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19 results on '"Vandorpe, Michael"'

4. TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance

Author

Wang, Jie, primary, Jiang, Qihang, additional, Pleskot, Roman, additional, Grones, Peter, additional, Bahafid, Elmehdi, additional, Denay, Grégoire, additional, Galván‐Ampudia, Carlos, additional, Xu, Xiangyu, additional, Vandorpe, Michael, additional, Mylle, Evelien, additional, De Smet, Ive, additional, Vernoux, Teva, additional, Simon, Rüdiger, additional, Nowack, Moritz K, additional, and Van Damme, Daniel, additional

Published
2023
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5. Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants

Author

Damme, Daniël Van, primary, Dragwidge, Jonathan, additional, Wang, Yanning, additional, Brocard, Lysiane, additional, De Meyer, Andreas, additional, Hudeček, Roman, additional, eeckhout, Dominique, additional, Grones, Peter, additional, Buridan, Matthieu, additional, Chambaud, Clément, additional, Pejchar, Přemysl, additional, Potocký, Martin, additional, Winkler, Joanna, additional, Vandorpe, Michael, additional, Serre, Nelson, additional, Fendrych, Matyas, additional, Bernard, Amélie, additional, De Jaeger, Geert, additional, Pleskot, Roman, additional, and Fang, Xiaofeng, additional

Published
2023
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8. TPLATE complex dependent endocytosis is required for shoot apical meristem maintenance by attenuating CLAVATA1 signaling

Author

Wang, Jie, primary, Jiang, Qihang, additional, Pleskot, Roman, additional, Grones, Peter, additional, Denay, Grégoire, additional, Galván-Ampudia, Carlos, additional, Bahafid, Elmehdi, additional, Xu, Xiangyu, additional, Vandorpe, Michael, additional, Mylle, Evelien, additional, De Smet, Ive, additional, Vernoux, Teva, additional, Simon, Rüdiger, additional, Nowack, Moritz K., additional, and Van Damme, Daniel, additional

Published
2022
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9. Mapping the adaptor protein complex interaction network in Arabidopsis identifies P34 as a common stability regulator

Author

Wang, Peng, primary, Siao, Wei, additional, Zhao, Xiuyang, additional, Arora, Deepanksha, additional, Wang, Ren, additional, Eeckhout, Dominique, additional, Leene, Jelle Van, additional, Kumar, Rahul, additional, Houbaert, Anaxi, additional, Winne, Nancy De, additional, Mylle, Evelien, additional, Vandorpe, Michael, additional, Korver, Ruud A., additional, Testerink, Christa, additional, Gevaert, Kris, additional, Vanneste, Steffen, additional, Jaeger, Geert De, additional, Damme, Daniël Van, additional, and Russinova, Eugenia, additional

Published
2022
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10. The transcription factor AtMYB12 is part of a feedback loop regulating cell division orientation in the root meristem vasculature.

Author

Wybouw, Brecht, Arents, Helena E, Yang, Baojun, Nolf, Jonah, Smet, Wouter, Vandorpe, Michael, Minne, Max, Luo, Xiaopeng, Clercq, Inge De, Damme, Daniël Van, Glanc, Matouš, and Rybel, Bert De

Subjects
CELL division, TRANSCRIPTION factors, GENE regulatory networks, MERISTEMS, BLOOD vessels
Abstract

Transcriptional networks are crucial to integrate various internal and external signals into optimal responses during plant growth and development. In Arabidopsis thaliana , primary root vasculature patterning and proliferation are controlled by a network centred around the basic Helix-Loop-Helix transcription factor complex, formed by TARGET OF MONOPTEROS 5 (TMO5) and LONESOME HIGHWAY (LHW), which control cell proliferation and division orientation by modulating the cytokinin response and other downstream factors. Despite recent progress, many aspects of the TMO5/LHW pathway are not fully understood. In particular, the upstream regulators of TMO5/LHW activity remain unknown. Here, using a forward genetics approach to identify new factors of the TMO5/LHW pathway, we discovered a novel function of the MYB-type transcription factor, MYB12. MYB12 physically interacts with TMO5 and dampens the TMO5/LHW-mediated induction of direct target gene expression, as well as the periclinal/radial cell divisions. The expression of MYB12 is activated by the cytokinin response, downstream of TMO5/LHW, resulting in a novel MYB12-mediated negative feedback loop that restricts TMO5/LHW activity, to ensure optimal cell proliferation rates during root vascular development. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants

Author

Dragwidge, Jonathan Michael, primary, Wang, Yanning, additional, Brocard, Lysiane, additional, Meyer, Andreas De, additional, Hudeček, Roman, additional, Eeckhout, Dominique, additional, Grones, Peter, additional, Buridan, Matthieu, additional, Chambaud, Clément, additional, Pejchar, Přemysl, additional, Potocký, Martin, additional, Winkler, Joanna, additional, Vandorpe, Michael, additional, Serre, Nelson, additional, Fendrych, Matyáš, additional, Bernard, Amelie, additional, Jaeger, Geert De, additional, Pleskot, Roman, additional, Fang, Xiaofeng, additional, and Damme, Daniël Van, additional

Published
2022
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14. Adaptor protein complex interaction map in Arabidopsisidentifies P34 as a common stability regulator

Author

Wang, Peng, Siao, Wei, Zhao, Xiuyang, Arora, Deepanksha, Wang, Ren, Eeckhout, Dominique, Van Leene, Jelle, Kumar, Rahul, Houbaert, Anaxi, De Winne, Nancy, Mylle, Evelien, Vandorpe, Michael, Korver, Ruud A., Testerink, Christa, Gevaert, Kris, Vanneste, Steffen, De Jaeger, Geert, Van Damme, Daniël, and Russinova, Eugenia

Abstract

Adaptor protein (AP) complexes are evolutionarily conserved vesicle transport regulators that recruit coat proteins, membrane cargoes and coated vesicle accessory proteins. As in plants endocytic and post-Golgi trafficking intersect at the trans-Golgi network, unique mechanisms for sorting cargoes of overlapping vesicular routes are anticipated. The plant AP complexes are part of the sorting machinery, but despite some functional information, their cargoes, accessory proteins and regulation remain largely unknown. Here, by means of various proteomics approaches, we generated the overall interactome of the five AP and the TPLATE complexes in Arabidopsis thaliana. The interactome converged on a number of hub proteins, including the thus far unknown adaptin binding-like protein, designated P34. P34 interacted with the clathrin-associated AP complexes, controlled their stability and, subsequently, influenced clathrin-mediated endocytosis and various post-Golgi trafficking routes. Altogether, the AP interactome network offers substantial resources for further discoveries of unknown endomembrane trafficking regulators in plant cells.

Published
2023
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15. Molecular architecture of the endocytic TPLATE complex

Author

Yperman, Klaas, Wang, Jie, Eeckhout, Dominique, Winkler, Joanna, Vu, Lam Dai, Vandorpe, Michael, Grones, Peter, Mylle, Evelien, Kraus, Michael, Merceron, Romain, Nolf, Jonah, Mor, Eliana, de Bruyn, Pieter, Loris, Remy, Potocký, Martin, Savvides, Savvas N., de Rybel, Bert, de Jaeger, Geert, van Damme, Daniël, Pleskot, Roman, Yperman, Klaas, Wang, Jie, Eeckhout, Dominique, Winkler, Joanna, Vu, Lam Dai, Vandorpe, Michael, Grones, Peter, Mylle, Evelien, Kraus, Michael, Merceron, Romain, Nolf, Jonah, Mor, Eliana, de Bruyn, Pieter, Loris, Remy, Potocký, Martin, Savvides, Savvas N., de Rybel, Bert, de Jaeger, Geert, van Damme, Daniël, and Pleskot, Roman

Abstract

Eukaryotic cells rely on endocytosis to regulate their plasma membrane proteome and lipidome. Most eukaryotic groups, except fungi and animals, have retained the evolutionary ancient TSET complex as an endocytic regulator. Unlike other coatomer complexes, structural insight into TSET is lacking. Here, we reveal the molecular architecture of plant TSET [TPLATE complex (TPC)] using an integrative structural approach. We identify crucial roles for specific TSET subunits in complex assembly and membrane interaction. Our data therefore generate fresh insight into the differences between the hexameric TSET in Dictyostelium and the octameric TPC in plants. Structural elucidation of this ancient adaptor complex represents the missing piece in the coatomer puzzle and vastly advances our functional as well as evolutionary insight into the process of endocytosis.

