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5. Position paper on olfactory dysfunction: 2023

Author

Whitcroft, K L, primary, Altundag, A, additional, Balungwe, P, additional, Boscolo-Rizzo, P, additional, Douglas, R, additional, Enecilla, M L B, additional, Fjaeldstad, A W, additional, Fornazieri, M A, additional, Frasnelli, J, additional, Gane, S, additional, Gudziol, H, additional, Gupta, N, additional, Haehner, A, additional, Hernandez, A K, additional, Holbrook, E H, additional, Hopkins, C, additional, Hsieh, J W, additional, Huart, C, additional, Husain, S, additional, Kamel, R, additional, Kim, J K, additional, Kobayashi, M, additional, Konstantinidis, I, additional, Landis, B N, additional, Lechner, M, additional, Macchi, A, additional, Mazal, P P, additional, Miri, I, additional, Miwa, T, additional, Mori, E, additional, Mullol, J, additional, Mueller, C A, additional, Ottaviano, G, additional, Patel, Z M, additional, Philpott, C, additional, Pinto, J M, additional, Ramakrishnan, V R, additional, Roth, Y, additional, Schlosser, R J, additional, Stjärne, P, additional, Van Gerven, L, additional, Vodicka, J, additional, Welge-Luessen, A, additional, Wormald, P J, additional, and Hummel, T, additional

Published
2023
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6. Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium: a BelSACI-Abeforcal-EUFOREA statement

Author

Hellings, P. W., Pugin, B., Mariën, G., Bachert, C., Breynaert, C., Bullens, D. M., Ceuppens, J. L., Clement, G., Cox, T., Ebo, D., Gevaert, P., Halewyck, S., Hox, V., Ladha, K., Jacobs, R., Rombaux, P., Schrijvers, R., Speleman, K., Van der Brempt, X., Van Gerven, L., Vanderveken, O., Verhaeghe, B., Vierstraete, K., Vlaminck, S., Watelet, J. -B., Bousquet, J., and Seys, S. F.

Published
2019
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7. Depression, loneliness and apathy in older breast cancer survivors: five-year follow-up from the Climb Every Mountain study

Author

Lemij, A., primary, De Glas, N.A., additional, van Dalen, T., additional, Guicherit, O.R., additional, Lans, T.E., additional, Linthorst-Niers, E.M.H., additional, Merkus, J.W.S., additional, van der Pol, C.C., additional, Vulink, A.J.E., additional, van Gerven, L., additional, Liefers, G.J., additional, and Portielje, J.E.A., additional

Published
2022
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9. Physical function in older patients with breast cancer: five-year follow-up from the CLIMB study

Author

Lemij, A., primary, de Glas, N., additional, Derks, M., additional, Bastiaannet, E., additional, Merkus, J., additional, Lans, T., additional, van der Pol, C., additional, van Dalen, T., additional, Vulink, A., additional, van Gerven, L., additional, Guicherit, O., additional, Linthorst-Niers, E., additional, Liefers, G.J., additional, and Portielje, J., additional

Published
2022
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10. 171P Association of breast cancer therapy with cognitive decline in older women with early breast cancer: Findings from the CLIMB study

Author

Baltussen, J., primary, Derks, M.G.M., additional, Lemij, A.A., additional, de Glas, N.A., additional, Fiocco, M., additional, Linthorst-Niers, E., additional, Vulink, A., additional, Van Gerven, L., additional, Guicherit, O.R., additional, Van Dalen, T., additional, Merkus, J.W.S., additional, Lans, T., additional, Van der Pol, C.C., additional, Mooijaart, S.P., additional, Portielje, J.E.A., additional, and Liefers, G.J., additional

Published
2022
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14. Non‐allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology

Author

Hellings, P. W., Klimek, L., Cingi, C., Agache, I., Akdis, C., Bachert, C., Bousquet, J., Demoly, P., Gevaert, P., Hox, V., Hupin, C., Kalogjera, L., Manole, F., Mösges, R., Mullol, J., Muluk, N. B., Muraro, A., Papadopoulos, N., Pawankar, R., Rondon, C., Rundenko, M., Seys, S. F., Toskala, E., Van Gerven, L., Zhang, L., Zhang, N., and Fokkens, W. J.

