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Education in the XXI century is called to move forward in the right direction and to gain momentum to face diverse challenges and take opportunities offered by the knowledge that is inherent in society. Therefore, it can be postulated that there must be a close relationship between learning, the generation of knowledge, continuous innovation and the use of new technologies. This is a cross-sectional descriptive study conducted among a sample of 242 first year and second year Cadiz University nursing students, using the validated Learning and Study Strategies Inventory questionnaire to assess motivation and the Relationship between Learning Styles and Information and Communication Technologies questionnaire to assess knowledge, use and attitude. The predominant profile type of nursing degree students was women under 21 years old, who were single and exclusively dedicated to their studies. In addition, they showed positive motivation in relation to learning while facing adversity (between 76% and 76.6%). Regarding the level of knowledge, use and attitude towards ICTs, most of the considered items presented high values. For some questions, age was proven to be a sociodemographic variable that influenced both the motivation and attitude of the students. The level of knowledge, use and attitude that students have regarding ICTs are good when we refer to communication technologies, interpersonal relationships or basic programs. However, they are low when considering programs related to education or learning.

La Ectrodactilia Displasia Ectodérmica y Paladar Hendido, es un síndrome que en el caso de nuestro paciente a nivel de la cavidad oral va estar relacionada con alteraciones como agenesias verdaderas, y alteraciones en la estructuras como es la hipoplasia de esmalte que es una alteración donde existe una hipo mineralización que puede variar en la severidad desde manchas, surcos, cavidades en esmalte. En el caso de este paciente de sexo masculino de 12 años de edad. El reto de trabajar con un paciente con este síndrome implica antes de realizar un procedimiento en el paciente aprender sobre este síndrome para poder establecer la empatía desde el momento del interrogatorio y posterior procedimiento poniendo en práctica nuestras destrezas, en el paciente se elige para poder rehabilitar la pieza dentaria con hipoplasia de esmalte las resinas por las propiedades tan nobles como ser la adhesión, estética, fácil manipulación, resistencia a las fuerzas masticatorias. Al momento de la rehabilitación se imposibilita el uso de aislamiento absoluto por que el paciente no accede al uso de este aditamento por temor a atorarse con la saliva, por lo que para controlar la humedad del campo de trabajo se trabaja con aislamiento relativo y sector de saliva por lo que se trabaja a 4 manos, asi también para controlar el factor de contracción del material adhesivo se trabaja capa por capa. Al final del procedimiento el paciente y la madre resultan agradecidos y motivados porque ven que rehabilitar las piezas es posible y manifiestan la intención de continuar con su rehabilitación oral.

La Diabetes Mellitus es una alteración endocrino que se relación con varios factores, puede ser genética o puede desarrollarse por la alimentación rica en hidratos de carbono y puede afectar a diferentes edades de la vida desde niños, adolescentes, jóvenes, adultos, adultos mayores. Cada ves existe más casos de pacientes con esta alteración, relacionado a los hábitos alimenticios y de vida como el sedentarismo. Así también otra patología que va en aumento en estos últimos tiempos es la hipertensión arterial llegando a ser una de las mas frecuentes. En este caso de nuestro paciente adulto presenta la dos patologías por lo que se busca antes de realizar la cirugía que el paciente sea valorado por el médico a través de una interconsulta , donde se solicita controlar la glicemia en sangre y estabilizar la presión arterial. Se explica a la paciente el riesgo de la cirugía en el momento de ser realizada y en el posoperatorio buscando crear sensibilización sobre su estado de salud evitando posibles complicaciones. Se procede a realizar una limpieza como preparación del terreno y al momento de realizar la cirugía se siguen los protocolos establecidos teniendo el cuidado de emplear un anestésico sin vasoconstrictor, tratando de ser lo más conservadores en mantener las tablas Oseas, teniendo el cuidado de realizar sutura para asegurar que el coagulo permanezca dentro del alveolo con la intención de tener éxito en la cicatrización, en el posoperatorio se realiza antisepsia y se educa sobre los cuidados a tener. Al control posoperatorio mediato se logra una cicatrización que conserva espesor y altura de hueso lo que le da oportunidad a la paciente de poder pensar en rehabilitar el espacio edentulo con una protesis o un implante que actualmente se están realizando en pacientes con estas enfermedades de base que estén controlados y estabilizados.

