18 results on '"Van Rensburg, Christa Janse"'
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2. Differences in Daytime vs. Night-time Travel Stress and Recovery as Measured by Heart Rate Variability: 725 May 29 4:45 PM - 5:00 PM
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van Rensburg, Christa Janse, Grant, Catharina C., van Rensburg, Audrey Jansen, Ramagole, Dimakatso A., and Kalmeier, Gehart
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- 2019
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3. Ankylosing Spondylitis: How Important is Exercise as Part of Management: 467 Board #305 May 29 11:00 AM - 12:30 PM
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van Rensburg, Christa Janse, van Rensburg, Audrey Jansen, Grant, Catharina C., and Ramagole, Dimakatso A.
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- 2019
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4. La calidad de sueño afecta la calidad de vida relacionada con la salud en atletas jóvenes durante una competición
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Gajardo Burgos, Rubén, Monrroy Uarac, Manuel, Belmar Arriagada, Hellen, Bascour Sandoval, Claudio, van Rensburg, Christa Janse, Gajardo Burgos, Rubén, Monrroy Uarac, Manuel, Belmar Arriagada, Hellen, Bascour Sandoval, Claudio, and van Rensburg, Christa Janse
- Abstract
Cross-sectional, analytical study that examined the link between sleep quality (SQ) and health-related quality of life (HRQOL) in young athletes in a sports competition. SQ was measured through the Pittsburgh Sleep Quality Index (PSQI), and HRQOL through the SF36 v2 (SF36v2) short-form health survey in 71 young athletes (39 men; mean age 16.9, SD = 1.2 years; mean 6.5, SD = 3.2 years in sports and mean 10.8, SD = 3.3 hours of weekly training) on the day prior to a competition. When comparing the athletes according to SQ (poor SQ > 5 PSQI), significant differences were found (p < .05) in HRQOL in the domains bodily pain, general health, vitality, social function, emotional role and mental health, but not in the domains bodily function and physical role. Our results suggest poor SQ is associated with a worse perception of HRQOL in young athletes in competition., Estudio analítico transversal que examinó el vínculo entre la calidad del sueño (SQ) y la calidad de vida relacionada con la salud (HRQOL) en jóvenes atletas en una competencia deportiva. SQ se midió a través del índice de calidad del sueño de Pittsburgh (PSQI) y HRQOL a través de la encuesta de salud de formato corto SF36 v2 (SF36v2) en 71 atletas jóvenes (39 hombres; edad media 16,9, SD = 1,2 años; promedio 6,5, SD 3,2 años de práctica deportiva; y promedio 10,8, SD = 3,3 horas de entrenamiento semanal) el día anterior a una competición. Al comparar los atletas según SQ (SQ deficiente > 5 PSQI), fueron encontradas diferencias significativas (p < ,05) en la HRQOL en los dominios dolor corporal, salud general, vitalidad, función social, rol emocional y salud mental, pero no en los dominios función corporal y rol físico. Nuestros resultados sugieren que un SQ deficiente se asocia con una peor percepción de la HRQOL en atletas jóvenes en competencia.
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- 2023
5. Sport and exercise medicine in South Africa
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Zondi, Phathokuhle, van Rensburg, Christa Janse, and Patricios, Jon
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- 2015
6. Injury And Illness During A Four-day High School Netball Tournament: A Cross-sectional Study Of 1357 Players
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van Rensburg, Christa Janse, primary, Blanco, Jessica Hamuy, additional, van Rensburg, Audrey Jansen, additional, Coetzer, Jeanette, additional, and Botha, Tanita, additional
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- 2022
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7. Health conditions among retired elite rugby players: a scoping review.
