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1. Risk factors for ischaemic heart disease in a Cretan rural population: a twelve year follow-up study

Author

Koutis Antonios D, Kafatos Antonios G, Alegakis Athanasios K, Karalis Ioannis K, Vardas Panos E, and Lionis Christos D

Subjects
Public aspects of medicine, RA1-1270
Abstract

Abstract Background Crete has been of great epidemiological interest ever since the publication of the Seven Countries Study. In 1988 a well-defined area of rural Crete was studied, with only scarce signs of coronary heart disease (CHD) despite the unfavorable risk profile. The same population was re-examined twelve years later aiming to describe the trends of CHD risk factors over time and discuss some key points on the natural course of coronary heart disease in a rural population of Crete. Methods and Results We re-examined 200 subjects (80.7% of those still living in the area, 62.4 ± 17.0 years old). The prevalence of risk factors for CHD was high with 65.9% of men and 65.1% of women being hypertensive, 14.3% of men and 16.5% of women being diabetic, 44% of men being active smokers and more than 40% of both sexes having hyperlipidaemia. Accordingly, 77.5% of the population had a calculated Framingham Risk Score (FRS) ≥ 15%, significantly higher compared to baseline (p < 0.001). The overall occurrence rate for CHD events was calculated at 7.1 per 1000 person-years (95% confidence interval: 6.8–7.3). Conclusion The study confirms the unfavorable risk factor profile of a well defined rural population in Crete. Its actual effect on the observed incidence of coronary events in Cretans remains yet to be defined.

Published
2007
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2. CODE-EHR best-practice framework for the use of structured electronic health-care records in clinical research

Author

Kotecha, Dipak, Asselbergs, Folkert W, Achenbach, Stephan, Anker, Stefan D, Atar, Dan, Baigent, Colin, Banerjee, Amitava, Beger, Birgit, Brobert, Gunnar, Casadei, Barbara, Ceccarelli, Cinzia, Cowie, Martin R, Crea, Filippo, Cronin, Maureen, Denaxas, Spiros, Derix, Andrea, Fitzsimons, Donna, Fredriksson, Martin, Gale, Chris P, Gkoutos, Georgios V, Goettsch, Wim, Hemingway, Harry, Ingvar, Martin, Jonas, Adrian, Kazmierski, Robert, Løgstrup, Susanne, Lumbers, R Thomas, Lüscher, Thomas F, McGreavy, Paul, Piña, Ileana L, Roessig, Lothar, Steinbeisser, Carl, Sundgren, Mats, Tyl, Benoît, Thiel, Ghislaine van, Bochove, Kees van, Vardas, Panos E, Villanueva, Tiago, Vrana, Marilena, Weber, Wim, Weidinger, Franz, Windecker, Stephan, Wood, Angela, and Grobbee, Diederick E

Published
2022
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4. MicroRNAs in Atrial Fibrillation: Mechanisms, Vascular Implications, and Therapeutic Potential.

Author

Vardas, Emmanouil P., Theofilis, Panagiotis, Oikonomou, Evangelos, Vardas, Panos E., and Tousoulis, Dimitris

Subjects
ATRIAL fibrillation, NON-coding RNA, MICRORNA, OLDER people, OXIDATIVE stress
Abstract

Atrial fibrillation (AFib), the most prevalent arrhythmia in clinical practice, presents a growing global health concern, particularly with the aging population, as it is associated with devastating complications and an impaired quality of life. Its pathophysiology is multifactorial, including the pathways of fibrosis, inflammation, and oxidative stress. MicroRNAs (miRNAs), small non-coding RNA molecules, have emerged as substantial contributors in AFib pathophysiology, by affecting those pathways. In this review, we explore the intricate relationship between miRNAs and the aforementioned aspects of AFib, shedding light on the molecular pathways as well as the potential diagnostic applications. Recent evidence also suggests a possible role of miRNA therapeutics in maintenance of sinus rhythm via the antagonism of miR-1 and miR-328, or the pharmacological upregulation of miR-27b and miR-223-3p. Unraveling the crosstalk between specific miRNA profiles and genetic predispositions may pave the way for personalized therapeutic approaches, setting the tone for precision medicine in atrial fibrillation. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Estimation of recurrent atherosclerotic cardiovascular event risk in patients with established cardiovascular disease

