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351 results on '"Verma, Shyam B."'

2. Trichophyton mentagrophytes ITS Genotype VIII/ Trichophyton indotineae Infection and Antifungal Resistance in Bangladesh.

Author

Bhuiyan, Mohammed Saiful Islam, Verma, Shyam B., Illigner, Gina-Marie, Uhrlaß, Silke, Klonowski, Esther, Burmester, Anke, Noor, Towhida, and Nenoff, Pietro

Subjects
*TERBINAFINE, *RINGWORM, *PUBLIC health, *FUNGAL colonies, *POLYMERASE chain reaction
Abstract

Trichophyton (T.) mentagrophytes ITS genotype VIII, also known as Trichophyton indotineae, is a new species of the T. mentagrophytes/T. interdigitale complex and its first records, albeit under a different species name, are from the Indian subcontinent, Middle Eastern Asia, and West Asia. T. mentagrophytes genotype VIII (T. indotineae) has spread globally and has now been documented in over 30 countries. The aim of this study was to investigate the occurrence and proportion of terbinafine- and itraconazole-resistant isolates of T. mentagrophytes ITS genotype VIII (T. indotineae) in Bangladesh. This was part of an official collaborative project between IADVL (Indian Association of Dermatologists, Venereologists, and Leprologists) and Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh. Over a period of 6 months, ninety-nine patients of chronic recalcitrant tinea corporis were recruited from BSMMU hospital. Species identification was performed by fungal culture and morphological observation of the upper and lower surfaces of fungal colonies, as well as by using fluorescent microscopy. In addition, a PCR (polymerase chain reaction)-ELISA was performed to group the patients into those with the T. mentagrophytes/T. interdigitale complex. The internal transcribed spacer (ITS) gene was sequenced. Samples were tested for resistance to terbinafine and itraconazole by mutational analyses of the squalene epoxidase (SQLE) and the ergosterol 11B (ERG11B) genes. A total of 79/99 samples showed a positive culture. In 76 of these isolates, T. mentagrophytes ITS genotype VIII (T. indotineae) could be reliably identified both by culture and molecular testing. Resistance testing revealed terbinafine resistance in 49 and itraconazole resistance in 21 patients. Among these, 11 patients were resistant to both the antifungal agents. Mutations L393S, L393F, F397L, and F397I of the SQLE gene were associated with terbinafine resistance. Resistance to itraconazole could not be explained by mutations in the ERG11B gene. Infections with T. mentagrophytes ITS genotype VIII (T. indotineae) have become a public health issue with potentially global ramifications. About 62% of samples from Bangladesh showed resistance to terbinafine, making oral itraconazole the most effective drug currently available, although resistance to itraconazole and both terbinafine and itraconazole also exists. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Rosacea in Dark Skin

Author

Wollina, Uwe, Ogunbiyi, Adebola, Verma, Shyam B., Ashique, Karalikkattil T., Orfanos, Constantin E., editor, Zouboulis, Christos C., editor, and Assaf, Chalid, editor

Published
2018
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15. Treatment of Rhinophyma

Author

Wollina, Uwe, Verma, Shyam B., Zouboulis, Christos C., editor, Katsambas, Andreas D., editor, and Kligman, Albert M., editor

Published
2014
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21. Authors’ reply

Author

Verma, Shyam B., primary, Panda, Saumya, additional, Nenoff, Pietro, additional, Singal, Archana, additional, Rudramurthy, Shivaprakash M., additional, Uhrlass, Silke, additional, Das, Anupam, additional, Bisherwal, Kavita, additional, Shaw, Dipika, additional, and Vasani, Resham, additional

Published
2021
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24. Secondary dermatoses over scars and striae—A phenomenon replete with miscellaneous terms indicating dysregulated immunity.