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Le Roux, Johan, Anema, Flo, van Rensburg, Christa Janse, Kerkhoffs, Gino, and Gouttebarge, Vincent
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- 2023
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8. MRI findings in chronic exertional compartment syndrome of the forearm: Using signal intensity ratio as a diagnostic tool
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Badenhorst, Jacques, primary, Velleman, Mark, additional, van Rensburg, Audrey Jansen, additional, Botha, Tanita, additional, van der Walt, Nikki, additional, and van Rensburg, Christa Janse, additional
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- 2021
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9. Endurance Training and Heart Rate Variability (HRV): 2155: Board #32 June 2 2:00 PM - 3:30 PM
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van Rensburg, Christa Janse, Grant, Catharina C., and Fletcher, Lizelle
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- 2011
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10. The Prescription Of Exercise To Counter Autonomic Dysfunction In Rheumatoid Arthritis Patients: 2118: Board #313 June 2 9:00 AM - 10:30 AM
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van Rensburg, Christa Janse, Fletcher, Lizelle, and C. Grant, Catharina
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- 2011
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11. Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: Analysis by the Pharmachild Safety Adjudication Committee
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Immuno/reuma patientenzorg, Child Health, Infectieziekten patientenzorg, Infection & Immunity, Cluster B, Immuno/reuma onderzoek 1 (Vastert), Immunologie/Reumatologie, Regenerative Medicine and Stem Cells, Onderzoek, Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Huppertz, Hans Iko, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Rygg, Marite, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, Ruperto, Nicolino, Cuttica, Ruben, Garay, Stella Maris, Brunner, Jurgen, Emminger, Wolfgang, Appenzeller, Simone, Len, Claudio, Saad Magalhaes, Claudia, Telcharova-Mihaylovska, Albena, Harjacek, Miroslav, Jelusic, Marija, Estmann, Anne, Nielsen, Susan, Herrera Mora, Cristina, Gervais, Elisabeth, Koné-Paut, Isabelle, Quartier, Pierre, Foeldvari, Ivan, Lutz, Thomas, Minden, Kirsten, Tzaribachev, Nikolay, Trachana, Maria, Tsitsami, Elena, Vougiouka, Olga, Orban, Ilonka, Harel, Liora, Hashkes, Philip, Uziel, Yosef, Cimaz, Rolando, Civino, Adele, Consolini, Rita, D'Angelo, Gianfranco, De Benedetti, Fabrizio, Filocamo, Giovanni, Fueri, Elena, Gallizzi, Romina, Maggio, Maria Cristina, Magnolia, Maria Greca, Miniaci, Angela, Montin, Davide, Olivieri, Alma Nunzia, Pastore, Serena, Rigante, Donato, Zulian, Francesco, Rumba-Rozenfelde, Ingrida, Stanevicha, Valda, Panaviene, Violeta, Rodriguez Lozano, Ana Luisa, Rubio-Perez, Nadina, Vega Cornejo, Gabriel, Hoppenreijs, Esther, Kamphuis, Sylvia, Flato, Berit, Nordal, Ellen Berit, Abdwani, Reem, Miraval, Tatiana, Paz Gastanaga, Maria Eliana, Smolewska, Elzbieta, Ailioaie, Constantin, Cochino, Alexis Virgil, Laday, Matilda, Lazar, Calin, Alexeeva, Ekaterina, Chasnyk, Vyacheslav, Keltsev, Vladimir, Suwairi, Wafaa Mohammed Saad, Vijatov-Djuric, Gordana, Vojinovic, Jelena, Arkachaisri, Thaschawee, Koskova, Elena, Avcin, Tadej, Ally, Mahmood, Van Rensburg, Christa Janse, Louw, Ingrid, Lopez, Jordi Anton, Boteanu, Alina Lucica, Calvo Penades, Inmaculada, De Inocencio, Jaime, Mesa-Del-Castillo, Pablo, Moreno, Estefania, Remesal, Agustin, Hofer, Michael, Gok, Faysal, Ozen, Seza, Ramanan, Athimalaipet, Pallotti, Chiara, Villa, Luca, Immuno/reuma