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5. Comparative clinical trial of diazepam with other conventional drugs in tetanus.

Author

Vassa, Nalini T., Yajnik, V. H., Joshi, K. R., Doshi, H. V., Shah, S. S., Patel, S. H., and Vassa, N T

Subjects
COMBINATION drug therapy, CLINICAL trials, COMPARATIVE studies, CLINICAL drug trials, DIAZEPAM, NEONATAL diseases, RESEARCH methodology, MEDICAL cooperation, RESEARCH, SPASMS, TETANUS, EVALUATION research, RANDOMIZED controlled trials, PHARMACODYNAMICS, THERAPEUTICS
Abstract

Results of therapeutic trial of diazepam in tetanus are presented. The trial included 200 cases of tetanus—167 non-neonates and thirty-three neonates. The patients were divided into two groups and were matched as regards age, sex and severity of the disease. The cases of group I received standard treatment while the cases of group II received diazepam in addition. Over-all mortality in group I was 54% and in group II, 26%. The results were statistically significant in non-neonates and in severe degree of tetanus. The drug was well tolerated and side effects were not observed. [ABSTRACT FROM PUBLISHER]

Published
1974

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