96 results on '"Van Rossem C"'
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2. Appendix
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van Rossem, C. C., Leeuwenburgh, M. M. N., Heineman, E., editor, Heineman, D.J., editor, Lange jr., J.F.M., editor, Blankensteijn, J.D., editor, Boermeester, M.A., editor, Borel Rinkes, I.H.M., editor, Klaase, J.M., editor, Schipper, I.B., editor, Schreurs, W.H., editor, and Wijnen, R.M.H., editor
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- 2021
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3. Predictors for interval appendectomy in non-operatively treated complicated appendicitis
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de Jonge, J., Bolmers, M. D. M., Musters, G. D., van Rossem, C. C., Bemelman, W. A., and van Geloven, A. A. W.
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- 2019
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4. Imaging in pediatric appendicitis is key to a low normal appendix percentage: a national audit on the outcome of appendectomy for appendicitis in children
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Bolmers, M. D., van Rossem, C. C., Gorter, R. R., Bemelman, W. A., van Geloven, A. A. W., Heij, H. A., and On behalf of the Snapshot Appendicitis Collaborative Study group
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- 2018
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5. Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial
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Hop, W C, Opmeer, B C, Reitsma, J B, Scholte, R A, Waltmann, E W H, Legemate, D A, Bartelsman, J F, Meijer, D W, de Brouwer, M, van Dalen, J, Durbridge, M, Geerdink, M, Ilbrink, G J, Mehmedovic, S, Middelhoek, P, Di Saverio, Salomone, Boom, M J, Consten, E C J, van der Bilt, J D W, van Olden, G D J, Stam, M A W, Verweij, M S, Busch, O R C, Buskens, C J, El-Massoudi, Y, Kluit, A B, van Rossem, C C, Schijven, M P, Tanis, P J, Unlu, C, Gerhards, M F, Karsten, T M, de Nes, L C, Rijna, H, van Wagensveld, B A, Koffeman, G I, Steller, E P, Tuynman, J B, Bruin, S C, van der Peet, D L, Blanken-Peeters, C F J M, Cense, H A, Jutte, E, Crolla, R M P H, van der Schelling, G P, van Zeeland, M, de Graaf, E J R, Groenendijk, R P R, Vermaas, M, Schouten, O, de Vries, M R, Prins, H A, Lips, D J, Bosker, R J I, van der Hoeven, J A B, Diks, J, Plaisier, P W, Kruyt, P M, Sietses, C, Stommel, M W J, Nienhuijs, S W, de Hingh, I H J T, Luyer, M D P, van Montfort, G, Ponten, E H, Smulders, J F, van Duyn, E B, Klaase, J M, Swank, D J, Ottow, R T, Stockmann, H B A C, Vermeulen, J, Vuylsteke, R J C L M, Belgers, H J, Fransen, S, von Meijenfeldt, E M, Sosef, M N, van Geloven, A A W, Hendriks, E R, ter Horst, B, Leeuwenburgh, M M N, van Ruler, O, Vogten, J M, Vriens, E J C, Westerterp, M, Eijsbouts, Q A J, Bentohami, A, Bijlsma, T S, de Korte, N, Nio, D, Govaert, M J P M, Joosten, J J A, Tollenaar, R A E M, Stassen, L P S, Wiezer, M J, Hazebroek, E J, Smits, A B, van Westreenen, H L, Lange, J F, Brandt, A, Nijboer, W N, Toorenvliet, B R, Weidema, W F, Coene, P P L O, Mannaerts, G H H, den Hartog, D, de Vos, R J, Zengerink, J F, Hoofwijk, A G M, Hulsewé, K W E, Melenhorst, J, Stoot, J H M B, Steup, W H, Huijstee, P J, Merkus, J W S, Wever, J J, Maring, J K, Heisterkamp, J, van Grevenstein, W M U, Vriens, M R, Besselink, M G H, Borel Rinkes, I H M, Witkamp, A J, Slooter, G D, Konsten, J L M, Engel, A F, Pierik, E G J M, Frakking, T G, van Geldere, D, Patijn, G A, D'Hoore, A J L, de Buck van Overstraeten, A, Miserez, M, Terrasson, I, Wolthuis, A, De Blasiis, M G, Vennix, Sandra, Musters, Gijsbert D, Mulder, Irene M, Swank, Hilko A, Consten, Esther C, Belgers, Eric H, van Geloven, Anna A, Gerhards, Michael F, Govaert, Marc J, van Grevenstein, Wilhelmina M, Hoofwijk, Anton G, Kruyt, Philip M, Nienhuijs, Simon W, Boermeester, Marja A, Vermeulen, Jefrey, van Dieren, Susan, Lange, Johan F, and Bemelman, Willem A
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- 2015
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6. Exploring the process when developing a lifestyle intervention in primary care for type 2 diabetes: a longitudinal process evaluation
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Linmans, J.J., van Rossem, C., Knottnerus, J.A., and Spigt, M.
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- 2015
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7. Long-term stoma-related reinterventions after anterior resection for rectal cancer with or without anastomosis: population data from the Dutch snapshot study
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Hazen, S. J. A., Vogel, I., Borstlap, W. A. A., Dekker, J. W. T., Tuynman, J. B., Tanis, P. J., Kusters, M., Deijen, C. L., den Dulk, M., Bonjer, H. J., van de Velde, C. J., Aalbers, A. G. J., Acherman, Y., Algie, G. D., von Geusau, B. Alting, Amelung, F., Aukema, T. S., Bakker, I. S., Bartels, S. A., Basha, S., Bastiaansen, A. J. N. M., Belgers, E., Bleeker, W., Blok, J., Bosker, R. J. I., Bosmans, J. W., Boute, M. C., Bouvy, N. D., Bouwman, H., Brandt-Kerkhof, A., Brinkman, D. J., Bruin, S., Bruns, E. R. J., Burbach, J. P. M., Burger, J. W. A., Buskens, C. J., de Mik, S. M. L., van Duijvendijk, P., Gooszen, J. A. H., Hoogland, P., Lamme, B., Marres, C. C., Musters, G. D., van Rossem, C. C., Schreuder, A. M., Swank, H. A., van beek, S. C., van Westreenen, H. L., Westerduin, E., Surgery, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism, APH - Global Health, APH - Quality of Care, CCA - Cancer biology and immunology, Anatomy and neurosciences, General practice, Obstetrics and gynaecology, VU University medical center, Amsterdam Reproduction & Development (AR&D), Graduate School, CCA - Cancer Treatment and Quality of Life, and AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
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medicine.medical_specialty ,Colorectal cancer ,Anastomosis ,medicine.medical_treatment ,digestive system ,Stoma ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,medicine ,Rectal cancer ,business.industry ,Gastroenterology ,Colostomy ,Permanent stoma ,Anterior resection ,medicine.disease ,digestive system diseases ,Colorectal surgery ,Surgery ,medicine.anatomical_structure ,surgical procedures, operative ,Sphincter ,Hartmann’s procedure ,business ,Cohort study ,Abdominal surgery - Abstract
Item does not contain fulltext BACKGROUND: The aim of this study was to analyze the stoma-related reinterventions, complications and readmissions after an anterior resection for rectal cancer, based on a cross-sectional nationwide cohort study with 3-year follow-up. METHODS: Rectal cancer patients who underwent a resection with either a functional anastomosis, a defunctioned anastomosis, or Hartmann's procedure (HP) with an end colostomy in 2011 in 71 Dutch hospitals were included. The primary outcome was number of stoma-related reinterventions. RESULTS: Of the 2095 patients with rectal cancer, 1400 patients received an anterior resection and were included in this study; 257 received an initially functional anastomosis, 741 a defunctioned anastomosis, and 402 patients a HP. Of the 1400 included patients, 62% were males, 38% were females and the mean age was 67 years (SD 11.1). Following a primary functional anastomosis, 48 (19%) patients received a secondary stoma. Stoma-related complications occurred in six (2%) patients, requiring reintervention in one (0.4%) case. In the defunctioned anastomosis group, stoma-related complications were present in 92 (12%) patients, and required reintervention in 23 (3%) patients, in 10 (1%) of these more than 1 year after initial resection. Stoma-related complications occurred in 92 (23%) patients after a HP, and required reintervention in 39 (10%) patients in 17 (4%) of cases more than 1 year after initial resection. The permanent stoma rate was 11% and 20%, in the functional anastomosis and the defuctioned anastomosis group, respectively. The end colostomy in the HP group was reversed in 4% of cases. CONCLUSIONS: Construction of a stoma after resection for rectal cancer with preservation of the sphincter is accompanied with long-term stoma-related morbidity. Stoma complications are more frequent after a HP. Even after 1 year, a significant number of reinterventions are required.
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- 2022
8. The influence of hospital volume on long-term oncological outcome after rectal cancer surgery
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Jonker, Frederik H. W., Hagemans, Jan A. W., Burger, Jacobus W. A., Verhoef, Cornelis, Borstlap, Wernard A. A., Tanis, Pieter J., Aalbers, A., Acherman, Y., Algie, G. D., Alting von Geusau, B., Amelung, F., Aukema, T. S., Bakker, I. S., Bartels, S. A., Basha, S., Bastiaansen, A. J. N. M., Belgers, E., Bemelman, W. A., Bleeker, W., Blok, J., Bosker, R. J. I., Bosmans, J. W., Boute, M. C., Bouvy, N. D., Bouwman, H., Brandt-Kerkhof, A., Brinkman, D. J., Bruin, S., Bruns, E. R. J., Burbach, J. P. M., Clermonts, S., Coene, P. P. L. O., Compaan, C., Consten, E. C. J., Darbyshire, T., de Mik, S. M. L., de Graaf, E. J. R., de Groot, I., de vos tot Nederveen Cappel, R. J. L., de Wilt, J. H. W., van der Wolde, J., den Boer, F. C., Dekker, J. W. T., Demirkiran, A., Derkx-Hendriksen, M., Dijkstra, F. R., van Duijvendijk, P., Dunker, M. S., Eijsbouts, Q. E., Fabry, H., Ferenschild, F., Foppen, J. W., Furnée, E. J. B., Gerhards, M. F., Gerven, P., Gooszen, J. A. H., Govaert, J. A., Van Grevenstein, W. M. U., Haen, R., Harlaar, J. J., Harst, E., Havenga, K., Heemskerk, J., Heeren, J. F., Heijnen, B., Heres, P., Hoff, C., Hogendoorn, W., Hoogland, P., Huijbers, A., Gooszen, J. A. H., Janssen, P., Jongen, A. C., Karthaus, E. G., Keijzer, A., Ketel, J. M. A., Klaase, J., Kloppenberg, F. W. H., Kool, M. E., Kortekaas, R., Kruyt, P. M., Kuiper, J. T., Lamme, B., Lange, J. F., Lettinga, T., Lips, D. J., Logeman, F., Lutke Holzik, M. F., Madsen, E., Mamound, A., Marres, C. C., Masselink, I., Meerdink, M., Menon, A. G., Mieog, J. S., Mierlo, D., Musters, G. D., Neijenhuis, P. A., Nonner, J., Oostdijk, M., Oosterling, S. J., Paul, P. M. P., Peeters, K. C. M. J. C., Pereboom, I. T. A., Polat, F., Poortman, P., Raber, M., Reiber, B. M. M., Renger, R. J., van Rossem, C. C., Rutten, H. J., Rutten, A., Schaapman, R., Scheer, M., Schoonderwoerd, L., Schouten, N., Schreuder, A. M., Schreurs, W. H., Simkens, G. A., Slooter, G. D., Sluijmer, H. C. E., Smakman, N., Smeenk, R., Snijders, H. S., Sonneveld, D. J. A., Spaansen, B., Spillenaar Bilgen, E. J., Steller, E., Steup, W. H., Steur, C., Stortelder, E., Straatman, J., Swank, H. A., Sietses, C., ten Berge, H. A., ten hoeve, H. G., ter Riele, W. W., Thorensen, I. M., Tip-Pluijm, B., Toorenvliet, B. R., Tseng, L., Tuynman, J. B., van Bastelaar, J., van beek, S. C., van de Ven, A. W. H., van de Weijer, M. A. J., van den Berg, C., van den Bosch, I., van der Bilt, J. D. W., van der Hagen, S. J., van der hul, R., van der Schelling, G., van der Spek, A., van der Wielen, N., van duyn, E., van Eekelen, C., van Essen, J. A., van Gangelt, K., van Geloven, A. A. W., van kessel, C., van Loon, Y. T., van Rijswijk, A., van Rooijen, S. J., van Sprundel, T., van Steensel, L., van Tets, W. F., van Westreenen, H. L., Veltkamp, S., Verhaak, T., Verheijen, P. M., Versluis-Ossenwaarde, L., Vijfhuize, S., Vles, W. J., Voeten, S., Vogelaar, F. J., Vrijland, W. W., Westerduin, E., Westerterp, M. E., Wetzel, M., Wevers, K., Wiering, B., Witjes, A. C., Wouters, M. W., Yauw, S. T. K., Zeestraten, E. C., Zimmerman, D. D., Zwieten, T., and Dutch Snapshot Research Group
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- 2017
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9. Does oncological outcome differ between restorative and nonrestorative low anterior resection in patients with primary rectal cancer?
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Roodbeen, Sapho X., Blok, Robin D., Borstlap, Wernard A., Bemelman, Willem A., Hompes, Roel, Tanis, Pieter J., Aalbers, A. G. J., Acherman, Y., Algie, G. D., Alting von Geusau, B., Amelung, F., Aukema, T. S., Bakker, I. S., Bartels, S. A., Basha, S., Bastiaansen, A. J. N. M., Belgers, E., Bleeker, W., Blok, J., Bosker, R. J. I., Bosmans, J. W., Boute, M. C., Bouvy, N. D., Bouwman, H., Brandt-Kerkhof, A., Brinkman, D. J., Bruin, S., Bruns, E. R. J., Burbach, J. P. M., Burger, J. W. A., Buskens, C. J., Clermonts, S., Coene, P. P. L. O., Compaan, C., Consten, E. C. J., Darbyshire, T., de Mik, S. M. L., van Duijvendijk, P., Gooszen, J. A. H., Hoogland, P., Lamme, B., Marres, C. C., Musters, G. D., van Rossem, C. C., Schreuder, A. M., Swank, H. A., Tuynman, J. B., van Beek, S. C., van Westreenen, H. L., Westerduin, E., Robotics and image-guided minimally-invasive surgery (ROBOTICS), Graduate School, CCA - Cancer Treatment and Quality of Life, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Center of Experimental and Molecular Medicine, Surgery, 02 Surgical specialisms, Tytgat Institute for Liver and Intestinal Research, APH - Personalized Medicine, and APH - Quality of Care
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medicine.medical_specialty ,SURGERY ,Colorectal cancer ,MULTICENTER ,Urology ,Anastomosis ,MESORECTAL EXCISION ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,03 medical and health sciences ,0302 clinical medicine ,rectal surgery ,Medicine ,In patient ,Survival analysis ,Low Anterior Resection ,Neoplasia ,oncological outcome ,business.industry ,Proportional hazards model ,Gastroenterology ,Original Articles ,low anterior resection ,medicine.disease ,Dissection ,030220 oncology & carcinogenesis ,Original Article ,030211 gastroenterology & hepatology ,local recurrence ,Outcome data ,business ,RADIOTHERAPY - Abstract
Contains fulltext : 239366.pdf (Publisher’s version ) (Open Access) AIM: Nonrestorative low anterior resection (n-rLAR) (also known as low Hartmann's) is performed for rectal cancer when a poor functional outcome is anticipated or there have been problems when constructing the anastomosis. Compared with restorative LAR (rLAR), little oncological outcome data are available for n-rLAR. The aim of this study was to compare oncological outcomes between rLAR and n-rLAR for primary rectal cancer. METHOD: This was a nationwide cross-sectional comparative study including all elective sphincter-saving LAR procedures for nonmetastatic primary rectal cancer performed in 2011 in 71 Dutch hospitals. Oncological outcomes of patients undergoing rLAR and n-rLAR were collected in 2015; the data were evaluated using Kaplan-Meier survival analysis and the results compared using log-rank testing. Uni- and multivariable Cox regression analysis was used to evaluate the association between the type of LAR and oncological outcome measures. RESULTS: A total of 1197 patients were analysed, of whom 892 (75%) underwent rLAR and 305 (25%) underwent n-rLAR. The 3-year local recurrence (LR) rate was 3% after rLAR and 8% after n-rLAR (P
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- 2020
10. Prognostic importance of lymph node count and ratio in rectal cancer after neoadjuvant chemoradiotherapy: Results from a cross-sectional study
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Detering, Robin, Meyer, Vincent M., Borstlap, Wernard A. A., Beets-Tan, Regina G. H., Marijnen, Corrie A. M., Hompes, Roel, Tanis, Pieter J., van Westreenen, Henderik L., Aalbers, A. G. J., Acherman, Y., Algie, G. D., Alting von Geusau, B., Amelung, F., Aukema, T. S., Bakker, I. S., Bartels, S. A., Basha, S., Bastiaansen, A. J. N. M., Belgers, E., Bleeker, W., Blok, J., Bosker, R. J. I., Bosmans, J. W., Boute, M. C., Bouvy, N. D., Bouwman, H., Brandt-Kerkhof, A., Brinkman, D. J., Bruin, S., Bruns, E. R. J., Burbach, J. P. M., Burger, J. W. A., Buskens, C. J., Clermonts, S., Coene, P. P. L. O., Compaan, C., de Mik, S. M. L., van Duijvendijk, P., Gooszen, J. A. H., Hoogland, P., Lamme, B., Marres, C. C., Musters, G. D., van Rossem, C. C., Schreuder, A. M., Swank, H. A., Tuynman, J. B., van Beek, S. C., van Westreenen, H. L., Westerduin, E., Surgery, CCA - Cancer Treatment and Quality of Life, Amsterdam Gastroenterology Endocrinology Metabolism, Graduate School, AGEM - Endocrinology, metabolism and nutrition, CCA - Cancer Treatment and quality of life, Anatomy and neurosciences, General practice, VU University medical center, Obstetrics and gynaecology, and Amsterdam Reproduction & Development (AR&D)
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Oncology ,medicine.medical_specialty ,disease-free survival ,Colorectal cancer ,Cross-sectional study ,survival ,chemoradiotherapy ,03 medical and health sciences ,0302 clinical medicine ,lymph nodes ,Internal medicine ,Medicine ,Humans ,Stage (cooking) ,rectal cancer ,Lymph node ,Neoplasm Staging ,Netherlands ,Retrospective Studies ,business.industry ,Rectal Neoplasms ,General Medicine ,medicine.disease ,Prognosis ,Total mesorectal excision ,Neoadjuvant Therapy ,Survival Rate ,medicine.anatomical_structure ,Cross-Sectional Studies ,030220 oncology & carcinogenesis ,Lymphatic Metastasis ,Cohort ,Multivariate Analysis ,030211 gastroenterology & hepatology ,Surgery ,business ,Chemoradiotherapy ,Neoadjuvant chemoradiotherapy - Abstract
Background: The aim of this study was to determine the prognostic value of lymph node count (LNC) and lymph node ratio (LNR) in rectal cancer after neoadjuvant chemoradiotherapy (CRT). Methods: Patients who underwent neoadjuvant CRT and total mesorectal excision (TME) for Stage I–III rectal cancer were selected from a cross-sectional study including 71 Dutch centres. Primary outcome parameters were disease-free survival (DFS) and overall survival (OS). Prognostic significance of LNC and LNR (cut-off values 0.15, 0.20, 0.30) was tested for different (sub)groups. Results: From 2095 registered patients, 458 were included, of which 240 patients with LNC < 12 and 218 patients with LNC ≥ 12. LNC was not significantly associated with DFS (p = 0.35) and OS (p = 0.59). In univariable analysis, LNR was significantly associated with DFS and OS in the whole cohort and LNC subgroups, but not in multivariable analysis. Conclusions: LNC was not associated with long-term oncological outcome in rectal cancer patients treated with CRT, nor was LNR when corrected for N-stage. However, LNR might be used to identify subgroups of node-positive patients with a favourable outcome.
