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3. Electrically Induced Blink for the Prevention of Ocular Symptoms and Blurred Vision in Patients With Acute Facial Nerve Palsy.

Author

Mäkelä, Eeva, Venesvirta, Hanna, Ilves, Mirja, Lylykangas, Jani, Rantanen, Ville, Uusitalo, Hannu, Verho, Jarmo, Vehkaoja, Antti, Lekkala, Jukka, Surakka, Veikko, and Rautiainen, Markus

Subjects
BELL'S palsy, VISION disorders, DATA analysis, T-test (Statistics), RESEARCH funding, QUESTIONNAIRES, DESCRIPTIVE statistics, TELEVISION, FACIAL nerve diseases, ELECTRIC stimulation, STATISTICS, ONE-way analysis of variance, DRY eye syndromes, VISUAL acuity, DATA analysis software, BLINKING (Physiology)
Abstract

Objectives : Facial nerve palsy causes blurred vision and ocular discomfort due to deficits in blinking and eye closure. The objective of this study was to determine whether eye-blinks could be elicited by electrical stimulation and whether electrically induced blink would have an effect on the visual acuity and ocular symptoms in patients with acute facial nerve palsy. Methods : The zygomatic branch of the facial nerve of fifteen participants with acute facial nerve palsy was electrically stimulated in order to elicit a blink. In successful cases, the participant proceeded with a two-hour TV watching session in which an electrically induced blink was delivered every 5 seconds. The control condition consisted of an otherwise similar TV watching session without electrically induced blinking. Subjective ocular symptoms were evaluated with a Dry Eye Questionnaire and visual acuity was assessed with a Logarithm of the Minimum Angle of Resolution (LogMAR) chart before and after both sessions. Results : The stimulation produced a blink in 8 participants (53%). The visual acuity in the affected eye decreased during the control session, whereas no significant change occurred during the stimulation session. The ocular symptoms were significantly reduced during the stimulation session. Conclusions : Electrically elicited blink is a promising method for reducing the eye symptoms in individuals with acute facial nerve palsy. [ABSTRACT FROM AUTHOR]

Published
2024
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4. TangoTM Wellness Motivator for Supporting Permanent Lifestyle Change

Author

Vehkaoja, Antti, Verho, Jarmo, Peltokangas, Mikko, Rantaniva, Teppo, Jeyhani, Vala, Råglund, Jari, Magjarevic, Ratko, Editor-in-Chief, Ładyżyński, Piotr, Series Editor, Ibrahim, Fatimah, Series Editor, Lacković, Igor, Series Editor, Rock, Emilio Sacristan, Series Editor, Lhotska, Lenka, editor, Sukupova, Lucie, editor, and Ibbott, Geoffrey S., editor

Published
2019
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6. Short-term stability of combined finger and toe photoplethysmogram analysis

Author

Peltokangas, Mikko, Huotari, Matti, Verho, Jarmo, Mattila, Ville M., Röning, Juha, Romsi, Pekka, Lekkala, Jukka, Vehkaoja, Antti, Oksala, Niku, Magjarevic, Ratko, Editor-in-chief, Ładyżyński, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, Eskola, Hannu, editor, Väisänen, Outi, editor, Viik, Jari, editor, and Hyttinen, Jari, editor

Published
2018
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7. Artificial Eye Blink Pacemaker - A First Investigation into the Blink Production Using Constant-Interval Electrical Stimulation

Author

Lylykangas, Jani, Ilves, Mirja, Venesvirta, Hanna, Rantanen, Ville, Mäkelä, Eeva, Vehkaoja, Antti, Verho, Jarmo, Lekkala, Jukka, Rautiainen, Markus, Surakka, Veikko, Magjarevic, Ratko, Editor-in-chief, Ładyżyński, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, Eskola, Hannu, editor, Väisänen, Outi, editor, Viik, Jari, editor, and Hyttinen, Jari, editor

Published
2018
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8. Day-to-day repeatability of the results of the finger-toe-plot analysis

