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1. Relative Measurement and Extrapolation of the Scintillation Quenching Factor of $\alpha$-Particles in Liquid Argon using DEAP-3600 Data

Author

The DEAP Collaboration, Adhikari, P., Alpízar-Venegas, M., Amaudruz, P. -A., Anstey, J., Auty, D. J., Batygov, M., Beltran, B., Bina, C. E., Bonivento, W., Boulay, M. G., Bueno, J. F., Cai, B., Cárdenas-Montes, M., Choudhary, S., Cleveland, B. T., Crampton, R., Daugherty, S., DelGobbo, P., Di Stefano, P., Dolganov, G., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Ford, R. J., Gahan, D., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Giménez-Alcázar, A., Goeldi, D., Gorel, P., Graham, K., Hallin, A. L., Hamstra, M., Haskins, S., Hu, J., Hucker, J., Hugues, T., Ilyasov, A., Jigmeddorj, B., Jillings, C. J., Kaur, G., Kemp, A., Kuźniak, M., La Zia, F., Lai, M., Langrock, S., Lehnert, B., Levashko, N., Lissia, M., Luzzi, L., Machulin, I., Maru, A., Mason, J., McDonald, A. B., McElroy, T., McLaughlin, J. B., Mielnichuk, C., Mirasola, L., Monroe, J., Ng, C., Oliviéro, G., Pal, S., Papi, D., Perry, M., Pesudo, V., Pollmann, T. R., Rad, F., Rethmeier, C., Retière, F., Roszkowski, L., Santorelli, R., Schuckman II, F. G., Seth, S., Shalamova, V., Skensved, P., Smirnova, T., Sobotkiewich, K., Sonley, T., Sosiak, J., Soukup, J., Stainforth, R., Stringer, M., Tang, J., Vázquez-Jáuregui, E., Viel, S., Vyas, B., Walczak, M., Walding, J., Ward, M., and Westerdale, S.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The knowledge of scintillation quenching of $\alpha$-particles plays a paramount role in understanding $\alpha$-induced backgrounds and improving the sensitivity of liquid argon-based direct detection of dark matter experiments. We performed a relative measurement of scintillation quenching in the MeV energy region using radioactive isotopes ($^{222}$Rn, $^{218}$Po and $^{214}$Po isotopes) present in trace amounts in the DEAP-3600 detector and quantified the uncertainty of extrapolating the quenching factor to the low-energy region., Comment: Submitted to Eur. Phys. J. C

Published
2024

2. Precision Measurement of the Specific Activity of $^{39}$Ar in Atmospheric Argon with the DEAP-3600 Detector

Author

Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Amaudruz, P. -A., Anstey, J., Araujo, G. R., Auty, D. J., Baldwin, M., Batygov, M., Beltran, B., Benmansour, H., Bina, C. E., Bonatt, J., Bonivento, W., Boulay, M. G., Broerman, B., Bueno, J. F., Burghardt, P. M., Butcher, A., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, M., Chen, Y., Choudhary, S., Cleveland, B. T., Corning, J. M., Crampton, R., Cranshaw, D., Daughtery, S., DelGobbo, P., Dering, K., Di Stefano, P., DiGioseffo, J., Dolganov, G., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Florian, S., Flower, A., Ford, R. J., Gagnon, R., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Giménez-Alcázar, A., Goeldi, D., Golovko, V. V., Gorel, P., Graham, K., Grant, D. R., Grobov, A., Hallin, A. L., Hamstra, M., Harvey, P. J., Haskins, S., Hearns, C., Hu, J., Hucker, J., Hugues, T., Ilyasov, A., Jigmeddorj, B., Jillings, C. J., Joy, A., Kamaev, O., Kaur, G., Kemp, A., Kuźniak, M., La Zia, F., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., LePage-Bourbonnais, J., Levashko, N., Lidgard, J., Lindner, T., Lissia, M., Lock, J., Machulin, I., Majewski, P., Maru, A., Mason, J., McDonald, A. B., McElroy, T., McGinn, T., McLaughlin, J. B., Mehdiyev, R., Mielnichuk, C., Mirasola, L., Monroe, J., Nadeau, P., Nantais, C., Ng, C., Noble, A. J., O'Dwyer, E., Oliviéro, G., Ouellet, C., Pal, S., Papi, D., Pasuthip, P., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M. -C., Pollmann, T. R., Rad, F., Rand, E. T., Rethmeier, C., Retière, F., García, I. Rodríguez, Roszkowski, L., Ruhland, J. B., Santorelli, R., Schuckman II, F. G., Seeburn, N., Seth, S., Shalamova, V., Singhrao, K., Skensved, P., Smith, N. J. T., Smith, B., Sobotkiewich, K., Sonley, T., Sosiak, J., Soukup, J., Stainforth, R., Stone, C., Strickland, V., Stringer, M., Sur, B., Tang, J., Vázquez-Jáuregui, E., Veloce, L., Viel, S., Vyas, B., Walczak, M., Walding, J., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The specific activity of the beta decay of $^{39}$Ar in atmospheric argon is measured using the DEAP-3600 detector. DEAP-3600, located 2 km underground at SNOLAB, uses a total of (3269 $\pm$ 24) kg of liquid argon distilled from the atmosphere to search for dark matter. This detector with very low background uses pulseshape discrimination to differentiate between nuclear recoils and electron recoils and is well-suited to measure the decay of $^{39}$Ar. With 167 live-days of data, the measured specific activity at the time of atmospheric extraction is [0.964 $\pm$ 0.001 (stat) $\pm$ 0.024 (sys)] Bq/kg$_{\rm atmAr}$ which is consistent with results from other experiments. A cross-check analysis using different event selection criteria provides a consistent result.