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- 2021
11. Prospective nationwide outcome audit of surgery for suspected acute appendicitis
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van Rossem, C. C., Bolmers, M. D. M., Schreinemacher, M. H. F., van Geloven, A. A. W., Bemelman, W. A., van Acker, G. J. D., Akkermans, B., Akkersdijk, G. J. M., Algie, G. D., Allema, J. H., Andeweg, C. S., Appeldorn, N., van Baal, J. G., den Bakker, C. M., Bartels, S. A. L., van den Berg, C., Boekestijn, B., den Boer, F. C., Boerma, D., van den Boom, A. L., Boute, M. C., Bouwense, S. A. W., Bransen, J., van Brussel, F. A., Busch, O. R. C., de Castro, S. M. M., Cense, H. A., Croese, C., van Dalen, T., Dawson, I., van Dessel, E., Dettmers, R., Dhar, N., Dohmen, F. Y. M., van Dongen, K. W., van Duijvendijk, P., Dulfer, R. R., Dwars, B. J., Eerenberg, J. P., van der Elst, M., van den Ende, E., Fassaert, L. M. M., Fikkers, J. T., Foppen, J. W., Furnee, E. J. B., Garssen, F. P., Gerhards, M. F., van Goor, H., Gorter, R. R., de Graaf, J. S., Graat, L. J., Groote, J., van der Ham, A. C., Hamming, J. F., Hamminga, J. T. H., van der Harst, E., Heemskerk, J., Heij, H. A., Heijne, A., Heikens, J. T., Heineman, E., Hertogs, R., van Heurn, E., van den Hil, L. C. L., Hoofwijk, A. G. M., Hulsker, C. C. C., Hunen, D. R. M., Ibelings, M. S., Klaase, J. M., Klicks, R., Knaapen, L., Kortekaas, R. T. J., Kruyt, F., Kwant, S., Lases, S. S., Lettinga, T., Loupatty, A., Matthijsen, R. A., Minnee, R. C., Mirck, B., Mitalas, L., Moes, D., Moorman, A. M., Nieuwenhuijs, V. B., Nieuwenhuijzen, G. A. P., Nijk, P. D., Omloo, J. M. T., Ottenhof, A. G., Palamba, H. W., van der Peet, D. L., Pereboom, I. T. A., Plaisier, P. W., van der Ploeg, A. P. T., Raber, M. H., Reijnen, M. M. P. J., Rijna, H., Rosman, C., Roumen, R. M. H., Schmitz, R. F., van der Velden, Schouten A. P., Schreurs, W. H., Sigterman, T. A., Smeets, H. J., Sonneveld, D. J. A., Sosef, M. N., Spoor, S. F., Stassen, L. P. S., van Steensel, L., Stortelder, E., Straatman, J., van Susante, H. J., de Hoog, Suykerbuyk D. E. N. M., van Scheltinga, Terwisscha C., Toorenvliet, B. R., Verbeek, B. M., Verbeek, P. C. M., Verseveld, M., Volders, J. H., Vriens, M. R., Vriens, P. W. H. E., Vrouenraets, B. C., van de Wall, B. J. M., Wegdam, J. A., Westerduin, E., Wever, J. J., Wijffels, N. A. T., Wijnhoven, B. P. L., Winkel, T. A., van der Zee, D. C., Zeillemaker, A. M., and Zietse, C.
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- 2016
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12. The impact of stapling technique and surgeon specialism on anastomotic failure after right-sided colorectal resection: an international multicentre, prospective audit
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Glasbey, Jc, Nepogodiev, D, Battersby, N, Bhangu, A, El-Hussuna, A, Frasson, M, Singh, B, Vennix, S, Zmora, O, Pinkney, T, Chaudhri, S, Bemelman, W, Christensen, P, D'Hoore, A, Laurberg, S, Morton, D, Rubbini, M, Vaizey, C, Mehta, S, Ives, N, Magill, L, Perry, R, Sheward, N, Cillo, M, Estefania, D, Patron Uriburu, J, Ruiz, H, Salomon, M, Makhmudov, A, Selnyahina, L, Varabei, A, Vizhynis, Y, Claeys, D, Defoort, B, Muysoms, F, Pletinckx, P, Vergucht, V, Debergh, I, Feryn, T, Reusens, H, Nachtergaele, M, Francart, D, Jehaes, C, Markiewicz, S, Monami, B, Weerts, J, Bouckaert, W, Houben, B, Knol, J, Sergeant, G, Vangertruyden, G, Haeck, L, Lange, C, Sommeling, C, Vindevoghel, K, Castro, S, De Bruyn, H, Huyghe, M, De Wolf, E, Reynders, D, de Buck van Overstraeten, A, Wolthuis, A, Delibegovic, S, Christiani, A, Marchiori, M Jr, Rocha de Moraes, C, Tercioti, V Jr, Arabadjieva, E, Bulanov, D, Dardanov, D, Stoyanov, V, Yonkov, A, Angelov, K, Maslyankov, S, Sokolov, M, Todorov, G, Toshev, S, 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V., Kenic, M., Kovacevic, B., Krdzic, I., Korcek, J., Rems, M., Toplak, J., Escarrâ, J., Gil Barrionuevo, M., Golda, T., Kreisler Moreno, E., Zerpa Martin, C., Álvarez Laso, C., Cumplido, P., Padin, H., Baixauli Fons, J., Hernández-Lizoain, J., Martinez-Ortega, P., Molina-Fernández, M., Sánchez-Justicia, C., Antonio Gracia Solanas, J., Córdoba Díaz de Laspra, E., Echazarreta-Gallego, E., Elia-Guedea, M., Ramirez, J., Arredondo Chaves, J., Diez González, P., Elosua, T., Sahagún, J., Turienzo Frade, A., Álvarez Conde, J., Castrillo, E., Diaz Maag, R., Maderuelo, V., Saldarriaga, L., Aldrey Cao, I., Fernández Varela, X., Núñez Fernández, S., Parajó Calvo, A., Villar Álvarez, S., Blesa Sierra, I., Lozano, R., Márquez, M., Porcel, O., Menendez, P., Fernández Hevia, M., Flores Sigüenza, L., Jimenez Toscano, M., Lacy Fortuny, A., Ordoñez Trujillo, J., Espi, A., Garcia-Botello, S., Martín-Arévalo, J., Moro-Valdezate, D., Pla-Martí, V., Blanco-Antona, F., Abrisqueta, J., Ibañez Canovas, N., Lujan Mompean, J., Escolá Ripoll, D., Martinez Gonzalez, S., Parodi, J., Fernández López, A., Ramos Fernández, M., Castellvi Valls, J., Ortiz de Zarate, L., Ribas, R., Sabia, D., Viso, L., Alonso Gonçalves, S., José Gil Egea, M., Pascual Damieta, M., Pera, M., Salvans Ruiz, S., Bernal, J., Landete, F., Ais, G., Etreros, J., Aguiló Lucia, J., Boscá, A., Deusa, S., García del Caño, J., Viciano, V., García-Armengol, J., Roig, J., Blas, J., Escartin, J., Fatás, J., Fernando, J., Ferrer, R., Arias Pacheco, R., García Flórez, L., Moreno Gijón, M., Otero Díez, J., Solar Garcia, L., Aguilar Teixido, F., Balaguer Ojo, C., Bargallo Berzosa, J., Lamas Moure, S., Enrique Sierra, J., Fermiñán, A., Herrerias, F., Rufas, M., Viñas, J., Codina-Cazador, A., Farrés, R., Gómez, N., Julià, D., Planellas, P., López, J., Luna, A., Maristany, C., Muñoz Duyos, A., Puértolas, N., Alcantara Moral, M., Serra-Aracil, X., Concheiro Coello, P., Gómez, D., Carton, C., Miguel, A., Reoyo Pascual, F., Valero Cerrato, X., Zambrano Muñoz, R., Cervera-Aldama, J., García González, J., Ramos-Prada, J., Santamaría-Olabarrieta, M., Urigüen-Echeverría, A., Coves Alcover, R., Espinosa Soria, J., Fernandez Rodriguez, E., Hernandis Villalba, J., Maturana Ibañez, V., De la Torre Gonzalez, F., Huerga, D., Pérez Viejo, E., Rivera, A., Ruiz Ucar, E., Garcia-Septiem, J., Jiménez, V., Jiménez Miramón, J., Ramons Rodriquez, J., Rodriguez Alvarez, V., Garcea, A., Ponchietti, L., Borda, N., Enriquez-Navascues, J., Saralegui, Y., Febles Molina, G., Nogues, E., Rodríguez Méndez, à ., Roque Castellano, C., Sosa Quesada, Y., Alvarez-Gallego, M., Pascual, I., Rubio-Perez, I., Diaz-San Andrés, B., Tone-Villanueva, F., Alonso, J., Cagigas, C., Castillo, J., Gómez, M., Martín-Parra, J., Mengual Ballester, M., Pellicer Franco, E., Soria Aledo, V., Valero Navarro, G., Caballero Rodríguez, E., Gonzalez De Chaves, P., Hernandez, G., Perez Alvarez, A., Soto Sanchez, A., Cesar Becerra Garcia, F., Guillermo Alonso Roque, J., López Rodríguez Arias, F., Del Valle Ruiz, S. R., Sánchez De La Villa, G., Compañ, A., García Marín, A., Nofuentes, C., Orts Micó, F., Pérez Auladell, V., Carrasco, M., Duque Perez, C., Gálvez-Pastor, S., Navarro Garcia, I., Sanchez Perez, A., Enjuto, D., Manuel Bujalance, F., Marcelin, N., Pérez, M., Serrano García, R., Cabrera, A., de la Portilla, F., Diaz-Pavon, J., Jimenez-Rodriguez, R., Vazquez-Monchul, J., Daza González, J., Gómez Pérez, R., Rivera Castellano, J., Roldán de la Rua, J., Errasti Alustiza, J., Fernandez, L., Romeo Ramirez, J., Sardon Ramos, J., Cermeño Toral, B., Alias, D., Garcia-Olmo, D., Guadalajara, H., Herreros, M., Pacheco, P., del Castillo Díez, F., Lima Pinto, F., Martínez Alegre, J., Ortega, I., Picardo Nieto Antonio, A., Caro, A., Escuder, J., Feliu, F., Millan, M., Alos Company, R., Frangi Caregnato, A., Lozoya Trujillo, R., Rodríguez Carrillo, R., Ruiz Carmona, M., Alonso, N., Ambrona Zafra, D., Amilka Ayala Candia, B., Bonnin Pascual, J., Pineño Flores, C., Alcazar Montero, J., Angoso Clavijo, M., Garcia, J., Sanchez Tocino, J., Gómez-Alcazar, C., Costa-Navarro, D., Ferri-Romero, J., Rey-Riveiro, M., Romero-Simó, M., Arencibia, B., Esclapez, P., García-Granero, E., Granero, P., Medina Fernández, F. J., Gallardo Herrera, A. B., Diaz López, C., Navarro Rodriguez, E., Torres Tordera, E., Arenal, J., Citores, M., Marcos, J., Sánchez, J., Tinoco, C., Espin, E., Garcia Granero, A., Jimenez Gomez, L., Sanchez Garcia, J., Vallribera, F., Folkesson, J., Sköldberg, F., Bergman, K., Borgström, E., Frey, J., Silfverberg, A., Söderholm, M., Nygren, J., Segelman, J., Gustafsson, D., Lagerqvist, A., Papp, A., Pelczar, M., Abraham-Nordling, M., Ahlberg, M., Sjovall, A., Tengstrom, J., Hagman, K., Chabok, A., Ezra, E., Nikberg, M., Smedh, K., Tiselius, C., Al-Naimi, N., Dao Duc, M., Meyer, J., Mormont, M., Ris, F., Prevost, G., Villiger, P., Hoffmann, H., Kettelhack, C., Kirchhoff, P., Oertli, D., Weixler, B., Aytac, B., Leventoglu, S., Mentes, B., Yuksel, O., Demirbas, S., Busra Ozkan, B., Selçuk Özbalci, G., Sungurtekin, U., Gülcü, B., Ozturk, E., Yilmazlar, T., Challand, C., Fearnhead, N., Hubbard, R., Kumar, S., Arthur, J., Barben, C., Skaife, P., Slawik, S., Williams, M., Zammit, M., Barker, J., French, J., Sarantitis, I., Slawinski, C., Clifford, R., Eardley, N., Johnson, M., Mcfaul, C., Vimalachandran, D., Allan, S., Bell, A., Oates, E., Shanmugam, V., Brigic, A., Halls, M., Pucher, P., Stubbs, B., Agarwal, T., Chopada, A., Mallappa, S., Pathmarajah, M., Sugden, C., Brown, C., Macdonald, E., Mckay, A., Richards, J., Robertson, A., Kaushal, M., Patel, P., Tezas, S., Touqan, N., Ayaani, S., Marimuthu, K., Piramanayagam, B., Vourvachis, M., Iqbal, N., Korsgen, S., Seretis, C., Shariff, U., Arnold, S., Chan, H., Clark, E., Fernandes, R., Moran, B., Bajwa, A., Mcarthur, D., Cao, K., Cunha, P., Pardoe, H., Quddus, A., Theodoropoulou, K., Bolln, C., Denys, G., Gillespie, M., Manimaran, N., Reidy, J., Malik, A. I., Malik, A., Pitt, J., Aryal, K., El-Hadi, A., Lal, R., Pal, A., Velchuru, V., Oliveira Cunha, M., Thomas, M., Bains, S., Boyle, K., Miller, A., Norwood, M., Yeung, J., Goian, L., Gurjar, S., Saghir, W., Sengupta, N., Stewart-Parker, E., Bailey, S., Khalil, T., Lawes, D., Nikolaou, S., Omar, G., Church, R., Muthiah, B., Garrett, W., Marsh, P., Obeid, N., Chandler, S., Coyne, P., Evans, M., Hunt, L., Lim, J., Oliphant, Z., Papworth, E., Weaver, H., Cuiñas Leon, K., Williams, G., Hernon, J., Kapur, S., Moosvi, R., Shaikh, I., Swafe, L., Aslam, M., Evans, J., Ihedioha, U., Kang, P., Merchant, J., Hompes, R., Middleton, R., Broomfield, A., Crutten-Wood, D., Foster, J., Nash, G., Akhtar, M., Boshnaq, M., Eldesouky, S., Mangam, S., Rabie, M., Ahmed, J., Khan, J., Ming Goh, N., Shamali, A., Stefan, S., Thompson, C., Amin, A., Docherty, J., Lim, M., Walker, K., Watson, A., Hossack, M., Mackenzie, N., Paraoan, M., Alam, N., Daniels, I., Narang, S., Pathak, S., Smart, N., Al-Qaddo, A., Codd, R., Rutka, O., Bronder, C., Crighton, I., Davies, E., Raymond, T., Bookless, L., Griffiths, B., Plusa, S., Carlson, G., Harrison, R., Lees, N., Mason, C., Quayle, J., Branagan, G., Broadhurst, J., Chave, H., Sleight, S., Awad, F., Cruickshank, N., Joy, H., Boereboom, C., Daliya, P., Dhillon, A., Watson, N., Watson, R., Artioukh, D., Gokul, K., Javed, M., Kong, R., Sutton, J., Faiz, O., Jenkins, I., Leo, C. A., Samaranayake, S. F., Warusavitarne, J., Arya, S., Bhan, C., Mukhtar, H., Oshowo, A., Wilson, J., Duff, S., Fatayer, T., Mbuvi, J., Sharma, A., Cornish, J., Davies, L., Harries, R., Morris, C., Torkington, J., Knight, J., Lai, C., Shihab, O., Tzivanakis, A., Hussain, A., Luke, D., Padwick, R., Torrance, A., Tsiamis, A., Dawson, P., Balfour, A., Brady, R., Mander, J., Paterson, H., Chandratreya, N., Chu, H., Cutting, J., Vernon, S., Wai Ho, C., Andreani, S., Patel, H., Warner, M., Yan Qi Tan, J., Iqbal, A., Khan, A., Perrin, K., Raza, A., Tan, S., Meyer, Jérémy, Graduate School, TOBB ETÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, TOBB ETU, Faculty of Medicine, Department of Surgical Sciences, and Demirbaş, Sezai
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Crohn’s disease ,Male ,Leak ,Surgi-cal technique ,anastomotic leak ,Bowel anastomosis ,colorectal cancer ,Crohn's disease ,epidemiology ,international ,oversewn ,stapler ,surgery ,surgical technique ,Colorectal cancer ,medicine.medical_treatment ,030230 surgery ,Colon/surgery ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Epidemiology ,Prospective Studies ,Treatment Failure ,Young adult ,Prospective cohort study ,Colectomy ,Aged, 80 and over ,General Surgery/statistics & numerical data ,Medical Audit ,ddc:617 ,Anastomosis, Surgical ,Gastroenterology ,Middle Aged ,Colorectal Neoplasms/surgery ,Colorectal surgery ,030220 oncology & carcinogenesis ,Female ,Colectomy/adverse effects ,Colorectal Neoplasms ,Anastomotic Leak/etiology ,Adult ,medicine.medical_specialty ,Adolescent ,Colon ,bowel anastomosis ,Colorectal Surgery/statistics & numerical data ,Anastomosis ,NO ,Young Adult ,03 medical and health sciences ,Surgical Stapling ,medicine ,Humans ,Aged ,ta3126 ,business.industry ,Anastomosis, Surgical/adverse effects ,Surgical Stapling/adverse effects ,Bowel anastomosi ,medicine.disease ,Surgery ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,General Surgery ,business ,Colorectal Surgery - Abstract
AIM: There is little evidence to support choice of technique and configuration for stapled anastomoses after right hemicolectomy and ileocaecal resection. This study aimed to determine the relationship between stapling technique and anastomotic failure.METHOD: Any unit performing gastrointestinal surgery was invited to contribute data on consecutive adult patients undergoing right hemicolectomy or ileocolic resection to this prospective, observational, international, multicentre study. Patients undergoing stapled, side-to-side ileocolic anastomoses were identified and multilevel, multivariable logistic regression analyses were performed to explore factors associated with anastomotic leak.RESULTS: One thousand three hundred and forty-seven patients were included from 200 centres in 32 countries. The overall anastomotic leak rate was 8.3%. Upon multivariate analysis there was no difference in leak rate with use of a cutting stapler for apical closure compared with a noncutting stapler (8.4% vs 8.0%, OR 0.91, 95% CI 0.54-1.53, P = 0.72). Oversewing of the apical staple line, whether in the cutting group (7.9% vs 9.7%, OR 0.87, 95% CI 0.52-1.46, P = 0.60) or noncutting group (8.9% vs 5.7%, OR 1.40, 95% CI 0.46-4.23, P = 0.55) also conferred no benefit in terms of reducing leak rates. Surgeons reporting to be general surgeons had a significantly higher leak rate than those reporting to be colorectal surgeons (12.1% vs 7.3%, OR 1.65, 95% CI 1.04-2.64, P = 0.04).CONCLUSION: This study did not identify any difference in anastomotic leak rates according to the type of stapling device used to close the apical aspect. In addition, oversewing of the anastomotic staple lines appears to confer no benefit in terms of reducing leak rates. Although general surgeons operated on patients with more high-risk characteristics than colorectal surgeons, a higher leak rate for general surgeons which remained after risk adjustment needs further exploration.