Author

Hageman, Steven H. J., McKay, Ailsa J., Ueda, Peter, Gunn, Laura H., Jernberg, Tomas, Hagström, Emil, Bhatt, Deepak L., Steg, Ph. Gabriel, Läll, Kristi, Mägi, Reedik, Gynnild, Mari Nordbø, Ellekjær, Hanne, Saltvedt, Ingvild, Tuñón, José, Mahíllo, Ignacio, Aceña, Álvaro, Kaminski, Karol, Chlabicz, Malgorzata, Sawicka, Emilia, Tillman, Taavi, McEvoy, John W., di Angelantonio, Emanuele, Graham, Ian, de Bacquer, Dirk, Ray, Kausik K., Dorresteijn, Jannick A. N., Visseren, Frank L. J., Asselbergs, F. W., Nathoe, H. M., de Borst, G. J., Bots, M. L., Geerlings, M. I., Emmelot, M. H., de Jong, P. A., Leiner, T., Lely, A. T., van der Kaaij, N. P., Kappelle, L. J., Ruigrok, Y. M., Verhaar, M. C., Visseren, F. L. J., Westerink, J., Halle, Martin, Timmis, Adam D., Lettino, Maddalena, Vardas, Panos E., McEvoy, John William, Graham, Ian M., and Academic Medical Center

Subjects
Cardiac & Cardiovascular Systems, PREDICTION, Myocardial Infarction, Residual risk, Risk Assessment, ARTERIAL-DISEASE, Recurrent risk, Risk Factors, Medicine and Health Sciences, Humans, Cardiac and Cardiovascular Systems, 1102 Cardiorespiratory Medicine and Haematology, METAANALYSIS, Science & Technology, Kardiologi, Secondary prevention, 1103 Clinical Sciences, ASSOCIATION, Atherosclerosis, Established ASCVD, COMPETING RISKS, PREVENTION, Risk prediction, Stroke, ASPIRIN, Cardiovascular System & Hematology, Cardiovascular Diseases, CLINICAL-PRACTICE, Personalized treatment, Cardiovascular System & Cardiology, Cardiology and Cardiovascular Medicine, OUTPATIENTS, Life Sciences & Biomedicine, Algorithms, Biomarkers, TASK-FORCE
Abstract