patientenzorg, Child Health, Infectieziekten patientenzorg, Infection & Immunity, Cluster B, Immuno/reuma onderzoek 1 (Vastert), Immunologie/Reumatologie, Regenerative Medicine and Stem Cells, Onderzoek, Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Huppertz, Hans Iko, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Rygg, Marite, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, Ruperto, Nicolino, Cuttica, Ruben, Garay, Stella Maris, Brunner, Jurgen, Emminger, Wolfgang, Appenzeller, Simone, Len, Claudio, Saad Magalhaes, Claudia, Telcharova-Mihaylovska, Albena, Harjacek, Miroslav, Jelusic, Marija, Estmann, Anne, Nielsen, Susan, Herrera Mora, Cristina, Gervais, Elisabeth, Koné-Paut, Isabelle, Quartier, Pierre, Foeldvari, Ivan, Lutz, Thomas, Minden, Kirsten, Tzaribachev, Nikolay, Trachana, Maria, Tsitsami, Elena, Vougiouka, Olga, Orban, Ilonka, Harel, Liora, Hashkes, Philip, Uziel, Yosef, Cimaz, Rolando, Civino, Adele, Consolini, Rita, D'Angelo, Gianfranco, De Benedetti, Fabrizio, Filocamo, Giovanni, Fueri, Elena, Gallizzi, Romina, Maggio, Maria Cristina, Magnolia, Maria Greca, Miniaci, Angela, Montin, Davide, Olivieri, Alma Nunzia, Pastore, Serena, Rigante, Donato, Zulian, Francesco, Rumba-Rozenfelde, Ingrida, Stanevicha, Valda, Panaviene, Violeta, Rodriguez Lozano, Ana Luisa, Rubio-Perez, Nadina, Vega Cornejo, Gabriel, Hoppenreijs, Esther, Kamphuis, Sylvia, Flato, Berit, Nordal, Ellen Berit, Abdwani, Reem, Miraval, Tatiana, Paz Gastanaga, Maria Eliana, Smolewska, Elzbieta, Ailioaie, Constantin, Cochino, Alexis Virgil, Laday, Matilda, Lazar, Calin, Alexeeva, Ekaterina, Chasnyk, Vyacheslav, Keltsev, Vladimir, Suwairi, Wafaa Mohammed Saad, Vijatov-Djuric, Gordana, Vojinovic, Jelena, Arkachaisri, Thaschawee, Koskova, Elena, Avcin, Tadej, Ally, Mahmood, Van Rensburg, Christa Janse, Louw, Ingrid, Lopez, Jordi Anton, Boteanu, Alina Lucica, Calvo Penades, Inmaculada, De Inocencio, Jaime, Mesa-Del-Castillo, Pablo, Moreno, Estefania, Remesal, Agustin, Hofer, Michael, Gok, Faysal, Ozen, Seza, Ramanan, Athimalaipet, Pallotti, Chiara, and Villa, Luca
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- 2020
12. Infographic. General guidance for the prevention of illness in athletes
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Schwellnus, Martin, primary, Soligard, Torbjørn, additional, Alonso, Juan Manuel, additional, Bahr, Roald, additional, Clarsen, Ben, additional, Dijkstra, H Paul, additional, Gabbett, Tim J, additional, Gleeson, Michael, additional, Hägglund, Martin, additional, Hutchinson, Mark R, additional, Van Rensburg, Christa Janse, additional, Meeusen, Romain, additional, Orchard, John W, additional, Pluim, Babette M, additional, Raftery, Martin, additional, Budgett, Richard, additional, and Engebretsen, Lars, additional
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- 2016
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13. How much is too much? (Part 1) International Olympic Committee consensus statement on load in sport and risk of injury.
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Soligard, Torbjørn, Schwellnus, Martin, Alonso, Juan-Manuel, Bahr, Roald, Clarsen, Ben, Dijkstra, H. Paul, Gabbett, Tim, Gleeson, Michael, Hägglund, Martin, Hutchinson, Mark R., van Rensburg, Christa Janse, Khan, Karim M., Meeusen, Romain, Orchard, John W., Pluim, Babette M., Raftery, Martin, Budgett, Richard, and Engebretsen, Lars
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SPORTS injuries risk factors ,ATHLETE training ,VIGILANCE (Psychology) ,ATHLETES' health - Published
- 2016
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14. How much is too much? (Part 2) International Olympic Committee consensus statement on load in sport and risk of illness.
