1. Maternal Side-Effects After Multiple Courses of Antenatal Corticosteroids (MACS): The Three- Month Follow-Up of Women in the Randomized Controlled Trial of MACS for Preterm Birth Study
- Author
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Murphy, Kellie E., Hannah, Mary E., Willan, Andrew R., Ohlsson, Arne, Kelly, Edmond N., Matthews, Stephen G., Saigal, Saroj, Asztalos, Elizabeth, Ross, Sue, Delisle, Marie-France, Tomat, Laura, Amankwah, Kofi, Guselle, Patricia, Gafni, Amiram, Lee, Shoo K., Anthony Armson, B., Group, for the MACS Collaborative, Murphy, Kellie E., Amankwah, Kofi, Armson, B. Anthony, Asztalos, Elizabeth, Delisle, MarieFrance, Gafni, Amiram, Guselle, Patricia, Hannah, Mary E., Hewson, Sheila A., Kelly, Edmond N., Lee, Shoo K., Matthews, Stephen G., Ohlsson, Arne, Ross, Sue, Rovet, Joanne, Saigal, Saroj, Sananes, Renee, Schmid, Isabelle, Willan, Andrew R., Kwiatkowski, Leonardo, Tortorella, Susana Marisa, Bertin, Marta Susana, Castaldi, José Luis, Deguer, Carlos, Klun, Milton, Besegato, Cintia, Izbizky, Gustavo, Vaneri, Maria Cristina, Fustinana, Carlos Alberto, Otano, Lucas, Palermo, Mario S.F., Murua, Emerson Javier, Valera, Dolores Montes, Sampietro, Hector, Monaco, Antonio, Savransky, Argentina Ricardo, Dunaiewsky, Armando, Basualdo, Maria Natalia, Andina, Elsa, Di Marco, Ingrid, Rivero, Mabel, Feu, Maria Celeste, Garcia, Sergio, Aguirre, Jesus Daniel, Morales, Elba Mirta, Ayala, Liana Elisa, De Sagastizabal, Maria Teresa, Abreo, Griselda, Uranga, Alfredo, Martin, Raquel de Lourdes, Arias, Carlos, Gorostiaga, Raul Abalos, Curioni, Miguel, Alvarado, Jorge, Fuchtner, Carlos, Flores, Desiree Mostajo, Tonoli Tessari, Dilma Maria, Madi, Jose Mauro, de Lorenzi, Dino Roberto Soares, Mattana, Maria do Carmo, Brunstein, Carla, Trapani, Alberto, Schmaltz, Luiza, de Souza, Goianice Ribero, de Assis, Maria Elaine, Melo Melgaco, Irene Angela, Moreira de Sa, Renato Augusto, Bornia, Rita Guerios, Demianczuk, Nestor N, Penttinen, Elizabeth, Butt, Kimberly, Hay, Kathryn, Sandwich, Vicki, Armson, B Anthony, Vincer, Michael, Allen, Victoria, Fanning, Cora, Kulkarni, Ramesh, Laplante, Joanne, Carson, George D, Williams, Suzanne, Holfeld, Sandy, Olatunbosun, Femi, Dalton, Shirley, Henry, April, Haughian, Janna, Moutquin, Jean-Marie, Blouin, Daniel, Bédard, Suzanne Kocsis, Murphy, Kellie, Ohlsson, Arne, Kelly, Edmond, Jordan, Anne, Shapiro, Jodi, Asztalos, Elizabeth, Barrett, Jon, Cohen, Howard, Andrews, Leigh, Owen, Holly, Delisle, Marie-France, Popovska, Vesna, Soanes, Shelley, Helewa, Michael E, Kenny-Lodewyks, Doris, Gomez, Ricardo, Silva, Karla, Poblete, Jorge Figueroa, Ferrand, Pedro, Belmar, Cristian, Vera, Claudio, Su, Qi Feng, Gu, Wei, Liu, Zhi Wei, Flores, Martha Marrugo, Santoro, Carlos Malabet, Ortiz, Edgar Ivan, Torres, Javier, Rodriguez, Adriana, Hvidman, Lone, Mouritzen, Anne, Vikre-Jørgensen, Jennifer, Hopp, Hartmut, Nonnenmacher, Andreas, Braig, Ute, Berg, Christoph, Bizjak, Gabriele, Gembruch, Ulrich, Schwarzer, Verena, Hoyme, U B, Bittrich, Hans-Jorg, Oletzky, Britta, Schneider, Joachim, Hollwitz, Bettina, Oehler, Katrin, Dressler, Frank, Ertan, A