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1. Sex-specific differences in systemic immune responses in MIS-C children

Author

Rajamanickam, Anuradha, Kumar, Nathella Pavan, Venkataraman, Aishwarya, Varadarjan, Poovazhagi, Selladurai, Elilarasi, Sankaralingam, Thangavelu, Thiruvengadam, Kannan, Selvam, Ramya, Thimmaiah, Akshith, Natarajan, Suresh, Ramaswamy, Ganesh, Putlibai, Sulochana, Sadasivam, Kalaimaran, Sundaram, Balasubramanian, Hissar, Syed, Ranganathan, Uma Devi, and Babu, Subash

Published
2024
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3. Kawasaki Disease in the Time of COVID-19 and MIS-C: The International Kawasaki Disease Registry

Author

Alsalehi, Mahmoud, Ballweg, Jean A., Barnes, Benjamin, Braunlin, Elizabeth, Buffone, Ashley, Bustamante-Ogando, Juan Carlos, Chang, Arthur J., Corral, Nicolas, Dancey, Paul, El-Ganzoury, Mona, El-Samman, Nora, Elias, Matthew, Fernandez-Cooke, Elisa, Friedman, Kevin, Garrido-Garcia, Luis Martin, Garrido, Luis Martin, Goldenberg, Guillermo Larios, Grcic, Michelle M., Harris, Kevin C., Hicar, Mark D., Hindt, Bridgette, Jone, Pei-Ni, Kajimoto, Hidemi, Kaneta, Kelli, Khare, Manaswitha, Knutson, Stacie, Kutty, Shelby, Lanari, Marcello, Maksymiuk, Victoria, McHugh, Kimberly E., Merves, Shae, Misra, Nilanjana, Mohandas, Sindhu, Mondal, Tapas, Norozi, Kambiz, Nowlen, Todd, Pagano, Joseph J., Prasad, Deepa, Raghuveer, Geetha, Ravi, Prasad, Sundaram, Balasubramanian, Sehgal, Anupam, Shah, Ashish, Vázquez, Belén Toral, Tremoulet, Adriana H., Venkataraman, Aishwarya, Watelle, Laurence, Yamazaki-Naksahimada, Marco Antonio, Yetman, Anji T., Harahsheh, Ashraf S., Shah, Samay, Dallaire, Frederic, Manlhiot, Cedric, Khoury, Michael, Lee, Simon, Fabi, Marianna, Mauriello, Daniel, Tierney, Elif Seda Selamet, Sabati, Arash A., Dionne, Audrey, Dahdah, Nagib, Choueiter, Nadine, Thacker, Deepika, Giglia, Therese M., Truong, Dongngan T., Jain, Supriya, Portman, Michael, Orr, William B., Harris, Tyler H., Szmuszkovicz, Jacqueline R., Farid, Pedrom, and McCrindle, Brian W.

Published
2024
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5. Abstract 15506: Pattern of Use of Anakinra for Patients With Kawasaki Disease versus Multisystem Inflammatory Syndrome in Children Associated With COVID-19

Author

Portman, Michael A, Harahsheh, Ashraf S, Raghuveer, Geetha, Sundraram, Balasubramanian, Venkataraman, Aishwarya, Yamazaki-Naksahimada, Marco, Park, Susan, El Ganzoury, Mona, Dionne, Audrey, Thacker, Deepika, Chang, Arthur J, Choueiter, Nadine, Braunlin, Elizabeth A, Orr, William, McHugh, Kimberly E, Farid, Pedrom, Manlhiot, Cedric, and McCrindle, Brian W

Published
2023
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6. Elucidating systemic immune responses to acute and convalescent SARS‐CoV‐2 infection in children and elderly individuals

Author

Rajamanickam, Anuradha, primary, Nathella, Pavan Kumar, additional, Venkataraman, Aishwarya, additional, Chandrasekaran, Padmapriyadarsini, additional, Rajendraprasath, Sasidaran, additional, Devaleenal, Bella D., additional, Pandiarajan, Arul Nancy, additional, Krishnakumar, Gowshika, additional, Venkat Ramanan, Padmasani, additional, and Babu, Subash, additional