Aims The 10-year risk of recurrent atherosclerotic cardiovascular disease (ASCVD) events in patients with established ASCVD can be estimated with the Secondary Manifestations of ARTerial disease (SMART) risk score, and may help refine clinical management. To broaden generalizability across regions, we updated the existing tool (SMART2 risk score) and recalibrated it with regional incidence rates and assessed its performance in external populations. Methods and results Individuals with coronary artery disease, cerebrovascular disease, peripheral artery disease, or abdominal aortic aneurysms were included from the Utrecht Cardiovascular Cohort-SMART cohort [n = 8355; 1706 ASCVD events during a median follow-up of 8.2 years (interquartile range 4.2-12.5)] to derive a 10-year risk prediction model for recurrent ASCVD events (non-fatal myocardial infarction, non-fatal stroke, or cardiovascular mortality) using a Fine and Gray competing risk-adjusted model. The model was recalibrated to four regions across Europe, and to Asia (excluding Japan), Japan, Australia, North America, and Latin America using contemporary cohort data from each target region. External validation used data from seven cohorts [Clinical Practice Research Datalink, SWEDEHEART, the international REduction of Atherothrombosis for Continued Health (REACH) Registry, Estonian Biobank, Spanish Biomarkers in Acute Coronary Syndrome and Biomarkers in Acute Myocardial Infarction (BACS/BAMI), the Norwegian COgnitive Impairment After STroke, and Bialystok PLUS/Polaspire] and included 369 044 individuals with established ASCVD of whom 62 807 experienced an ASCVD event. C-statistics ranged from 0.605 [95% confidence interval (CI) 0.547-0.664] in BACS/BAMI to 0.772 (95% CI 0.659-0.886) in REACH Europe high-risk region. The clinical utility of the model was demonstrated across a range of clinically relevant treatment thresholds for intensified treatment options. Conclusion The SMART2 risk score provides an updated, validated tool for the prediction of recurrent ASCVD events in patients with established ASCVD across European and non-European populations. The use of this tool could allow for a more personalized approach to secondary prevention based upon quantitative rather than qualitative estimates of residual risk. Key objective To improve upon prediction of 10-year residual atherosclerotic cardiovascular disease (ASCVD) event risk in individuals with established ASCVD, by taking into account competing risks and geographical differences in ASCVD incidence. Key findings Derivation in 8355 individuals with established ASCVD from the Utrecht Cardiovascular Cohort-Secondary Manifestations of ARTerial disease (SMART) cohort. C-statistics ranged from 0.605 [95% confidence interval (CI) 0.547-0.664] to 0.772 (95% CI 0.659-0.886). Clinical utility was demonstrated across a range of treatment thresholds relevant to therapy intensification. Take-home messages The SMART2 risk score can be used to estimate 10-year residual risk of fatal and non-fatal ASCVD in individuals with established ASCVD. Adapted to the CVD incidence in several global regions. Facilitates shared decision-making on Step 2 prevention goals as recommended by the 2021 ESC Guidelines on cardiovascular prevention.

Published
2022

17. CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research

Author

Kotecha, Dipak, Asselbergs, Folkert W, Achenbach, Stephan, Anker, Stefan D, Atar, Dan, Baigent, Colin, Banerjee, Amitava, Beger, Birgit, Brobert, Gunnar, Casadei, Barbara, Ceccarelli, Cinzia, Cowie, Martin R, Crea, Filippo, Cronin, Maureen, Denaxas, Spiros, Derix, Andrea, Fitzsimons, Donna, Fredriksson, Martin, Gale, Chris P, Gkoutos, Georgios V, Goettsch, Wim, Hemingway, Harry, Ingvar, Martin, Jonas, Adrian, Kazmierski, Robert, Løgstrup, Susanne, Thomas Lumbers, R, Lüscher, Thomas F, McGreavy, Paul, Piña, Ileana L, Roessig, Lothar, Steinbeisser, Carl, Sundgren, Mats, Tyl, Benoît, van Thiel, Ghislaine, van Bochove, Kees, Vardas, Panos E, Villanueva, Tiago, Vrana, Marilena, Weber, Wim, Weidinger, Franz, Windecker, Stephan, Wood, Angela, Grobbee, Diederick E, Kurz, Xavier, Concato, John, Morales, Jose Pablo, Piña, Ileana, Hedberg, Niklas, Spencer, Stuart, Sarkar, Rupa, Tyl, Benoit, Carroll, Colm, Thompson, Ceri, Tursini, Valentina, Cowie, Martin, Lumbers, R Tom, Grobbee, Rick, Van Thiel, Ghislaine, Gkoutos, George V, Petrova, Ana, Baljevic, Katija, Vairami, Polyxeni, Taylor, Jennifer, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Kotecha, Dipak [0000-0002-2570-9812], and Apollo - University of Cambridge Repository

Subjects
Medicine(all), Science & Technology, Cardiac & Cardiovascular Systems, COVID-19, 610 Medicine & health, 1103 Clinical Sciences, General Medicine, Guidelines, Networking and Information Technology R&D, Cardiovascular System & Hematology, Innovative Medicines Initiative BigData@Heart Consortium, European Society of Cardiology, CODE-EHR international consensus group, Epidemiology strobe statement, Cardiovascular System & Cardiology, Electronic Health Records, Humans, Generic health relevance, Electronics, Cardiology and Cardiovascular Medicine, Life Sciences & Biomedicine, Delivery of Health Care, Pandemics, 1102 Cardiorespiratory Medicine and Haematology, Software
Abstract

