuk-Kazberuk A., Reino A.P., Salvioni A., Asensi J.O., Prasad N., Vallejo G.S., Fernandez M.S., Sokal A., Tu T.M., Saporito W.F., Yan Y.S.O., Tuininga Y., Sarikonda K., Sotolongo R., Turakhia M., Sasaoka T., de Souza O.F., Turk S., Sati H., Sparby J.A., Turner W., Savelieva I., Spinar J., Tveit A., Scala P.-J., Sprigings D., Tytus R., Schellinger P., Spyropoulos A.C., Valadao C., Scherr C., Stakos D., van Bergen P.F.M.M., Schmitz L., Steinwender C., van de Borne P., Schmitz K.-H., Stergiou G., van den Berg B.J., Schmitz B., Stiell I., van der Zwaan C., Schnabel T., Stoddard M., Van Eck M., Schnupp S., Stoikov A., Vanacker P., Schoeniger P., Streb W., Vasilev D., Schon N., Styliadis I., Vasilikos V., Schwimmbeck P., Su G., Vasilyev M., Seamark C., Su X., Veerareddy S., Searles G., Sudnik W., Mino M.V., Seidl K.-H., Sukles K., Venkataraman A., Seidman B., Sun X., Verdecchia P., Sek J., Swart H., Versaci F., Sekaran L., Szavits-Nossan J., Vester E.G., Serrati C., Taggeselle J., Vial H., Shah N., Takagi Y., Victory J., Shah V., Takhar A.P.S., Villamil A., Shah A., Tamm A., Vincent M., Shah S., Tanaka K., Vlastaris A., Sharma V.K., Tanawuttiwat T., Dahl J., Shaw L., Tang S., Vora K., Sheikh K.H., Tang A., Vranian R.B., Shimizu N., Tarsi G., Wakefield P., Shimomura H., Tassinari T., Wang N., Shin D.-G., Tayal A., Wang M., Shin E.-S., Tayebjee M., Wang X., Shite J., Berg J.M., Wang F., Sibilio G., Tesloianu D., Wang T., Silver F., The S.H.K., Warner A.L., Sime I., Thomas D., Watanabe K., Simmers T.A., Timsit S., Wei J., Singh N., Tobaru T., Weimar C., Siostrzonek P., Tomasik A.R., Weiner S., Smadja D., Torosoff M., Weinrich R., Smith D.W., Touze E., Wen M.-S., Snitman M., Trendafilova E., Wiemer M., Filho D.S., Tsai W.K., Wiggers P., Soda H., Tse H.F., Wilke A., Sofley C., Tsutsui H., Williams D., Williams M.L., Yan P.Y.B., Zhang P., Witzenbichler B., Yang T., Zhang J., Wong B., Yao J., Zhao S.P., Wong K.S.L., Yeh K.-H., Zhao Y., Wozakowska-Kaplon B., Yin W.H., Zhao Z., Wu S., Yotov Y., Zheng Y., Wu R.C., Zahn R., Zhou J., Wunderlich S., Zarich S., Zimmermann S., Wyatt N., Zenin S., Zini A., Wylie J., Zeuthen E.L., Zizzo S., Xu Y., Zhang H., Zong W., Xu X., Zhang D., Zukerman L.S., Yamanoue H., Zhang X., and Yamashita T.
Subjects: Apixaban, Atrial fibrillation, Dabigatran, Non-vitamin K antagonists, Rivaroxaban, Pyridones, Medizin, Myocardial Infarction, Administration, Oral, Anticoagulants, Hemorrhage, General Medicine, Non-vitamin K antagonist, Stroke, Clinical Trials, Phase III as Topic, Humans, Prospective Studies, Registries, Cardiology and Cardiovascular Medicine
Abstract: Background and purpose Prospectively collected data comparing the safety and effectiveness of individual non-vitamin K antagonists (NOACs) are lacking. Our objective was to directly compare the effectiveness and safety of NOACs in patients with newly diagnosed atrial fibrillation (AF). Methods In GLORIA-AF, a large, prospective, global registry program, consecutive patients with newly diagnosed AF were followed for 3 years. The comparative analyses for (1) dabigatran vs rivaroxaban or apixaban and (2) rivaroxaban vs apixaban were performed on propensity score (PS)-matched patient sets. Proportional hazards regression was used to estimate hazard ratios (HRs) for outcomes of interest. Results The GLORIA-AF Phase III registry enrolled 21,300 patients between January 2014 and December 2016. Of these, 3839 were prescribed dabigatran, 4015 rivaroxaban and 4505 apixaban, with median ages of 71.0, 71.0, and 73.0 years, respectively. In the PS-matched set, the adjusted HRs and 95% confidence intervals (CIs) for dabigatran vs rivaroxaban were, for stroke: 1.27 (0.79–2.03), major bleeding 0.59 (0.40–0.88), myocardial infarction 0.68 (0.40–1.16), and all-cause death 0.86 (0.67–1.10). For the comparison of dabigatran vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 1.16 (0.76–1.78), myocardial infarction 0.84 (0.48–1.46), major bleeding 0.98 (0.63–1.52) and all-cause death 1.01 (0.79–1.29). For the comparison of rivaroxaban vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 0.78 (0.52–1.19), myocardial infarction 0.96 (0.63–1.45), major bleeding 1.54 (1.14–2.08), and all-cause death 0.97 (0.80–1.19). Conclusions Patients treated with dabigatran had a 41% lower risk of major bleeding compared with rivaroxaban, but similar risks of stroke, MI, and death. Relative to apixaban, patients treated with dabigatran had similar risks of stroke, major bleeding, MI, and death. Rivaroxaban relative to apixaban had increased risk for major bleeding, but similar risks for stroke, MI, and death. Registration URL: https://www.clinicaltrials.gov. Unique identifiers: NCT01468701, NCT01671007. Date of registration: September 2013. Graphical abstract
Published: 2022
Full Text: View/download PDF

7. COVID-19 pandemic, mechanical reperfusion and 30-day mortality in ST elevation myocardial infarction

Author: De Luca G, Algowhary M, Uguz B, Oliveira DC, Ganyukov V, Zimbakov Z, Cercek M, Jensen LO, Loh PH, Calmac L, Roura-Ferrer G, Quadros A, Milewski M, Scotto di Uccio F, von Birgelen C, Versaci F, Ten Berg J, Casella G, Wong ASL, Kala P, Diez Gil JL, Carrillo X, Dirksen MT, Becerra-Muñoz VM, Kang-Yin Lee M, Juzar DA, de Moura Joaquim R, Paladino R, Milicic D, Davlouros P, Bakraceski N, Zilio F, Donazzan L, Kraaijeveld AO, Galasso G, Lux A, Marinucci L, Guiducci V, Menichelli M, Scoccia A, Yamac A, Ugur Mert K, Flores Rios X, Kovarnik T, Kidawa M, Moreu J, Flavien V, Fabris E, Lozano Martìnez-Luengas I, Boccalatte M, Bosa Ojeda F, Arellano-Serrano C, Caiazzo G, Cirrincione G, Kao HL, Sanchis Fores J, Vignali L, Pereira H, Manzo-Silberman S, Ordonez S, Özkan AA, Scheller B, Lehtola H, Teles R, Mantis C, Ylitalo A, Brum Silveira JA, Zoni R, Bessonov I, Savonitto S, Kochiadakis G, Alexopoulos D, Uribe C, Kanakakis J, Faurie B, Gabrielli G, Gutiérrez A, Bachini JP, Rocha A, Tam FC, Rodriguez A, Lukito A, Saint-Joy V, Pessah G, Tuccillo B, Cortese G, Parodi G, Bouraghda MA, Kedhi E, Lamelas P, Suryapranata H, Nardin M, Verdoia M, ISACS-STEMI COVID-19, Collaborators, RS: Carim - H01 Clinical atrial fibrillation, Cardiologie, De Luca, G., Algowhary, M., Uguz, B., Oliveira, D. C., Ganyukov, V., Zimbakov, Z., Cercek, M., Jensen, L. O., Loh, P. H., Calmac, L., Roura-Ferrer, G., Quadros, A., Milewski, M., Scotto di Uccio, F., von Birgelen, C., Versaci, F., Ten Berg, J., Casella, G., Wong, A. S. L., Kala, P., Diez Gil, J. L., Carrillo, X., Dirksen, M. T., Becerra-Munoz, V. M., Kang-Yin Lee, M., Juzar, D. A., de Moura Joaquim, R., Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A. O., Galasso, G., Lux, A., Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A., Ugur Mert, K., Flores Rios, X., Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Lozano Martinez-Luengas, I., Boccalatte, M., Bosa Ojeda, F., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H. -L., Sanchis Fores, J., Vignali, L., Pereira, H., Manzo-Silberman, S., Ordonez, S., Ozkan, A. A., Scheller, B., Lehtola, H., Teles, R., Mantis, C., Ylitalo, A., Brum Silveira, J. A., Zoni, R., Bessonov, I., Savonitto, S., Kochiadakis, G., Alexopoulos, D., Uribe, C., Kanakakis, J., Faurie, B., Gabrielli, G., Gutierrez, A., Bachini, J. P., Rocha, A., Tam, F. C., Rodriguez, A., Lukito, A., Saint-Joy, V., Pessah, G., Tuccillo, B., Cortese, G., Parodi, G., Bouraghda, M. A., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., and Verdoia, M.
Subjects: Registrie, Male, ST Elevation Myocardial Infarction/diagnosis, Time Factors, Percutaneous, medicine.medical_treatment, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Coronary Artery Disease, Practice Patterns, 030204 cardiovascular system & hematology, Rate ratio, Time-to-Treatment/trends, Cardiologists, 0302 clinical medicine, Retrospective Studie, Heart Rate, Risk Factors, Pandemic, ST segment, Registries, Hospital Mortality, 030212 general & internal medicine, Myocardial infarction, Practice Patterns, Physicians', 10. No inequality, Percutaneous Coronary Intervention/adverse effects, Hospital Mortality/trends, COVID-19, myocardial infarction, percutaneous coronary intervention, Incidence, Incidence (epidemiology), Middle Aged, 3. Good health, Treatment Outcome, Cardiology, Female, Cardiology and Cardiovascular Medicine, Cardiologists/trends, Human, Aged, Humans, Percutaneous Coronary Intervention, Retrospective Studies, Risk Assessment, ST Elevation Myocardial Infarction, Time-to-Treatment, medicine.medical_specialty, Time Factor, Coronavirus disease 2019 (COVID-19), Cardiologist, 03 medical and health sciences, Internal medicine, medicine, Acute Coronary Syndrome, Pandemics, Physicians', SARS-CoV-2, business.industry, Risk Factor, COVID-19, myocardial infarction, percutaneous coronary intervention, Percutaneous coronary intervention, medicine.disease, Practice Patterns, Physicians'/trends, business
Abstract: ObjectiveThe initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction in primary percutaneous coronary intervention procedures and higher in-hospital mortality during the initial phase of the pandemic as compared with the prepandemic period. The aim of the current study was to provide the final results of the registry, subsequently extended outside Europe with a larger inclusion period (up to June 2020) and longer follow-up (up to 30 days).MethodsThis is a retrospective multicentre registry in 109 high-volume primary percutaneous coronary intervention (PPCI) centres from Europe, Latin America, South-East Asia and North Africa, enrolling 16 674 patients with ST segment elevation myocardial infarction (STEMI) undergoing PPPCI in March/June 2019 and 2020. The main study outcomes were the incidence of PPCI, delayed treatment (ischaemia time >12 hours and door-to-balloon >30 min), in-hospital and 30-day mortality.ResultsIn 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio 0.843, 95% CI 0.825 to 0.861, p75 years) (p=0.015), and was not related to the peak of cases or deaths due to COVID-19. The heterogeneity among centres was high (pConclusionPercutaneous revascularisation for STEMI was significantly affected by the COVID-19 pandemic, with a 16% reduction in PPCI procedures, especially among older patients (about 20%), and longer delays to treatment, which may have contributed to the increased in-hospital and 30-day mortality during the pandemic.Trial registration numberNCT04412655.
Published: 2022
Full Text: View/download PDF

