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Purpose: To evaluate the nutritional status (NS) of patients planned for maxillectomy and prosthodontic rehabilitation using three nutritional assessment methods. Methods: This longitudinal study enrolled 18 planned maxillectomy patients following the inclusion and exclusion criteria. NS was evaluated at five stages: before surgery (S0), 2 weeks after surgery (S1), 3 months after insertion of intermediate obturator (S2), just before fabrication of definitive obturator (S3), and 3 months after insertion of definitive obturator (S4) using two nutritional assessment tools i.e. Patient Generated -Subjective Global Assessment (PG-SGA) &Nutritional risk index (NRI); and body composition indicators i.e. body mass index (BMI), fat free mass (FFM), total body water (TBW), skeletal muscle mass (SMM) and skeletal muscle mass index (SMMI).To determine the changes in patient's nutritional status among different time points Repeated Measure ANOVA with Bonferroni post hoc adjustments was used. Results: Out of 18 patients, 12 were completed the study. NS of maxillectomy patients deteriorates significantly (p .05) except for PG-SGA (p

Purpose: To compare stress distribution in polyacetyl based flexible RPD (FRPD) with cast metal RPD (CRPD) by using three-dimensional finite element analysis (FEA) and patient satisfaction by using OHIP-14 questionnaire in participants with Kennedy's class I partially edentulous mandibular arch rehabilitated with CRPD and FRPD. Material and methods: For FEA, 3D models of Kennedy's class I partially edentulous mandibular arch, CRPD in chrome-cobolt alloy, and polyacetyl based FRPD were geometrically modelled and subjected to a vertical load of 100 ​N bilaterally. The in vivo comparison of satisfaction was assessed by enrolling 22 participants with Kennedy's class I partially edentulous mandibular arch. After randomization, 11 participants were rehabilitated by CRPD (group C), and 11 participants by polyacetyl based FRPD (group F). OHIP-14 questionnaire in Hindi language was filled at 1 week and 1 year after denture insertion. Results: Von Mises stress distribution in CRPD was maximum in mesial rest seat of the primary abutment (100 ​MPa) and minimum for edentulous ridge (7 ​MPa on bone and 6 ​MPa on mucosa). Von Mises stress distribution for polyaccetyl based FRPD was maximum in ridge (25 ​MPa) and minimum in periodontal ligament of the second premolar (3 ​MPa). Patient satisfaction in group F was significantly more than in group C at end of 1 year (P ​= ​.0158). Conclusion: FRPD is useful in periodontally compromised abutment teeth and CRPD in resorbed ridge conditions. Patient satisfaction is more with polyacetyl based flexible RPD when compared with cast metal RPD at the end of 1 year.

Purpose: To compare ridge resorption (RR) and patient satisfaction in single implant-supported mandibular overdentures (SIMO) with conventional complete dentures (CCD) over a period of one year. Material and methods: This prospective, randomized trial enrolled 30 completely edentulous participants following inclusion and exclusion criteria. The study was completed by 28 participants. Rehabilitation of 14 participants was done by using SIMO (group I) and CCD (group C) each according to randomization chart. For both the groups, RR was computed in millimeters from residual ridge height measured by using orthopantogram at 6 months (T1), 9 months (T2), and 12 months (T3) at 3 anatomic locations: maxillary posterior (L1), maxillary anterior (L2), and mandibular posterior (L3). Patient satisfaction was evaluated by using Geriatric Oral Health Assessment Index Hindi version (GOHAI-Hi) at 1week and 12 months after denture delivery. Results: At 12 months, minimum RR was observed at L2 of group I (0.62 ​± ​0.20 ​mm) and maximum RR was observed at L3 of group C (1.04 ​± ​0.15 ​mm). Comparison of ridge resorption between group I and group C was statistically significant at T3 (P ​= ​.001 for L1, P ​= ​.006 for L2, and P ​= ​.028 for L3). At T3, in group I, RR was more at L3 than L2 region (P ​= ​.011) and L1 region (P ​= ​.015). Statistically significant difference of GOHAI-Hi scores was observed between group I and group C at end of 12 months (P ​= ​.003). Conclusions: SIMO cause less RR and higher patient satisfaction as compared to CCD and can be recommended with higher predictability of success than CCD.

