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Your search keyword '"Ven, M.T.P. van de"' showing total 18 results
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18 results on '"Ven, M.T.P. van de"'

1. Radiolabeled interleukin-8: specific scintigraphic detection of infection within a few hours

Author

Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Ven, M.T.P. van de, Meer, J.W.M. van der, and Corstens, F.H.M.

Subjects
Fever of unknown origin, Febris e causa ignota, Development of radiopharmaceuticals for diagnosis and therapy of pathological processes, Ontwikkeling van radiofarmaca ten behoeve van diagnose en behandeling van ziekteprocessen
Abstract

Item does not contain fulltext

Published
2000

2. Experimentally induced inflammatory conditions

Author

Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Laverman, P., Ven, M.T.P. van de, Corstens, F.H.M., and Meer, J.W.M. van der

Subjects
Scintigrafische detectie van ontstekingen met radioaktief gelabelde cytokinen, Scintigraphic detection of inflammation with radiolabeled cytokines
Abstract

Item does not contain fulltext

Published
1998

3. Technetium-99m-labeled chemotactic peptides in acute infection and inflammation

Author

Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Ven, M.T.P. van de, Edwards, D.S., Barrett, J.A., Meer, J.W.M. van der, and Corstens, F.H.M.

Subjects
Scintigrafische detectie van ontstekingen met radioaktief gelabelde cytokinen, Fever of unknown origin, Febris e causa ignota, Scintigraphic detection of inflammation with radiolabeled cytokines
Abstract

Item does not contain fulltext

Published
1997

4. Cerebrovascular response to acute metabolic acidosis in humans

Author

Ven, M.T.P. van de, Colier, W.N.J.M., Kersten, B.T.P., Oeseburg, B., and Folgering, H.T.M.

Subjects
Effective Hospital Care [EBP 2], Vascular medicine and diabetes [UMCN 2.2], Heart, lung and circulation [UMCN 2.1]
Abstract

Item does not contain fulltext OBJECTIVES: Evaluation of the cerebrovascular response (delta CBV/delta PaCO2) during baseline metabolic conditions and acute metabolic acidosis. METHODS: 15 healthy subjects, 5 m, 10 f, 56 +/- 10 yrs were investigated. For acidification, NH4Cl was given orally. CBV was measured using Near Infrared Spectroscopy (OXYMON) during normo-, hyper- and hypocapnia. RESULTS: Acute metabolic acidosis was realised: mean delta BE -2.7 mEq.L-1 (p < 0.001) with mean delta PaCO2 -0.2 kPa (p < 0.01). During normo-, hyper- and hypocapnia, CBV values of 3.51, 4.82 and 2.55 mL.100 g-1 were calculated during baseline metabolic conditions and 3.70, 4.86 and 2.63 mL.100 g-1 during acute metabolic acidosis. The CBV/PaCO2 response showed a hockeystick configuration with the point of infliction around normocapnia. delta CBV/delta PaCO2 reactivity from normo- to hypercapnia and from normo- to hypocapnia was calculated; no significant differences in delta CBV/delta PaCO2 were found in both metabolic conditions. CONCLUSION: Cerebrovascular reactivity to CO2 does not alter during acute metabolic acidosis.

Published
2003

7. Dosimetry and risk estimates of radioiodine therapy for large, multinodular goiters

Author

Huysmans, D.A.K.C., Buijs, W.C.A.M., Ven, M.T.P. van de, Kloppenborg, P.W.C., Broek, W.J.M. van den, Hermus, A.R.M.M., and Corstens, F.H.M.

Subjects
Diagnostic Imaging, Development of radiopharmaceuticals for diagnosis and therapy of pathological processes, Radioiodine treatment of patients with nodular goiter, Infection, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), Behandeling met radioactief jodium bij patienten met een nodulaire struma, Ontwikkeling van radiofarmaca ten behoeve van diagnose en behandeling van ziekteprocessen
Abstract

Contains fulltext : 23737___.PDF (Publisher’s version ) (Open Access)

Published
1996

9. Ventilatory response in metabolic acidosis and cerebral blood volume in humans.

Author

Ven, M.T.P. van de, Colier, W.N.J.M., Sluijs, M.C. van der, Oeseburg, B., Folgering, H.T.M., Ven, M.T.P. van de, Colier, W.N.J.M., Sluijs, M.C. van der, Oeseburg, B., and Folgering, H.T.M.

Abstract

Item does not contain fulltext, The relationship between alterations in cerebral blood volume (CBV) and central chemosensitivity regulation was studied under neutral metabolic conditions and during metabolic acidosis. Fifteen healthy subjects (5610 years) were investigated. To induce metabolic acidosis, ammonium chloride (NH(4)Cl) was given orally. CBV was measured using Near Infrared Spectroscopy during normo- and hypercapnia and related to inspired ventilation (V(i)). A mean acute metabolic acidosis of Delta pH - 0.04 was realized with a mean decreased arterialized capillary PCO(2) (P(c)CO(2)) of 0.20 kPa (1.5 mmHg) (both P<0.001). During normocapnia, CBV was 3.510.71 and 3.650.56 ml 100 g(-1) (meanS.D.), measured under neutral metabolic conditions and during acute metabolic acidosis, respectively (ns). Corresponding values of V(i) were 7.61.4 and 10.02.4 l min(-1) (P<0.01), respectively. The slopes of the CO(2)-responsiveness (DeltaCBV/DeltaP(c)CO(2) and DeltaV(i)/DeltaP(c)CO(2)), were not significantly different during both metabolic conditions. A significant correlation between DeltaCBV/DeltaP(c)CO(2) and DeltaV(i)/DeltaP(c)CO(2) was found during metabolic acidosis (P<0.01), but not under neutral metabolic conditions. CBV does not contribute in a predictable way to the regulation of central chemoreceptors.