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Schwellnus, Martin, Soligard, Torbjørn, Alonso, Juan-Manuel, Bahr, Roald, Clarsen, Ben, Dijkstra, H. Paul, Gabbett, Tim J., Gleeson, Michael, Hägglund, Martin, Hutchinson, Mark R., Van Rensburg, Christa Janse, Meeusen, Romain, Orchard, John W., Pluim, Babette M., Raftery, Martin, Budgett, Richard, and Engebretsen, Lars
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SPORTS injuries risk factors ,ATHLETE training ,OVERTRAINING ,ATHLETES' health - Published
- 2016
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15. Infographic. General guidance for the prevention of illness in athletes.
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Schwellnus, Martin, Soligard, Torbjørn, Alonso, Juan Manuel, Bahr, Roald, Clarsen, Ben, Dijkstra, H. Paul, Gabbett, Tim J., Gleeson, Michael, Hägglund, Martin, Hutchinson, Mark R., Van Rensburg, Christa Janse, Meeusen, Romain, Orchard, John W., Pluim, Babette M., Raftery, Martin, Budgett, Richard, and Engebretsen, Lars
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INFORMATION design ,SPORTS injury prevention ,ATHLETES' health ,ATHLETES ,ATHLETE training ,HUMAN sexuality - Published
- 2017
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16. Die uitwerking van 'n intensiewe afrigtingsprogram op die kardiostresindeks.
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du Toit, Peet J., Gibson, Alan St. Clair, Wood, Paola, Grant, Catherina C., Grimes, Kristopher R., Tope, Avinash M., van Rensburg, Christa Janse, van Rooyen, Johannes M., Mckune, Andrew, Nortjé, Evangeline, Fletcher, Lizelle, Ferreira, Ronel, Joubert, Annie, and Stander, Andre
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Armed service recruits are faced with many stressors, including a strenuous training regimen that may have an impact on their physiological functioning. The Cardio Stress Index (CSI) is a noninvasive marker of the stress that the heart is experiencing. The aim of the study was to test the physiological impact of 20 weeks of intense training of armed service recruits, using CSI as a noninvasive biomarker of cardiac stress. Armed service recruits are faced with many stressors, including a strenuous training regimen that may have an impact on their physiological functioning. The CSI is a noninvasive marker of the stress that the heart is experiencing. The calculation of the CSI is based on the duration of vascular excitation (QRS duration), heart rate, heart rhythm and standard deviation of the duration of time between each successive cardiac cycle (RR-interval). The aim of the present study was to test the physiological impact of 20 weeks of strenuous training of armed service recruits, using CSI as a noninvasive biomarker of cardiac stress. Experiments were conducted at three points in time (weeks 1, 12, 20) during the basic military training of armed service recruits (n = 202, males = 115, females = 87), aged between 18 and 24 years. Variables measured include: Resting CSI, heart rate and blood pressure. Data analysis was performed, using paired t-tests for pairwise comparisons of week 1 (baseline) with week 12; week 12 with week 20; and week 1 with week 20. The average CSI and heart rate remained within normal values for male participants on all three testing occasions. However, baseline readings for females were significantly higher during week 1. There was an overall decrease in the CSI in the 20 week time frame. From this study it seems as if the CSI measurement is a noninvasive method to establish the effects of training on the health of the heart. [ABSTRACT FROM AUTHOR]
