852 results on '"Velkov, Tony"'
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2. Metabolic profiling unveils enhanced antibacterial synergy of polymyxin B and teixobactin against multi-drug resistant Acinetobacter baumannii
3. Synergistic potential of Leu10-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus
4. Differential MRGPRX2-dependent activation of human mast cells by polymyxins and octapeptins
5. Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii
6. The role of HnrnpF/H as a driver of oligoteratozoospermia
7. Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress
8. Phage resistance in Klebsiella pneumoniae and bidirectional effects impacting antibiotic susceptibility
9. Transcriptomic Mapping of Neurotoxicity Pathways in the Rat Brain in Response to Intraventricular Polymyxin B
10. Model-informed dose optimisation of polymyxin-rifampicin combination therapy against multidrug-resistant Acinetobacter baumannii
11. Advancing Nitrile‐Aminothiol Strategy for Dual and Sequential Bioconjugation
12. T-2 toxin and its cardiotoxicity: New insights on the molecular mechanisms and therapeutic implications
13. Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa
14. A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens
15. Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway
16. Synergistic potential of Leu10-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus.
17. Exploring Structure–Activity Relationships and Modes of Action of Laterocidine.
18. Untargeted metabolomics to evaluate polymyxin B toxicodynamics following direct intracerebroventricular administration into the rat brain
19. Unique mechanistic insights into pathways associated with the synergistic activity of polymyxin B and caspofungin against multidrug-resistant Klebsiella pneumoniae
20. Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination
21. Identification of Potential Targets Mediating Polymyxin Toxicity in Human Alveolar Epithelial Cells
22. Providing insight into the mechanism of action of cationic lipidated oligomers using metabolomics
23. Novel Antimicrobial Peptides: Targeting Wound Infections Caused by ‘Superbugs’ Resistant to All Current Antibiotics
24. Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity
25. Molecular mechanisms of aflatoxin neurotoxicity and potential neuroprotective agents
26. Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane
27. Colistin Induces Oxidative Stress and Apoptotic Cell Death through the Activation of the AhR/CYP1A1 Pathway in PC12 Cells.
28. Fe3O4‐Incorporated Metal‐Organic Framework for Chemo/Ferroptosis Synergistic Anti‐Tumor via the Enhanced Chemodynamic Therapy.
29. History, Chemistry and Antibacterial Spectrum
30. Mechanisms of Polymyxin-Induced Nephrotoxicity
31. Polymyxins: Mode of Action
32. Discovery of Novel Polymyxin-Like Antibiotics
33. Complete genome sequence and genome-scale metabolic modelling of Acinetobacter baumannii type strain ATCC 19606
34. Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens
35. Providing insight into the mechanism of action of Cationic Lipidated Oligomers (CLOs) using metabolomics
36. Transcriptomic interplay betweenAcinetobacter baumannii, human macrophage and polymyxin
37. High-level nitrofurantoin resistance in a clinical isolate of Klebsiella pneumoniae: a comparative genomics and metabolomics analysis
38. Structure–Interaction Relationship of Polymyxins with Lung Surfactant
39. Integrated Transcriptomic and Metabolomic Mapping Reveals the Mechanism of Action of Ceftazidime/Avibactam against Pan-Drug-Resistant Klebsiella pneumoniae
40. The antihelminth drug rafoxanide reverses chromosomal-mediated colistin-resistance in Klebsiella pneumoniae
41. Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria
42. T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway
43. The inhibitory effects of eighteen front-line antibiotics on the substrate uptake mediated by human Organic anion/cation transporters, Organic anion transporting polypeptides and Oligopeptide transporters in in vitro models
44. Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens
45. Polymyxins and Analogues Bind to Ribosomal RNA and Interfere with Eukaryotic Translation in Vitro
46. T-2 toxin neurotoxicity: role of oxidative stress and mitochondrial dysfunction
47. Bifunctional antibiotic hybrids: A review of clinical candidates
48. A traceless reversible polymeric colistin prodrug to combat multidrug-resistant (MDR) gram-negative bacteria
49. High-level nitrofurantoin resistance in a clinical isolate of Klebsiella pneumoniae: a comparative genomics and metabolomics analysis.
50. Global Metabolic Analyses of Acinetobacter baumannii
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