- Published
- 2018
13. Scoring system to distinguish uncomplicated from complicated acute appendicitis
- Author
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Atema, J. J., van Rossem, C. C., Leeuwenburgh, M. M., Stoker, J., and Boermeester, M. A.
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- 2015
- Full Text
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14. Normal inflammatory markers and acute appendicitis: a national multicentre prospective cohort analysis
- Author
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de Jonge, J., Scheijmans, J. C. G., van Rossem, C. C., van Geloven, A. A. W., Boermeester, M. A., Bemelman, W. A., van Acker, G. J., Akkermans, B., Akkersdijk, G. J., Algie, G. D., Allema, J. H., Andeweg, C. S., Appeldoorn, N., van Baal, J. G., den Bakker, C. M., Bartels, S. A., van den Berg, C., Boekestijn, B., den Boer, F. C., Boerma, D., van den Boom, A. L., Boute, M. C., Bouwense, S. A., Bransen, J., van Brussel, F. A., Busch, O. R., de Castro, S. M., Cense, H. A., Croese, C., van Dalen, T., Dawson, I., van Dessel, E., Dettmers, R., Dhar, N., Dohmen, F. Y., van Dongen, K. W., van Duijvendijk, P., Dulfer, R. R., Dwars, B. J., Eerenberg, J. P., van der Elst, M., van den Ende, E., Fassaert, L. M., Groot, J., van Heurn, E., Lases, S. S., Mirck, B., van der Peet, D. L., Terwisscha van Scheltinga, C., Westerduin, E., Graduate School, Surgery, AII - Inflammatory diseases, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Surgery, and ARD - Amsterdam Reproduction and Development
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Adult ,medicine.medical_specialty ,Inflammatory markers ,Peritonitis ,030230 surgery ,Gastroenterology ,Sensitivity and Specificity ,C-reactive protein ,Cohort Studies ,03 medical and health sciences ,Leukocyte Count ,0302 clinical medicine ,Internal medicine ,White blood cell ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Retrospective Studies ,Complicated appendicitis ,biology ,business.industry ,Incidence (epidemiology) ,Hepatology ,medicine.disease ,Appendicitis ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Acute Disease ,biology.protein ,Original Article ,business ,Biomarkers ,Cohort study - Abstract
Purpose For the diagnosis of acute appendicitis, the combination of clinical and laboratory variables achieves high diagnostic accuracy. Nevertheless, appendicitis can present with normal laboratory tests of inflammation. The aim of this study was to investigate the incidence of normal inflammatory markers in patients operated for acute appendicitis. Methods This is an analysis of data from a prospective, multicentre SNAPSHOT cohort study of patients with suspected acute appendicitis. Only patients with histopathologically proven acute appendicitis were included. Adult patients with acute appendicitis and normal preoperative inflammatory markers were explored further in terms of abdominal complaints, preoperative imaging results and intraoperative assessment of the degree of inflammation and compared to those with elevated inflammatory markers. Results Between June and July 2014, 1303 adult patients with histopathologically proven acute appendicitis were included. In only 23 of 1303 patients (1.8%) with proven appendicitis, both preoperative white blood cell count and C-reactive protein levels were normal. Migration of pain was reported less frequently in patients with normal inflammatory markers compared to those with elevated inflammatory marker levels (17.4% versus 43.0%, p = 0.01). Characteristics like fever, duration of symptoms and localized peritonitis were comparable. Only 4 patients with normal inflammatory markers (0.3% overall) had complicated appendicitis at histopathological evaluation. Conclusion Combined normal WBC and CRP levels are seen in about 2 per 100 patients with confirmed acute appendicitis and can, although rarely, be found in patients with complicated appendicitis.
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- 2021
15. Messung des Verlangens, Tabak zu Rauchen bei der Rückfall-Prävention in der hausärztlichen Versorgung: explorative Analyse einer randomisierten kontrollierten Studie
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Kotz, D, van Rossem, C, Viechtbauer, W, Spigt, M, van Schayck, OCP, Kotz, D, van Rossem, C, Viechtbauer, W, Spigt, M, and van Schayck, OCP
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- 2021
16. Duration of antibiotic treatment after appendicectomy for acute complicated appendicitis
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van Rossem, C. C., Schreinemacher, M. H. F., Treskes, K., van Hogezand, R. M., and van Geloven, A. A. W.
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- 2014
17. Patients with Crohn's disease have longer post-operative in-hospital stay than patients with colon cancer but no difference in complications' rate
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C, Antonio Gracia Solanas, J, Córdoba Díaz de Laspra, E, Arredondo Chaves, J, Diez González, P, Elosua, T, Sahagún, J, Turienzo Frade, A, Álvarez Conde, J, Castrillo, E, Diaz Maag, R, Maderuelo, V, Saldarriaga, L, Aldrey Cao, I, Fernández Varela, X, Núñez Fernández, S, Parajó Calvo, A, Villar Álvarez, S, Blesa Sierra, I, Lozano, R, Márquez, M, Porcel, O, Menendez, P, Fernández Hevia, M, Flores Sigüenza, L, Jimenez Toscano, M, Lacy Fortuny, A, Ordoñez, J, Espi, A, Garcia Botello, S, Martín Arévalo, J, Moro Valdezate, D, Pla, Martív, Blanco Antona, F, Abrisqueta, J, Ibañez Canovas, N, Lujan Mompean, J, Escolá Ripoll, D, Martinez Gonzalez, S, Parodi, J, Fernández López, A, Ramos Fernández, M, Castellvi Valls, J, Ortiz de Zarate, L, Ribas, R, Sabia, D, Viso, L, Alonso Gonçalves, S, José Gil, M, Pascual Damieta, M, Pera, M, Salvans Ruiz, S, Bernal, J, Landete, F, Ais, G, Etreros, J, Aguiló Lucia, J, Boscá, A, Deusa, S, García del Caño, J, Viciano, V, García Armengol, J, Roig, J, Blas, J, 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Crohn’s disease ,medicine.medical_specialty ,Complications ,Colorectal cancer ,SURGERY ,medicine.medical_treatment ,Bowel resection ,Disease ,Inflammatory bowel disease ,NO ,COLORECTAL-CANCER ,03 medical and health sciences ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,MORBIDITY ,0302 clinical medicine ,Medicine ,Crohn’s disease, Colon cancer, Complications, Length of stay, Bowel resection, Right hemicolectomy ,DIVERTICULAR-DISEASE ,Colon cancer ,Length of stay ,Right hemicolectomy ,colon cancer ,complications ,length of stay ,bowel resection ,right hemicolectomy ,PREOPERATIVE OPTIMIZATION ,RISK ,Crohn's disease ,ddc:617 ,business.industry ,medicine.disease ,3126 Surgery, anesthesiology, intensive care, radiology ,digestive system diseases ,Surgery ,030220 oncology & carcinogenesis ,3121 General medicine, internal medicine and other clinical medicine ,Diverticular disease ,Prospective Study ,030211 gastroenterology & hepatology ,SMOKING ,business ,Complication ,Hospital stay ,INFLAMMATORY-BOWEL-DISEASE - Abstract
BACKGROUND: Right hemicolectomy or ileocecal resection are used to treat benign conditions like Crohn's disease (CD) and malignant ones like colon cancer (CC).AIM: To investigate differences in pre- and peri-operative factors and their impact on post-operative outcome in patients with CC and CD.METHODS: This is a sub-group analysis of the European Society of Coloproctology's prospective, multi-centre snapshot audit. Adult patients with CC and CD undergoing right hemicolectomy or ileocecal resection were included. Primary outcome measure was 30-d post-operative complications. Secondary outcome measures were post-operative length of stay (LOS) at and readmission.RESULTS: Three hundred and seventy-five patients with CD and 2,515 patients with CC were included. Patients with CD were younger (median = 37 years for CD and 71 years for CC (P < 0.01), had lower American Society of Anesthesiology score (ASA) grade (P < 0.01) and less comorbidity (P < 0.01), but were more likely to be current smokers (P < 0.01). Patients with CD were more frequently operated on by colorectal surgeons (P < 0.01) and frequently underwent ileocecal resection (P < 0.01) with higher rate of de-functioning/primary stoma construction (P < 0.01). Thirty-day post-operative mortality occurred exclusively in the CC group (66/2515, 2.3%). In multivariate analyses, the risk of post-operative complications was similar in the two groups (OR 0.80, 95%CI: 0.54-1.17; P = 0.25). Patients with CD had a significantly longer LOS (Geometric mean 0.87, 95%CI: 0.79-0.95; P < 0.01). There was no difference in re-admission rates. The audit did not collect data on post-operative enhanced recovery protocols that are implemented in the different participating centers.CONCLUSION: Patients with CD were younger, with lower ASA grade, less comorbidity, operated on by experienced surgeons and underwent less radical resection but had a longer LOS than patients with CC although complications' rate was not different between the two groups.
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- 2019
18. Appendicular neoplasms and consequences in patients undergoing surgery for suspected acute appendicitis
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Bolmers, M. D. M., de Jonge, J., van Rossem, C. C., van Geloven, A. A. W., Bemelman, W. A., van Acker, G. J., Akkermans, B., Akkersdijk, G. J., Algie, G. D., Allema, J. H., Andeweg, C. S., Appeldoorn, N., van Baal, J. G., den Bakker, C. M., Bartels, S. A., van den Berg, C., Boekestijn, B., den Boer, F. C., Boerma, D., van den Boom, A. L., Boute, M. C., Bouwense, S. A., Bransen, J., van Brussel, F. A., Busch, O. R., de Castro, S. M., Cense, H. A., Croese, C., van Dalen, T., Dawson, I., van Dessel, E., Dettmers, R., Dhar, N., Dohmen, F. Y., van Dongen, K. W., van Duijvendijk, P., Dulfer, R. R., Dwars, B. J., Eerenberg, J. P., van der Elst, M., van den Ende, E., Fassaert, L. M., Fikkers, J. T., Foppen, J. W., van Heurn, E., Lases, S. S., Mirck, B., van der Peet, D. L., Terwisscha van Scheltinga, C., Westerduin, E., Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Surgery, and Amsterdam Reproduction & Development (AR&D)
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medicine.medical_specialty ,Neuroendocrine tumors ,Appendix ,Malignancy ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,Internal medicine ,medicine ,Appendectomy ,Humans ,Neoplasm ,Prospective Studies ,Acute appendicitis ,business.industry ,Incidence (epidemiology) ,Gastroenterology ,Hepatology ,Appendicitis ,medicine.disease ,musculoskeletal system ,Surgery ,Neuroendocrine Tumors ,medicine.anatomical_structure ,Acute Disease ,embryonic structures ,Laparoscopy ,Original Article ,business ,Neuroendocrine tumors (NET) ,Cohort study - Abstract
Introduction In patients treated with an appendectomy for acute appendicitis, the specimen is generally sent for histological evaluation. In an era of increasing non-operative treatment for acute appendicitis, it is important to know the incidence, the diagnostic accuracy, and treatment consequences of appendicular neoplasms that are found in acute appendicitis. We hypothesize that pre- and intra-operative parameters might predict an appendicular neoplasm. Methods Data was used from our previous prospective observational cohort study. All patients undergoing surgery for suspected acute appendicitis were included. The primary outcome was the incidence of appendicular neoplasms in patients operated for acute appendicitis. Secondary outcomes were pre-operative diagnostics and imaging outcomes, intra-operative surgical judgment, and postoperative management and outcome. Possible predictors of an appendicular neoplasm were identified and used in multivariable logistic regression. Patients with an appendicular neoplasm were followed for 3 years after initial appendectomy. Results A total of 1975 patients underwent surgery for suspected acute appendicitis and in 98.3% (1941/1975) the appendix was removed. In 1.5% (30/1941) of these patients, an appendicular neoplasm was found. Among the malignant neoplasms, the majority were grade 1 neuroendocrine tumors (NET) in 65% (13/20). On pre-operative imaging, there was no suspicion of malignancy. In three cases, there was an intra-operative suspicion of malignancy. Multivariable analysis showed only age as an independent predictor for appendicular neoplasms. No recurrent or new malignancy was found during follow-up. Discussion The incidence of appendicular neoplasm in patients undergoing an acute appendectomy is very low and clinical risk factors could not be identified.
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- 2020
19. Acute appendicitis Behandeling volgens de nieuwe richtlijn
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Bom, W. J., Knaapen, M., Gorter, R. R., van Rossem, C. C., Paediatric Surgery, Amsterdam Reproduction & Development (AR&D), and Amsterdam Gastroenterology Endocrinology Metabolism
- Abstract
In this clinical lesson we present two patient cases. A 66-year-old female patient with a clinical, biochemical and radiological suspicion of complex appendicitis. The patient undergoes an appendectomy and post-operative recovery is beset with complications. The other case involves a 24-year-old male patient with suspected simple appendicitis. He is successfully treated with antibiotics and without surgery. By using these patients as examples, we discuss the revised clinical guideline for diagnosing and treating acute appendicitis. Besides that, we also discuss the differentiation between simple and complex appendicitis and how this can influence the treatment plan.
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- 2020
20. Herziene richtlijn over acute appendicitis Aanpassingen in diagnostiek en behandeling
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Bom, W. J., Knaapen, M., Gorter, R. R., van Rossem, C. C., Paediatric Surgery, Amsterdam Reproduction & Development (AR&D), and Amsterdam Gastroenterology Endocrinology Metabolism
- Abstract
Recently, the revised guideline 'Guideline for diagnostics and treatment of acute appendicitis' was published by the Dutch Surgical Society. A patient with limited clinical symptoms and low suspicion of appendicitis can be assessed again at a later time, during which ultrasound diagnostics can be repeated. Following an inconclusive ultrasound scan in children who possibly have appendicitis, it is no longer recommended to perform diagnostic laparoscopy; rather, MRI diagnostics are indicated. In young adults with possible appendicitis, in whom a diagnosis cannot be established using ultrasound, the advice is to use MRI diagnostics instead of CT imaging; this particularly applies to women of child-bearing age. For patients with appendicitis an appendectomy remains the recommended treatment, although one can consider treating adults with suspected simple appendicitis with antibiotics alone. It is important that this decision is made in consultation with the patient. Laparoscopic appendectomy reduces the number of wound infections and admission length, and is therefore usually preferred over open method appendectomy. If a patient with appendicitis is 24-28 weeks pregnant,consultation with a specialist centre is indicated regarding the obstetric management and possibly referral.