8. Morphological and clinical implications of the optical coherence tomography-derived lipid core burden index

Author: Biccire, F G, primary, Budassi, S, additional, Ozaki, Y, additional, Boi, A, additional, Romagnoli, E, additional, Di Pietro, R, additional, Debelak, C, additional, Sammartini, E, additional, Versaci, F, additional, Fabbiocchi, F, additional, Burzotta, F, additional, Crea, F, additional, Arbustini, E, additional, Alfonso, F, additional, and Prati, F, additional
Published: 2022
Full Text: View/download PDF

9. Leveraging cluster analysis of weather and pollution features to predict acute cardiac or cerebrovascular events

Author: Testa, A, primary, Anticoli, S, additional, Pezzella, FR, additional, Mangiardi, M, additional, Di Giosa, A, additional, Marchegiani, G, additional, Frati, G, additional, Sciarretta, S, additional, Peruzzi, M, additional, Cavarretta, E, additional, Gaspardone, A, additional, Mariano, E, additional, Versaci, B, additional, Versaci, F, additional, and Biondi-Zoccai, G, additional
Published: 2022
Full Text: View/download PDF

10. COVID-19 pandemic, mechanical reperfusion and 30-day mortality in ST elevation myocardial infarction

Author: Luca, G. De, Algowhary, M., Uguz, B., Oliveira, D.C., Ganyukov, V., Zimbakov, Z., Cercek, M., Jensen, L.O., Loh, P.H., Calmac, L., Roura-Ferrer, G., Quadros, A., Milewski, M., Uccio, F. Scotto di, Birgelen, C. von, Versaci, F., Berg, J ., Casella, G., Wong, A.S.Y., Kala, P., Gil, J.L. Diez, Carrillo, X., Dirksen, M.T., Becerra-Muñoz, V.M., Kang-Yin Lee, M., Juzar, D.A., Joaquim, R. de Moura, Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A.O., Galasso, G., Lux, A, Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A., Mert, K. Ugur, Rios, X. Flores, Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Martìnez-Luengas, I. Lozano, Boccalatte, M., Ojeda, F., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H.L., Fores, J. Sanchis, Vignali, L., Pereira, H., Manzo-Silberman, S., Ordonez, S., Özkan, A.A., Scheller, B., Lehtola, H., Teles, R., Mantis, C., Ylitalo, A., Silveira, J.A. Brum, Zoni, R., Bessonov, I., Savonitto, S., Kochiadakis, G., Alexopoulos, D., Uribe, C., Kanakakis, J., Faurie, B., Gabrielli, G., Gutiérrez, A., Bachini, J.P., Rocha, A., Tam, F.C., Rodriguez, A., Lukito, A., Saint-Joy, V., Pessah, G., Tuccillo, B., Cortese, G., Parodi, G., Bouraghda, M.A., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., Verdoia, M., Luca, G. De, Algowhary, M., Uguz, B., Oliveira, D.C., Ganyukov, V., Zimbakov, Z., Cercek, M., Jensen, L.O., Loh, P.H., Calmac, L., Roura-Ferrer, G., Quadros, A., Milewski, M., Uccio, F. Scotto di, Birgelen, C. von, Versaci, F., Berg, J ., Casella, G., Wong, A.S.Y., Kala, P., Gil, J.L. Diez, Carrillo, X., Dirksen, M.T., Becerra-Muñoz, V.M., Kang-Yin Lee, M., Juzar, D.A., Joaquim, R. de Moura, Paladino, R., Milicic, D., Davlouros, P., Bakraceski, N., Zilio, F., Donazzan, L., Kraaijeveld, A.O., Galasso, G., Lux, A, Marinucci, L., Guiducci, V., Menichelli, M., Scoccia, A., Yamac, A., Mert, K. Ugur, Rios, X. Flores, Kovarnik, T., Kidawa, M., Moreu, J., Flavien, V., Fabris, E., Martìnez-Luengas, I. Lozano, Boccalatte, M., Ojeda, F., Arellano-Serrano, C., Caiazzo, G., Cirrincione, G., Kao, H.L., Fores, J. Sanchis, Vignali, L., Pereira, H., Manzo-Silberman, S., Ordonez, S., Özkan, A.A., Scheller, B., Lehtola, H., Teles, R., Mantis, C., Ylitalo, A., Silveira, J.A. Brum, Zoni, R., Bessonov, I., Savonitto, S., Kochiadakis, G., Alexopoulos, D., Uribe, C., Kanakakis, J., Faurie, B., Gabrielli, G., Gutiérrez, A., Bachini, J.P., Rocha, A., Tam, F.C., Rodriguez, A., Lukito, A., Saint-Joy, V., Pessah, G., Tuccillo, B., Cortese, G., Parodi, G., Bouraghda, M.A., Kedhi, E., Lamelas, P., Suryapranata, H., Nardin, M., and Verdoia, M.
Abstract: Item does not contain fulltext, OBJECTIVE: The initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction in primary percutaneous coronary intervention procedures and higher in-hospital mortality during the initial phase of the pandemic as compared with the prepandemic period. The aim of the current study was to provide the final results of the registry, subsequently extended outside Europe with a larger inclusion period (up to June 2020) and longer follow-up (up to 30 days). METHODS: This is a retrospective multicentre registry in 109 high-volume primary percutaneous coronary intervention (PPCI) centres from Europe, Latin America, South-East Asia and North Africa, enrolling 16 674 patients with ST segment elevation myocardial infarction (STEMI) undergoing PPPCI in March/June 2019 and 2020. The main study outcomes were the incidence of PPCI, delayed treatment (ischaemia time >12 hours and door-to-balloon >30 min), in-hospital and 30-day mortality. RESULTS: In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio 0.843, 95% CI 0.825 to 0.861, p<0.0001). This reduction was significantly associated with age, being higher in older adults (>75 years) (p=0.015), and was not related to the peak of cases or deaths due to COVID-19. The heterogeneity among centres was high (p<0.001). Furthermore, the pandemic was associated with a significant increase in door-to-balloon time (40 (25-70) min vs 40 (25-64) min, p=0.01) and total ischaemia time (225 (135-410) min vs 196 (120-355) min, p<0.001), which may have contributed to the higher in-hospital (6.5% vs 5.3%, p<0.001) and 30-day (8% vs 6.5%, p=0.001) mortality observed during the pandemic. CONCLUSION: Percutaneous revascularisation for STEMI was significantly affected by the COVID-19 pandemic, with a 16% reduction in PPCI procedures, especially among older patients (about 20%), and longer delays to treatmen
Published: 2022

11. The Role of the Association Between Serum C-Reactive Protein Levels and Coronary Plaque Macrophage Accumulation in Predicting Clinical Events — Results from the CLIMA Registry

Author: Budassi, S., Biccire, F. G., Paoletti, G., Marco, V., Boi, A., Romagnoli, Elisa, Fabbiocchi, F., Fineschi, M., Di Pietro, R., Versaci, F., Calligaris, G., Gatto, L., Albertucci, M., Ramazzotti, V., Burzotta, Francesco, Ozaki, Y., Arbustini, E., Alfonso, F., Prati, Francesco, Romagnoli E., Burzotta F. (ORCID:0000-0002-6569-9401), Prati F., Budassi, S., Biccire, F. G., Paoletti, G., Marco, V., Boi, A., Romagnoli, Elisa, Fabbiocchi, F., Fineschi, M., Di Pietro, R., Versaci, F., Calligaris, G., Gatto, L., Albertucci, M., Ramazzotti, V., Burzotta, Francesco, Ozaki, Y., Arbustini, E., Alfonso, F., Prati, Francesco, Romagnoli E., Burzotta F. (ORCID:0000-0002-6569-9401), and Prati F.
Abstract: The present investigation aims to study the interaction between systemic and intra-plaque inflammation in predicting cardiac events. We investigated C-reactive protein (CRP) levels as well as plaque inflammation with optical coherence tomography (OCT)-detected macrophages in the CLIMA study. 689 patients had admission CRP serum values reported, and high CRP values were defined as ≥ 2 mg/dl. The main study endpoint was a composite of cardiac death, myocardial infarction, and/or target vessel revascularization at 1-year follow-up. At multivariate Cox regression analysis, a large (hazard ratio [HR] 2.27, 95% confidence interval [CI] 1.2–4.3; p = 0.013) and superficial (HR 2.78, 95%CI 1.5–5.1; p = 0.001) macrophage arc was predicted of the main composite endpoint in patients with high CRP levels. Patients with large/superficial macrophage accumulation and low CRP levels were not at higher risk of adverse events. The presence of high CRP levels and large/superficial macrophage accumulation at OCT analysis identified patients at higher risk of clinical events. Graphical abstract: [Figure not available: see fulltext.]
Published: 2022

12. Carotid artery stenting: findings based on 8 years’ experience

Author: Simonetti, G., Gandini, R., Versaci, F., Pampana, E., Fabiano, S., Stefanini, M., Spinelli, A., Reale, C. A., Di Primio, M., and Gaspari, E.
Published: 2009
Full Text: View/download PDF

13. Retinal image quality with multifocal, EDoF, and accommodative intraocular lenses as studied by pyramidal aberrometry

