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14. Viral and Cellular Fos Gene

Author

Verma, I. M., Curran, T., Miller, A. D., Van Beveren, C., Furmanski, Philip, editor, Hager, Jean Carol, editor, and Rich, Marvin A., editor

Published
1985
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15. Towards Gene Therapy for Adenosine Deaminase Deficiency

Author

Valerio, D., van Beusechem, V. W., Einerhand, M. P. W., Hoogerbrugge, P. M., van der Putten, H., Wamsley, P. M., Berkvens, Th. M., Verma, I. M., Kellems, R. E., van Bekkum, D. W., Baum, S. J., editor, Dicke, K. A., editor, Lotzová, E., editor, and Pluznik, D. H., editor

Published
1989
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16. Homology Among Oncogenes

Author

Van Beveren, C., Verma, I. M., Clarke, A., editor, Compans, R. W., editor, Cooper, M., editor, Eisen, H., editor, Goebel, W., editor, Koprowski, H., editor, Melchers, F., editor, Oldstone, M., editor, Rott, R., editor, Vogt, P. K., editor, Wagner, H., editor, Wilson, I., editor, Vogt, Peter K., editor, and Koprowski, Hilary, editor

Published
1986
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17. Expression of Cellular Oncogenes

Author

Müller, R., Verma, I. M., Cooper, M., editor, Goebel, W., editor, Hofschneider, P. H., editor, Koprowski, H., editor, Melchers, F., editor, Oldstone, M., editor, Rott, R., editor, Schweiger, H. G., editor, Vogt, P. K., editor, Zinkernagel, R., editor, Vogt, Peter K., editor, and Koprowski, Hilary, editor

Published
1984
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20. Response of fenugreek (Trigonella foenum-graecum) to bio-regulators TGA and N-acetyl cystein under drip irrigation levels.

Author

Bhunia, S. R., Verma, I. M., and Arif, M.

Subjects
*FENUGREEK, *MICROIRRIGATION, *CYSTEINE
Abstract

Field experiments were conducted during winter seasons of 2010-11 and 2011-12 at Bikaner (Rajasthan) to study the effect of bioregulators viz., TGA and N-acetyl cystein under different drip irrigation levels on yield, yield attributes, water use and water use efficiency of fenugreek. The highest plant height (69 cm) and yield attributes viz., branches plant-1 (7.6), pods plant-1 (46.3), pod length (13.5 cm), seed pod-1 (16) and test weight (12.7 g) were recorded with 100% ETc + TGA (200 ppm). Further, 80% ETc + TGA (200 ppm), and 100% ETc + N-acetyl cystein (both 10 and 20 ppm) and 100% ETc + TGA (both 100 and 200 ppm) produced comparable plant height. However, 80% ETc + N-acetyl cystein (both 10 and 20 ppm), 80% ETc + TGA (both 100 and 200 ppm), 100% ETc + N-acetyl cystein (both 10 and 20 ppm), 100% ETc + TGA (100 ppm) and 100% ETc + TGA (200 ppm) recorded at par branches plant-1, pods plant-1, pod length and test weight of fenugreek. Highest seed and biological yield of fenugreek were recorded with 100% ETc + Nacetyl cystein (20 ppm), which was at par with 100% ETc + N-acetyl cystein (10 ppm) and 100% ETc + TGA (both 100 and 200 ppm). Maximum water use recorded at 100% ETc with or without bioregulators, whereas maximum water use efficiency was recorded with 60% ETc + N-acetyl cystein (20 ppm) followed by 60% ETc + N-acetyl cystein (10 ppm). [ABSTRACT FROM AUTHOR]

Published
2017
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28. Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines

Author

Miyamoto, S, Chiao, P J, and Verma, I M

Subjects
B-Lymphocytes, Base Sequence, Genes, Immunoglobulin, Immune Sera, Tosylphenylalanyl Chloromethyl Ketone, Molecular Sequence Data, Restriction Mapping, NF-kappa B, Blotting, Northern, Cell Line, DNA-Binding Proteins, Immunoglobulin kappa-Chains, Kinetics, Mice, NF-KappaB Inhibitor alpha, Oligodeoxyribonucleotides, Animals, I-kappa B Proteins, Amino Acid Sequence, Peptides, Research Article
Abstract

Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor which binds to decameric DNA sequences (kappa B sites) and regulates transcription of multiple genes. The activity of NF-kappa B is regulated by an inhibitor protein, I kappa B, which sequesters NF-kappa B in the cytoplasm. Release of I kappa B and subsequent nuclear translocation of NF-kappa B generally require activating signals. However, in mature murine B cells, the DNA-binding activity of NF-kappa B is constitutively nuclear and activates the Ig kappa gene, a marker for mature B cells. To understand the basis for the constitutive NF-kappa B activation, we examined the properties of NF-kappa B and I kappa B in both pre-B and mature B cells, the regulated and constitutive states, respectively. We found that expression of I kappa B alpha and p105, members of the I kappa B family, and Rel, a member of the NF-kappa B family, is augmented in mature B cells. Both I kappa B alpha and p 105 are associated with NF-kappa B proteins and sequester most of these proteins in the cytoplasm of mature B cells. However, rapid I kappa B alpha dissociation and degradation lead to continuous nuclear translocation of a small fraction of NF-kappa B proteins, which represent the constitutively active NF-kappa B in mature B cells. We estimate that the protease activity is at least 35-fold greater in mature B cells than in pre-B cells. Rapid degradation of I kappa B alpha is directly involved in constitutive NF-kappa B activation, because stabilization of I kappa B alpha by a protease inhibitor causes loss of NF-kappa B activity in mature B cells. These results provide evidence that continuous and rapid degradation of I kappa B alpha in the absence pf external stimuli is causally involved in the constitutive activation of NF-kappa B in mature murine B cells.

Published
1994

31. Effect of drip irrigation and bioregulators on yield, economics and water use of fenugreek (Trigonella foenum-graecum).

Author

Bhunia, S. R., Verma, I. M., Sahu, M. P., Sharma, N. C., and Balai, K.

Subjects
*MICROIRRIGATION, *THIOUREA, *WATER in agriculture, *AGRICULTURAL water supply, *FENUGREEK, *TRIGONELLA
Abstract

The field experiment was conducted during winter seasons of 2009-10 and 2010-11 to assess the effect of drip irrigation levels and bioregulators (thiourea and Thioglycollic acid) on fenugreek. Increasing levels of drip irrigation from 0.6 to 1.0 ETc enhanced yield attributes viz., branches plant-1, pods plant-1, pod length, seeds pod-1 and test weight. Increased yield attributes with 1.0 ETc thus, enhanced seed yield (15.53 q ha-1) and stover yield (31.54 q ha-1). However highest B:C ratio (2.11) was recorded with 0.8 ETc irrigation level and highest water use efficiency of 4.83 kg ha-1 mm with 0.6 ETc. Recommended surface irrigation treatment recorded 13.02 q ha-1 seed yield with using 540 mm of water. Whereas, fenugreek under drip irrigation at 0.6, 0.8 and 1.0 ETc used 278.16, 370.88 and 463.60 mm of water, respectively. Seed treatment of fenugreek before sowing with bio-regulator thiourea (500 ppm) for 4 h recorded higher yield attributes viz., pods plant-1, pod length and test weight, as well as, seed yield of 14.85 q ha-1 against 14.36 q ha-1 where no seed treatment was done. Thus, in turn fetched higher water use efficiency (4.00 kg ha-1 mm) and B:C ratio (2.08). Further, foliar spray with 200 ppm thioglycollic acid at vegetative and seed formation stages recorded highest seed yield of 15.01 q ha-1 over 100 ppm thioglycollic acid spray (14.59 q ha-1) or no spray treatment (14.21 q ha-1). Increased yield thus enhanced water use efficiency (3.93-4.05 kg ha-1 mm) and B:C ratio (2.06-2.11) in thioglycollic acid treated crop. [ABSTRACT FROM AUTHOR]

Published
2015

32. Effect of FYM, foliar feeding of nitrogen and deficit irrigation on drip irrigated coriander (Coriandrum sativum L.).

Author

Verma, I. M., Bhunia, S. R., Sharma, N. C., Balai, K., and Sahu, M. P.

Subjects
*FOLIAR feeding, *APPLICATION of liquid fertilizers, *DEFICIT irrigation, *IRRIGATION scheduling, *AGRICULTURAL water supply
Abstract

A field experiment was conducted to study the water use, nitrogen (N) uptake and economics of coriander (Coriandrum sativum L.) under organic enrichment, foliar feeding of N and fertigation. Drip irrigation at 80% ETc + foliar spray of 25% N (15 kg ha-1) + fertigation (45 kg ha-1) gave the highest plant height, branch plant-1, umbel plant-1, umbelets umbel-1, seed umbel-1, and test weight compared to irrigation at 80% ETc and at 60% ETc (upto flowering stage) + 80% ETc (reproductive stage) with or without foliar spray. Increased yield parameters were attributed to the highest seed yield and B:C ratio of 1.90 using 265.74 mm water. Water use efficiency (WUE) was also the highest. This treatment also recorded the highest N uptake of 52.6 kg ha-1. Further, addition of 10 t ha-1 FYM in addition to recommended nitrogen dose (60 kg ha-1) gave higher yield attributes viz., branch plant-1, umbel plant-1, seed umbel-1 and test weight as compared to recommended level of fertilizers. Enhanced yield attributes thus increased seed yield, N removal, WUE and B:C ratio. [ABSTRACT FROM AUTHOR]

Published
2015

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