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1. KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Author: Schumann, Gunter, Liu, Chunyu, O'Reilly, Paul, Gao, He, Song, Parkyong, Xu, Bing, Ruggeri, Barbara, Amin, Najaf, Jia, Tianye, Preis, Sarah, Segura Lepe, Marcelo, Akira, Shizuo, Barbieri, Caterina, Baumeister, Sebastian, Cauchi, Stephane, Clarke, Toni-Kim, Enroth, Stefan, Fischer, Krista, Hällfors, Jenni, Harris, Sarah E, Hieber, Saskia, Hofer, Edith, Hottenga, Jouke-Jan, Johansson, Åsa, Joshi, Peter K, Kaartinen, Niina, Laitinen, Jaana, Lemaitre, Rozenn, Loukola, Anu, Luan, Jian'an, Lyytikäinen, Leo-Pekka, Mangino, Massimo, Manichaikul, Ani, Mbarek, Hamdi, Milaneschi, Yuri, Moayyeri, Alireza, Mukamal, Kenneth, Nelson, Christopher, Nettleton, Jennifer, Partinen, Eemil, Rawal, Rajesh, Robino, Antonietta, Rose, Lynda, Sala, Cinzia, Satoh, Takashi, Schmidt, Reinhold, Schraut, Katharina, Scott, Robert, Smith, Albert Vernon, Starr, John M, Teumer, Alexander, Trompet, Stella, Uitterlinden, André G, Venturini, Cristina, Vergnaud, Anne-Claire, Verweij, Niek, Vitart, Veronique, Vuckovic, Dragana, Wedenoja, Juho, Yengo, Loic, Yu, Bing, Zhang, Weihua, Zhao, Jing Hua, Boomsma, Dorret I, Chambers, John, Chasman, Daniel I, Daniela, Toniolo, de Geus, Eco, Deary, Ian, Eriksson, Johan G, Esko, Tõnu, Eulenburg, Volker, Franco, Oscar H, Froguel, Philippe, Gieger, Christian, Grabe, Hans J, Gudnason, Vilmundur, Gyllensten, Ulf, Harris, Tamara B, Hartikainen, Anna-Liisa, Heath, Andrew C, Hocking, Lynne, Hofman, Albert, Huth, Cornelia, Jarvelin, Marjo-Riitta, Jukema, J Wouter, Kaprio, Jaakko, Kooner, Jaspal S, Kutalik, Zoltan, Lahti, Jari, Langenberg, Claudia, Lehtimäki, Terho, Liu, Yongmei, Madden, Pamela AF, Martin, Nicholas, Morrison, Alanna, Penninx, Brenda, Pirastu, Nicola, Psaty, Bruce, and Raitakari, Olli
Subjects: Biological Psychology, Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Psychology, Alcoholism, Alcohol Use and Health, Genetics, Basic Behavioral and Social Science, Substance Misuse, Liver Disease, Behavioral and Social Science, Digestive Diseases, Neurosciences, Cardiovascular, Cancer, Oral and gastrointestinal, Stroke, Good Health and Well Being, Alcohol Drinking, Animals, Behavior, Animal, Brain, Emotions, Female, Fibroblast Growth Factors, Genome-Wide Association Study, Humans, Klotho Proteins, Liver, Male, Membrane Proteins, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Polymorphism, Single Nucleotide, alcohol consumption, human, beta-Klotho, FGF21, mouse model, β-Klotho
Abstract: Excessive alcohol consumption is a major public health problem worldwide. Although drinking habits are known to be inherited, few genes have been identified that are robustly linked to alcohol drinking. We conducted a genome-wide association metaanalysis and replication study among >105,000 individuals of European ancestry and identified β-Klotho (KLB) as a locus associated with alcohol consumption (rs11940694; P = 9.2 × 10-12). β-Klotho is an obligate coreceptor for the hormone FGF21, which is secreted from the liver and implicated in macronutrient preference in humans. We show that brain-specific β-Klotho KO mice have an increased alcohol preference and that FGF21 inhibits alcohol drinking by acting on the brain. These data suggest that a liver-brain endocrine axis may play an important role in the regulation of alcohol drinking behavior and provide a unique pharmacologic target for reducing alcohol consumption.
Published: 2016

2. Main nutrient patterns are associated with prospective weight change in adults from 10 European countries

Author: Freisling, Heinz, Pisa, Pedro T, Ferrari, Pietro, Byrnes, Graham, Moskal, Aurelie, Dahm, Christina C, Vergnaud, Anne-Claire, Boutron-Ruault, Marie-Christine, Fagherazzi, Guy, Cadeau, Claire, Kühn, Tilman, Neamat-Allah, Jasmine, Buijsse, Brian, Boeing, Heiner, Halkjær, Jytte, Tjonneland, Anne, Hansen, Camilla P, Quirós, J Ramón, Travier, Noémie, Molina-Montes, Esther, Amiano, Pilar, Huerta, José M, Barricarte, Aurelio, Khaw, Kay-Tee, Wareham, Nicholas, Key, Tim J, Romaguera, Dora, Lu, Yunxia, Lassale, Camille M, Naska, Androniki, Orfanos, Philippos, Trichopoulou, Antonia, Masala, Giovanna, Pala, Valeria, Berrino, Franco, Tumino, Rosario, Ricceri, Fulvio, de Magistris, Maria Santucci, Bueno-de-Mesquita, H Bas, Ocké, Marga C, Sonestedt, Emily, Ericson, Ulrika, Johansson, Mattias, Skeie, Guri, Weiderpass, Elisabete, Braaten, Tonje, Peeters, Petra HM, and Slimani, Nadia
Subjects: Public Health, Biomedical and Clinical Sciences, Nutrition and Dietetics, Health Sciences, Clinical Research, Prevention, Nutrition, Metabolic and endocrine, Adult, Aged, Ascorbic Acid, Calcium, Dietary, Diet, Dietary Fiber, Dietary Proteins, Europe, Female, Folic Acid, Follow-Up Studies, Humans, Linear Models, Male, Middle Aged, Nutrition Assessment, Phosphorus, Dietary, Prospective Studies, Riboflavin, Surveys and Questionnaires, Weight Gain, beta Carotene, Dietary patterns, Energy balance, Nutrients, Obesity, Public health, Weight gain, Nutrition & Dietetics, Nutrition and dietetics, Epidemiology
Abstract: PurposeVarious food patterns have been associated with weight change in adults, but it is unknown which combinations of nutrients may account for such observations. We investigated associations between main nutrient patterns and prospective weight change in adults.MethodsThis study includes 235,880 participants, 25-70 years old, recruited between 1992 and 2000 in 10 European countries. Intakes of 23 nutrients were estimated from country-specific validated dietary questionnaires using the harmonized EPIC Nutrient DataBase. Four nutrient patterns, explaining 67 % of the total variance of nutrient intakes, were previously identified from principal component analysis. Body weight was measured at recruitment and self-reported 5 years later. The relationship between nutrient patterns and annual weight change was examined separately for men and women using linear mixed models with random effect according to center controlling for confounders.ResultsMean weight gain was 460 g/year (SD 950) and 420 g/year (SD 940) for men and women, respectively. The annual differences in weight gain per one SD increase in the pattern scores were as follows: principal component (PC) 1, characterized by nutrients from plant food sources, was inversely associated with weight gain in men (-22 g/year; 95 % CI -33 to -10) and women (-18 g/year; 95 % CI -26 to -11). In contrast, PC4, characterized by protein, vitamin B2, phosphorus, and calcium, was associated with a weight gain of +41 g/year (95 % CI +2 to +80) and +88 g/year (95 % CI +36 to +140) in men and women, respectively. Associations with PC2, a pattern driven by many micro-nutrients, and with PC3, a pattern driven by vitamin D, were less consistent and/or non-significant.ConclusionsWe identified two main nutrient patterns that are associated with moderate but significant long-term differences in weight gain in adults.
Published: 2016

3. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

Author: Tajuddin, Salman M, Schick, Ursula M, Eicher, John D, Chami, Nathalie, Giri, Ayush, Brody, Jennifer A, Hill, W David, Kacprowski, Tim, Li, Jin, Lyytikäinen, Leo-Pekka, Manichaikul, Ani, Mihailov, Evelin, O’Donoghue, Michelle L, Pankratz, Nathan, Pazoki, Raha, Polfus, Linda M, Smith, Albert Vernon, Schurmann, Claudia, Vacchi-Suzzi, Caterina, Waterworth, Dawn M, Evangelou, Evangelos, Yanek, Lisa R, Burt, Amber, Chen, Ming-Huei, van Rooij, Frank JA, Floyd, James S, Greinacher, Andreas, Harris, Tamara B, Highland, Heather M, Lange, Leslie A, Liu, Yongmei, Mägi, Reedik, Nalls, Mike A, Mathias, Rasika A, Nickerson, Deborah A, Nikus, Kjell, Starr, John M, Tardif, Jean-Claude, Tzoulaki, Ioanna, Edwards, Digna R Velez, Wallentin, Lars, Bartz, Traci M, Becker, Lewis C, Denny, Joshua C, Raffield, Laura M, Rioux, John D, Friedrich, Nele, Fornage, Myriam, Gao, He, Hirschhorn, Joel N, Liewald, David CM, Rich, Stephen S, Uitterlinden, Andre, Bastarache, Lisa, Becker, Diane M, Boerwinkle, Eric, de Denus, Simon, Bottinger, Erwin P, Hayward, Caroline, Hofman, Albert, Homuth, Georg, Lange, Ethan, Launer, Lenore J, Lehtimäki, Terho, Lu, Yingchang, Metspalu, Andres, O’Donnell, Chris J, Quarells, Rakale C, Richard, Melissa, Torstenson, Eric S, Taylor, Kent D, Vergnaud, Anne-Claire, Zonderman, Alan B, Crosslin, David R, Deary, Ian J, Dörr, Marcus, Elliott, Paul, Evans, Michele K, Gudnason, Vilmundur, Kähönen, Mika, Psaty, Bruce M, Rotter, Jerome I, Slater, Andrew J, Dehghan, Abbas, White, Harvey D, Ganesh, Santhi K, Loos, Ruth JF, Esko, Tõnu, Faraday, Nauder, Wilson, James G, Cushman, Mary, Johnson, Andrew D, Edwards, Todd L, Zakai, Neil A, Lettre, Guillaume, Reiner, Alex P, and Auer, Paul L
Subjects: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Immunology, Hematology, Human Genome, Stem Cell Research, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Inflammatory and immune system, Blood Cell Count, Exome, Genetic Loci, Genetic Pleiotropy, Genome-Wide Association Study, Humans, Immune System Diseases, Leukocytes, Quality Control, Medical and Health Sciences, Genetics & Heredity, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract: White blood cells play diverse roles in innate and adaptive immunity. Genetic association analyses of phenotypic variation in circulating white blood cell (WBC) counts from large samples of otherwise healthy individuals can provide insights into genes and biologic pathways involved in production, differentiation, or clearance of particular WBC lineages (myeloid, lymphoid) and also potentially inform the genetic basis of autoimmune, allergic, and blood diseases. We performed an exome array-based meta-analysis of total WBC and subtype counts (neutrophils, monocytes, lymphocytes, basophils, and eosinophils) in a multi-ancestry discovery and replication sample of ∼157,622 individuals from 25 studies. We identified 16 common variants (8 of which were coding variants) associated with one or more WBC traits, the majority of which are pleiotropically associated with autoimmune diseases. Based on functional annotation, these loci included genes encoding surface markers of myeloid, lymphoid, or hematopoietic stem cell differentiation (CD69, CD33, CD87), transcription factors regulating lineage specification during hematopoiesis (ASXL1, IRF8, IKZF1, JMJD1C, ETS2-PSMG1), and molecules involved in neutrophil clearance/apoptosis (C10orf54, LTA), adhesion (TNXB), or centrosome and microtubule structure/function (KIF9, TUBD1). Together with recent reports of somatic ASXL1 mutations among individuals with idiopathic cytopenias or clonal hematopoiesis of undetermined significance, the identification of a common regulatory 3' UTR variant of ASXL1 suggests that both germline and somatic ASXL1 mutations contribute to lower blood counts in otherwise asymptomatic individuals. These association results shed light on genetic mechanisms that regulate circulating WBC counts and suggest a prominent shared genetic architecture with inflammatory and autoimmune diseases.
Published: 2016

4. Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Author: Eicher, John D, Chami, Nathalie, Kacprowski, Tim, Nomura, Akihiro, Chen, Ming-Huei, Yanek, Lisa R, Tajuddin, Salman M, Schick, Ursula M, Slater, Andrew J, Pankratz, Nathan, Polfus, Linda, Schurmann, Claudia, Giri, Ayush, Brody, Jennifer A, Lange, Leslie A, Manichaikul, Ani, Hill, W David, Pazoki, Raha, Elliot, Paul, Evangelou, Evangelos, Tzoulaki, Ioanna, Gao, He, Vergnaud, Anne-Claire, Mathias, Rasika A, Becker, Diane M, Becker, Lewis C, Burt, Amber, Crosslin, David R, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Hernesniemi, Jussi, Kähönen, Mika, Raitoharju, Emma, Mononen, Nina, Raitakari, Olli T, Lehtimäki, Terho, Cushman, Mary, Zakai, Neil A, Nickerson, Deborah A, Raffield, Laura M, Quarells, Rakale, Willer, Cristen J, Peloso, Gina M, Abecasis, Goncalo R, Liu, Dajiang J, Consortium, Global Lipids Genetics, Deloukas, Panos, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette, Consortium, CARDIoGRAM Exome, Consortium, Myocardial Infarction Genetics, Fornage, Myriam, Richard, Melissa, Tardif, Jean-Claude, Rioux, John D, Dube, Marie-Pierre, de Denus, Simon, Lu, Yingchang, Bottinger, Erwin P, Loos, Ruth JF, Smith, Albert Vernon, Harris, Tamara B, Launer, Lenore J, Gudnason, Vilmundur, Edwards, Digna R Velez, Torstenson, Eric S, Liu, Yongmei, Tracy, Russell P, Rotter, Jerome I, Rich, Stephen S, Highland, Heather M, Boerwinkle, Eric, Li, Jin, Lange, Ethan, Wilson, James G, Mihailov, Evelin, Mägi, Reedik, Hirschhorn, Joel, Metspalu, Andres, Esko, Tõnu, Vacchi-Suzzi, Caterina, Nalls, Mike A, Zonderman, Alan B, Evans, Michele K, Engström, Gunnar, Orho-Melander, Marju, Melander, Olle, O’Donoghue, Michelle L, Waterworth, Dawn M, Wallentin, Lars, White, Harvey D, Floyd, James S, Bartz, Traci M, Rice, Kenneth M, Psaty, Bruce M, Starr, JM, Liewald, David CM, Hayward, Caroline, and Deary, Ian J
Subjects: Biological Sciences, Genetics, Hematology, Clinical Research, Cardiovascular, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Blood, Blood Platelets, Exome, Female, Genetic Variation, Genome-Wide Association Study, Humans, Male, Mean Platelet Volume, Platelet Count, Global Lipids Genetics Consortium, CARDIoGRAM Exome Consortium, Myocardial Infarction Genetics Consortium, Medical and Health Sciences, Genetics & Heredity, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract: Platelet production, maintenance, and clearance are tightly controlled processes indicative of platelets' important roles in hemostasis and thrombosis. Platelets are common targets for primary and secondary prevention of several conditions. They are monitored clinically by complete blood counts, specifically with measurements of platelet count (PLT) and mean platelet volume (MPV). Identifying genetic effects on PLT and MPV can provide mechanistic insights into platelet biology and their role in disease. Therefore, we formed the Blood Cell Consortium (BCX) to perform a large-scale meta-analysis of Exomechip association results for PLT and MPV in 157,293 and 57,617 individuals, respectively. Using the low-frequency/rare coding variant-enriched Exomechip genotyping array, we sought to identify genetic variants associated with PLT and MPV. In addition to confirming 47 known PLT and 20 known MPV associations, we identified 32 PLT and 18 MPV associations not previously observed in the literature across the allele frequency spectrum, including rare large effect (FCER1A), low-frequency (IQGAP2, MAP1A, LY75), and common (ZMIZ2, SMG6, PEAR1, ARFGAP3/PACSIN2) variants. Several variants associated with PLT/MPV (PEAR1, MRVI1, PTGES3) were also associated with platelet reactivity. In concurrent BCX analyses, there was overlap of platelet-associated variants with red (MAP1A, TMPRSS6, ZMIZ2) and white (PEAR1, ZMIZ2, LY75) blood cell traits, suggesting common regulatory pathways with shared genetic architecture among these hematopoietic lineages. Our large-scale Exomechip analyses identified previously undocumented associations with platelet traits and further indicate that several complex quantitative hematological, lipid, and cardiovascular traits share genetic factors.
Published: 2016

5. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Author: Chami, Nathalie, Chen, Ming-Huei, Slater, Andrew J, Eicher, John D, Evangelou, Evangelos, Tajuddin, Salman M, Love-Gregory, Latisha, Kacprowski, Tim, Schick, Ursula M, Nomura, Akihiro, Giri, Ayush, Lessard, Samuel, Brody, Jennifer A, Schurmann, Claudia, Pankratz, Nathan, Yanek, Lisa R, Manichaikul, Ani, Pazoki, Raha, Mihailov, Evelin, Hill, W David, Raffield, Laura M, Burt, Amber, Bartz, Traci M, Becker, Diane M, Becker, Lewis C, Boerwinkle, Eric, Bork-Jensen, Jette, Bottinger, Erwin P, O’Donoghue, Michelle L, Crosslin, David R, de Denus, Simon, Dubé, Marie-Pierre, Elliott, Paul, Engström, Gunnar, Evans, Michele K, Floyd, James S, Fornage, Myriam, Gao, He, Greinacher, Andreas, Gudnason, Vilmundur, Hansen, Torben, Harris, Tamara B, Hayward, Caroline, Hernesniemi, Jussi, Highland, Heather M, Hirschhorn, Joel N, Hofman, Albert, Irvin, Marguerite R, Kähönen, Mika, Lange, Ethan, Launer, Lenore J, Lehtimäki, Terho, Li, Jin, Liewald, David CM, Linneberg, Allan, Liu, Yongmei, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mägi, Reedik, Mathias, Rasika A, Melander, Olle, Metspalu, Andres, Mononen, Nina, Nalls, Mike A, Nickerson, Deborah A, Nikus, Kjell, O’Donnell, Chris J, Orho-Melander, Marju, Pedersen, Oluf, Petersmann, Astrid, Polfus, Linda, Psaty, Bruce M, Raitakari, Olli T, Raitoharju, Emma, Richard, Melissa, Rice, Kenneth M, Rivadeneira, Fernando, Rotter, Jerome I, Schmidt, Frank, Smith, Albert Vernon, Starr, John M, Taylor, Kent D, Teumer, Alexander, Thuesen, Betina H, Torstenson, Eric S, Tracy, Russell P, Tzoulaki, Ioanna, Zakai, Neil A, Vacchi-Suzzi, Caterina, van Duijn, Cornelia M, van Rooij, Frank JA, Cushman, Mary, Deary, Ian J, Edwards, Digna R Velez, Vergnaud, Anne-Claire, Wallentin, Lars, Waterworth, Dawn M, White, Harvey D, Wilson, James G, and Zonderman, Alan B
Subjects: Epidemiology, Biological Sciences, Health Sciences, Genetics, Minority Health, Women's Health, Hematology, Clinical Research, Rare Diseases, Human Genome, Health Disparities, 2.1 Biological and endogenous factors, Metabolic and endocrine, Black or African American, Allelic Imbalance, Erythrocyte Indices, Erythrocytes, Erythropoiesis, Exome, Gene Frequency, Genetic Pleiotropy, Genetic Variation, Genotype, Hematocrit, Hemoglobins, Humans, Quantitative Trait Loci, Medical and Health Sciences, Genetics & Heredity, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract: Red blood cell (RBC) traits are important heritable clinical biomarkers and modifiers of disease severity. To identify coding genetic variants associated with these traits, we conducted meta-analyses of seven RBC phenotypes in 130,273 multi-ethnic individuals from studies genotyped on an exome array. After conditional analyses and replication in 27,480 independent individuals, we identified 16 new RBC variants. We found low-frequency missense variants in MAP1A (rs55707100, minor allele frequency [MAF] = 3.3%, p = 2 × 10(-10) for hemoglobin [HGB]) and HNF4A (rs1800961, MAF = 2.4%, p < 3 × 10(-8) for hematocrit [HCT] and HGB). In African Americans, we identified a nonsense variant in CD36 associated with higher RBC distribution width (rs3211938, MAF = 8.7%, p = 7 × 10(-11)) and showed that it is associated with lower CD36 expression and strong allelic imbalance in ex vivo differentiated human erythroblasts. We also identified a rare missense variant in ALAS2 (rs201062903, MAF = 0.2%) associated with lower mean corpuscular volume and mean corpuscular hemoglobin (p < 8 × 10(-9)). Mendelian mutations in ALAS2 are a cause of sideroblastic anemia and erythropoietic protoporphyria. Gene-based testing highlighted three rare missense variants in PKLR, a gene mutated in Mendelian non-spherocytic hemolytic anemia, associated with HGB and HCT (SKAT p < 8 × 10(-7)). These rare, low-frequency, and common RBC variants showed pleiotropy, being also associated with platelet, white blood cell, and lipid traits. Our association results and functional annotation suggest the involvement of new genes in human erythropoiesis. We also confirm that rare and low-frequency variants play a role in the architecture of complex human traits, although their phenotypic effect is generally smaller than originally anticipated.
Published: 2016

6. Use of TETRA personal radios and sickness absence in the Airwave Health Monitoring Study of the British police forces

Author: Elliott, Paul, Aresu, Maria, Gao, He, Vergnaud, Anne-Claire, Heard, Andy, McRobie, Dennis, Spear, Jeanette, Singh, Deepa, Kongsgård, Håvard Wahl, Mbema, Catherine, and Muller, David C.
Published: 2019
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7. Estimation of TETRA radio use in the Airwave Health Monitoring Study of the British police forces

Author: Vergnaud, Anne-Claire, Aresu, Maria, Kongsgård, Håvard Wahl, McRobie, Dennis, Singh, Deepa, Spear, Jeanette, Heard, Andy, Gao, He, Carpenter, James R., and Elliott, Paul
Published: 2018
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8. Personal radio use and cancer risks among 48,518 British police officers and staff from the Airwave Health Monitoring Study

Author: Gao, He, Aresu, Maria, Vergnaud, Anne-Claire, McRobie, Dennis, Spear, Jeanette, Heard, Andy, Kongsgård, Håvard Wahl, Singh, Deepa, Muller, David C., and Elliott, Paul
Published: 2019
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9. A cross-sectional investigation into the occupational and socio-demographic characteristics of British police force employees reporting a dietary pattern associated with cardiometabolic risk: findings from the Airwave Health Monitoring Study