Knee osteoarthritis (OA) is the most common joint disease. The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) by phonophoresis is a therapeutic alternative to relieve pain in inflammatory pathologies. The main aim was to analyze the efficacy of the application of NSAIDs by phonophoresis in knee OA. A systematic review and meta-analysis of controlled clinical trials were performed between January and March 2021 in the following databases: Web of Science, Scopus, PubMed, Cinahl, SciELO, and PEDro. The PEDro scale was used to evaluate the level of evidence of the selected studies. The RevMan 5.4 statistical software was used to obtain the meta-analysis. Eight studies were included, of which five were included in the meta-analysis, involving 195 participants. The NSAIDs used through phonophoresis were ibuprofen, piroxicam, diclofenac sodium, diclofenac diethylammonium, ketoprofen, and methyl salicylate. The overall result for pain showed not-conclusive results, but a trend toward significance was found in favor of the phonophoresis group compared to the control group (standardized mean difference (SMD) = -0.92; 95% confidence interval: -1.87-0.02). Favorable results were obtained for physical function (SMD = -1.34; 95% CI: -2.00-0.68). Based on the selected studies, the application of NSAIDs by phonophoresis is effective in relieving the symptoms of knee OA. Future long-term studies are recommended., Erasmus + Strategic Partnership for Higher Education Program: 2020-1-PL01-KA203-081905.

Carpal tunnel syndrome is a neuropathic disease. It is one of the most frequent musculoskeletal pathologies affecting the upper limbs. One of most frequently used non-surgical treatments is corticosteorids. There are several alternatives for corticosteroids administration. One of them is phonophoresis, this being an effective and painless method of treatment. A systematic review and meta-analysis have been conducted over the use of phonophoresis with corticosteroids for the treatment of carpal tunnel syndrome compared to other non-surgical treatment methods. Keywords from Medical Subjects Headings (MeSH) were used in the following databases: Wos, Scopus, CINHAL, SciELO and PeDro. A total of 222 potentially relevant articles were retrieved. Eleven articles analysing the efficacy of phonophoresis with corticosteroids in reducing pain symptoms in individuals with carpal tunnel syndrome were included, 10 of which were used to conduct the meta-analysis. A conclusion could not be reached as to the application of phonophoresis with corticosteroids being better than other treatment methods, except for the perception of pain and an improved motor and sensory nerve conduction in cases of mild to moderate carpal tunnel syndrome.

Here, we report the draft genome sequence of Paenibacillus odorifer strain V, which was isolated from the fecal material of a rabbit living in the wild. The genome size is 6,863,583 bp, with 44.35 mol% G+C content.

The dinitrophenol herbicide dinoseb is an uncoupler of mitochondrial oxidative phosphorylation (OXPHOS). Studies in fish demonstrate impaired OXPHOS is associated with altered immune system responses and locomotor activity in fish. The objective of this study was to determine the effect of dinoseb on zebrafish (Danio rerio) during early stages of development. We measured oxygen consumption rates of embryos, transcripts related to OXPHOS, growth, and the immune system (cytokines and immune-signaling transcripts), and locomotor activity. We hypothesized that OXPHOS of fish would be impaired in vivo, leading to altered basal immune system expression and locomotor activity. Oxidative respiration assessments in embryos revealed that dinoseb decreased both mean basal respiration and oligomycin-induced ATP-linked respiration. Expression levels of cytochrome c oxidase complex IV, 3-hydroxyacyl-COA dehydrogenase and superoxide dismutase 1 were decreased in larvae following exposure to dinoseb while succinate dehydrogenase complex flavoprotein subunit A, insulin growth factor 1 (igf1) and igf2a mRNA were increased in abundance. Immune-related transcripts chemokine (C-X-C motif) ligand 1 and matrix metallopeptidase 9 (MMP-9) were decreased in expression levels while toll-like receptor 5a and 5b were increased in expression. In addition, a visual motor response test was conducted on both 6 and 7 dpf larvae to determine if dinoseb impaired locomotor activity. Dinoseb decreased locomotor activity in 7 dpf larvae but not 6 dpf. This study improves knowledge of toxicity mechanisms for dinoseb in early stages of fish development and demonstrates that mitochondrial toxicants may disrupt immune signaling in zebrafish.

