19 results on '"Van Meer, Oene"'
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2. Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest
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Medische Staf Intensive Care, Team Medisch, Other research (not in main researchprogram), Suverein, Martje M., Delnoij, Thijs S.R., Lorusso, Roberto, Brandon Bravo Bruinsma, George J., Otterspoor, Luuk, Elzo Kraemer, Carlos V., Vlaar, Alexander P.J., van der Heijden, Joris J., Scholten, Erik, den Uil, Corstiaan, Jansen, Tim, van den Bogaard, Bas, Kuijpers, Marijn, Lam, Ka Yan, Montero Cabezas, José M., Driessen, Antoine H.G., Rittersma, Saskia Z.H., Heijnen, Bram G., Dos Reis Miranda, Dinis, Bleeker, Gabe, de Metz, Jesse, Hermanides, Renicus S., Lopez Matta, Jorge, Eberl, Susanne, Donker, Dirk W., van Thiel, Robert J., Akin, Sakir, van Meer, Oene, Henriques, José, Bokhoven, Karen C., Mandigers, Loes, Bunge, Jeroen J.H., Bol, Martine E., Winkens, Bjorn, Essers, Brigitte, Weerwind, Patrick W., Maessen, Jos G., van de Poll, Marcel C.G., Medische Staf Intensive Care, Team Medisch, Other research (not in main researchprogram), Suverein, Martje M., Delnoij, Thijs S.R., Lorusso, Roberto, Brandon Bravo Bruinsma, George J., Otterspoor, Luuk, Elzo Kraemer, Carlos V., Vlaar, Alexander P.J., van der Heijden, Joris J., Scholten, Erik, den Uil, Corstiaan, Jansen, Tim, van den Bogaard, Bas, Kuijpers, Marijn, Lam, Ka Yan, Montero Cabezas, José M., Driessen, Antoine H.G., Rittersma, Saskia Z.H., Heijnen, Bram G., Dos Reis Miranda, Dinis, Bleeker, Gabe, de Metz, Jesse, Hermanides, Renicus S., Lopez Matta, Jorge, Eberl, Susanne, Donker, Dirk W., van Thiel, Robert J., Akin, Sakir, van Meer, Oene, Henriques, José, Bokhoven, Karen C., Mandigers, Loes, Bunge, Jeroen J.H., Bol, Martine E., Winkens, Bjorn, Essers, Brigitte, Weerwind, Patrick W., Maessen, Jos G., and van de Poll, Marcel C.G.
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- 2023
3. Epidemiology of patients presenting with dyspnea to emergency departments in Europe and the Asia-Pacific region
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Laribi, Said, Keijzers, Gerben, van Meer, Oene, Klim, Sharon, Motiejunaite, Justina, Kuan, Win Sen, Body, Richard, Jones, Peter, Karamercan, Mehmet, Craig, Simon, Harjola, Veli-Pekka, Holdgate, Anna, Golea, Adela, Graham, Colin, Verschuren, Franck, Capsec, Jean, Christ, Michael, Grammatico-Guillon, Leslie, Barletta, Cinzia, Garcia-Castrillo, Luis, and Kelly, Anne-Maree
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- 2018
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4. Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest
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Suverein, Martje M., primary, Delnoij, Thijs S.R., additional, Lorusso, Roberto, additional, Brandon Bravo Bruinsma, George J., additional, Otterspoor, Luuk, additional, Elzo Kraemer, Carlos V., additional, Vlaar, Alexander P.J., additional, van der Heijden, Joris J., additional, Scholten, Erik, additional, den Uil, Corstiaan, additional, Jansen, Tim, additional, van den Bogaard, Bas, additional, Kuijpers, Marijn, additional, Lam, Ka Yan, additional, Montero Cabezas, José M., additional, Driessen, Antoine H.G., additional, Rittersma, Saskia Z.H., additional, Heijnen, Bram G., additional, Dos Reis Miranda, Dinis, additional, Bleeker, Gabe, additional, de Metz, Jesse, additional, Hermanides, Renicus S., additional, Lopez Matta, Jorge, additional, Eberl, Susanne, additional, Donker, Dirk W., additional, van Thiel, Robert J., additional, Akin, Sakir, additional, van Meer, Oene, additional, Henriques, José, additional, Bokhoven, Karen C., additional, Mandigers, Loes, additional, Bunge, Jeroen J.H., additional, Bol, Martine E., additional, Winkens, Bjorn, additional, Essers, Brigitte, additional, Weerwind, Patrick W., additional, Maessen, Jos G., additional, and van de Poll, Marcel C.G., additional
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- 2023
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- View/download PDF
5. The emergency department arrival mode and its relations to ED management and 30-day mortality in acute heart failure: an ancillary analysis from the EURODEM study
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UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul-Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli-Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre-Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Schutte, Lot, de Kubber, Marije, Mignot-Evers, Lisette, Penninga-Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Geier, Felicitas, Smolarsky, Yvonne, Blaschke, Sabine, Kill, Clemens, Jerrentrup, Andreas, Hohenstein, Christian, Rockmann, Felix, Brünnler, Tanja, Ghuysen, Alexandre, Vranckx, Marc, Ergin, Mehmet, Dundar, Zerrin D., Altuncu, Yusuf A., Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Suurmunne, Hanna, Kokkonen, Liisa, Valli, Juha, Kiljunen, Minna, Kaye, Sanna, Mäkelä, Mikko, Metsäniitty, Juhani, Vaula, Eija, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul-Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli-Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre-Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Schutte, Lot, de Kubber, Marije, Mignot-Evers, Lisette, Penninga-Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Geier, Felicitas, Smolarsky, Yvonne, Blaschke, Sabine, Kill, Clemens, Jerrentrup, Andreas, Hohenstein, Christian, Rockmann, Felix, Brünnler, Tanja, Ghuysen, Alexandre, Vranckx, Marc, Ergin, Mehmet, Dundar, Zerrin D., Altuncu, Yusuf A., Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Suurmunne, Hanna, Kokkonen, Liisa, Valli, Juha, Kiljunen, Minna, Kaye, Sanna, Mäkelä, Mikko, Metsäniitty, Juhani, and Vaula, Eija
- Abstract
Background Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure patients’ ED management and short-term outcomes. Methods This was a sub-analysis of a European EURODEM study. Data on patients presenting with dyspnoea were collected prospectively from European EDs. Patients with ED diagnosis of acute heart failure were categorized into two groups: those using EMS and those self-presenting (non- EMS). The independent association between EMS use and 30-day mortality was evaluated with logistic regression. Results Of the 500 acute heart failure patients, with information about the arrival mode to the ED, 309 (61.8%) arrived by EMS. These patients were older (median age 80 vs. 75 years, p < 0.001), more often female (56.4% vs. 42.1%, p = 0.002) and had more dementia (18.7% vs. 7.2%, p < 0.001). On admission, EMS patients had more often confusion (14.2% vs. 2.1%, p < 0.001) and higher respiratory rate (24/min vs. 21/min, p = 0.014; respiratory rate > 30/min in 17.1% patients vs. 7.5%, p = 0.005). The only difference in ED management appeared in the use of ventilatory support: 78.3% of EMS patients vs. 67.5% of non- EMS patients received supplementary oxygen (p = 0.007), and non-invasive ventilation was administered to 12.5% of EMS patients vs. 4.2% non- EMS patients (p = 0.002). EMS patients were more often hospitalized (82.4% vs. 65.9%, p < 0.001), had higher in-hospital mortality (8.7% vs. 3.1%, p = 0.014) and 30-day mortality (14.3% vs. 4.9%, p < 0.001). The use of EMS was an independent predictor of 30-day mortality (OR = 2.54, 95% CI 1.11–5.81, p = 0.027). Conclusion Most acute heart failure patients arrive at ED by EMS. These patients suffer from more severe respiratory distress and receive more often ventilatory support. EMS use is an independent predictor of 30-day mortality.
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- 2022
6. The emergency department arrival mode and its relations to ED management and 30-day mortality in acute heart failure:an ancillary analysis from the EURODEM study
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Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrica, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Jansen, Joyce, Bouwhuis, Marna, Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrica, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Jansen, Joyce, and Bouwhuis, Marna
- Abstract
Background: Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure patients’ ED management and short-term outcomes. Methods: This was a sub-analysis of a European EURODEM study. Data on patients presenting with dyspnoea were collected prospectively from European EDs. Patients with ED diagnosis of acute heart failure were categorized into two groups: those using EMS and those self-presenting (non- EMS). The independent association between EMS use and 30-day mortality was evaluated with logistic regression. Results: Of the 500 acute heart failure patients, with information about the arrival mode to the ED, 309 (61.8%) arrived by EMS. These patients were older (median age 80 vs. 75 years, p < 0.001), more often female (56.4% vs. 42.1%, p = 0.002) and had more dementia (18.7% vs. 7.2%, p < 0.001). On admission, EMS patients had more often confusion (14.2% vs. 2.1%, p < 0.001) and higher respiratory rate (24/min vs. 21/min, p = 0.014; respiratory rate > 30/min in 17.1% patients vs. 7.5%, p = 0.005). The only difference in ED management appeared in the use of ventilatory support: 78.3% of EMS patients vs. 67.5% of non- EMS patients received supplementary oxygen (p = 0.007), and non-invasive ventilation was administered to 12.5% of EMS patients vs. 4.2% non- EMS patients (p = 0.002). EMS patients were more often hospitalized (82.4% vs. 65.9%, p < 0.001), had higher in-hospital mortality (8.7% vs. 3.1%, p = 0.014) and 30-day mortality (14.3% vs. 4.9%, p < 0.001). The use of EMS was an independent predictor of 30-day mortality (OR = 2.54, 95% CI 1.11–5.81, p = 0.027). Conclusion: Most acute heart failure patients arrive at ED by EMS. These patients suffer from more severe respiratory distress and receive more often ventilatory support. EMS use is an independent predictor of 30-day mortality.