Published
2017
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15. Predicting postoperative complications and their impact on quality of life and functional status in older patients with breast cancer

Author

Lemij, A A, primary, van der Plas-Krijgsman, W G, additional, Bastiaannet, E, additional, Merkus, J W S, additional, van Dalen, T, additional, Vulink, A J E, additional, van Gerven, L, additional, Guicherit, O R, additional, Linthorst-Niers, E M H, additional, Lans, T E, additional, van der Pol, C C, additional, Wyld, L, additional, Morgan, J L, additional, Portielje, J E A, additional, de Glas, N A, additional, and Liefers, G J, additional

Published
2022
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16. Epithelial and sensory mechanisms of nasal hyperreactivity

Author

Velasco E, Delicado-Miralles M, Hellings P, Gallar J, Van Gerven L, and Talavera K

Subjects
sensory nerve, nasal mucosa, mucus secretion, TRP channel, barrier function
Abstract

"Nasal hyperreactivity" is a key feature in various phenotypes of upper airway diseases, whereby reactions of the nasal epithelium to diverse chemical and physical stimuli are exacerbated. In this review, we illustrate how nasal hyperreactivity can result from at least three types of mechanisms: (1) impaired barrier function, (2) hypersensitivity to external and endogenous stimuli, and (3) potentiation of efferent systems. We describe the known molecular basis of hyperreactivity related to the functional impairment of epithelial cells and somatosensory innervation, and indicate that the thermal, chemical, and mechanical sensors determining hyperreactivity in humans remain to be identified. We delineate research directions that may provide new insights into nasal hyperreactivity associated with rhinitis/rhinosinusitis pathophysiology and therapeutics. The elucidation of the molecular mechanisms underlying nasal hyperreactivity is essential for the treatment of rhinitis according to the precepts of precision medicine.

Published
2022

17. Additional file 2 of Positive health during the COVID-19 pandemic: a survey among community-dwelling older individuals in the Netherlands

Author

Moens, I. S., van Gerven, L. J., Debeij, S. M., Bakker, C. H., Moester, M. J. C., Mooijaart, S. P., van der Pas, S., Vangeel, M., Gussekloo, J., Drewes, Y. M., and Elzen, W. P. J.den

Subjects
sense organs
Abstract

Additional file 2. Self-rated change in the six dimensions of Positive Health compared to the year before the COVID-19 pandemic in older individuals living in the Netherlands (n=834).

Published
2022
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18. PCLake manual

Author

Janssen, A.B.G., Kuiper, J.J., Janse, J.H., van Gerven, L., de Klein, J.J.M., Kramer, L., Mooij, W.M., and Teurlincx, S.

Subjects
Aquatic Ecology and Water Quality Management, WIMEK, PCLake, PCLake+, PCModel, Life Science, Water Systems and Global Change, Aquatische Ecologie en Waterkwaliteitsbeheer, PE&RC, manual
Abstract

The user manual of PCLake. This document contains exercises and examples for the application of PCLake., Corrected typographical errors.

Published
2022

19. Additional file 3 of Positive health during the COVID-19 pandemic: a survey among community-dwelling older individuals in the Netherlands

Author

Moens, I. S., van Gerven, L. J., Debeij, S. M., Bakker, C. H., Moester, M. J. C., Mooijaart, S. P., van der Pas, S., Vangeel, M., Gussekloo, J., Drewes, Y. M., and Elzen, W. P. J.den

Abstract

Additional file 3. Self-rated change (%), compared to before the COVID-19 pandemic, in the six dimensions of Positive Health of older individuals living in the Netherlands depending on sex, age, living situation and self-rated general health (n=834). * = statistically significant.

Published
2022
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21. Differences in treatment and survival of older patients with operable breast cancer between the United Kingdom and the Netherlands – a comparison of two national prospective longitudinal multi-centre cohort studies

Author

van der Plas-Krijgsman, W., primary, Morgan, J., additional, de Glas, N., additional, de Boer, A., additional, Martin, C., additional, Holmes, G., additional, Ward, S., additional, Chater, T., additional, Reed, M., additional, Merkus, J., additional, van Dalen, T., additional, Vulink, A., additional, van Gerven, L., additional, Guicherit, O., additional, Linthorst, E., additional, Bastiaannet, E., additional, Portielje, J., additional, Liefers, G.J., additional, and Wyld, L., additional

Published
2021
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22. Discontinuation of adjuvant endocrine therapy and impact on quality of life and functional status in older patients with breast cancer