Purpose: To discuss the indications, technical steps for fabrication of implant retained auricular prosthesis (IRAP), and treatment outcome at various follow up visits. Materials and methods: We performed retrospective data collection of all consecutively treated patients referred to us for auricular reconstruction from 2006 till 2018. Each case was analysed for: feasibility of autogenous reconstruction vs IRAP, surgical procedure, type of anaesthesia, type of implants, soft tissue response, implant success and survival rate, prosthetic attachment, aesthetic outcome, complications and patient acceptance. Procedure for fabrication of IRAP has also been written in detail to benefit readers. Results: IRAP was considered feasible and performed in eight out of 27 patients referred for auricular reconstruction. 20 implants were placed and total 10 prostheses were fabricated. Implant success rate and survival rate was 90% and 100% respectively till last follow-up of each patient. Bar and clip attachments were used in 60% and stud attachments in 40% of prostheses. After stage II surgery, grade I soft tissue inflammation was reported around two implants (10%), and grade III around one implant (5%). Implant with grade III inflammation showed features of recurrent infection and thus was left buried under soft tissues. These prostheses were aesthetically pleasing in all cases in the early post-operative period. Conclusions: A systematic, step wise procedure with multi-disciplinary approach is a key to success for the fabrication of implant retained auricular prosthesis.

Aim: The objective is to evaluate the effect of intravenous (i.v.) administration of bisphosphonate (zoledronic acid) therapy on the jaw bone density and incidence of any other bony patholog. Settings and Design: Observational – prospective study. Materials and Methods: A total of 57 patients having a history of bony metastasis (excluding the jaw bone) were enrolled following the inclusion/exclusion criteria. Each patient received six doses of 4 mg i.v. bisphosphonate once a month. Multidetector computed tomography (MDCT) of jawbones for each patient was performed before the start of therapy (baseline) and subsequently at 6 and 12 months. Bone density was assessed at 24 predetermined sites (8 sites in maxilla and 16 sites in mandible) and any pathological change in either of the jaw bones was noted. Statistical Analysis Used: Shapiro–Wilk test ,Pearson's Chisquare test and repeated measures analysis of variance. Results: The result showed no statistically significant increase in mean bone density over a period of 1 year in maxilla and mandible. However, a significant increase in bone density was observed from 6 months to 1 year in mandibular anterior cancellous bone. The detailed observation of each MDCT scan showed no pathological change in either of the jaw bones during the study period. Conclusion: The administration (i.v.) of six doses of 4 mg bisphosphonate did not lead to a significant change in bone density over a period of 1 year.

Guava (Psidium guajava L.) is an important fruit cultivated in tropical and sub-tropical countries. Being a climacteric fruit it has very high respiration and deterioration rates (shelf-life 3-4 days), making a challenge for storage. Therefore, the present experiment was conducted during 2016–17 to reduce the post-harvest losses and extension of shelf-life of guava fruits var. Hisar Surkha using the combination of selenium and chitosan treatments. The mature green freshly harvested guava fruits were treated with selenium solutions (0.01 ppm, 0.02 ppm, and 0.05 ppm) in combination with 1.5% chitosan containing 0.5% acetic acid for 5 min and stored at room temperature (20±2°C, 82±5% RH). The fruits were analyzed for physico-chemical attributes (physiological weight loss, fruit firmness, total soluble solids, and titratable acidity) and biochemical characteristics (total phenolic, flavonoid contents, and total antioxidant activity) at three days interval. The combined treatments of selenium and chitosan helped in delaying weight loss (9.66%), lower disease incidence, better retention of fruit firmness (4.70 kg/cm2), soluble solids (13.03 ºBrix), titratable acidity (0.38%) compared to control on 12th day of storage. Treatment of guava fruits with selenium and chitosan also maintained higher total phenols (24.99 mg GAE /g dry wt.), flavonoids (3.51 mg CE/g dry wt.) and exhibited higher antioxidant activity (54.32%) throughout storage. The present study showed that combination of Se (0.02 ppm) and chitosan (1.5%) was most effective in maintaining post-harvest quality and enhance the shelf life of guava fruits up to 12 days during storage at room temperature.