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- 2022
7. Epidemiology, treatment and outcome of patients with lower respiratory tract infection presenting to emergency departments with dyspnoea (AANZDEM and EuroDEM studies).
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UCL - (SLuc) Service des urgences, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, Rousseau, Geoffroy, Keijzers, Gerben, van Meer, Oene, Craig, Simon, Karamercan, Mehmet, Klim, Sharon, Body, Richard, Kuan, Win Sen, Harjola, Veli-Pekka, Jones, Peter, Verschuren, Franck, Holdgate, Anna, Christ, Michael, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Graham, Colin A, Garcia-Castrillo, Luis, Laribi, Said, Kelly, Anne-Maree, UCL - (SLuc) Service des urgences, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, Rousseau, Geoffroy, Keijzers, Gerben, van Meer, Oene, Craig, Simon, Karamercan, Mehmet, Klim, Sharon, Body, Richard, Kuan, Win Sen, Harjola, Veli-Pekka, Jones, Peter, Verschuren, Franck, Holdgate, Anna, Christ, Michael, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Graham, Colin A, Garcia-Castrillo, Luis, Laribi, Said, and Kelly, Anne-Maree
- Abstract
Lower respiratory tract infection (LRTI) is a frequent cause of dyspnoea in EDs, and is associated with considerable morbidity and mortality. We described and compared the management of this disease in Europe and Oceania/South-East Asia (SEA) cohorts. We conducted a prospective cohort study with three time points in Europe and Oceania/SEA. We included in this manuscript patients presenting to EDs with dyspnoea and a diagnosis of LRTI in ED. We collected comorbidities, chronic medication, clinical signs at arrival, laboratory parameters, ED management and patient outcomes. A total of 1389 patients were included, 773 in Europe and 616 in SEA. The European cohort had more comorbidities including chronic heart failure, obesity, chronic obstructive pulmonary disease and smoking. Levels of inflammatory markers were higher in Europe. There were more patients with inflammatory markers in Europe and more hypercapnia in Oceania/SEA. The use of antibiotics was higher in SEA (72.2% vs 61.8%, P < 0.001) whereas intravenous diuretics, non-invasive and invasive ventilation were higher in Europe. Intensive care unit admission rate was 9.9% in Europe cohort and 3.4% in Oceania/SEA cohort. ED mortality was 1% and overall in-hospital mortality was 8.7% with no differences between regions. More patients with LRTI in Europe presented with cardio-respiratory comorbidities, they received more adjunct therapies and had a higher intensive care unit admission rate than patients from Oceania/SEA, although mortality was similar between the two cohorts.