Big data is central to new developments in global clinical science aiming to improve the lives of patients. Technological advances have led to the routine use of structured electronic healthcare records with the potential to address key gaps in clinical evidence. The covid-19 pandemic has demonstrated the potential of big data and related analytics, but also important pitfalls. Verification, validation, and data privacy, as well as the social mandate to undertake research are key challenges. The European Society of Cardiology and the BigData@Heart consortium have brought together a range of international stakeholders, including patient representatives, clinicians, scientists, regulators, journal editors and industry. We propose the CODE-EHR Minimum Standards Framework as a means to improve the design of studies, enhance transparency and develop a roadmap towards more robust and effective utilisation of healthcare data for research purposes.

Published
2022

18. CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research

Author

Kotecha, Dipak, primary, Asselbergs, Folkert W, additional, Achenbach, Stephan, additional, Anker, Stefan D, additional, Atar, Dan, additional, Baigent, Colin, additional, Banerjee, Amitava, additional, Beger, Birgit, additional, Brobert, Gunnar, additional, Casadei, Barbara, additional, Ceccarelli, Cinzia, additional, Cowie, Martin R, additional, Crea, Filippo, additional, Cronin, Maureen, additional, Denaxas, Spiros, additional, Derix, Andrea, additional, Fitzsimons, Donna, additional, Fredriksson, Martin, additional, Gale, Chris P, additional, Gkoutos, Georgios V, additional, Goettsch, Wim, additional, Hemingway, Harry, additional, Ingvar, Martin, additional, Jonas, Adrian, additional, Kazmierski, Robert, additional, Løgstrup, Susanne, additional, Lumbers, R Thomas, additional, Lüscher, Thomas F, additional, McGreavy, Paul, additional, Piña, Ileana L, additional, Roessig, Lothar, additional, Steinbeisser, Carl, additional, Sundgren, Mats, additional, Tyl, Benoît, additional, van Thiel, Ghislaine, additional, van Bochove, Kees, additional, Vardas, Panos E, additional, Villanueva, Tiago, additional, Vrana, Marilena, additional, Weber, Wim, additional, Weidinger, Franz, additional, Windecker, Stephan, additional, Wood, Angela, additional, and Grobbee, Diederick E, additional

Published
2022
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21. CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research

Author

Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Kotecha, Dipak, Asselbergs, Folkert W., Achenbach, Stephan, Anker, Stefan D., Atar, Dan, Baigent, Colin, Banerjee, Amitava, Beger, Birgit, Brobert, Gunnar, Casadei, Barbara, Ceccarelli, Cinzia, Cowie, Martin R., Crea, Filippo, Cronin, Maureen, Denaxas, Spiros, Derix, Andrea, Fitzsimons, Donna, Fredriksson, Martin, Gale, Chris P., Gkoutos, Georgios V., Goettsch, Wim, Hemingway, Harry, Ingvar, Martin, Jonas, Adrian, Kazmierski, Robert, Løgstrup, Susanne, Lumbers, R. Thomas, Lüscher, Thomas F., McGreavy, Paul, Piña, Ileana L., Roessig, Lothar, Steinbeisser, Carl, Sundgren, Mats, Tyl, Benoît, Van Thiel, Ghislaine, Van Bochove, Kees, Vardas, Panos E., Villanueva, Tiago, Vrana, Marilena, Weber, Wim, Weidinger, Franz, Windecker, Stephan, Wood, Angela, Grobbee, Diederick E., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Kotecha, Dipak, Asselbergs, Folkert W., Achenbach, Stephan, Anker, Stefan D., Atar, Dan, Baigent, Colin, Banerjee, Amitava, Beger, Birgit, Brobert, Gunnar, Casadei, Barbara, Ceccarelli, Cinzia, Cowie, Martin R., Crea, Filippo, Cronin, Maureen, Denaxas, Spiros, Derix, Andrea, Fitzsimons, Donna, Fredriksson, Martin, Gale, Chris P., Gkoutos, Georgios V., Goettsch, Wim, Hemingway, Harry, Ingvar, Martin, Jonas, Adrian, Kazmierski, Robert, Løgstrup, Susanne, Lumbers, R. Thomas, Lüscher, Thomas F., McGreavy, Paul, Piña, Ileana L., Roessig, Lothar, Steinbeisser, Carl, Sundgren, Mats, Tyl, Benoît, Van Thiel, Ghislaine, Van Bochove, Kees, Vardas, Panos E., Villanueva, Tiago, Vrana, Marilena, Weber, Wim, Weidinger, Franz, Windecker, Stephan, Wood, Angela, and Grobbee, Diederick E.

