1. Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention.
- Author
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Goyal, Parag, Kim, Jiwon, Feher, Attila, Ma, Claudia L, Gurevich, Sergey, Veal, David R, Szulc, Massimiliano, Wong, Franklin J, Ratcliffe, Mark B, Levine, Robert A, Devereux, Richard B, and Weinsaft, Jonathan W
- Subjects
Heart ,Humans ,Mitral Valve Insufficiency ,Myocardial Infarction ,Echocardiography ,Stroke Volume ,Exercise Test ,Multivariate Analysis ,Logistic Models ,Risk Assessment ,Aged ,Aged ,80 and over ,Middle Aged ,Female ,Male ,Myocardial Perfusion Imaging ,Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography ,Percutaneous Coronary Intervention ,Cardiovascular ,Biomedical Imaging ,Clinical Research ,Heart Disease - Coronary Heart Disease ,Heart Disease ,mitral regurgitation ,myocardial perfusion ,single-photon emission computed tomography ,Clinical Sciences ,Cardiovascular System & Hematology - Abstract
ObjectiveIschemic mitral regurgitation (MR) is common, but its response to percutaneous coronary intervention (PCI) is poorly understood. This study tested the utility of myocardial perfusion imaging (MPI) for the stratification of MR response to PCI.MethodsMPI and transthoracic echocardiography (echo) were performed among patients undergoing PCI. MPI was used to assess stress/rest myocardial perfusion. MR was assessed via echo (performed before and after PCI).ResultsA total of 317 patients with abnormal myocardial perfusion on MPI underwent echo 25±39 days before PCI. MR was present in 52%, among whom 24% had advanced (≥moderate) MR. MR was found to be associated with left ventricular (LV) chamber dilation on MPI and echo (both P
- Published
- 2015