Author

Lemij, A., primary, de Glas, N., additional, Derks, M., additional, Bastiaannet, E., additional, Merkus, J., additional, Lans, T., additional, van der Pol, C., additional, van Dalen, T., additional, Vulink, A., additional, van Gerven, L., additional, Guicherit, O., additional, Linthorst-Niers, E., additional, Liefers, G.J., additional, and Portielje, J., additional

Published
2021
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23. Personal protection and delivery of rhinologic and endoscopic skull base procedures during the COVID-19 outbreak: ERS endorsed advises

Author

Van Gerven, L., Hellings, P. W., Cox, T., Fokkens, W., Hopkins, C., Hox, V, Jorissen, M., Schuermans, A., Sinonquel, P., Speleman, K., Vander Poorten, V., Van Gool, K., Van Zele, T., Alobid, I, Ear, Nose and Throat, AII - Inflammatory diseases, COX, Tony, Vander Poorten, V, Alobid, I, Van Gerven, L, Van Gool, K, Schuermans, A, Van Zele, T, Jorissen, M, Hopkins, C, Hox, V, Speleman, K, Sinonquel, P, Hellings, PW, and Fokkens, W

Subjects
SARS-CoV-2, Infection prevention, Personal protective equipment, COVID-19, Skull base surgery, Human medicine, Rhinology, Endoscopic surgery
Abstract

On March 11th 2020, the World Health Organization (WHO) declared COVID-19 pandemic, with subsequent profound impact on the entire health care system. During the COVID-19 outbreak, activities in the rhinology outpatient clinic and operation rooms are limited to emergency care only. Health care practitioners are faced with the need to perform rhinological and skull base emergency procedures in patients with a positive or unknown COVID-19 status. This article aims to provide recommendations and relevant information for rhinologists, based on the limited amount of (anecdotal) data, to guarantee high-quality patient care and adequate levels of infection prevention in the rhinology clinic.

Published
2020

25. EPOS 4 Patients.

Author

UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hopkins, C, Surda, P, Walker, A, Wolf, A, Speth, M M, Jacques, T, Hox, V, Van Gerven, L, Santamaria-Gadea, A, Segboer, C, Lourijsen, E, Turri-Zanoni, M, Huart, C, Rennie, C, Green, R, The Samter's Society, The Samter's Society, Kelly, C E, Knill, A, Lund, V J, Fokkens, W J, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hopkins, C, Surda, P, Walker, A, Wolf, A, Speth, M M, Jacques, T, Hox, V, Van Gerven, L, Santamaria-Gadea, A, Segboer, C, Lourijsen, E, Turri-Zanoni, M, Huart, C, Rennie, C, Green, R, The Samter's Society, The Samter's Society, Kelly, C E, Knill, A, Lund, V J, and Fokkens, W J

Abstract

EPOS2020 is the 4th and most recent version of the European Position Paper on Rhinosinusitis and Nasal Polyps which was first published in 2005. It aims to provide the most up to date scientifically robust information on the topic published in the literature which has been critically analysed by an international group of clinicians drawn from all disciplines dealing with these problems together with patients. The guidelines offer evidence-based recommendations and care pathways for acute and chronic rhinosinusitis in both adults and children. Management of these diseases from the patients' perspective is an important part of EPOS2020. Not only is this included in the main document but, for the first time, we have produced a separate supplement dedicated to and in collaboration with patients, EPOS4Patients, which aims to provide information in an accessible format, to answer frequently asked questions about these diseases and their treatment options as well as including useful patient resources and websites. It has never been more important for patients to be actively involved in their care. Being well informed helps you to make the best decisions together with your doctor.

Published
2021

26. EPOS 4 Patients.

Author

UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hopkins, C, Surda, P, Walker, A, Wolf, A, Speth, M M, Jacques, T, Hox, V, Van Gerven, L, Santamaria-Gadea, A, Segboer, C, Lourijsen, E, Turri-Zanoni, M, Huart, C, Rennie, C, Green, R, The Samter's Society, The Samter's Society, Kelly, C E, Knill, A, Lund, V J, Fokkens, W J, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hopkins, C, Surda, P, Walker, A, Wolf, A, Speth, M M, Jacques, T, Hox, V, Van Gerven, L, Santamaria-Gadea, A, Segboer, C, Lourijsen, E, Turri-Zanoni, M, Huart, C, Rennie, C, Green, R, The Samter's Society, The Samter's Society, Kelly, C E, Knill, A, Lund, V J, and Fokkens, W J