Breast cancer treatments can trigger respiratory sequelae. Respiratory physiotherapy helps to eliminate or mitigate the sequelae by optimizing respiratory function. This systematic review aims to synthesize the scientific evidence and assess its quality regarding the use of respiratory physiotherapy in the sequelae of breast cancer. The Cochrane Library, Physiotherapy Evidence Database, PubMed, Web of Science, Scientific Electronic Library Online, Cumulative Index of Nursing and Allied Literature Complete, and Scopus were searched. Study quality was determined using the PEDro scale, STROBE Statement, and Single-Case Experimental Design Scale. Ten studies, six clinical trials, one case study, and three observational studies were selected. The mean methodological quality of the clinical trials was 5.6, that of the case study was 7, and that of the observational studies was 56%. Respiratory physiotherapy has been observed to improve respiratory capacity, lung function, respiratory muscle strength, effort tolerance, dyspnea, fatigue, thoracic mobility, upper limb volume, sleep quality and quality of life, as well as sensitivity to adverse physiological reactions, nausea, vomiting, and anxiety. However, it is not effective for vasomotor symptoms. More clinical trials are needed. These studies should homogenize the techniques used, as well as improve their methodological quality This research was funded by the Department of Nursing and Physiotherapy (University of Cadiz). Partial funding for open access charge: Universidad de Málaga

Background: The aim of this systematic review and meta-analysis was to evaluate the global postural re-education (GPR) program's effectiveness compared to other exercise programs in subjects with persistent chronic low back pain. Methods: A systematic review and meta-analysis were carried out using PRISMA2020. An electronic search of scientific databases was performed from their inception to January 2021. Randomized controlled trials that analyzed pain and patient-reported outcomes were included in this review. Four meta-analyses were performed. The outcomes analyzed were disability due to back pain and pain. The risk of bias and quality of evidence were evaluated. The final search was conducted in March. Results: Seven trials were included, totaling 334 patients. The results showed improvement in pain measured by Visual Analogue Scale (VAS) (Standardised Mean Difference (SMD) = -0.69; 95% Confidence Interval (CI), -1.01 to -0.37; p < 0.0001), Numerical Pain Scale (NRS) (SMD = -0.40; 95% CI, -0.87 to 0.06); p = 0.022), VAS + NRS (SMD = -1.32; 95% CI, -1.87 to -0.77; p < 0.0001) and function (Roland Morris Disability Questionnaire (RMDQ)) (SMD = -0.55; 95% CI, -0.83 to -0.27; p < 0.0001) after GPR treatment. Conclusion: This meta-analysis provides reliable evidence that GPR may be an effective method for treating LBP by decreasing pain and improving function, with strong evidence., This research was partially financially supported by the Erasmus+ Strategic Partnership for Higher Education Programme (Key Action 203) [Grant number: 2018-1-PL01-KA203-051055].

The aim of this study was to identify and to assess the best evidence currently available on the effectiveness of oral sensory-motor stimulation in preterm infants in the neonatal intensive care unit. We performed a systematic review following the Preferred Reporting Items for Systematic Reviews (PRISMA) statements. The search was conducted using the Pubmed, Web of Science (WOS), PEDro and Scopus databases. Clinical trials were reviewed and PEDro rating scale was used to assess the methodological quality of these studies. Results: 1267 studies were found and 11 were relevant and included in this review. Improvements were obtained in achieving independent feeding, maturation of the sucking pattern, transition to full feeding, motor function and length of hospital stay in most studies. Conclusions: there is evidence to support the benefits of the use of oral sensorimotor stimulation to achieve independent oral feeding in preterm infants, thereby reducing their stay in the Neonatal Intensive Care Unit.