Author

Peltokangas, Mikko, Telembeci, Anca A., Verho, Jarmo, Lekkala, Jukka, Vehkaoja, Antti, Oksala, Niku, Magjarevic, Ratko, Editor-in-chief, Ładyżyński, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, Eskola, Hannu, editor, Väisänen, Outi, editor, Viik, Jari, editor, and Hyttinen, Jari, editor

Published
2018
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14. Prosthetic Pacing Device for Unilateral Facial Paralysis

Author

Rantanen, Ville, Vehkaoja, Antti, Verho, Jarmo, Veselý, Petr, Lylykangas, Jani, Ilves, Mirja, Mäkelä, Eeva, Rautiainen, Markus, Surakka, Veikko, Lekkala, Jukka, Magjarevic, Ratko, Editor-in-chief, Ładyżyński, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, Kyriacou, Efthyvoulos, editor, Christofides, Stelios, editor, and Pattichis, Constantinos S., editor

Published
2016
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19. Performance of a Near-Field Radio-Frequency Pressure Sensing Method in Compression Garment Application

Author

Salpavaara, Timo Juhani, Verho, Jarmo, Kumpulainen, Pekka, Akan, Ozgur, Series editor, Bellavista, Paolo, Series editor, Cao, Jiannong, Series editor, Dressler, Falko, Series editor, Ferrari, Domenico, Series editor, Gerla, Mario, Series editor, Kobayashi, Hisashi, Series editor, Palazzo, Sergio, Series editor, Sahni, Sartaj, Series editor, Shen, Xuemin (Sherman), Series editor, Stan, Mircea, Series editor, Xiaohua, Jia, Series editor, Zomaya, Albert, Series editor, Coulson, Geoffrey, Series editor, Nikita, Konstantina S., editor, Lin, James C., editor, Fotiadis, Dimitrios I., editor, and Arredondo Waldmeyer, Maria-Teresa, editor

Published
2012
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20. Wearable System for EKG Monitoring - Evaluation of Night-Time Performance

Author

Vehkaoja, Antti, Verho, Jarmo, Cömert, Alper, Honkala, Markku, Lekkala, Jukka, Akan, Ozgur, Series editor, Bellavista, Paolo, Series editor, Cao, Jiannong, Series editor, Dressler, Falko, Series editor, Ferrari, Domenico, Series editor, Gerla, Mario, Series editor, Kobayashi, Hisashi, Series editor, Palazzo, Sergio, Series editor, Sahni, Sartaj, Series editor, Shen, Xuemin (Sherman), Series editor, Stan, Mircea, Series editor, Xiaohua, Jia, Series editor, Zomaya, Albert, Series editor, Coulson, Geoffrey, Series editor, Nikita, Konstantina S., editor, Lin, James C., editor, Fotiadis, Dimitrios I., editor, and Arredondo Waldmeyer, Maria-Teresa, editor

Published
2012
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27. Prosthetic Pacing Device for Unilateral Facial Paralysis

Author

Rantanen, Ville, primary, Vehkaoja, Antti, additional, Verho, Jarmo, additional, Veselý, Petr, additional, Lylykangas, Jani, additional, Ilves, Mirja, additional, Mäkelä, Eeva, additional, Rautiainen, Markus, additional, Surakka, Veikko, additional, and Lekkala, Jukka, additional

Published
2016
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33. Effect of pulse waveforms on movement amplitudes and perceived discomfort in electric muscle stimulation in unresolved facial nerve palsy

Author

Mäkelä, Eeva A, primary, Ilves, Mirja K, additional, Venesvirta, Hanna M, additional, Lylykangas, Jani K, additional, Rantanen, Ville T, additional, Vehkaoja, Antti T, additional, Verho, Jarmo A, additional, Lekkala, Jukka, additional, Surakka, Veikko V, additional, and Rautiainen, Markus E P, additional

Published
2020
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34. Cardiomyocytes: Analysis of Temperature Response and Signal Propagation Between Dissociated Clusters Using Novel Video-Based Movement Analysis Software