Published
2021

16. Molecular architecture of the endocytic TPLATE complex

Author

Yperman, Klaas, primary, Wang, Jie, additional, Eeckhout, Dominique, additional, Winkler, Joanna, additional, Vu, Lam Dai, additional, Vandorpe, Michael, additional, Grones, Peter, additional, Mylle, Evelien, additional, Kraus, Michael, additional, Merceron, Romain, additional, Nolf, Jonah, additional, Mor, Eliana, additional, De Bruyn, Pieter, additional, Loris, Remy, additional, Potocký, Martin, additional, Savvides, Savvas N., additional, De Rybel, Bert, additional, De Jaeger, Geert, additional, Van Damme, Daniël, additional, and Pleskot, Roman, additional

Published
2021
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17. The TPLATE subunit is essential for structural assembly of the endocytic TSET complex

Author

Yperman, Klaas, primary, Wang, Jie, additional, Eeckhout, Dominique, additional, Winkler, Joanna, additional, Vu, Lam Dai, additional, Vandorpe, Michael, additional, Grones, Peter, additional, Mylle, Evelien, additional, Kraus, Michael, additional, Merceron, Romain, additional, Nolf, Jonah, additional, Mor, Eliana, additional, De Bruyn, Pieter, additional, Loris, Remy, additional, Potocký, Martin, additional, Savvides, Savvas N., additional, De Rybel, Bert, additional, De Jaeger, Geert, additional, Van Damme, Daniel, additional, and Pleskot, Roman, additional

Published
2020
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19. Activation of auxin signalling counteracts photorespiratory H2O2-dependent cell death.

Author

KERCHEV, PAVEL, MÜHLENBOCK, PER, DENECKER, JORDI, MORREEL, KRIS, HOEBERICHTS, FRANK A., VAN DER KELEN, KATRIEN, VANDORPE, MICHAEL, NGUYEN, LONG, AUDENAERT, DOMINIQUE, and VAN BREUSEGEM, FRANK

Subjects
AUXIN, PLANT cellular signal transduction, PHOTOSYNTHESIS, CELL death, PHYSIOLOGICAL effects of hydrogen peroxide, METABOLIC flux analysis, PLANTS
Abstract

The high metabolic flux through photorespiration constitutes a significant part of the carbon cycle. Although the major enzymatic steps of the photorespiratory pathway are well characterized, little information is available on the functional significance of photorespiration beyond carbon recycling. Particularly important in this respect is the peroxisomal catalase activity which removes photorespiratory H2O2 generated during the oxidation of glycolate to glyoxylate, thus maintaining the cellular redox homeostasis governing the perception, integration and execution of stress responses. By performing a chemical screen, we identified 34 small molecules that alleviate the negative effects of photorespiration in Arabidopsis thaliana mutants lacking photorespiratory catalase ( cat2). The chlorophyll fluorescence parameter photosystem II maximum efficiency ( Fv′/ Fm′) was used as a high-throughput readout. The most potent chemical that could rescue the photorespiratory phenotype of cat2 is a pro-auxin that contains a synthetic auxin-like substructure belonging to the phenoxy herbicide family, which can be released in planta. The naturally occurring indole-3-acetic acid ( IAA) and other chemically distinct synthetic auxins also inhibited the photorespiratory-dependent cell death in cat2 mutants, implying a role for auxin signalling in stress tolerance. [ABSTRACT FROM AUTHOR]

Published
2015
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