Background: There are different therapeutic strategies such as physiotherapy and music therapy for the treatment of cerebral palsy. Intervention protocols using both therapies to unify the measurement of motor function have not been investigated. Aims and scope: To summarize the effects of the treatment of cerebral palsy through the use of both for the improvement of motor function, analyse the challenges encountered, and submit proposals for improving them. Methods: The systematic review was conducted following PRISMA guidelines and registered in the PROSPERO database (CRD42020162493). Clinical trials that described the results obtained in terms of motor function through physiotherapy and music therapy were included. Results: Eight clinical trials with 234 participants were considered with a significant improvement in motor function. Results of meta-analysis suggested improvements in gait velocity in favour of the control group for cerebral palsy (mean differences = 0.03; 95% confidence interval = 0.01, 0.04, p = 0.001; I-2 = 97%). However, high heterogeneity was identified in the meta-analysis due to the small number of studies included. Conclusions: The combination can be effective in subjects with cerebral palsy to improve motor function, although due to the diversity of studies analysed, it is complex to extrapolate results., This research was funded by the Department of Nursing and Physiotherapy (University of Cadiz).

BACKGROUND Augmented reality (AR) is a rapidly expanding technology; it comprises the generation of new images from digital information in the real physical environment of a person, which simulates an environment where the artificial and real are mixed. The use of AR in physiotherapy has shown benefits in certain areas of patient health. However, these benefits have not been studied as a whole. OBJECTIVE This study aims to ascertain the current scientific evidence on AR therapy as a complement to physiotherapy and to determine the areas in which it has been used the most and which variables and methods have been most effective. METHODS A systematic review registered in PROSPERO (International Prospective Register of Systematic Reviews) was conducted following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) recommendations. The search was conducted from July to August 2021 in the PubMed, PEDro, Web of Science, Scopus, and Cochrane Library scientific databases using the keywords augmented reality, physiotherapy, physical therapy, exercise therapy, rehabilitation, physical medicine, fitness, and occupational therapy. The methodological quality was evaluated using the PEDro scale and the Scottish Intercollegiate Guidelines Network scale to determine the degree of recommendation. The Cochrane Collaboration tool was used to evaluate the risk of bias. RESULTS In total, 11 articles were included in the systematic review. Of the 11 articles, 4 (36%) contributed information to the meta-analysis. Overall, 64% (7/11) obtained a good level of evidence, and most had a B degree of recommendation of evidence. A total of 308 participants were analyzed. Favorable results were found for the Berg Balance Scale (standardized mean change 0.473, 95% CI −0.0877 to 1.0338; z=1.65; P=.10) and the Timed Up and Go test (standardized mean change −1.211, 95% CI −3.2005 to 0.7768; z=−1.194; P=.23). CONCLUSIONS AR, in combination with conventional therapy, has been used for the treatment of balance and fall prevention in geriatrics, lower and upper limb functionality in stroke, pain in phantom pain syndrome, and turning in place in patients with Parkinson disease with freezing of gait. AR is effective for the improvement of balance; however, given the small size of the samples and the high heterogeneity of the studies, the results were not conclusive. Future studies using larger sample sizes and with greater homogeneity in terms of the devices used and the frequency and intensity of the interventions are needed. CLINICALTRIAL PROSPERO International Prospective Register of Systematic Reviews CRD42020180766; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=180766

Based on stratigraphic excavation data and associated radiocarbon dates we argue that the pre-Hispanic city of Cerro Jazmín, in the Mixteca Alta region of Oaxaca, underwent a period of political change between the Late Formative (300 b.c.–a.d. 50) and the Terminal Formative periods (a.d. 50–300). This shift is reflected in the city's layout and in the timing of construction and use of two different monumental sectors. During the city's Late Formative occupation, we found evidence of more exclusionary feasting activity taking place in a secluded monumental sector called the Sunken Courtyards near the hilltop. In the Terminal Formative, however, monumental construction expanded in the more accessible Tres Cerritos sector where larger and accessible public areas were the focus of activity. We argue that changes in the city's layout, along with the differing patterns of feasting, suggest that the city's leaders went from a more exclusionary form of government to a more collective political strategy during the Terminal Formative period. Despite of these efforts monumental construction largely stopped and the city's population declined by the start of the Classic period (a.d. 300).