Published
2022

22. CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research

Author

Cardiologie, Onderzoek Precision medicine, Team Medisch, Circulatory Health, Medical Humanities Onderzoek Team 1, JC onderzoeksprogramma Methodologie, Global Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Kotecha, Dipak, Asselbergs, Folkert W., Achenbach, Stephan, Anker, Stefan D., Atar, Dan, Baigent, Colin, Banerjee, Amitava, Beger, Birgit, Brobert, Gunnar, Casadei, Barbara, Ceccarelli, Cinzia, Cowie, Martin R., Crea, Filippo, Cronin, Maureen, Denaxas, Spiros, Derix, Andrea, Fitzsimons, Donna, Fredriksson, Martin, Gale, Chris P., Gkoutos, Georgios V., Goettsch, Wim, Hemingway, Harry, Ingvar, Martin, Jonas, Adrian, Kazmierski, Robert, Løgstrup, Susanne, Lumbers, R. Thomas, Lüscher, Thomas F., McGreavy, Paul, Piña, Ileana L., Roessig, Lothar, Steinbeisser, Carl, Sundgren, Mats, Tyl, Benoît, Van Thiel, Ghislaine, Van Bochove, Kees, Vardas, Panos E., Villanueva, Tiago, Vrana, Marilena, Weber, Wim, Weidinger, Franz, Windecker, Stephan, Wood, Angela, Grobbee, Diederick E., Cardiologie, Onderzoek Precision medicine, Team Medisch, Circulatory Health, Medical Humanities Onderzoek Team 1, JC onderzoeksprogramma Methodologie, Global Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Kotecha, Dipak, Asselbergs, Folkert W., Achenbach, Stephan, Anker, Stefan D., Atar, Dan, Baigent, Colin, Banerjee, Amitava, Beger, Birgit, Brobert, Gunnar, Casadei, Barbara, Ceccarelli, Cinzia, Cowie, Martin R., Crea, Filippo, Cronin, Maureen, Denaxas, Spiros, Derix, Andrea, Fitzsimons, Donna, Fredriksson, Martin, Gale, Chris P., Gkoutos, Georgios V., Goettsch, Wim, Hemingway, Harry, Ingvar, Martin, Jonas, Adrian, Kazmierski, Robert, Løgstrup, Susanne, Lumbers, R. Thomas, Lüscher, Thomas F., McGreavy, Paul, Piña, Ileana L., Roessig, Lothar, Steinbeisser, Carl, Sundgren, Mats, Tyl, Benoît, Van Thiel, Ghislaine, Van Bochove, Kees, Vardas, Panos E., Villanueva, Tiago, Vrana, Marilena, Weber, Wim, Weidinger, Franz, Windecker, Stephan, Wood, Angela, and Grobbee, Diederick E.