Background: Oral hygiene maintenance is crucial for prevention of various oral diseases. Oral hygiene practices across the country vary largely and people in peri-urban and rural areas use traditional methods of oral hygiene like powders, bark, oil and salt etc. Their effect on oral soft and hard tissues need to be studied to understand their beneficial and/ or harmful effects on maintenance of oral hygiene and prevention or causation of oral diseases. Objectives: This study aimed to assess the plaque-cleaning efficacy, gingival bleeding, recession and tooth wear with different traditional oral hygiene methods as compared to use of toothpaste-toothbrush, the most accepted method of oral hygiene practice. Study Design: Hospital based cross sectional analytical study. Results: Total 1062 traditional oral hygiene method users were compared with same number of toothpaste-brush users. The maximum number in the former group used tooth powder (76%) as compared to other indigenous methods, such as use of bark of trees etc and out of tooth powder users; almost 75% reported using red toothpowder. The plaque scores and gingival bleeding & recession were found to be more in traditional oral hygiene method users. The toothwear was also more severe among the toothpowder users. Conclusions: Traditional methods were found to be inferior in plaque control as was documented by increased bleeding and gingival recession. Its effect on hard tissues of teeth was very damaging with higher tooth wear scores on all surfaces.

Debridement of affected parts in patients with non-Hodgkin's lymphoma leads to large mid facial defects leading to poor quality of life due to cosmetic disfigurement and various functional comorbidities. Therefore, a surgeon should refer the patients to a prosthodontist for replacement of lost tissues to improve their function and esthetics. Two cases have been presented here with a history of non-Hodgkin's lymphoma having large, continuous defects involving nose, cheeks, and maxilla. Retaining large facial prosthesis and intraoral obturator was a challenge as supporting hard and soft tissues were less. Two-piece lightweight prostheses were fabricated and retained with the use of very economical titch buttons used (used in clothes) in case 1 due to financial constraints and slightly expensive iron boron neodymium magnets in case 2. Functional and esthetic rehabilitation was successfully achieved with intraoral and facial prostheses attached to each other.

Purpose: Soft liners act as a cushion between the denture base and the residual ridge. Hence, it is important to study their effect on resorption of mandibular denture bearing area. Therefore, the purpose of this study was to evaluate the influence of soft denture liner on mandibular ridge resorption after 1 year in completely denture wearers. Materials and Methods: Twenty-eight completely edentulous patients having age between 45 and 60 years with well-formed ridges in class I jaw relations were selected as per the inclusion and exclusion criterion. Randomization chart was used to enroll participants in experimental and control groups who were given mandibular dentures with and without soft denture liner, respectively. Vertical measurements were made on orthopantomograph and analyzed using Adobe Photoshop 7.0 software at five points, i.e., one at central incisor and two points at right and left first premolars and two in each first molar region. Results: On application of repeated measures analysis of variance, both groups showed a significant change in bone height after denture delivery (P < 0.05). Intergroup comparison (Wilcoxon rank sum test) of bone height in different regions at various time intervals showed statistically significant difference in bone levels (P < 0.05) from baseline to 6 months and baseline to 12months (P < 0.01), while the difference was statistically not significant during 6 and 12 months’ period. Conclusion: The use of soft denture liner significantly reduces the residual ridge resorption in complete denture wearers as compared to conventional denture wearers (without denture liner) over a period of 1 year.