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- 2014
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17. Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee
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Giancane G1, Swart JF2, Castagnola E3, Groll AH4, Horneff G5, 6, Huppertz HI7, Lovell DJ8, Wolfs T2, Herlin T9, Dolezalova P10, Sanner H11, Susic G13, Sztajnbok F14, Maritsi D15, Constantin T16, Vargova V17, Sawhney S18, Rygg M19, K Oliveira S21, Cattalini M22, Bovis F1, Bagnasco F1, Pistorio A23, Martini A24, Wulffraat N2, Ruperto N25, Paediatric Rheumatology International Trials Organisation (PRINTO). Cuttica R, Garay SM, Brunner J, Emminger W, Appenzeller S, Len C, Saad Magalhaes C, Telcharova-Mihaylovska A, Harjacek M, Jelusic M, Estmann A, Nielsen S, Herrera Mora C, Gervais E, Koné-Paut I, Quartier P, Foeldvari I, Horneff G, Lutz T, Minden K, Tzaribachev N, Trachana M, Tsitsami E, Vougiouka O, Orban I, Harel L, Hashkes P, Uziel Y, Cimaz R, Civino A, Consolini R, D'Angelo G, De Benedetti F, Filocamo G, Fueri E, Gallizzi R, Maggio MC, Magnolia MG, Miniaci A, Montin D, Olivieri A. N., Pastore S, Rigante D, Zulian F, Rumba-Rozenfelde I, Stanevicha V, Panaviene V, Rodriguez Lozano AL, Rubio-Perez N, Vega Cornejo G, Hoppenreijs E, Kamphuis S, Flato B, Nordal EB, Abdwani R, Miraval T, Paz Gastanaga ME, Smolewska E, Ailioaie C, Cochino AV, Laday M, Lazar C, Alexeeva E, Chasnyk V, Keltsev V, Suwairi WMS, Vijatov-Djuric G, Vojinovic J, Arkachaisri T, Koskova E, Avcin T, Ally M, Van Rensburg CJ, Louw I, Lopez JA, Boteanu AL, Calvo Penades I, De Inocencio J, Mesa-Del-Castillo P, Moreno E, Remesal A, Hofer M, Gok F, Ozen S, Ramanan A, Pallotti C, Villa L., Giancane, G1, Swart, Jf2, Castagnola, E3, Groll, Ah4, Horneff, G5, Huppertz, Hi7, Lovell, Dj8, Wolfs, T2, Herlin, T9, Dolezalova, P10, Sanner, H11, Susic, G13, Sztajnbok, F14, Maritsi, D15, Constantin, T16, Vargova, V17, Sawhney, S18, Rygg, M19, K Oliveira, S21, Cattalini, M22, Bovis, F1, Bagnasco, F1, Pistorio, A23, Martini, A24, Wulffraat, N2, Ruperto, N25, Paediatric Rheumatology International Trials Organisation (PRINTO)., Cuttica R, Garay, Sm, Brunner, J, Emminger, W, Appenzeller, S, Len, C, Saad Magalhaes, C, Telcharova-Mihaylovska, A, Harjacek, M, Jelusic, M, Estmann, A, Nielsen, S, Herrera Mora, C, Gervais, E, Koné-Paut, I, Quartier, P, Foeldvari, I, Horneff, G, Lutz, T, Minden, K, Tzaribachev, N, Trachana, M, Tsitsami, E, Vougiouka, O, Orban, I, Harel, L, Hashkes, P, Uziel, Y, Cimaz, R, Civino, A, Consolini, R, D'Angelo, G, De Benedetti, F, Filocamo, G, Fueri, E, Gallizzi, R, Maggio, Mc, Magnolia, Mg, Miniaci, A, Montin, D, Olivieri, A. N., Pastore, S, Rigante, D, Zulian, F, Rumba-Rozenfelde, I, Stanevicha, V, Panaviene, V, Rodriguez Lozano, Al, Rubio-Perez, N, Vega Cornejo, G, Hoppenreijs, E, Kamphuis, S, Flato, B, Nordal, Eb, Abdwani, R, Miraval, T, Paz Gastanaga, Me, Smolewska, E, Ailioaie, C, Cochino, Av, Laday, M, Lazar, C, Alexeeva, E, Chasnyk, V, Keltsev, V, Suwairi, Wm, Vijatov-Djuric, G, Vojinovic, J, Arkachaisri, T, Koskova, E, Avcin, T, Ally, M, Van Rensburg, Cj, Louw, I, Lopez, Ja, Boteanu, Al, Calvo Penades, I, De Inocencio, J, Mesa-Del-Castillo, P, Moreno, E, Remesal, A, Hofer, M, Gok, F, Ozen, S, Ramanan, A, Pallotti, C, Villa, L., Giancane, Gabriella, Swart, Joost F, Castagnola, Elio, Groll, Andreas H, Horneff, Gerd, Huppertz, Hans-Iko, Lovell, Daniel J, Wolfs, Tom, Herlin, Troel, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tama, Vargova, Veronika, Sawhney, Sujata, Rygg, Marite, K