Author

Rajan, Dhanesh Kattipparambil, primary, Maki, Antti-Juhana, additional, Pekkanen-Mattila, Mari, additional, Kreutzer, Joose, additional, Ryynanen, Tomi, additional, Valimaki, Hannu, additional, Verho, Jarmo, additional, Koivumaki, Jussi T., additional, Ihalainen, Heimo, additional, Aalto-Setala, Katriina, additional, Kallio, Pasi, additional, and Lekkala, Jukka, additional

Published
2020
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35. Lower limb pulse rise time as a marker of peripheral arterial disease

Author

Peltokangas, Mikko, Vakhitov, Damir, Suominen, Velipekka, Korhonen, Janne, Huotari, Matti, Verho, Jarmo, Röning, Juha, Mattila, Ville M., Romsi, Pekka, Oksala, Niku, Vehkaoja, Antti, Tampere University, BioMediTech, Department of Musculoskeletal Diseases, Clinical Medicine, Verisuoni- ja toimenpideradiologinen keskus, Research group: Sensor Technology and Biomeasurements (STB), and Lääketieteen ja terveysteknologian tiedekunta - Faculty of Medicine and Health Technology

Subjects
Adult, pulse wave measurements, medicine.medical_specialty, Biolääketieteet - Biomedicine, Arterial disease, 0206 medical engineering, Kirurgia, anestesiologia, tehohoito, radiologia - Surgery, anesthesiology, intensive care, radiology, Biomedical Engineering, pulse rise time, 02 engineering and technology, Lower limb, Peripheral Arterial Disease, Young Adult, Heart Rate, peripheral arterial disease, Internal medicine, Photoplethysmogram, medicine, Humans, Photoplethysmography, Aged, Pulse (signal processing), business.industry, Signal Processing, Computer-Assisted, 217 Medical engineering, Index finger, Middle Aged, 020601 biomedical engineering, Peripheral, body regions, medicine.anatomical_structure, Lower Extremity, Cardiology, Upper limb, photoplethysmography, atherosclerosis, Pulse rise time, business
Abstract

Objective: The aim of the study was to show if pulse rise times (PRTs) extracted from photoplethysmographic (PPG) pulse waves (PWs) have an association with peripheral arterial disease (PAD) or its endovascular treatment, percutanoeus transluminal angioplasty (PTA) of the superficial femoral artery. Methods: Lower and upper limb PPG PWs were recorded and analyzed from 24 patients who suffered from PAD. The measurements were conducted before and after the treatment, and one month later by using transmission-mode PPG-probes placed in the index finger and second toe. Ankle-to-brachial pressure index and toe pressures were used as references in clinical patient measurements. PRTs, i.e., the time from the foot point to the peak point of the PW, were extracted from the PWs and compared bilaterally. The results from the PAD patients were also compared with 31 same-aged and 34 younger control subjects. Results: Statistically significant differences were found between the pretreatment PRTs of the treated limb of the PAD patients and the same-aged control subjects ( $p< 10^{-9}$ , Mann–Whitney U-test). The changes in the PRT of the treated lower limb were observed immediately after the PTA ( $p< 0.001$ , Student's t -test), and after one month ( $p< 0.0005$ ), whereas the PRTs of the non-treated lower limb and upper limb did not indicate changes between different examinations. Conclusion: Results show that a PRT greater than 240 ms indicates PAD-lesions in the lower limb. Significance: This proof-of-concept study suggests that the PRT could be an effective and easy-to-use indicator for PAD and monitoring the effectiveness of its treatment. acceptedVersion

Published
2019

36. DS_TECH768710 – Supplemental material for A Portable Microscale Cell Culture System with Indirect Temperature Control

Author

Antti-Juhana Mäki, Verho, Jarmo, Joose Kreutzer, Ryynänen, Tomi, Dhanesh Rajan, Pekkanen-Mattila, Mari, Ahola, Antti, Hyttinen, Jari, Aalto-Setälä, Katriina, Lekkala, Jukka, and Kallio, Pasi