Author: Gibson, Rachel, Eriksen, Rebeca, Singh, Deepa, Vergnaud, Anne-Claire, Heard, Andrew, Chan, Queenie, Elliott, Paul, and Frost, Gary
Published: 2018
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10. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Author: Evangelou, Evangelos, Warren, Helen R., Mosen-Ansorena, David, Mifsud, Borbala, Pazoki, Raha, Gao, He, Ntritsos, Georgios, Dimou, Niki, Cabrera, Claudia P., Karaman, Ibrahim, Ng, Fu Liang, Evangelou, Marina, Witkowska, Katarzyna, Tzanis, Evan, Hellwege, Jacklyn N., Giri, Ayush, Velez Edwards, Digna R., Sun, Yan V., Cho, Kelly, Gaziano, J. Michael, Wilson, Peter W. F., Tsao, Philip S., Kovesdy, Csaba P., Esko, Tonu, Mägi, Reedik, Milani, Lili, Almgren, Peter, Boutin, Thibaud, Debette, Stéphanie, Ding, Jun, Giulianini, Franco, Holliday, Elizabeth G., Jackson, Anne U., Li-Gao, Ruifang, Lin, Wei-Yu, Luan, Jian’an, Mangino, Massimo, Oldmeadow, Christopher, Prins, Bram Peter, Qian, Yong, Sargurupremraj, Muralidharan, Shah, Nabi, Surendran, Praveen, Thériault, Sébastien, Verweij, Niek, Willems, Sara M., Zhao, Jing-Hua, Amouyel, Philippe, Connell, John, de Mutsert, Renée, Doney, Alex S. F., Farrall, Martin, Menni, Cristina, Morris, Andrew D., Noordam, Raymond, Paré, Guillaume, Poulter, Neil R., Shields, Denis C., Stanton, Alice, Thom, Simon, Abecasis, Gonçalo, Amin, Najaf, Arking, Dan E., Ayers, Kristin L., Barbieri, Caterina M., Batini, Chiara, Bis, Joshua C., Blake, Tineka, Bochud, Murielle, Boehnke, Michael, Boerwinkle, Eric, Boomsma, Dorret I., Bottinger, Erwin P., Braund, Peter S., Brumat, Marco, Campbell, Archie, Campbell, Harry, Chakravarti, Aravinda, Chambers, John C., Chauhan, Ganesh, Ciullo, Marina, Cocca, Massimiliano, Collins, Francis, Cordell, Heather J., Davies, Gail, de Borst, Martin H., de Geus, Eco J., Deary, Ian J., Deelen, Joris, Del Greco M., Fabiola, Demirkale, Cumhur Yusuf, Dörr, Marcus, Ehret, Georg B., Elosua, Roberto, Enroth, Stefan, Erzurumluoglu, A. Mesut, Ferreira, Teresa, Frånberg, Mattias, Franco, Oscar H., Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Gieger, Christian, Girotto, Giorgia, Goel, Anuj, Gow, Alan J., Gudnason, Vilmundur, Guo, Xiuqing, Gyllensten, Ulf, Hamsten, Anders, Harris, Tamara B., Harris, Sarah E., Hartman, Catharina A., Havulinna, Aki S., Hicks, Andrew A., Hofer, Edith, Hofman, Albert, Hottenga, Jouke-Jan, Huffman, Jennifer E., Hwang, Shih-Jen, Ingelsson, Erik, James, Alan, Jansen, Rick, Jarvelin, Marjo-Riitta, Joehanes, Roby, Johansson, Åsa, Johnson, Andrew D., Joshi, Peter K., Jousilahti, Pekka, Jukema, J. Wouter, Jula, Antti, Kähönen, Mika, Kathiresan, Sekar, Keavney, Bernard D., Khaw, Kay-Tee, Knekt, Paul, Knight, Joanne, Kolcic, Ivana, Kooner, Jaspal S., Koskinen, Seppo, Kristiansson, Kati, Kutalik, Zoltan, Laan, Maris, Larson, Marty, Launer, Lenore J., Lehne, Benjamin, Lehtimäki, Terho, Liewald, David C. M., Lin, Li, Lind, Lars, Lindgren, Cecilia M., Liu, YongMei, Loos, Ruth J. F., Lopez, Lorna M., Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mahajan, Anubha, Mamasoula, Chrysovalanto, Marrugat, Jaume, Marten, Jonathan, Milaneschi, Yuri, Morgan, Anna, Morris, Andrew P., Morrison, Alanna C., Munson, Peter J., Nalls, Mike A., Nandakumar, Priyanka, Nelson, Christopher P., Niiranen, Teemu, Nolte, Ilja M., Nutile, Teresa, Oldehinkel, Albertine J., Oostra, Ben A., O’Reilly, Paul F., Org, Elin, Padmanabhan, Sandosh, Palmas, Walter, Palotie, Aarno, Pattie, Alison, Penninx, Brenda W. J. H., Perola, Markus, Peters, Annette, Polasek, Ozren, Pramstaller, Peter P., Nguyen, Quang Tri, Raitakari, Olli T., Ren, Meixia, Rettig, Rainer, Rice, Kenneth, Ridker, Paul M., Ried, Janina S., Riese, Harriëtte, Ripatti, Samuli, Robino, Antonietta, Rose, Lynda M., Rotter, Jerome I., Rudan, Igor, Ruggiero, Daniela, Saba, Yasaman, Sala, Cinzia F., Salomaa, Veikko, Samani, Nilesh J., Sarin, Antti-Pekka, Schmidt, Reinhold, Schmidt, Helena, Shrine, Nick, Siscovick, David, Smith, Albert V., Snieder, Harold, Sõber, Siim, Sorice, Rossella, Starr, John M., Stott, David J., Strachan, David P., Strawbridge, Rona J., Sundström, Johan, Swertz, Morris A., Taylor, Kent D., Teumer, Alexander, Tobin, Martin D., Tomaszewski, Maciej, Toniolo, Daniela, Traglia, Michela, Trompet, Stella, Tuomilehto, Jaakko, Tzourio, Christophe, Uitterlinden, André G., Vaez, Ahmad, van der Most, Peter J., van Duijn, Cornelia M., Vergnaud, Anne-Claire, Verwoert, Germaine C., Vitart, Veronique, Völker, Uwe, Vollenweider, Peter, Vuckovic, Dragana, Watkins, Hugh, Wild, Sarah H., Willemsen, Gonneke, Wilson, James F., Wright, Alan F., Yao, Jie, Zemunik, Tatijana, Zhang, Weihua, Attia, John R., Butterworth, Adam S., Chasman, Daniel I., Conen, David, Cucca, Francesco, Danesh, John, Hayward, Caroline, Howson, Joanna M. M., Laakso, Markku, Lakatta, Edward G., Langenberg, Claudia, Melander, Olle, Mook-Kanamori, Dennis O., Palmer, Colin N. A., Risch, Lorenz, Scott, Robert A., Scott, Rodney J., Sever, Peter, Spector, Tim D., van der Harst, Pim, Wareham, Nicholas J., Zeggini, Eleftheria, Levy, Daniel, Munroe, Patricia B., Newton-Cheh, Christopher, Brown, Morris J., Metspalu, Andres, Hung, Adriana M., O’Donnell, Christopher J., Edwards, Todd L., Psaty, Bruce M., Tzoulaki, Ioanna, Barnes, Michael R., Wain, Louise V., Elliott, Paul, Caulfield, Mark J., and the Million Veteran Program
Published: 2018
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11. Validation of objective records and misreporting of personal radio use in a cohort of British Police forces (the Airwave Health Monitoring Study)

Author: Vergnaud, Anne-Claire, Aresu, Maria, McRobie, Dennis, Singh, Deepa, Spear, Jeanette, Heard, Andy, and Elliott, Paul
Published: 2016
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12. The Airwave Health Monitoring Study of police officers and staff in Great Britain: Rationale, design and methods

Author: Elliott, Paul, Vergnaud, Anne-Claire, Singh, Deepa, Neasham, David, Spear, Jeanette, and Heard, Andy
Published: 2014
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13. Adherence to the World Cancer Research Fund/American Institute for Cancer Research guidelines and risk of death in Europe: results from the European Prospective Investigation into Nutrition and Cancer cohort study

Author: Vergnaud, Anne-Claire, Romaguera, Dora, Peeters, Petra H, van Gils, Carla H, Chan, Doris SM, Romieu, Isabelle, Freisling, Heinz, Ferrari, Pietro, Clavel-Chapelon, Françoise, Fagherazzi, Guy, Dartois, Laureen, Li, Kuanrong, Tikk, Kaja, Bergmann, Manuela M, Boeing, Heiner, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Dahm, Christina C, Redondo, Maria Luisa, Agudo, Antonio, Sánchez, María-José, Amiano, Pilar, Chirlaque, María-Dolores, Ardanaz, Eva, Khaw, Kay-Tee, Wareham, Nick J, Crowe, Francesca, Trichopoulou, Antonia, Orfanos, Philippos, Trichopoulos, Dimitrios, Masala, Giovanna, Sieri, Sabina, Tumino, Rosario, Vineis, Paolo, Panico, Salvatore, Bueno-de-Mesquita, H Bas, Ros, Martine M, May, Anne, Wirfält, Elisabet, Sonestedt, Emily, Johansson, Ingegerd, Hallmans, Göran, Lund, Eiliv, Weiderpass, Elisabete, Parr, Christine L, Riboli, Elio, and Norat, Teresa
Published: 2013
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14. New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Author: Kraja, Aldi T., Cook, James P., Warren, Helen R., Surendran, Praveen, Liu, Chunyu, Evangelou, Evangelos, Manning, Alisa K., Grarup, Niels, Drenos, Fotios, Sim, Xueling, Smith, Albert Vernon, Amin, Najaf, Blakemore, Alexandra I.F., Bork-Jensen, Jette, Brandslund, Ivan, Farmaki, Aliki-Eleni, Fava, Cristiano, Ferreira, Teresa, Herzig, Karl-Heinz, Giri, Ayush, Giulianini, Franco, Grove, Megan L., Guo, Xiuqing, Harris, Sarah E., Have, Christian T., Havulinna, Aki S., Zhang, He, Jørgensen, Marit E., Käräjämäki, AnneMari, Kooperberg, Charles, Linneberg, Allan, Little, Louis, Liu, Yongmei, Bonnycastle, Lori L., Lu, Yingchang, Mägi, Reedik, Mahajan, Anubha, Malerba, Giovanni, Marioni, Riccardo E., Mei, Hao, Menni, Cristina, Morrison, Alanna C., Padmanabhan, Sandosh, Palmas, Walter, Poveda, Alaitz, Rauramaa, Rainer, Rayner, Nigel William, Riaz, Muhammad, Rice, Ken, Richard, Melissa A., Smith, Jennifer A., Southam, Lorraine, Stančáková, Alena, Stirrups, Kathleen E., Tragante, Vinicius, Tuomi, Tiinamaija, Tzoulaki, Ioanna, Varga, Tibor V., Weiss, Stefan, Yiorkas, Andrianos M., Young, Robin, Zhang, Weihua, Barnes, Michael R., Cabrera, Claudia P., Gao, He, Boehnke, Michael, Boerwinkle, Eric, Chambers, John C., Connell, John M., Christensen, Cramer K., de Boer, Rudolf A., Deary, Ian J., Dedoussis, George, Deloukas, Panos, Dominiczak, Anna F., Dörr, Marcus, Joehanes, Roby, Edwards, Todd L., Esko, Tõnu, Fornage, Myriam, Franceschini, Nora, Franks, Paul W., Gambaro, Giovanni, Groop, Leif, Hallmans, Göran, Hansen, Torben, Hayward, Caroline, Heikki, Oksa, Ingelsson, Erik, Tuomilehto, Jaakko, Jarvelin, Marjo-Riitta, Kardia, Sharon L.R., Karpe, Fredrik, Kooner, Jaspal S., Lakka, Timo A., Langenberg, Claudia, Lind, Lars, Loos, Ruth J.F., Laakso, Markku, McCarthy, Mark I., Melander, Olle, Mohlke, Karen L., Morris, Andrew P., Palmer, Colin N.A., Pedersen, Oluf, Polasek, Ozren, Poulter, Neil R., Province, Michael A., Psaty, Bruce M., Ridker, Paul M., Rotter, Jerome I., Rudan, Igor, Salomaa, Veikko, Samani, Nilesh J., Sever, Peter J., Skaaby, Tea, Stafford, Jeanette M., Starr, John M., van der Harst, Pim, van der Meer, Peter, van Duijn, Cornelia M., Vergnaud, Anne-Claire, Gudnason, Vilmundur, Wareham, Nicholas J., Wilson, James G., Willer, Cristen J., Witte, Daniel R., Zeggini, Eleftheria, Saleheen, Danish, Butterworth, Adam S., Danesh, John, Asselbergs, Folkert W., Wain, Louise V., Ehret, Georg B., Chasman, Daniel I., Caulfield, Mark J., Elliott, Paul, Lindgren, Cecilia M., Levy, Daniel, Newton-Cheh, Christopher, Munroe, Patricia B., and Howson, Joanna M.M.
Published: 2017
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15. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Author: Wain, Louise V., Vaez, Ahmad, Jansen, Rick, Joehanes, Roby, van der Most, Peter J., Erzurumluoglu, A. Mesut, O’Reilly, Paul F., Cabrera, Claudia P., Warren, Helen R., Rose, Lynda M., Verwoert, Germaine C., Hottenga, Jouke-Jan, Strawbridge, Rona J., Esko, Tonu, Arking, Dan E., Hwang, Shih-Jen, Guo, Xiuqing, Kutalik, Zoltan, Trompet, Stella, Shrine, Nick, Teumer, Alexander, Ried, Janina S., Bis, Joshua C., Smith, Albert V., Amin, Najaf, Nolte, Ilja M., Lyytikäinen, Leo-Pekka, Mahajan, Anubha, Wareham, Nicholas J., Hofer, Edith, Joshi, Peter K., Kristiansson, Kati, Traglia, Michela, Havulinna, Aki S., Goel, Anuj, Nalls, Mike A., Sõber, Siim, Vuckovic, Dragana, Luan, Jian’an, Del Greco M., Fabiola, Ayers, Kristin L., Marrugat, Jaume, Ruggiero, Daniela, Lopez, Lorna M., Niiranen, Teemu, Enroth, Stefan, Jackson, Anne U., Nelson, Christopher P., Huffman, Jennifer E., Zhang, Weihua, Marten, Jonathan, Gandin, Ilaria, Harris, Sarah E., Zemunik, Tatijana, Lu, Yingchang, Evangelou, Evangelos, Shah, Nabi, de Borst, Martin H., Mangino, Massimo, Prins, Bram P., Campbell, Archie, Li-Gao, Ruifang, Chauhan, Ganesh, Oldmeadow, Christopher, Abecasis, Gonçalo, Abedi, Maryam, Barbieri, Caterina M., Barnes, Michael R., Batini, Chiara, Beilby, John, Blake, Tineka, Boehnke, Michael, Bottinger, Erwin P., Braund, Peter S., Brown, Morris, Brumat, Marco, Campbell, Harry, Chambers, John C., Cocca, Massimiliano, Collins, Francis, Connell, John, Cordell, Heather J., Damman, Jeffrey J., Davies, Gail, de Geus, Eco J., de Mutsert, Renée, Deelen, Joris, Demirkale, Yusuf, Doney, Alex S.F., Dörr, Marcus, Farrall, Martin, Ferreira, Teresa, Frånberg, Mattias, Gao, He, Giedraitis, Vilmantas, Gieger, Christian, Giulianini, Franco, Gow, Alan J., Hamsten, Anders, Harris, Tamara B., Hofman, Albert, Holliday, Elizabeth G., Hui, Jennie, Jarvelin, Marjo-Riitta, Johansson, Åsa, Johnson, Andrew D., Jousilahti, Pekka, Jula, Antti, Kähönen, Mika, Kathiresan, Sekar, Khaw, Kay-Tee, Kolcic, Ivana, Koskinen, Seppo, Langenberg, Claudia, Larson, Marty, Launer, Lenore J., Lehne, Benjamin, Liewald, David C.M., Lin, Li, Lind, Lars, Mach, François, Mamasoula, Chrysovalanto, Menni, Cristina, Mifsud, Borbala, Milaneschi, Yuri, Morgan, Anna, Morris, Andrew D., Morrison, Alanna C., Munson, Peter J., Nandakumar, Priyanka, Nguyen, Quang Tri, Nutile, Teresa, Oldehinkel, Albertine J., Oostra, Ben A., Org, Elin, Padmanabhan, Sandosh, Palotie, Aarno, Paré, Guillaume, Pattie, Alison, Penninx, Brenda W.J.H., Poulter, Neil, Pramstaller, Peter P., Raitakari, Olli T., Ren, Meixia, Rice, Kenneth, Ridker, Paul M., Riese, Harriëtte, Ripatti, Samuli, Robino, Antonietta, Rotter, Jerome I., Rudan, Igor, Saba, Yasaman, Saint Pierre, Aude, Sala, Cinzia F., Sarin, Antti-Pekka, Schmidt, Reinhold, Scott, Rodney, Seelen, Marc A., Shields, Denis C., Siscovick, David, Sorice, Rossella, Stanton, Alice, Stott, David J., Sundström, Johan, Swertz, Morris, Taylor, Kent D., Thom, Simon, Tzoulaki, Ioanna, Tzourio, Christophe, Uitterlinden, André G., Völker, Uwe, Vollenweider, Peter, Wild, Sarah, Willemsen, Gonneke, Wright, Alan F., Yao, Jie, Thériault, Sébastien, Conen, David, Attia, John, Sever, Peter, Debette, Stéphanie, Mook-Kanamori, Dennis O., Zeggini, Eleftheria, Spector, Tim D., van der Harst, Pim, Palmer, Colin N.A., Vergnaud, Anne-Claire, Loos, Ruth J.F., Polasek, Ozren, Starr, John M., Girotto, Giorgia, Hayward, Caroline, Kooner, Jaspal S., Lindgren, Cecila M., Vitart, Veronique, Samani, Nilesh J., Tuomilehto, Jaakko, Gyllensten, Ulf, Knekt, Paul, Deary, Ian J., Ciullo, Marina, Elosua, Roberto, Keavney, Bernard D., Hicks, Andrew A., Scott, Robert A., Gasparini, Paolo, Laan, Maris, Liu, YongMei, Watkins, Hugh, Hartman, Catharina A., Salomaa, Veikko, Toniolo, Daniela, Perola, Markus, Wilson, James F., Schmidt, Helena, Zhao, Jing Hua, Lehtimäki, Terho, van Duijn, Cornelia M., Gudnason, Vilmundur, Psaty, Bruce M., Peters, Annette, Rettig, Rainer, James, Alan, Jukema, J. Wouter, Strachan, David P., Palmas, Walter, Metspalu, Andres, Ingelsson, Erik, Boomsma, Dorret I., Franco, Oscar H., Bochud, Murielle, Newton-Cheh, Christopher, Munroe, Patricia B., Elliott, Paul, Chasman, Daniel I., Chakravarti, Aravinda, Knight, Joanne, Morris, Andrew P., Levy, Daniel, Tobin, Martin D., Snieder, Harold, Caulfield, Mark J., and Ehret, Georg B.
Published: 2017
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16. Is concordance with World Cancer Research Fund/American Institute for Cancer Research guidelines for cancer prevention related to subsequent risk of cancer? Results from the EPIC study