Published
2023
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3. First direct detection constraints on Planck-scale mass dark matter with multiple-scatter signatures using the DEAP-3600 detector

Author

Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Auty, D. J., Benmansour, H., Bina, C. E., Bonivento, W., Boulay, M. G., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, Y., Cleveland, B. T., Corning, J. M., Daugherty, S., DelGobbo, P., Di Stefano, P., Doria, L., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Goeldi, D., Gorel, P., Graham, K., Grobov, A., Hallin, A. L., Hamstra, M., Hugues, T., Ilyasov, A., Joy, A., Jigmeddorj, B., Jillings, C. J., Kamaev, O., Kaur, G., Kemp, A., Kochanek, I., Ku{ź}niak, M., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., Levashko, N., Li, X., Lissia, M., Litvinov, O., Lock, J., Longo, G., Machulin, I., McDonald, A. B., McElroy, T., McLaughlin, J. B., Mielnichuk, C., Mirasola, L., Monroe, J., Oliviéro, G., Pal, S., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M. -C., Pollmann, T. R., Raj, N., Rand, E. T., Rethmeier, C., Retière, F., Rodríguez-García, I., Roszkowski, L., Ruhland, J. B., García, E. Sanchez, Sánchez-Pastor, T., Santorelli, R., Seth, S., Sinclair, D., Skensved, P., Smith, B., Smith, N. J. T., Sonley, T., Stainforth, R., Stringer, M., Sur, B., Vázquez-Jáuregui, E., Viel, S., Walding, J., Waqar, M., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

Dark matter particles with Planck-scale mass ($\simeq10^{19}\text{GeV}/c^2$) arise in well-motivated theories and could be produced by several cosmological mechanisms. Using a blind analysis of data collected over a 813 d live time with DEAP-3600, a 3.3 t single-phase liquid argon-based dark matter experiment at SNOLAB, a search for supermassive dark matter was performed, looking for multiple-scatter signals. No candidate signal events were observed, leading to the first direct detection constraints on Planck-scale mass dark matter. Leading limits constrain dark matter masses between $8.3\times10^{6}$ and $1.2\times10^{19} \text{GeV}/c^2$, and cross sections for scattering on $^{40}$Ar between $1.0\times10^{-23}$ and $2.4\times10^{-18} \text{cm}^2$. These are used to constrain two composite dark matter models.

Published
2021
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5. Pulseshape discrimination against low-energy Ar-39 beta decays in liquid argon with 4.5 tonne-years of DEAP-3600 data