Published
2024
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8. Abstract 11816: Association of Increased Adiposity and Presentation and Outcomes for Kawasaki Disease versus Multisystem Inflammatory Syndrome in Children Associated With Covid-19

Author

Khoury, Michael, Venkataraman, Aishwarya, Portman, Michael A, Fabi, Marianna, Dahdah, Nagib, Jain, Supriya, Jone, Pei-Ni, Raghuveer, Geetha, Lee, Simon, Prasad, Deepa, El Ganzoury, Mona, Yetman, Angela T, Friedman, Kevin G, Martin Garrido, Luis, Norozi, Kambiz, Sehgal, Anupam, Serrano, Ryan M, Kutty, Shelby, Farid, Pedrom, and McCrindle, Brian W

Published
2022
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10. Multisystem inflammatory syndrome in children characterized by enhanced antigen-specific T-cell expression of cytokines and its reversal following recovery

Author

Pavan Kumar, Nathella, primary, Abbas, Kadar M., additional, Renji, Rachel M., additional, Venkataraman, Aishwarya, additional, Nancy, Arul, additional, Varadarjan, Poovazhagi, additional, Selladurai, Elilarasi, additional, Sangaralingam, Thankgavelu, additional, Selvam, Ramya, additional, Thimmaiah, Akshith, additional, Natarajan, Suresh, additional, Ramasamy, Ganesh, additional, Hissar, Syed, additional, Ranganathan, Uma Devi, additional, Nutman, Thomas B., additional, and Babu, Subash, additional

Published
2023
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11. Immune Profiles in Multisystem Inflammatory Syndrome in Children with Cardiovascular Abnormalities

Author

Kumar, Nathella Pavan, primary, Venkataraman, Aishwarya, additional, Nancy, Arul, additional, Selvaraj, Nandhini, additional, Moideen, Kadar, additional, Ahamed, Shaik Fayaz, additional, Renji, Rachel Marriam, additional, Sasidaran, Kandasamy, additional, Kumar, Sandip, additional, Periyakuppan, Muthiah, additional, Sangaralingam, Thankgavelu, additional, Varadarajan, Poovazhagi, additional, Chelladurai, Elilarasi, additional, and Babu, Subash, additional

Published
2023
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13. Kawasaki Disease in the Time of COVID-19 and MIS-C: The International Kawasaki Disease Registry

Author

Harahsheh, Ashraf S., primary, Shah, Samay, additional, Dallaire, Frederic, additional, Manlhiot, Cedric, additional, Khoury, Michael, additional, Lee, Simon, additional, Fabi, Marianna, additional, Mauriello, Daniel, additional, Tierney, Elif Seda Selamet, additional, Sabati, Arash A., additional, Dionne, Audrey, additional, Dahdah, Nagib, additional, Choueiter, Nadine, additional, Thacker, Deepika, additional, Giglia, Therese M., additional, Truong, Dongngan T., additional, Jain, Supriya, additional, Portman, Michael, additional, Orr, William B., additional, Harris, Tyler H., additional, Szmuszkovicz, Jacqueline R., additional, Farid, Pedrom, additional, McCrindle, Brian W., additional, Alsalehi, Mahmoud, additional, Ballweg, Jean A., additional, Barnes, Benjamin, additional, Braunlin, Elizabeth, additional, Buffone, Ashley, additional, Bustamante-Ogando, Juan Carlos, additional, Chang, Arthur J., additional, Corral, Nicolas, additional, Dancey, Paul, additional, El-Ganzoury, Mona, additional, El-Samman, Nora, additional, Elias, Matthew, additional, Fernandez-Cooke, Elisa, additional, Friedman, Kevin, additional, Garrido-Garcia, Luis Martin, additional, Garrido, Luis Martin, additional, Goldenberg, Guillermo Larios, additional, Grcic, Michelle M., additional, Harris, Kevin C., additional, Hicar, Mark D., additional, Hindt, Bridgette, additional, Jone, Pei-Ni, additional, Kajimoto, Hidemi, additional, Kaneta, Kelli, additional, Khare, Manaswitha, additional, Knutson, Stacie, additional, Kutty, Shelby, additional, Lanari, Marcello, additional, Maksymiuk, Victoria, additional, McHugh, Kimberly E., additional, Merves, Shae, additional, Misra, Nilanjana, additional, Mohandas, Sindhu, additional, Mondal, Tapas, additional, Norozi, Kambiz, additional, Nowlen, Todd, additional, Pagano, Joseph J., additional, Prasad, Deepa, additional, Raghuveer, Geetha, additional, Ravi, Prasad, additional, Sundaram, Balasubramanian, additional, Sehgal, Anupam, additional, Shah, Ashish, additional, Vázquez, Belén Toral, additional, Tremoulet, Adriana H., additional, Venkataraman, Aishwarya, additional, Watelle, Laurence, additional, Yamazaki-Naksahimada, Marco Antonio, additional, and Yetman, Anji T., additional