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- 2020
21. Predictors for Anastomotic Leak, Postoperative Complications, and Mortality After Right Colectomy for Cancer: Results From an International Snapshot Audit
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Gallo, G., Pata, F., Vennix, S., Laurberg, S., Morton, D., Rubbini, M., Vaizey, C., Magill, L., Perry, R., Sheward, N., Hervas, D., Cillo, M., Estefania, D., Uriburu, J.P., Ruiz, H., Solomon, M., Makhmudov, A., Selnyahina, L., Varabei, A., Vizhynis, Y., Claeys, D., Defoort, B., Muysoms, F., Pletinckx, P., Vergucht, V., Debergh, I., Feryn, T., Reusens, H., Nachtergaele, M., Francart, D., Jehaes, C., Markiewicz, S., Monami, B., Weerts, J., Houben, B., Haeck, L., Lange, C., Sommeling, C., Vindevoghel, K., Castro, S., De Bruyn, H., Huyghe, M., De Wolf, E., Reynders, D., D'Hoore, A., De Buck Van Overstraeten, A., Wolthuis, A., Delibegovic, S., Christiani, A., Marchiori, M., Jr., De Moraes, C.R., Tercioti, V., Jr., Arabadjieva, E., Bulanov, D., Dardanov, D., Stoyanov, V., Yonkov, A., Angelov, K., Maslyankov, S., Sokolov, M., Todorov, G., Toshev, S., Georgiev, Y., Karashmalakov, A., Zafirov, G., Wang, X., Condic, D., Kraljik, D., Mrkovic, H., Pavkovic, V., Raguž, K., Bencurik, V., Holášková, 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B., Garrett, W., Marsh, P., Obeid, N., Chandler, S., Coyne, P., Evans, M., Hunt, L., Lim, J., Oliphant, Z., Papworth, E., Weaver, H., Leon, K.C., Williams, G., Hernon, J., Kapur, S., Moosvi, R., Shaikh, I., Swafe, L., Aslam, M., Evans, J., Ihedioha, U., Kang, P., Merchant, J., Hompes, R., Middleton, R., Broomfield, A., Crutten-Wood, D., Foster, J., Nash, G., Akhtar, M., Boshnaq, M., Eldesouky, S., Mangam, S., Rabie, M., Ahmed, J., Khan, J., Goh, N.M., Shamali, A., Stefan, S., Nepogodiev, D., Pinkney, T.D., Thompson, C., Amin, A., Docherty, J., Lim, M., Walker, K., Watson, A., Hossack, M., Mackenzie, N., Paraoan, M., Alam, N., Daniels, I., Narang, S., Pathak, S., Smart, N., Al-Qaddo, A., Codd, R., Rutka, O., Bronder, C., Crighton, I., Davies, E., Raymond, T., Bookless, L., Griffiths, B., Plusa, S., Carlson, G., Harrison, R., Lees, N., Mason, C., Quayle, J., Branagan, G., Broadhurst, J., Chave, H., Sleight, S., Awad, F., Bhangu, A., Cruickshank, N., Joy, H., Boereboom, C., Daliya, P., Dhillon, A., Watson, N., Watson, R., Artioukh, D., Gokul, K., Javed, M., Kong, R., Sutton, J., Faiz, O., Jenkins, I., Leo, C., Samaranayake, F., Warusavitarne, J., Arya, S., Bhan, C., Mukhtar, H., Oshowo, A., Wilson, J., Duff, S., Fatayer, T., Mbuvi, J., Sharma, A., Cornish, J., Davies, L., Harries, R., Morris, C., Torkington, J., Knight, J., Lai, C., Shihab, O., Tzivanakis, A., Hussain, A., Luke, D., Padwick, R., Torrance, A., Tsiamis, A., Dawson, P., Balfour, A., Brady, R., Mander, J., Paterson, H., Chandratreya, N., Chu, H., Cutting, J., Vernon, S., Ho, C.W., Andreani, S., Patel, H., Warner, M., Tan, J.Y.Q., Iqbal, A., Khan, A., Perrin, K., Raza, A., Tan, S., European Society of Coloproctology Collaborating Group Collaborators, Group, ESCP Cohort Studies Sub-Committee, ESCP Research Committee, Logistical Support and Data Collection, Analysis, Investigators, Radiology and nuclear medicine, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Surgery, MUMC+: MA Heelkunde (9), Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA - Cancer Treatment and Quality of Life, Neurology, and Center for Evidence Based Education
- Subjects
Male ,Leak ,Conference Paper ,adverse event ,ileostomy ,non-smoker ,0302 clinical medicine ,middle aged ,antibiotic therapy ,80 and over ,antibiotic agent ,postoperative complication ,emergency surgery ,Colectomy ,cecum ,Aged, 80 and over ,OUTCOMES ,adult ,COLON-CANCER ,Gastroenterology ,operation duration ,clinical trial ,General Medicine ,cohort analysis ,laparoscopic surgery ,ureter injury ,Survival Rate ,aged ,risk factor ,030220 oncology & carcinogenesis ,Cohort ,kidney injury ,030211 gastroenterology & hepatology ,Colonic Neoplasms/mortality ,anastomosis leakage ,liver injury ,prospective study ,medicine.medical_specialty ,SURGICAL STRESS ,ELECTIVE RIGHT ,surgical infection ,03 medical and health sciences ,Humans ,human ,Aged ,clinical audit ,sex ratio ,major clinical study ,mortality ,hemicolectomy ,multicenter study ,RISK-FACTORS ,observational study ,Complication ,Anastomotic leak ,Colon cancer ,Postoperative outcome ,Right colectomy ,general surgery ,surgical mortality ,SURGERY ,very elderly ,morbidity ,Anastomotic Leak ,mortality rate ,open surgery ,Cohort Studies ,Postoperative Complications ,gallbladder disease ,LAPAROSCOPY ,Risk Factors ,Neoplasms ,cancer mortality ,Laparoscopy ,Prospective cohort study ,colon resection ,Medical Audit ,medicine.diagnostic_test ,Mortality rate ,colon tumor ,Middle Aged ,female ,colon cancer ,Right Colectomy ,Colonic Neoplasms ,ileum ,surgical stapling ,Female ,cancer surgery ,Colectomy/adverse effects ,duodenum injury ,small intestine resection ,RESECTION ,reoperation ,Anastomosis ,NO ,MORBIDITY ,medicine ,operative blood loss ,LS7_4 ,percutaneous drainage ,business.industry ,suture technique ,Surgery ,blood vessel injury ,peroperative complication ,elective surgery ,Anastomotic Leak/epidemiology ,pathology ,business - Abstract
A right hemicolectomy is among the most commonly performed operations for colon cancer, but modern high-quality, multination data addressing the morbidity and mortality rates are lacking.This study reports the morbidity and mortality rates for right-sided colon cancer and identifies predictors for unfavorable short-term outcome after right hemicolectomy.This was a snapshot observational prospective study.The study was conducted as a multicenter international study.The 2015 European Society of Coloproctology snapshot study was a prospective multicenter international series that included all patients undergoing elective or emergency right hemicolectomy or ileocecal resection over a 2-month period in early 2015. This is a subanalysis of the colon cancer cohort of patients.Predictors for anastomotic leak and 30-day postoperative morbidity and mortality were assessed using multivariable mixed-effect logistic regression models after variables selection with the Lasso method.Of the 2515 included patients, an anastomosis was performed in 97.2% (n = 2444), handsewn in 38.5% (n = 940) and stapled in 61.5% (n = 1504) cases. The overall anastomotic leak rate was 7.4% (180/2444), 30-day morbidity was 38.0% (n = 956), and mortality was 2.6% (n = 66). Patients with anastomotic leak had a significantly increased mortality rate (10.6% vs 1.6% no-leak patients; p0.001). At multivariable analysis the following variables were associated with anastomotic leak: longer duration of surgery (OR = 1.007 per min; p = 0.0037), open approach (OR = 1.9; p = 0.0037), and stapled anastomosis (OR = 1.5; p = 0.041).This is an observational study, and therefore selection bias could be present. For this reason, a multivariable logistic regression model was performed, trying to correct possible confounding factors.Anastomotic leak after oncologic right hemicolectomy is a frequent complication, and it is associated with increased mortality. The key contributing surgical factors for anastomotic leak were anastomotic technique, surgical approach, and duration of surgery. See Video Abstract at http://links.lww.com/DCR/B165. PREDICTORES DE FUGA ANASTOMóTICA, COMPLICACIONES POSTOPERATORIAS Y MORTALIDAD DESPUéS DE LA COLECTOMíA DERECHA POR CáNCER: RESULTADOS DE UNA AUDITORíA INTERNACIONAL DE CORTO PLAZO: La hemicolectomía derecha se encuentra entre las operaciones más frecuentemente realizadas para cáncer de colon, pero faltan datos modernos multinacionales de alta calidad, que aborden las tasas de morbilidad y mortalidad.Reportar la tasa de morbilidad y mortalidad para cáncer de colon del lado derecho, e identificar predictores de resultados desfavorables a corto plazo, después de la hemicolectomía derecha.Estudio prospectivo observacional de corto plazo.Estudio multicéntrico internacional.El estudio de corto plazo de la Sociedad Europea de Coloproctología de 2015, fue una serie prospectiva multicéntrica internacional, que incluyó a todos los pacientes sometidos a hemicolectomía derecha electiva, de emergencia o resección ileocecal, por un período de dos meses y a principios de 2015. Este es un subanálisis, cohorte de pacientes con cáncer de colon.Los predictores de fuga anastomótica, morbilidad y mortalidad postoperatorias a los 30 días, se evaluaron usando modelos de regresión logística de efectos multivariables mixtos, después de la selección de variables con el método Lasso.De los 2,515 pacientes incluidos, se realizó una anastomosis en el 97,2% (n = 2,444); sutura manual en 38.5% (n = 940) y por engrapadora en 61.5% (n = 1504) casos. La tasa global de fuga anastomótica fue del 7,4% (180/2,444), morbilidad a los 30 días fue del 38,0% (n = 956) y la mortalidad fue del 2,6% (n = 66). Los pacientes con fuga anastomótica tuvieron una tasa de mortalidad significativamente mayor (10,6% frente al 1,6% de pacientes sin fuga, p0,001). En el análisis multivariable, las siguientes variables se asociaron con la fuga anastomótica: mayor duración de la cirugía (OR 1.007 por minuto, p = 0.0037), abordaje abierto (OR 1.9, p = 0.0037) y anastomosis por engrapadora (OR 1.5, p = 0.041).Este es un estudio observacional y por lo tanto podría estar presente el sesgo de selección. Por esta razón, se realizó un modelo de regresión logística multivariable, tratando de corregir posibles factores de confusión.La fuga anastomótica después de la hemicolectomía derecha oncológica, es una complicación frecuente y asociada a mayor mortalidad. Los factores quirúrgicos clave que contribuyeron a la fuga anastomótica, fueron la técnica anastomótica, abordaje quirúrgico y duración de la cirugía. Consulte Video Resumen en http://links.lww.com/DCR/B165. (Traducción-Dr. Fidel Ruiz Healy).
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- 2020
22. Appendicular neoplasms and consequences in patients undergoing surgery for suspected acute appendicitis
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Bolmers, M D M, de Jonge, J, van Rossem, C C, van Geloven, A A W, Bemelman, W A, Bolmers, M D M, de Jonge, J, van Rossem, C C, van Geloven, A A W, and Bemelman, W A
- Abstract
INTRODUCTION: In patients treated with an appendectomy for acute appendicitis, the specimen is generally sent for histological evaluation. In an era of increasing non-operative treatment for acute appendicitis, it is important to know the incidence, the diagnostic accuracy, and treatment consequences of appendicular neoplasms that are found in acute appendicitis. We hypothesize that pre- and intra-operative parameters might predict an appendicular neoplasm.METHODS: Data was used from our previous prospective observational cohort study. All patients undergoing surgery for suspected acute appendicitis were included. The primary outcome was the incidence of appendicular neoplasms in patients operated for acute appendicitis. Secondary outcomes were pre-operative diagnostics and imaging outcomes, intra-operative surgical judgment, and postoperative management and outcome. Possible predictors of an appendicular neoplasm were identified and used in multivariable logistic regression. Patients with an appendicular neoplasm were followed for 3 years after initial appendectomy.RESULTS: A total of 1975 patients underwent surgery for suspected acute appendicitis and in 98.3% (1941/1975) the appendix was removed. In 1.5% (30/1941) of these patients, an appendicular neoplasm was found. Among the malignant neoplasms, the majority were grade 1 neuroendocrine tumors (NET) in 65% (13/20). On pre-operative imaging, there was no suspicion of malignancy. In three cases, there was an intra-operative suspicion of malignancy. Multivariable analysis showed only age as an independent predictor for appendicular neoplasms. No recurrent or new malignancy was found during follow-up.DISCUSSION: The incidence of appendicular neoplasm in patients undergoing an acute appendectomy is very low and clinical risk factors could not be identified.
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- 2020
23. Discriminating complicated from uncomplicated appendicitis by ultrasound imaging, computed tomography or magnetic resonance imaging: systematic review and meta-analysis of diagnostic accuracy
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Bom, W J, primary, Bolmers, M D, additional, Gans, S L, additional, van Rossem, C C, additional, van Geloven, A A W, additional, Bossuyt, P M M, additional, Stoker, J, additional, and Boermeester, M A, additional
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- 2020
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24. Successful use of fenfluramine as add-on treatment in Dravet syndrome: B3–P1
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CEULEMANS, B, BOEL, M, LEYSSENS, K, VAN ROSSEM, C, NEELS, P, JORENS, P, and LAGAE, L
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- 2012
25. Risk factors for unfavourable postoperative outcome in patients with Crohn's disease undergoing right hemicolectomy or ileocaecal resection. An international audit by ESCP and S-ECCO
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El-Hussuna, A., Pinkney, T., Zmora, O., Frasson, M., Bhangu, A., Battersby, N., Chaudhri, S., Nepogodiev, D., Singh, B., Vennix, S., Altomare, D., Bemelman, W., Christensen, P., D'Hoore, A., Laurberg, S., Morton, D., Rubbini, M., Vaizey, C., Magill, L., Perry, R., Sheward, N., Nørmark Mortensen, Rikke, El-Hussuna, Alaa, Cillo, M., Estefania, D., Patron Uriburu, J., Ruiz, H., Salomon, M., Makhmudov, A., Selnyahina, L., Varabei, A., Vizhynis, Y., Claeys, D., Defoort, B., Muysoms, F., Pletinckx, P., Vergucht, V., Debergh, I., Feryn, T., Reusens, H., Nachtergaele, M., Francart, D., Jehaes, C., Markiewicz, S., Monami, B., Weerts, J., Bouckaert, W., Houben, B., Knol, J., Sergeant, G., Vangertruyden, G., Haeck, L., Lange, C., Sommeling, C., Vindevoghel, K., Castro, S., De Bruyn, H., Huyghe, M., De Wolf, E., Reynders, D., de Buck van Overstraeten, A., Wolthuis, A., Delibegovic, S., Christiani, A., Marchiori, M., Rocha de Moraes, C., Tercioti, V., Arabadjieva, E., Bulanov, D., Dardanov, D., Stoyanov, V., Yonkov, A., Angelov, K., Maslyankov, S., Sokolov, M., Todorov, G., Toshev, S., Georgiev, Y., Karashmalakov, A., Zafirov, G., Wang, X., Condic, D., Kraljik, D., Mrkovic, H., Pavkovic, V., Raguž, K., Bencurik, V., Holášková, E., Skrovina, M., Farkašová, M., Grolich, T., Kala, Z., Antos, F., Pruchova, V., Sotona, O., Chobola, M., Dusek, T., Ferko, A., Örhalmi, J., Hoch, J., Kocian, P., Martinek, L., Bernstein, I., Gotschalck Sunesen, K., Leunbach, J., Thorlacius-Ussing, O., Uth Oveson, A., Dahl Chirstensen, S., Gamez, V., Oeting, M., Schou Loeve, U., Ugianskis, A., Jessen, M., Krarup, P. M., Linde, K., Mirza, Q., Overgaard Stovring, J., Erritzøe, L., Loft Jakobsen, H., Lykke, J., Palmgren Colov, E., Husted Madsen, A., Linde Friis, T., Amstrup Funder, J., Dich, R., Kjær, S., Rasmussen, S., Schlesinger, N., Dilling Kjaer, M., Qvist, N., Khalid, A., Ali, G., Hadi, S., Rosell Walker, L., Kivelä, A., Lehtonen, T., Lepistö, A., Scheinin, T., Siironen, P., Kössi, J., Kuusanmäki, P., Tomminen, T., Turunen, A., Rautio, T., Vierimaa, M., Huhtinen, H., Karvonen, J., Lavonius, M., Rantala, A., Varpe, P., Cotte, E., Francois, Y., Glehen, O., Kepenekian, V., Passot, G., Maggiori, L., Manceau, G., Panis, Y., Gout, M., Rullier, E., van Geluwe, B., Chafai, N., Lefevre, J. 