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Six cases of intestinal anisakiasis, or herring worm disease, diagnosed over a two year period in a Belgian gastroenterology unit are described. They presented mainly as intestinal obstructions and larvae of this marine nematode were found in the intestinal wall of two of the four patients who were operated on. In two other patients awareness of the diagnosis permitted conservative treatment and spontaneous healing. In five patients symptoms developed after they had eaten herring marinated in vinegar, a hitherto little known source of the herring worm disease. [ABSTRACT FROM PUBLISHER]

Background: Hairdressers are exposed to various work-related biomechanical and organizational risk factors. To date, there has been no overview of the evidence for this occupational group. The purpose of this scoping review is to gain insight into the current state of research on work-related musculoskeletal disorders (MSD) in hairdressing., Methods: Studies published up to November 2018 were identified by a systematic search using electronic databases (MEDLINE, PUBMED, CINAHL, Web of Science, LIVIVO), Google Scholar and reference lists of articles. Studies were screened by two researchers and synthesized in a descriptive manner., Results: Overall 44 studies with different study designs, scopes and approaches were included. Nineteen studies provided data on MSD prevalence in at least one body site. The prevalence values between the studies varied considerably. On average, the highest 12-month prevalence was reported for the lower back (range 13-76%), neck (range 9-58%), shoulder (range 28-60%) and hand/wrist (range 11-53%). In comparison to other occupational groups, hairdressers reported more frequent MSD in all body regions or exhibited a greater risk of leaving the profession for health reasons. Common risk factors include working with arms above shoulder level, repetitive movements, forceful exertion of upper extremities, awkward back postures and movements, high mechanical workload and standing. In addition to physical stress, lack of adequate breaks, overtime, and general distress may deteriorate health and performance of hairdressers. Three rehabilitative and three preventive interventional studies were found. Only the rehabilitative studies showed positive effects on the management of physical and mental strain and resulted in significant pain reduction, increased physical capacity and knowledge of potential risk factors for MSD., Conclusion: This data provides some evidence for work-related risk factors for MSD in hairdressers and indicate that there should be an intense focus on preventive measures. High quality and long-term interventional studies are needed to clarify the effectiveness of complex preventive concepts in hairdressing., Competing Interests: Competing interestsThe authors declare that they have no competing interests.

In a review of the literature concerning autoimmune pancreatitis we had special interest for the concept of IgG4-related pathology as a systemic disease with several clinical manifestations. In general, IgG4-positivity can not only be found in the pancreas, but also at the level of the kidneys, extrahepatic biliary ducts, gallbladder, lungs, salivary glands, lacrimal glands, retroperitoneal tissue, ureters, prostate, meninges and lymph nodes. IgG4 seems to be a central key player in the pathophysiology of this disease.

A 74-year-old male patient presented with progressive anorexia, cholestatic liver function tests, and a diffuse enlarged pancreas suggestive of a pancreatic carcinoma. There was a marked elevation of total immunoglobulin G4 (IgG4) in serum. Further investigation led to the diagnosis of IgG4-related sclerosing disease with involvement of the pancreas, retroperitoneal fibrosis, and bilateral focal nephritis. To our knowledge, this is the first report on these 3 clinical entities occurring in the same patient.A short review of the literature concerning autoimmune pancreatitis and retroperitoneal fibrosis is made, with special interest to the concept of IgG4-related pathology. This systemic disease can have several clinical manifestations: IgG4-positivity not only can be found in the pancreas, but also at the level of extrahepatic biliary ducts, gallbladder, salivary glands, retroperitoneal tissue, kidneys, ureters, and lymph nodes. Although further investigation is required to determine its exact pathophysiologic role, IgG4 seems to be an important key player.

Three patients with carcinoid tumors of the ileum are presented; two had severe intestinal ischemia, one with infarction of the small intestine. In all three cases, histopathological examination revealed elastic vascular sclerosis (EVS) in the mesenteric blood vessels. Intestinal ischemia in the presence of a carcinoid tumor is probably due to a combination of tumoral secretion products, vascular changes, mesenterial retraction and nodal involvement. Selective superior mesenteric artery arteriography is diagnostic. All the reported carcinoid tumors with ischemic manifestations are ileal and invaded the mesentery or had positive nodes or metastases; two-thirds had EVS, and one-third mesenterial vascular luminal narrowing. Intestinal ischemia may be the underlying cause of vague symptoms in patients with a carcinoid tumor. This tumor may be small and must be looked for during laparotomy, mild intestinal ischemia or mesenterial thickening are important signs. Early resection can prevent intestinal complications. An aggressive attitude, including debulking of metastases, is justifiable.

Two cases of reversible cholestatic hepatitis after treatment with an amoxycillin/clavulanic acid preparation (Augmentin) are described.

The underlying mechanism of the occurrence of a downward phase V at the end of a bolus washout curve was investigated in three healthy subjects. Phase V appeared not to originate from apical zones with low concentration of tracer gas but from dependent lung zones, which were not pathological. Indeed: 1) a reversed, upward, terminal slope was obtained when the bolus had been directed to the lung base by imposing a transition of the body through 180 degrees between inspiration and expiration or by inhaling a bolus close to TLC; 2) phase V was also present on N2 washout curves and, thus, originated from zones with smaller RV/TLC than the apical ones. Phase V increased with flow rate.