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- 2021
8. Seasonal variations of patients presenting dyspnea to emergency departments in Europe:Results from the EURODEM Study
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Rangé, Gregoire, Saint Etienne, Christophe, Marcollet, Pierre, Chassaing, Stephan, Dequenne, Philippe, Hakim, Radwan, Capsec, Jean, Laure, Christophe, Gautier, Sandra, Albert, Franck, Godillon, Lucile, Stolt, Pelle, Motreff, Pascal, Grammatico-Guillon, Leslie, Karamercan, Mehmet Akif, Dündar, Zerrin Defne, van Meer, Oene, Body, Richard, Harjola, Veli-Pekka, Verschuren, Franck, Christ, Michael, Golea, Adela, Barletta, Cinzia, Garcia-Castrillo, Luis, Altunci, Yusuf Ali, Katirci, Yavuz, Kelly, Anne-Maree, Laribi, Said, Hôpital Louis Pasteur [Chartres], CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre Hospitalier Jacques Coeur, Clinique Saint Gatien, Hôpitaux de Chartres [Chartres], Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), Maglia Rotta, Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Unité d'Épidémiologie des données cliniques [Tours] (EpiDcliC), Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Emergency Department (FV - ED), Saint Luc University Hospital, HUS Emergency Medicine and Services, University of Helsinki, and Faculty of Medicine
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Male ,Ambulances ,Comorbidity ,030204 cardiovascular system & hematology ,[SHS]Humanities and Social Sciences ,Cohort Studies ,0302 clinical medicine ,Epidemiology ,Risk-Factors ,Prospective Studies ,Diuretics ,Prospective cohort study ,ComputingMilieux_MISCELLANEOUS ,Aged, 80 and over ,0303 health sciences ,COPD ,education.field_of_study ,Age Factors ,General Medicine ,Middle Aged ,humanities ,ED diagnosis ,Anti-Bacterial Agents ,Bronchodilator Agents ,3. Good health ,Europe ,Hospitalization ,Female ,Seasons ,Emergency Service, Hospital ,medicine.medical_specialty ,emergency department ,Population ,Outcomes ,Article ,Exacerbations ,03 medical and health sciences ,older patient ,Lower respiratory tract infection ,medicine ,Humans ,education ,Aged ,030306 microbiology ,business.industry ,seasonal variations ,Oxygen Inhalation Therapy ,Emergency department ,Pneumonia ,3126 Surgery, anesthesiology, intensive care, radiology ,medicine.disease ,Dyspnea ,Emergency medicine ,Copd ,business - Abstract
Background/aim: To describe seasonal variations in epidemiology, management, and short-term outcomes of patients in Europe presenting to an emergency department (ED) with a main complaint of dyspnea. Materials and methods: An observational prospective cohort study was performed in 66 European EDs which included consecutive patients presenting to EDs with dyspnea as the main complaint during 3 72-h study periods. Data were collected on demographics, comorbidities, chronic treatment, prehospital treatment, mode of arrival of patient to ED, clinical signs at admission, treatment in the ED, ED diagnosis, discharge from ED, and in-hospital outcome. Results: The study included 2524 patients with a median age of 69 (53–80) years old. Of the patients presented, 991 (39.3%) were in autumn, 849 (33.6%) were in spring, and 48 (27.1%) were in winter. The winter population was significantly older (P < 0.001) and had a lower rate of ambulance arrival to ED (P < 0.001). In the winter period, there was a higher rate for lower respiratory tract infection (35.1%), and patients were more hypertensive, more hypoxic, and more hyper/hypothermic compared to other seasons. The ED mortality was about 1% and, in hospital, mortality for admitted patients was 7.4%. Conclusion: The analytic method and the outcome of this study may help to guide the allocation of ED resources more efficiently and to recommend seasonal ED management protocols based on the seasonal trend of dyspneic patients. © TÜBİTAK., Lietuvos Mokslo Taryba: MIP-049/2015, We would like to thank Toine van den Ende and Ans Kluivers for their assistance in collecting data in Europe. The work of Justina Motiejunaite was supported by the Research Council of Lithuania (Grant No. MIP-049/2015), as well as by training grants from the French government, the Embassy of France in Lithuania, and the Erasmus Program. The EuroDEM study protocol and informed consent was received and reviewed by the institutional review board and ethical committee for each country (and/ or institution), and all participants provided informed consent. The EuroDEM study was done under the supervision of the EUSEM Research Committee. Data management in Europe was facilitated by the Jeroen Bosch Hospital., The work of Justina Motiejunaite was supported by the Research Council of Lithuania (Grant No. MIP-049/2015), as well as by training grants from the French government, the Embassy of France in Lithuania, and the Erasmus Program.