Background Rates of smokeless tobacco(ST) use in India are very high and associated with grave health consequences. Research on effective ST cessation approaches is a priority. In a randomized double blind placebo controlled trial of varenicline for ST dependence in AIIMS, India, biochemically confirmed end-of-treatment(EOT) abstinence was greater for varenicline versus placebo(25.2% vs. 19.5%), but this was not statistically different(AOR = 1.6, 95% CI = 0.84-3.1, p = .15). Here, we studied the correlates of successful abstinence in this trial as such an evidence-base is crucial to optimize treatment strategies. Methods 237 ST users who were randomized to receive either varenicline(12 weeks, 1 mg, twice per day) or placebo were included in this analysis. Socio-demographics, ST use parameters (age of initiation, duration, chews per day, and FTND-ST scores), abstinence related parameters, baseline urinary cotinine levels, and treatment adherence were analyzed. Multivariate analysis, using biochemically confirmed point prevalence abstinence as the dependent variable, was done to predict the odds of quitting at EOT. Results Participants were predominantly males(97%) and mean age was 34.2(SD± 9)yrs. Using logistic regression on the whole group, baseline urinary cotinine and number of 24 hour quit attempts in the past significantly(p < 0.05) predicted cessation at EOT. The odds of abstinence increased with unit decrease in urinary cotinine levels(Exp(B) = 0.86) and unit increase in number of 24 hour quit attempts (Exp(B) = 0.66). In the varenicline arm average chews per day(Exp(B) = 0.91) and baseline depression scores using HAM-D also significantly predicted successful quitting. Greater adherence increased EOT cessation rates for varenicline (39% vs. 18%, p = .003) but not for placebo (28% vs. 14%, p = .06). Conclusions This has implications for optimizing treatment planning at a program level, especially in resource poor countries. Strategies to enhance treatment adherence and address depression would be important.

Aim: To evaluate and compare the effect of flapless and “open flap” techniques of implant placement on crestal bone height (CBH) around implants. Materials and Methods: This prospective study comprised of 32 implants placed in 16 subjects with a bilateral missing mandibular first molar. In each subject, one implant was placed with “flapless” and other using “open flap” technique. Radiographic assessment of CBH was carried out using standardized intraoral periapical radiograph of the site at baseline, 3 months, 9 months and 15 months after implant placement. Statistical Analysis: Data were analyzed using STATA 11.0 statistical software. To determine the changes in CBH from baseline, at 3-, 9-, and 15-month, repeated measures analysis of variance followed by post-hoc Bonferroni was used for each of the two techniques for mesial and distal aspects separately. For both techniques, changes in CBH from baseline to 15 months were compared using an independent t-test with a confidence interval of 95%. Results: For “flapless” technique, there was no statistically significant (P > 0.05) reduction of CBH in initial 9 months but was significant for the 9–15 months period while for “open flap” technique, statistically significant (P < 0.05) reduction was observed up to 15 months. Comparison of both techniques showed significantly lesser reduction with “flapless” than “open flap” technique. The overall average crestal bone loss was 0.046 ± 0.008 mm on mesial aspect, 0.043 ± 0.012 mm on distal aspect with “flapless” technique and 1.48 ± 0.085 mm on mesial aspect, 1.42 ± 0.077 on distal aspect “open flap” technique. Conclusions: Both techniques showed a reduction in CBH with time but the flapless technique showed a lesser reduction. Therefore, the flapless technique can be considered as a better treatment approach for placement of implants, especially where adequate width and height of available bone are present.