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R., Boccia, L., Gerard, L., Pascariello, A., Manca, G., Marino, F., Casaril, A., Inama, M., Moretto, G., Bacchelli, C., Carvello, M., Mariani, N., Montorsi, M., Spinelli, A., Romairone, E., Scabini, S., Belli, A., Bianco, F., De Franciscis, S., Maria Romano, G., Delrio, P., Pace, U., Rega, D., Sassaroli, C., Scala, D., De Luca, R., Ruggieri, E., Elbetti, C., Garzi, A., Romoli, L., Scatizzi, M., Vannucchi, A., Curletti, G., Durante, V., Galleano, R., Mariani, F., Reggiani, L., Bellomo, R., Infantino, A., Franceschilli, L., Sileri, P., Clementi, I., Coletta, D., La Torre, F., Mingoli, A., Velluti, F., Di Giacomo, A., Fiorot, A., Massani, M., Padoan, L., Ruffolo, C., Caruso, S., Franceschini, F., Laessig, R., Monaci, I., Rontini, M., De Nardi, P., Elmore, U., Lemma, M., Rosati, R., Tamburini, A., De Luca, M., Sartori, A., Benevento, A., Bottini, C., Ferrari, C. C., Pata, F., Tessera, G., Pellino, G., Selvaggi, F., Lanzani, A., Romano, F., Sgroi, G., Steccanella, F., Turati, L., Yamamoto, T., Ancans, G., Gerkis, S., Leja, M., Pcolkins, A., Sivins, A., Latkauskas, T., Lizdenis, P., Saladžinskas, Ž., Švagždys, S., Tamelis, A., Razbadauskas, A., Sokolovas, M., Dulskas, A., Samalavicius, N., Jotautas, V., Mikalauskas, S., Poskus, E., Poskus, T., Strupas, K., Camenzuli, C., Cini, C., Predrag, A., Psaila, J., Spiteri, N., Buskens, C., de Groof, E. J., Gooszen, J., Tanis, P., Belgers, E., Davids, P., Furnee, E., Postma, E., Pronk, A., Smakman, N., Clermonts, S., Zimmerman, D., Omloo, J., van der Zaag, E., van Duijvendijk, P., Wassenaar, E., Bruijninckx, M., de Graff, E., Doornebosch, P., Tetteroo, G., Vermaas, M., Iordens, G., Knops, S., Toorenvliet, B., van Westereenen, H. L., Boerma, E., Coene, P., van der Harst, E., Van Der Pool, A., Raber, M., Melenhorst, J., de Castro, S., Gerhards, M., Arron, M., Bremers, A., de Wilt, H., Ferenschild, F., Yauw, S., Cense, H., Demirkiran, A., Hunfeld, M., Mulder, I., Nonner, J., Swank, H., van Wagensveld, B., Bolmers, M., Briel, J., van Geloven, A., van Rossem, C., Klemann, V., Konsten, J., Leenders, B., Schok, T., Bleeker, W., Gidwani, A., Lawther, R., Loughlin, P., Skelly, B., Spence, R., Brun, M., Helgeland, M., Ignjatovic, D., Øresland, T., Yousefi, P., Flåten Backe, I., Helmer Sjo, O., Nesbakken, A., Tandberg-Eriksen, M., Cais, A., Hallvard Træland, J., Herikstad, R., Kørner, H., Lauvland, N., Jajtner, D., Kabiesz, W., Rak, M., Gmerek, L., Horbacka, K., Horst, N., Krokowicz, P., Kwiatkowski, A., Pasnik, K., Karcz, P., Romaniszyn, M., Rusek, T., Walega, P., Czarencki, R., Obuszko, Z., Sitarska, M., Wojciech, W., Zawadzki, M., Amado, S., Clara, P., Couceiro, A., Malaquias, R., Rama, N., Almeida, A., Barbosa, E., Cernadas, E., Duarte, A., Silva, P., Costa, S., Martinez Insua, C., Pereira, J., Pereira, C., Sacchetti, M., Carvalho Pinto, B., Jorge Vieira Sousa, P., Marques, R., Oliveira, A., Cardoso, R., Carlos, S., Corte-Real, J., Moniz Pereira, P., Souto, R., Carneiro, C., Marinho, R., Nunes, V., Rocha, R., Sousa, M., Leite, J., Melo, F., Pimentel, J., Ventura, L., Vila Nova, C., Copaescu, C., Bintintan, V., Ciuce, C., Dindelegan, G., Scurtu, R., Seicean, R., Domansky, N., Karachun, A., Moiseenko, A., Pelipas, Y., Petrov, A., Pravosudov, I., Aiupov, R., Akmalov, Y., Parfenov, A., Suleymanov, N., Tarasov, N., Jumabaev, H., Mamedli, Z., Rasulov, A., Aliev, I., Chernikovskiy, I., Kochnev, V., Komyak, K., Smirnov, A., Achkasov, S., Bolikhov, K., Shelygin, Y., Sushkov, O., Zapolskiy, A., Gvozdenovic, M., Jovanovic, D., Lausevic, Z., Cvetkovic, D., Maravic, M., Milovanovic, B., Stojakovic, N., Tripkovic, I., Mihajlovic, D., Nestorovic, M., Pecic, V., Petrovic, D., Stanojevic, G., Barisic, G., Dimitrijevic, I., Krivokapic, Z., Markovic, V., Popovic, M., Aleksic, A., Dabic, D., Kostic, I., Milojkovic, A., Perunicic, V., Lukic, D., Petrovic, T., Radovanovic, D., Radovanovic, Z., Cuk, V. 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Rivera, A, Ruiz Ucar, E, Garcia-Septiem, J, Jiménez, V, Jiménez Miramón, J, Ramons Rodriquez, J, Rodriguez Alvarez, V, Garcea, A, Ponchietti, L, Borda, N, Enriquez-Navascues, J, Saralegui, Y, Febles Molina, G, Nogues, E, Rodríguez Méndez, Á, Roque Castellano, C, Sosa Quesada, Y, Alvarez-Gallego, M, Pascual, I, Rubio-Perez, I, Diaz-San Andrés, B, Tone-Villanueva, F, Alonso, J, Cagigas, C, Castillo, J, Gómez, M, Martín-Parra, J, Mengual Ballester, M, Pellicer Franco, E, Soria Aledo, V, Valero Navarro, G, Caballero Rodríguez, E, Gonzalez De Chaves, P, Hernandez, G, Perez Alvarez, A, Soto Sanchez, A, Cesar Becerra Garcia, F, Guillermo Alonso Roque, J, López Rodríguez Arias, F, Del Valle Ruiz, Sr, Sánchez De La Villa, G, Compañ, A, García Marín, A, Nofuentes, C, Orts Micó, F, Pérez Auladell, V, Carrasco, M, Duque Perez, C, Gálvez-Pastor, S, Navarro Garcia, I, Sanchez Perez, A, Enjuto, D, Manuel Bujalance, F, Marcelin, N, Pérez, M, Serrano García, R, Cabrera, A, de la Portilla, F, Diaz-Pavon, J, Jimenez-Rodriguez, R, Vazquez-Monchul, J, Daza González, J, Gómez Pérez, R, Rivera Castellano, J, Roldán de la Rua, J, Errasti Alustiza, J, Fernandez, L, Romeo Ramirez, J, Sardon Ramos, J, Cermeño Toral, B, Alias, D, Garcia-Olmo, D, Guadalajara, H, Herreros, M, Pacheco, P, Del Castillo Díez, F, Lima Pinto, F, Martínez Alegre, J, Ortega, I, Picardo Nieto Antonio, A, Caro, A, Escuder, J, Feliu, F, Millan, M, Alos Company, R, Frangi Caregnato, A, Lozoya Trujillo, R, Rodríguez Carrillo, R, Ruiz Carmona, M, Alonso, N, Ambrona Zafra, D, Amilka Ayala Candia, B, Bonnin Pascual, J, Pineño Flores, C, Alcazar Montero, J, Angoso Clavijo, M, Garcia, J, Sanchez Tocino, J, Gómez-Alcazar, C, Costa-Navarro, D, Ferri-Romero, J, Rey-Riveiro, M, Romero-Simó, M, Arencibia, B, Esclapez, P, García-Granero, E, Granero, P, Medina Fernández, Fj, Gallardo Herrera, Ab, Diaz López, C, Navarro Rodriguez, E, Torres Tordera, E, Arenal, J, Citores, M, Marcos, J, Sánchez, J, Tinoco, C, Espin, E, Garcia Granero, A, Jimenez Gomez, L, Sanchez Garcia, J, Vallribera, F, Folkesson, J, Sköldberg, F, Bergman, K, Borgström, E, Frey, J, Silfverberg, A, Söderholm, M, Nygren, J, Segelman, J, Gustafsson, D, Lagerqvist, A, Papp, A, Pelczar, M, Abraham-Nordling, M, Ahlberg, M, Sjovall, A, Tengstrom, J, Hagman, K, Chabok, A, Ezra, E, Nikberg, M, Smedh, K, Tiselius, C, Al-Naimi, N, Dao Duc, M, Meyer, J, Mormont, M, Ris, F, Prevost, G, Villiger, P, Hoffmann, H, Kettelhack, C, Kirchhoff, P, Oertli, D, Weixler, B, Aytac, B, Leventoglu, S, Mentes, B, Yuksel, O, Demirbas, S, Busra Ozkan, B, Selçuk Özbalci, G, Sungurtekin, U, Gülcü, B, Ozturk, E, Yilmazlar, T, Challand, C, Fearnhead, N, Hubbard, R, Kumar, S, Arthur, J, Barben, C, Skaife, P, Slawik, S, Williams, M, Zammit, M, Barker, J, French, J, Sarantitis, I, Slawinski, C, Clifford, R, Eardley, N, Johnson, M, Mcfaul, C, Vimalachandran, D, Allan, S, Bell, A, Oates, E, Shanmugam, V, Brigic, A, Halls, M, Pucher, P, Stubbs, B, Agarwal, T, Chopada, A, Mallappa, S, Pathmarajah, M, Sugden, C, Brown, C, Macdonald, E, Mckay, A, Richards, J, Robertson, A, Kaushal, M, Patel, P, Tezas, S, Touqan, N, Ayaani, S, Marimuthu, K, Piramanayagam, B, Vourvachis, M, Iqbal, N, Korsgen, S, Seretis, C, Shariff, U, Arnold, S, Chan, H, Clark, E, Fernandes, R, Moran, B, Bajwa, A, Mcarthur, D, Cao, K, Cunha, P, Pardoe, H, Quddus, A, Theodoropoulou, K, Bolln, C, Denys, G, Gillespie, M, Manimaran, N, Reidy, J, Malik, Ai, Malik, A, Pitt, J, Aryal, K, El-Hadi, A, Lal, R, Pal, A, Velchuru, V, Oliveira Cunha, M, Thomas, M, Bains, S, Boyle, K, Miller, A, Norwood, M, Yeung, J, Goian, L, Gurjar, S, Saghir, W, Sengupta, N, Stewart-Parker, E, Bailey, S, Khalil, T, Lawes, D, Nikolaou, S, Omar, G, Church, R, Muthiah, B, Garrett, W, Marsh, P, Obeid, N, Chandler, S, Coyne, P, Evans, M, Hunt, L, Lim, J, Oliphant, Z, Papworth, E, Weaver, H, Cuiñas Leon, K, Williams, G, Hernon, J, Kapur, S, Moosvi, R, Shaikh, I, Swafe, L, Aslam, M, Evans, J, Ihedioha, U, Kang, P, Merchant, J, Hompes, R, Middleton, R, Broomfield, A, Crutten-Wood, D, Foster, J, Nash, G, Akhtar, M, Boshnaq, M, Eldesouky, S, Mangam, S, Rabie, M, Ahmed, J, Khan, J, Ming Goh, N, Shamali, A, Stefan, S, Thompson, C, Amin, A, Docherty, J, Lim, M, Walker, K, Watson, A, Hossack, M, Mackenzie, N, Paraoan, M, Alam, N, Daniels, I, Narang, S, Pathak, S, Smart, N, Al-Qaddo, A, Codd, R, Rutka, O, Bronder, C, Crighton, I, Davies, E, Raymond, T, Bookless, L, Griffiths, B, Plusa, S, Carlson, G, Harrison, R, Lees, N, Mason, C, Quayle, J, Branagan, G, Broadhurst, J, Chave, H, Sleight, S, Awad, F, Cruickshank, N, Joy, H, Boereboom, C, Daliya, P, Dhillon, A, Watson, N, Watson, R, Artioukh, D, Gokul, K, Javed, M, Kong, R, Sutton, J, Faiz, O, Jenkins, I, Leo, Ca, Samaranayake, Sf, Warusavitarne, J, Arya, S, Bhan, C, Mukhtar, H, Oshowo, A, Wilson, J, Duff, S, Fatayer, T, Mbuvi, J, Sharma, A, Cornish, J, Davies, L, Harries, R, Morris, C, Torkington, J, Knight, J, Lai, C, Shihab, O, Tzivanakis, A, Hussain, A, Luke, D, Padwick, R, Torrance, A, Tsiamis, A, Dawson, P, Balfour, A, Brady, R, Mander, J, Paterson, H, Chandratreya, N, Chu, H, Cutting, J, Vernon, S, Wai Ho, C, Andreani, S, Patel, H, Warner, M, Yan Qi Tan, J, Iqbal, A, Khan, A, Perrin, K, Raza, A, Tan, S., and 2015 European Society of Coloproctology collaborating, Group
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creatinine blood level ,adverse event ,Disease ,open surgery ,surgery ,0302 clinical medicine ,hospital readmission ,postoperative complication ,resection ,Crohn's disease ,Resection ,Surgery ,outcome ,parenteral nutrition ,postoperative complications ,C reactive protein ,adult ,Gastroenterology ,creatinine ,Crohn disease ,cohort analysis ,female ,priority journal ,risk factor ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,abdominal abscess ,anastomosis leakage ,prospective study ,medicine.medical_specialty ,side to side anastomosis ,surgical infection ,reoperation ,Anastomosis ,Article ,NO ,03 medical and health sciences ,intestine resection ,length of stay ,male ,medicine ,intraoperative period ,follow up ,ileocecal resection ,controlled study ,human ,Adverse effect ,outcome assessment ,preoperative period ,ta3126 ,business.industry ,Postoperative complication ,Odds ratio ,medicine.disease ,surgical margin ,major clinical study ,Confidence interval ,hemicolectomy ,Parenteral nutrition ,protein blood level ,business ,abscess drainage - Abstract
Aim: Patient- and disease-related factors, as well as operation technique, all have the potential to impact on postoperative outcome in Crohn's disease. The available evidence is based on small series and often displays conflicting results. The aim was to investigate the effect of preoperative and intra-operative risk factors on 30-day postoperative outcome in patients undergoing surgery for Crohn's disease. Method: This was an international prospective snapshot audit including consecutive patients undergoing right hemicolectomy or ileocaecal resection. The study analysed a subset of patients who underwent surgery for Crohn's disease. The primary outcome measure was the overall Clavien–Dindo postoperative complication rate. The key secondary outcomes were anastomotic leak, reoperation, surgical site infection and length of stay in hospital. Multivariable binary logistic regression analyses were used to produce odds ratios and 95% confidence intervals. Results: In all, 375 resections in 375 patients were included. The median age was 37 and 57.1% were women. In multivariate analyses, postoperative complications were associated with preoperative parenteral nutrition (OR 2.36, 95% CI 1.10–4.97), urgent/expedited surgical intervention (OR 2.00, 95% CI 1.13–3.55) and unplanned intra-operative adverse events (OR 2.30, 95% CI 1.20–4.45). The postoperative length of stay in hospital was prolonged in patients who received preoperative parenteral nutrition (OR 31, 95% CI 1.08–1.61) and those who had urgent/expedited operations (OR 1.21, 95% CI 1.07–1.37). Conclusion: Preoperative parenteral nutritional support, urgent/expedited operation and unplanned intra-operative adverse events were associated with unfavourable postoperative outcome. Enhanced preoperative optimization and improved planning of operation pathways and timings may improve outcomes for patients. Colorectal Disease © 2017 The Association of Coloproctology of Great Britain and Ireland
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- 2018
26. Discriminating complicated from uncomplicated appendicitis by ultrasound imaging, computed tomography or magnetic resonance imaging: systematic review and meta-analysis of diagnostic accuracy.
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Bom, W. J., Bolmers, M. D., Gans, S. L., van Rossem, C. C., van Geloven, A. A. W., Bossuyt, P. M. M., Stoker, J., and Boermeester, M. A.
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ULTRASONIC imaging ,MAGNETIC resonance imaging ,SURGICAL emergencies - Abstract
Background: Discriminating complicated from uncomplicated appendicitis is crucial. Patients with suspected complicated appendicitis are best treated by emergency surgery, whereas those with uncomplicated appendicitis may be treated with antibiotics alone. This study aimed to obtain summary estimates of the accuracy of ultrasound imaging, CT and MRI in discriminating complicated from uncomplicated appendicitis Methods: A systematic literature review was conducted by an electronic search in PubMed, Embase and the Cochrane Library for studies describing the diagnostic accuracy of complicated versus uncomplicated appendicitis. Studies were included if the population comprised adults, and surgery or pathology was used as a reference standard. Risk of bias and applicability were assessed with QUADAS-2. Bivariable logitnormal random-effect models were used to estimate mean sensitivity and specificity. Results: Two studies reporting on ultrasound imaging, 11 studies on CT, one on MRI, and one on ultrasonography with conditional CT were included. Summary estimates for sensitivity and specificity in detecting complicated appendicitis could be calculated only for CT, because of lack of data for the other imaging modalities. For CT, mean sensitivity was 78 (95 per cent c.i. 64 to 88) per cent, and mean specificity was 91 (85 to 99) per cent. At a median prevalence of 25 per cent, the positive predictive value of CT for complicated appendicitis would be 74 per cent and its negative predictive value 93 per cent. Conclusion: Ultrasound imaging, CT and MRI have limitations in discriminating between complicated and uncomplicated appendicitis. Although CT has far from perfect sensitivity, its negative predictive value for complicated appendicitis is high. [ABSTRACT FROM AUTHOR]
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- 2021
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27. Combining intensive practice nurse counselling or brief general practitioner advice with varenicline for smoking cessation in primary care: Study protocol of a pragmatic randomized controlled trial
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van Rossem, C., van Rossem, C., Spigt, M., Smit, E.S., Viechtbauer, W., Mijnheer, K.K., van Schayck, C.P., Kotz, D., van Rossem, C., van Rossem, C., Spigt, M., Smit, E.S., Viechtbauer, W., Mijnheer, K.K., van Schayck, C.P., and Kotz, D.
- Abstract
Introduction: Combining behavioural support and pharmacotherapy is most effective for smoking cessation and recommended in clinical guidelines. Despite that smoking cessation assistance from the general practitioner can be effective, dissemination of clinical practice guidelines and efforts on upskilling has not lead to the routine provision of smoking cessation advice among general practitioners. Intensive counselling from the practice nurse could contribute to better smoking cessation rates in primary care. However, the effectiveness of intensive counselling from a practice nurse versus usual care from a general practitioner in combination with varenicline is still unknown. Materials and methods: A pragmatic randomized controlled trial was conducted comparing: (a) intensive individual counselling delivered by a practice nurse and (b) brief advice delivered by a general practitioner; both groups received 12-weeks of open-label varenicline. A minimum of 272 adult daily smoking participants were recruited and treated in their routine primary care setting. The primary outcome was defined as prolonged abstinence from weeks 9 to 26, biochemically validated by exhaled carbon monoxide. Data was analysed blinded according to the intention-to-treat principle and participants with missing data on their smoking status at follow-up were counted as smokers. Secondary outcomes included: one-year prolonged abstinence, short-term incremental cost-effectiveness, medication adherence, and baseline predictors of successful smoking cessation. Discussion: This trial is the first to provide scientific evidence on the effectiveness, cost-effectiveness, and potential mechanisms of action of intensive practice nurse counselling combined with varenicline under real-life conditions. This paper explains the methodology of the trial and discusses the pragmatic and/or explanatory design aspects.