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- 2020
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9. Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub-optimal
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Van Meer, Oene, Keijzers, Gerben, Motiejunaite, Justina, Klim, Sharon, Capsec, Jean, Kuan, Win, McNulty, Richard, Tan, Clifford, Cowell, David Lord, Holdgate, Anna, Jain, Nitin, Devillecourt, Tracey, Forrester, Alan, Lee, Kendall, Chalkley, Dane, Gillett, Mark, Lozzi, Lydia, Asha, Stephen, Duffy, Martin, Watkins, Gina, Stone, Richard, Rosengren, David, Thone, Jae, Martin, Shane, Orda, Ulrich, Thom, Ogilvie, Kinnear, Frances, Eley, Rob, Ryan, Alison, Morel, Douglas, May, Christopher, Furyk, Jeremy, Thomson, Graeme, Smith, Simon, Smith, Richard, Maclean, Andrew, Grummisch, Michelle, Meyer, Alistair, Meek, Robert, Rosengarten, Pamela, Chan, Barry, Haythorne, Helen, Archer, Peter, Craig, Simon, Wilson, Kathryn, Knott, Jonathan, Ritchie, Peter, Bryant, Michael, MacDonald, Stephen, Lee, Tom, Mahlangu, Mlungisi, Mountain, David, Rogers, Ian, Otto, Tobias, Stuart, Peter, Bament, Jason, Brown, Michelle, Jones, Peter, Greven‐Garcia, Renee, Scott, Michael, Cheri, Thomas, Nguyen, Mai, Graham, Colin, Wong, Chi‐Pang, Wong, Tai Wai, Leung, Ling‐Pong, Man, Chan Ka, Saiboon, Ismail Mohd, Rahman, Nik Hisamuddin, Lee, Wee Yee, Lee, Francis Chun Yue, Kuan, Win Sen, Russell, SharonKerrie, Kelly, Anne‐Maree, Laribi, Gerbenand Said, Lawoko, Charles, Laribi, Said, Meer, Oene, Harjola, Veli‐Pekka, Golea, Adela, Christ, Michael, Garcia‐Castrillo, Luis, Al Dandachi, Ghanima, Maignan, Maxime, Hermand, DominiqueChristelle, Tessier, Cindy, Roy, Pierre‐Marie, Bucco, Lucie, Barletta, Cinzia, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Mackaij‐Staal, Charlotte, Schutte, Lot, Kubber, Marije, Mignot‐Evers, Lisette, Penninga‐Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Body, Richard, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Smolarsky, Yvonne, Blaschke, Sabine, Jerrentrup, ClemensAndreas, Hohenstein, Christian, Brünnler, FelixTanja, Ghuysen, Alexandre, Vranckx, Marc, Verschuren, Franck, Karamercan, Mehmet, Ergin, Mehmet, Dundar, Zerrin, Altuncu, Yusuf, Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Kokkonen, Liisa, Valli, JukkaJuha, Kiljunen, Minna, Tolonen, Jukka, Kaye, Sanna, Mäkelä, JukkaMikko, Metsäniitty, JukkaJuhani, Vaula, Eija, Duytsche, Nicolas, Garmilla, Pablo, HUS Emergency Medicine and Services, Department of Diagnostics and Therapeutics, University of Helsinki, Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Indian Institute of Technology Kharagpur (IIT Kharagpur), University of Leicester, Smith Watkins Trumpets, Institute for Fiscal Studies, Leibniz Institute for Tropospheric Research (TROPOS), University of California [Santa Barbara] (UCSB), University of California, iThemba Laboratory for Accelerator Based Science, Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Hospitalier Universitaire [Grenoble] (CHU), Emergency Department (FV - ED), and Saint Luc University Hospital
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Male ,medicine.medical_specialty ,emergency department ,[SDV]Life Sciences [q-bio] ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,ACUTE EXACERBATIONS ,Pulmonary Disease, Chronic Obstructive ,03 medical and health sciences ,0302 clinical medicine ,Dyspnoea ,Internal Medicine ,medicine ,COPD ,Humans ,Prospective Studies ,030212 general & internal medicine ,PREDICTORS ,Prospective cohort study ,Emergency Treatment ,ComputingMilieux_MISCELLANEOUS ,Aged ,Aged, 80 and over ,Mechanical ventilation ,ASIA ,Australasia ,business.industry ,NEW-ZEALAND DYSPNEA ,Emergency department ,Guideline ,Middle Aged ,medicine.disease ,3. Good health ,Europe ,Respiratory acidosis ,3121 General medicine, internal medicine and other clinical medicine ,Practice Guidelines as Topic ,Emergency medicine ,outcome ,Breathing ,Female ,Observational study ,Emergency Service, Hospital ,business ,management - Abstract
OBJECTIVES: Exacerbations of chronic obstructive pulmonary disease (COPD) are common in emergency departments (ED). Guidelines recommend administration of inhaled bronchodilators, systemic corticosteroids and antibiotics along with non-invasive ventilation (NIV) for patients with respiratory acidosis. We aimed to determine compliance with guideline recommendations for patients with treated for COPD in ED in Europe (EUR) and South East Asia/Australasia (SEA) and to compare management and outcomes. METHODS: In each region, an observational prospective cohort study was performed that included patients presenting to EDs with the main complaint of dyspnoea during three 72-hour periods. This planned sub-study included those with an ED primary discharge diagnosis of COPD. Data were collected on demographics, clinical features, treatment, disposition and in-hospital mortality. We determined overall compliance with guideline recommendations and compared treatments and outcome between regions. RESULTS: 801 patients were included from 122 EDs (66 EUR and 46 SEA). Inhaled bronchodilators were administered to 80.3% of patients, systemic corticosteroids to 59.5%, antibiotics to 44% and 60.6% of patients with pH