Published
2023
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14. Multisystem inflammatory syndrome in children characterized by enhanced antigen-specific T-cell expression of cytokines and its reversal following recovery.

Author

Kumar, Nathella Pavan, Abbas, Kadar M., Renji, Rachel M., Venkataraman, Aishwarya, Nancy, Arul, Varadarjan, Poovazhagi, Selladurai, Elilarasi, Sangaralingam, Thankgavelu, Selvam, Ramya, Thimmaiah, Akshith, Natarajan, Suresh, Ramasamy, Ganesh, Hissar, Syed, Ranganathan, Uma Devi, Nutman, Thomas B., and Babu, Subash

Published
2023
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17. Role of matrix metalloproteinases in multi-system inflammatory syndrome and acute COVID-19 in children

Author

Pavan Kumar, Nathella, primary, Venkataraman, Aishwarya, additional, Varadarjan, Poovazhagi, additional, Nancy, Arul, additional, Rajamanickam, Anuradha, additional, Selladurai, Elilarasi, additional, Sankaralingam, Thangavelu, additional, Thiruvengadam, Kannan, additional, Selvam, Ramya, additional, Thimmaiah, Akshith, additional, Natarajan, Suresh, additional, Ramaswamy, Ganesh, additional, Putlibai, Sulochana, additional, Sadasivam, Kalaimaran, additional, Sundaram, Balasubramanian, additional, Hissar, Syed, additional, Ranganathan, Uma Devi, additional, Nutman, Thomas B., additional, and Babu, Subash, additional

Published
2022
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18. Comparison of two mycobacterial strains in performance of the whole blood mycobacterial growth inhibition assay in Indian children

Author

Venkataraman, Aishwarya, primary, Shanmugam, Sivakumar, additional, Balaji, Sarath, additional, Mani, Karthick, additional, Shanmugavel, Ashok Kumar, additional, Muthuramalingam, Kannan, additional, Hissar, Syed, additional, Thiruvengadam, Kannan, additional, Selladurai, Elilarasi, additional, Smuk, Melanie, additional, Hanna, Luke Elizabeth, additional, and Prendergast, Andrew J., additional

Published
2022
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19. Unique cellular immune signatures of multisystem inflammatory syndrome in children

Author

Rajamanickam, Anuradha, primary, Nathella, Pavan Kumar, additional, Venkataraman, Aishwarya, additional, Varadarjan, Poovazhagi, additional, Kannan, Srinithi, additional, Pandiarajan, Arul Nancy, additional, Renji, Rachel Mariam, additional, Elavarasan, Elayarani, additional, Thimmaiah, Akshith, additional, Sasidaran, Kandasamy, additional, Krishnamoorthy, Nedunchelian, additional, Natarajan, Suresh, additional, Ramaswamy, Ganesh, additional, Sundaram, Balasubramanian, additional, Putlibai, Sulochana, additional, Hissar, Syed, additional, Selladurai, Elilarasi, additional, Uma Devi, K. Ranganathan, additional, Nutman, Thomas B., additional, and Babu, Subash, additional