Statement of Problem: Change in color and loss of marginal adaptation of tooth colored restorative materials is not acceptable. Bleaching is commonly used for treating discolored teeth. However, the literature is scanty regarding its effect on color and marginal adaptation of direct and indirect composite laminate veneers (CLVs) under in vivo conditions. Purpose: Purpose of the study was to determine the effect of bleaching on color change and marginal adaptation of direct and indirect CLVs over a period of time when exposed to the oral environment. Materials and Methods: For this purpose, a total of 14 subjects irrespective of age and sex indicated for CLV restorations on maxillary anterior teeth were selected following the inclusion and exclusion criteria. For each subject, indirect CLVs were fabricated and looted in the first quadrant (Group 1) and direct CLV′s (Group 2), were given in the second quadrant. Color change was assessed clinically using intra-oral digital spectrophotometer and marginal adaptation was assessed on epoxy resin replica of the tooth-restoration interface under scanning electron microscope. After 6 months, the subjects underwent a home bleaching regimen for 14 days using 10% carbamide peroxide. The assessment of color change and marginal adaptation was done at 6 months after veneering (0-180 days), immediately after the bleaching regimen (0-194 days) and 3 months after the bleaching regimen (0-284 days). Results: The difference in median color change (ΔE) between the groups was tested using Wilcoxon rank sum test while the median color change with time within the groups was tested using Wilcoxon signed rank test. The difference in the rates of marginal adaptation was tested between the groups using Chi-square/Fisher′s exact test. Bleaching led to statistically significant color change at cervical (CE), middle and incisal (IE) regions when direct and indirect composites were compared (P < 0.05). During intra-group comparison, direct CLV′s showed significant color change at CE and IE regions when ΔE was compared at 180 days and 284 days (CE 10 vs. CE 30, P = 0.008, IE 10 vs. IE 30, P = 0.003). No significant differences were found when within group comparison was made for indirect laminates. Intergroup comparison between the groups showed significant difference in marginal adaptation at CE margin at all-time points (at baseline, P = 0.005; at 180 days, P = 0.007; 194 days, P = 0.025; at 284 days, P = 0.067). Conclusion: After bleaching, indirect CLVs performed better in terms of color stability whereas direct CLVs performed better in terms of marginal adaptation. Clinical Significance: Indirect composites should be preferred to direct composites as veneering materials as they have better color stability. Special attention should be given to their marginal adaptation especially in the CE region. Bleaching should be avoided in patients with composite restorations in the mouth.

Marginal mandibular resection to treat neoplasms leads to loss of alveolar bone and teeth at the affected side. Consequently patient suffers with poor masticatory performance and esthetic disfigurement, which we need to restore with the help of prosthodontic rehabilitation. The success of rehabilitation of these patients depends on strategic treatment planning and choice of most suitable treatment modality. In this article, case of a patient has been presented who underwent marginal mandibular resection and reported with many limiting factors like obliterated buccal and lingual sulci, attachment of lingual frenum and lower lip at the level of alveolar ridge and Macroglossia. Impression making and fabrication of a retentive prosthesis were the main challenges. Therefore, a modified impression technique was used to fabricate mandibular cast partial denture with extracoronal semi precision attachments to enhance the retention of the prosthesis.

Purpose: This preliminary hospital based study was designed to measure the mean maximum bite force (MMBF) in healthy Indian individuals. An attempt was made to correlate MMBF with body mass index (BMI) and some of the anthropometric features. Methodology: A total of 358 healthy subjects in the age range of 18-47 years (mean age = 26.66 ± 6.83) were selected following the selection criteria. Demographic details along with general physical and facial parameters such as height, weight, facial form, facial profile, arch form, and palatal contour were recorded in a predesigned proforma. The maximum bite force was recorded on both (right and left) sides using a specially designed piezoelectric transducer based device. Results: The MMBF in Indian individuals was found to be 372.39 ± 175.93 Newton (N). Males had significantly higher (P = 0.000) MMBF (448.47 ± 191.82 N) as compared to females (296.31 ± 116.79 N). Facial form (P = 0.001) and palatal contour (P = 0.000) showed a significant relationship with MMBF. Subjects having square facial form (421.34 ± 187.32 N) showed significantly higher MMBF as compared to other facial forms, that is, square tapered (358.86 ± 143.56 N; P = 0.038), ovoid (338.40 ± 163.02 N; P = 0.000) and tapered (349.22 ± 184.82 N; P = 0.028). Subjects with flat palatal contour showed significantly higher MMBF when compared to high (P = 0.002) and medium palatal (P = 0.002) contour. Though facial profile was not significantly related to MMBF, it was significantly higher in subjects having concave facial profile when compared to convex (P = 0.045) and straight (P = 0.039) facial profile. BMI and arch form showed no significant relationship with MMBF. Conclusion: The MMBF is found to be affected by gender and some of the anthropometric features like facial form and palatal contour.