Author: Alio J, D'Oria F, Toto F, Balgos J, Palazon A, Versaci F, and del Barrio J
Subjects: Multifocal IOL, Pyramidal aberrometry, Accommodative IOL, Extended depth of focus, Cataract surgery
Abstract: Background To study and compare the clinical optical image quality following implantation with different premium IOLs by analysing the point spread function (PSF) Strehl ratio using a pyramidal wavefront sensor (PWS)-based aberrometer. Methods This study included 194 eyes implanted with: (a) 19 AcrySof SA60AT (control group); (b) 19 Miniwell; (c) 24 LENTIS Mplus LS-313 MF30; d) 33 LENTIS Mplus LS-313 MF15; (e) 17 AkkoLens Lumina; (f) 31 AT LISA Tri 839MP; (g) 20 Precizon Presbyopic; (h) 20 AcrySof IQ PanOptix; (i) 11 Tecnis Eyhance. Main outcome measures were PSF Strehl ratio, PSF Strehl ratio excluding second-order aberrations (PSFw2), total root mean square (RMS), low-order aberration (LOA) and high-order aberration (HOA) RMS measured by PWS aberrometer. Results AT LISA Tri had the highest PSFw2 Strehl ratio at both 3.0- and 4.0-mm pupil size (0.52 +/- 0.14 and 0.31 +/- 0.10; P < 0.05), followed by SA60AT (0.41 +/- 0.11 and 0.28 +/- 0.07) and PanOptix (0.4 +/- 0.07 and 0.26 +/- 0.04). AT LISA Tri was found to provide a significantly better retinal image quality than PanOptix at both 3.0 mm (P < 0.0001) and 4.0 mm (P = 0.004). Mplus MF15 was found to be significantly better than Mplus MF30 at both 3.0 mm (P < 0.0001) and 4.0 mm (P = 0.002). Total RMS, LOA RMS, HOA RMS, PSF Strehl ratio and PSFw2 varied significantly between the studied groups (P < 0.001). Conclusions Far distance clinical image quality parameters measured by PWS aberrometer differed significantly according to the technology of the implanted lens. AT LISA Tri, SA60AT and PanOptix showed the highest values of far distance retinal image quality, while the lowest PSFw2 Strehl ratios were displayed by Miniwell, Mplus MF30 and Precizon Presbyopic.
Published: 2021

14. Risk of cerebrovascular accidents according to weather and pollution features

Author: Biondi-Zoccai, G, primary, Anticoli, S, additional, Pezzella, F, additional, Di Giosa, A, additional, Marchegiani, G, additional, Calcagno, S, additional, Di Pietro, R, additional, and Versaci, F, additional
Published: 2021
Full Text: View/download PDF

15. Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry

Author: Ntaios, G., Huisman, M. V., Diener, H. -C., Halperin, J. L., Teutsch, C., Marler, S., Gurusamy, V. K., Thompson, M., Lip, G. Y. H., Olshansky, B., Abban, D. W., Abdul, N., Abud, A. M., Adams, F., Addala, S., Adragao, P., Ageno, W., Aggarwal, R., Agosti, S., Agostoni, P., Aguilar, F., Linares, J. A., Aguinaga, L., Ahmed, J., Aiello, A., Ainsworth, P., Aiub, J. R., Al-Dallow, R., Alderson, L., Aldrete Velasco, J. A., Alexopoulos, D., Manterola, F. A., Aliyar, P., Alonso, D., Alves da Costa, F. A., Amado, J., Amara, W., Amelot, M., Amjadi, N., Ammirati, F., Andrade, M., Andrawis, N., Annoni, G., Ansalone, G., Ariani, M. K., Arias, J. C., Armero, S., Arora, C., Aslam, M. S., Asselman, M., Audouin, P., Augenbraun, C., Aydin, S., Ayryanova, I., Aziz, E., Backes, L. M., Badings, E., Bagni, E., Baker, S. H., Bala, R., Baldi, A., Bando, S., Banerjee, S., Bank, A., Esquivias, G. B., Barr, C., Bartlett, M., Kes, V. B., Baula, G., Behrens, S., Bell, A., Benedetti, R., Mazuecos, J. B., Benhalima, B., Bergler-Klein, J., Berneau, J. -B., Bernstein, R. A., Berrospi, P., Berti, S., Berz, A., Best, E., Bettencourt, P., Betzu, R., Bhagwat, R., Bhatta, L., Biscione, F., Bisignani, G., Black, T., Bloch, M. J., Bloom, S., Blumberg, E., Bo, M., Bohmer, E., Bollmann, A., Bongiorni, M. G., Boriani, G., Boswijk, D. J., Bott, J., Bottacchi, E., Kalan, M. B., Bradman, D., Brautigam, D., Breton, N., Brouwers, P. J. A. M., Browne, K., Cortada, J. B., Bruni, A., Brunschwig, C., Buathier, H., Buhl, A., Bullinga, J., Cabrera, J. W., Caccavo, A., Cai, S., Caine, S., Calo, L., Calvi, V., Sanchez, M. C., Candeias, R., Capuano, V., Capucci, A., Caputo, R., Rizo, T. C., Cardona, F., Carlos da Costa Darrieux, F., Duarte Vera, Y. C., Carolei, A., Carreno, S., Carvalho, P., Cary, S., Casu, G., Cavallini, C., Cayla, G., Celentano, A., Cha, T. -J., Cha, K. S., Chae, J. K., Chalamidas, K., Challappa, K., Chand, S. P., Chandrashekar, H., Chartier, L., Chatterjee, K., Chavez Ayala, C. A., Cheema, A., Chen, L., Chen, S. -A., Chen, J. H., Chiang, F. -T., Chiarella, F., Chih-Chan, L., Cho, Y. K., Choi, J. -I., Choi, D. J., Chouinard, G., Hoi-Fan Chow, D., Chrysos, D., Chumakova, G., Jose Roberto Chuquiure Valenzuela, E. J., Nica, N. C., Cislowski, D. J., Clay, A., Clifford, P., Cohen, A., Cohen, M., Cohen, S., Colivicchi, F., Collins, R., Colonna, P., Compton, S., Connolly, D., Conti, A., Buenostro, G. C., Coodley, G., Cooper, M., Coronel, J., Corso, G., Sales, J. C., Cottin, Y., Covalesky, J., Cracan, A., Crea, Filippo, Crean, P., Crenshaw, J., Cullen, T., Darius, H., Dary, P., Dascotte, O., Dauber, I., Davalos, V., Davies, R., Davis, G., Davy, J. -M., Dayer, M., De Biasio, M., De Bonis, S., De Caterina, R., De Franceschi, T., de Groot, J. R., De Horta, J., De La Briolle, A., Topete, G. D. L. P., Vicenzo de Paola, A. A., de Souza, W., de Veer, A., De Wolf, L., Decoulx, E., Deepak, S., Defaye, P., Del-Carpio Munoz, F., Brkljacic, D. D., Deumite, N. J., Di Legge, S., Diemberger, I., Dietz, D., Dionisio, P., Dong, Q., Rossi dos Santos, F., Dotcheva, E., Doukky, R., D'Souza, A., Dubrey, S., Ducrocq, X., Dupljakov, D., Duque, M., Dutta, D., Duvilla, N., Duygun, A., Dziewas, R., Eaton, C. B., Eaves, W., Ebels-Tuinbeek, L. A., Ehrlich, C., Eichinger-Hasenauer, S., Eisenberg, S. J., El Jabali, A., El Shahawy, M., Hernandes, M. E., Izal, A. E., Evonich, R., Evseeva, O., Ezhov, A., Fahmy, R., Fang, Q., Farsad, R., Fauchier, L., Favale, S., Fayard, M., Fedele, J. L., Fedele, F., Fedorishina, O., Fera, S. R., Gomes Ferreira, L. G., Ferreira, J., Ferri, C., Ferrier, A., Ferro, H., Finsen, A., First, B., Fischer, S., Fonseca, C., Almeida, L. F., Forman, S., Frandsen, B., French, W., Friedman, K., Friese, A., Fruntelata, A. G., Fujii, S., Fumagalli, S., Fundamenski, M., Furukawa, Y., Gabelmann, M., Gabra, N., Gadsboll, N., Galinier, M., Gammelgaard, A., Ganeshkumar, P., Gans, C., Quintana, A. G., Gartenlaub, O., Gaspardone, A., Genz, C., Georger, F., Georges, J. -L., Georgeson, S., Giedrimas, E., Gierba, M., Ortega, I. G., Gillespie, E., Giniger, A., Giudici, M. C., Gkotsis, A., Glotzer, T. V., Gmehling, J., Gniot, J., Goethals, P., Goldbarg, S., Goldberg, R., Goldmann, B., Golitsyn, S., Gomez, S., Mesa, J. G., Gonzalez, V. B., Gonzalez Hermosillo, J. A., Gonzalez Lopez, V. M., Gorka, H., Gornick, C., Gorog, D., Gottipaty, V., Goube, P., Goudevenos, I., Graham, B., Greer, G. S., Gremmler, U., Grena, P. G., Grond, M., Gronda, E., Gronefeld, G., Gu, X., Torres Torres, I. G., Guardigli, G., Guevara, C., Guignier, A., Gulizia, M., Gumbley, M., Gunther, A., Ha, A., Hahalis, G., Hakas, J., Hall, C., Han, B., Han, S., Hargrove, J., Hargroves, D., Harris, K. B., Haruna, T., Hayek, E., Healey, J., Hearne, S., Heffernan, M., Heggelund, G., Heijmeriks, J. A., Hemels, M., Hendriks, I., Henein, S., Her, S. -H., Hermany, P., Hernandez Del Rio, J. E., Higashino, Y., Hill, M., Hisadome, T., Hishida, E., Hoffer, E., Hoghton, M., Hong, K., Hong, S. K., Horbach, S., Horiuchi, M., Hou, Y., Hsing, J., Huang, C. -H., Huckins, D., Kathy, Hughe, Huizinga, A., Hulsman, E. L., Hung, K. -C., Hwang, G. -S., Ikpoh, M., Imberti, D., Ince, H., Indolfi, C., Inoue, S., Irles, D., Iseki, H., Israel, C. N., Iteld, B., Iyer, V., Jackson-Voyzey, E., Jaffrani, N., Jager, F., James, M., Jang, S. -W., Jaramillo, N., Jarmukli, N., Jeanfreau, R. J., Jenkins, R. D., Sanchez, C. J., Jimenez, J., Jobe, R., Joen-Jakobsen, T., Jones, N., Moura Jorge, J. C., Jouve, B., Jung, B. C., Jung, K. T., Jung, W., Kachkovskiy, M., Kafkala, K., Kalinina, L., Kallmunzer, B., Kamali, F., Kamo, T., Kampus, P., Kashou, H., Kastrup, A., Katsivas, A., Kaufman, E., Kawai, K., Kawajiri, K., Kazmierski, J. F., Keeling, P., Kerr Saraiva, J. F., Ketova, G., Khaira, A. S., Khripun, A., Kim, D. -I., Kim, Y. H., Kim, N. H., Kim, D. K., Kim, J. S., Kim, K. S., Kim, J. B., Kinova, E., Klein, A., Kmetzo, J. J., Kneller, G. L., Knezevic, A., Angela Koh, S. M., Koide, S., Kollias, A., Kooistra, J. A., Koons, J., Koschutnik, M., Kostis, W. J., Kovacic, D., Kowalczyk, J., Koziolova, N., Kraft, P., Kragten, J. A., Krantz, M., Krause, L., Krenning, B. J., Krikke, F., Kromhout, Z., Krysiak, W., Kumar, P., Kumler, T., Kuniss, M., Kuo, J. -Y., Kuppers, A., Kurrelmeyer, K., Kwak, C. H., Laboulle, B., Labovitz, A., Lai, W. T., Lam, A., Lam, Y. Y., Zanetti, F. L., Landau, C., Landini, G., Figueiredo, E. L., Larsen, T., Lavandier, K., Leblanc, J., Lee, M. H., Lee, C. -H., Lehman, J., Leitao, A., Lellouche, N., Lelonek, M., Lenarczyk, R., Lenderink, T., Gonzalez, S. L., Leong-Sit, P., Leschke, M., Ley, N., Li, Z., Li, X., Li, W., Lichy, C., Lieber, I., Limon Rodriguez, R. H., Lin, H., Liu, F., Liu, H., Esperon, G. L., Navarro, N. L., Lo, E., Lokshyn, S., Lopez, A., Lopez-Sendon, J. L., Lorga Filho, A. M., Lorraine, R. S., Luengas, C. A., Luke, R., Luo, M., Lupovitch, S., Lyrer, P., Ma, C., Ma, G., Madariaga, I., Maeno, K., Magnin, D., Maid, G., Mainigi, S. K., Makaritsis, K., Malhotra, R., Manning, R., Manolis, A., Manrique Hurtado, H. A., Mantas, I., Jattin, F. M., Maqueda, V., Marchionni, N., Ortuno, F. M., Santana, A. M., Martinez, J., Maskova, P., Hernandez, N. M., Matsuda, K., Maurer, T., Mauro, C., May, E., Mayer, N., Mcclure, J., Mccormack, T., Mcgarity, W., Mcintyre, H., Mclaurin, B., Medina Palomino, F. A., Melandri, F., Meno, H., Menzies, D., Mercader, M., Meyer, C., Meyer, B. J., Miarka, J., Mibach, F., Michalski, D., Michel, P., Chreih, R. M., Mikdadi, G., Mikus, M., Milicic, D., Militaru, C., Minaie, S., Minescu, B., Mintale, I., Mirault, T., Mirro, M. J., Mistry, D., Miu, N. V., Miyamoto, N., Moccetti, T., Mohammed, A., Nor, A. M., Mollerus, M., Molon, G., Mondillo, S., Moniz, P., Mont, L., Montagud, V., Montana, O., Monti, C., Moretti, L., Mori, K., Moriarty, A., Morka, J., Moschini, L., Moschos, N., Mugge, A., Mulhearn, T. J., Muresan, C., Muriago, M., Musial, W., Musser, C. W., Musumeci, F., Nageh, T., Nakagawa, H., Nakamura, Y., Nakayama, T., Nam, G. -B., Nanna, M., Natarajan, I., Nayak, H. M., Naydenov, S., Nazli, J., Nechita, A. C., Nechvatal, L., Negron, S. A., Neiman, J., Neuenschwander, F. C., Neves, D., Neykova, A., Miguel, R. N., Nijmeh, G., Nizov, A., Campos, R. N., Nossan, J., Novikova, T., Nowalany-Kozielska, E., Nsah, E., Nunez Fragoso, J. C., Nurgalieva, S., Nuyens, D., Nyvad, O., Odin de Los Rios Ibarra, M., O'Donnell, P., O'Donnell, M., Oh, S., Oh, Y. S., Oh, D., O'Hara, G., Oikonomou, K., Olivares, C., Oliver, R., Ruiz, R. O., Olympios, C., Anna, omaszuk-Kazberuk, Asensi, J. O., eena Padayattil, Jose, Padilla Padilla, F. G., Rios, V. P., Pajes, G., Pandey, A. S., Paparella, G., Paris, F., Park, H. W., Park, J. S., Parthenakis, F., Passamonti, E., Patel, R. J., Patel, J., Patel, M., Patrick, J., Jimenez, R. P., Paz, A., Pengo, V., Pentz, W., Perez, B., Perez Rios, A. M., Perez-Cabezas, A., Perlman, R., Persic, V., Perticone, F., Peters, T. K., Petkar, S., Pezo, L. F., Pflucke, C., Pham, D. N., Phillips, R. T., Phlaum, S., Pieters, D., Pineau, J., Pinter, A., Pinto, F., Pisters, R., Pivac, N., Pocanic, D., Podoleanu, C., Politano, A., Poljakovic, Z., Pollock, S., Garcea, J. P., Poppert, H., Porcu, M., Reino, A. P., Prasad, N., Precoma, D. B., Prelle, A., Prodafikas, J., Protasov, K., Pye, M., Qiu, Z., Quedillac, J. -M., Raev, D., Raffo Grado, C. A., Rahimi, S., Raisaro, A., Rama, B., Ramos, R., Ranieri, M., Raposo, N., Rashba, E., Rauch-Kroehnert, U., Reddy, R., Renda, G., Reza, S., Ria, L., Richter, D., Rickli, H., Rieker, W., Vera, T. R., Ritt, L. E., Roberts, D., Briones, I. R., Rodriguez Escudero, A. E., Pascual, C. R., Roman, M., Romeo, F., Ronner, E., Roux, J. -F., Rozkova, N., Rubacek, M., Rubalcava, F., Russo, A. M., Rutgers, M. P., Rybak, K., Said, S., Sakamoto, T., Salacata, A., Salem, A., Bodes, R. S., Saltzman, M. A., Salvioni, A., Vallejo, G. S., Fernandez, M. S., Saporito, W. F., Sarikonda, K., Sasaoka, T., Sati, H., Savelieva, I., Scala, P. -J., Schellinger, P., Scherr, C., Schmitz, L., Schmitz, K. -H., Schmitz, B., Schnabel, T., Schnupp, S., Schoeniger, P., Schon, N., Schwimmbeck, P., Seamark, C., Searles, G., Seidl, K. -H., Seidman, B., Sek, J., Sekaran, L., Serrati, C., Shah, N., Shah, V., Shah, A., Shah, S., Sharma, V. K., Shaw, L., Sheikh, K. H., Shimizu, N., Shimomura, H., Shin, D. -G., Shin, E. -S., Shite, J., Sibilio, G., Silver, F., Sime, I., Simmers, T. A., Singh, N., Siostrzonek, P., Smadja, D., Smith, D. W., Snitman, M., Filho, D. S., Soda, H., Sofley, C., Sokal, A., Oi Yan, Y. S., Sotolongo, R., Ferreira de Souza, O., Sparby, J. A., Spinar, J., Sprigings, D., Spyropoulos, A. C., Stakos, D., Steinwender, C., Stergiou, G., Stiell, I., Stoddard, M., Stoikov, A., Streb, W., Styliadis, I., Su, G., Su, X., Sudnik, W., Sukles, K., Sun, X., Swart, H., Szavits-Nossan, J., Taggeselle, J., Takagi, Y., Singh Takhar, A. P., Tamm, A., Tanaka, K., Tanawuttiwat, T., Tang, S., Tang, A., Tarsi, G., Tassinari, T., Tayal, A., Tayebjee, M., Berg, J. M. T., Tesloianu, D., The, S. H. K., Thomas, D., Timsit, S., Tobaru, T., Tomasik, A. R., Torosoff, M., Touze, E., Trendafilova, E., Tsai, W. K., Tse, H. F., Tsutsui, H., Tu, T. M., Tuininga, Y., Turakhia, M., Turk, S., Tcurner, W., Tveit, A., Tytus, R., Valadao, C., van Bergen, P. F. M. M., van de Borne, P., van den Berg, B. J., van der Zwaan, C., Van Eck, M., Vanacker, P., Vasilev, D., Vasilikos, V., Vasilyev, M., Veerareddy, S., Mino, M. V., Venkataraman, A., Verdecchia, P., Versaci, F., Vester, E. G., Vial, H., Victory, J., Villamil, A., Vincent, M., Vlastaris, A., Dahl, J. V., Vora, K., Vranian, R. B., Wakefield, P., Wang, N., Wang, M., Wang, X., Wang, F., Wang, T., Warner, A. L., Watanabe, K., Wei, J., Weimar, C., Weiner, S., Weinrich, R., Wen, M. -S., Wiemer, M., Wiggers, P., Wilke, A., Williams, D., Williams, M. L., Witzenbichler, B., Wong, B., Lawrence Wong, K. S., Wozakowska-Kaplon, B., Wu, S., Wu, R. C., Wunderlich, S., Wyatt, N., Wylie, J. J., Xu, Y., Xu, X., Yamanoue, H., Yamashita, T., Bryan Yan, P. Y., Yang, T., Yao, J., Yeh, K. -H., Yin, W. H., Yotov, Y., Zahn, R., Zarich, S., Zenin, S., Zeuthen, E. L., Zhang, H., Zhang, D., Zhang, X., Zhang, P., Zhang, J., Zhao, S. P., Zhao, Y., Zhao, Z., Zheng, Y., Zhou, J., Zimmermann, S., Zini, A., Zizzo, S., Zong, W., Zukerman, L. S., Crea