Abstract

EPOS2020 is the 4th and most recent version of the European Position Paper on Rhinosinusitis and Nasal Polyps which was first published in 2005. It aims to provide the most up to date scientifically robust information on the topic published in the literature which has been critically analysed by an international group of clinicians drawn from all disciplines dealing with these problems together with patients. The guidelines offer evidence-based recommendations and care pathways for acute and chronic rhinosinusitis in both adults and children. Management of these diseases from the patients' perspective is an important part of EPOS2020. Not only is this included in the main document but, for the first time, we have produced a separate supplement dedicated to and in collaboration with patients, EPOS4Patients, which aims to provide information in an accessible format, to answer frequently asked questions about these diseases and their treatment options as well as including useful patient resources and websites. It has never been more important for patients to be actively involved in their care. Being well informed helps you to make the best decisions together with your doctor.

Published
2021

27. EPOS 4 Patients.

Author

UCL - (SLuc) Service d'oto-rhino-laryngologie, Hopkins, C, Surda, P, Walker, A, Wolf, A, Speth, M M, Jacques, T, Hox, V, Van Gerven, L, Santamaria-Gadea, A, Segboer, C, Lourijsen, E, Turri-Zanoni, M, Huart, C, Rennie, C, Green, R, The Samter's Society, The Samter's Society, Kelly, C E, Knill, A, Lund, V J, Fokkens, W J, UCL - (SLuc) Service d'oto-rhino-laryngologie, Hopkins, C, Surda, P, Walker, A, Wolf, A, Speth, M M, Jacques, T, Hox, V, Van Gerven, L, Santamaria-Gadea, A, Segboer, C, Lourijsen, E, Turri-Zanoni, M, Huart, C, Rennie, C, Green, R, The Samter's Society, The Samter's Society, Kelly, C E, Knill, A, Lund, V J, and Fokkens, W J

Abstract

EPOS2020 is the 4th and most recent version of the European Position Paper on Rhinosinusitis and Nasal Polyps which was first published in 2005. It aims to provide the most up to date scientifically robust information on the topic published in the literature which has been critically analysed by an international group of clinicians drawn from all disciplines dealing with these problems together with patients. The guidelines offer evidence-based recommendations and care pathways for acute and chronic rhinosinusitis in both adults and children. Management of these diseases from the patients' perspective is an important part of EPOS2020. Not only is this included in the main document but, for the first time, we have produced a separate supplement dedicated to and in collaboration with patients, EPOS4Patients, which aims to provide information in an accessible format, to answer frequently asked questions about these diseases and their treatment options as well as including useful patient resources and websites. It has never been more important for patients to be actively involved in their care. Being well informed helps you to make the best decisions together with your doctor.

Published
2021

28. Graadmeter Diensten van Natuur, update 2020 : Vraag, aanbod, gebruik en trend van goederen en diensten uit ecosystemen in Nederland

Author

de Knegt, B., van der Aa, M., van Gerven, L., Hendriks, K., Koopmans, S., Lof, M., Riksen, M., Roelofsen, H., de Vries, S., and Woltjer, I.

Subjects
Meteorologie en Luchtkwaliteit, economie van natuurlijke hulpbronnen, vraag, supply, Meteorology and Air Quality, biomassa, Bos- en Landschapsecologie, WASS, Regional Development and Spatial Use, ecosystemen, Biodiversity and Policy, Environmental systems analysis, Political science, aanbod, Biodiversiteit en Beleid, Forest and Landscape Ecology, Duurzaam Bodemgebruik, Vegetatie, Sustainable Soil Use, WIMEK, Vegetation, biomass, natural resource economics, ecosysteemdiensten, biobased economy, demand, Regionale Ontwikkeling en Ruimtegebruik, Bodemfysica en Landbeheer, PE&RC, hout, ComputingMilieux_GENERAL, Soil Physics and Land Management, Environmental Systems Analysis, Milieusysteemanalyse, Vegetatie, Bos- en Landschapsecologie, Vegetation, Forest and Landscape Ecology, ecosystem services, ecosystems, Humanities, wood
Abstract

Dutch society makes use of a variety of goods and services provided by ecosystems – generally referred to as ecosystem services. A visible record of the status and trends in ecosystem services can help government and industry to incorporate the interests of nature and the environment in the Netherlands into decisionmaking processes. The results show that although Dutch ecosystems make a valuable contribution towards the need for the sustainable provision of goods and services, they do not satisfy the entire demand. Moreover, over the past 20 years the demand for most ecosystem services has risen faster than the supply. De Nederlandse samenleving gebruikt verschillende goederen en diensten die ecosystemen leveren – de zogeheten ecosysteemdiensten. Het zichtbaar maken van de toestand en trends van ecosysteemdiensten in Nederland kan helpen bij de oordeelsvorming en besluitvorming van natuur in Nederland door de overheid en het bedrijfsleven. Resultaten laten zien dat, alhoewel Nederlandse ecosystemen een belangrijke bijdrage leveren aan de behoefte aan een duurzame voorziening van goederen en diensten, ze niet voorzien in de totale vraag. Bovendien geldt dat voor de meerderheid van de ecosysteemdiensten de vraag ernaar sneller toeneemt dan het aanbod in de afgelopen twintig jaar.

Published
2020

31. The intranasal trigeminal system: roles in rhinitis (allergic and non-allergic).

Author

ULUSOY, S., MULUK, N. BAYAR, SCADDING, G. K., PASSALI, G. S., DILBER, M., GEVAERT, P., PASSALI, D., RESULI, A. S., VAN GERVEN, L., KALOGJERA, L., PROKOPAKIS, E., ROMBAUX, P., HELLINGS, P., and CINGI, C. C.

Abstract

The aim of this paper is to review intranasal trigeminal system and associated reflexes. The literature survey was performed on PubMed, ProQuest Central database of Kirikkale University and Google Scholar. The intranasal trigeminal system and associated reflexes play an important role in humans in both health and disease, including in rhinitis of non-allergic and mixed type. The intranasal trigeminal nerve provides sensory perception to the lining of the nose, supplying information on how patent the nasal airway is and responding to various chemical signals. The reflexes known to exist within the intranasal trigeminal system are nasobronchial reflex, trigemino-cardiac reflex, nasogastric reflex, and nasal cycle. The intranasal trigeminal system and its reflexes play a vital role in normal human physiology. Alterations in how this system operates may underlie multiple forms of rhinitis and more research is needed to fully understand the mechanisms involved. [ABSTRACT FROM AUTHOR]

Published
2022

32. Surgical closure of nasoseptal perforations: predictive factors for success

Author

Dierickx, C, Van Gerven, L, and Jorissen, M

Subjects
NASAL SEPTAL PERFORATION, Science & Technology, Otorhinolaryngology, Nasal mucosa, nasal surgical procedure, Life Sciences & Biomedicine, acquired nose deformities
Abstract

ispartof: B-ENT vol:15 issue:3 pages:161-167 status: published

Published
2019

37. SIOG2021-0018 - Differences in treatment and survival of older patients with operable breast cancer between the United Kingdom and the Netherlands – a comparison of two national prospective longitudinal multi-centre cohort studies

Author

van der Plas-Krijgsman, W., Morgan, J., de Glas, N., de Boer, A., Martin, C., Holmes, G., Ward, S., Chater, T., Reed, M., Merkus, J., van Dalen, T., Vulink, A., van Gerven, L., Guicherit, O., Linthorst, E., Bastiaannet, E., Portielje, J., Liefers, G.J., and Wyld, L.

Published
2021
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40. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology

Author

Hellings, P.W. Klimek, L. Cingi, C. Agache, I. Akdis, C. Bachert, C. Bousquet, J. Demoly, P. Gevaert, P. Hox, V. Hupin, C. Kalogjera, L. Manole, F. Mösges, R. Mullol, J. Muluk, N.B. Muraro, A. Papadopoulos, N. Pawankar, R. Rondon, C. Rundenko, M. Seys, S.F. Toskala, E. Van Gerven, L. Zhang, L. Zhang, N. Fokkens, W.J.

Abstract

This EAACI position paper aims at providing a state-of-the-art overview on nonallergic rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined as nonallergic noninfectious rhinitis (NANIR) patients, often denominated in short as having NAR. NAR is defined as a symptomatic inflammation of the nasal mucosa with the presence of a minimum of two nasal symptoms such as nasal obstruction, rhinorrhea, sneezing, and/or itchy nose, without clinical evidence of endonasal infection and without systemic signs of sensitization to inhalant allergens. Symptoms of NAR may have a wide range of severity and be either continuously present and/or induced by exposure to unspecific triggers, also called nasal hyperresponsiveness (NHR). NHR represents a clinical feature of both AR and NAR patients. NAR involves different subgroups: drug-induced rhinitis, (nonallergic) occupational rhinitis, hormonal rhinitis (including pregnancy rhinitis), gustatory rhinitis, senile rhinitis, and idiopathic rhinitis (IR). NAR should be distinguished from those rhinitis patients with an allergic reaction confined to the nasal mucosa, also called “entopy” or local allergic rhinitis (LAR). We here provide an overview of the current consensus on phenotypes of NAR, recommendations for diagnosis, a treatment algorithm, and defining the unmet needs in this neglected area of research. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Published
2017

41. EUFOREA Rhinology Research Forum 2016: report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis

Author

Hellings, PW, Akdis, CA, Bachert, C, Bousquet, J, Pugin, B, Adriaensen, G, Advani, R, Agache, I, Anjo, C, Anmolsingh, R, Annoni, E, Bieber, T, Bizaki, A, Braverman, I, Callebaut, I, Castillo Vizuete, JA, Chalermwatanachai, T, Chmielewski, R, Cingi, C, Cools, L, Coppije, C, Cornet, M, De Boeck, I, De Corso, E, De Greve, G, Doulaptsi, M, Erskine, S, Gevaert, E, Gevaert, P, Golebski, K, Hopkins, C, Hox, V, Jaeggi, C, Joos, G, Khwaja, S, Kjeldsen, A, Klimek, L, Koennecke, M, Kortekaas Krohn, I, Krysko, O, Kumar, BN, Langdon, C, Lange, B, Lekakis, G, Levie, P, Lourijsen, E, Lund, V, Martens, K, Mösges, R, Mullol, J, Nyembue, TD, Palkonen, S, Philpott, C, Pimentel, J, Poirrier, A, Pratas, AC, Prokopakis, E, Pujols, L, Rombaux, P, Schmidt-Weber, C, Segboer, C, Spacova, I, Staikuniene, J, Steelant, B, Steinsvik, EA, Teufelberger, A, Van Gerven, L, Van Gool, K, Verbrugge, R, Verhaeghe, B, Virkkula, P, Vlaminck, S, Vries-Uss, E, Wagenmann, M, Zuberbier, T, Seys, SF, and Fokkens, WJ

Abstract

The first European Rhinology Research Forum organized by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) was held in the Royal Academy of Medicine in Brussels on 17th and 18th November 2016, in collaboration with the European Rhinologic Society (ERS) and the Global Allergy and Asthma European Network (GA2LEN). One hundred and thirty participants (medical doctors from different specialties, researchers, as well as patients and industry representatives) from 27 countries took part in the multiple perspective discussions including brainstorming sessions on care pathways and research needs in rhinitis and rhinosinusitis. The debates started with an overview of the current state of the art, including weaknesses and strengths of the current practices, followed by the identification of essential research needs, thoroughly integrated in the context of Precision Medicine (PM), with personalized care, prediction of success of treatment, participation of the patient and prevention of disease as key principles for improving current clinical practices. This report provides a concise summary of the outcomes of the brainstorming sessions of the European Rhinology Research Forum 2016.

Published
2017

42. mySinusitisCoach: patient empowerment in chronic rhinosinusitis using mobile technology

Author

Seys, S.F., primary, Bousquet, J., additional, Bachert, C., additional, Fokkens, W.J., additional, Agache, I., additional, Bernal-Sprekelsen, M., additional, Callebaut, I., additional, Cardel, L.O., additional, Carrie, S., additional, Castelnuovo, P., additional, Cathcart, R., additional, Constantinidis, J., additional, Cools, L., additional, Cornet, M., additional, Clement, G., additional, de Sousa, J.C., additional, Cox, T., additional, Doulaptsi, M., additional, Gevaert, P., additional, Hopkins, C., additional, Hox, V., additional, Hummel, T., additional, Hosemann, W., additional, Jacobs, R., additional, Jorissen, M., additional, Landis, B.N., additional, Leunig, A., additional, Lund, V.J., additional, Mullol, J., additional, Onerci, M., additional, Palkonen, S., additional, Proano, I., additional, Prokopakis, E., additional, Ryan, D., additional, Riechelmann, H., additional, Saevels, J., additional, Segboer, C., additional, Speleman, K., additional, Steinsvik, E.A., additional, Surda, P., additional, Tomazic, P.V., additional, Vanderveken, O., additional, Van Gerven, L., additional, Van Zele, T., additional, Verhaeghe, B., additional, Vierstraete, K., additional, Vlaminck, S., additional, Wilkinson, J., additional, Williams, S., additional, Pugin, B., additional, and Hellings, P.W., additional

Published
2018
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45. EUFOREA Rhinology Research Forum 2017: report of the brainstorming sessions on endotype-driven treatment, patient empowerment and digital future in airways care

Author

Lund, V.J., primary, Hopkins, C., additional, Akdis, C., additional, Bachert, C., additional, Bousquet, J., additional, Fokkens, W.J., additional, Seys, S., additional, Van Gerven, L., additional, Akdis, M., additional, Ban, G.Y., additional, Biswas, K., additional, Boscke, R., additional, Boeva, V., additional, Canonica, G.W., additional, Castillo, J.A., additional, Chung, S.K., additional, Claes, J.A.M., additional, Cools, L., additional, De Carlo, G., additional, De Corso, E., additional, Djandji, M., additional, Doulaptsi, M., additional, Feijen, J., additional, Gallo, S., additional, Gane, S., additional, Gevaert, P., additional, Golebski, K., additional, Halewyck, S., additional, Hummel, T., additional, Izquierdo, I., additional, Jagerschmidt, A., additional, Joos, G.F., additional, Kjeldsen, A.D., additional, Kloeck, I., additional, Koennecke, M., additional, Kokorina, O., additional, Koren, I., additional, Kortekaas-Krohn, I., additional, Krysko, O., additional, Landis, B.N., additional, Lange, B., additional, Launders, N., additional, Lee, J., additional, Lekakis, G., additional, Mannent, L., additional, Martens, K., additional, Morghenti, D., additional, Mullol, J., additional, Murray, R., additional, O'Sullivan, D., additional, Philpott, C., additional, Popov, T.A., additional, Prokopakis, E., additional, Rombaux, P., additional, Rondon, C., additional, Rowe, P.J., additional, Seyed-Tabib, N.S., additional, Sleurs, K., additional, Speleman, K.J.S., additional, Staikuniene, J., additional, Steelant, B., additional, Talavera-Perez, K., additional, Taube, C., additional, Toppila-Salmi, S., additional, Tran-Le, T., additional, Vaitkus, J., additional, Vaitkus, S., additional, Van Gool, K., additional, Van Hoolst, A., additional, Verbrugge, R., additional, Verhaeghe, B., additional, Vlaminck, S., additional, Wagenmann, M., additional, Zuberbier, T., additional, Tasman, A.-J., additional, Pugin, B., additional, and Hellings, P.W., additional

Published
2018
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47. EUFOREA Rhinology Research Forum 2016: report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis

Author

Hellings, P. W., Akdis, C. A., Bachert, C., Bousquet, J., Pugin, B., Adriaensen, G., Advani, R., Agache, I., Anjo, C., Anmolsingh, R., Annoni, E., Bieber, T., Bizaki, A., Braverman, I., Callebaut, I., Castillo Vizuete, J. A., Chalermwatanachai, T., Chmielewski, R., Cingi, C., Cools, L., Coppije, C., Cornet, M. E., De Boeck, I., De Corso, E., De Greve, G., Doulaptsi, M., Edmiston, R., Erskine, S., Gevaert, E., Gevaert, P., Golebski, K., Hopkins, C., Hox, V., Jaeggi, C., Joos, G., Khwaja, S., Kjeldsen, A., Klimek, L., Koennecke, M., Krohn, I. Kortekaas, Krysko, O., Kumar, B. N., Langdon, C., Lange, B., Lekakis, G., Levie, P., Lourijsen, E., Lund, V. J., Martens, K., Moesges, R., Mullol, J., Nyembue, T. D., Palkonen, S., Philpott, C., Pimentel, J., Poirrier, A., Pratas, A. C., Prokopakis, E., Pujols, L., Rombaux, P., Schmidt-Weber, C., Segboer, C., Spacova, I., Staikuniene, J., Steelant, B., Steinsvik, E. A., Teufelberger, A., Van Gerven, L., Van Gool, K., Verbrugge, R., Verhaeghe, B., Virkkula, P., Vlaminck, S., Vries-Uss, E., Wagenmann, M., Zuberbier, T., Seys, S. F., Fokkens, W. J., Hellings, P. W., Akdis, C. A., Bachert, C., Bousquet, J., Pugin, B., Adriaensen, G., Advani, R., Agache, I., Anjo, C., Anmolsingh, R., Annoni, E., Bieber, T., Bizaki, A., Braverman, I., Callebaut, I., Castillo Vizuete, J. A., Chalermwatanachai, T., Chmielewski, R., Cingi, C., Cools, L., Coppije, C., Cornet, M. E., De Boeck, I., De Corso, E., De Greve, G., Doulaptsi, M., Edmiston, R., Erskine, S., Gevaert, E., Gevaert, P., Golebski, K., Hopkins, C., Hox, V., Jaeggi, C., Joos, G., Khwaja, S., Kjeldsen, A., Klimek, L., Koennecke, M., Krohn, I. Kortekaas, Krysko, O., Kumar, B. N., Langdon, C., Lange, B., Lekakis, G., Levie, P., Lourijsen, E., Lund, V. J., Martens, K., Moesges, R., Mullol, J., Nyembue, T. D., Palkonen, S., Philpott, C., Pimentel, J., Poirrier, A., Pratas, A. C., Prokopakis, E., Pujols, L., Rombaux, P., Schmidt-Weber, C., Segboer, C., Spacova, I., Staikuniene, J., Steelant, B., Steinsvik, E. A., Teufelberger, A., Van Gerven, L., Van Gool, K., Verbrugge, R., Verhaeghe, B., Virkkula, P., Vlaminck, S., Vries-Uss, E., Wagenmann, M., Zuberbier, T., Seys, S. F., and Fokkens, W. J.

Abstract

The first European Rhinology Research Forum organized by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) was held in the Royal Academy of Medicine in Brussels on 17th and 18th November 2016, in collaboration with the European Rhinologic Society (ERS) and the Global Allergy and Asthma European Network (GA2LEN). One hundred and thirty participants (medical doctors from different specialties, researchers, as well as patients and industry representatives) from 27 countries took part in the multiple perspective discussions including brainstorming sessions on care pathways and research needs in rhinitis and rhinosinusitis.The debates started with an overview of the current state of the art, including weaknesses and strengths of the current practices, followed by the identification of essential research needs, thoroughly integrated in the context of Precision Medicine (PM), with personalized care, prediction of success of treatment, participation of the patient and prevention of disease as key principles for improving current clinical practices. This report provides a concise summary of the outcomes of the brainstorming sessions of the European Rhinology Research Forum 2016.

Published
2017

50. FABM-PCLake - linking aquatic ecology with hydrodynamics: Model description paper

Author

Hu, F., Bolding, K., Bruggeman, J., Jeppesen, E., Flindt, M. R., van Gerven, L., Janse, J. H., Janssen, A. B. G., Kuiper, J. J., Mooij, W. M., Trolle, D., and Aquatic Ecology (AqE)

Subjects
international
Abstract

This study presents FABM-PCLake, a complete redesign of the PCLake aquatic ecosystem model, which we implemented into the Framework for Aquatic Biogeochemical Models (FABM). In contrast to the original model, which was designed for temperate, fully mixed freshwater lakes, the new FABM-PCLake represents an integrated aquatic ecosystem model that enables simulations of hydrodynamics and biogeochemical processes for zero dimensional, one-dimensional as well as three-dimensional heterogeneous environments. FABM-PCLake describes interactions between multiple trophic levels, including piscivorous, zooplanktivorous and benthivorous fish, zooplankton, zoobenthos, three groups of phytoplankton and rooted macrophytes. The model also accounts for oxygen dynamics and nutrient cycling for nitrogen, phosphorus and silicon, both within the pelagic and benthic domains. FABM-PCLake includes a two-way communication between the biogeochemical processes and the physics, where some biogeochemical state variables (e.g., phytoplankton) influence light attenuation and thereby the spatial and temporal distributions of light and heat. At the same time, the physical environment, including water currents, light and temperature influence a wide range of biogeochemical processes. The model enables studies on ecosystem dynamics in physically heterogeneous environments (e.g., stratifying water bodies, and water bodies with horizontal gradient in physical and biogeochemical properties), and through FABM also enables data assimilation and multi-model ensemble simulations. Examples of relevant model applications include climate change impact studies and environmental impact assessment scenarios for lakes and reservoirs worldwide.

Published
2016

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