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- 2020
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10. Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub-optimal
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Kelly, AM, van Meer, Oene, Keijzers, Gerben, Motiejunaite, Justina, Jones, Peter, Body, Richard, Craig, Simon, Karamercan, Mehmet, Klim, Sharon, Harjola, Veli-Pekka, Laribi, Said, and Emergency Medicine
- Abstract
Background Exacerbations of chronic obstructive pulmonary disease (COPD) are common in emergency departments (ED). Guidelines recommend administration of inhaled bronchodilators, systemic corticosteroids and antibiotics along with non-invasive ventilation (NIV) for patients with respiratory acidosis. Aim To determine compliance with guideline recommendations for patients treated for COPD in ED in Europe (EUR) and South East Asia/Australasia (SEA) and to compare management and outcomes. Methods In each region, an observational prospective cohort study was performed that included patients presenting to ED with the main complaint of dyspnoea during three 72-h periods. This planned sub-study included those with an ED primary discharge diagnosis of COPD. Data were collected on demographics, clinical features, treatment, disposition and in-hospital mortality. We determined overall compliance with guideline recommendations and compared treatments and outcome between regions. Results A total of 801 patients was included from 122 ED (66 EUR and 46 SEA). Inhaled bronchodilators were administered to 80.3% of patients, systemic corticosteroids to 59.5%, antibiotics to 44 and 60.6% of patients with pH Conclusion Compliance with guideline recommended treatments, in particular administration of corticosteroids and NIV, was sub-optimal in both regions. Improved compliance has the potential to improve patient outcome.
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- 2020
11. Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub-optimal.
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UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Kelly, Anne-Maree, Van Meer, Oene, Keijzers, Gerben, Motiejunaite, Justina, Jones, Peter, Body, Richard, Craig, Simon, Karamercan, Mehmet, Klim, Sharon, Harjola, Veli-Pekka, Verschuren, Franck, Holdgate, Anna, Christ, Michael, Golea, Adela, Graham, Colin A, Capsec, Jean, Barletta, Cinzia, Garcia-Castrillo, Luis, Kuan, Win S, Laribi, Said, AANZDEM and EuroDEM Study Groups, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Kelly, Anne-Maree, Van Meer, Oene, Keijzers, Gerben, Motiejunaite, Justina, Jones, Peter, Body, Richard, Craig, Simon, Karamercan, Mehmet, Klim, Sharon, Harjola, Veli-Pekka, Verschuren, Franck, Holdgate, Anna, Christ, Michael, Golea, Adela, Graham, Colin A, Capsec, Jean, Barletta, Cinzia, Garcia-Castrillo, Luis, Kuan, Win S, Laribi, Said, and AANZDEM and EuroDEM Study Groups
- Abstract
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are common in emergency departments (ED). Guidelines recommend administration of inhaled bronchodilators, systemic corticosteroids and antibiotics along with non-invasive ventilation (NIV) for patients with respiratory acidosis. AIM: To determine compliance with guideline recommendations for patients treated for COPD in ED in Europe (EUR) and South East Asia/Australasia (SEA) and to compare management and outcomes. METHODS: In each region, an observational prospective cohort study was performed that included patients presenting to ED with the main complaint of dyspnoea during three 72-h periods. This planned sub-study included those with an ED primary discharge diagnosis of COPD. Data were collected on demographics, clinical features, treatment, disposition and in-hospital mortality. We determined overall compliance with guideline recommendations and compared treatments and outcome between regions. RESULTS: A total of 801 patients was included from 122 ED (66 EUR and 46 SEA). Inhaled bronchodilators were administered to 80.3% of patients, systemic corticosteroids to 59.5%, antibiotics to 44 and 60.6% of patients with pH <7.3 received NIV. The proportion administered systemic corticosteroids was higher in SEA (EUR vs SEA for all comparisons; 52 vs 66%, P < 0.001) as was administration of antibiotics (40 vs 49%, P = 0.02). Rates of NIV and mechanical ventilation were similar. Overall in-hospital mortality was 4.2% (SEA 3.9% vs EUR 4.5%, P = 0.77). CONCLUSION: Compliance with guideline recommended treatments, in particular administration of corticosteroids and NIV, was sub-optimal in both regions. Improved compliance has the potential to improve patient outcome.