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- 2015
28. right hemicolectomy and ileo-caecal resection: an international snapshot
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Pinkney, T, Battersby, N, Bhangu, A, Chaudhri, S, El-Hussuna, A, Frasson, M, Nepogodiev, D, Singh, B, Vennix, S, Zmora, O, Altomare, D, Bemelman, W, Christensen, P, D'Hoore, A, Laurberg, S, Morton, D, Rubbini, M, Vaizey, C, Magill, L, Perry, R, Sheward, N, Ives, N, Mehta, S, Cillo, M, Estefania, D, Uriburu, JP, Ruiz, H, Salomon, M, Makhmudov, A, Selnyahina, L, Varabei, A, Vizhynis, Y, Claeys, D, Defoort, B, Muysoms, F, Pletinckx, P, Vergucht, V, Debergh, I, Feryn, T, Reusens, H, Nachtergaele, M, Francart, D, Jehaes, C, Markiewicz, S, Monami, B, Weerts, J, Bouckaert, W, Houben, B, Knol, J, Sergeant, G, Vangertruyden, G, Haeck, L, Lange, C, Sommeling, C, Vindevoghel, K, Castro, S, De Bruyn, H, Huyghe, M, De Wolf, E, Reynders, D, van Overstraeten, AD, Wolthuis, A, Delibegovic, S, Christiani, A, Marchiori, M, de Moraes, CR, Tercioti, V, Arabadjieva, E, Bulanov, D, Dardanov, D, Stoyanov, V, Yonkov, A, Angelov, K, Maslyankov, S, Sokolov, M, Todorov, G, Toshev, S, Georgiev, Y, Karashmalakov, A, Zafirov, G, Wang, X, Condic, D, Kraljik, D, Mrkovic, H, Pavkovic, V, Raguz, K, Bencurik, V, Holaskova, E, Skrovina, M, Farkasova, M, Grolich, T, Kala, Z, Antos, F, Pruchova, V, Sotona, O, Chobola, M, Dusek, T, Ferko, A, Orhalmi, J, Hoch, J, Kocian, P, Martinek, L, Bernstein, I, Sunesen, KG, Leunbach, J, Thorlacius-Ussing, O, Oveson, AU, Chirstensen, SD, Gamez, V, Oeting, M, Loeve, US, Ugianskis, A, Jessen, M, Krarup, P, Linde, K, Mirza, Q, Stovring, JO, Erritzoe, L, Jakobsen, HL, Lykke, J, Colov, EP, Madsen, AH, Friis, TL, Funder, JA, Dich, R, Kjaer, S, Rasmussen, S, Schlesinger, N, Kjaer, MD, Qvist, N, Khalid, A, Ali, G, Hadi, S, Walker, LR, Kivela, A, Lehtonen, T, Lepisto, A, Scheinin, T, Siironen, P, Kossi, J, Kuusanmaki, P, Tomminen, T, Turunen, A, Rautio, T, Vierimaa, M, Huhtinen, H, Karvonen, J, Lavonius, M, Rantala, A, Varpe, P, Cotte, E, Francois, Y, Glehen, O, Kepenekian, V, Passot, G, Maggiori, L, Manceau, G, Panis, Y, Gout, M, Rullier, E, van Geluwe, B, Chafai, N, Lefevre, JH, Parc, Y, Tiret, E, Couette, C, Duchalais, E, Agha, A, Hornberger, M, Hungbauer, A, Iesalnieks, I, Weindl, I, Crescenti, F, Keller, M, Kolodziejski, N, Scherer, R, Sterzing, D, Bock, B, Boehm, G, El-Magd, M, Krones, C, Niewiera, M, Buhr, J, Cordesmeyer, S, Hoffmann, M, Kruckemeier, K, Vogel, T, Schon, M, Baral, J, Lukoschek, T, Munch, S, Pullig, F, Horisberger, K, Kienle, P, Magdeburg, J, Post, S, Batzalexis, K, Germanos, S, Agalianos, C, Dervenis, C, Gouvas, N, Kanavidis, P, Kottikias, A, Katsoulis, IE, Korkolis, D, Plataniotis, G, Sakorafas, G, Akrida, I, Argentou, M, Kollatos, C, Lampropoulos, C, Tsochatzis, S, Besznyak, I, Bursics, A, Egyed, T, Papp, G, Svastics, I, Atladottir, J, Moller, P, Sigurdsson, H, Stefansson, T, Valsdottir, E, Andrews, E, Foley, N, Hechtl, D, Majeed, M, McCourt, M, Hanly, A, Hyland, J, Martin, S, O'Connell, PR, Winter, D, Connelly, T, Joyce, W, Wrafter, P, Berkovitz, R, Avital, S, Yahia, IH, Hermann, N, Shpitz, B, White, I, Lishtzinsky, Y, Tsherniak, A, Wasserberg, N, Horesh, N, Keler, U, Pery, R, Shapiro, R, Tulchinsky, H, Badran, B, Dayan, K, Iskhakov, A, Lecaros, J, Nabih, N, Angrima, I, Bardini, R, Pizzolato, E, Tonello, M, Arces, F, Balestri, R, Ceccarelli, C, Prosperi, V, Rossi, E, Giannini, I, Vincenti, L, Altomare, DF, Di Candido, F, Di Iena, M, Guglielmi, A, Caputi-Iam-Brenghi, O, Marsanic, P, Mellano, A, Muratore, A, Annecchiarico, M, Bencini, L, Bona-Pasta, SA, Coratti, A, Guerra, F, Asteria, CR, Boccia, L, Gerard, L, Pascariello, A, Manca, G, Marino, F, Casaril, A, Inama, M, Moretto, G, Bacchelli, C, Carvello, M, Mariani, N, Montorsi, M, Spinelli, A, Romairone, E, Scabini, S, Belli, A, Bianco, F, De Franciscis, S, Romano, GM, Delrio, P, Pace, U, Rega, D, Sassaroli, C, Scala, D, De Luca, R, Ruggieri, E, Elbetti, C, Garzi, A, Romoli, L, Scatizzi, M, Vannucchi, A, Curletti, G, Durante, V, Galleano, R, Mariani, F, Reggiani, L, Bellomo, R, Infantino, A, Franceschilli, L, Sileri, P, Clementi, I, Coletta, D, La Torre, F, Mingoli, A, Velluti, F, Di Giacomo, A, Fiorot, A, Massani, M, Padoan, L, Ruffolo, C, Caruso, S, Franceschini, F, Laessig, R, Monaci, I, Rontini, M, De Nardi, P, Elmore, U, Lemma, M, Rosati, R, Tamburini, A, De Luca, M, Sartori, A, Benevento, A, Bottini, C, Ferrari, CC, Pata, F, Tessera, G, Pellino, G, Selvaggi, F, Lanzani, A, Romano, F, Sgroi, G, Steccanella, F, Turati, L, Yamamoto, T, Ancans, G, Gerkis, S, Leja, M, Pcolkins, A, Sivins, A, Latkauskas, T, Lizdenis, P, Saladzin-Skas, Z, Svagzdys, S, Tamelis, A, Razbadauskas, A, Sokolovas, M, Dulskas, A, Samalavicius, N, Jotautas, V, Mikalauskas, S, Poskus, E, Poskus, T, Strupas, K, Camenzuli, C, Cini, C, Predrag, A, Psaila, J, Spiteri, N, Buskens, C, de Groof, EJ, Gooszen, J, Tanis, P, Belgers, E, Davids, P, Furnee, E, Postma, E, Pronk, A, Smakman, N, Clermonts, S, Zimmerman, D, Omloo, J, van der Zaag, E, van Duijvendijk, P, Wassenaar, E, Bruijninckx, M, de Graff, E, Doornebosch, P, Tetteroo, G, Vermaas, M, Iordens, G, Knops, 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- Subjects
international ,Anastomotic leak ,colorectal cancer ,Crohn's disease ,epidemiology - Abstract
Aim The anastomosis technique used following right-sided colonic resection is widely variable and may affect patient outcome. This study aimed to assess the association between leak and anastomosis technique (stapled vs handsewn). Method This was a prospective, multicentre, international audit including patients undergoing elective or emergency right hemicolectomy or ileo-caecal resection operations over a 2-month period in early 2015. The primary outcome measure was the presence of anastomotic leak within 30 days of surgery, determined using a prespecified definition. Mixed effects logistic regression models were used to assess the association between leak and anastomosis method, adjusting for patient, disease and operative cofactors, with centre included as a random-effect variable. Results This study included 3208 patients, of whom 78.4% (n = 2515) underwent surgery for malignancy and 11.7% (n = 375) underwent surgery for Crohn's disease. An anastomosis was performed in 94.8% (n = 3041) of patients, which was handsewn in 38.9% (n = 1183) and stapled in 61.1% (n = 1858). Patients undergoing hand-sewn anastomosis were more likely to be emergency admissions (20.5% handsewn vs 12.9% stapled) and to undergo open surgery (54.7% handsewn vs 36.6% stapled). The overall anastomotic leak rate was 8.1% (245/3041), which was similar following handsewn (7.4%) and stapled (8.5%) techniques (P = 0.3). After adjustment for cofactors, the odds of a leak were higher for stapled anastomosis (adjusted OR = 1.43; 95% CI: 1.04-1.95; P = 0.03). Conclusion Despite being used in lower-risk patients, stapled anastomosis was associated with an increased anastomotic leak rate in this observational study. Further research is needed to define patient groups in whom a stapled anastomosis is safe.
- Published
- 2017
29. Relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection : an international snapshot audit
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M., Cuk, V. V., Kenic, M., Kovacevic, B., Krdzic, I., Korcek, J., Rems, M., Toplak, J., Escarrã¢, J., Gil Barrionuevo, M., Golda, T., Kreisler Moreno, E., Zerpa Martin, C., à lvarez Laso, C., Cumplido, P., Padin, H., Baixauli Fons, J., Hernández-Lizoain, J., Martinez-Ortega, P., Molina-Fernández, M., Sánchez-Justicia, C., Antonio Gracia Solanas, J., de Laspra, E. Córdoba DÃaz, Echazarreta-Gallego, E., Elia-Guedea, M., Ramirez, J., Arredondo Chaves, J., Diez González, P., Elosua, T., Sahagãºn, J., Turienzo Frade, A., à lvarez Conde, J., Castrillo, E., Diaz Maag, R., Maderuelo, V., Saldarriaga, L., Aldrey Cao, I., Fernández Varela, X., Núñez Fernández, S., Parajó Calvo, A., Villar à lvarez, S., Blesa Sierra, I., Lozano, R., Mã¡rquez, M., Porcel, O., Menendez, P., Fernández Hevia, M., Flores Sigüenza, L., Jimenez Toscano, M., Lacy Fortuny, A., Ordoñez Trujillo, J., Espi, A., Garcia-Botello, S., MartÃn-Arévalo, J., Moro-Valdezate, D., Pla-MartÃ, V., Blanco-Antona, F., Abrisqueta, J., Ibañez Canovas, N., Lujan Mompean, J., Escolá Ripoll, D., Martinez Gonzalez, S., Parodi, J., Fernández López, A., Ramos Fernández, M., Castellvi Valls, J., de Zarate, L. Ortiz, Ribas, R., Sabia, D., Viso, L., Alonso Gonçalves, S., José Gil Egea, M., Pascual Damieta, M., Pera, M., Salvans Ruiz, S., Bernal, J., Landete, F., Ais, G., Etreros, J., Aguiló Lucia, J., Boscã¡, A., Deusa, S., GarcÃa del Caño, J., Viciano, V., GarcÃa-Armengol, J., Roig, J., Blas, J., Escartin, J., Fatã¡s, J., Fernando, J., Ferrer, R., Arias Pacheco, R., GarcÃa Flórez, L., Moreno Gijón, M., Otero DÃez, J., Solar Garcia, L., Aguilar Teixido, F., Balaguer Ojo, C., Bargallo Berzosa, J., Lamas Moure, S., Enrique Sierra, J., Fermiã±ã¡n, A., Herrerias, F., Rufas, M., Viã±as, J., Codina-Cazador, A., Farrã©s, R., Gã³mez, N., Juliã , D., Planellas, P., Lã³pez, J., Luna, A., Maristany, C., Muñoz Duyos, A., Puã©rtolas, N., Alcantara Moral, M., Serra-Aracil, X., Concheiro Coello, P., Gã³mez, D., Carton, C., Miguel, A., Reoyo Pascual, F., Valero Cerrato, X., Zambrano Muñoz, R., Cervera-Aldama, J., GarcÃa González, J., Ramos-Prada, J., SantamarÃa-Olabarrieta, M., Urigüen-EcheverrÃa, A., Coves Alcover, R., Espinosa Soria, J., Fernandez Rodriguez, E., Hernandis Villalba, J., Maturana Ibañez, V., De la Torre Gonzalez, F., Huerga, D., Pérez Viejo, E., Rivera, A., Ruiz Ucar, E., Garcia-Septiem, J., Jimã©nez, V., Jiménez Miramón, J., Ramons Rodriquez, J., Rodriguez Alvarez, V., Garcea, A., Ponchietti, L., Borda, N., Enriquez-Navascues, J., Saralegui, Y., Febles Molina, G., Nogues, E., RodrÃguez Méndez, Ã. ., Roque Castellano, C., Sosa Quesada, Y., Alvarez-Gallego, M., Pascual, I., Rubio-Perez, I., Diaz-San Andrés, B., Tone-Villanueva, F., Alonso, J., Cagigas, C., Castillo, J., Gã³mez, M., MartÃn-Parra, J., Mengual Ballester, M., Pellicer Franco, E., Soria Aledo, V., Valero Navarro, G., Caballero RodrÃguez, E., De Chaves, P. Gonzalez, Hernandez, G., Perez Alvarez, A., Soto Sanchez, A., Cesar Becerra Garcia, F., Guillermo Alonso Roque, J., López RodrÃguez Arias, F., Del Valle Ruiz, S. R., De La Villa, G. Sánchez, Compaã±, A., GarcÃa MarÃn, A., Nofuentes, C., Orts Micó, F., Pérez Auladell, V., Carrasco, M., Duque Perez, C., Gálvez-Pastor, S., Navarro Garcia, I., Sanchez Perez, A., Enjuto, D., Manuel Bujalance, F., Marcelin, N., Pã©rez, M., Serrano GarcÃa, R., Cabrera, A., de la Portilla, F., Diaz-Pavon, J., Jimenez-Rodriguez, R., Vazquez-Monchul, J., Daza González, J., Gómez Pérez, R., Rivera Castellano, J., de la Rua, J. Roldán, Errasti Alustiza, J., Fernandez, L., Romeo Ramirez, J., Sardon Ramos, J., Cermeño Toral, B., Alias, D., Garcia-Olmo, D., Guadalajara, H., Herreros, M., Pacheco, P., Lima, P., MartÃnez Alegre, J., Ortega, I., Picardo Nieto Antonio, A., Caro, A., Escuder, J., Feliu, F., Millan, M., Frangi Caregnato, A., Lozoya Trujillo, R., RodrÃguez Carrillo, R., Ruiz Carmona, M., Alonso, N., Ambrona Zafra, D., Amilka Ayala Candia, B. J., Pineño Flores, C., Alcazar Montero, J., Angoso Clavijo, M., Garcia, J., Sanchez Tocino, J., Gómez-Alcazar, C., Costa-Navarro, D., Ferri-Romero, J., Rey-Riveiro, M., Romero-Simó, M., Arencibia, B., Esclapez, P., GarcÃa-Granero, E., Granero, P., Medina Fernández, F. J., Gallardo Herrera, A. B., Diaz López, C., Navarro Rodriguez, E., Torres Tordera, E., Arenal, J., Citores, M., Marcos, J., Sã¡nchez, J., Tinoco, C., Espin, E., Garcia Granero, A., Jimenez Gomez, L., Sanchez Garcia, J., Vallribera, F., Folkesson, J., Skã¶ldberg, F., Bergman, K., Borgstrã¶m, E., Frey, J., Silfverberg, A., Sã¶derholm, M., Nygren, J., Segelman, J., Gustafsson, D., Lagerqvist, A., Papp, A., Pelczar, M., Abraham-Nordling, M., Ahlberg, M., Sjovall, A., Tengstrom, J., Hagman, K., Chabok, A., Ezra, E., Nikberg, M., Smedh, K., Tiselius, C., Al-Naimi, N., Dao Duc, M., Meyer, J., Mormont, M., Ris, F., Prevost, G., Villiger, P., Hoffmann, H., Kettelhack, C., Kirchhoff, P., Oertli, D., Weixler, B., Aytac, B., Leventoglu, S., Mentes, B., Yuksel, O., Demirbas, S., Busra Ozkan, B., Selçuk Özbalci, G., Sungurtekin, U., Gã¼lcã¼, B., Ozturk, E., Yilmazlar, T., Challand, C., Fearnhead, N., Hubbard, R., Kumar, S., Arthur, J., Barben, C., Skaife, P., Slawik, S., Williams, M., Zammit, M., Barker, J., Sarantitis, I., Slawinski, C., Clifford, R., Eardley, N., Johnson, M., Mcfaul, C., Vimalachandran, D., Allan, S., Bell, A., Oates, E., Shanmugam, V., Brigic, A., Halls, M., Pucher, P., Stubbs, B., Agarwal, T., Chopada, A., Mallappa, S., Pathmarajah, M., Sugden, C., Brown, C., Macdonald, E., Mckay, A., Richards, J., Robertson, A., Kaushal, M., Patel, P., Tezas, S., Touqan, N., Ayaani, S., Marimuthu, K., Piramanayagam, B., Vourvachis, M., Iqbal, N., Korsgen, S., Seretis, C., Shariff, U., Arnold, S., Chan, H., Clark, E., Fernandes, R., Moran, B., Bajwa, A., Mcarthur, D., Cao, K., Cunha, P., Pardoe, H., Quddus, A., Theodoropoulou, K., Bolln, C., Denys, G., Gillespie, M., Manimaran, N., Reidy, J., Malik, A. I., Malik, A., Pitt, J., Aryal, K., El-Hadi, A., Lal, R., Pal, A., Velchuru, V., Oliveira Cunha, M., Thomas, M., Bains, S., Boyle, K., Miller, A., Norwood, M., Yeung, J., Goian, L., Gurjar, S., Saghir, W., Sengupta, N., Stewart-Parker, E., Bailey, S., Khalil, T., Lawes, D., Nikolaou, S., Omar, G., Church, R., Muthiah, B., Garrett, W., Marsh, P., Obeid, N., Chandler, S., Coyne, P., Evans, M., Hunt, L., Lim, J., Oliphant, Z., Papworth, E., Weaver, H., Cuiñas Leon, K., Williams, G., Hernon, J., Kapur, S., Moosvi, R., Shaikh, I., Swafe, L., Aslam, M., Evans, J., Ihedioha, U., Kang, P., Merchant, J., Hompes, R., Middleton, R., Broomfield, A., Crutten-Wood, D., Foster, J., Nash, G., Akhtar, M., Boshnaq, M., Eldesouky, S., Mangam, S., Rabie, M., Ahmed, J., Khan, J., Ming Goh, N., Shamali, A., Stefan, S., Thompson, C., Amin, A., Docherty, J., Lim, M., Walker, K., Watson, A., Hossack, M., Mackenzie, N., Paraoan, M., Alam, N., Daniels, I., Narang, S., Pathak, S., Smart, N., Al-Qaddo, A., Codd, R., Rutka, O., Bronder, C., Crighton, I., Davies, E., Raymond, T., Bookless, L., Griffiths, B., Plusa, S., Carlson, G., Harrison, R., Lees, N., Mason, C., Quayle, J., Branagan, G., Broadhurst, J., Chave, H., Sleight, S., Awad, F., Cruickshank, N., Joy, H., Boereboom, C., Daliya, P., Dhillon, A., Watson, N., Watson, R., Artioukh, D., Gokul, K., Javed, M., Kong, R., Sutton, J., Faiz, O., Jenkins, I., Leo, C. A., Samaranayake, S. F., Warusavitarne, J., Arya, S., Bhan, C., Mukhtar, H., Oshowo, A., Wilson, J., Duff, S., Fatayer, T., Mbuvi, J., Sharma, A., Cornish, J., Davies, L., Harries, R., Morris, C., Torkington, J., Knight, J., Lai, C., Shihab, O., Tzivanakis, A., Hussain, A., Luke, D., Padwick, R., Torrance, A., Tsiamis, A., Dawson, P., Balfour, A., Brady, R., Mander, J., Paterson, H., Chandratreya, N., Chu, H., Cutting, J., Vernon, S., Wai Ho, C., Andreani, S., Patel, H., Yan Qi Tan, J., Iqbal, A., Khan, A., Perrin, K., Raza, A., Tan, S., Other departments, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA - Cancer Treatment and Quality of Life, Surgery, Meyer, Jérémy, Al-Naimi, Noof, Mormont, Murielle, Ris, Frédéric, 2015 European Society of Coloproctology collaborating, Group, Rosati, R, Sileri, P, and Radiology and nuclear medicine
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medicine.medical_specialty ,Leak ,SURGERY ,colorectal cancer ,Audit ,030230 surgery ,Anastomosis ,Logistic regression ,NO ,Resection ,03 medical and health sciences ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Primary outcome ,All institutes and research themes of the Radboud University Medical Center ,Anastomotic leak, colorectal cancer, Crohn's disease, epidemiology, international ,Journal Article ,Medicine ,Anastomotic leak ,LEAK ,COMPLICATIONS ,ddc:617 ,business.industry ,MORTALITY ,Gastroenterology ,Crohns disease ,anastomotic leak ,crohn's disease ,epidemiology ,international ,ta3121 ,3. Good health ,Surgery ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,Crohn's disease ,DEFINITION ,030220 oncology & carcinogenesis ,Mixed effects ,RISK-FACTORS ,business ,Right hemicolectomy - Abstract
Aim The anastomosis technique used following right-sided colonic resection is widely variable and may affect patient outcome. This study aimed to assess the association between leak and anastomosis technique (stapled vs handsewn)., Method This was a prospective, multicentre, international audit including patients undergoing elective or emergency right hemicolectomy or ileo-caecal resection operations over a 2-month period in early 2015. The primary outcome measure was the presence of anastomotic leak within 30 days of surgery, determined using a prespecified definition. Mixed effects logistic regression models were used to assess the association between leak and anastomosis method, adjusting for patient, disease and operative cofactors, with centre included as a random-effect variable., Results This study included 3208 patients, of whom 78.4% (n = 2515) underwent surgery for malignancy and 11.7% (n = 375) underwent surgery for Crohn's disease. An anastomosis was performed in 94.8% (n = 3041) of patients, which was handsewn in 38.9% (n = 1183) and stapled in 61.1% (n = 1858). Patients undergoing hand-sewn anastomosis were more likely to be emergency admissions (20.5% handsewn vs 12.9% stapled) and to undergo open surgery (54.7% handsewn vs 36.6% stapled). The overall anastomotic leak rate was 8.1% (245/3041), which was similar following handsewn (7.4%) and stapled (8.5%) techniques (P = 0.3). After adjustment for cofactors, the odds of a leak were higher for stapled anastomosis (adjusted OR = 1.43; 95% CI: 1.04-1.95; P = 0.03)., Conclusion Despite being used in lower-risk patients, stapled anastomosis was associated with an increased anastomotic leak rate in this observational study. Further research is needed to define patient groups in whom a stapled anastomosis is safe.
