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6. GRADE: Assessing the quality of evidence in environmental and occupational health

Author

Morgan, Rebecca L, Thayer, Kristina A, Bero, Lisa, Bruce, Nigel, Falck-Ytter, Yngve, Ghersi, Davina, Guyatt, Gordon, Hooijmans, Carlijn, Langendam, Miranda, Mandrioli, Daniele, Mustafa, Reem A, Rehfuess, Eva A, Rooney, Andrew A, Shea, Beverley, Silbergeld, Ellen K, Sutton, Patrice, Wolfe, Mary S, Woodruff, Tracey J, Verbeek, Jos H, Holloway, Alison C, Santesso, Nancy, and Schünemann, Holger J

Subjects
Commerce, Management, Tourism and Services, Human Resources and Industrial Relations, Health Sciences, Clinical Research, Prevention, Aetiology, 2.2 Factors relating to the physical environment, Generic health relevance, Environmental Health, Epidemiologic Research Design, Evidence-Based Medicine, Humans, Occupational Health, Reproducibility of Results, Review Literature as Topic, GRADE, Evidence-based, Risk of bias, Environmental health, Risk assessment, Recommendations, Environmental Sciences
Abstract

There is high demand in environmental health for adoption of a structured process that evaluates and integrates evidence while making decisions and recommendations transparent. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework holds promise to address this demand. For over a decade, GRADE has been applied successfully to areas of clinical medicine, public health, and health policy, but experience with GRADE in environmental and occupational health is just beginning. Environmental and occupational health questions focus on understanding whether an exposure is a potential health hazard or risk, assessing the exposure to understand the extent and magnitude of risk, and exploring interventions to mitigate exposure or risk. Although GRADE offers many advantages, including its flexibility and methodological rigor, there are features of the different sources of evidence used in environmental and occupational health that will require further consideration to assess the need for method refinement. An issue that requires particular attention is the evaluation and integration of evidence from human, animal, in vitro, and in silico (computer modeling) studies when determining whether an environmental factor represents a potential health hazard or risk. Assessment of the hazard of exposures can produce analyses for use in the GRADE evidence-to-decision (EtD) framework to inform risk-management decisions about removing harmful exposures or mitigating risks. The EtD framework allows for grading the strength of the recommendations based on judgments of the certainty in the evidence (also known as quality of the evidence), as well as other factors that inform recommendations such as social values and preferences, resource implications, and benefits. GRADE represents an untapped opportunity for environmental and occupational health to make evidence-based recommendations in a systematic and transparent manner. The objectives of this article are to provide an overview of GRADE, discuss GRADE's applicability to environmental health, and identify priority areas for method assessment and development.

Published
2016

8. Effectiveness of Interventions for Preventing Injuries in the Construction Industry: Results of an Updated Cochrane Systematic Review

Author

van der Molen, Henk F., Basnet, Prativa, Hoonakker, Peter L. T., Lehtola, Marika M., Lappalainen, Jorma, Frings-Dresen, Monique H. W., Haslam, Roger A., Verbeek, Jos H., Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Bagnara, Sebastiano, editor, Tartaglia, Riccardo, editor, Albolino, Sara, editor, Alexander, Thomas, editor, and Fujita, Yushi, editor

Published
2019
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9. Which outcomes should always be measured in intervention studies for improving work participation for people with a health problem? An international multistakeholder Delphi study to develop a core outcome set for Work participation (COS for Work)

Author

Ravinskaya, Margarita, Verbeek, Jos H, Langendam, Miranda, Madan, Ira, Verstappen, Suzanne M M, Kunz, Regina, Hulshof, Carel T J, Hoving, Jan L, Collaborators, Curti, Stefania, Graduate School, Public and occupational health, APH - Methodology, APH - Societal Participation & Health, Epidemiology and Data Science, APH - Quality of Care, CCA - Cancer Treatment and Quality of Life, Ravinskaya, Margarita, Verbeek, Jos H, Langendam, Miranda, Madan, Ira, Verstappen, Suzanne M M, Kunz, Regina, Hulshof, Carel T J, Hoving, Jan L, Collaborator, and Curti, Stefania

Subjects
occupational & industrial medicine, public health, statistics & research methods, rehabilitation medicine, General Medicine, Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]
Abstract

ObjectiveSynthesising evidence of the effects of interventions to improve work participation among people with health problems is currently difficult due to heterogeneity in outcome measurements. A core outcome set for work participation is needed.Study design and settingFollowing the Core Outcome Measures in Effectiveness Trials methodology, we used a five-step approach to reach international multistakeholder consensus on a core outcome set for work participation. Five subgroups of stakeholders took part in two rounds of discussions and completed two Delphi voting rounds on 26 outcomes. A consensus of ≥80% determined core outcomes and 50%–80% consensus was required for candidate outcomes.ResultsFifty-eight stakeholders took part in the Delphi rounds. Core outcomes were: ‘any type of employment including self-employment’, ‘proportion of workers that return to work after being absent because of illness’ and ‘time to return to work’. Ten candidate outcomes were proposed, among others: ‘sustainable employment’, ‘work productivity’ and ‘workers’ perception of return to work’.ConclusionAs a minimum, all studies evaluating the impact of interventions on work participation should include one employment outcome and two return to work outcomes if workers are on sick leave prior to the intervention.

Published
2023

17. Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings

Author

Pizarro, Ana Beatriz, additional, Persad, Emma, additional, Durao, Solange, additional, Nussbaumer-Streit, Barbara, additional, Engela-Volker, Jean S, additional, McElvenny, Damien, additional, Rhodes, Sarah, additional, Stocking, Katie, additional, Fletcher, Tony, additional, Martin, Craig, additional, Noertjojo, Kukuh, additional, Sampson, Olivia, additional, Verbeek, Jos H, additional, Jørgensen, Karsten Juhl, additional, and Bruschettini, Matteo, additional

Published
2022
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19. Legal banning of asbestos for preventing asbestos exposure

Author

Belackova, Lea, Verbeek, Jos H, Hoving, Jan L, Molen, Henk F, Gagliardi, Diana, Curti, Stefania, Hulshof, Carel TJ, Scheepers, Paul TJ, and Marinaccio, Alessandro

Subjects
Pharmacology (medical), health care economics and organizations
Abstract

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effect of a legal ban of asbestos on the time trend of production, import and use of asbestos and exposure to asbestos among workers or the general population, compared to the time trend when there was not such a ban.

Published
2022

22. Potential importance of residual confounding in systematic reviews of observational studies: Answer to Mathur and VanderTweele

Author

Verbeek, Jos H., primary, Whaley, Paul, additional, Morgan, Rebecca L., additional, Taylor, Kyla W., additional, Rooney, Andrew A., additional, Schwingshackl, Lukas, additional, Hoving, Jan L., additional, Vittal Katikireddi, S., additional, Shea, Beverley, additional, Mustafa, Reem A., additional, Murad, M.Hassan, additional, and Schünemann, Holger J., additional

Published
2022
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29. An approach to quantifying the potential importance of residual confounding in systematic reviews of observational studies: A GRADE concept paper

Author

Verbeek, Jos H., primary, Whaley, Paul, additional, Morgan, Rebecca L., additional, Taylor, Kyla W., additional, Rooney, Andrew A., additional, Schwingshackl, Lukas, additional, Hoving, Jan L., additional, Vittal Katikireddi, S., additional, Shea, Beverley, additional, Mustafa, Reem A., additional, Murad, M. Hassan, additional, and Schünemann, Holger J., additional

Published
2021
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