346 results on '"Vanhaesebroeck, B"'
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2. Structural and Functional Diversity of Phosphoinositide 3-Kinases [and Discussion]
3. Crystal structure of the apo p110alpha catalytic subunit from homo sapiens
4. Crystal structure of the p110alpha catalytic subunit from homo sapiens in complex with activator 1938
5. Crystal Structure of PI3Kalpha in complex with the inhibitor NVP-BYL719
6. Tumor Necrosis Factor: Mechanism of Action and its Potential for Anticancer Therapy
7. Direct and indirect actions of PI 3-kinase in cancer cell growth control
8. A selective inhibitor of the p110δ isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16
9. The phosphoinositide 3-kinase β and δ regulate osteoclast development and function: 7.06
10. The phosphoinositide 3-kinase β regulates osteoclastic bone resorption: 1.94
11. The phosphoinositide 3-kinase β regulates osteoclast development and in vivo bone homeostasis: 161
12. FINE-TUNING OF NEUROEXOCYTOSIS BY TWO MEMBERS OF THE PI3-KINASE FAMILY: TYPE I PI3KDELTA AND TYPE II PI3K-C2ALPHA: S03-03
13. Structure - Functton Relationship of Tumour Necrosis Factor and its Mechanism of Action
14. Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
15. CD28 engagement promotes T cell migration and antigen-independent T cell: dendritic cell interactions: 2.7
16. Plasma concentrations of pralidoxime methylsulphate in organophosphorus poisoned patients
17. Essential role for the p110δ phosphoinositide 3-kinase in the allergic response: 6.5
18. The role of PI 3-kinases in airway inflammation: IS6
19. Signaling by PI 3-kinase isoforms
20. The roles of tyrosine-kinase linked PI 3-kinase isoforms: SL04-028
21. PI3K signalling in T cells
22. Impaired B and T-cell antigen receptor signalling in 110δ PI 3-kinase mutant mice
23. The beta isoform of the p110 catalytic subunit of phosphoinositide-3-kinase mediates chemotaxis of vascular smooth muscle cells exposed to a high glucose concentration: P38
24. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
25. Insights into the biology of class I PI3K isoforms and translation to the clinic
26. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
27. Tumour Necrosis Factor and Interleukin-6: Structure and Mechanism of Action of the Molecular, Cellular and in Vivo Level
28. Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
29. Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
30. The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells
31. Phosphoinositide 3-kinase in T cell activation and survival
32. 33IN - Insights into the biology of class I PI3K isoforms and translation to the clinic
33. Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells
34. Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the P13K and MAPK signalling pathways
35. Tumor Necrosis Factor: Mechanism of Action at the Molecular, Cellular and in vivo Level
36. In vitro and in vivo Action of Tumor Necrosis Factor1
37. Two Pathways of Tumor Necrosis Factor Signal Transduction: In vitro and in vivo Implications
38. 566: Investigating PI3Kinase and K-ras pathway interactions in mouse model of colorectal cancer
39. The PI3K-PDK1 connection: more than just a road to PKB
40. THU0045 Epratuzumab, an Antibody Targeting CD22 on B Cells, Induces Phosphoprotein Changes Following B-Cell Receptor Activation in Vitro
41. PIK3CD (phosphoinositide-3-kinase, catalytic, delta polypeptide)
42. A human phosphatidylinositol 3-kinase complex related to yeast Vps34p-Vps15p protein sorting system
43. 104 Plasma metabolomic analysis of genetic and pharmacological manipulation of PI 3-kinase pathway activation in mice using liquid chromatography coupled to mass spectrometry (LC-MS)
44. 5 INVITED Biological roles of PI 3-kinase isoforms
45. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions: evidence for the involvment of mitochondrial radical generation
46. The PI 3-kinase isoforms p110(alpha) and p110(beta) have differental roles in PDGF- and insulin-mediated signaling.
47. 107 INVITED Biological roles of PI 3-kinase isoforms
48. Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?
49. Tumor-necrosis-factor : mechanism of action at the molecular, cellular and invivo level
50. CLASS I PI3K ISOFORMS ?? AND ?? REGULATE KEY RESPONSES OF CERULEIN-INDUCED PANCREATITIS. PI3K?? IS NECESSARY FOR TRYPSIN ACTIVATION
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