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- 2017
30. Interobserver variability in the classification of appendicitis during laparoscopy
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van den Boom, A L, primary, de Wijkerslooth, E M L, additional, Mauff, K A L, additional, Dawson, I, additional, van Rossem, C C, additional, Toorenvliet, B R, additional, and Wijnhoven, B P L, additional
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- 2018
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31. Benchmarking recent national practice in rectal cancer treatment with landmark randomized controlled trials
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Borstlap, W. A. A., Borstlap, W. A. A., Deijen, C. L., den Dulk, M., Bonjer, H. J., van de Velde, C. J., Bemelman, W. A., Tanis, P. J., Aalbers, A., Acherman, Y., Algie, G. D., von Geu-sau, B. Alting, Amelung, F., Aukema, T. S., Bakker, I. S., Bartels, S. A., Basha, S., Bastiaansen, A. J. N. M., Belgers, E., Bleeker, W., Blok, J., Bosker, R. J. I., Bosmans, J. W., Boute, M. C., Bouvy, N. D., Bouwman, H., Brandt-Kerkhof, A., Brinkman, D. J., Bruin, S., Bruns, E. R. J., Burbach, J. P. M., Burger, J. W. A., Buskens, C. J., Clermonts, S., Coene, P. P. L. O., Compaan, C., Consten, E. C. J., Darbyshire, T., de Mik, S. M. L., de Groot, I., Heemskerk, J., Heijnen, B., Hoogland, P., Jongen, A. C., Kool, M. E., van Rossem, C. C., Rutten, H. J., Schouten, N., Simkens, G. A., Wetzel, M., Wouters, M. W., Dutch Snapshot Res Grp, Borstlap, W. A. A., Borstlap, W. A. A., Deijen, C. L., den Dulk, M., Bonjer, H. J., van de Velde, C. J., Bemelman, W. A., Tanis, P. J., Aalbers, A., Acherman, Y., Algie, G. D., von Geu-sau, B. Alting, Amelung, F., Aukema, T. S., Bakker, I. S., Bartels, S. A., Basha, S., Bastiaansen, A. J. N. M., Belgers, E., Bleeker, W., Blok, J., Bosker, R. J. I., Bosmans, J. W., Boute, M. C., Bouvy, N. D., Bouwman, H., Brandt-Kerkhof, A., Brinkman, D. J., Bruin, S., Bruns, E. R. J., Burbach, J. P. M., Burger, J. W. A., Buskens, C. J., Clermonts, S., Coene, P. P. L. O., Compaan, C., Consten, E. C. J., Darbyshire, T., de Mik, S. M. L., de Groot, I., Heemskerk, J., Heijnen, B., Hoogland, P., Jongen, A. C., Kool, M. E., van Rossem, C. C., Rutten, H. J., Schouten, N., Simkens, G. A., Wetzel, M., Wouters, M. W., and Dutch Snapshot Res Grp
- Abstract
Aim A Snapshot study design eliminates changes in treatment and outcome over time. This population based Snapshot study aimed to determine current practice and outcome of rectal cancer treatment with published landmark randomized controlled trials as a benchmark.Method In this collaborative research project, the dataset of the Dutch Surgical Colorectal Audit was extended with additional treatment and long-term outcome data. All registered patients who underwent resection for rectal cancer in 2011 were eligible. Baseline characteristics and outcome were evaluated against the results of the Dutch TME trial and the COLOR II trial from which the original datasets were obtained.Results A total of 71 hospitals participated, and data were completed for 2102 out of the potential 2633 patients (79.8%). Median follow-up was 41 (interquartile range 25-47) months. Overall circumferential resection margin (CRM) involvement was 9.3% in the Snapshot cohort and 18.5% in the Dutch TME trial. CRM positivity after laparoscopic resection was 7.8% in the Snapshot and 9.5% in the COLOR II trial. Three-year overall local recurrence rate in the Snapshot was 5.9%, with a disease-free survival of 67.1% and overall survival of 79.5%. Benchmarking with the randomized controlled trials revealed an overall favourable long-term outcome of the Snapshot cohort.Conclusion This study showed that current rectal cancer care in a large unselected Dutch population is of high quality, with less positive CRM since the TME trial and oncologically safe implementation of minimally invasive surgery after the COLOR II trial.
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- 2017
32. Wirksamkeit intensiver verhaltenstherapeutischer Unterstützung durch MFA versus hausärztlicher Kurzberatung in Kombination mit Vareniclin bei der Tabakentwöhnung: eine pragmatische, randomisierte Studie in Hausarztpraxen
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van Rossem, C, Spigt, M, Viechtbauer, W, Lucas, AE, van Schayck, OC, and Kotz, D
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Tabakabhängigkeit ,ddc: 610 ,Tabakentwöhnung ,Hausärztliche Kurzberatung Tabakentwöhnung ,schädlicher Gebrauch von Tabak ,610 Medical sciences ,Medicine ,Vareniclin ,Rauchen - Abstract
Hintergrund: Zur Rauchentwöhnung empfehlen klinische Richtlinien die Kombination aus verhaltenstherapeutischer Unterstützung und Pharmakotherapie. Intensivere Unterstützung führt laut einiger Studien zu höheren Abstinenzraten, so dass intensivierte verhaltenstherapeutische Maßnahmen[zum vollständigen Text gelangen Sie über die oben angegebene URL], 50. Kongress für Allgemeinmedizin und Familienmedizin
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- 2016
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33. Diagnosing acute appendicitis: surgery or imaging?
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van Rossem, C. C., primary, Bolmers, M. D. M., additional, Schreinemacher, M. H. F., additional, Bemelman, W. A., additional, van Geloven, A. A. W., additional, Pinkney, T. D., additional, and Bhangu, A., additional
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- 2016
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34. Prospective nationwide outcome audit of surgery for suspected acute appendicitis
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van Rossem, C C, primary, Bolmers, M D M, additional, Schreinemacher, M H F, additional, van Geloven, A A W, additional, Bemelman, W A, additional, Acker, G J D, additional, Akkermans, B, additional, Akkersdijk, G J M, additional, Algie, G D, additional, Allema, J H, additional, Andeweg, C S, additional, Appeldorn, N, additional, Baal, J G, additional, Bakker, C M, additional, Bartels, S A L, additional, Berg, C, additional, Boekestijn, B, additional, Boer, F C, additional, Boerma, D, additional, Boom, A L, additional, Boute, M C, additional, Bouwense, S A W, additional, Bransen, J, additional, Brussel, F A, additional, Busch, O R C, additional, Castro, S M M, additional, Cense, H A, additional, Croese, C, additional, Dalen, T, additional, Dawson, I, additional, Dessel, E, additional, Dettmers, R, additional, Dhar, N, additional, Dohmen, F Y M, additional, Dongen, K W, additional, Duijvendijk, P, additional, Dulfer, R R, additional, Dwars, B J, additional, Eerenberg, J P, additional, Elst, M, additional, Ende, E, additional, Fassaert, L M M, additional, Fikkers, J T, additional, Foppen, J W, additional, Furnee, E J B, additional, Garssen, F P, additional, Gerhards, M F, additional, Goor, H, additional, Gorter, R R, additional, Graaf, J S, additional, Graat, L J, additional, Groote, J, additional, Ham, A C, additional, Hamming, J F, additional, Hamminga, J T H, additional, Harst, E, additional, Heemskerk, J, additional, Heij, H A, additional, Heijne, A, additional, Heikens, J T, additional, Heineman, E, additional, Hertogs, R, additional, Heurn, E, additional, Hil, L C L, additional, Hoofwijk, A G M, additional, Hulsker, C C C, additional, Hunen, D R M, additional, Ibelings, M S, additional, Klaase, J M, additional, Klicks, R, additional, Knaapen, L, additional, Kortekaas, R T J, additional, Kruyt, F, additional, Kwant, S, additional, Lases, S S, additional, Lettinga, T, additional, Loupatty, A, additional, Matthijsen, R A, additional, Minnee, R C, additional, Mirck, B, additional, Mitalas, L, additional, Moes, D, additional, Moorman, A M, additional, Nieuwenhuijs, V B, additional, Nieuwenhuijzen, G A P, additional, Nijk, P D, additional, Omloo, J M T, additional, Ottenhof, A G, additional, Palamba, H W, additional, Peet, D L, additional, Pereboom, I T A, additional, Plaisier, P W, additional, Ploeg, A P T, additional, Raber, M H, additional, Reijnen, M M P J, additional, Rijna, H, additional, Rosman, C, additional, Roumen, R M H, additional, Schmitz, R F, additional, Velden, A P Schouten, additional, Schreurs, W H, additional, Sigterman, T A, additional, Smeets, H J, additional, Sonneveld, D J A, additional, Sosef, M N, additional, Spoor, S F, additional, Stassen, L P S, additional, Steensel, L, additional, Stortelder, E, additional, Straatman, J, additional, Susante, H J, additional, Hoog, D E N M Suykerbuyk, additional, Scheltinga, C Terwisscha, additional, Toorenvliet, B R, additional, Verbeek, B M, additional, Verbeek, P C M, additional, Verseveld, M, additional, Volders, J H, additional, Vriens, M R, additional, Vriens, P W H E, additional, Vrouenraets, B C, additional, Wall, B J M, additional, Wegdam, J A, additional, Westerduin, E, additional, Wever, J J, additional, Wijffels, N A T, additional, Wijnhoven, B P L, additional, Winkel, T A, additional, Zee, D C, additional, Zeillemaker, A M, additional, and Zietse, C, additional
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- 2015
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35. Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial
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Vennix, Sandra, primary, Musters, Gijsbert D, additional, Mulder, Irene M, additional, Swank, Hilko A, additional, Consten, Esther C, additional, Belgers, Eric H, additional, van Geloven, Anna A, additional, Gerhards, Michael F, additional, Govaert, Marc J, additional, van Grevenstein, Wilhelmina M, additional, Hoofwijk, Anton G, additional, Kruyt, Philip M, additional, Nienhuijs, Simon W, additional, Boermeester, Marja A, additional, Vermeulen, Jefrey, additional, van Dieren, Susan, additional, Lange, Johan F, additional, Bemelman, Willem A, additional, Hop, W C, additional, Opmeer, B C, additional, Reitsma, J B, additional, Scholte, R A, additional, Waltmann, E W H, additional, Legemate, D A, additional, Bartelsman, J F, additional, Meijer, D W, additional, de Brouwer, M, additional, van Dalen, J, additional, Durbridge, M, additional, Geerdink, M, additional, Ilbrink, G J, additional, Mehmedovic, S, additional, Middelhoek, P, additional, Di Saverio, Salomone, additional, Boom, M J, additional, Consten, E C J, additional, van der Bilt, J D W, additional, van Olden, G D J, additional, Stam, M A W, additional, Verweij, M S, additional, Busch, O R C, additional, Buskens, C J, additional, El-Massoudi, Y, additional, Kluit, A B, additional, van Rossem, C C, additional, Schijven, M P, additional, Tanis, P J, additional, Unlu, C, additional, Gerhards, M F, additional, Karsten, T M, additional, de Nes, L C, additional, Rijna, H, additional, van Wagensveld, B A, additional, Koffeman, G I, additional, Steller, E P, additional, Tuynman, J B, additional, Bruin, S C, additional, van der Peet, D L, additional, Blanken-Peeters, C F J M, additional, Cense, H A, additional, Jutte, E, additional, Crolla, R M P H, additional, van der Schelling, G P, additional, van Zeeland, M, additional, de Graaf, E J R, additional, Groenendijk, R P R, additional, Vermaas, M, additional, Schouten, O, additional, de Vries, M R, additional, Prins, H A, additional, Lips, D J, additional, Bosker, R J I, additional, van der Hoeven, J A B, additional, Diks, J, additional, Plaisier, P W, additional, Kruyt, P M, additional, Sietses, C, additional, Stommel, M W J, additional, Nienhuijs, S W, additional, de Hingh, I H J T, additional, Luyer, M D P, additional, van Montfort, G, additional, Ponten, E H, additional, Smulders, J F, additional, van Duyn, E B, additional, Klaase, J M, additional, Swank, D J, additional, Ottow, R T, additional, Stockmann, H B A C, additional, Vermeulen, J, additional, Vuylsteke, R J C L M, additional, Belgers, H J, additional, Fransen, S, additional, von Meijenfeldt, E M, additional, Sosef, M N, additional, van Geloven, A A W, additional, Hendriks, E R, additional, ter Horst, B, additional, Leeuwenburgh, M M N, additional, van Ruler, O, additional, Vogten, J M, additional, Vriens, E J C, additional, Westerterp, M, additional, Eijsbouts, Q A J, additional, Bentohami, A, additional, Bijlsma, T S, additional, de Korte, N, additional, Nio, D, additional, Govaert, M J P M, additional, Joosten, J J A, additional, Tollenaar, R A E M, additional, Stassen, L P S, additional, Wiezer, M J, additional, Hazebroek, E J, additional, Smits, A B, additional, van Westreenen, H L, additional, Lange, J F, additional, Brandt, A, additional, Nijboer, W N, additional, Toorenvliet, B R, additional, Weidema, W F, additional, Coene, P P L O, additional, Mannaerts, G H H, additional, den Hartog, D, additional, de Vos, R J, additional, Zengerink, J F, additional, Hoofwijk, A G M, additional, Hulsewé, K W E, additional, Melenhorst, J, additional, Stoot, J H M B, additional, Steup, W H, additional, Huijstee, P J, additional, Merkus, J W S, additional, Wever, J J, additional, Maring, J K, additional, Heisterkamp, J, additional, van Grevenstein, W M U, additional, Vriens, M R, additional, Besselink, M G H, additional, Borel Rinkes, I H M, additional, Witkamp, A J, additional, Slooter, G D, additional, Konsten, J L M, additional, Engel, A F, additional, Pierik, E G J M, additional, Frakking, T G, additional, van Geldere, D, additional, Patijn, G A, additional, D'Hoore, A J L, additional, de Buck van Overstraeten, A, additional, Miserez, M, additional, Terrasson, I, additional, Wolthuis, A, additional, and De Blasiis, M G, additional
- Published
- 2015
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36. Combining intensive practice nurse counselling or brief general practitioner advice with varenicline for smoking cessation in primary care: Study protocol of a pragmatic randomized controlled trial
- Author
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van Rossem, C., primary, Spigt, M., additional, Smit, E.S., additional, Viechtbauer, W., additional, Mijnheer, K.K., additional, van Schayck, C.P., additional, and Kotz, D., additional
- Published
- 2015
- Full Text
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37. linguistic annotation of the Creole texts
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den Besten, J.B., van Rossem, C., van der Voort, H.G.A., van der Voort, H., and Faculteit der Letteren
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- 1996
38. Negerhollands: An Introduction
- Author
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den Besten, J.B., Muysken, P.C., van Rossem, C., van der Voort, H.G.A., van der voort, H.G.A., and Faculteit der Letteren
- Published
- 1996
39. Creole literature
- Author
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Adamson, L.G., van Rossem, C., Muysken, P.C., Arends, J., Smith, N.S.H., and Faculteit der Letteren
- Published
- 1994
40. Managing Pediatric Asthma Exacerbations: The Role of Timely Systemic Corticosteroid Administration in Emergency Care Settings-A Multicentric Retrospective Study.