Published
2022

23. Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease

Author

Epi Methoden Team 3, Infection & Immunity, Team Medisch, Circulatory Health, Epi Methoden, Cancer, JC onderzoeksprogramma Methodology, van Smeden, Maarten, Heinze, Georg, Van Calster, Ben, Asselbergs, Folkert W, Vardas, Panos E, Bruining, Nico, de Jaegere, Peter, Moore, Jason H, Denaxas, Spiros, Boulesteix, Anne-Laure, Moons, Karel G M, Epi Methoden Team 3, Infection & Immunity, Team Medisch, Circulatory Health, Epi Methoden, Cancer, JC onderzoeksprogramma Methodology, van Smeden, Maarten, Heinze, Georg, Van Calster, Ben, Asselbergs, Folkert W, Vardas, Panos E, Bruining, Nico, de Jaegere, Peter, Moore, Jason H, Denaxas, Spiros, Boulesteix, Anne-Laure, and Moons, Karel G M

Published
2022

24. The year in cardiovascular medicine 2021: digital health and innovation

Author

Cardiologie, Team Medisch, Circulatory Health, Epi Methoden Team 3, Infection & Immunity, Vardas, Panos E., Asselbergs, Folkert W., van Smeden, Maarten, Friedman, Paul, Cardiologie, Team Medisch, Circulatory Health, Epi Methoden Team 3, Infection & Immunity, Vardas, Panos E., Asselbergs, Folkert W., van Smeden, Maarten, and Friedman, Paul

Published
2022

34. HRS Expert Consensus Statement on the Management of Cardiovascular Implantable Electronic Devices (CIEDs) in patients nearing end of life or requesting withdrawal of therapy: This document was developed in collaboration and endorsed by the American College of Cardiology (ACC), the American Geriatrics Society (AGS), the American Academy of Hospice and Palliative Medicine (AAHPM); the American Heart Association (AHA), the European Heart Rhythm Association (EHRA), and the Hospice and Palliative Nurses Association (HPNA)

Author

Lampert, Rachel, Hayes, David L., Annas, George J., Farley, Margaret A., Goldstein, Nathan E., Hamilton, Robert M., Kay, G. Neal, Kramer, Daniel B., Mueller, Paul S., Padeletti, Luigi, Pozuelo, Leo, Schoenfeld, Mark H., Vardas, Panos E., Wiegand, Debra L., and Zellner, Richard

Published
2010
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44. Clinical characteristics and management of patients with diabetes mellitus and stable coronary artery disease in daily clinical practice. The SCAD-DM Registry

Author

Marketou, Maria E. Vlachopoulos, Charalambos Hahalis, George and Kafkala, Kristalenia Kouvelas, Nikolaos Mantas, Ioannis and Sideris, Antonios Pisimisis, Evaggelos Vardas, Emmanouel P. and Tzeis, Stylianos Vardas, Panos E. Collaborators Hosp Clinics and Collaborators Private Practice Off

Abstract

Background: Patients with diabetes mellitus (DM) and coronary artery disease (CAD) represent a high-risk population, where comorbidities are common and the progression of coronary heart disease is relatively rapid and extensive. The present survey, conducted nationwide in a Eurozone country, Greece, with a properly organized national health system, aimed to record specific data from a significant number of patients with diabetes and documented stable CAD (SCAD). Methods and results: We conducted our survey across the country, in private and public primary, secondary, and tertiary care centers. A total of 1900 patients aged 71 +/- 10 years old who suffered from both DM and chronic coronary syndromes were registered. Of the patients registered, 574 (30.24%) were women. It was found that 506 (26.6%) of the 1900 surveyed patients showed typical angina symptoms, while another 560 (29.5%) patients had developed angina-equivalent symptoms according to their history. Additionally, 324 (17%) patients had atypical symptoms that could not easily be attributed to existing CAD and the remaining 510 (26.8%) of the 1900 patients did not exhibit any angina symptoms during their daily activities. Functional testing for myocardial ischemia was not performed in 833 patients (43.8%). Myocardial scintigraphy was the most commonly used noninvasive technique (644 patients, 34%), while 492 patients (25.9%) had an exercise test and 159 (8.4%) underwent stress echocardiography. Conclusion: Real-world data in this specific high-risk population of diabetic patients with SCAD offer the opportunity to identify and improve diagnostic and therapeutic practice in the healthcare system of a European Union country. (C) 2020 Hellenic Society of Cardiology. Publishing services by Elsevier B.V.