Kubilay, Hentschel, Juliane, Mack, Annegret, Schmidt, W., Faber, Renaldo, Stepan, Holger, Kuhnert, Maritta, Stiller, Susanne, Kuschel, Bettina, Schneider, K.T.M., Zimmermann, Andrea, Krause, Michael, Gröbe, H, Terzioglu, Neslisah, Seelbach-Goebel, Birgit, Falkert, Andreas, Mueller, Karin, Voss, Hana, Major, Tamas, Zoärd, Krasznai, Bartha, Tünde, Bea, Polonkai, Zsadänyi, Judit, Nachum, Zohar, Peniakov, Marina, Hallak, Mordechai, Harlev, Avraham, Harel, Linda, Chayen, Benny, Siev, Sima, Samberg, Ichel, Wolff, Leslie, Sadan, Oscar, Elyassi, Anat, Baider, Carolina, Kohelet, David, Golan, Abraham, Mankuta, David, Bar-Oz, Benjamin, Combs, Danielle, Rosen, Doron J.D., Kaneti, Hagai Y., Tzachi, Tal, Zausmer, Janice, Maman, Maor, Perri, Tamar, Taitelboum, Shani, Simchen, Michal, Shalev, Gilat, Goldinfeld, Michael, Levine, Orit, El-Zibdeh, Mazen Y, Al-Faris, Lama T, Ayyash, Hussein A, Ugarte, Pedro Saona, Preis, Krzysztof, Domzalska-Popadiuk, Iwona, Swiatkowska-Freund, Malgorzata, Janczewska, Iwona, Wilczynski, Jan, Krekora, Michael, Kesiak, Marcin, Gulczynska, Ewa, Ropacka, Mariola, Madejczyk, Mateusz, Rozycka, Joanna, Breborowicz, Grzegorz H, Szymankiewicz, Marta, Borzova, Nadezhda, Posiseeva, Lubov V, Khodjaeva, Zulfiya, Vikhlyaeva, Ekaterina, Palacio, Montse, Salvia, Dolors, Botet, Francesc, Massanes, Marta, Lopez, Marta, Hösli, Irene, Holzgreve, Wolfgang, Voekt, Cora A., Belhia, Fadhil, Hohlfeld, Patrick, Prince-dit-Clottu, Edmond, Beinder, Ernst, von Mandach, Ursula, Fauchere, Jean-Claude, Roumen, Frans J.M.E., Pieters, Mijntje, Smits, Frans, Bolaji, Ibrahim I, Adiotomre, Pauline, Al-Taher, Hamed, Barnes, Hayley, Abdul-Kadir, Rezan, Chi, Claudia, Van Someren, Vivienne, Dexter, Scott, Samelson, Renee, Horgan, Michael J, Valentini, Cathryn, Pardanani, Setul, Bebbington, Michael, Chazotte, Cynthia, Kilpatrick, Sarah, Drahos, Jessica L., Saldana, Luis, Mount, Beverly, Warner, Barbara, Wedig, Kathy, Lysikiewicz, Andrzej, Bsat, Fadi, Fleming, Jennie, Lee, Alison, Hoffman, Despina, Bracken, Michael, Crowley, Patricia, Donner, Allan, Duley, Lelia, and Tyson, Jon
- Abstract
A single course of antenatal corticosteroids (ACS) is associated with a reduction in respiratory distress syndrome and neonatal death. Multiple Courses of Antenatal Corticosteroids Study(MACS), a study involving 1858 women, was a multicentre randomized placebo-controlled trial of multiple courses of ACS, given every 14 days until 33+6 weeks or birth, whichever came first. The primary outcome of the study, a composite of neonatal mortality and morbidity, was similar for the multiple ACS and placebo groups (12.9% vs. 12.5%), but infants exposed to multiple courses of ACS weighed less, were shorter, and had smaller head circumferences. Thus for women who remain at increased risk of preterm birth, multiple courses of ACS (every 14 days) are not recommended. Chronic use of corticosteroids is associated with numerous side effects including weight gain and depression The aim of this postpartum assessment was to ascertain if multiple courses of ACS were associated with maternal side effects.
- Published
- 2011
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