Author

Verma, Shyam B., Moudgil, Shivani, Mahajan, Rahul, and Ramamoorthy, Ramkumar

Subjects
*SCARS, *SKIN diseases, *VITILIGO, *HYPERTROPHIC scars, *REGULATORY T cells, *TOTAL knee replacement
Abstract

The present study is a retrospective chart review of 10 consecutive patients presenting to us with scars or striae as the primary skin condition with an overlying unrelated secondary dermatosis. Secondary dermatoses over scars and striae - A phenomenon replete with miscellaneous terms indicating dysregulated immunity A scar is a confined area of fibrous tissue resulting from the process of wound repair which replaces normal skin after an injury. [Extracted from the article]

Published
2023
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25. Topical corticosteroid induced ulcerated striae

Author

Verma, Shyam B. and Madke, Bhushan

Subjects
Striae distensae, Adverse effects, Ulceration, Topical steroid, eye diseases
Abstract

We report four cases of ulcerated striae following misuse of fixed dose combinations creams containing clobetasol propionate with antifungal and antibacterial agents.

Published
2021

39. Spread of Terbinafine-Resistant Trichophyton mentagrophytes Type VIII (India) in Germany–“The Tip of the Iceberg?”

Author

Nenoff, Pietro, primary, Verma, Shyam B., additional, Ebert, Andreas, additional, Süß, Anke, additional, Fischer, Eleni, additional, Auerswald, Elke, additional, Dessoi, Stephanie, additional, Hofmann, Wencke, additional, Schmidt, Simone, additional, Neubert, Kathrin, additional, Renner, Regina, additional, Sohl, Sirius, additional, Hradetzky, Uta, additional, Krusche, Ursula, additional, Wenzel, Hans-Christian, additional, Staginnus, Annegret, additional, Schaller, Jörg, additional, Müller, Valentina, additional, Tauer, Christiane, additional, Gebhardt, Matthias, additional, Schubert, Katja, additional, Almustafa, Zaid, additional, Stadler, Rudolf, additional, Fuchs, Andrea, additional, Sitaru, Cassian, additional, Retzlaff, Carsten, additional, Overbeck, Cora, additional, Neumann, Thomas, additional, Kerschnitzki, Anette, additional, Krause, Stephan, additional, Schaller, Martin, additional, Walker, Birgit, additional, Walther, Thomas, additional, Köhler, Lars, additional, Albrecht, Manuela, additional, Willing, Ursula, additional, Monod, Michel, additional, Salamin, Karine, additional, Burmester, Anke, additional, Koch, Daniela, additional, Krüger, Constanze, additional, and Uhrlaß, Silke, additional

Published
2020
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43. Alarming India‐wide phenomenon of antifungal resistance in dermatophytes: A multicentre study

Author

Ebert, Andreas, primary, Monod, Michel, additional, Salamin, Karine, additional, Burmester, Anke, additional, Uhrlaß, Silke, additional, Wiegand, Cornelia, additional, Hipler, Uta‐Christina, additional, Krüger, Constanze, additional, Koch, Daniela, additional, Wittig, Franziska, additional, Verma, Shyam B., additional, Singal, Archana, additional, Gupta, Sanjeev, additional, Vasani, Resham, additional, Saraswat, Abir, additional, Madhu, Rengarajan, additional, Panda, Saumya, additional, Das, Anupam, additional, Kura, Mahendra M., additional, Kumar, Akshy, additional, Poojary, Shital, additional, Schirm, Sibylle, additional, Gräser, Yvonne, additional, Paasch, Uwe, additional, and Nenoff, Pietro, additional

Published
2020
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45. A Puzzling Hyperpigmented and Hyperkeratotic Nodule on the Leg of a Young Indian Woman.

Author

Verma, Shyam B. and Ghosh, Kisalay A.

Subjects
*KERATOSIS, *HYPERPIGMENTATION, *SKIN tumors, *LEG, *CYTOCHEMISTRY, *DERMOSCOPY, *EPIDERMIS, CONNECTIVE tissue tumors
Abstract

The article focuses on a case study of a rare lipidized fibrous histiocytoma (LFH) in a young Indian woman, detailing its clinical presentation as a hyperpigmented and hyperkeratotic nodule on the leg. It covers the diagnostic challenges, histopathological features, and a comparative analysis of LFH with other dermatofibromas, emphasizing the rarity of this variant and its distinct presentation in Fitzpatrick type IV skin.

Published
2023
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