Author: Romaguera, Dora, Vergnaud, Anne-Claire, Peeters, Petra H, van Gils, Carla H, Chan, Doris SM, Ferrari, Pietro, Romieu, Isabelle, Jenab, Mazda, Slimani, Nadia, Clavel-Chapelon, Françoise, Fagherazzi, Guy, Perquier, Florence, Kaaks, Rudolf, Teucher, Birgit, Boeing, Heiner, von Rüsten, Anne, Tjønneland, Anne, Olsen, Anja, Dahm, Christina C, Overvad, Kim, Quirós, José Ramón, Gonzalez, Carlos A, Sánchez, María José, Navarro, Carmen, Barricarte, Aurelio, Dorronsoro, Miren, Khaw, Kay-Tee, Wareham, Nicholas J, Crowe, Francesca L, Key, Timothy J, Trichopoulou, Antonia, Lagiou, Pagona, Bamia, Christina, Masala, Giovanna, Vineis, Paolo, Tumino, Rosario, Sieri, Sabina, Panico, Salvatore, May, Anne M, Bueno-de-Mesquita, H Bas, Büchner, Frederike L, Wirfält, Elisabet, Manjer, Jonas, Johansson, Ingegerd, Hallmans, Göran, Skeie, Guri, Benjaminsen Borch, Kristin, Parr, Christine L, Riboli, Elio, and Norat, Teresa
Published: 2012
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17. Fruit and vegetable consumption and prospective weight change in participants of the European Prospective Investigation into Cancer and Nutrition–Physical Activity, Nutrition, Alcohol, Cessation of Smoking, Eating Out of Home, and Obesity study

Author: Vergnaud, Anne-Claire, Norat, Teresa, Romaguera, Dora, Mouw, Traci, May, Anne M, Romieu, Isabelle, Freisling, Heinz, Slimani, Nadia, Boutron-Ruault, Marie-Christine, Clavel-Chapelon, Françoise, Morois, Sophie, Kaaks, Rudolf, Teucher, Birgit, Boeing, Heiner, Buijsse, Brian, Tjønneland, Anne, Halkjær, Jytte, Overvad, Kim, Jakobsen, Marianne Uhre, Rodríguez, Laudina, Agudo, Antonio, Sánchez, Maria-José, Amiano, Pilar, Huerta, José María, Gurrea, Aurelio Barricarte, Wareham, Nick, Khaw, Kay-Tee, Crowe, Francesca, Orfanos, Philippos, Naska, Androniki, Trichopoulou, Antonia, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Sacerdote, Carlotta, Mattiello, Amalia, Bueno-de-Mesquita, H Bas, van Duijnhoven, Fränzel JB, Drake, Isabel, Wirfält, Elisabet, Johansson, Ingegerd, Hallmans, Göran, Engeset, Dagrun, Braaten, Tonje, Parr, Christine L, Odysseos, Andreani, Riboli, Elio, and Peeters, Petra HM
Published: 2012
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18. Consumption of meat and fish and risk of lung cancer: results from the European Prospective Investigation into Cancer and Nutrition

Author: Linseisen, Jakob, Rohrmann, Sabine, Bueno-de-Mesquita, Bas, Büchner, Frederike L., Boshuizen, Hendriek C., Agudo, Antonio, Gram, Inger Torhild, Dahm, Christina C., Overvad, Kim, Egeberg, Rikke, Tjønneland, Anne, Boeing, Heiner, Steffen, Annika, Kaaks, Rudolf, Lukanova, Annekatrin, Berrino, Franco, Palli, Domenico, Panico, Salvatore, Tumino, Rosario, Ardanaz, Eva, Dorronsoro, Miren, Huerta, José-Maria, Rodríguez, Laudina, Sánchez, María-José, Rasmuson, Torgny, Hallmans, Göran, Manjer, Jonas, Wirfält, Elisabet, Engeset, Dagrun, Skeie, Guri, Katsoulis, Michael, Oikonomou, Eleni, Trichopoulou, Antonia, Peeters, Petra H. M., Khaw, Kay-Tee, Wareham, Nicholas, Allen, Naomi, Key, Tim, Brennan, Paul, Romieu, Isabelle, Slimani, Nadia, Vergnaud, Anne-Claire, Xun, Wei W., Vineis, Paolo, and Riboli, Elio
Published: 2011

19. Mediterranean dietary patterns and prospective weight change in participants of the EPIC-PANACEA project

Author: Romaguera, Dora, Norat, Teresa, Vergnaud, Anne-Claire, Mouw, Traci, May, Anne M, Agudo, Antonio, Buckland, Genevieve, Slimani, Nadia, Rinaldi, Sabina, Couto, Elisabeth, Clavel-Chapelon, Françoise, Boutron-Ruault, Marie-Christine, Cottet, Vanessa, Rohrmann, Sabine, Teucher, Birgit, Bergmann, Manuela, Boeing, Heiner, Tjønneland, Anne, Halkjaer, Jytte, Jakobsen, Marianne Uhre, Dahm, Christina C, Travier, Noemie, Rodriguez, Laudina, Sanchez, Maria José, Amiano, Pilar, Barricarte, Aurelio, Huerta, José María, Luan, Jian’an, Wareham, Nick, Key, Timothy J, Spencer, Elisabeth A, Orfanos, Philippos, Naska, Androniki, Trichopoulou, Antonia, Palli, Domenico, Agnoli, Claudia, Mattiello, Amalia, Tumino, Rosario, Vineis, Paolo, Bueno-de-Mesquita, H Bas, Büchner, Frederike L, Manjer, Jonas, Wirfält, Elisabet, Johansson, Ingegerd, Hellstrom, Veronica, Lund, Eiliv, Braaten, Toni, Engeset, Dagrun, Odysseos, Andreani, Riboli, Elio, and Peeters, Petra HM
Published: 2010
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20. Meat consumption and prospective weight change in participants of the EPIC-PANACEA study

Author: Vergnaud, Anne-Claire, Norat, Teresa, Romaguera, Dora, Mouw, Traci, May, Anne M, Travier, Noemie, Luan, Jian’an, Wareham, Nick, Slimani, Nadia, Rinaldi, Sabina, Couto, Elisabeth, Clavel-Chapelon, Françoise, Boutron-Ruault, Marie-Christine, Cottet, Vanessa, Palli, Domenico, Agnoli, Claudia, Panico, Salvatore, Tumino, Rosario, Vineis, Paolo, Agudo, Antonio, Rodriguez, Laudina, Sanchez, Maria Jose, Amiano, Pilar, Barricarte, Aurelio, Huerta, Jose Maria, Key, Timothy J, Spencer, Elisabeth A, Bueno-de-Mesquita, Bas, Büchner, Frederike L, Orfanos, Philippos, Naska, Androniki, Trichopoulou, Antonia, Rohrmann, Sabine, Hermann, Silke, Boeing, Heiner, Buijsse, Brian, Johansson, Ingegerd, Hellstrom, Veronica, Manjer, Jonas, Wirfält, Elisabet, Jakobsen, Marianne Uhre, Overvad, Kim, Tjonneland, Anne, Halkjaer, Jytte, Lund, Eiliv, Braaten, Tonje, Engeset, Dagrun, Odysseos, Andreani, Riboli, Elio, and Peeters, Petra HM
Published: 2010
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21. Low Total and Nonheme Iron Intakes Are Associated with a Greater Risk of Hypertension

Author: Galan, Pilar, Vergnaud, Anne-Claire, Tzoulaki, Ioanna, Buyck, Jean-François, Blacher, Jacques, Czernichow, Sébastien, and Hercberg, Serge
Published: 2010
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22. Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults

Author: Czernichow, Sébastien, Vergnaud, Anne-Claire, Galan, Pilar, Arnaud, Josiane, Favier, Alain, Faure, Henri, Huxley, Rachel, Hercberg, Serge, and Ahluwalia, Namanjeet
Published: 2009
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23. Healthy lifestyle and risk of breast cancer among postmenopausal women in the European Prospective Investigation into Cancer and Nutrition cohort study

Author: McKenzie, Fiona, Ferrari, Pietro, Freisling, Heinz, Chajès, Veronique, Rinaldi, Sabina, de Batlle, Jordi, Dahm, Christina C, Overvad, Kim, Baglietto, Laura, Dartois, Laureen, Dossus, Laure, Lagiou, Pagona, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Krogh, Vittorio, Panico, Salvatore, Tumino, Rosario, Rosso, Stefano, Bueno-de-Mesquita, B(as) H., May, Anne, Peeters, Petra H, Weiderpass, Elisabete, Buckland, Genevieve, Sanchez, Maria-Jose, Navarro, Carmen, Ardanaz, Eva, Andersson, Anne, Sund, Malin, Ericson, Ulrika, Wirfält, Elisabet, Key, Tim J, Travis, Ruth C, Gunter, Marc, Riboli, Elio, Vergnaud, Anne-Claire, and Romieu, Isabelle
Published: 2015
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24. Meat and fish consumption and the risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition

Author: Rohrmann, Sabine, Linseisen, Jakob, Overvad, Kim, Lund Würtz, Anne Mette, Roswall, Nina, Tjonneland, Anne, Boutron-Ruault, Marie-Christine, Racine, Antoine, Bastide, Nadia, Palli, Domenico, Agnoli, Claudia, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, Weikert, Steffen, Steffen, Annika, Kühn, Tilman, Li, Kuanrong, Khaw, Kay-Tee, Wareham, Nicholas J., Bradbury, Kathryn E., Peppa, Eleni, Trichopoulou, Antonia, Trichopoulos, Dimitrios, Bueno-de-Mesquita, H. B(as), Peeters, Petra H.M., Hjartåker, Anette, Skeie, Guri, Weiderpass, Elisabete, Jakszyn, Paula, Dorronsoro, Miren, Barricarte, Aurelio, de Pablos, Carmen Santiuste, Molina-Montes, Esther, de la Torre, Ramón Alonso, Ericson, Ulrika, Sonestedt, Emily, Johansson, Mattias, Ljungberg, Börje, Freisling, Heinz, Romieu, Isabelle, Cross, Amanda J., Vergnaud, Anne-Claire, Riboli, Elio, and Boeing, Heiner
Published: 2015
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25. Trends in the prevalence of obesity in employed adults in central-western France: A population-based study, 1995–2005

