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3 results on '"Van Zy, Gert U."'

1. HIV-1 drug resistance mutations : Potential applications for point-of-care Genotypic resistance testing

Author

Rhee, Soo Yon, Jordan, Michael R., Raizes, Elliot, Chua, Arlene, Parkin, Neil, Kantor, Rami, Van Zy, Gert U., Mukui, Irene, Hosseinipour, Mina C., Frenkel, Lisa M., Ndembi, Nicaise, Hamers, Raph L., De Wit, Tobias F Rinke, Wallis, Carole L., Gupta, Ravindra K., Fokam, Joseph, Zeh, Clement, Schapiro, Jonathan M., Carmona, Sergio, Katzenstein, David, Tang, Michele, Aghokeng, Avelin F., De Oliveira, Tulio, Wensing, Annemarie M J, Gallant, Joel E., Wainberg, Mark A., Richman, Douglas D., Fitzgibbon, Joseph E., Schito, Marco, Bertagnolio, Silvia, Yang, Chunfu, Shafer, Robert W., Rhee, Soo Yon, Jordan, Michael R., Raizes, Elliot, Chua, Arlene, Parkin, Neil, Kantor, Rami, Van Zy, Gert U., Mukui, Irene, Hosseinipour, Mina C., Frenkel, Lisa M., Ndembi, Nicaise, Hamers, Raph L., De Wit, Tobias F Rinke, Wallis, Carole L., Gupta, Ravindra K., Fokam, Joseph, Zeh, Clement, Schapiro, Jonathan M., Carmona, Sergio, Katzenstein, David, Tang, Michele, Aghokeng, Avelin F., De Oliveira, Tulio, Wensing, Annemarie M J, Gallant, Joel E., Wainberg, Mark A., Richman, Douglas D., Fitzgibbon, Joseph E., Schito, Marco, Bertagnolio, Silvia, Yang, Chunfu, and Shafer, Robert W.

Published
2015

2. HIV-1 drug resistance mutations: Potential applications for point-of-care Genotypic resistance testing

Author

MMB Medische Staf, Infection & Immunity, Rhee, Soo Yon, Jordan, Michael R., Raizes, Elliot, Chua, Arlene, Parkin, Neil, Kantor, Rami, Van Zy, Gert U., Mukui, Irene, Hosseinipour, Mina C., Frenkel, Lisa M., Ndembi, Nicaise, Hamers, Raph L., De Wit, Tobias F Rinke, Wallis, Carole L., Gupta, Ravindra K., Fokam, Joseph, Zeh, Clement, Schapiro, Jonathan M., Carmona, Sergio, Katzenstein, David, Tang, Michele, Aghokeng, Avelin F., De Oliveira, Tulio, Wensing, Annemarie M J, Gallant, Joel E., Wainberg, Mark A., Richman, Douglas D., Fitzgibbon, Joseph E., Schito, Marco, Bertagnolio, Silvia, Yang, Chunfu, Shafer, Robert W., MMB Medische Staf, Infection & Immunity, Rhee, Soo Yon, Jordan, Michael R., Raizes, Elliot, Chua, Arlene, Parkin, Neil, Kantor, Rami, Van Zy, Gert U., Mukui, Irene, Hosseinipour, Mina C., Frenkel, Lisa M., Ndembi, Nicaise, Hamers, Raph L., De Wit, Tobias F Rinke, Wallis, Carole L., Gupta, Ravindra K., Fokam, Joseph, Zeh, Clement, Schapiro, Jonathan M., Carmona, Sergio, Katzenstein, David, Tang, Michele, Aghokeng, Avelin F., De Oliveira, Tulio, Wensing, Annemarie M J, Gallant, Joel E., Wainberg, Mark A., Richman, Douglas D., Fitzgibbon, Joseph E., Schito, Marco, Bertagnolio, Silvia, Yang, Chunfu, and Shafer, Robert W.

Published
2015

3. Early Antiretroviral Therapy in South African Children Reduces HIV-1-Infected Cells and Cell- Associated HIV-1 RNA in Blood Mononuclear Cells.

Author

van Zy, Gert U., Bedison, Margaret A., van Rensburg, Anita Janse, Laughton, Barbara, Cotton, Mark F., and Mellors, John W.

Subjects
*HIV infections, *THERAPEUTICS, *ANTIRETROVIRAL agents, *COMBINATION drug therapy, *SOUTH Africans, *JUVENILE diseases, *COHORT analysis, *DISEASES
Abstract

We measured cell-associated human immunodeficiency virus (HIV)-1 DNA (CAD) and RNA (CAR) and plasma HIV-1 RNA in blood samples from 20 children in the Children with HIV Early Antiretroviral (CHER) cohort after 7-8 years of suppressive combination antiretroviral therapy (cART). Children who initiated cART early (<2 months; n = 12) had lower HIV-1 CAD (median, 48 vs 216; P < .01) and CAR (median, 5 vs 436; P < .01) per million peripheral blood mononuclear cells than children who started later (≥2 months; n = 8). Plasma HIV-1 RNA levels were not significantly lower in early-treated children (0.5 vs 1.2 copies/mL; P = .16). Early treatment at <2 months of age reduces the number of HIV-infected cells and HIV CAR. [ABSTRACT FROM AUTHOR]

Published
2015
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