Triazole fungicides are increasingly used in North America to combat mold and fungi, in order to protect vegetables, citrus, ornamental plants and field crops. To determine the biological impacts of tebuconazole in non-target aquatic organisms, early life stage zebrafish were exposed to 0.1–100 μM tebuconazole for 120 h (5 dpf). There was a significant increase in mortality over time and at 100 μM, only 50% of the animals survived 96 h compared to >95% for all other experimental groups. There was evidence for increased hatching time with 10 μM tebuconazole compared to the control group (~7 h longer at 50% total hatch) or a lack of hatch observed with 100 μM. Oxidative respiration and behavior were evaluated to assess whether the fungicide impaired energy-associated processes. Oxygen consumption rates in embryos (exposed from ~6 hpf) were determined with exposure to 2.5, 25, 50, 100 μM tebuconazole for 24 h using the XFe24 Extracellular Flux Analyzer. Embryos treated with 100 μM showed a ~60% reduction in basal respiration, indicating impaired oxygen consumption and/or changes in resource allocation (e.g. anti-oxidant production, metabolite synthesis). Environmentally-relevant concentrations of tebuconazole did not affect oxidative phosphorylation. As behavior is a sensitive endpoint for toxicity, we measured the dark photokinesis response and conducted a light-dark preference test in 6 dpf larvae following a sub-chronic exposure to 0.1, 1 and 10 μM tebuconazole beginning with 6 hpf embryos. It was observed in two independent experiments for dark photokinesis that 10 μM tebuconazole reduced total distance moved (i.e. hypoactivity) in the dark period by ~25–35%. In the light-dark preference test, there was an increase for mean time in dark zone (~100% increase in the average time/visits per second) and frequency in dark zone (increase of ~35% in average number of visits) with tebuconazole, suggestive of anxiolytic behavior at environmentally-relevant doses. This study demonstrates that exposure to tebuconazole can affect survival, hatch time, oxidative phosphorylation, and behavioral activity of early-staged zebrafish. While survival, hatch time, and mitochondrial bioenergetics were not different than control fish at environmentally-relevant levels of tebuconazole, behavioral responses were detected at concentrations reported in some aquatic environments.

Objective: To analyze the exercise programs used to prevent of acute hamstring injuries in eleven-a-side football players, and their effectiveness. (2) Methods: A systematic review (PRISMA) was conducted (2008–2020), including RCTs, that exclusively used physical exercises as a prevention method. (3) Results: Ten studies were selected considering 14 interventions, including nine different programs: FIFA11+ (11+), Harmoknee, eccentric Nordic Hamstring Exercise (NHE) exclusively, with eccentric exercises, with stretching or with proprioceptive, New Warm-up Program (NWP), Bounding Exercise Program (BEP), the only one with no positive results, and proprioceptive exercises. Incidence of injuries and strength were the most considered variables, both with favorable evidences. Programs including NHE, which assessed injury incidence, were always effective. The 11+ program was effective in injury incidence and strength; NWP was effective in balance, stability, and strength. (4) Conclusions: The exercise programs discussed were effective to prevent acute hamstring injuries in football players except BEP and partially Harmoknee. Exercises mostly used to reduce the risk of hamstring injuries are those of eccentric force due to its functionality, especially NHE. Only concentric contractions and isometric contractions obtained significant favorable results. The most complete and promising programs were 11+ (in injury incidence and strength) and NWP (strength, balance, and stability). NWP was the best in strength. Erasmus+ Strategic Partnership for Higher Education Program (Key Action 203), 2018-1-PL01-KA203-051055