Author: Czernichow, Sébastien, Vergnaud, Anne-Claire, Maillard-Teyssier, Laurence, Péneau, Sandrine, Bertrais, Sandrine, Méjean, Caroline, Vol, Sylviane, Tichet, Jean, and Hercberg, Serge
Published: 2009
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26. Dairy consumption and 6-y changes in body weight and waist circumference in middle-aged French adults

Author: Vergnaud, Anne-Claire, Péneau, Sandrine, Chat-Yung, Stacie, Kesse, Emmanuelle, Czernichow, Sébastien, Galan, Pilar, Hercberg, Serge, and Bertrais, Sandrine
Published: 2008
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27. Agreement between web-based and paper versions of a socio-demographic questionnaire in the NutriNet-Santé study

Author: Vergnaud, Anne-Claire, Touvier, Mathilde, Méjean, Caroline, Kesse-Guyot, Emmanuelle, Pollet, Clothilde, Malon, Aurélie, Castetbon, Katia, and Hercberg, Serge
Published: 2011
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28. Relationship between iron status and dietary fruit and vegetables based on their vitamin C and fiber content

Author: Péneau, Sandrine, Dauchet, Luc, Vergnaud, Anne-Claire, Estaquio, Carla, Kesse-Guyot, Emmanuelle, Bertrais, Sandrine, Latino-Martel, Paule, Hercberg, Serge, and Galan, Pilar
Published: 2008
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29. Liver stiffness values in apparently healthy subjects: Influence of gender and metabolic syndrome

Author: Roulot, Dominique, Czernichow, Sébastien, Le Clésiau, Hervé, Costes, Jean-Luc, Vergnaud, Anne-Claire, and Beaugrand, Michel
Published: 2008
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30. Pulse pressure amplification, adiposity and metabolic syndrome in subjects under chronic antihypertensive therapy: The role of heart rate

Author: Vergnaud, Anne Claire, Protogerou, Athanase D., Li, Yan, Czernichow, Sébastien, Vesin, Claire, Blacher, Jacques, and Safar, Michel E.
Published: 2008
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31. Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition

Author: Leenders, Max, Leufkens, Anke M., Siersema, Peter D., van Duijnhoven, Fränzel J.B., Vrieling, Alina, Hulshof, Paul J.M., van Gils, Carla H., Overvad, Kim, Roswall, Nina, Kyr, Cecilie, Boutron-Ruault, Marie-Christine, Fagerhazzi, Guy, Cadeau, Claire, Kühn, Tilman, Johnson, Theron, Boeing, Heiner, Aleksandrova, Krasimira, Trichopoulou, Antonia, Klinaki, Eleni, Androulidaki, Anna, Palli, Domenico, Grioni, Sara, Sacerdote, Carlotta, Tumino, Rosario, Panico, Salvatore, Bakker, Marije F., Skeie, Guri, Weiderpass, Elisabete, Jakszyn, Paula, Barricarte, Aurelio, Huerta, José María, Molina-Montes, Esther, Argüelles, Marcial, Johansson, Ingegerd, Ljuslinder, Ingrid, Key, Timothy J., Bradbury, Kathryn E., Khaw, Kay-Tee, Wareham, Nicholas J., Ferrari, Pietro, Duarte-Salles, Talita, Jenab, Mazda, Gunter, Marc J., Vergnaud, Anne-Claire, Wark, Petra A., and Bueno-de-Mesquita, H. B(as)
Published: 2014
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32. Dietary patterns and blood pressure change over 5-y follow-up in the SU.VI.MAX cohort

Author: Dauchet, Luc, Kesse-Guyot, Emmanuelle, Czernichow, Sébastien, Bertrais, Sandrine, Estaquio, Carla, Péneau, Sandrine, Vergnaud, Anne-Claire, Chat-Yung, Stacie, Castetbon, Katia, Deschamps, Valérie, Brindel, Pauline, and Hercberg, Serge
Published: 2007
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33. Polymorphisms of Helicobacter pylori signaling pathway genes and gastric cancer risk in the European prospective investigation into cancer-eurgast cohort

Author: Companioni, Osmel, Bonet, Catalina, Muñoz, Xavier, Weiderpass, Elisabete, Panico, Salvatore, Tumino, Rosario, Palli, Domenico, Agnoli, Claudia, Vineis, Paolo, Boutron-Ruault, Marie-Christine, Racine, Antoine, Clavel-Chapelon, Françoise, Travis, Ruth C., Khaw, Kay-Tee, Riboli, Elio, Murphy, Neil, Vergnaud, Anne-Claire, Trichopoulou, Antonia, Benetou, Vassiliki, Trichopoulos, Dimitrios, Lund, Eiliv, Johansen, Dorthe, Lindkvist, Björn, Johansson, Mattias, Sund, Malin, Ardanaz, Eva, Sánchez-Cantalejo, Emilio, Huerta, Jose M., Dorronsoro, Miren, Quirós, José Ramón, Tjonneland, Anne, Mortensen, Lotte Maxild, Overvad, Kim, Chang-Claude, Jenny, Rizzato, Cosmeri, Boeing, Heiner, de Mesquita, Bas H. Bueno, Siersema, Peter, Peeters, Petra H.M., Numans, Mattijs E., Carneiro, Fatima, Licaj, Idlir, Freisling, Heinz, Sala, Núria, and González, Carlos A.
Published: 2014
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34. Meat and heme iron intake and esophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study

Author: Jakszyn, Paula, Luján-Barroso, Leila, Agudo, Antonio, Bueno-de-Mesquita, Bas H., Molina, Esther, Sánchez, M José, Fonseca-Nunes, Ana, Siersema, Peter D, Matiello, Amalia, Tumino, Rosario, Saieva, Calogero, Pala, Valeria, Vineis, Paolo, Boutron-Ruault, Marie-Christine, Racine, Antoine, Bastide, Nadie, Travis, Ruth C., Khaw, Kay-Tee, Riboli, Elio, Murphy, Neil, Vergnaud, Anne-Claire, Trichopoulou, Antonia, Valanou, Elissavet, Oikonomidou, Despina E, Weiderpass, Elisabete, Skeie, Guri, Johansen, Dorthe, Lindkvist, Björn, Johansson, Mattias, Duarte-Salles, Talita, Freisling, Heinz, Barricarte, Aurelio, M Huerta, Jose, Amiano, Pilar, Tjonneland, Anne, Overvad, Kim, Kuehn, Tilman, Grote, Verena, Boeing, Heiner, Peeters, Petra HM, and González, Carlos A
Published: 2013
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35. Reply to E Falk Libby et al

Author: Vergnaud, Anne-Claire, Romaguera, Dora, Peeters, Petra HM, van Gils, Carla H, Chan, Doris SM, Bergmann, Manuela M, and Norat, Teresa
Published: 2013
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36. Antioxidant supplementation does not affect fasting plasma glucose in the Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) study in France: association with dietary intake and plasma concentrations

Author: Czernichow, Sébastien, Couthouis, Aline, Bertrais, Sandrine, Vergnaud, Anne-Claire, Dauchet, Luc, Galan, Pilar, and Hercberg, Serge
Published: 2006
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37. Lower educational level is a predictor of incident type 2 diabetes in European countries: The EPIC-InterAct study

Author: Sacerdote, Carlotta, Ricceri, Fulvio, Rolandsson, Olov, Baldi, Ileana, Chirlaque, Maria-Dolores, Feskens, Edith, Bendinelli, Benedetta, Ardanaz, Eva, Arriola, Larraitz, Balkau, Beverley, Bergmann, Manuela, Beulens, Joline WJ, Boeing, Heiner, Clavel-Chapelon, Françoise, Crowe, Francesca, de Lauzon-Guillain, Blandine, Forouhi, Nita, Franks, Paul W, Gallo, Valentina, Gonzalez, Carlos, Halkjær, Jytte, Illner, Anne-Kathrin, Kaaks, Rudolf, Key, Timothy, Khaw, Kay-Tee, Navarro, Carmen, Nilsson, Peter M, Dal ton, Susanne Oksbjerg, Overvad, Kim, Pala, Valeria, Palli, Domenico, Panico, Salvatore, Polidoro, Silvia, Quirós, J Ramón, Romieu, Isabelle, Sánchez, María-José, Slimani, Nadia, Sluijs, Ivonne, Spijkerman, Annemieke, Teucher, Birgit, Tjønneland, Anne, Tumino, Rosario, van der A, Daphne, Vergnaud, Anne-Claire, Wennberg, Patrik, Sharp, Stephen, Langenberg, Claudia, Riboli, Elio, Vineis, Paolo, and Wareham, Nicholas
Published: 2012
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38. Consumption of meat and dairy and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition

Author: Rohrmann, Sabine, Linseisen, Jakob, Jakobsen, Marianne Uhre, Overvad, Kim, Raaschou-Nielsen, Ole, Tjonneland, Anne, Boutron-Ruault, Marie Christine, Kaaks, Rudolf, Becker, Nikolaus, Bergmann, Manuela, Boeing, Heiner, Khaw, Kay-Tee, Wareham, Nicholas J., Key, Timothy J., Travis, Ruth, Benetou, Vassiliki, Naska, Androniki, Trichopoulou, Antonia, Pala, Valeria, Tumino, Rosario, Masala, Giovanna, Mattiello, Amalia, Brustad, Magritt, Lund, Eiliv, Skeie, Guri, Bueno-de-Mesquita, Bas H., Peeters, Petra H.M., Vermeulen, Roel C.H., Jakszyn, Paula, Dorronsoro, Miren, Barricarte, Aurelio, Tormo, Maria-Jose, Molina, Esther, Argüelles, Marcial, Melin, Beatrice, Ericson, Ulrika, Manjer, Jonas, Rinaldi, Sabina, Slimani, Nadia, Boffetta, Paolo, Vergnaud, Anne-Claire, Khan, Aneire, Norat, Teresa, and Vineis, Paolo
Published: 2011
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39. Consommation d’huiles et matières grasses en France : relations avec le niveau d’étude et la région de résidence dans la cohorte SU.VI.MAX

Author: Czernichow, Sébastien, Vergnaud, Anne-Claire, Bruckert, Eric, Oppert, Jean-Michel, Bertrais, Sandrine, Paillard, François, Astorg, Pierre, Arnault, Nathalie, Galan, Pilar, and Hercberg, Serge
Published: 2005
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40. Effects of light to moderate alcohol consumption on thyroid volume and thyroid function

Author: Valeix, Pierre, Faure, Patrice, Bertrais, Sandrine, Vergnaud, Anne-Claire, Dauchet, Luc, and Hercberg, Serge
Published: 2008

41. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.