- Author
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Antonino L, Goossens E, van Olmen J, Bael A, Hellinckx J, Van Ussel I, Wouters A, Jonckheer T, Martens T, Van Nuijs S, Van Rossem C, Driesen Y, Jouret N, Ter Haar E, Rozenberg S, Vanderschaeghe E, van Steijn S, Verhulst S, and Van Hoorenbeeck K
- Abstract
Background: Asthma is the most prevalent chronic respiratory condition in children. An asthma exacerbation (AE) is a frequent reason for emergency department (ED) visits. An important step in the management of a moderate to severe AE is the administration of systemic corticosteroids (SCS) within 1 h after ED presentation. This study aimed to determine the timing of SCS administration and correlate this with the length of stay and oxygen therapy duration and to explore factors predicting timely administration., Methods: This study used a retrospective multicenter observational design based on electronic medical records review. Children aged < 18 years, presenting to the ED with a moderate to severe AE were included., Results: 205 patients were included. Only 28 patients received SCS within 60 min after ED arrival. The median time to SCS administration was 169 min (Q
1 92-Q3 380). A correlation was found between timing and oxygen treatment duration (r = 0.363, p < 0.001) and length of stay (r = 0.368, p < 0.001). No patient characteristics predicted timely SCS administration., Conclusions: Three in four children who presented with a moderate to severe AE at the ED did not receive SCS within the first hour. A prolonged timing of SCS administration correlated with a prolonged length of stay and extended need for oxygen support.- Published
- 2024
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41. Pseudomonas aeruginosa in children with cerebral palsy: a prospective study.
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Romaen K, Van Ussel I, Van Rossem C, Kenis S, Ceulemans B, Van Hoorenbeeck K, and Verhulst S
- Abstract
Introduction: Children with cerebral palsy (CP) often present with chronic respiratory symptoms. Pseudomonas aeruginosa (PA), is a known pathogen associated with more severe respiratory disease. Preventive actions to eradicate this bacterium and to improve the respiratory condition of children with CP could be very valuable. Therefore, we assessed the prevalence of PA and its association with respiratory disease., Methods: Throat swabs were taken in children with CP, aged 0-18 years. Data from patient records were extracted from the electronic medical records. Follow-up of respiratory symptoms was done by the Liverpool respiratory symptom questionnaire (LRSQ) after 3 months., Results: A throat swab and a completed LRSQ after 3 months were received from 79 children with CP. Twenty-eight patients (35.4%) were found to have at least one positive respiratory culture. Only 4 patients (5.1%) were contaminated with PA. Gram negative bacteria were isolated in 21.5% of the positive throat swabs, S. aureus was found in 13.9%. Most pathogens were found in patients with higher GMFCS score (GMFCS IV and V). Results of the LRSQ showed that 52.1% of these patients reported having 1 cold in the past 3 months., Discussion: The prevalence of PA in our population of children with CP is low, gram-negative bacteria were most commonly found. The respiratory consequences of being colonized with these bacteria were limited. These results may have been affected by the COVID-19 pandemic. Further research is recommended., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2023 Romaen, Van Ussel, Van Rossem, Kenis, Ceulemans, Van Hoorenbeeck and Verhulst.)
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- 2023
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42. Validity of urges to smoke measures in predicting smoking relapse during treatment in primary care.
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Kotz D, van Rossem C, Viechtbauer W, Spigt M, and van Schayck OCP
- Subjects
- Humans, Primary Health Care, Recurrence, Smoking epidemiology, Smoking therapy, Varenicline therapeutic use, Smoking Cessation methods
- Abstract
In the context of smoking cessation treatment in primary care, identifying patients at the highest risk of relapse is relevant. We explored data from a primary care trial to assess the validity of two simple urges to smoke questions in predicting long-term relapse and their diagnostic value. Of 295 patients who received behavioural support and varenicline, 180 were abstinent at week 9. In this subgroup, we measured time spent with urges to smoke (TSU) and strength of urges to smoke (SUT; both scales 1 to 6 = highest). We used separate regression models with TSU or SUT as predictor and relapse from week 9-26 or week 9-52 as an outcome. We also calculated the sensitivity (SP), specificity and positive predictive values (PPV) of TSU and SUT in correctly identifying patients who relapsed at follow-up. The adjusted odds ratios (aOR) for predicting relapse from week 9-26 were 1.74 per point increase (95% CI = 1.05-2.89) for TSU and 1.59 (95% CI = 1.11-2.28) for SUT. The aORs for predicting relapse from week 9-52 were 2.41 (95% CI = 1.33-4.37) and 1.71 (95% CI = 1.14-2.56), respectively. Applying a cut-point of ≥3 on TSU resulted in SP = 97.1 and PPV = 70.0 in week 9-26, and SP = 98.8 and PPV = 90.0 in week 9-52. Applying a cut-point of ≥4 on SUT resulted in SP = 99.0 and PPV = 85.7 in week 9-26, and SP = 98.8 and PPV = 85.7 in week 9-52. Both TSU and SUT were valid predictors of long-term relapse in patients under smoking cessation treatment in primary care. These simple questions may be useful to implement in primary care.Trial registration: Dutch Trial Register (NTR3067)., (© 2021. The Author(s).)
- Published
- 2021
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43. Normal inflammatory markers and acute appendicitis: a national multicentre prospective cohort analysis.
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de Jonge J, Scheijmans JCG, van Rossem CC, van Geloven AAW, Boermeester MA, and Bemelman WA
- Subjects
- Acute Disease, Adult, Biomarkers, C-Reactive Protein analysis, Cohort Studies, Humans, Leukocyte Count, Prospective Studies, Retrospective Studies, Sensitivity and Specificity, Appendicitis diagnosis, Appendicitis surgery
- Abstract
Purpose: For the diagnosis of acute appendicitis, the combination of clinical and laboratory variables achieves high diagnostic accuracy. Nevertheless, appendicitis can present with normal laboratory tests of inflammation. The aim of this study was to investigate the incidence of normal inflammatory markers in patients operated for acute appendicitis., Methods: This is an analysis of data from a prospective, multicentre SNAPSHOT cohort study of patients with suspected acute appendicitis. Only patients with histopathologically proven acute appendicitis were included. Adult patients with acute appendicitis and normal preoperative inflammatory markers were explored further in terms of abdominal complaints, preoperative imaging results and intraoperative assessment of the degree of inflammation and compared to those with elevated inflammatory markers., Results: Between June and July 2014, 1303 adult patients with histopathologically proven acute appendicitis were included. In only 23 of 1303 patients (1.8%) with proven appendicitis, both preoperative white blood cell count and C-reactive protein levels were normal. Migration of pain was reported less frequently in patients with normal inflammatory markers compared to those with elevated inflammatory marker levels (17.4% versus 43.0%, p = 0.01). Characteristics like fever, duration of symptoms and localized peritonitis were comparable. Only 4 patients with normal inflammatory markers (0.3% overall) had complicated appendicitis at histopathological evaluation., Conclusion: Combined normal WBC and CRP levels are seen in about 2 per 100 patients with confirmed acute appendicitis and can, although rarely, be found in patients with complicated appendicitis.
- Published
- 2021
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44. Appendicular neoplasms and consequences in patients undergoing surgery for suspected acute appendicitis.
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Bolmers MDM, de Jonge J, van Rossem CC, van Geloven AAW, and Bemelman WA
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- Acute Disease, Appendectomy, Humans, Prospective Studies, Appendicitis diagnosis, Appendicitis surgery, Appendix, Laparoscopy, Neuroendocrine Tumors surgery
- Abstract
Introduction: In patients treated with an appendectomy for acute appendicitis, the specimen is generally sent for histological evaluation. In an era of increasing non-operative treatment for acute appendicitis, it is important to know the incidence, the diagnostic accuracy, and treatment consequences of appendicular neoplasms that are found in acute appendicitis. We hypothesize that pre- and intra-operative parameters might predict an appendicular neoplasm., Methods: Data was used from our previous prospective observational cohort study. All patients undergoing surgery for suspected acute appendicitis were included. The primary outcome was the incidence of appendicular neoplasms in patients operated for acute appendicitis. Secondary outcomes were pre-operative diagnostics and imaging outcomes, intra-operative surgical judgment, and postoperative management and outcome. Possible predictors of an appendicular neoplasm were identified and used in multivariable logistic regression. Patients with an appendicular neoplasm were followed for 3 years after initial appendectomy., Results: A total of 1975 patients underwent surgery for suspected acute appendicitis and in 98.3% (1941/1975) the appendix was removed. In 1.5% (30/1941) of these patients, an appendicular neoplasm was found. Among the malignant neoplasms, the majority were grade 1 neuroendocrine tumors (NET) in 65% (13/20). On pre-operative imaging, there was no suspicion of malignancy. In three cases, there was an intra-operative suspicion of malignancy. Multivariable analysis showed only age as an independent predictor for appendicular neoplasms. No recurrent or new malignancy was found during follow-up., Discussion: The incidence of appendicular neoplasm in patients undergoing an acute appendectomy is very low and clinical risk factors could not be identified.
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- 2020
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45. [Revised guideline for acute appendicitis. Amendments to diagnostics and treatment].
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Bom WJ, Knaapen M, Gorter RR, and van Rossem CC
- Subjects
- Acute Disease, Adolescent, Adult, Anti-Bacterial Agents therapeutic use, Appendectomy methods, Child, Child, Preschool, Female, Humans, Laparoscopy, Magnetic Resonance Imaging, Male, Practice Guidelines as Topic, Pregnancy, Ultrasonography, Young Adult, Appendicitis diagnostic imaging, Appendicitis therapy
- Abstract
Recently, the revised guideline 'Guideline for diagnostics and treatment of acute appendicitis' was published by the Dutch Surgical Society. A patient with limited clinical symptoms and low suspicion of appendicitis can be assessed again at a later time, during which ultrasound diagnostics can be repeated. Following an inconclusive ultrasound scan in children who possibly have appendicitis, it is no longer recommended to perform diagnostic laparoscopy; rather, MRI diagnostics are indicated. In young adults with possible appendicitis, in whom a diagnosis cannot be established using ultrasound, the advice is to use MRI diagnostics instead of CT imaging; this particularly applies to women of child-bearing age. For patients with appendicitis an appendectomy remains the recommended treatment, although one can consider treating adults with suspected simple appendicitis with antibiotics alone. It is important that this decision is made in consultation with the patient. Laparoscopic appendectomy reduces the number of wound infections and admission length, and is therefore usually preferred over open method appendectomy. If a patient with appendicitis is 24-28 weeks pregnant,consultation with a specialist centre is indicated regarding the obstetric management and possibly referral.
- Published
- 2020
46. [Acute appendicitis: treatment in accordance with new guideline].
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Bom WJ, Knaapen M, Gorter RR, and van Rossem CC
- Subjects
- Acute Disease, Aged, Female, Humans, Male, Practice Guidelines as Topic, Young Adult, Anti-Bacterial Agents therapeutic use, Appendectomy adverse effects, Appendicitis diagnosis, Appendicitis therapy
- Abstract
In this clinical lesson we present two patient cases. A 66-year-old female patient with a clinical, biochemical and radiological suspicion of complex appendicitis. The patient undergoes an appendectomy and post-operative recovery is beset with complications. The other case involves a 24-year-old male patient with suspected simple appendicitis. He is successfully treated with antibiotics and without surgery. By using these patients as examples, we discuss the revised clinical guideline for diagnosing and treating acute appendicitis. Besides that, we also discuss the differentiation between simple and complex appendicitis and how this can influence the treatment plan.
- Published
- 2020
47. [A man with abdominal pain, diarrhoea and rectal bleeding].
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Oosterwijk AJM, van den Berg JW, and van Rossem CC
- Subjects
- Abdominal Pain surgery, Appendiceal Neoplasms complications, Colectomy, Colonoscopy, Diarrhea surgery, Gastrointestinal Hemorrhage surgery, Humans, Intussusception complications, Intussusception surgery, Male, Middle Aged, Mucocele complications, Mucocele surgery, Rectal Diseases surgery, Vomiting surgery, Abdominal Pain etiology, Adenocarcinoma, Mucinous complications, Cecal Neoplasms complications, Diarrhea etiology, Gastrointestinal Hemorrhage etiology, Ileal Neoplasms complications, Rectal Diseases etiology, Vomiting etiology
- Abstract
A 49-year-old man came to the emergency room with abdominal pain, vomiting, diarrhoea and rectal bleeding. Both colonoscopy and CT of the abdomen showed cecocolic intussusception caused by an appendiceal mucocele. An ileocecal resection was performed via a laparoscopic approach and microscopy of the tissue showed a low-grade mucinous neoplasm.
- Published
- 2018
48. Effectiveness of intensive practice nurse counselling versus brief general practitioner advice, both combined with varenicline, for smoking cessation: a randomized pragmatic trial in primary care.
- Author
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van Rossem C, Spigt M, Viechtbauer W, Lucas AEM, van Schayck OCP, and Kotz D
- Subjects
- Female, General Practitioners, Humans, Male, Middle Aged, Netherlands, Nicotinic Agonists therapeutic use, Nurses, Smoking therapy, Treatment Outcome, Advanced Practice Nursing methods, Counseling methods, General Practice methods, Primary Health Care methods, Smoking Cessation methods, Varenicline therapeutic use
- Abstract
Aims: To study the effectiveness of intensive counselling by a practice nurse (PN) versus brief advice by a general practitioner (GP), each combined with pharmacotherapy, for 6 months' tobacco abstinence (primary outcome). Secondary outcomes included 12-month abstinence, medication adherence and incremental costs per life-year gained., Design: A multi-site (n = 10), two-group, parallel, pragmatic randomized controlled trial., Setting: A network of primary health-care centres in the Netherlands., Participants: A total of 295 adult daily smokers (mean age = 48 years; mean cigarettes/day = 19)., Intervention and Comparator: Patients were randomized to receive individual counselling by a practice nurse (PN) (n = 149) or brief advice by a general practitioner (GP) (146). All patients received 12 weeks of open-label varenicline., Measurements: The primary outcome was prolonged biochemically validated abstinence from weeks 9 to 26 after treatment initiation. Secondary outcomes included abstinence from weeks 9 to 52, good dosing adherence (> 80% days taken) and incremental costs per life-year gained., Findings: Abstinence rates in the PN versus GP groups were 32.2% (n = 48) versus 39.0% [n = 57; odds ratio (OR) = 0.71; 95% confidence interval (CI) = 0.44-1.16] from weeks 9 to 26 and 25.5% (n = 38) versus 28.8% (n = 42; OR = 0.84, 95% CI = 0.50-1.43) from weeks 9 to 52, respectively. Values of the Bayes factor indicated that the PN and GP were equally effective. Good dosing adherence was significantly lower in the PN (45.5%, n = 56/123) than in the GP group (62.0%, n = 75/121; OR = 0.45, 95% CI = 0.26-0.77), and the incremental costs per life-year gained were -€416.10., Conclusions: Among people seeking help to stop smoking from their general practice, one-off brief advice from a general practitioner appears to be as effective as several sessions of behavioural support from a practice nurse when smoking cessation medication is provided., (© 2017 Society for the Study of Addiction.)
- Published
- 2017
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49. Smoking cessation in primary care: Exploration of barriers and solutions in current daily practice from the perspective of smokers and healthcare professionals.
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van Rossem C, Spigt MG, Kleijsen JR, Hendricx M, van Schayck CP, and Kotz D
- Subjects
- Adult, Aged, Attitude of Health Personnel, Female, Focus Groups, Health Knowledge, Attitudes, Practice, Humans, Interviews as Topic, Male, Middle Aged, Netherlands, Nicotinic Agonists therapeutic use, Nurses psychology, Physician-Patient Relations, Qualitative Research, Tobacco Use Cessation Devices, General Practice, Patient Acceptance of Health Care, Practice Patterns, Physicians', Primary Health Care, Smoking Cessation methods
- Abstract
Background: Evidence based recommendations for smoking cessation are not followed in routine primary care. A better understanding is needed why smoking cessation treatment is still underutilized., Objectives: To explore barriers and solutions of smoking cessation treatment, from the perspective of smokers and healthcare professionals in Dutch primary care., Methods: Focus groups were conducted with 14 smokers (smokers and ex-smokers) and semi-structured individual interviews with nine healthcare professionals (general practitioners and practice nurses). Data was analysed using the Constant Comparative Method., Results: Barriers that prevented successful smoking cessation treatment were the lack of awareness regarding the available smoking cessation treatments at the healthcare centre among smokers and the resistance against preventive tasks among healthcare professionals. Nonetheless, general practitioners (GPs) did not fear jeopardizing the doctor-patient relationship by discussing smoking. Quitting was regarded as the smokers' own responsibility and GPs felt that merely using medication was no guarantee for successful quitting. Even so, practice nurses and smokers preferred medication use. Proposed solutions were that GPs should advise smokers to quit, whereas someone else should deliver intensive behavioural support, preferably the practice nurse., Conclusion: Smokers and healthcare professionals seem to wait for each other to start smoking cessation. GPs should know that they could discuss smoking cessation with every patient without jeopardizing the doctor-patient relationship, preferably followed by referral to a practice nurse for intensive behavioural support. Furthermore, more patients should know that they could receive pharmacological treatment as well as behavioural support for smoking cessation in their healthcare centre.
- Published
- 2015
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50. Sarcomatous degeneration in fibrous dysplasia of the rib cage.
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Van Rossem C, Pauwels P, Somville J, Camerlinck M, Bogaerts P, and Van Schil PE
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- Bone Neoplasms diagnosis, Fibrous Dysplasia, Polyostotic diagnosis, Humans, Male, Middle Aged, Osteosarcoma diagnosis, Bone Neoplasms complications, Fibrous Dysplasia, Polyostotic complications, Osteosarcoma complications, Ribs
- Abstract
Malignant degeneration in fibrous dysplasia is a rare occurrence. Most cases are reported in polyostotic fibrous dysplasia with predisposition of the femur, tibia, maxilla, and mandible. The most commonly observed malignant tumors are osteosarcoma, fibrosarcoma, and chondrosarcoma. We describe a case of a low-grade osteosarcoma occurring in polyostotic fibrous dysplasia of the rib cage in a 50-year-old man., (Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
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