Purpose: Decimated dentitions may require raising the vertical dimension in some conditions while performing a full mouth rehabilitation treatment. Increase in a vertical dimension should be diagnosed by reversible methods prior to performing any irreversible methods for a minimum time period. Reversible methods like splints and overlay dentures are often used for this purpose. These methods however cannot be used in some conditions like in cases of brittle teeth. Method: An alternative technique based on adhesive technology has been described which is reversible and yet minimally traumatic to teeth. Conclusions: The technique has two basic aims. The first is to accurately implement the occlusal scheme as planned in the diagnostic wax-up in the reversible method of altering the vertical dimension. The second aim is to increase the vertical dimension with minimal damage to the teeth.

Bisphosphonates are group of drugs that inhibit bone resorption and are used to treat a range of pathologies including Paget's disease, osteoporosis, multiple myeloma and metastasis associated with breast or prostate cancer. The most common complication in patients on bisphosphonate therapy is osteonecrosis of jaw (ONJ) which can occur after any surgical dental procedure and the risk for the development of osteonecrosis of jaw is higher in patients receiving intravenous bisphosphonate therapy than in patients receiving oral bisphosphonate therapy. Typical presentation is in the form of non-extraction socket, presence of exposed bone, gingival swelling or purulent discharge, when local debridement and antibiotics are ineffective.At present, there is no effective treatment for bisphosphonate induced osteonecrosis, so prevention is extremely important. Maximum precautions should be taken in patients who are at the risk of development of ONJ especially when any dental surgical procedure like extractions, retrograde apicoectomies, periodontal surgery and implant placement is contemplated. Dentists and oral or maxillofacial surgeon must keep up to date with the latest approaches or guidelines to prevention and the risk factors, particularly when treating patients who are on bisphosphonates, or who will be taking bisphosphonates.

Introduction: Osteopetrosis is a rare autosomal hereditary disorder characterized by abnormal functioning of osteoclasts, which leads to delayed wound healing. Hence chances of infection are increased even after minor surgical procedures. This paper aims to describe clinical features, and prosthodontic management of two patients who presented with clinical features of intermediate form of osteopetrosis and missing teeth. Case report: A 27-year-old patient having intermediate osteopetrosis presented with difficulty in chewing food and swallowing, due to edentulous maxillary and mandibular arches with large antral cavities, which developed secondary to tooth extraction. Another case discussed is a 25-year-old female patient who reported with chief complaints of difficulty in chewing due to resected left side of lower jaw. In these case reports, importance of avoiding extractions, preservation of remaining teeth and conservative management with minimum number of patients' visits has been emphasized. Conclusion: Efforts should be made to avoid dental extraction in such cases as chances of bone infection and fracture are more. If patient is partially or completely edentulous only removable type of prosthesis is advisable as bones are hypocalcified and maintenance of oral hygiene is easy with removable prosthesis.

Irrespective of the cause, abnormalities in shape, size, and position of body organs are often perceived as looking wrong. This perception can subject the individual to significant peer ridicule and social ostracism. Rehabilitation of patients with auricular defects can either be done by reconstructive surgery or by prosthetic means. The article draws a comparison between the implant-supported prosthesis and reconstructive surgery, listing the benefits, limitations, indications and contraindications of both the techniques. As both the available techniques give excellent results in appropriately selected situations, the restorative team must present all the alternatives to the patient and choose judiciously the better of the two.