Author: Surendran, Praveen, Feofanova, Elena V, Lahrouchi, Najim, Ntalla, Ioanna, Karthikeyan, Savita, Cook, James, Chen, Lingyan, Mifsud, Borbala, Yao, Chen, Kraja, Aldi T, Cartwright, James H, Hellwege, Jacklyn N, Giri, Ayush, Tragante, Vinicius, Thorleifsson, Gudmar, Liu, Dajiang J, Prins, Bram P, Stewart, Isobel D, Cabrera, Claudia P, Eales, James M, Akbarov, Artur, Auer, Paul L, Bielak, Lawrence F, Bis, Joshua C, Braithwaite, Vickie S, Brody, Jennifer A, Daw, E Warwick, Warren, Helen R, Drenos, Fotios, Nielsen, Sune Fallgaard, Faul, Jessica D, Fauman, Eric B, Fava, Cristiano, Ferreira, Teresa, Foley, Christopher N, Franceschini, Nora, Gao, He, Giannakopoulou, Olga, Giulianini, Franco, Gudbjartsson, Daniel F, Guo, Xiuqing, Harris, Sarah E, Havulinna, Aki S, Helgadottir, Anna, Huffman, Jennifer E, Hwang, Shih-Jen, Kanoni, Stavroula, Kontto, Jukka, Larson, Martin G, Li-Gao, Ruifang, Lindström, Jaana, Lotta, Luca A, Lu, Yingchang, Luan, Jian'an, Mahajan, Anubha, Malerba, Giovanni, Masca, Nicholas G D, Mei, Hao, Menni, Cristina, Mook-Kanamori, Dennis O, Mosen-Ansorena, David, Müller-Nurasyid, Martina, Paré, Guillaume, Paul, Dirk S, Perola, Markus, Poveda, Alaitz, Rauramaa, Rainer, Richard, Melissa, Richardson, Tom G, Sepúlveda, Nuno, Sim, Xueling, Smith, Albert V, Smith, Jennifer A, Staley, James R, Stanáková, Alena, Sulem, Patrick, Thériault, Sébastien, Thorsteinsdottir, Unnur, Trompet, Stella, Varga, Tibor V, Velez Edwards, Digna R, Veronesi, Giovanni, Weiss, Stefan, Willems, Sara M, Yao, Jie, Young, Robin, Yu, Bing, Zhang, Weihua, Zhao, Jing-Hua, Zhao, Wei, Evangelou, Evangelos, Aeschbacher, Stefanie, Asllanaj, Eralda, Blankenberg, Stefan, Bonnycastle, Lori L, Bork-Jensen, Jette, Brandslund, Ivan, Braund, Peter S, Burgess, Stephen, Cho, Kelly, Christensen, Cramer, Connell, John, Mutsert, Renée de, Dominiczak, Anna F, Dörr, Marcus, Eiriksdottir, Gudny, Farmaki, Aliki-Eleni, Gaziano, J Michael, Grarup, Niels, Grove, Megan L, Hallmans, Göran, Hansen, Torben, Have, Christian T, Heiss, Gerardo, Jørgensen, Marit E, Jousilahti, Pekka, Kajantie, Eero, Kamat, Mihir, Käräjämäki, AnneMari, Karpe, Fredrik, Koistinen, Heikki A, Kovesdy, Csaba P, Kuulasmaa, Kari, Laatikainen, Tiina, Lannfelt, Lars, Lee, I-Te, Lee, Wen-Jane, Linneberg, Allan, Martin, Lisa W, Moitry, Marie, Nadkarni, Girish, Neville, Matt J, Palmer, Colin N A, Papanicolaou, George J, Pedersen, Oluf, Peters, James, Poulter, Neil, Rasheed, Asif, Rasmussen, Katrine L, Rayner, N William, Mägi, Reedik, Renström, Frida, Rettig, Rainer, Rossouw, Jacques, Schreiner, Pamela J, Sever, Peter S, Sigurdsson, Emil L, Skaaby, Tea, Sun, Yan V, Sundström, Johan, Thorgeirsson, Gudmundur, Esko, Tõnu, Trabetti, Elisabetta, Tsao, Philip S, Tuomi, Tiinamaija, Turner, Stephen T, Tzoulaki, Ioanna, Vaartjes, Ilonca, Vergnaud, Anne-Claire, Willer, Cristen J, Wilson, Peter W F, Witte, Daniel R, Yonova-Doing, Ekaterina, Zhang, He, Aliya, Naheed, Almgren, Peter, Amouyel, Philippe, Asselbergs, Folkert W, Barnes, Michael R, Blakemore, Alexandra I, Boehnke, Michael, Bots, Michiel L, Bottinger, Erwin P, Buring, Julie E, Chambers, John C, Chen, Yii-Der Ida, Chowdhury, Rajiv, Conen, David, Correa, Adolfo, Davey Smith, George, Boer, Rudolf A de, Deary, Ian J, Dedoussis, George, Deloukas, Panos, Di Angelantonio, Emanuele, Elliott, Paul, Felix, Stephan B, Ferrières, Jean, Ford, Ian, Fornage, Myriam, Franks, Paul W, Franks, Stephen, Frossard, Philippe, Gambaro, Giovanni, Gaunt, Tom R, Groop, Leif, Gudnason, Vilmundur, Harris, Tamara B, Hayward, Caroline, Hennig, Branwen J, Herzig, Karl-Heinz, Ingelsson, Erik, Tuomilehto, Jaakko, Järvelin, Marjo-Riitta, Jukema, J Wouter, Kardia, Sharon L R, Kee, Frank, Kooner, Jaspal S, Kooperberg, Charles, Launer, Lenore J, Lind, Lars, Loos, Ruth J F, Majumder, Abdulla Al Shafi, Laakso, Markku, McCarthy, Mark I, Melander, Olle, Mohlke, Karen L, Murray, Alison D, Nordestgaard, Børge Grønne, Orho-Melander, Marju, Packard, Chris J, Padmanabhan, Sandosh, Palmas, Walter, Polasek, Ozren, Porteous, David J, Prentice, Andrew M, Province, Michael A, Relton, Caroline L, Rice, Kenneth, Ridker, Paul M, Rolandsson, Olov, Rosendaal, Frits R, Rotter, Jerome I, Rudan, Igor, Salomaa, Veikko, Samani, Nilesh J, Sattar, Naveed, Sheu, Wayne H-H, Smith, Blair H, Soranzo, Nicole, Spector, Timothy D, Starr, John M, Sebert, Sylvain, Taylor, Kent D, Lakka, Timo A, Timpson, Nicholas J, Tobin, Martin D, van der Harst, Pim, van der Meer, Peter, Ramachandran, Vasan S, Verweij, Niek, Virtamo, Jarmo, Völker, Uwe, Weir, David R, Zeggini, Eleftheria, Charchar, Fadi J, Wareham, Nicholas J, Langenberg, Claudia, Tomaszewski, Maciej, Butterworth, Adam S, Caulfield, Mark J, Danesh, John, Edwards, Todd L, Holm, Hilma, Hung, Adriana M, Lindgren, Cecilia M, Liu, Chunyu, Manning, Alisa K, Morris, Andrew P, Morrison, Alanna C, O'Donnell, Christopher J, Psaty, Bruce M, Saleheen, Danish, Stefansson, Kari, Boerwinkle, Eric, Chasman, Daniel I, Levy, Daniel, Newton-Cheh, Christopher, Munroe, Patricia B, Howson, Joanna M M, Surendran, Praveen, Feofanova, Elena V, Lahrouchi, Najim, Ntalla, Ioanna, Karthikeyan, Savita, Cook, James, Chen, Lingyan, Mifsud, Borbala, Yao, Chen, Kraja, Aldi T, Cartwright, James H, Hellwege, Jacklyn N, Giri, Ayush, Tragante, Vinicius, Thorleifsson, Gudmar, Liu, Dajiang J, Prins, Bram P, Stewart, Isobel D, Cabrera, Claudia P, Eales, James M, Akbarov, Artur, Auer, Paul L, Bielak, Lawrence F, Bis, Joshua C, Braithwaite, Vickie S, Brody, Jennifer A, Daw, E Warwick, Warren, Helen R, Drenos, Fotios, Nielsen, Sune Fallgaard, Faul, Jessica D, Fauman, Eric B, Fava, Cristiano, Ferreira, Teresa, Foley, Christopher N, Franceschini, Nora, Gao, He, Giannakopoulou, Olga, Giulianini, Franco, Gudbjartsson, Daniel F, Guo, Xiuqing, Harris, Sarah E, Havulinna, Aki S, Helgadottir, Anna, Huffman, Jennifer E, Hwang, Shih-Jen, Kanoni, Stavroula, Kontto, Jukka, Larson, Martin G, Li-Gao, Ruifang, Lindström, Jaana, Lotta, Luca A, Lu, Yingchang, Luan, Jian'an, Mahajan, Anubha, Malerba, Giovanni, Masca, Nicholas G D, Mei, Hao, Menni, Cristina, Mook-Kanamori, Dennis O, Mosen-Ansorena, David, Müller-Nurasyid, Martina, Paré, Guillaume, Paul, Dirk S, Perola, Markus, Poveda, Alaitz, Rauramaa, Rainer, Richard, Melissa, Richardson, Tom G, Sepúlveda, Nuno, Sim, Xueling, Smith, Albert V, Smith, Jennifer A, Staley, James R, Stanáková, Alena, Sulem, Patrick, Thériault, Sébastien, Thorsteinsdottir, Unnur, Trompet, Stella, Varga, Tibor V, Velez Edwards, Digna R, Veronesi, Giovanni, Weiss, Stefan, Willems, Sara M, Yao, Jie, Young, Robin, Yu, Bing, Zhang, Weihua, Zhao, Jing-Hua, Zhao, Wei, Evangelou, Evangelos, Aeschbacher, Stefanie, Asllanaj, Eralda, Blankenberg, Stefan, Bonnycastle, Lori L, Bork-Jensen, Jette, Brandslund, Ivan, Braund, Peter S, Burgess, Stephen, Cho, Kelly, Christensen, Cramer, Connell, John, Mutsert, Renée de, Dominiczak, Anna F, Dörr, Marcus, Eiriksdottir, Gudny, Farmaki, Aliki-Eleni, Gaziano, J Michael, Grarup, Niels, Grove, Megan L, Hallmans, Göran, Hansen, Torben, Have, Christian T, Heiss, Gerardo, Jørgensen, Marit E, Jousilahti, Pekka, Kajantie, Eero, Kamat, Mihir, Käräjämäki, AnneMari, Karpe, Fredrik, Koistinen, Heikki A, Kovesdy, Csaba P, Kuulasmaa, Kari, Laatikainen, Tiina, Lannfelt, Lars, Lee, I-Te, Lee, Wen-Jane, Linneberg, Allan, Martin, Lisa W, Moitry, Marie, Nadkarni, Girish, Neville, Matt J, Palmer, Colin N A, Papanicolaou, George J, Pedersen, Oluf, Peters, James, Poulter, Neil, Rasheed, Asif, Rasmussen, Katrine L, Rayner, N William, Mägi, Reedik, Renström, Frida, Rettig, Rainer, Rossouw, Jacques, Schreiner, Pamela J, Sever, Peter S, Sigurdsson, Emil L, Skaaby, Tea, Sun, Yan V, Sundström, Johan, Thorgeirsson, Gudmundur, Esko, Tõnu, Trabetti, Elisabetta, Tsao, Philip S, Tuomi, Tiinamaija, Turner, Stephen T, Tzoulaki, Ioanna, Vaartjes, Ilonca, Vergnaud, Anne-Claire, Willer, Cristen J, Wilson, Peter W F, Witte, Daniel R, Yonova-Doing, Ekaterina, Zhang, He, Aliya, Naheed, Almgren, Peter, Amouyel, Philippe, Asselbergs, Folkert W, Barnes, Michael R, Blakemore, Alexandra I, Boehnke, Michael, Bots, Michiel L, Bottinger, Erwin P, Buring, Julie E, Chambers, John C, Chen, Yii-Der Ida, Chowdhury, Rajiv, Conen, David, Correa, Adolfo, Davey Smith, George, Boer, Rudolf A de, Deary, Ian J, Dedoussis, George, Deloukas, Panos, Di Angelantonio, Emanuele, Elliott, Paul, Felix, Stephan B, Ferrières, Jean, Ford, Ian, Fornage, Myriam, Franks, Paul W, Franks, Stephen, Frossard, Philippe, Gambaro, Giovanni, Gaunt, Tom R, Groop, Leif, Gudnason, Vilmundur, Harris, Tamara B, Hayward, Caroline, Hennig, Branwen J, Herzig, Karl-Heinz, Ingelsson, Erik, Tuomilehto, Jaakko, Järvelin, Marjo-Riitta, Jukema, J Wouter, Kardia, Sharon L R, Kee, Frank, Kooner, Jaspal S, Kooperberg, Charles, Launer, Lenore J, Lind, Lars, Loos, Ruth J F, Majumder, Abdulla Al Shafi, Laakso, Markku, McCarthy, Mark I, Melander, Olle, Mohlke, Karen L, Murray, Alison D, Nordestgaard, Børge Grønne, Orho-Melander, Marju, Packard, Chris J, Padmanabhan, Sandosh, Palmas, Walter, Polasek, Ozren, Porteous, David J, Prentice, Andrew M, Province, Michael A, Relton, Caroline L, Rice, Kenneth, Ridker, Paul M, Rolandsson, Olov, Rosendaal, Frits R, Rotter, Jerome I, Rudan, Igor, Salomaa, Veikko, Samani, Nilesh J, Sattar, Naveed, Sheu, Wayne H-H, Smith, Blair H, Soranzo, Nicole, Spector, Timothy D, Starr, John M, Sebert, Sylvain, Taylor, Kent D, Lakka, Timo A, Timpson, Nicholas J, Tobin, Martin D, van der Harst, Pim, van der Meer, Peter, Ramachandran, Vasan S, Verweij, Niek, Virtamo, Jarmo, Völker, Uwe, Weir, David R, Zeggini, Eleftheria, Charchar, Fadi J, Wareham, Nicholas J, Langenberg, Claudia, Tomaszewski, Maciej, Butterworth, Adam S, Caulfield, Mark J, Danesh, John, Edwards, Todd L, Holm, Hilma, Hung, Adriana M, Lindgren, Cecilia M, Liu, Chunyu, Manning, Alisa K, Morris, Andrew P, Morrison, Alanna C, O'Donnell, Christopher J, Psaty, Bruce M, Saleheen, Danish, Stefansson, Kari, Boerwinkle, Eric, Chasman, Daniel I, Levy, Daniel, Newton-Cheh, Christopher, Munroe, Patricia B, and Howson, Joanna M M
Abstract: Genetic studies of blood pressure (BP) to date have mainly analyzed common variants (minor allele frequency > 0.05). In a meta-analysis of up to ~1.3 million participants, we discovered 106 new BP-associated genomic regions and 87 rare (minor allele frequency ≤ 0.01) variant BP associations (P < 5 × 10-8), of which 32 were in new BP-associated loci and 55 were independent BP-associated single-nucleotide variants within known BP-associated regions. Average effects of rare variants (44% coding) were ~8 times larger than common variant effects and indicate potential candidate causal genes at new and known loci (for example, GATA5 and PLCB3). BP-associated variants (including rare and common) were enriched in regions of active chromatin in fetal tissues, potentially linking fetal development with BP regulation in later life. Multivariable Mendelian randomization suggested possible inverse effects of elevated systolic and diastolic BP on large artery stroke. Our study demonstrates the utility of rare-variant analyses for identifying candidate genes and the results highlight potential therapeutic targets.
Published: 2020
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42. Determinants of non- response to a second assessment of lifestyle factors and body weight in the EPIC-PANACEA study