Oliveira, Sheila, Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, Ruperto, Nicolino, Cuttica, Ruben, Garay, Stella Mari, Brunner, Jurgen, Emminger, Wolfgang, Appenzeller, Simone, Len, Claudio, Saad Magalhaes, Claudia, Telcharova-Mihaylovska, Albena, Harjacek, Miroslav, Jelusic, Marija, Estmann, Anne, Nielsen, Susan, Herrera Mora, Cristina, Gervais, Elisabeth, Koné-Paut, Isabelle, Quartier, Pierre, Foeldvari, Ivan, Lutz, Thoma, Minden, Kirsten, Tzaribachev, Nikolay, Trachana, Maria, Tsitsami, Elena, Vougiouka, Olga, Orban, Ilonka, Harel, Liora, Hashkes, Philip, Uziel, Yosef, Cimaz, Rolando, Civino, Adele, Consolini, Rita, D'Angelo, Gianfranco, De Benedetti, Fabrizio, Filocamo, Giovanni, Fueri, Elena, Gallizzi, Romina, Maggio, Maria Cristina, Magnolia, Maria Greca, Miniaci, Angela, Montin, Davide, Olivieri, Alma Nunzia, Pastore, Serena, Rigante, Donato, Zulian, Francesco, Rumba-Rozenfelde, Ingrida, Stanevicha, Valda, Panaviene, Violeta, Rodriguez Lozano, Ana Luisa, Rubio-Perez, Nadina, Vega Cornejo, Gabriel, Hoppenreijs, Esther, Kamphuis, Sylvia, Flato, Berit, Nordal, Ellen Berit, Abdwani, Reem, Miraval, Tatiana, Paz Gastanaga, Maria Eliana, Smolewska, Elzbieta, Ailioaie, Constantin, Cochino, Alexis-Virgil, Laday, Matilda, Lazar, Calin, Alexeeva, Ekaterina, Chasnyk, Vyacheslav, Keltsev, Vladimir, Suwairi, Wafaa Mohammed Saad, Vijatov-Djuric, Gordana, Vojinovic, Jelena, Arkachaisri, Thaschawee, Koskova, Elena, Avcin, Tadej, Ally, Mahmood, Van Rensburg, Christa Janse, Louw, Ingrid, Lopez, Jordi Anton, Boteanu, Alina Lucica, Calvo Penades, Inmaculada, De Inocencio, Jaime, Mesa-Del-Castillo, Pablo, Moreno, Estefania, Remesal, Agustin, Hofer, Michael, Gok, Faysal, Ozen, Seza, Ramanan, Athimalaipet, Pallotti, Chiara, Villa, Luca, and Pediatrics
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Male ,lcsh:Diseases of the musculoskeletal system ,Biologic ,Paediatrics: 760 [VDP] ,Artritis infecciosa ,MedDRA ,Infants malalts ,Arthritis ,Severity of Illness Index ,Hospital patients ,Cohort Studies ,Pharmacovigilance ,0302 clinical medicine ,030212 general & internal medicine ,Registries ,Child ,Biologics ,Immunosuppressive therapy ,Infections ,Juvenile idiopathic arthritis ,Opportunistic ,biologics ,immunosuppressive therapy ,infections ,juvenile idiopathic arthritis ,opportunistic ,Barneleddgikt ,3. Good health ,Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA ,Antirheumatic Agents ,Child, Preschool ,Cohort ,Pediatric Infectious Disease ,Female ,Infection ,Research Article ,medicine.medical_specialty ,Tuberculosis ,juvenil idiopathic arthritis ,Opportunistic Infections ,Herpes Zoster ,03 medical and health sciences ,Immunocompromised Host ,Juvenile idiopathic arthriti ,Internal medicine ,medicine ,Humans ,book ,030203 arthritis & rheumatology ,Malalts hospitalitzats ,Immunosupressió ,business.industry ,Sick children ,medicine.disease ,Rheumatology ,Arthritis, Juvenile ,Infectious arthritis ,Pediatri: 760 [VDP] ,Orthopedic surgery ,Opportunistiske infeksjoner ,book.journal ,lcsh:RC925-935 ,business ,Infeccions oportunistes ,Immunosuppression - Abstract