Two ber varieties differing in their shelf lives (Umran, 8 to 9 and Illaichi, 4 to 5 days) were analyzed for cell wall components, cell wall degrading enzymes and their isoenzyme profile at immature green, mature green, turning colour, ripe and overripe stages of ripening. Cellulose and pectin contents decreased during ripening in both varieties. This decrease was accompanied by a corresponding increase in pectin methylesterase, polygalacturonase and cellulase. The increase in the activity of pectin methylesterase was about 20- and 10-fold, that of polygalacturonase about 8.4- and 5.7-fold, and of cellulase 5.5- and 4.4-fold in Umran and Illaichi, respectively. The basal level of activities of all these enzymes was higher at all the stages of ripening in Illaichi variety, having short shelf life, as compared to Umran, with long shelf life. This was further confirmed by the intensity of isoenzyme bands of these enzymes. The isoenzyme profile also revealed that two isoenzymes of each, pectin methylesterase and polygalacturonase, and one of cellulase could be considered as isoenzymes responsible for the softening of cell wall during ripening and could be potential targets for manipulation to delay softening during ripening.

Differences in the balance of shape, size, and position of body organs are immediately perceived as "looking wrong" and this perception can subject the individual to significant peer ridicule and social ostracism, often expressing as intense shame and anguish in the attitude of the afflicted. Rehabilitation of such patients can be remarkably beneficial on the individual′s self-esteem and body image. The onus of the deed lies in the hands of a team that combines artistic excellence with surgical expertise, by combining the skills of anaplastologists, surgeons, and prosthodontists. This is a review of a few surgical and prosthetic considerations in the management of auricular defect and a case description of management of a patient of microtia following similar guidelines in fabrication of the epithesis.

Background: To investigate the effect of restoration of lost vertical by centric stabilizing splint on electromyographic (EMG) activity of masseter and anterior temporalis muscles bilaterally in patients with generalized attrition of teeth. Materials and Methods: EMG activity of anterior temporalis and masseter muscle was recorded bilaterally for 10 patients whose vertical was restored with centric stabilizing splint. The recording was done at postural rest position and in maximum voluntary clenching for each subject before the start of treatment, immediately after placement of splint and at subsequent recall visits, with splint and without the splint. Results: The EMG activity at postural rest position (PRP) and maximum voluntary clench (MVC) decreased till 1 month for both the muscles. In the third month, an increase in muscle activity toward normalization was noted at PRP, both with and without splint. At MVC in the third month, the muscle activity without splint decreased significantly as compared to pretreatment values for anterior temporalis and masseter, while with the splint an increase was seen beyond the pretreatment values. Conclusion: A definite response of anterior temporalis and masseter muscle was observed over a period of 3 months. This is suggestive that the reversible increase in vertical prior to irreversible intervention must be carried out for a minimum of 3 months to achieve neuromuscular deprogramming. This allows the muscle to get adapted to the new postural position and attain stability in occlusion following splint therapy.

The present investigations were undertaken to ascertain the extent of lipid peroxidation, oxidative stress and antioxidative system during ripening of two varieties of ber fruits (Ziziphus mauritiana Lam.) differing in their shelf lives, viz. Umran (8–9 days) and Kaithali (4–5 days). Based on visual observations, fruits were categorized as immature green (IG), mature green (MG), turning colour (TC), ripe (R) and overripe (OR). Lipoxygenase (LOX) activity, malondialdehyde (MDA) value and H2O2 content increased significantly during ripening in both varieties, obtaining 3-, 3- and 2.5-fold increase in Umran and 4-, 3.5- and 3-fold increase in Kaithali, respectively. Kaithali being short-lived variety, exhibited higher values of these parameters at almost all the stages of fruit ripening. Activity of superoxide dismutase (SOD), glutathione reductase (GR) and ascorbate peroxidase (APX) increased during initial stages but thereafter decreased, whereas that of peroxidase (POX) decreased continuously during ripening. On the other hand, catalase (CAT) activity increased continuously as ripening progressed. In general, antioxidative enzymes exhibited comparatively higher activity in Umran. Total ascorbic acid content increased from IG to TC stage, while total glutathione increased up to MG stage and thereafter decreased in both varieties. Kaithali had higher content of ascorbate than Umran. β-Carotene and α-tocopherol also decreased as ripening progressed. However, the decrease was more pronounced in Umran as compared to Kaithali.