F. (ORCID:0000-0001-9404-8846), Ntaios, G., Huisman, M. V., Diener, H. -C., Halperin, J. L., Teutsch, C., Marler, S., Gurusamy, V. K., Thompson, M., Lip, G. Y. H., Olshansky, B., Abban, D. W., Abdul, N., Abud, A. M., Adams, F., Addala, S., Adragao, P., Ageno, W., Aggarwal, R., Agosti, S., Agostoni, P., Aguilar, F., Linares, J. A., Aguinaga, L., Ahmed, J., Aiello, A., Ainsworth, P., Aiub, J. R., Al-Dallow, R., Alderson, L., Aldrete Velasco, J. A., Alexopoulos, D., Manterola, F. A., Aliyar, P., Alonso, D., Alves da Costa, F. A., Amado, J., Amara, W., Amelot, M., Amjadi, N., Ammirati, F., Andrade, M., Andrawis, N., Annoni, G., Ansalone, G., Ariani, M. K., Arias, J. C., Armero, S., Arora, C., Aslam, M. S., Asselman, M., Audouin, P., Augenbraun, C., Aydin, S., Ayryanova, I., Aziz, E., Backes, L. M., Badings, E., Bagni, E., Baker, S. H., Bala, R., Baldi, A., Bando, S., Banerjee, S., Bank, A., Esquivias, G. B., Barr, C., Bartlett, M., Kes, V. B., Baula, G., Behrens, S., Bell, A., Benedetti, R., Mazuecos, J. B., Benhalima, B., Bergler-Klein, J., Berneau, J. -B., Bernstein, R. A., Berrospi, P., Berti, S., Berz, A., Best, E., Bettencourt, P., Betzu, R., Bhagwat, R., Bhatta, L., Biscione, F., Bisignani, G., Black, T., Bloch, M. J., Bloom, S., Blumberg, E., Bo, M., Bohmer, E., Bollmann, A., Bongiorni, M. G., Boriani, G., Boswijk, D. J., Bott, J., Bottacchi, E., Kalan, M. B., Bradman, D., Brautigam, D., Breton, N., Brouwers, P. J. A. M., Browne, K., Cortada, J. B., Bruni, A., Brunschwig, C., Buathier, H., Buhl, A., Bullinga, J., Cabrera, J. W., Caccavo, A., Cai, S., Caine, S., Calo, L., Calvi, V., Sanchez, M. C., Candeias, R., Capuano, V., Capucci, A., Caputo, R., Rizo, T. C., Cardona, F., Carlos da Costa Darrieux, F., Duarte Vera, Y. C., Carolei, A., Carreno, S., Carvalho, P., Cary, S., Casu, G., Cavallini, C., Cayla, G., Celentano, A., Cha, T. -J., Cha, K. S., Chae, J. K., Chalamidas, K., Challappa, K., Chand, S. P., Chandrashekar, H., Chartier, L., Chatterjee, K., Chavez Ayala, C. A., Cheema, A., Chen, L., Chen, S. -A., Chen, J. H., Chiang, F. -T., Chiarella, F., Chih-Chan, L., Cho, Y. K., Choi, J. -I., Choi, D. J., Chouinard, G., Hoi-Fan Chow, D., Chrysos, D., Chumakova, G., Jose Roberto Chuquiure Valenzuela, E. J., Nica, N. C., Cislowski, D. J., Clay, A., Clifford, P., Cohen, A., Cohen, M., Cohen, S., Colivicchi, F., Collins, R., Colonna, P., Compton, S., Connolly, D., Conti, A., Buenostro, G. C., Coodley, G., Cooper, M., Coronel, J., Corso, G., Sales, J. C., Cottin, Y., Covalesky, J., Cracan, A., Crea, Filippo, Crean, P., Crenshaw, J., Cullen, T., Darius, H., Dary, P., Dascotte, O., Dauber, I., Davalos, V., Davies, R., Davis, G., Davy, J. -M., Dayer, M., De Biasio, M., De Bonis, S., De Caterina, R., De Franceschi, T., de Groot, J. R., De Horta, J., De La Briolle, A., Topete, G. D. L. P., Vicenzo de Paola, A. A., de Souza, W., de Veer, A., De Wolf, L., Decoulx, E., Deepak, S., Defaye, P., Del-Carpio Munoz, F., Brkljacic, D. D., Deumite, N. J., Di Legge, S., Diemberger, I., Dietz, D., Dionisio, P., Dong, Q., Rossi dos Santos, F., Dotcheva, E., Doukky, R., D'Souza, A., Dubrey, S., Ducrocq, X., Dupljakov, D., Duque, M., Dutta, D., Duvilla, N., Duygun, A., Dziewas, R., Eaton, C. B., Eaves, W., Ebels-Tuinbeek, L. A., Ehrlich, C., Eichinger-Hasenauer, S., Eisenberg, S. J., El Jabali, A., El Shahawy, M., Hernandes, M. E., Izal, A. E., Evonich, R., Evseeva, O., Ezhov, A., Fahmy, R., Fang, Q., Farsad, R., Fauchier, L., Favale, S., Fayard, M., Fedele, J. L., Fedele, F., Fedorishina, O., Fera, S. R., Gomes Ferreira, L. G., Ferreira, J., Ferri, C., Ferrier, A., Ferro, H., Finsen, A., First, B., Fischer, S., Fonseca, C., Almeida, L. F., Forman, S., Frandsen, B., French, W., Friedman, K., Friese, A., Fruntelata, A. G., Fujii, S., Fumagalli, S., Fundamenski, M., Furukawa, Y., Gabelmann, M., Gabra, N., Gadsboll, N., Galinier, M., Gammelgaard, A., Ganeshkumar, P., Gans, C., Quintana, A. G., Gartenlaub, O., Gaspardone, A., Genz, C., Georger, F., Georges, J. -L., Georgeson, S., Giedrimas, E., Gierba, M., Ortega, I. G., Gillespie, E., Giniger, A., Giudici, M. C., Gkotsis, A., Glotzer, T. V., Gmehling, J., Gniot, J., Goethals, P., Goldbarg, S., Goldberg, R., Goldmann, B., Golitsyn, S., Gomez, S., Mesa, J. G., Gonzalez, V. B., Gonzalez Hermosillo, J. A., Gonzalez Lopez, V. M., Gorka, H., Gornick, C., Gorog, D., Gottipaty, V., Goube, P., Goudevenos, I., Graham, B., Greer, G. S., Gremmler, U., Grena, P. G., Grond, M., Gronda, E., Gronefeld, G., Gu, X., Torres Torres, I. G., Guardigli, G., Guevara, C., Guignier, A., Gulizia, M., Gumbley, M., Gunther, A., Ha, A., Hahalis, G., Hakas, J., Hall, C., Han, B., Han, S., Hargrove, J., Hargroves, D., Harris, K. B., Haruna, T., Hayek, E., Healey, J., Hearne, S., Heffernan, M., Heggelund, G., Heijmeriks, J. A., Hemels, M., Hendriks, I., Henein, S., Her, S. -H., Hermany, P., Hernandez Del Rio, J. E., Higashino, Y., Hill, M., Hisadome, T., Hishida, E., Hoffer, E., Hoghton, M., Hong, K., Hong, S. K., Horbach, S., Horiuchi, M., Hou, Y., Hsing, J., Huang, C. -H., Huckins, D., Kathy, Hughe, Huizinga, A., Hulsman, E. L., Hung, K. -C., Hwang, G. -S., Ikpoh, M., Imberti, D., Ince, H., Indolfi, C., Inoue, S., Irles, D., Iseki, H., Israel, C. N., Iteld, B., Iyer, V., Jackson-Voyzey, E., Jaffrani, N., Jager, F., James, M., Jang, S. -W., Jaramillo, N., Jarmukli, N., Jeanfreau, R. J., Jenkins, R. D., Sanchez, C. J., Jimenez, J., Jobe, R., Joen-Jakobsen, T., Jones, N., Moura Jorge, J. C., Jouve, B., Jung, B. C., Jung, K. T., Jung, W., Kachkovskiy, M., Kafkala, K., Kalinina, L., Kallmunzer, B., Kamali, F., Kamo, T., Kampus, P., Kashou, H., Kastrup, A., Katsivas, A., Kaufman, E., Kawai, K., Kawajiri, K., Kazmierski, J. F., Keeling, P., Kerr Saraiva, J. F., Ketova, G., Khaira, A. S., Khripun, A., Kim, D. -I., Kim, Y. H., Kim, N. H., Kim, D. K., Kim, J. S., Kim, K. S., Kim, J. B., Kinova, E., Klein, A., Kmetzo, J. J., Kneller, G. L., Knezevic, A., Angela Koh, S. M., Koide, S., Kollias, A., Kooistra, J. A., Koons, J., Koschutnik, M., Kostis, W. J., Kovacic, D., Kowalczyk, J., Koziolova, N., Kraft, P., Kragten, J. A., Krantz, M., Krause, L., Krenning, B. J., Krikke, F., Kromhout, Z., Krysiak, W., Kumar, P., Kumler, T., Kuniss, M., Kuo, J. -Y., Kuppers, A., Kurrelmeyer, K., Kwak, C. H., Laboulle, B., Labovitz, A., Lai, W. T., Lam, A., Lam, Y. Y., Zanetti, F. L., Landau, C., Landini, G., Figueiredo, E. L., Larsen, T., Lavandier, K., Leblanc, J., Lee, M. H., Lee, C. -H., Lehman, J., Leitao, A., Lellouche, N., Lelonek, M., Lenarczyk, R., Lenderink, T., Gonzalez, S. L., Leong-Sit, P., Leschke, M., Ley, N., Li, Z., Li, X., Li, W., Lichy, C., Lieber, I., Limon Rodriguez, R. H., Lin, H., Liu, F., Liu, H., Esperon, G. L., Navarro, N. L., Lo, E., Lokshyn, S., Lopez, A., Lopez-Sendon, J. L., Lorga Filho, A. M., Lorraine, R. S., Luengas, C. A., Luke, R., Luo, M., Lupovitch, S., Lyrer, P., Ma, C., Ma, G., Madariaga, I., Maeno, K., Magnin, D., Maid, G., Mainigi, S. K., Makaritsis, K., Malhotra, R., Manning, R., Manolis, A., Manrique Hurtado, H. A., Mantas, I., Jattin, F. M., Maqueda, V., Marchionni, N., Ortuno, F. M., Santana, A. M., Martinez, J., Maskova, P., Hernandez, N. M., Matsuda, K., Maurer, T., Mauro, C., May, E., Mayer, N., Mcclure, J., Mccormack, T., Mcgarity, W., Mcintyre, H., Mclaurin, B., Medina Palomino, F. A., Melandri, F., Meno, H., Menzies, D., Mercader, M., Meyer, C., Meyer, B. J., Miarka, J., Mibach, F., Michalski, D., Michel, P., Chreih, R. M., Mikdadi, G., Mikus, M., Milicic, D., Militaru, C., Minaie, S., Minescu, B., Mintale, I., Mirault, T., Mirro, M. J., Mistry, D., Miu, N. V., Miyamoto, N., Moccetti, T., Mohammed, A., Nor, A. M., Mollerus, M., Molon, G., Mondillo, S., Moniz, P., Mont, L., Montagud, V., Montana, O., Monti, C., Moretti, L., Mori, K., Moriarty, A., Morka, J., Moschini, L., Moschos, N., Mugge, A., Mulhearn, T. J., Muresan, C., Muriago, M., Musial, W., Musser, C. W., Musumeci, F., Nageh, T., Nakagawa, H., Nakamura, Y., Nakayama, T., Nam, G. -B., Nanna, M., Natarajan, I., Nayak, H. M., Naydenov, S., Nazli, J., Nechita, A. C., Nechvatal, L., Negron, S. A., Neiman, J., Neuenschwander, F. C., Neves, D., Neykova, A., Miguel, R. N., Nijmeh, G., Nizov, A., Campos, R. N., Nossan, J., Novikova, T., Nowalany-Kozielska, E., Nsah, E., Nunez Fragoso, J. C., Nurgalieva, S., Nuyens, D., Nyvad, O., Odin de Los Rios Ibarra, M., O'Donnell, P., O'Donnell, M., Oh, S., Oh, Y. S., Oh, D., O'Hara, G., Oikonomou, K., Olivares, C., Oliver, R., Ruiz, R. O., Olympios, C., Anna, omaszuk-Kazberuk, Asensi, J. O., eena Padayattil, Jose, Padilla Padilla, F. G., Rios, V. P., Pajes, G., Pandey, A. S., Paparella, G., Paris, F., Park, H. W., Park, J. S., Parthenakis, F., Passamonti, E., Patel, R. J., Patel, J., Patel, M., Patrick, J., Jimenez, R. P., Paz, A., Pengo, V., Pentz, W., Perez, B., Perez Rios, A. M., Perez-Cabezas, A., Perlman, R., Persic, V., Perticone, F., Peters, T. K., Petkar, S., Pezo, L. F., Pflucke, C., Pham, D. N., Phillips, R. T., Phlaum, S., Pieters, D., Pineau, J., Pinter, A., Pinto, F., Pisters, R., Pivac, N., Pocanic, D., Podoleanu, C., Politano, A., Poljakovic, Z., Pollock, S., Garcea, J. P., Poppert, H., Porcu, M., Reino, A. P., Prasad, N., Precoma, D. B., Prelle, A., Prodafikas, J., Protasov, K., Pye, M., Qiu, Z., Quedillac, J. -M., Raev, D., Raffo Grado, C. A., Rahimi, S., Raisaro, A., Rama, B., Ramos, R., Ranieri, M., Raposo, N., Rashba, E., Rauch-Kroehnert, U., Reddy, R., Renda, G., Reza, S., Ria, L., Richter, D., Rickli, H., Rieker, W., Vera, T. R., Ritt, L. E., Roberts, D., Briones, I. R., Rodriguez Escudero, A. E., Pascual, C. R., Roman, M., Romeo, F., Ronner, E., Roux, J. -F., Rozkova, N., Rubacek, M., Rubalcava, F., Russo, A. M., Rutgers, M. P., Rybak, K., Said, S., Sakamoto, T., Salacata, A., Salem, A., Bodes, R. S., Saltzman, M. A., Salvioni, A., Vallejo, G. S., Fernandez, M. S., Saporito, W. F., Sarikonda, K., Sasaoka, T., Sati, H., Savelieva, I., Scala, P. -J., Schellinger, P., Scherr, C., Schmitz, L., Schmitz, K. -H., Schmitz, B., Schnabel, T., Schnupp, S., Schoeniger, P., Schon, N., Schwimmbeck, P., Seamark, C., Searles, G., Seidl, K. -H., Seidman, B., Sek, J., Sekaran, L., Serrati, C., Shah, N., Shah, V., Shah, A., Shah, S., Sharma, V. K., Shaw, L., Sheikh, K. H., Shimizu, N., Shimomura, H., Shin, D. -G., Shin, E. -S., Shite, J., Sibilio, G., Silver, F., Sime, I., Simmers, T. A., Singh, N., Siostrzonek, P., Smadja, D., Smith, D. W., Snitman, M., Filho, D. S., Soda, H., Sofley, C., Sokal, A., Oi Yan, Y. S., Sotolongo, R., Ferreira de Souza, O., Sparby, J. A., Spinar, J., Sprigings, D., Spyropoulos, A. C., Stakos, D., Steinwender, C., Stergiou, G., Stiell, I., Stoddard, M., Stoikov, A., Streb, W., Styliadis, I., Su, G., Su, X., Sudnik, W., Sukles, K., Sun, X., Swart, H., Szavits-Nossan, J., Taggeselle, J., Takagi, Y., Singh Takhar, A. P., Tamm, A., Tanaka, K., Tanawuttiwat, T., Tang, S., Tang, A., Tarsi, G., Tassinari, T., Tayal, A., Tayebjee, M., Berg, J. M. T., Tesloianu, D., The, S. H. K., Thomas, D., Timsit, S., Tobaru, T., Tomasik, A. R., Torosoff, M., Touze, E., Trendafilova, E., Tsai, W. K., Tse, H. F., Tsutsui, H., Tu, T. M., Tuininga, Y., Turakhia, M., Turk, S., Tcurner, W., Tveit, A., Tytus, R., Valadao, C., van Bergen, P. F. M. M., van de Borne, P., van den Berg, B. J., van der Zwaan, C., Van Eck, M., Vanacker, P., Vasilev, D., Vasilikos, V., Vasilyev, M., Veerareddy, S., Mino, M. V., Venkataraman, A., Verdecchia, P., Versaci, F., Vester, E. G., Vial, H., Victory, J., Villamil, A., Vincent, M., Vlastaris, A., Dahl, J. V., Vora, K., Vranian, R. B., Wakefield, P., Wang, N., Wang, M., Wang, X., Wang, F., Wang, T., Warner, A. L., Watanabe, K., Wei, J., Weimar, C., Weiner, S., Weinrich, R., Wen, M. -S., Wiemer, M., Wiggers, P., Wilke, A., Williams, D., Williams, M. L., Witzenbichler, B., Wong, B., Lawrence Wong, K. S., Wozakowska-Kaplon, B., Wu, S., Wu, R. C., Wunderlich, S., Wyatt, N., Wylie, J. J., Xu, Y., Xu, X., Yamanoue, H., Yamashita, T., Bryan Yan, P. Y., Yang, T., Yao, J., Yeh, K. -H., Yin, W. H., Yotov, Y., Zahn, R., Zarich, S., Zenin, S., Zeuthen, E. L., Zhang, H., Zhang, D., Zhang, X., Zhang, P., Zhang, J., Zhao, S. P., Zhao, Y., Zhao, Z., Zheng, Y., Zhou, J., Zimmermann, S., Zini, A., Zizzo, S., Zong, W., Zukerman, L. S., and Crea F. (ORCID:0000-0001-9404-8846)
Abstract: Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007.
Published: 2021