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- 2020
12. Seasonal variations of patients presenting dyspnea to emergency departments in Europe: Results from the EURODEM Study
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UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Karamercan, Mehmet Akif, Dündar, Zerrin Defne, Ergin, Mehmet, VAN Meer, Oene, Body, Richard, Harjola, Veli-Pekka, Verschuren, Franck, Christ, Micheal, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Garcia-Castrillo, Luis, Altuncı, Yusuf Ali, Katırcı, Yavuz, Kelly, Anne-Maree, Laribi, Said, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Karamercan, Mehmet Akif, Dündar, Zerrin Defne, Ergin, Mehmet, VAN Meer, Oene, Body, Richard, Harjola, Veli-Pekka, Verschuren, Franck, Christ, Micheal, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Garcia-Castrillo, Luis, Altuncı, Yusuf Ali, Katırcı, Yavuz, Kelly, Anne-Maree, and Laribi, Said
- Abstract
BACKGROUND/AIM: To describe seasonal variations in epidemiology, management, and short-term outcomes of patients in Europe presenting to an emergency department (ED) with a main complaint of dyspnea. MATERIALS AND METHODS: Anobservational prospective cohort study was performed in 66 European EDs which included consecutive patients presenting to EDs with dyspnea as the main complaint during 3 72-h study periods. Data were collected on demographics, comorbidities, chronic treatment, prehospital treatment, mode of arrival of patient to ED, clinical signs at admission, treatment in the ED, ED diagnosis, discharge from ED, and in-hospital outcome. RESULTS: The study included 2524 patients with a median age of 69 (53–80) years old. Of the patients presented, 991 (39.3%) were in autumn, 849 (33.6%) were in spring, and 48 (27.1%) were in winter. The winter population was significantly older (P < 0.001) and had a lower rate of ambulance arrival to ED (P < 0.001). In the winter period, there was a higher rate for lower respiratory tract infection (35.1%), and patients were more hypertensive, more hypoxic, and more hyper/hypothermic compared to other seasons. The ED mortality was about 1% and, in hospital, mortality for admitted patients was 7.4%. CONCLUSION: The analytic method and the outcome of this study may help to guide the allocation of ED resources more efficiently and to recommend seasonal ED management protocols based on the seasonal trend of dyspneic patients.
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- 2020
13. Seasonal variations of patients presenting dyspnea to emergency departments in Europe: Results from the EURODEM Study
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KARAMERCAN, Mehmet Akif, primary, DÜNDAR, Zerrin Defne, additional, ERGİN, Mehmet, additional, VAN MEER, Oene, additional, BODY, Richard, additional, HARJOLA, Veli-Pekka, additional, VERSCHUREN, Franck, additional, CHRIST, Michael, additional, GOLEA, Adela, additional, CAPSEC, Jean, additional, BARLETTA, Cinzia, additional, GARCIA-CASTRILLO, Luis, additional, ALTUNCI, Yusuf Ali, additional, KATIRCI, Yavuz, additional, KELLY, Anne-Maree, additional, and LARIBI, Said, additional
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- 2020
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14. Epidemiology, treatment and outcome of patients with lower respiratory tract infection presenting to emergency departments with dyspnoea ( AANZDEM and EuroDEM studies)
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Rousseau, Geoffroy, primary, Keijzers, Gerben, additional, van Meer, Oene, additional, Craig, Simon, additional, Karamercan, Mehmet, additional, Klim, Sharon, additional, Body, Richard, additional, Kuan, Win Sen, additional, Harjola, Veli‐Pekka, additional, Jones, Peter, additional, Verschuren, Franck, additional, Holdgate, Anna, additional, Christ, Michael, additional, Golea, Adela, additional, Capsec, Jean, additional, Barletta, Cinzia, additional, Graham, Colin A, additional, Garcia‐Castrillo, Luis, additional, Laribi, Said, additional, and Kelly, Anne‐Maree, additional
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- 2020
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15. Epidemiology of patients presenting with dyspnea to emergency departments in Europe and the Asia-Pacific region
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Laribi, Said, primary, Keijzers, Gerben, additional, van Meer, Oene, additional, Klim, Sharon, additional, Motiejunaite, Justina, additional, Kuan, Win Sen, additional, Body, Richard, additional, Jones, Peter, additional, Karamercan, Mehmet, additional, Craig, Simon, additional, Harjola, Veli-Pekka, additional, Holdgate, Anna, additional, Golea, Adela, additional, Graham, Colin, additional, Verschuren, Franck, additional, Capsec, Jean, additional, Christ, Michael, additional, Grammatico-Guillon, Leslie, additional, Barletta, Cinzia, additional, Garcia-Castrillo, Luis, additional, and Kelly, Anne-Maree, additional
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- 2019
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16. Treatment and outcome of adult patients with acute asthma in emergency departments in Australasia, South East Asia and Europe: Are guidelines followed? AANZDEM/EuroDEM study
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Craig, Simon, primary, Kuan, Win Sen, additional, Kelly, Anne‐Maree, additional, Van Meer, Oene, additional, Motiejunaite, Justina, additional, Keijzers, Gerben, additional, Jones, Peter, additional, Body, Richard, additional, Karamercan, Mehmet A, additional, Klim, Sharon, additional, Harjola, Veli‐Pekka, additional, Verschuren, Franck, additional, Holdgate, Anna, additional, Christ, Michael, additional, Golea, Adela, additional, Graham, Colin A, additional, Capsec, Jean, additional, Barletta, Cinzia, additional, Garcia‐Castrillo, Luis, additional, and Laribi, Said, additional
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- 2019
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17. Epidemiology, treatment and outcome of patients with lower respiratory tract infection presenting to emergency departments with dyspnoea (AANZDEM and EuroDEM studies).
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Rousseau, Geoffroy, Keijzers, Gerben, van Meer, Oene, Craig, Simon, Karamercan, Mehmet, Klim, Sharon, Body, Richard, Kuan, Win Sen, Harjola, Veli‐Pekka, Jones, Peter, Verschuren, Franck, Holdgate, Anna, Christ, Michael, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Graham, Colin A, Garcia‐Castrillo, Luis, Laribi, Said, and Kelly, Anne‐Maree
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DYSPNEA ,HOSPITAL emergency services ,LONGITUDINAL method ,EVALUATION of medical care ,RESPIRATORY infections ,COMORBIDITY ,DESCRIPTIVE statistics - Abstract
Objective: Lower respiratory tract infection (LRTI) is a frequent cause of dyspnoea in EDs, and is associated with considerable morbidity and mortality. We described and compared the management of this disease in Europe and Oceania/South‐East Asia (SEA) cohorts. Methods: We conducted a prospective cohort study with three time points in Europe and Oceania/SEA. We included in this manuscript patients presenting to EDs with dyspnoea and a diagnosis of LRTI in ED. We collected comorbidities, chronic medication, clinical signs at arrival, laboratory parameters, ED management and patient outcomes. Results: A total of 1389 patients were included, 773 in Europe and 616 in SEA. The European cohort had more comorbidities including chronic heart failure, obesity, chronic obstructive pulmonary disease and smoking. Levels of inflammatory markers were higher in Europe. There were more patients with inflammatory markers in Europe and more hypercapnia in Oceania/SEA. The use of antibiotics was higher in SEA (72.2% vs 61.8%, P < 0.001) whereas intravenous diuretics, non‐invasive and invasive ventilation were higher in Europe. Intensive care unit admission rate was 9.9% in Europe cohort and 3.4% in Oceania/SEA cohort. ED mortality was 1% and overall in‐hospital mortality was 8.7% with no differences between regions. Conclusions: More patients with LRTI in Europe presented with cardio‐respiratory comorbidities, they received more adjunct therapies and had a higher intensive care unit admission rate than patients from Oceania/SEA, although mortality was similar between the two cohorts. [ABSTRACT FROM AUTHOR]
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- 2021
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18. Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub-optimal.
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Kelly AM, Van Meer O, Keijzers G, Motiejunaite J, Jones P, Body R, Craig S, Karamercan M, Klim S, Harjola VP, Verschuren F, Holdgate A, Christ M, Golea A, Graham CA, Capsec J, Barletta C, Garcia-Castrillo L, Kuan WS, and Laribi S
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- Aged, Aged, 80 and over, Australasia, Emergency Service, Hospital, Europe, Female, Humans, Male, Middle Aged, Prospective Studies, Pulmonary Disease, Chronic Obstructive diagnosis, Emergency Treatment, Practice Guidelines as Topic, Pulmonary Disease, Chronic Obstructive therapy
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- 2020
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19. [Dyspnea and globus sensation after a minor head injury].
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Aukema A, van Meer OA, and Locher H
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- Aged, 80 and over, Conservative Treatment, Craniocerebral Trauma diagnostic imaging, Craniocerebral Trauma physiopathology, Dyspnea, Female, Globus Sensation diagnostic imaging, Globus Sensation physiopathology, Humans, Tomography, X-Ray Computed, Craniocerebral Trauma complications, Globus Sensation etiology, Hematoma diagnostic imaging, Pharyngeal Diseases diagnostic imaging, Spine diagnostic imaging
- Abstract
A 91-year-old woman visited the emergency department with dyspnea and globus sensation after a minor head injury. A CT-scan of the spine showed a retropharyngeal swelling. MRI and fiberscopy revealed that the swelling was concordant with a retropharyngeal hematoma. The patient was admitted for observation and she was discharged in good clinical condition the day after.
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- 2019
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