Subjects
FOS: Clinical medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplemental material, DS_TECH768710 for A Portable Microscale Cell Culture System with Indirect Temperature Control by Antti-Juhana Mäki, Jarmo Verho, Joose Kreutzer, Tomi Ryynänen, Dhanesh Rajan, Mari Pekkanen-Mattila, Antti Ahola, Jari Hyttinen, Katriina Aalto-Setälä, Jukka Lekkala and Pasi Kallio in SLAS Technology

Published
2018
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37. Lower Limb Pulse Rise Time as a Marker of Peripheral Arterial Disease

Author

Peltokangas, Mikko, primary, Vakhitov, Damir, additional, Suominen, Velipekka, additional, Korhonen, Janne, additional, Huotari, Matti, additional, Verho, Jarmo, additional, Roning, Juha, additional, Mattila, Ville M., additional, Romsi, Pekka, additional, Oksala, Niku, additional, and Vehkaoja, Antti, additional

Published
2019
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39. Facial muscle reanimation by transcutaneous electrical stimulation for peripheral facial nerve palsy

Author

Mäkelä, Eeva, primary, Venesvirta, Hanna, additional, Ilves, Mirja, additional, Lylykangas, Jani, additional, Rantanen, Ville, additional, Ylä-Kotola, Tuija, additional, Suominen, Sinikka, additional, Vehkaoja, Antti, additional, Verho, Jarmo, additional, Lekkala, Jukka, additional, Surakka, Veikko, additional, and Rautiainen, Markus, additional

Published
2019
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44. Smile to save it

Author

Venesvirta, Hanna, primary, Špakov, Oleg, additional, Gizatdinova, Yulia, additional, Tuisku, Outi, additional, Rantanen, Ville, additional, Verho, Jarmo, additional, Vetek, Akos, additional, Lekkala, Jukka, additional, and Surakka, Veikko, additional

Published
2017
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45. Indirect Temperature Measurement in a Cell Culture Device

Author

Mki Antti-Juhana, Ryynnen Tomi, Yue Yong, Zhu Xiaohui, Kreutzer Joose, Kallio Pasi, Verho Jarmo, and Lekkala Jukka

Subjects
Materials science, Cell culture, General Neuroscience, Biophysics, Temperature measurement
Published
2016

46. Device for Studying Reanimation of Unilateral Facial Paralysis

Author

Rantanen, Ville, Vehkaoja, Antti Tapio, Verho, Jarmo Antero, Veselý, Petr, Kontunen, Anton, Mattila, Raisa, Lylykangas, Jani, Ilves, Mirja, Mäkelä, Eeva, Rautiainen, Markus, Surakka, Veikko, Lekkala, Jukka Olavi, Tampere University, Department of Automation Science and Engineering, Research area: Microsystems, and Research area: Measurement Technology and Process Control

Subjects
217 Medical engineering
Abstract

A device for studying facial pacing for people who suffer from unilateral facial paralysis is presented. The device is able to measure electromyographic (EMG) signals from the healthy side of the face and simultaneously activate the paralysed side with electrical stimulation. Electronics designed for the device are integrated to a single tabletop unit together with a myRIO embedded hardware device by National Instruments (NI). The presented device is designed to fulfil the safety requirements of the Council Directive 93/42/EEC of the European Union concerning medical devices and IEC 60601 standards. The device is powered by a commercial medical grade power source. The custom electronics include isolated measurement and stimulation amplifiers that feed the signals to and from the myRIO. Complex real-time processing can be carried out in the myRIO's FPGA circuit for detecting muscle activations and producing appropriate stimulation signals. The functionality is programmed with NI LabVIEW. The device is controlled wirelessly via a computer interface, and the measured data is logged to the computer. Clinical study with the device is about to be started at the Tampere University Hospital. First trials will determine and compare the required stimulation signal waveform parameters for transcutaneous activation of facial muscles of healthy participants and patients suffering from unilateral facial paralysis. Four measurement and four stimulation channels of the device enable studying different electrode configurations and stimulation patterns for recognizing and reanimating symmetrical facial expressions in the future.

Published
2015

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