16. Right ventricular infarction: can we still use old tricks?

Author: Tadic, M, Cuspidi, C, Versaci, F, Calcagno, S, Marijana Tadic, Cesare Cuspidi, Francesco Versaci, Simone Calcagno, Tadic, M, Cuspidi, C, Versaci, F, Calcagno, S, Marijana Tadic, Cesare Cuspidi, Francesco Versaci, and Simone Calcagno
Published: 2021

17. NLRP3 Inflammasome: A New Promising Therapeutic Target to Treat Heart Failure

Author: Del Buono, Marco Giuseppe, Crea, Filippo, Versaci, F., Biondi-Zoccai, G., Del Buono M. G., Crea F. (ORCID:0000-0001-9404-8846), Del Buono, Marco Giuseppe, Crea, Filippo, Versaci, F., Biondi-Zoccai, G., Del Buono M. G., and Crea F. (ORCID:0000-0001-9404-8846)
Abstract: N/A
Published: 2021

18. Interplay between COVID-19, pollution, and weather features on changes in the incidence of acute coronary syndromes in early 2020

Author: Versaci, F., Gaspardone, A., Danesi, A., Ferranti, F., Mancone, M., Mariano, E., Rotolo, F. L., Musto, C., Proietti, I., Berni, A., Trani, Carlo, Sergi, S. C., Speciale, G., Tanzilli, G., Tomai, Fabrizio, Di Giosa, A., Marchegiani, G., Romagnoli, Elisa, Cavarretta, E., Carnevale, R., Frati, G., Biondi-Zoccai, G., Trani C. (ORCID:0000-0001-9777-013X), Tomai F., Romagnoli E., Versaci, F., Gaspardone, A., Danesi, A., Ferranti, F., Mancone, M., Mariano, E., Rotolo, F. L., Musto, C., Proietti, I., Berni, A., Trani, Carlo, Sergi, S. C., Speciale, G., Tanzilli, G., Tomai, Fabrizio, Di Giosa, A., Marchegiani, G., Romagnoli, Elisa, Cavarretta, E., Carnevale, R., Frati, G., Biondi-Zoccai, G., Trani C. (ORCID:0000-0001-9777-013X), Tomai F., and Romagnoli E.
Abstract: Background: Coronavirus disease 2019 (COVID-19) has caused an unprecedented change in the apparent epidemiology of acute coronary syndromes (ACS). However, the interplay between this disease, changes in pollution, climate, and aversion to activation of emergency medical services represents a challenging conundrum. We aimed at appraising the impact of COVID-19, weather, and environment features on the occurrence of ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) in a large Italian region and metropolitan area. Methods and results: Italy was hit early on by COVID-19, such that state of emergency was declared on January 31, 2020, and national lockdown implemented on March 9, 2020, mainly because the accrual of cases in Northern Italy. In order to appraise the independent contribution on changes in STEMI and NSTEMI daily rates of COVID-19, climate and pollution, we collected data on these clinical events from tertiary care cardiovascular centers in the Lazio region and Rome metropolitan area. Multilevel Poisson modeling was used to appraise unadjusted and adjusted effect estimates for the daily incidence of STEMI and NSTEMI cases. The sample included 1448 STEMI and 2040 NSTEMI, with a total of 2882 PCI spanning 6 months. Significant reductions in STEMI and NSTEMI were evident already in early February 2020 (all p<0.05), concomitantly with COVID-19 spread and institution of national countermeasures. Changes in STEMI and NSTEMI were inversely associated with daily COVID-19 tests, cases, and/or death (p<0.05). In addition, STEMI and NSTEMI incidences were associated with daily NO2, PM10, and O3 concentrations, as well as temperature (p<0.05). Multi-stage and multiply adjusted models highlighted that reductions in STEMI were significantly associated with COVID-19 data (p<0.001), whereas changes in NSTEMI were significantly associated with both NO2 and COVID-19 data (both p<0.001). Conclusions: Reductions in STEMI
Published: 2021

19. Impact of environmental pollution and climate changes on the incidence of ST-elevation myocardial infarction

Author: Biondi-Zoccai, G, primary, Frati, G, additional, Gaspardone, A, additional, Mariano, E, additional, Di Giosa, A, additional, Bolignano, A, additional, Dei Giudici, A, additional, Calcagno, S, additional, Scappaticci, M, additional, Sciarretta, S, additional, Valenti, V, additional, Peruzzi, M, additional, Federici, M, additional, Romeo, F, additional, and Versaci, F, additional
Published: 2020
Full Text: View/download PDF

20. A comparison of coronary artery stenting with angioplasty for isolated stenosis of the proximal left anterior descending coronary artery: five year clinical follow up

Author: Versaci, F, Gaspardone, A, Tomai, F, Proietti, I, Ghini, A S, Altamura, L, Andò, G, Crea, F, Gioffrè, P A, and Chiariello, L
Published: 2004