The dilemma confronting many dentists today is that innovations and well-defined specializations have greatly enlarged the treatment realm for tooth preservation as well as tooth replacement. The objectives should be preservation of the remaining tooth structure, restoration of optimum function, esthetics with least invasive procedures, cost effective, and short treatment time. The number of remaining natural teeth is one of the most widely used method for evaluating oral health and the prosthetic treatment of patients with a mutilated dentition. Though the treatment of these patients can be complex, but there are some important principles applicable in most cases. This case report demonstrates a satisfying full mouth rehabilitation using the Hobo and Takayama twin-stage procedure for a patient with esthetically and functionally compromised dentition. The final prosthesis with this twin-stage technique ensured a restoration with a predictable posterior disclusion and anterior guidance in harmony with the condylar path.

Long-term clinical failures of cemented prosthesis depend, to a large extent, on the integrity of the luting agent. The causative factors that lead to microfracture and, hence, failure of the luting agents are the stresses acting inside the oral cavity. Therefore, the present study was designed to develop an understanding of the relationship between stresses in the tooth and the failure potential of the luting agent. Two-dimensional finite element stress analysis was performed on the mandibular second premolar. The behavior of zinc-phosphate and glass-ionomer were studied under different crowns (metal-ceramic and metal crown) and loading conditions (mechanical force of 450 N acting vertically over the occlusal surface, thermal loads of 60° and 0°C). It was observed from the study that failure threshold of the luting agent was influenced both by the elastic modulus of the luting agent and by the type of the crown.

Introduction: Women presenting with unhealthy cervix needs to be evaluated with Papanicolaou (Pap) smear for epithelial abnormalities. Aim: To detect epithelial cell abnormalities in unhealthy cervix using the 2001Bethesda system of reporting for cervical cytology and to confirm histopathologicaly the findings of Pap smear. Materials and Methods: In this study, 125 women with clinical diagnosis of unhealthy cervix underwent conventional cytology. Cervical biopsies were taken from abnormal areas seen on colposcopy and sent for histopathology Results: Out of 125 Pap smears, 122 were satisfactory for evaluation (19 normal, 86 negative for intraepithelial lesion or malignancy and 17 with epithelial cell abnormality) and 3 were unsatisfactory (one hemorrhagic and two severe inflammation). Out of 17 (13.60%) cases with epithelial cell abnormality, ASCUS was seen in 6 (4.80%), LSIL in 7 (5.60%), HSIL in 1 (0.80%), squamous cell carcinoma in 1 (0.80%), AGC endocervical in 1 (0.80%) and adenocarcinoma in 1 (0.80%) patients. Cervical biopsy was taken in 67 women. Diagnostic accuracy of Pap smear for preinvasive and invasive disease was 81.15% with overall sensitivity and specificity 78.57% and 88.67% respectively and predictive value of 64.71%. Conclusion: Women with clinical diagnosis of unhealthy cervix should be evaluated by cytology to detect any premalignant or malignant lesions. The Bethesda system for cervical cytology reporting should be used universally as it will give a standardized interpretation.

This study was conducted to determine the effect of 15% carbamide peroxide bleaching agent on color change and surface topography of different composite veneering materials (Filtek Z350 (3M ESPE), Esthet X (Dentsply India), and Admira (Voco, Germany). Methods. 30 samples were fabricated for evaluation of color change using CIELAB color system and Gonioreflectometer (GK 311/M, ZEISS). 45 disc-shaped specimens were made for evaluation of surface topography after bleaching (Nupro White Gold; Dentsply) using SEM. Statistical analysis. One way ANOVA and Multiple comparison tests were used to analyze the data. Statistical significance was declared if the P value was .05 or less. Results and conclusion. All the specimens showed significant discoloration (ΔE>3.3) after their immersion in solutions representing food and beverages. The total color change after bleaching as compared to baseline color was significant in Filtek Z350 (P=.000) and Esthet X (P=.002), while it was insignificant for Admira (P=.18). Esthet X showed maximum surface roughness followed by Admira and Filtek Z350. Bleaching was effective in reducing the discoloration to a clinically acceptable value in all the three groups (ΔE