Background: To derive a list of opportunistic infections (OI) through the analysis of the juvenile idiopathic arthritis (JIA) patients in the Pharmachild registry by an independent Safety Adjudication Committee (SAC). Methods: The SAC (3 pediatric rheumatologists and 2 pediatric infectious disease specialists) elaborated and approved by consensus a provisional list of OI for use in JIA. Through a 5 step-procedure, all the severe and serious infections, classified as per MedDRA dictionary and retrieved in the Pharmachild registry, were evaluated by the SAC by answering six questions and adjudicated with the agreement of 3/5 specialists. A final evidence-based list of OI resulted by matching the adjudicated infections with the provisional list of OI. Results: A total of 772 infectious events in 572 eligible patients, of which 335 serious/severe/very severe non-OI and 437 OI (any intensity/severity), according to the provisional list, were retrieved. Six hundred eighty-two of 772 (88.3%) were adjudicated as infections, of them 603/682 (88.4%) as common and 119/682 (17.4%) as OI by the SAC. Matching these 119 opportunistic events with the provisional list, 106 were confirmed by the SAC as OI, and among them infections by herpes viruses were the most frequent (68%), followed by tuberculosis (27.4%). The remaining events were divided in the groups of non-OI and possible/patient and/or pathogen-related OI. Conclusions: We found a significant number of OI in JIA patients on immunosuppressive therapy. The proposed list of OI, created by consensus and validated in the Pharmachild cohort, could facilitate comparison among future pharmacovigilance studies. © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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- 2020
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18. MRI findings in chronic exertional compartment syndrome of the forearm: Using signal intensity ratio as a diagnostic tool.
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Badenhorst J, Velleman M, van Rensburg AJ, Botha T, van der Walt N, and van Rensburg CJ
- Abstract
Background: Chronic exertional compartment syndrome (CECS) of the forearm is a rare but important cause of morbidity amongst athletes involved in strenuous upper limb activities. The diagnosis remains challenging due to the absence of objective, reproducible diagnostic studies., Objectives: To assess and quantify signal intensity (SI) changes of involved muscles in patients with CECS of the forearm compared to healthy control subjects competing in similar sporting disciplines. Also, to objectively measure MRI SIs within muscle compartments when using a pre- and post-exercise regime and calculating a signal intensity ratio (SIR) between post- and pre-exercise studies., Method: The study retrospectively examined MRI scans of patients treated for CECS of the forearm and compared these to the MRI scans of asymptomatic high-level rowers. A specific, reproducible pre- and post-exercise MRI scanning protocol was utilised in both patient and control subjects between 2011 and 2020. Signal intensities were evaluated pre- and post-exercise in involved muscle groups and ratios were calculated., Results: A total of 86 SIs were measured (43 pre- and 43 post-exercise) in nine study participants (five patients and four controls). After post:pre-exercise comparisons, a statistically significant difference was found between control and patient groups ( p = 0.0010). The extensor carpi radialis, flexor digitorum profundus and flexor digitorum superficialis muscles were most commonly involved., Conclusion: This study confirms that significant SI changes are apparent in patients with CECS of the forearm when making use of a standardised pre- and post-exercise MRI protocol. Furthermore, SIR may be used to accurately diagnose CECS of the forearm., Competing Interests: The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article., (© 2021. The Authors.)
- Published
- 2021
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