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1. Multiple, random spot urine sampling for estimating urinary sodium excretion

Author

Ardissino, Gianluigi, Vergori, Antonio, Vergori, Cesare, Martelli, Laura, Daccò, Valeria, Villa, Maria Cristina, Masciani, Martino, Monzani, Alice, Salice, Patrizia, Ghiglia, Silvia, Perrone, Michela, Capone, Valentina, Mancuso, Maria Cristina, Giussani, Antenore, Pieri, Giovanni Raimondo, Bosco, Annalisa, Brambilla, Marta, Romano, Roberto, Rotondo, Stefania, and Buzzetti, Roberto

Published
2022
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4. Fluid intake and blood pressure in children

Author

Ardissino, Gianluigi, primary, Perrone, Michela, additional, Ghiglia, Silvia, additional, Salice, Patrizia, additional, Tel, Francesca, additional, Dardi, Elena, additional, Bollani, Tiziana, additional, Mezzopane, Antonella, additional, Capone, Valentina, additional, Ardissino, Maddalena, additional, Vergori, Antonio, additional, Piantanida, Sandra, additional, Di Michele, Silvia, additional, Tchana, Bertrand, additional, Filippucci, Lucia, additional, De Luca, Francesco, additional, Consonni, Dario, additional, and Buzzetti, Roberto, additional

Published
2021
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5. Multiple, random spot urine sampling for estimating urinary sodium excretion

Author

Ardissino, Gianluigi, primary, Vergori, Antonio, additional, Vergori, Cesare, additional, Martelli, Laura, additional, Daccò, Valeria, additional, Villa, Maria Cristina, additional, Masciani, Martino, additional, Monzani, Alice, additional, Salice, Patrizia, additional, Ghiglia, Silvia, additional, Perrone, Michela, additional, Capone, Valentina, additional, Mancuso, Maria Cristina, additional, Giussani, Antenore, additional, Pieri, Giovanni Raimondo, additional, Bosco, Annalisa, additional, Brambilla, Marta, additional, Romano, Roberto, additional, Rotondo, Stefania, additional, and Buzzetti, Roberto, additional

Published
2021
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6. Updates in pediatric nephrology: relevant knowledge for the adult nephrologist

Author

Edefonti, Alberto, Vergori, Antonio, Montini, Giovanni, Emma, Francesco, Edefonti, Alberto, Vergori, Antonio, Montini, Giovanni, and Emma, Francesco

Abstract

Examples of innovative research in pediatric nephrology include: a) the typically pediatric field of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT), which has benefited from the discovery of numerous gene mutations responsible for the various malformations and the demonstration of the congenital origin of most of the renal damage, resulting in a decrease of invasive imaging, antibiotic prophylaxis and surgery; b) the approach to glomerular diseases that appear in childhood, like idiopathic nephrotic syndrome (INS), IgA nephropathy (IgAN) and C3 glomerulopathies (C3G). B and T lymphocyte disregulations and molecular podocyte alterations of immunological and genetic origin have been described in INS as main determinants of proteinuria. In IgAN, the discovery of an abnormal IgA glycosilation in the mucosal B cells has driven to new trials with Budesonide and Sparsentan and to innovative therapies, like atacicept. A new classification of C3G has been proposed after the description of genetic mutations of factors inhibiting activation of the alternative complement pathway, and monoclonal anti-C5 antibody Eculizumab has consequently entered the therapeutic armamentarium; c) the initial attempts at gene therapy, with promising results obtained in Alport syndrome, nephropathic cystinosis and Dent syndrome. Moreover, a clear example of precision medicine is represented by the refinement of the dosage of Eculizumab in the treatment of atypical HUS, while slow-medicine recommendations exist for common clinical conditions, like urinary tract infections, microscopic hematuria and proteinuria. &nbsp, Examples of innovative research in pediatric nephrology include: a) the typically pediatric field of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT), which has benefited from the discovery of numerous gene mutations responsible for the various malformations and the demonstration of the congenital origin of most of the renal damage, resulting in a decrease of invasive imaging, antibiotic prophylaxis and surgery; b) the approach to glomerular diseases that appear in childhood, like idiopathic nephrotic syndrome (INS), IgA nephropathy (IgAN) and C3 glomerulopathies (C3G). B and T lymphocyte disregulations and molecular podocyte alterations of immunological and genetic origin have been described in INS as main determinants of proteinuria. In IgAN, the discovery of an abnormal IgA glycosilation in the mucosal B cells has driven to new trials with Budesonide and Sparsentan and to innovative therapies, like atacicept. A new classification of C3G has been proposed after the description of genetic mutations of factors inhibiting activation of the alternative complement pathway, and monoclonal anti-C5 antibody Eculizumab has consequently entered the therapeutic armamentarium; c) the initial attempts at gene therapy, with promising results obtained in Alport syndrome, nephropathic cystinosis and Dent syndrome. Moreover, a clear example of precision medicine is represented by the refinement of the dosage of Eculizumab in the treatment of atypical HUS, while slow-medicine recommendations exist for common clinical conditions, like urinary tract infections, microscopic hematuria and proteinuria. &nbsp