21. Left anterior descending and circumflex coronary artery spasm after right coronary artery stent implantation

Author: Versaci, F, Gaspardone, A, and Proietti, I
Published: 2002

22. Exercise induced myocardial ischaemia does not cause increase in C-reactive protein concentration

Author: GASPARDONE, A, PERINO, M, GHINI, A S, TOMAI, F, VERSACI, F, PROIETTI, I, and CREA, F
Published: 2000

23. Missed opportunities in cardiac arrest. The promise of 24/7 ongoing on-site interventional cardiologist availability

Author: Versaci, F, Biondi-Zoccai, G, Sciarretta, S, Frati, G, and Romeo, F
Subjects: Cardiologists, humans, cardiologists, heart arrest, Humans, Settore MED/06, Heart Arrest
Published: 2018

24. P6373Two generations of bioresorbable vascular Scaffold in comparison: clinical, angiographic and computed tomography follow-up

Author: Vizzari, G, primary, Ando', G, additional, Trivisonno, A, additional, Biondi Zoccai, G, additional, Gatto, L, additional, Prati, F, additional, Romeo, F, additional, and Versaci, F, additional
Published: 2018
Full Text: View/download PDF

25. Clinical impact of suboptimal stenting and residual intrastent plaque/thrombus protrusion in patients with acute coronary syndrome: the CLI-OPCI ACS substudy

Author: Prati, F, Romagnoli, E, Gatto, L, La Manna, A, Versaci, F, Fabbiocchi, F, Di Giorgio, A, Marco, V, Ramazzotti, V, Di Vito, L, Trani, C, Porto, I, Boi, A, Gavazzi, L, and Mintz, G
Subjects: Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Published: 2016

26. Impact of coronary revascularization on the clinical and scintigraphic outlook of patients with myocardial ischemia

Author: Nudi, F., Procaccini, E., Versaci, F., Giordano, Alessandro, Pinto, A., Neri, G., Frati, G., Schillaci, O., Nudi, A., Tomai, Fabrizio, Biondi-Zoccai, G., Giordano A. (ORCID:0000-0002-6978-0880), Tomai F., Nudi, F., Procaccini, E., Versaci, F., Giordano, Alessandro, Pinto, A., Neri, G., Frati, G., Schillaci, O., Nudi, A., Tomai, Fabrizio, Biondi-Zoccai, G., Giordano A. (ORCID:0000-0002-6978-0880), and Tomai F.
Abstract: Aims: The impact of coronary revascularization on outcomes and ischemic burden among patients with objective proof of ischemia is not yet established. We appraised the impact of revascularization on outcomes and residual ischemia in patients with objective evidence of ischemia at myocardial perfusion scintigraphy (MPS). Methods: We queried our database for stable patients with myocardial ischemia at MPS, excluding those with prior myocardial infarction, systolic dysfunction, or cardiomyopathy. The impact of revascularization (defined as revascularization as first follow-up event) on outcomes and changes in myocardial ischemia at repeat MPS was appraised with propensity-matched analyses. Results: From 6195 patients, propensity matching yielded 1262 pairs of patients undergoing revascularization versus not undergoing revascularization. After 35.2±23.9 months, revascularization was associated with lower risks of cardiac death [2 (0.2%) versus 10 (0.8%) in those not revascularized, PU0.038] and of the composite of cardiac death or myocardial infarction [17 (1.3%) versus 37 (2.9%), PU0.007]. In addition, revascularization was associated with a higher rate of improvement in ischemia degree after 28.1±20.7 months of follow-up (P<0.001), with 257 (69.3%) patients with moderate or severe ischemia at baseline MPS improving after revascularization versus 136 (42.0%) in the nonrevascularization group. Conversely, revascularization did not prove impactful on follow-up MPS in patients with only minimal or mild ischemia at baseline MPS (P<0.001). Conclusion: In a large series of patients with objective evidence of myocardial ischemia at MPS, especially when moderate or severe, revascularization was associated with a better clinical prognosis and a lower ischemic burden at repeat MPS.
Published: 2017

27. PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS TREATED WITH ORAL ANTICOAGULANT THERAPY: BASELINE CLINICAL CHARACTERISTICS OF THE PERSEO REGISTRY

Author: Sciahbasi, A, Gargiulo, G, Giacoppo, D, Talarico, G, Calabrò, P, Zilio, F, De Rosa, S, Talanas, G, Tebaldi, M, Andò, G, Rigattieri, S, Misuraca, L, Cortese, B, Musuraca, G, Lucci, V, Guiducci, V, Renda, G, Zezza, L, Versaci, F, Giannico, M, Caruso, M, Fischetti, D, Colletta, M, Santarelli, A, Larosa, C, Iannone, A, Esposito, G, Tarantini, G, Musumeci, G, and Rubboli, A
Published: 2024
Full Text: View/download PDF

28. AuroraScience Project. Report on the First Phase. July 31st, 2009 - April 22th, 2011

Author: Beccara, S, Alfieri, R, Artico, F, Bilardi, G, Brambilla, M, Boso, F, Cappelleri, V, Cestaro, A, Cilia, E, Cristoforetti, M, Dalla Brida, M, D’Antonio, M, Di Renzo, F, Faccioli, P, Fantozzi, C, Fontana, P, Gargano, C, Grossi, M, Illarionov, A, Leonardi, R, Leidemann, W, Milani, E, Moser, C, Onofri, E, Orlandini, G, Pederiva, F, Peruch, F, Peserico, E, Pietracaprina, A, Pivanti, M, Pozzati, F, Pucci, G, Richter, A, Sega, M, Schifano, S, Schimd, S, Scorzato, L, Simma, H, Skrbic, T, Tagliavini, E, Traini, M, Tripiccione, R, Velasco, V, Versaci, F, Yuan, L, Zago, N., DESTRI, CLAUDIO, MARCHESINI, GIUSEPPE, RAPUANO, FEDERICO, Beccara, S, Alfieri, R, Artico, F, Bilardi, G, Brambilla, M, Boso, F, Cappelleri, V, Cestaro, A, Cilia, E, Cristoforetti, M, Dalla Brida, M, D’Antonio, M, Di Renzo, F, Destri, C, Faccioli, P, Fantozzi, C, Fontana, P, Gargano, C, Grossi, M, Illarionov, A, Leonardi, R, Leidemann, W, Marchesini, G, Milani, E, Moser, C, Onofri, E, Orlandini, G, Pederiva, F, Peruch, F, Peserico, E, Pietracaprina, A, Pivanti, M, Pozzati, F, Pucci, G, Rapuano, F, Richter, A, Sega, M, Schifano, S, Schimd, S, Scorzato, L, Simma, H, Skrbic, T, Tagliavini, E, Traini, M, Tripiccione, R, Velasco, V, Versaci, F, Yuan, L, and Zago, N
Subjects: aurorascience
Published: 2012

29. Percutaneous coronary intervention driven by combined use of intracoronary anatomy and physiology: Towards a tailored therapy for coronary artery disease

Author: Vizzari, G, Di Giorgio, A, Saporito, F, Trio, O, Versaci, F, and Andò, G
Subjects: Optical coherence tomography (OCT), PCI, Percutaneous coronary revascularization, Fractional flow reserve (FFR), Multimodality coronary imaging, Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Published: 2015

30. Clinical Impact of OCT Findings During PCI: The CLI-OPCI II Study

Author: Prati, F, Romagnoli, E, Burzotta, F, Limbruno, U, Gatto, L, La Manna, A, Versaci, F, Marco, V, Di Vito, L, Imola, F, Paoletti, G, Trani, C, Tamburino, Corrado, Tavazzi, L, and Mintz, G. S.
Subjects: optical coherence tomography, percutaneous coronary intervention, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, clinical outcome, cardiovascular diseases, registry
Abstract: ObjectivesThe goal of this study was to assess the clinical impact of optical coherence tomography (OCT) findings during percutaneous coronary intervention (PCI).BackgroundOCT provides unprecedented high-definition visualization of plaque/stent structures during PCI; however, the impact of OCT findings on outcome remains undefined.MethodsIn the context of the multicenter CLI-OPCI (Centro per la Lotta contro l’Infarto–Optimisation of Percutaneous Coronary Intervention) registry, we retrospectively analyzed patients undergoing end-procedural OCT assessment and compared the findings with clinical outcomes.ResultsA total of 1,002 lesions (832 patients) were assessed. Appropriate OCT assessment was obtained in 98.2% of cases and revealed suboptimal stent implantation in 31.0% of lesions, with increased incidence in patients experiencing major adverse cardiac events (MACE) during follow-up (59.2% vs. 26.9%; p < 0.001). In particular, in-stent minimum lumen area 200 μm at the distal stent edge (HR: 2.54; p = 0.004), and reference lumen area 200 μm (HR: 1.15; p = 0.52), intrastent plaque/thrombus protrusion >500 μm (HR: 1.00; p = 0.99), and dissection >200 μm at the proximal stent edge (HR: 0.83; p = 0.65) were not associated with worse outcomes. Using multivariable Cox hazard analysis, the presence of at least 1 significant criterion for suboptimal OCT stent deployment was confirmed as an independent predictor of MACE (HR: 3.53; 95% confidence interval: 2.2 to 5.8; p < 0.001).ConclusionsSuboptimal stent deployment defined according to specific quantitative OCT criteria was associated with an increased risk of MACE during follow-up.
Published: 2015

31. One-year outcome from an all-comers population of patients with ST-segment elevation myocardial infarction treated with biolimus-eluting stent with biodegradable polymer

Author: Tomai, F, De Luca, L, Altamura, L, Versaci, F, Pennacchi, M, Proietti, I, Ghini, A, Corvo, P, De Persio, G, Petrolini, A, Tommasino, A, and Sardella, G
Subjects: Male, Time Factors, Myocardial Infarction, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Kaplan-Meier Estimate, Prosthesis Design, ST-elevation myocardial infarction, biodegradable polymer, biolimus-eluting stent, real-world registry, Disease-Free Survival, Percutaneous Coronary Intervention, Recurrence, Risk Factors, Humans, Prospective Studies, Registries, Aged, Sirolimus, Cardiovascular Agents, Drug-Eluting Stents, Middle Aged, Treatment Outcome, Italy, Female
Abstract: To evaluate the performance of biolimus-eluting stent (BES) in patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) in a real world clinical scenario.Randomized studies suggest that the BES with biodegradable polymer is more effective and safe than early generation coronary stents in patients with STEMI.We included all consecutive STEMI patients undergoing PCI in this prospective, multicenter registry. The primary endpoint of the study was the rate of major adverse cardiac events (MACE), a composite of cardiac death, recurrent myocardial infarction and ischemia-driven target vessel revascularization at 1-year follow-up.Between June and December 2012 we enrolled 311 STEMI patients. The primary endpoint occurred in 3.2% (95% confidence interval: 1.6-5.8) of patients: cardiac death, re-infarction, and ischemia-driven TVR occurred in 2.3%, 1.3%, and 0.6% of patients, respectively. One-year MACE-free survival was 96.8% ± 1.0%.In a real-world cohort of STEMI patients undergoing PCI, the use of BES is associated with good 1-year clinical outcome. These results confirm and expand previous findings showing the efficacy and safety of BES in the setting of randomized trials.
Published: 2014