Author: May Anne M, Adema Lotte E, Romaguera Dora, Vergnaud Anne-Claire, Agudo Antonio, Ekelund Ulf, Steffen Annika, Orfanos Philippos, Slimani Nadia, Rinaldi Sabina, Mouw Traci, Rohrmann Sabine, Hermann Silke, Boeing Heiner, Bergmann Manuela M, Jakobsen Marianne, Overvad Kim, Wareham Nicholas J, Gonzalez Carlos, Tjonneland Anne, Halkjaer Jytte, Key Timothy J, Spencer Elizabeth A, Hellstrom Veronica, Manjer Jonas, Hedblad Bo, Lund Eiliv, Braaten Tonje, Clavel-Chapelon Françoise, Boutron-Ruault Marie-Christine, Rodríguez Laudina, Sánchez Maria J, Dorronsoro Miren, Barricarte Aurelio, Huerta Jose, Naska Androniki, Trichopoulou Antonia, Palli Domenico, Pala Valeria, Norat Teresa, Mattiello Amalia, Tumino Rosario, van der A Daphne, Bueno-de-Mesquita H, Riboli Elio, and Peeters Petra HM
Subjects: Non-response, Non-participation, Lost-to-follow-up, Medicine (General), R5-920
Abstract: Abstract Background This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-center EPIC-PANACEA study. Methods Over 500.000 participants from several centers in ten European countries recruited between 1992 and 2000 were contacted 2–11 years later to update data on lifestyle and body weight. Length of follow-up as well as the method of approaching differed between the collaborating study centers. Non-responders were compared with responders using multivariate logistic regression analyses. Results Overall response for the second assessment was high (81.6%). Compared to postal surveys, centers where the participants completed the questionnaire by phone attained a higher response. Response was also high in centers with a short follow-up period. Non-response was higher in participants who were male (odds ratio 1.09 (confidence interval 1.07; 1.11), aged under 40 years (1.96 (1.90; 2.02), living alone (1.40 (1.37; 1.43), less educated (1.35 (1.12; 1.19), of poorer health (1.33 (1.27; 1.39), reporting an unhealthy lifestyle and who had either a low (25, 1.08 (1.06; 1.10); especially ≥30 kg/m2, 1.26 (1.23; 1.29)). Conclusions Cohort studies may enhance cohort maintenance by paying particular attention to the subgroups that are most unlikely to respond and by an active recruitment strategy using telephone interviews.
Published: 2012
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43. Changes in leisure-time physical activity and sedentary behaviour at retirement: a prospective study in middle-aged French subjects

Author: Hercberg Serge, Vergnaud Anne-Claire, Charreire Hélène, Bertrais Sandrine, Touvier Mathilde, and Oppert Jean-Michel
Subjects: Nutritional diseases. Deficiency diseases, RC620-627, Public aspects of medicine, RA1-1270
Abstract: Abstract Background Longitudinal studies on physical activity patterns around retirement age are scarce and provide divergent findings. Little is known about changes in sedentary behaviour in this context. Our aim was to investigate relationships between retirement and 3-year changes in leisure-time physical activity (LTPA) patterns and sedentary behaviour in middle-aged French adults. Methods Past-year LTPA and sedentary behaviour (watching television) were assessed in 1998 and 2001 using the Modifiable Activity Questionnaire on participants in the SU.VI.MAX (Supplementation with Antioxidants and Minerals) study. A total of 698 men and 691 women aged 45-64 were included in this analysis. Comparisons were made between subjects who had retired between 1998 and 2001 and those who continued to work, using the Chi-square test, Student t-test, Wilcoxon rank test or covariance analysis where appropriate. Results 20.1% of men and 15.6% of women retired during follow-up. The baseline LTPA level was similar between subjects who retired during follow-up and those who continued to work. Mean LTPA increased by about 2 h/week in men and women who had retired, whereas no change was observed in employed persons. The positive change in LTPA following retirement was mainly related to an increase in activities of moderate intensity, such as walking. Retirement did not modify the ranking of the most frequently performed LTPAs, but the number of participants and the duration increased through retirement. In men, the increase in time spent watching TV was more than twice as high in retirees as in workers (+40.5 vs. +15.0 min/day, P < 0.0001). The same tendency was observed among women, but was borderline non-significant (+33.5 vs. +19.9 min/day, P = 0.05). In women, retirees who increased their walking duration by 2 h/week or more also decreased time spent watching TV by 11.5 min/day. Conclusions Retirement was associated with both an increase in LTPAs and in time spent watching TV, suggesting that retirement is an important period not only for promoting physical activity, but also for limiting sedentary behaviour.
Published: 2010
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44. Dietary assessment of British police force employees:a description of diet record coding procedures and cross-sectional evaluation of dietary energy intake reporting (The Airwave Health Monitoring Study)

Author: Gibson, Rachel, Eriksen, Rebeca, Lamb, Kathryn, McMeel, Yvonne, Vergnaud, Anne-Claire, Spear, Jeanette, Aresu, Maria, Chan, Queenie, Elliott, Paul, Frost, Gary, Home Office, National Institute for Health Research, Imperial College Healthcare NHS Trust- BRC Funding, and Medical Research Council (MRC)
Subjects: NATIONAL-HEALTH, Adult, Male, NUTRITION & DIETETICS, NUTRITION EXAMINATION SURVEY, EATING FREQUENCY, VALIDATION, Body Mass Index, Medicine, General & Internal, FOOD, General & Internal Medicine, Evaluation Studies, Journal Article, EPIDEMIOLOGY, Humans, CORONARY-HEART-DISEASE, Obesity, Prospective Studies, Exercise, RISK, OCCUPATIONAL & INDUSTRIAL MEDICINE, Science & Technology, Research, Incidence, Research Support, Non-U.S. Gov't, WOMEN, ADULTS, Diet Records, Police, United Kingdom, PHYSICAL-ACTIVITY, Cross-Sectional Studies, Nutrition Assessment, Female, Self Report, Energy Intake, Life Sciences & Biomedicine
Abstract: Objectives: Dietary intake is a key aspect of occupational health. To capture the characteristics of dietary behaviour that is affected by occupational environment that may impact on disease risk, collection of prospective multi - day dietary records are required. The aims of this paper are to: i) the collection of multi da y dietary data in the Airwaves health monitoring study, ii) describe the dietary coding procedures applied and ii i ) investigate the plausibility of dietary reporting in this occupational cohort. Design: A dietary coding protocol for this large - scale study was developed to minimise coding error rate. Participants ( n 4,412) who completed 7 - day food records were included for cross - sectional analyses. Energy intake misreporting was estimated using the Goldberg method. Multivariate logistic regression models we re applied to determine participant characteristics associated with energy intake misreporting. Setting: British police force employees enrolled (2007 to 2012) into the Airwave Health Monitoring Study. Results: The mean code error rate per food diary was 3.7% (SD 3.2%). The strongest predictors of energy intake under - reporting were body mass index (BMI) and physical activity. Compared to participants with BMI 30kg/m2 had increased odds of being classified as under - reporting energ y intake (men OR 5.20 95%CI 3.92, 6.89; women OR 2.66 95%CI 1.85, 3.83). Men and women in the highest physical activity category compared to the lowest were also more likely to be classified as under - reporting (men OR 3.33 95%CI 2.46, 4.50; women OR 4.34 9 5%CI 2.91, 6.55). Conclusions: A reproducible dietary record coding procedure h as been developed to minimise coding error in complex 7 - day diet diaries. The prevalence of energy intake under - reporting is comparable to existing national UK cohort s and, in agreement with previous studies classification of under - reporting was biased towards specific sub groups of participants.
Published: 2017
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45. Personal radio use and cancer risks among 48,518 British police officers and staff from the Airwave Health Monitoring Study

Author: Gao, He, primary, Aresu, Maria, additional, Vergnaud, Anne-Claire, additional, McRobie, Dennis, additional, Spear, Jeanette, additional, Heard, Andy, additional, Kongsgård, Håvard Wahl, additional, Singh, Deepa, additional, Muller, David C., additional, and Elliott, Paul, additional
Published: 2018
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46. Genetic analysis of over one million people identifies 535 new loci associated with blood pressure traits