Published
2022
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20. Enhanced Severe Acute Respiratory Syndrome Coronavirus 2 Antigen–Specific Systemic Immune Responses in Multisystem Inflammatory Syndrome in Children and Reversal After Recovery

Author

Kumar, Nathella Pavan, primary, Venkataraman, Aishwarya, additional, Nancy, Arul, additional, Moideen, Kadar, additional, Varadarjan, Poovazhagi, additional, Selladurai, Elilarasi, additional, Sangaralingam, Thankgavelu, additional, Selvam, Ramya, additional, Thimmaiah, Akshith, additional, Natarajan, Suresh, additional, Ramasamy, Ganesh, additional, Hissar, Syed, additional, Radayam Ranganathan, Umadevi, additional, and Babu, Subash, additional

Published
2022
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21. Systemic Inflammation and Microbial Translocation Are Characteristic Features of SARS-CoV-2-Related Multisystem Inflammatory Syndrome in Children

Author

Kumar, Nathella Pavan, primary, Venkataraman, Aishwarya, additional, Hanna, Luke Elizabeth, additional, Putlibai, Sulochana, additional, Karthick, M, additional, Rajamanikam, Anuradha, additional, Sadasivam, Kalaimaran, additional, Sundaram, Balasubramanian, additional, and Babu, Subash, additional

Published
2021
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22. Correlation of SARS-CoV-2 serology and clinical phenotype amongst hospitalised children in a tertiary children’s hospital in India

Author

Venkataraman, Aishwarya, primary, Balasubramanian, S, additional, Putilibai, Sulochana, additional, Lakshan Raj, S, additional, Amperayani, Sumanth, additional, Senthilnathan, S, additional, Manoharan, Anand, additional, Sophi, Arokia, additional, Amutha, R, additional, Sadasivam, Kalaimaran, additional, Goenka, Anu, additional, and Ramanan, A V, additional

Published
2021
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23. Analyzing the flash crossdomain policies

Author

Venkataraman, Aishwarya

Subjects
UCSD Dissertations, Academic Computer science. (Discipline)
Abstract

Adobe Flash is a multimedia platform used for developing rich internet applications. Flash also facilitates sharing resources and data between flash files on different domains. Sites that allow sharing of content need to host a crossdomain policy file, crossdomain.xml which has a list of websites that can access resources from this site. This thesis attempts to survey the crossdomain.xml Flash policy file present accross the Alexa top 50,000 websites. We found that 3609 out of the 47197 surveyed sites had unrestricted crossdomain Flash access. These numbers suggest that Flash crossdomain.xml policy files are liable to misconfiguration. We also propose some mitigation techniques for the same

Published
2012

24. Correlation of SARS-CoV-2 Serology and Clinical Phenotype Amongst Hospitalised Children in a Tertiary Children's Hospital in India.

Author

Venkataraman, Aishwarya, Balasubramanian, S, Putilibai, Sulochana, Raj, S Lakshan, Amperayani, Sumanth, Senthilnathan, S, Manoharan, Anand, Sophi, Arokia, Amutha, R, Sadasivam, Kalaimaran, Goenka, Anu, Ramanan, A V, and Lakshan Raj, S

Subjects
*CHILDREN'S hospitals, *SARS-CoV-2, *COVID-19, *COVID-19 pandemic, *SEROLOGY
Abstract