Published
2021

45. SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions

Author

Interne Geneeskunde Vasculaire, MS Interne Geneeskunde, Circulatory Health, MS Geriatrie, de Vries, Tamar, I, Cooney, Marie Therese, Selmer, Randi M., Hageman, Steven H. J., Pennells, Lisa A., Wood, Angela, Kaptoge, Stephen, Xu, Zhe, Westerink, Jan, Rabanal, Kjersti S., Tell, Grethe S., Meyer, Haakon E., Igland, Jannicke, Ariansen, Inger, Matsushita, Kunihiro, Blaha, Michael J., Nambi, Vijay, Peters, Ruth, Beckett, Nigel, Antikainen, Riitta, Bulpitt, Christopher J., Muller, Majon, Emmelot-Vonk, Marielle H., Trompet, Stella, Jukema, Wouter, Ference, Brian A., Halle, Martin, Timmis, Adam D., Vardas, Panos E., Dorresteijn, Jannick A. N., De Bacquer, Dirk, Di Angelantonio, Emanuele, Visseren, Frank L. J., Graham, Ian M., Interne Geneeskunde Vasculaire, MS Interne Geneeskunde, Circulatory Health, MS Geriatrie, de Vries, Tamar, I, Cooney, Marie Therese, Selmer, Randi M., Hageman, Steven H. J., Pennells, Lisa A., Wood, Angela, Kaptoge, Stephen, Xu, Zhe, Westerink, Jan, Rabanal, Kjersti S., Tell, Grethe S., Meyer, Haakon E., Igland, Jannicke, Ariansen, Inger, Matsushita, Kunihiro, Blaha, Michael J., Nambi, Vijay, Peters, Ruth, Beckett, Nigel, Antikainen, Riitta, Bulpitt, Christopher J., Muller, Majon, Emmelot-Vonk, Marielle H., Trompet, Stella, Jukema, Wouter, Ference, Brian A., Halle, Martin, Timmis, Adam D., Vardas, Panos E., Dorresteijn, Jannick A. N., De Bacquer, Dirk, Di Angelantonio, Emanuele, Visseren, Frank L. J., and Graham, Ian M.

Published
2021

48. Guidelines for the management of atrial fibrillation: The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)

Author

Camm, A. John, Kirchhof, Paulus, Lip, Gregory Y.H., Schotten, Ulrich, Savelieva, Irene, Ernst, Sabine, Van Gelder, Isabelle C., Al-Attar, Nawwar, Hindricks, Gerhard, Prendergast, Bernard, Heidbuchel, Hein, Alfieri, Ottavio, Angelini, Annalisa, Atar, Dan, Colonna, Paolo, De Caterina, Raffaele, De Sutter, Johan, Goette, Andreas, Gorenek, Bulent, Heldal, Magnus, Hohloser, Stefan H., Kolh, Philippe, Le Heuzey, Jean-Yves, Ponikowski, Piotr, Rutten, Frans H., Vahanian, Alec, Auricchio, Angelo, Bax, Jeroen, Ceconi, Claudio, Dean, Veronica, Filippatos, Gerasimos, Funck-Brentano, Christian, Hobbs, Richard, Kearney, Peter, McDonagh, Theresa, Popescu, Bogdan A., Reiner, Zeljko, Sechtem, Udo, Sirnes, Per Anton, Tendera, Michal, Vardas, Panos E., Widimsky, Petr, Vardas, Panos E., Agladze, Vazha, Aliot, Etienne, Balabanski, Tosho, Blomstrom-Lundqvist, Carina, Capucci, Alessandro, Crijns, Harry, Dahlöf, Björn, Folliguet, Thierry, Glikson, Michael, Goethals, Marnix, Gulba, Dietrich C., Ho, Siew Yen, Klautz, Robert J. M., Kose, Sedat, McMurray, John, Perrone Filardi, Pasquale, Raatikainen, Pekka, Salvador, Maria Jesus, Schalij, Martin J., Shpektor, Alexander, Sousa, João, Stepinska, Janina, Uuetoa, Hasso, Zamorano, Jose Luis, and Zupan, Igor

Published
2010
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