Author: Evangelou, Evangelos, Warren, Helen R., Mosen-Ansorena, David, Mifsud, Borbala, Pazoki, Raha, Gao, He, Ntritsos, Georgios, Dimou, Niki, Cabrera, Claudia, Karaman, Ibrahim, Ng, Fu Liang, Evangelou, Marina, Witkowska, Katarzyna, Tzanis, Evan, Hellwege, Jacklyn, Giri, Ayush, Edwards, Digna R. Velez, Sun, Yan V., Cho, Kelly, Gaziano, J. Michael, Wilson, Peter W.F., Tsao, Philip S., Kovesdy, Csaba P., Esko, Tonu, Magi, Reedik, Milani, Lili, Almgren, Peter, Boutin, Thibaud, Debette, Stephanie, Ding, Jun, Giulianini, Franco, Holliday, Elizabeth G., Jackson, Anne U., Li-Gao, Ruifang, Lin, Wei-Yu, Luan, Jian'an, Mangino, Massimo, Oldmeadow, Christopher, Prins, Bram Peter, Qian, Yong, Sargurupremraj, Muralidharan, Shah, Nabi, Surendran, Praveen, Theriault, Sebastien, Verweij, Niek, Willems, Sara M., Zhao, Jing-Hua, Amouyel, Phillippe, Connell, John, de Mutsert, Renee, Doney, Alex S.F., Farrall, Martin, Menni, Cristina, Morris, Andrew D., Noordam, Raymond, Pare, Guillaume, Poulter, Neil R., Shields, Denis C., Stanton, Alice, Thom, Simon, Abecasis, Gonçalo, Amin, Najaf, Arking, Dan E., Ayers, Kristin L., Barbieri, Caterina M., Batini, Chiara, Bis, Joshua C., Blake, Tineka, Bochud, Murielle, Boehnke, Michael, Boerwinkle, Eric, Boomsma, Dorret I., Bottinger, Erwin P., Braund, Peter S., Brumat, Marco, Campbell, Archie, Campbell, Harry, Chakravarti, Aavinda, Chambers, John C., Chauhan, Ganesh, Ciullo, Marina, Cocca, Massimiliano, Collins, Francis, Cordell, Heather J., Davies, Gail, de Borst, Martin H., de Geus, Eco J., Deary, Ian J., Deelen, Joris, Del Greco, M. Fabiola, Demirkale, Cumhur Yusuf, Dörr, Marcus, Ehret, Georg B., Elosua, Roberto, Enroth, Stefan, Erzurumluoglu, A. Mesut, Ferreira, Teresa, Franberg, Mattias, Franco, Oscar H., Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Gieger, Christian, Girotto, Giorgia, Goel, Anuj, Gow, Alan, Gudnason, Vilmundur, Guo, Xiuqing, Gyllensten, Ulf, Hamsten, Anders, Harris, Tamara B., Harris, Sarah E., Hartman, Catharina A., Havulinna, Aki S., Hicks, Andrew A., Hofer, Edith, Hofman, Albert, Jottenga, Jouke-Jan, Huffman, Jennifer, Hwang, Shih-Jen, Ingelsson, Erik, James, Alan, Jansen, Rick, Jarvelin, Marjo-Riitta, Joehanes, Roby, Johansson, Asa, Johnson, Adnrew D., Joshi, Peter K., Jousilahti, Pekka, Jukema, J. Wouter, Jula, Antti, Kähönen, Mika, Kathiresan, Sekar, Keavney, Bernard D., Khaw, Kay-Tee, Knekt, Paul, Knight, Joanne, Kolcic, Ivana, Kooner, Jaspal S., Koskinen, Seppo, Kristiansson, Kati, Kutalik, Zoltan, Laan, Maris, Larson, Marty, Launer, Lenore J., Lehne, Benjamin, Lehtimäki, Terho, Liewald, David C.M., Lin, Li, Lind, Lars, Lindgren, Cecilia M., Liu, YongMei, Loos, Ruth J.F., Lopez, Lorna, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mahajan, Anubha, Mamasoula, Chrysovalanto, Marrugat, Jaume, Marten, Jonathan, Milaneschi, Yuri, Morgan, Anna, Morris, Andrew, Morrison, Alanna C., Munson, Peter J., Nalls, Mike A., Nandakumar, Priyanka, Nelson, Christopher P., Niiranen, Teemu, Nolte, Ilja M., Nutile, Teresa, Oldehinkel, Albertine J., Oostra, Ben A., O'Reilly, Paul F., Org, Elin, Padmanabhan, Sandosh, Palmas, Walter, Palotie, Aarno, Pattie, Alison, Polasek, Ozren, Pramstaller, Peter P., Nguyen, Quang Tri, Raitakari, Olli T., Ren, Meixia, Rettig, Rainer, Rice, Kenneth, Ridker, Paul M., Ried, Janina S., Riese, Harriëtte, Ripatti, Samuli, Robino, Antonietta, Rose, Lynda M., Rotter, Jerome I., Rudan, Igor, Ruggiero, Daniela, Saba, Yasaman, Sala, Cinzia F., Salomaa, Veikko, Samani, Nilesh J., Sarin, Antti-Pekka, Schmidt, Reinhold, Schmidt, Helena, Shrine, Nick, Siscovick, David, Smith, Albert V., Snieder, Harold, Sõber, Siim, Sorice, Rossella, Starr, John M., Stott, David, Strachan, David P., Strawbridge, Rona J., Sundström, Johan, Swertz, Morris A., Taylor, Kent D., Teumer, Alexander, Tobin, Martin D., Tomaszewski, Maciej, Toniolo, Daniela, Traglia, Michela, Trompet, Stella, Tuomilehto, Jaako, Tzourio, Christophe, Uitterlinden, Andre G., Vaez, Ahmad, van der Most, Peter J., van Duijn, Cornelia M., Vergnaud, Anne-Claire, verwoert, Germaine C., Vitart, Veronique, Völke, Uwe, Vollenweider, Peter, Vuckovic, Dragana, Watkins, Hugh, Wild, Sarah H., Willemsen, Gonneke, Wilson, James F., Wright, Alan F., Yao, Jie, Zemunik, Tatijana, Zhang, Weihua, Attia, John R., Butterworth, Adam S., Chasman, Daniel I., Conen, David, Cucca, Francesco, Danesh, John, Hayward, Caroline, Howson, Joanna M.M., Laakso, Markku, Lakatta, Edward G., Langenberg, Claudia, Melander, Olle, Mook-Kanamor, Dennis O., Palmer, Colin, Risch, Lorenz, Scott, Robert, Scott, Rodney, Sever, Peter, Spector, Tim D., van der Harst, Pim, Wareham, Nicholas J., Zeggini, Eleftheria, Levy, Daniel, Munroe, Patricia B., Newton-Cheh, Christopher, Brown, Morris J., Metspalu, Andres, Hung, Adriana M., O'Donnell, Christopher, Edwards, Todd L., Psaty, Bruce M., Tzoulaki, Ioanna, Barnes, Michael R., Wain, Louise V., Elliott, Paul, Caulfield, Mark J., Evangelou, Evangelos, Warren, Helen R., Mosen-Ansorena, David, Mifsud, Borbala, Pazoki, Raha, Gao, He, Ntritsos, Georgios, Dimou, Niki, Cabrera, Claudia, Karaman, Ibrahim, Ng, Fu Liang, Evangelou, Marina, Witkowska, Katarzyna, Tzanis, Evan, Hellwege, Jacklyn, Giri, Ayush, Edwards, Digna R. Velez, Sun, Yan V., Cho, Kelly, Gaziano, J. Michael, Wilson, Peter W.F., Tsao, Philip S., Kovesdy, Csaba P., Esko, Tonu, Magi, Reedik, Milani, Lili, Almgren, Peter, Boutin, Thibaud, Debette, Stephanie, Ding, Jun, Giulianini, Franco, Holliday, Elizabeth G., Jackson, Anne U., Li-Gao, Ruifang, Lin, Wei-Yu, Luan, Jian'an, Mangino, Massimo, Oldmeadow, Christopher, Prins, Bram Peter, Qian, Yong, Sargurupremraj, Muralidharan, Shah, Nabi, Surendran, Praveen, Theriault, Sebastien, Verweij, Niek, Willems, Sara M., Zhao, Jing-Hua, Amouyel, Phillippe, Connell, John, de Mutsert, Renee, Doney, Alex S.F., Farrall, Martin, Menni, Cristina, Morris, Andrew D., Noordam, Raymond, Pare, Guillaume, Poulter, Neil R., Shields, Denis C., Stanton, Alice, Thom, Simon, Abecasis, Gonçalo, Amin, Najaf, Arking, Dan E., Ayers, Kristin L., Barbieri, Caterina M., Batini, Chiara, Bis, Joshua C., Blake, Tineka, Bochud, Murielle, Boehnke, Michael, Boerwinkle, Eric, Boomsma, Dorret I., Bottinger, Erwin P., Braund, Peter S., Brumat, Marco, Campbell, Archie, Campbell, Harry, Chakravarti, Aavinda, Chambers, John C., Chauhan, Ganesh, Ciullo, Marina, Cocca, Massimiliano, Collins, Francis, Cordell, Heather J., Davies, Gail, de Borst, Martin H., de Geus, Eco J., Deary, Ian J., Deelen, Joris, Del Greco, M. Fabiola, Demirkale, Cumhur Yusuf, Dörr, Marcus, Ehret, Georg B., Elosua, Roberto, Enroth, Stefan, Erzurumluoglu, A. Mesut, Ferreira, Teresa, Franberg, Mattias, Franco, Oscar H., Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Gieger, Christian, Girotto, Giorgia, Goel, Anuj, Gow, Alan, Gudnason, Vilmundur, Guo, Xiuqing, Gyllensten, Ulf, Hamsten, Anders, Harris, Tamara B., Harris, Sarah E., Hartman, Catharina A., Havulinna, Aki S., Hicks, Andrew A., Hofer, Edith, Hofman, Albert, Jottenga, Jouke-Jan, Huffman, Jennifer, Hwang, Shih-Jen, Ingelsson, Erik, James, Alan, Jansen, Rick, Jarvelin, Marjo-Riitta, Joehanes, Roby, Johansson, Asa, Johnson, Adnrew D., Joshi, Peter K., Jousilahti, Pekka, Jukema, J. Wouter, Jula, Antti, Kähönen, Mika, Kathiresan, Sekar, Keavney, Bernard D., Khaw, Kay-Tee, Knekt, Paul, Knight, Joanne, Kolcic, Ivana, Kooner, Jaspal S., Koskinen, Seppo, Kristiansson, Kati, Kutalik, Zoltan, Laan, Maris, Larson, Marty, Launer, Lenore J., Lehne, Benjamin, Lehtimäki, Terho, Liewald, David C.M., Lin, Li, Lind, Lars, Lindgren, Cecilia M., Liu, YongMei, Loos, Ruth J.F., Lopez, Lorna, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mahajan, Anubha, Mamasoula, Chrysovalanto, Marrugat, Jaume, Marten, Jonathan, Milaneschi, Yuri, Morgan, Anna, Morris, Andrew, Morrison, Alanna C., Munson, Peter J., Nalls, Mike A., Nandakumar, Priyanka, Nelson, Christopher P., Niiranen, Teemu, Nolte, Ilja M., Nutile, Teresa, Oldehinkel, Albertine J., Oostra, Ben A., O'Reilly, Paul F., Org, Elin, Padmanabhan, Sandosh, Palmas, Walter, Palotie, Aarno, Pattie, Alison, Polasek, Ozren, Pramstaller, Peter P., Nguyen, Quang Tri, Raitakari, Olli T., Ren, Meixia, Rettig, Rainer, Rice, Kenneth, Ridker, Paul M., Ried, Janina S., Riese, Harriëtte, Ripatti, Samuli, Robino, Antonietta, Rose, Lynda M., Rotter, Jerome I., Rudan, Igor, Ruggiero, Daniela, Saba, Yasaman, Sala, Cinzia F., Salomaa, Veikko, Samani, Nilesh J., Sarin, Antti-Pekka, Schmidt, Reinhold, Schmidt, Helena, Shrine, Nick, Siscovick, David, Smith, Albert V., Snieder, Harold, Sõber, Siim, Sorice, Rossella, Starr, John M., Stott, David, Strachan, David P., Strawbridge, Rona J., Sundström, Johan, Swertz, Morris A., Taylor, Kent D., Teumer, Alexander, Tobin, Martin D., Tomaszewski, Maciej, Toniolo, Daniela, Traglia, Michela, Trompet, Stella, Tuomilehto, Jaako, Tzourio, Christophe, Uitterlinden, Andre G., Vaez, Ahmad, van der Most, Peter J., van Duijn, Cornelia M., Vergnaud, Anne-Claire, verwoert, Germaine C., Vitart, Veronique, Völke, Uwe, Vollenweider, Peter, Vuckovic, Dragana, Watkins, Hugh, Wild, Sarah H., Willemsen, Gonneke, Wilson, James F., Wright, Alan F., Yao, Jie, Zemunik, Tatijana, Zhang, Weihua, Attia, John R., Butterworth, Adam S., Chasman, Daniel I., Conen, David, Cucca, Francesco, Danesh, John, Hayward, Caroline, Howson, Joanna M.M., Laakso, Markku, Lakatta, Edward G., Langenberg, Claudia, Melander, Olle, Mook-Kanamor, Dennis O., Palmer, Colin, Risch, Lorenz, Scott, Robert, Scott, Rodney, Sever, Peter, Spector, Tim D., van der Harst, Pim, Wareham, Nicholas J., Zeggini, Eleftheria, Levy, Daniel, Munroe, Patricia B., Newton-Cheh, Christopher, Brown, Morris J., Metspalu, Andres, Hung, Adriana M., O'Donnell, Christopher, Edwards, Todd L., Psaty, Bruce M., Tzoulaki, Ioanna, Barnes, Michael R., Wain, Louise V., Elliott, Paul, and Caulfield, Mark J.
Abstract: High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic, pulse pressure) to date in over one million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also reveal shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.
Published: 2018

47. Nutrient profiling and adherence to components of the UK national dietary guidelines association with metabolic risk factors for CVD and diabetes: Airwave Health Monitoring Study

Author: Eriksen, Rebeca, primary, Gibson, Rachel, additional, Lamb, Kathryn, additional, McMeel, Yvonne, additional, Vergnaud, Anne-Claire, additional, Spear, Jeanette, additional, Aresu, Maria, additional, Chan, Queenie, additional, Elliott, Paul, additional, and Frost, Gary, additional
Published: 2018
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48. Main nutrient patterns are associated with prospective weight change in adults from 10 European countries

Author: Freisling, Heinz Pisa, Pedro T. Ferrari, Pietro Byrnes, Graham Moskal, Aurelie Dahm, Christina C. Vergnaud, Anne-Claire Boutron-Ruault, Marie-Christine Fagherazzi, Guy and Cadeau, Claire Kuehn, Tilman Neamat-Allah, Jasmine Buijsse, Brian Boeing, Heiner Halkjaer, Jytte Tjonneland, Anne and Hansen, Camilla P. Ramon Quiros, J. Travier, Noemie and Molina-Montes, Esther Amiano, Pilar Huerta, Jose M. and Barricarte, Aurelio Khaw, Kay-Tee Wareham, Nicholas Key, Tim J. Romaguera, Dora Lu, Yunxia Lassale, Camille M. Naska, Androniki Orfanos, Philippos Trichopoulou, Antonia Masala, Giovanna Pala, Valeria Berrino, Franco Tumino, Rosario and Ricceri, Fulvio de Magistris, Maria Santucci Bueno-de-Mesquita, H. Bas Ocke, Marga C. Sonestedt, Emily Ericson, Ulrika and Johansson, Mattias Skeie, Guri Weiderpass, Elisabete and Braaten, Tonje Peeters, Petra H. M. Slimani, Nadia
Abstract: Various food patterns have been associated with weight change in adults, but it is unknown which combinations of nutrients may account for such observations. We investigated associations between main nutrient patterns and prospective weight change in adults. This study includes 235,880 participants, 25-70 years old, recruited between 1992 and 2000 in 10 European countries. Intakes of 23 nutrients were estimated from country-specific validated dietary questionnaires using the harmonized EPIC Nutrient DataBase. Four nutrient patterns, explaining 67 % of the total variance of nutrient intakes, were previously identified from principal component analysis. Body weight was measured at recruitment and self-reported 5 years later. The relationship between nutrient patterns and annual weight change was examined separately for men and women using linear mixed models with random effect according to center controlling for confounders. Mean weight gain was 460 g/year (SD 950) and 420 g/year (SD 940) for men and women, respectively. The annual differences in weight gain per one SD increase in the pattern scores were as follows: principal component (PC) 1, characterized by nutrients from plant food sources, was inversely associated with weight gain in men (-22 g/year; 95 % CI -33 to -10) and women (-18 g/year; 95 % CI -26 to -11). In contrast, PC4, characterized by protein, vitamin B2, phosphorus, and calcium, was associated with a weight gain of +41 g/year (95 % CI +2 to +80) and +88 g/year (95 % CI +36 to +140) in men and women, respectively. Associations with PC2, a pattern driven by many micro-nutrients, and with PC3, a pattern driven by vitamin D, were less consistent and/or non-significant. We identified two main nutrient patterns that are associated with moderate but significant long-term differences in weight gain in adults.
Published: 2016

49. A cross-sectional investigation into the occupational and socio-demographic characteristics of British police force employees reporting a dietary pattern associated with cardiometabolic risk: findings from the Airwave Health Monitoring Study

Author: Gibson, Rachel, primary, Eriksen, Rebeca, additional, Singh, Deepa, additional, Vergnaud, Anne-Claire, additional, Heard, Andrew, additional, Chan, Queenie, additional, Elliott, Paul, additional, and Frost, Gary, additional
Published: 2017
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50. Dietary assessment of British police force employees: a description of diet record coding procedures and cross-sectional evaluation of dietary energy intake reporting (The Airwave Health Monitoring Study)

Author: Gibson, Rachel, primary, Eriksen, Rebeca, additional, Lamb, Kathryn, additional, McMeel, Yvonne, additional, Vergnaud, Anne-Claire, additional, Spear, Jeanette, additional, Aresu, Maria, additional, Chan, Queenie, additional, Elliott, Paul, additional, and Frost, Gary, additional
Published: 2017
Full Text: View/download PDF

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