Introduction: Children usually present with minimal or no symptoms of COVID-19 infection. Antibody responses to SARS-CoV-2 in children from low- and middle-income countries (LMIC) have not been well described. We describe the prevalence of anti-SARS-CoV-2 antibodies and clinical phenotype of seropositive children admitted to a tertiary children's hospital in South India.Methods: To determine the seropositivity and describe the clinical characteristics of COVID-19 infection amongst hospitalised children, we performed a prospective clinical data collection and blood sampling of children admitted to Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India over 4 months of the COVID-19 pandemic. In seropositive children, we compared antibody titres between children with and without PIMS-TS.Results: Of 463 children, 91 (19.6%) were seropositive. The median (range) age of seropositive children was 5 years (1 month-17 years). Clinical presentation was consistent with Paediatric inflammatory multisystem syndrome associated or related with SARS-CoV-2 infection (PIMS-TS) in 48% (44/91) of seropositive children. The median (range) antibody titre was 54.8 (11.1-170.9) AU/ml among all seropositive children. The median antibody titre among the children with PIMS-TS (60.3 AU/mL) was significantly (p = 0.01) higher when compared to the children without PIMS-TS (54.8 AU/mL).Conclusion: We describe the antibody responses to SARS-CoV-2 amongst hospitalised children in a LMIC tertiary children's hospital. Almost half of the seropositive children had PIMS-TS. Antibody levels may be helpful in the diagnosis and disease stratification of PIMS-TS.Lay Summary: Children usually present with minimal or no symptoms of COVID-19 infection. However, Multisystem Inflammatory Syndrome in Children (MIS-C) or Paediatric inflammatory multisystem syndrome associated or related with SARS-CoV-2 infection (PIMS-TS) has emerged as a distinctive paediatric illness related to SARS-CoV-2. Recently, antibody testing for SARS-CoV-2 is being used increasingly as a diagnostic test for PIMS-TS. However, data on the antibody responses to SARS-CoV-2 in children are sparse. We, therefore, attempted to identify the seropositivity and describe the clinical spectrum of COVID-19 infection amongst infants and children getting hospitalised in a children's hospital in south India. Nearly one-fifth of the hospitalised children tested serology positive over 4 months. Antibody levels in children with PIMS-TS were significantly higher in comparison to the other two groups (acute COVID-19 infection and children without PIMS-TS). Results from our study suggest that all children are at risk of COVID-19 infection though they may present with mild illness or no symptoms. We also observed that antibody testing may have a possible role in diagnosis of PIMS-TS. [ABSTRACT FROM AUTHOR]

Published
2021
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29. Pediatric Resuscitation

Author

Avanis, Mary Claire, primary, Venkataraman, Aishwarya, additional, Vaidya, Mamta, additional, and Sadasivam, Kalaimaran, additional

Published
2016
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36. Defragmentation of Resources in Virtual Desktop Clouds for Cost-Aware Utility-Maximal Allocation

Author

Venkataraman, Aishwarya

Subjects
Computer Science
Abstract

Cloud Service Providers (CSPs) make virtual desktop cloud (VDC) resource provisioning decisions within desktop pools based on user groups and their application profiles. Such provisioning is aimed to not only satisfy acceptable user quality of experience (QoE) levels and provide high scalability, but also provide "knobs" to CSPs to operate according their economic policies. The next challenge is to place user VD requests in an optimal and fast manner across distributed data centers. The placement decisions are influenced by session latency, load balancing and operation cost constraints. In this work, we identify the resource fragmentation problem that occurs when placement is done opportunistically to minimize provisioning time and deliver satisfactory user QoE. To solve this problem, which inherently is an NP-Hard problem, we propose a defragmentation scheme that has fast convergence time and has three levels of complexity: (i) "Economics-directed resource allocation model"(E-RAM) that considers economic policies while optimizing resource provisioning within a data center (ii) "Cost-aware Utility-maximal Local Placement" to optimize resource provisioning between multiple data centers, and (iii) "Cost-aware Utility-maximal Global Placement with Migration" to optimize resource provisioning using cost-aware and utility-maximal VD re-allocations and migrations - to increase scalability and performance. We evaluate our E-RAM, Cost-aware Utility-maximal Local and Global Placement schemes using a novel "VDC-Sim" simulator that we have developed in this study. Our simulations leverage profiles of user groups and their applications within desktop pools, obtained from a real VDC testbed. We also implemented our schemes in a real cloud infrastructure. Our results demonstrate that defragmentation is an important optimization step and defragmentation together with E-RAM and our Cost-aware Utility-maximal placement schemes can enable CSPs to achieve optimal user QoE, higher VDC scalability, improved system performance and resilience.

Published
2012

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