Author

The DEAP Collaboration, Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Amaudruz, P. -A., Auty, D. J., Batygov, M., Beltran, B., Benmansour, H., Bina, C. E., Bonatt, J., Bonivento, W., Boulay, M. G., Broerman, B., Bueno, J. F., Burghardt, P. M., Butcher, A., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, M., Chen, Y., Cleveland, B. T., Corning, J. M., Cranshaw, D., Daugherty, S., DelGobbo, P., Dering, K., DiGioseffo, J., Di Stefano, P., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Florian, S., Flower, T., Ford, R. J., Gagnon, R., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Goeldi, D., Golovko, V., Gorel, P., Graham, K., Grant, D. R., Grobov, A., Hallin, A. L., Hamstra, M., Harvey, P. J., Hearns, C., Hugues, T., Ilyasov, A., Joy, A., Jigmeddorj, B., Jillings, C. J., Kamaev, O., Kaur, G., Kemp, A., Kochanek, I., Kuźniak, M., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., Levashko, N., Li, X., Lidgard, J., Lindner, T., Lissia, M., Lock, J., Longo, G., Machulin, I., McDonald, A. B., McElroy, T., McGinn, T., McLaughlin, J. B., Mehdiyev, R., Mielnichuk, C., Monroe, J., Nadeau, P., Nantais, C., Ng, C., Noble, A. J., O'Dwyer, E., Oliviéro, G., Ouellet, C., Pal, S., Pasuthip, P., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M. -C., Pollmann, T. R., Rand, E. T., Rethmeier, C., Retière, F., Rodríguez-García, I., Roszkowski, L., Ruhland, J. B., Sánchez-García, E., Santorelli, R., Sinclair, D., Skensved, P., Smith, B., Smith, N. J. T., Sonley, T., Soukup, J., Stainforth, R., Stone, C., Strickland, V., Stringer, M., Sur, B., Tang, J., Vázquez-Jáuregui, E., Viel, S., Walding, J., Waqar, M., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The DEAP-3600 detector searches for the scintillation signal from dark matter particles scattering on a 3.3 tonne liquid argon target. The largest background comes from $^{39}$Ar beta decays and is suppressed using pulseshape discrimination (PSD). We use two types of PSD algorithm: the prompt-fraction, which considers the fraction of the scintillation signal in a narrow and a wide time window around the event peak, and the log-likelihood-ratio, which compares the observed photon arrival times to a signal and a background model. We furthermore use two algorithms to determine the number of photons detected at a given time: (1) simply dividing the charge of each PMT pulse by the charge of a single photoelectron, and (2) a likelihood analysis that considers the probability to detect a certain number of photons at a given time, based on a model for the scintillation pulseshape and for afterpulsing in the light detectors. The prompt-fraction performs approximately as well as the log-likelihood-ratio PSD algorithm if the photon detection times are not biased by detector effects. We explain this result using a model for the information carried by scintillation photons as a function of the time when they are detected., Comment: 14 pages, 9 figures

Published
2021
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6. Asymmetric free spaces and canonical asymmetrizations

Author

Daniilidis, Aris, Sepulcre, Juan Matías, and Venegas, M Francisco

Subjects
Mathematics - Functional Analysis, 46B20, 39B82, 46A22
Abstract

A construction analogous to that of Godefroy-Kalton for metric spaces allows to embed isometrically, in a canonical way, every quasi-metric space $(X,d)$ to an asymmetric normed space $\mathcal{F}_a(X,d)$ (its quasi-metric free space, also called asymmetric free space or semi-Lipschitz free space). The quasi-metric free space satisfies a universal property (linearization of semi-Lipschitz functions). The (conic) dual of $\mathcal{F}_a(X,d)$ coincides with the nonlinear asymmetric dual of $(X,d)$, that is, the space $\mathrm{SLip}_0(X,d)$ of semi-Lipschitz functions on $(X,d)$, vanishing at a base point. In particular, for the case of a metric space $(X,D)$, the above construction yields its usual free space. On the other hand, every metric space $(X,D)$ inherits naturally a canonical asymmetrization coming from its free space $\mathcal{F}(X)$. This gives rise to a quasi-metric space $(X,D_+)$ and an asymmetric free space $\mathcal{F}_a(X,D_+)$. The symmetrization of the latter is isomorphic to the original free space $\mathcal{F}(X)$. The results of this work are illustrated with explicit examples., Comment: 33 pages. Updated to published version

Published
2020

11. Diabetic neuropathy: Molecular approach a treatment opportunity

Author

Méndez-Morales, S.T., Pérez-De Marcos, J.C., Rodríguez-Cortés, O., Flores-Mejía, R., Martínez-Venegas, M., Sánchez-Vera, Y., Tamay-Cach, F., Lomeli-Gonzaléz, J., Emilio Reyes, A., Lehman-Mendoza, R., Martínez-Arredondo, H.A., Vazquez-Dávila, R.A., Torres-Roldan, J.F., Correa-Basurto, J., and Arellano-Mendoza, M.G.