Published
2001

10. Can cerebral blood volume be measured reproducibly with an improved near infrared spectroscopy system?

Author

Ven, M.T.P. van de, Colier, W.N.J.M., Sluijs, M.C. van der, Walraven, D., Oeseburg, B., Folgering, H.T.M., Ven, M.T.P. van de, Colier, W.N.J.M., Sluijs, M.C. van der, Walraven, D., Oeseburg, B., and Folgering, H.T.M.

Abstract

Item does not contain fulltext, In some circumstances, cerebral blood volume (CBV) can be used as a measure for cerebral blood flow. A new near infrared spectroscope was used for determining the reproducibility of CBV measurements assessed by the O2-method. Twenty-seven healthy subjects were investigated. An intrasubject coefficient of variation (CV) was calculated, based on four identical episodes of desaturation-resaturation (O2-method) procedures for CBV measurements. Two trials were performed, with (trial 1) and without (trial 2) disconnecting the equipment. A mean CV of 12.6% and 10.0% was found in trial 1 and 2, respectively. Cerebral blood volume values yield 3.600.82 mL 100 g(-1). Cerebral blood volume could be measured reproducible in adults using near infrared spectroscopy, if the arterial desaturation is limited to approximately 5% from baseline level.

Published
2001

11. Ventilatory and cerebrovascular responses in normocapnic and hypercapnic COPD patients.

Author

Ven, M.T.P. van de, Colier, W.N.J.M., Sluijs, M.C. van der, Kersten, B.T.P., Oeseburg, B., Folgering, H.T.M., Ven, M.T.P. van de, Colier, W.N.J.M., Sluijs, M.C. van der, Kersten, B.T.P., Oeseburg, B., and Folgering, H.T.M.

Abstract

Item does not contain fulltext, This study investigated the hypothesis that hypercapnia in some chronic obstructive pulmonary disease (COPD) patients may be related to a high cerebrovascular response to carbon dioxide (CO2). The relationship between responses of ventilation and of cerebral blood volume (CBV) to acute changes in carbon dioxide tension in arterial blood (Pa,CO2) was measured in 17 chronic hypercapnic (Pa,CO2 >6.0 kPa) and 16 normocapnic (Pa,CO2 < or = 6.0 kPa) COPD patients, who were matched for degree of airway obstruction (forced expiratory volume in one second 27% predicted). Results were compared with 15 age-matched healthy subjects. CBV was measured using near infrared spectroscopy during normo- and hypercapnia and related to inspired minute ventilation (V'I) and mouth occlusion pressure (P0.1). Hypercapnia (end-tidal pressure of carbon dioxide (deltaPET,CO2) > 1 kPa) was induced by giving adequate amounts of CO2 in the inspired air. During normocapnia, CBV (mL x 100 g(-1)) was 2.41 0.66 and 2.90 0.60 (mean SD) in the normocapnic and chronic hypercapnic patients, respectively, which was significantly lower compared to healthy subjects (3.53 0.77). All slopes of CO2 responsiveness (deltaCBV/deltaPa,CO2, deltaV'I/deltaPa,CO2, deltaP0.1/deltaPa,CO2) were significantly lower in both COPD groups relative to healthy subjects, but were not significantly different between the COPD groups. A poor but positive correlation between ventilatory and cerebrovascular CO2 responsiveness (deltaCBV/deltaPa,CO2 and deltaV'I/deltaPa,CO2) was found in COPD patients and healthy subjects. The findings do not support the hypothesis of abnormal cerebrovascular responses to carbon dioxide in hypercapnic chronic obstructive pulmonary disease patients.

Published
2001

12. Radiolabelled interleukin-1 receptor antagonist for detection of synovitis in patients with rheumatoid arthritis

Author

Barrera Rico, P., Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Ven, M.T.P. van de, Lent, P.L.E.M. van, Putte, L.B.A. van de, Corstens, F.H.M., Barrera Rico, P., Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Ven, M.T.P. van de, Lent, P.L.E.M. van, Putte, L.B.A. van de, and Corstens, F.H.M.

Abstract

Contains fulltext : 140199.pdf (publisher's version ) (Closed access)

Published
2000

16. Preferential localization of systemically administered radiolabeled interleukin 1alpha in experimental inflammation in mice by binding to the type II receptor

Author

Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Ven, M.T.P. van de, Chizzonite, R., Corstens, F.H.M., Meer, J.W.M. van der, Laken, C.J. van der, Boerman, O.C., Oyen, W.J.G., Ven, M.T.P. van de, Chizzonite, R., Corstens, F.H.M., and Meer, J.W.M. van der

Abstract

Contains fulltext : 24689___.PDF (publisher's version ) (Open Access)

Published
1997

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