Published
2021

8. Fluid Intake and Blood Pressure in Children. The Spa Project

Author

Ardissino, Gianluigi, primary, Perrone, Michela, additional, Ghiglia, Silvia, additional, Salice, Patrizia, additional, Tel, Francesca, additional, Dardi, Elena, additional, Bollani, Tiziana, additional, Mezzopane, Antonella, additional, Capone, Valentina, additional, Ardissino, Maddalena, additional, Vergori, Antonio, additional, Piantanida, Sandra, additional, Di Michele, Silvia, additional, Tchana, Bertrand, additional, Filippucci, Lucia, additional, De Luca, Francesco Letterio, additional, Consonni, Dario, additional, Buzzetti, Roberto, additional, and Group, SPA Project, additional

Published
2021
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10. Fluid intake and blood pressure in children: the Salus per Aquam project.

Author

Ardissino, Gianluigi, Perrone, Michela, Ghiglia, Silvia, Salice, Patrizia, Tel, Francesca, Dardi, Elena, Bollani, Tiziana, Mezzopane, Antonella, Capone, Valentina, Ardissino, Maddalena, Vergori, Antonio, Piantanida, Sandra, Di Michele, Silvia, Tchana, Bertrand, Filippucci, Lucia, De Luca, Francesco, Consonni, Dario, Buzzetti, Roberto, and SPA Project

Published
2022
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11. Disseminated Mycobacterium Avium Infection in a Child with Complete Interferon-γ Receptor 1 Deficiency due to Compound Heterozygosis of IFNGR1 for a Subpolymorphic Copy Number Variation and a Novel Splice-Site Variant

Author

Bossi, Grazia, additional, Errichiello, Edoardo, additional, Zuffardi, Orsetta, additional, Marone, Piero, additional, Monzillo, Vincenzina, additional, Barbarini, Daniela, additional, Vergori, Antonio, additional, Bassi, Lorenzo Andrea, additional, Rispoli, Gaetana Anna, additional, De Amici, Mara, additional, and Zecca, Marco, additional

Published
2019
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12. Correlation among atherosclerosis, cardiac and respiratory function in subjects with cystic fibrosis

Author

Ciccone, Marco M., primary, Cortese, Francesca, additional, Gesualdo, Michele, additional, Scicchitano, Pietro, additional, Ricci, Gabriella, additional, Carbonara, Santa, additional, Milo, Michele, additional, Carbonara, Rosa, additional, Urbano, Flavia, additional, Cortese, Anna M., additional, Vergori, Antonio, additional, Manca, Antonio, additional, and Mappa, Luigi, additional

Published
2018
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14. Prevalence of SARS-CoV-2-IgG Antibodies in Children with CKD or Immunosuppression

Author

Morello, William, Mastrangelo, Antonio, Guzzo, Isabella, Cusinato, Lisa, Annicchiarico Petruzzelli, Luigi, Benevenuta, Chiara, Martelli, Laura, Dall’Amico, Roberto, Vianello, Federica Alessandra, Puccio, Giuseppe, Massella, Laura, Benetti, Elisa, Pecoraro, Carmine, Peruzzi, Licia, Montini, Giovanni, Peruzzi, Licia, Petruzzelli, Luigi Annicchiarico, Becherucci, Francesca, Benetti, Elisa, Benevenuta, Chiara, Brugnara, Milena, Casadio, Luca, Chimenz, Roberto, Conti, Giovanni, Corrado, Ciro, D’Agostino, Viviana, Dall’Amico, Roberto, Gianoglio, Bruno, Giordano, Mario, Gualeni, Chiara, Guarino, Stefano, Guzzo, Isabella, La Manna, Angela, La Scola, Claudio, Martelli, Laura, Massella, Laura, Mastrangelo, Antonio, Materassi, Marco, Montini, Giovanni, Morello, William, Pani, Antonello, Papalia, Teresa, Pasini, Andrea, Pecoraro, Carmine, Pelliccia, Piernicola, Pennesi, Marco, Pugliese, Fabrizio, Ratsch, Ilse Maria, Romagnani, Paola, Roperto, Rosa Maria, Tamburello, Chiara, Vergine, Gianluca, Vergori, Antonio, Vianello, Federica Alessandra, and Vidal, Enrico

Published
2021
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