Published
2022
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20. Pulse-shape discrimination against low-energy Ar-39 beta decays in liquid argon with 4.5 tonne-years of DEAP-3600 data

Author

Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Amaudruz, P.-A., Auty, D. J., Batygov, M., Beltran, B., Benmansour, H., Bina, C. E., Bonatt, J., Bonivento, W., Boulay, M. G., Broerman, B., Bueno, J. F., Burghardt, P. M., Butcher, A., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, M., Chen, Y., Cleveland, B. T., Corning, J. M., Cranshaw, D., Daugherty, S., DelGobbo, P., Dering, K., DiGioseffo, J., Di Stefano, P., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Florian, S., Flower, T., Ford, R. J., Gagnon, R., Gallacher, D., García Abia, P., Garg, S., Giampa, P., Goeldi, D., Golovko, V., Gorel, P., Graham, K., Grant, D. R., Grobov, A., Hallin, A. L., Hamstra, M., Harvey, P. J., Hearns, C., Hugues, T., Ilyasov, A., Joy, A., Jigmeddorj, B., Jillings, C. J., Kamaev, O., Kaur, G., Kemp, A., Kochanek, I., Kuźniak, M., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., Levashko, N., Li, X., Lidgard, J., Lindner, T., Lissia, M., Lock, J., Longo, G., Machulin, I., McDonald, A. B., McElroy, T., McGinn, T., McLaughlin, J. B., Mehdiyev, R., Mielnichuk, C., Monroe, J., Nadeau, P., Nantais, C., Ng, C., Noble, A. J., O’Dwyer, E., Oliviéro, G., Ouellet, C., Pal, S., Pasuthip, P., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M.-C., Pollmann, T. R., Rand, E. T., Rethmeier, C., Retière, F., Rodríguez-García, I., Roszkowski, L., Ruhland, J. B., Sánchez-García, E., Santorelli, R., Sinclair, D., Skensved, P., Smith, B., Smith, N. J. T., Sonley, T., Soukup, J., Stainforth, R., Stone, C., Strickland, V., Stringer, M., Sur, B., Tang, J., Vázquez-Jáuregui, E., Viel, S., Walding, J., Waqar, M., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.

Published
2021
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28. Estenosis aórtica de bajo flujo y bajo gradiente

Author

José Luis Zamorano, Jaime Alberto Rodríguez P., and Miguel Venegas M.

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Resumen: La estenosis valvular aórtica es la valvulopatía más frecuente y en los últimos años ha sido admirable el avance tanto en su aproximación diagnóstica como terapéutica, dado el advenimiento del reemplazo de válvula aórtica transcatéter y múltiples predictores tanto clínicos, como ecocardiográficos y tomográficos que favorecen la intervención valvular temprana, en una enfermedad que tiene una evolución progresiva.En la actualidad se conoce la estenosis aórtica no como un problema valvular puro; en su evaluación se requiere integrar el denominado complejo ventrículo, valvular y arterial, para comprender los diferentes fenómenos fisiológicos que pueden generar diversos estados de flujo y gradientes. Recientemente, numerosas publicaciones han descrito en detalle la estenosis aórtica de bajo flujo y bajo gradiente, permitiendo aclarar su enfoque diagnóstico, terapéutico y pronóstico que la convierten en un subgrupo especial que se describe a continuación. Abstract: Aortic valve stenosis is the most common valve disease. In the last few years, its diagnostic and therapeutic approach has advanced considerably with the advent of transcatheter aortic valve replacement (TAVR), as well as the many clinical and electrocardiographic and computed tomography predictors that favour an early intervention of the valve in a disease that is progressive.Aortic stenosis is currently known not just as a pure valve problem. In its evaluation it has to include the so-called ventricular, valvular and arterial complex, in order to understand the different physiological phenomena that can generate different flow and gradient states. Recently, many publications have presented detailed accounts of low-flow, low-gradient aortic stenosis, focusing on its diagnostic, therapeutic, and prognostic approach that converts it into a special sub-group as described in the article. Palabras clave: Estenosis aórtica, Área valvular proyectada, Score de calcio, Dobutamina, TAVR, Bajo flujo/bajo gradiente, Keywords: Aortic stenosis, Projected valve area, Calcium score, Dobutamine, TAVR, Low-flow/low-gradient

Published
2019
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37. Precision measurement of the specific activity of 39Ar in atmospheric argon with the DEAP-3600 detector.

Author

Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Amaudruz, P.-A., Anstey, J., Araujo, G. R., Auty, D. J., Baldwin, M., Batygov, M., Beltran, B., Benmansour, H., Bina, C. E., Bonatt, J., Bonivento, W., Boulay, M. G., Broerman, B., Bueno, J. F., Burghardt, P. M., Butcher, A., and Cadeddu, M.

Subjects
LIQUID argon, ARGON, DETECTORS, DARK matter, CONSTRUCTION materials, NEUTRINO detectors
Abstract

The specific activity of the β decay of 39 Ar in atmospheric argon is measured using the DEAP-3600 detector. DEAP-3600, located 2 km underground at SNOLAB, uses a total of (3269 ± 24) kg of liquid argon distilled from the atmosphere to search for dark matter. This detector is well-suited to measure the decay of 39 Ar owing to its very low background levels. This is achieved in two ways: it uses low background construction materials; and it uses pulse-shape discrimination to differentiate between nuclear recoils and electron recoils. With 167 live-days of data, the measured specific activity at the time of atmospheric extraction is (0.964 ± 0.001 stat ± 0.024 sys ) Bq/kg atmAr , which is consistent with results from other experiments. A cross-check analysis using different event selection criteria and a different statistical method confirms the result. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Caracterización de parámetros de calidad seminal en variedades amenazadas de la raza porcina Ibérico.

Author

Díaz-Ruíz, E., González-Ariza, A., León, J. M., Peláez-Caro, M., Venegas, M., Forero, F. J., Salgado, J., Pérez-Marín, C. C., Navas-González, F. J., Delgado, J. V., Galán-Luque, I., and Arando, A.

Subjects
REFERENCE values, SEMEN, SPERMATOZOA, BOARS, SWINE, MORPHOLOGY, REPRODUCTIVE technology, SPERM banks
Abstract

Copyright of Archivos de Zootecnia is the property of Archivos de Zootecnia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

46. Cuando los sujetos se mueven de su lugar: Una interrogación al extractivismo y la movilidad en la ecología política [When subjects move out of place: Questioning extractivism and mobility within Latin American political ecology]

Author

Bayón Jimenez, M., Teijlingen, K.M. van, Álvarez Velasco, S., and Moreano Venegas, M.

Subjects
Anthropology and Development Studies
Abstract

Contains fulltext : 240978.pdf (Publisher’s version ) (Open Access) Como en toda América Latina, la ecología política ha surgido como uno de los abordajes principales dentro del debate sobre los extractivismos en Ecuador. Desde nuestra contribución activa a este debate, nuestro objetivo con este artículo es reflexionar sobre los aportes y limitaciones que ha supuesto la ecología política latinoamericana para el análisis del extractivismo, y en particular las posiciones de los sujetos comunitarios e indígenas. Analizaremos el enfoque analítico que se da a escenarios de conflicto, y cómo este tiende a asignar a dichos sujetos un lugar fijo tanto geográfico como de enunciación. Esto pueda representar un limitante, particularmente en casos donde la construcción del espacio, la naturaleza, y las posiciones de los sujetos se atraviesa por historias y prácticas de movilidad. Con base en tres estudios de casos de despojo extractivo-capitalista en la Amazonía Ecuatoriana, mostramos que al establecer un diálogo entre la ecología política y la geografía crítica de las movilidades se puede enriquecer el enfoque analítico sobre el extractivismo y las posiciones de los sujetos. 25 p.

Published
2021

47. P1275: PERCENTAGE OF TUMOR INFILTRATING T LYMPHOCYTES MEASURED BY FLOW CYTOMETRY AT DIAGNOSIS PREDICTS SURVIVAL AFTER SALVAGE CHEMOTHERAPY IN RELAPSED/ REFRACTORY DIFFUSE LARGE B CELL LYMPHOMA PATIENTS.

Author

Korin, L., primary, Fuente, M., additional, Cranco, S., additional, Vitriu, A., additional, Ochoa, P., additional, Babuin, E., additional, Gelo, O., additional, Ayala, L., additional, Tempra, P., additional, Venegas, M., additional, Novoa, A., additional, Vijnovich, A., additional, Tartas, N., additional, Custidiano, M. D. R., additional, Foncuberta, M. C., additional, and Sanchez Avalos, J., additional

Published
2022
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49. An Acceptability Study Of A Personal Portable Device Storing Critical Health Information To Ensure Treatment Continuity Of Home-Dwelling Older Adults In Case Of A Disaster

Author

Hein Willius A, Torres Hidalgo M, Arroyo Zuñiga P, Quezada Venegas M, Arriagada Díaz C, Valenzuela Abarca E, San Martín Gutierrez E, and Bedregal P

Subjects
lcsh:R5-920, portable electronic health records technology acceptability older adults, wearable health devices, lcsh:Medicine (General)
Abstract

Andreas Hein Willius,1 Marisa Torres Hidalgo,2 Pablo Arroyo Zuñiga,1 Margarita Quezada Venegas,1 Christian Arriagada Díaz,3 Eduardo Valenzuela Abarca,4 Ernesto San Martín Gutierrez,5 Paula Bedregal6 1Project DEPPAS-FONDEF (ID17AM0038), Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Región Metropolitana, Chile; 2Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Región Metropolitana, Chile; 3School of Social Work, Faculty of Psychology, Universidad San Sebastián, Santiago, Chile; 4Department of Internal Medicine, Geriatric Program, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Región Metropolitana, Chile; 5Interdisciplinary Laboratory for Social Statistics, Faculty of Mathematics, Pontifical Catholic University of Chile, Santiago, Región Metropolitana, Chile; 6Department of Public Health, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Región Metropolitana, ChileCorrespondence: Andreas Hein WilliusDepartamento de Salud Pública, Escuela de Medicina, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, Santiago, Región Metropolitana, Segundo Piso, ChileTel +569 5624 0699Email aahein@uc.clAims: DEPPAS (“Dispositivo Electrónico Personal y Portable en Salud” or Personal, Portable Electronic Health Device in English) is a portable device in form of a bracelet that allows storing electronic health records of older adults experiencing chronic illnesses. The device seeks to support the vital sustainability of older adults by storing critical health information when electronic or paper records have been lost as a consequence of a disaster. Older adults are particularly vulnerable to experience negative consequences in this context. The present study explores the end-user acceptability of DEPPAS in order to inform the next design stages of the device.Methods: Twenty home-dwelling urban male and female older adults enrolled in a chronic health management program were invited to participate in two focus groups. A prototype of DEPPAS was presented and reactions to health service disruption scenarios were explored. Focus groups were transcribed. Content analysis based on the Technology Acceptance Model was conducted.Results: Older adults are acutely aware of their vulnerable health status. Participants report overall positive reactions to DEPPAS. The device was associated with feelings of relief and an increased sense of control over their health management. DEPPAS is perceived as useful, usable, and safe. Even though concerns regarding confidentiality were raised, benefits are perceived as more relevant than potential risks. Participants agree that its usefulness could be extended beyond disaster situations to everyday health care management. Implications for future development and limitations are discussed.Conclusion: The conceptual design DEPPAS shows a high level of acceptability by this end user and a high potential to be integrated with other complementary technologies (e.g. GPS, medication reminders) that could significantly contribute to improving health management in disaster situations.Keywords: wearable health devices, portable electronic health records, acceptability, older adults

Published
2019

50. Tuberculosis and COVID-19 co-infection: description of the global cohort

Author

Migliori, G. B., Casco, N., Jorge, A. L., Palmero, D. J., Alffenaar, J. -W., Denholm, J., Fox, G. J., Ezz, W., Cho, J. -G., Skrahina, A., Solodovnikova, V., Bachez, P., Piubello, A., Arbex, M. A., Alves, T., Rabahi, M. F., Pereira, G. R., Sales, R., Silva, D. R., Saffie, M. M., Miranda, R. C., Cancino, V., Carbonell, M., Cisterna, C., Concha, C., Cruz, A., Salinas, N. E., Revillot, M. E., Valdes, J. F., Fernandez, I., Flores, X., Tapia, P. G., Garavagno, A., Vera, C. G., Bahamondes, M. H., Merino, L. M., Munoz, E., Munoz, C., Navarro, I., Subiabre, J. N., Ortega, C., Palma, S., Pradenas, A. M., Pereira, G., Castillo, P. P., Pinto, M., Pizarro, R., Bidegain, F. R., Rodriguez, P., Sanchez, C., Salinas, A. S., Soto, A., Taiba, C., Venegas, M., Riquelme, M. S. V., Vilca, E., Villalon, C., Yucra, E., Li, Y., Guelvez, B., Plaza, R. V., Hoyos, K. Y. T., Andrejak, C., Blanc, F. -X., Dourmane, S., Froissart, A., Izadifar, A., Riviere, F., Schlemmer, F., Manika, K., Diallo, B. D., Hassane-Harouna, S., Artiles, N., Mejia, L. A., Gupta, N., Ish, P., Mishra, G., Sharma, S., Singla, R., Udwadia, Z. F., Alladio, F., Angeli, F., Calcagno, A., Centis, R., Codecasa, L. R., D'Ambrosio, L., De Lauretis, A., Esposito, S., Formenti, B., Gaviraghi, A., Giacomet, V., Goletti, D., Gualano, G., Matteelli, A., Motta, I., Palmieri, F., Pontali, E., Prestileo, T., Riccardi, N., Saderi, L., Saporiti, M., Sotgiu, G., Stochino, C., Tadolini, M., Torre, A., Villa, S., Visca, D., Danila, E., Diktanas, S., Ridaura, R. L., Lopez, F. L. L., Torrico, M. M., Rendon, A., Akkerman, O. W., Souleymane, M. B., Al-Abri, S., Alyaquobi, F., Althohli, K., Aizpurua, E., Gonzales, R., Jurado, J., Loban, A., Aguirre, S., Teixeira, R. C., De Egea, V., Irala, S., Medina, A., Sequera, G., Sosa, N., Vazquez, F., Llanos-Tejada, F. K., Manga, S., Villanueva-Villegas, R., Araujo, D., Duarte, R., Marques, T. S., Grecu, V. I., Socaci, A., Barkanova, O., Bogorodskaya, M., Borisov, S., Mariandyshev, A., Kaluzhenina, A., Vukicevic, T. A., Stosic, M., Beh, D., Ng, D., Ong, C. W. M., Solovic, I., Dheda, K., Gina, P., Caminero, J. A., Cardoso-Landivar, J., De Souza Galvao, M. L., Dominguez-Castellano, A., Garcia-Garcia, J. -M., Pinargote, I. M., Fernandez, S. Q., Sanchez-Montalva, A., Huguet, E. T., Murguiondo, M. Z., Bart, P. -A., Mazza-Stalder, J., Bakko, F., Barnacle, J., Brown, A., Chandran, S., Killington, K., Man, K., Papineni, P., Tiberi, S., Utjesanovic, N., Zenner, D., Hearn, J. L., Heysell, S., and Young, L.

Subjects
Pulmonary and Respiratory Medicine, Cohort Studies, Male, Coinfection, Humans, Prospective Studies, COVID-19, Tuberculosis, Original Research Article
Abstract

BackgroundInformation on tuberculosis (TB) and coronavirus disease 2019 (COVID-19) is still limited. The aim of this study was to describe the features of the TB/COVID-19 co-infected individuals from a prospective, anonymised, multicountry register-based cohort with special focus on the determinants of mortality and other outcomes.MethodsWe enrolled all patients of any age with either active TB or previous TB and COVID-19. 172 centres from 34 countries provided individual data on 767 TB-COVID-19 co-infected patients, (>50% population-based).ResultsOf 767 patients, 553 (74.0%) out of 747 had TB before COVID-19 (including 234 out of 747 with previous TB), 71 (9.5%) out of 747 had COVID-19 first and 123 (16.5%) out of 747 had both diseases diagnosed within the same week (n=35 (4.6%) on the same day). 85 (11.08%) out of 767 patients died (41 (14.2%) out of 289 in Europe and 44 (9.2%) out of 478 outside Europe; p=0.03): 42 (49.4%) from COVID-19, 31 (36.5%) from COVID-19 and TB, one (1.2%) from TB and 11 from other causes. In the univariate analysis on mortality the following variables reached statistical significance: age, male gender, having more than one comorbidity, diabetes mellitus, cardiovascular disease, chronic respiratory disease, chronic renal disease, presence of key symptoms, invasive ventilation and hospitalisation due to COVID-19. The final multivariable logistic regression model included age, male gender and invasive ventilation as independent contributors to mortality.ConclusionThe data suggest that TB and COVID-19 are a “cursed duet” and need immediate attention. TB should be considered a risk factor for severe COVID disease and patients with TB should be prioritised for COVID-19 preventative efforts, including vaccination.

Published
2021

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