32. ORA1 iMmunosuppressive therapy to prevent in-Stent rEstenosiS (RAMSES) cooperation: A patient-level meta-analysis of randomized trials

Author: Cassese, S, de Luca, G, Ribichini, F, Cernigliaro, C, Sansa, M, Versaci, F, Proietti, I, Stankovic, G, Stojkovic, S, Fernandez-Pereira, C, Tomai, F, Vassanelli, C, Antoniucci, D, Serruys, PWJC (Patrick), Kastrati, A, Rodriguez, AE, and Cardiology
Subjects: stomatognathic diseases, education, digestive, oral, and skin physiology
Abstract: Objective: The role of oral immunosuppressive therapy (OIT) to prevent restenosis after percutaneous coronary intervention (PCI) and stenting is still controversial. This study evaluates the impact of oral administration of prednisone or sirolimus to prevent restenosis. Methods: We conducted a meta-analysis of trials in which PCI-patients were randomized to bare metal stents (BMS) plus OIT (BMS + OIT group) versus BMS or drug-eluting stents alone (BMS/DES group). Primary endpoints were target lesion revascularization and death/myocardial infarction (MI). Secondary endpoints were death, MI, stent thrombosis and in-stent late lumen loss. Hazard ratio and weighted geometric mean difference [95% confidence intervals] served as summary statistics. Results: Individual data of seven trials (1246 patients [BMS + OIT, n = 608 versus BMS/DES, n = 638] with 1456 coronary lesions) were merged. At a median follow-up of 360 days, BMS + OIT versus BMS/DES significantly reduced the risk of revascularization (0.49 [0.24-0.98], P = 0.04). In particular, BMS + OIT reduced the risk of revascularization (0.38 [0.21-0.67], P < 0.001) and late lumen loss (-0.39 mm [-0.67, -0.11], P < 0.001) as compared with BMS alone. BMS + OIT versus BMS/DES showed a similar risk of death/MI (0.67 [0.29-1.53], P = 0.34), death (0.82 [0.25-2.69], P = 0.71), MI (0.58 [0.24-1.39], P = 0.22) and stent thrombosis (0.43 [0.10-1.87], P = 0.26). Conclusion: In patients undergoing PCI the use of BMS and oral immunosuppressive therapy reduces the risk of revascularization as compared with BMS alone but not as compared with DES alone, while these therapies display a similar risk of death/MI. The advantage of adding oral immunosuppressive therapy to BMS is due to a lower risk of restenosis as compared with BMS alone. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
Published: 2014

33. [ The new 2010 Ghent criteria for the indication to surgical treatment of patients affected by Marfan syndrome. Experience of a single cardiac surgery center]

Author: Grego, S, Nardi, P, Gislao, V, Nicolò, F, D'Annolfo, A, Marcucci, R, Bovio, E, Versaci, F, and Chiariello, L
Subjects: Settore MED/23 - Chirurgia Cardiaca
Published: 2013

34. Simultaneous Hybrid Revascularization by Carotid Stenting and Coronary Artery Bypass Grafting – The SHARP Study

Author: Chiariello, L, Nardi, P, and Versaci, F
Subjects: cardiovascular system, Settore MED/23 - Chirurgia Cardiaca, cardiovascular diseases
Published: 2012
Full Text: View/download PDF

35. Mid-term results of (s)imultaneous (h)ybrid rev(a)scularization by ca(r)otid stenting and coronary artery by(p)ass grafting (sharp) protocol

Author: Nardi, P, Saitto, G, D’Annolfo, A, Del Forno, B, Versaci, F, and Chiariello, L
Subjects: Settore MED/23 - Chirurgia Cardiaca
Published: 2012

36. Carotid artery stenting: Findings based on 8 years' experience [Carotid Artery Stenting: risultati dopo otto anni di esperienza]

Author: Simonetti, Gme, Gandini, R, Versaci, F, Pampana, E, Fabiano, S, Stefanini, M, Spinelli, A, Reale, C, Di Primio, M, and Gaspari, E
Subjects: Restenosis, Settore MED/36 - Diagnostica per Immagini e Radioterapia, Follow-up, Angioplasty, Carotid stenosis, Stent
Published: 2009

37. Inflammatory markers predicts future cardiovascular and neurological events in patient undergoing carotid stent implantation

Author: Versaci, F, Del Giudice, C, Gaspardone, A, Condorelli, G, Pellegrino, A, Mauriello, A, Liberatoscioli, L, Proietti, I, Simonetti, Gme, Cortese, C, and Chiariello, L
Subjects: Settore MED/08 - Anatomia Patologica
Published: 2008

38. Sequential hybrid carotid and coronary artery revascularization: SHARP Trial: immediate and midterm results. Proceedings, American Heart Association, scientific sessions 2006

Author: Versaci, F, Del Giudice, C, Nardi, P, Gandini, R, Pampana, E, Fabiano, S, Salvati, A, Scafuri, A, Simonetti, Gme, and Chiariello, L
Subjects: Settore MED/23 - Chirurgia Cardiaca
Published: 2006

39. 33.Free right internal thoracic artery in a 'horseshoe' configuration: a new technical approach for 'in situ' conduit lengthening

Author: Zeitani, J, Penta de Peppo, A, Scafuri, A, Versaci, F, and Chiariello, L
Subjects: Settore MED/23 - Chirurgia Cardiaca
Published: 2005

40. Temporal Sequenze and spatial distribution of ischemic changes during dipyridamole stress test - the key role of microvascular disfunction

Author: Gaspardone, A, Polisca, P, Versaci, F, Tomai, F, Proietti, I, De Matteis GM, Chiariello, L, Gioffrè, P, and Crea, F
Subjects: coronary stenosis, stable angina, dipyridamole, myocardial ischaemia, Settore MED/06
Published: 2005

41. Immunosuppressive oral prednisone after percutaneous interventions in patients with multi-vessel coronary artery disease. The IMPRESS-2/MVD study

Author: Ribichini, F, Tomai, F, Ferrero, V, Versaci, F, Boccuzzi, G, Proietti, I, Prati, F, Crea, F, and Vassanelli, C
Subjects: prednisone, percutaneous interventions, Immunosuppressive oral prednisone, coronary artery disease, Settore MED/06
Abstract: To assess efficacy and safety of oral treatment with prednisone at immunosuppressive dose after percutaneous coronary interventions (PCI) in patients with multi-vessel coronary artery disease (CAD).Eighty-six consecutive patients with multi-vessel CAD were successfully treated with multiple PCI. Forty-three patients (115 coronary stenoses), with C-reactive protein3mg/L 48 hours after PCI and in absence of contra-indications received 45-day high-dose oral prednisone treatment (study-group). Forty-three patients (106 coronary stenoses), did not receive prednisone (control-group). The primary clinical endpoint was 12-month event-free survival rate (defined as freedom from death, myocardial infarction, and the need for target vessel revascularisation). Angiographic restenosis at 8 months was assessed in the study group only. Event-free survival rates were 93 and 69.8% in the study and the control group, respectively (relative risk 0.34, 95%CI: 0.12 to 0.96, p=0.006). Target vessel revascularisation rate in the study group was 7% compared to 27.9% in the control group (p=0.01). Quantitative coronary angiography performed on 104 lesions of 39 prednisone-treated patients (91%) showed 4 restenotic lesions (3.8%). The mean late lumen loss was 0.61+/-0.35mm and loss index 31.3+/-21.6%.Oral immunosuppression with prednisone effectively reduces clinical restenosis in patients undergoing complex, multi-vessel PCI.
Published: 2005

42. Rivascolarizzazione sequenziale ibrida carotidea e coronarica: descrizione del primo caso effettuato

Author: Versaci, F, Ando', Giuseppe, Nardi, P, Proietti, I, Borioni, R, De Fazio, A, Mantione, L, and Chiariello, L.
Published: 2004

43. Esistono alternative agli stent a rilascio di farmaco?

Author: Versaci, F, Ando', Giuseppe, Mezzanotte, R, and DE FAZIO, A.
Published: 2004

44. Relazione tra infiammazione e disfunzione del microcircolo coronarico

Author: Tomai, F, Ribichini, F, Ghini, As, Ferrero, V, Ando', Giuseppe, Versaci, F, Vassanelli, C, Crea, F, Romeo, F, and Chiariello, L.
Published: 2004

45. Effect of sirolimus eluting stents and desametazone covered stents on post-procedural serum levels of C-reactive protein

Author: Gaspardone, A, Citone, C, Versaci, F, Proietti, I, Ando', Giuseppe, Gioffrè, G, Skossyreva, O, Koleva, M, Cogliandro, T, and Tomai, F.
Published: 2004

46. Confronto tra stent ed angioplastica coronarica su stenosi isolata della discendente anteriore prossimale: follow-up a 5 anni

Author: Versaci, F, Proietti, I, Gaspardone, A, Tomai, F, Skossyreva, O, Ando', Giuseppe, De Fazio, A, Iamele, M, Gioffré, Pa, and Chiariello, L.
Published: 2003

47. Computational structural analysis of intravascular stent expansion

Author: Petrini, Lorenza, Migliavacca, Francesco, Colombo, M., Versaci, F., Pietrabissa, Riccardo, and Auricchio, F.
Published: 2002

48. Trombosi acuta dell’arteria del nodo seno atriale: implicazioni aritmologiche

Author: Ando', Giuseppe, Proietti, I, Skossyreva, O, Magliano, G, Gaspardone, A, Lamberti, F, Tomai, F, Versaci, F, Gioffrè, Pa, and Chiariello, L.
Published: 2002

49. Valutazione estemporanea dell’effetto emodinamico della chiusura di pervietà interatriali in pazienti adulti con disfunzione ventricolare sinistra

Author: Ando', Giuseppe, Tomai, F, Papa, M, Gaspardone, A, Versaci, F, Polisca, P, Ghini, As, Proietti, I, Chiariello, L, and Gioffré, Pa
Published: 2002

50. Chiusura percutanea di un difetto interventricolare post-infartuale: variabili predittive del successo procedurale

Author: Proietti, I, Gaspardone, A, Versaci, F, Papa, M, Tomai, F, Turani, F, Polisca, P, Ando', Giuseppe, Gioffré, Pa, and Chiariello, L.
Published: 2002

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Region

Database

Publisher

375 results on '"Versaci, F"'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources