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1. Higher Annual Operator Volume Is Associated With Better Reperfusion Rates in Stroke Patients Treated by Mechanical Thrombectomy: The ETIS Registry

Author

Piotin, Michel, Blanc, Raphaël, Redjem, Hocine, Escalard, Simon, Desilles, Jean-Philippe, Ciccio, Gabriele, Smajda, Stanislas, Mazighi, Mikael, Fahed, Robert, Obadia, Michael, Sabben, Candice, Corabianu, Ovide, de Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre-Yves, Taylor, Guillaume, Ben Maacha, Malek, Bourdain, Frédéric, Decroix, Jean-Pierre, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Lapergue, Bertrand, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesch, Georges, Leguen, Morgan, Tisserand, Marie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Gory, Benjamin, Labeyrie, Paul Emile, Riva, Roberto, Turjman, Francis, Nighoghossian, Norbert, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Lukaszewicz, Anne-Claire, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne-Evelyne, El Nawar, Rody, Blanc, Raphael, Bourdain, Frederic, Kyheng, Maéva, and Labreuche, Julien

Published
2019
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3. Impact of Reperfusion for Nonagenarians Treated by Mechanical Thrombectomy: Insights From the ETIS Registry

Author

Drouard-de Rousiers, Eve, Lucas, Ludovic, Richard, Sébastien, Consoli, Arturo, Mazighi, Mikaël, Labreuche, Julien, Kyheng, Maéva, Gory, Benjamin, Dargazanli, Cyril, Arquizan, Caroline, Marnat, Gaultier, Blanc, Raphaël, Desal, Hubert, Bourcier, Romain, Sibon, Igor, Lapergue, Bertrand, Piotin, Michel, Blanc, Raphaël, Redjem, Hocine, Escalard, Simon, Desilles, Jean-Philippe, Redjem, Hocine, Ciccio, Gabriele, Smajda, Stanislas, Mazighi, Mikaël, Fahed, Robert, Obadia, Mikael, Sabben, Candice, Corabianu, Ovide, de Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre-Yves, Taylor, Guillaume, Maacha, Malek Ben, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Afanasiev, Vadim, Ajili, Nadia, Sensenbrenner, Bénédicte, Lapergue, Bertrand, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesch, Georges, Del Sette, Bruno, Russo, Riccardo, Mizutani, Katsuhiro, Leguen, Morgan, Gratieux, Julie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Nighoghossian, Norbert, Riva, Roberto, Eker, Omer, Turjman, Francis, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Lukaszewicz, Anne Claire, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne-Evelyne, Marnat, Gaultier, Gariel, Florent, Barreau, Xavier, Berge, Jérôme, Veunac, Louis, Menegon, Patrice, Sibon, Igor, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Bourcier, Romain, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre-Louis, Roy, Monica, Lenoble, Cédric, L’allinec, Vincent, Girot, Jean-Baptiste, Desal, Hubert, de Gaalon, Solène, Guillon, Benoit, Gory, Benjamin, Bracard, Serge, Anxionnat, René, Braun, Marc, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean-Christophe, Bonnerot, Mathieu, Riou-Comte, Nolwenn, Costa, Isabelle, Chatelain, Anne, Costalat, Vincent, Arquizan, Caroline, Dargazanli, Cyril, Gascou, Grégory, Lefèvre, Pierre-Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, et Lucas Corti, Isabelle Mourand, Francois, Eugene, and Vannier, Stéphane

Published
2019
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4. Successful thrombectomy is beneficial in patients with pre-stroke disability: Results from an international multicenter cohort study

Author

Ducroux, Célina, primary, Derex, Laurent, additional, Nourredine, Mikaïl, additional, Haesebaert, Julie, additional, Buisson, Marielle, additional, Alesefir, Walid, additional, Boisseau, William, additional, Daneault, Nicole, additional, Deschaintre, Yan, additional, Diestro, Jose Danilo B., additional, Eker, Omer, additional, Eneling, Johanna, additional, Gioia, Laura C., additional, Iancu, Daniella, additional, Jacquin, Grégory, additional, Odier, Céline, additional, Stapf, Christian, additional, Raymond, Jean, additional, Roy, Daniel, additional, Weill, Alain, additional, Lapergue, Bertrand, additional, Poppe, Alexandre Y., additional, Piotin, Michel, additional, Blanc, Raphael, additional, Escalard, Hocine Redjem Simon, additional, Desilles, Jean-Philippe, additional, Delvoye, François, additional, Smajda, Stanislas, additional, Maier, Benjamin, additional, Hebert, Solène, additional, Mazighi, Mikael, additional, Obadia, Mikael, additional, Sabben, Candice, additional, Seners, Pierre, additional, Raynouard, Igor, additional, Corabianu, Ovide, additional, de Broucker, Thomas, additional, Manchon, Eric, additional, Taylor, Guillaume, additional, Ben Maacha, Malek, additional, Thion, Laurie-Anne, additional, Lecler, Augustin, additional, Savatovsky, Julien, additional, Wang, Adrien, additional, Evrard, Serge, additional, Tchikviladze, Maya, additional, Ajili, Nadia, additional, Weisenburger-Lile, David, additional, Gorza, Lucas, additional, Buard, Géraldine, additional, Coskun, Oguzhan, additional, Consoli, Arturo, additional, Di Maria, Federico, additional, Rodesh, Georges, additional, Zimatore, Sergio, additional, Leguen, Morgan, additional, Gratieux, Julie, additional, Pico, Fernando, additional, Rakotoharinandrasana, Haja, additional, Tassan, Philippe, additional, Poll, Roxanna, additional, Marinier, Sylvie, additional, Nighoghossian, Norbert, additional, Riva, Roberto, additional, Turjman, Francis, additional, Cho, Tae-Hee, additional, Mechtouff, Laura, additional, Lukaszewicz, Anne Claire, additional, Philippeau, Frédéric, additional, Cakmak, Serkan, additional, Blanc-Lasserre, Karine, additional, Vallet, Anne-Evelyne, additional, Marnat, Gaultier, additional, Gariel, Florent, additional, Barreau, Xavier, additional, Berge, Jérôme, additional, Menegon, Patrice, additional, Sibon, Igor, additional, Lucas, Ludovic, additional, Olindo, Stéphane, additional, Renou, Pauline, additional, Sagnier, Sharmila, additional, Poli, Mathilde, additional, Debruxelles, Sabrina, additional, Rouanet, François, additional, Tourdias, Thomas, additional, Liegey, Jean-Sebastien, additional, Briau, Pierre, additional, Pangon, Nicolas, additional, Bourcier, Romain, additional, Detraz, Lili, additional, Daumas-Duport, Benjamin, additional, Alexandre, Pierre-Louis, additional, Roy, Monica, additional, Lenoble, Cédric, additional, Desal, Hubert, additional, Guillon, Benoît, additional, de Gaalon, Solène, additional, Preterre, Cécile, additional, Gory, Benjamin, additional, Bracard, Serge, additional, Anxionnat, René, additional, Braun, Marc, additional, Derelle, Anne-Laure, additional, Tonnelet, Romain, additional, Liao, Liang, additional, Zhu, François, additional, Schmitt, Emmanuelle, additional, Planel, Sophie, additional, Richard, Sébastien, additional, Humbertjean, Lisa, additional, Mione, Gioia, additional, Lacour, Jean-Christophe, additional, Riou-Comte, Nolwenn, additional, Audibert, Gérard, additional, Voicu, Marcela, additional, Alb, Ionel, additional, Reitter, Marie, additional, Brezeanu, Madalina, additional, Masson, Agnès, additional, Tabarna, Adriana, additional, Podar, Iona, additional, Macian-montoro, Francisco, additional, Saleme, Suzanna, additional, Mounayer, Charbel, additional, Rouchaud, Aymeric, additional, Costalat, Vincent, additional, Arquizan, Caroline, additional, Dargazanli, Cyril, additional, Gascou, Grégory, additional, Lefèvre, Pierre-Henri, additional, Derraz, Imad, additional, Riquelme, Carlos, additional, Gaillard, Nicolas, additional, Mourand, Isabelle, additional, Corti, Lucas, additional, Cagnazzo, Federico, additional, ter Schiphorst, Adrien, additional, Francois, Eugene, additional, Vannier, Stéphane, additional, Ferre, Jean-christophe, additional, Raoult, Helene, additional, Ronziere, Thomas, additional, Lassale, Maria, additional, Paya, Christophe, additional, Gauvrit, Jean-Yves, additional, Tracol, Clément, additional, Langnier-Lemercier, Sophie, additional, Samson, Yves, additional, Rosso, Charlotte, additional, Leger, Anne, additional, Deltour, Sandrine, additional, Clarencon, Frederic, additional, Shotar, Eimad, additional, Spelle, Laurent, additional, Denier, Christian, additional, Chassin, Olivier, additional, Chalumeau, Vanessa, additional, Caroff, Jildaz, additional, Venditti, Laura, additional, Naggara, Olivier, additional, Hassen, Wagih Ben, additional, Boulouis, Grégoire, additional, Rodriguez-Régent, Christine, additional, Trystram, Denis, additional, Kerleroux, Basile, additional, Turc, Guillaume, additional, Domigo, Valérie, additional, Lamy, Catherine, additional, Birchenall, Julia, additional, Isabel, Clothilde, additional, Lun, François, additional, Viguier, Alain, additional, Cognard, Christophe, additional, Januel, Anne Christine, additional, Olivot, Jean-Marc, additional, Raposo, Nicolas, additional, Bonneville, Fabrice, additional, Albucher, Jean François, additional, Calviere, Lionel, additional, Darcourt, Jean, additional, Tall, Philippe, additional, Bellanger, Guillaume, additional, Fontaine, Louis, additional, Touze, Emmanuel, additional, Barbier, Charlotte, additional, Schneckenburger, Romain, additional, Boulanger, Marion, additional, Cogez, Julien, additional, Guettier, Sophie, additional, Timsit, Serge, additional, Gentric, Jean-christophe, additional, Ognard, Julien, additional, Merrien, Francois Mathias, additional, Wermester, Ozlem Ozkul, additional, Massardier, Evelyne, additional, Papagiannaki, Chrysanthi, additional, Bourdain, Frédéric, additional, Bernady, Patricia, additional, Lagoarde-Segot, Laurent, additional, Cailliez, Hélène, additional, Veunac, Louis, additional, Higue, David, additional, Wolff, Valérie, additional, Pop, Raoul, additional, Beaujeux, Rémi, additional, Dan-Sorin, Mihoc, additional, Manisor, Monica, additional, Le Bras, Anthony, additional, Evain, Sarah, additional, Le Guen, Arnaud, additional, Richter, Sebastian, additional, Hubrecht, Regis, additional, Demasles, Stéphanie, additional, Barroso, Bruno, additional, Sablot, Denis, additional, Farouil, Geoffroy, additional, Tardieu, Maxime, additional, Smadja, Philippe, additional, Aptel, Sabine, additional, and Seiler, Ian, additional

Published
2023
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5. Acute Stroke With Large Ischemic Core Treated by Thrombectomy: Predictors of Good Outcome and Mortality

Author

Panni, Pietro, Gory, Benjamin, Xie, Yu, Consoli, Arturo, Desilles, Jean-Philippe, Mazighi, Mikael, Labreuche, Julien, Piotin, Michel, Turjman, Francis, Eker, Omer Faruk, Bracard, Serge, Anxionnat, René, Richard, Sébastien, Hossu, Gabriela, Blanc, Raphael, Lapergue, Bertrand, Redjem, Hocine, Escalard, Simon, Redjem, Hocine, Ciccio, Gabriele, Smajda, Stanislas, Fahed, Robert, Obadia, Michael, Sabben, Candice, Corabianu, Ovide, de Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre-Yves, Taylor, Guillaume, Maacha, Malek Ben, Bourdain, Frédéric, Decroix, Jean-Pierre, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Coskun, Oguzhan, Di Maria, Federico, Rodesh, Georges, Leguen, Morgan, Tisserand, Marie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Nighoghossian, Norbert, Labeyrie, Paul Emile, Riva, Roberto, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Claire Lukaszewicz, Anne, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, and Vallet, Anne-Evelyne

Published
2019
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6. Improving Access to Thrombolysis and Inhospital Management Times in Ischemic Stroke: A Stepped-Wedge Randomized Trial

Author

Haesebaert, Julie, Nighoghossian, Norbert, Mercier, Catherine, Termoz, Anne, Porthault, Sylvie, Derex, Laurent, Gueugniaud, Pierre-Yves, Bravant, Estelle, Rabilloud, Muriel, Schott, Anne-Marie, Saligari, Elisabeth, Cailler, Samira, Hénniche, Adeline, Prost, Sylvain, Fournier, Carole, Le Loch, Jean-Baptiste, Roncoroni, Cécile, Verbois, Frédéric, Debas, Olivier, Tesniere, Marc, Bontemps, Béatrice, Lavignon, Jean-Pierre, Rimet, Mathilde, Trinquet, Patricia, Millot, Thomas, Dumont, Odile, Tabyaoui, Samir, Ziade, Elie, Detante, Olivier, Giroud, Maurice, Cakmak, Serkan, Marcel, Sébastien, Blanc-Lasserre, Karine, Minier, Dominique, Rodier, Gilles, Philippeau, Frédéric, and Vallet, Anne-Evelyne

Published
2018
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7. Impact of Prior Antiplatelet Therapy on Outcomes After Endovascular Therapy for Acute Stroke: Endovascular Treatment in Ischemic Stroke Registry Results

Author

Couture, Marie, primary, Finitsis, Stephanos, additional, Marnat, Gaultier, additional, Richard, Sébastien, additional, Bourcier, Romain, additional, Constant-dits-Beaufils, Pacôme, additional, Dargazanli, Cyril, additional, Arquizan, Caroline, additional, Mazighi, Mikaël, additional, Blanc, Raphaël, additional, Eugène, François, additional, Vannier, Stéphane, additional, Spelle, Laurent, additional, Denier, Christian, additional, Touzé, Emmanuel, additional, Barbier, Charlotte, additional, Saleme, Suzana, additional, Macian, Francisco, additional, Rosso, Charlotte, additional, Clarençon, Frédéric, additional, Naggara, Olivier, additional, Turc, Guillaume, additional, Ozkul-Wermester, Ozlem, additional, Papagiannaki, Chrysanthi, additional, Viguier, Alain, additional, Cognard, Christophe, additional, Lebras, Anthony, additional, Evain, Sarah, additional, Wolff, Valérie, additional, Pop, Raoul, additional, Timsit, Serge, additional, Gentric, Jean-Christophe, additional, Bourdain, Frédéric, additional, Veunac, Louis, additional, Lapergue, Bertrand, additional, Consoli, Arturo, additional, Gory, Benjamin, additional, Sibon, Igor, additional, Piotin, Michel, additional, Redjem, Hocine, additional, Escalard, Simon, additional, Dessilles, Jean-Philippe, additional, Delvoye, François, additional, Smajda, Stanislas, additional, Maier, Benjamin, additional, Solène, Hebert, additional, Obadia, Mikael, additional, Sabben, Candice, additional, Seners, Pierre, additional, Raynouard, Igor, additional, Corabianu, Ovide, additional, de Broucker, Thomas, additional, Manchon, Eric, additional, Taylor, Guillaume, additional, Ben Maacha, Malek, additional, Thion, Laurie-Anne, additional, Lecler, Augustin, additional, Savatovsjy, Julien, additional, Wang, Adrien, additional, Evrard, Serge, additional, Tchikviladze, Maya, additional, Ajili, Nadia, additional, WeisenburgerLile, David, additional, Gorza, Lucas, additional, Buard, Géraldine, additional, Coskun, Oguzhan, additional, Di Maria, Federico, additional, Rodesh, Georges, additional, Zimatore, Sergio, additional, Leguen, Morgan, additional, Gratieux, Julie, additional, Pico, Fernando, additional, Rakotoharinandrasana, Haja, additional, Tassan, Philippe, additional, Poll, Roxanna, additional, Marinier, Sylvie, additional, Gariel, Florent, additional, Barreau, Xavier, additional, Berge, Jérôme, additional, Menegon, Patrice, additional, Lucas, Ludovic, additional, Olindo, Stéphane, additional, Renou, Pauline, additional, Sagnier, Sharmila, additional, Poli, Mathilde, additional, Debruxelles, Sabrina, additional, Rouanet, François, additional, Tourdias, Thomas, additional, Liegey, Jean-Sebastien, additional, Briau, Pierre, additional, Pangon, Nicolas, additional, Detraz, Lili, additional, Daumas-Duport, Benjamin, additional, Alexandre, Pierre-Louis, additional, Roy, Monica, additional, Lenoble, Cédric, additional, Desal, Hubert, additional, Guillon, Benoît, additional, de Gaalon, Solène, additional, Preterre, Cécile, additional, Bracard, Serge, additional, Anxionnat, René, additional, Braun, Marc, additional, Derelle, Anne-Laure, additional, Liao, Liang, additional, Tonnelet, Romain, additional, Liao, François, additional, Zhu, Emmanuelle, additional, Schmitt, Sophie, additional, Planel, Sébastien, additional, Richard, Lisa, additional, Humbertjean, Gioia, additional, Mione, Jean-Christophe, additional, Lacour, Nolwenn, additional, Riou-Comte, Gérard, additional, Audibert, Marcela, additional, Voicu, Lionel, additional, Alb, Marie, additional, Reitter, Madalina, additional, Brezeanu, Agnès, additional, Masson, Adriana, additional, Tabarna, Iona, additional, Podar, Sarah, additional, Guy, Fatiha, additional, Bechiri, Fatiha, additional, Mounayer, Charbel, additional, Rouchaud, Aymeric, additional, Gimenez, Laetitia, additional, Cosnard, Alexandre, additional, Costalat, Vincent, additional, Gascou, Grégory, additional, Lefèvre, Pierre-Henri, additional, Derraz, Imad, additional, Riquelme, Carlos, additional, Gaillard, Nicolas, additional, Mourand, Isabelle, additional, Corti, Lucas, additional, Cagnazzo, Federico, additional, ter Schiphorst, Adrien, additional, Ferre, Jean-Christophe, additional, Raoult, Hélène, additional, Ronziere, Thomas, additional, Lassale, Maria, additional, Paya, Christophe, additional, Gauvrit, Jean-Yves, additional, Tracol, Clément, additional, Maurice, Sophie Langnier-Lemercier, Axelle, additional, Cochennec, Sabrina, additional, Pinault, Mélanie, additional, Shotar, Eimad, additional, Sourour, Nader, additional, Lenck, Stéphanie, additional, Premat, Kévin, additional, Anne Léger, Yves Samson, additional, Crozier, Sophie, additional, Baronnet, Flore, additional, Alamowitch, Sonia, additional, Bottin, Laure, additional, Yger, Mathon, additional, Degos, Vincent, additional, Chassin, Olivier, additional, Chalumeau, Vanessa, additional, Caroff, Jildaz, additional, Venditti, Laura, additional, Sarov, Mariana, additional, Legris, Nicolas, additional, Hassen, Wagih Ben, additional, Boulouis, Grégoire, additional, Rodriguez-Régent, Christine, additional, Trystram, Denis, additional, Kerleroux, Basile, additional, Domigo, Valérie, additional, Lamy, Catherine, additional, Birchenall, Julia, additional, Isabel, Clothilde, additional, Lun, François, additional, Januel, Anne Christine, additional, Olivot, Jean-Marc, additional, Raposo, Nicolas, additional, Bonneville, Fabrice, additional, Albucher, Jean François, additional, Calviere, Lionel, additional, Darcourt, Jean, additional, Bellanger, Guillaume, additional, Tall, Philippe, additional, Schneckenburger, Romain, additional, Boulanger, Marion, additional, Cogez, Julien, additional, Guettier, Sophie, additional, Gauberti, Maxime, additional, Ognard, Julien, additional, Mathias Merrien., Francois, additional, Wermester, Ozlem Ozku, additional, Massardier, Evelyne, additional, Triquenot, Aude, additional, Lefebvre, Margeaux, additional, Bernady, Patricia, additional, Lagoarde-Segot, Laurent, additional, Cailliez, Hélène, additional, Higue, David, additional, Quenardelle, Veronique, additional, Lauer, Valerie, additional, Gheoca, Roxana, additional, Pierre-Paul, Irene, additional, Beaujeux, Remy, additional, Mihoc, Dan, additional, Manisor, Monica, additional, Pottecher, Julien, additional, Meyer, Alain, additional, Chamaraux-Tran, Thiên-Nga, additional, Le Bras, Anthony, additional, Le Guen, Arnaud, additional, Nighoghossian, Norbert, additional, Riva, Roberto, additional, Eker, Omer, additional, turjman, Francis, additional, Derex, Laurent, additional, Cho, Tae-Hee, additional, Mechtouff, Laura, additional, Claire Lukaszewicz, Anne, additional, Philippeau, Frédéric, additional, Cakmak, Serkan, additional, Blanc-Lasserre, Karine, additional, and Vallet, Anne-Evelyne, additional

Published
2021
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9. Effect of Operator's Experience on Proficiency in Mechanical Thrombectomy: A Multicenter Study

Author

François Zhu, Wagih Ben Hassen, Nicolas Bricout, Basile Kerleroux, Kevin Janot, Benjamin Gory, René Anxionnat, Sébastien Richard, Adrien Marchal, Raphael Blanc, Michel Piotin, Arturo Consoli, Denis Trystram, Christine Rodriguez Regent, Jean-Philippe Desilles, David Weisenburger-Lile, Simon Escalard, Denis Herbreteau, Heloise Ifergan, Igor Lima Maldonado, Julien Labreuche, Hilde Henon, Olivier Naggara, Bertrand Lapergue, Grégoire Boulouis, Redjem Hocine, Ciccio Gabriele, Smajda Stanislas, Maier Benjamin, Mazighi Mikael, Obadia Mikael, Sabben Candice, Peres Roxanne, Corabianu Ovide, De Broucker Thomas, Smadja Didier, Alamowitch Sonia, Ille Olivier, Manchon Eric, Garcia Pierre-Yves, Taylor Guillaume, Ben Maacha Malek, Wang Adrien, Evrard Serge, Tchikviladze Maya, Ajili Nadia, Gorza Lucas, Buard Géraldine, Coskun Oguzhan, Di Maria Federico, Rodesh Georges, Zimatore Sergio, Leguen Morgan, Gratieux Julie, Pico Fernando, Rakotoharinandrasana Haja, Tassan Philippe, Poll Roxanna, Marinier Sylvie, Nighoghossian Norbert, Riva Roberto, Eker Omer, Turjman Francis, Derex Laurent, Cho Tae-Hee, Mechtouff Laura, Claire Lukaszewicz Anne, Philippeau Frédéric, Cakmak Serkan, Blanc-Lasserre Karine, Vallet Anne-Evelyne, Marnat Gaultier, Gariel Florent, Barreau Xavier, Berge Jérôme, Menegon Patrice, Sibon Igor, Liegey Sebastien, Olindo Stéphane, Renou Pauline, Sagnier Sharmila, Poli Mathilde, Debruxelles Sabrina, Pangon Nicolas, Bourcier Romain, Detraz Lili, Daumas-Duport Benjamin, Alexandre Pierre-Louis, Roy Monica, Lenoble Cédric, L’allinec Vincent, Girot Jean-Baptiste, Desal Hubert, Bracard Serge, Braun Marc, Derelle Anne-Laure, Tonnelet Romain, Liao Liang, Muszynski Patricio, Schmitt Emmanuelle, Planel Sophie, Humbertjean Lisa, Mione Gioia, Lacour Jean-Christophe, Riou-Comte Nolwenn, Audibert Gérard, Voicu Marcela, Alb Ionel, Reitter Marie, Brezeanu Madalina, Masson Agnès, Tabarna Adriana, Podar Ioana, Macian-Montoro Francisco, Saleme Suzanna, Mounayer Charbel, Rouchaud Aymeric, Costalat Vincent, Arquizan Caroline, Dargazanli Cyril, Gascou Grégory, Lefèvre Pierre-Henri, Derraz Imad, Riquelme Carlos, Gaillard Nicolas, Mourand Isabelle, Corti Lucas, Francois Eugene, Vannier Stéphane, Ferre Jean-Christophe, Raoult Helene, Ronziere Thomas, Lassale Maria, Paya Christophe, Gauvrit Jean-Yves, Tracol Clément, Langnier-Lemercier Sophie, Samson Yves, Rosso Charlotte, Leger Anne, Deltour Sandrine, Clarencon Frederic, Shotar Eimad, Spelle Laurent, Denier Christian, Chassin Olivier, Chalumeau Vanessa, Caroff Jildaz, Venditti Laura, Turc Guillaume, Seners Pierre, Domigo Valérie, Lamy Catherine, Birchenall Julia, Isabel Clothilde, Viguier Alain, Cognard Christophe, Christine Januel Anne, Olivot Jean-Marc, Raposo Nicolas, Bonneville Fabrice, François Albucher Jean, Calviere Lionel, Touze Emmanuel, Barbier Charlotte, Schneckenburger Romain, Boulanger Marion, Cogez Julien, Guettier Sophie, Timsit Serge, Gentric Jean-Christophe, Ognard Julien, Mathias Merrien Francois, Ozkul Wermester Ozlem, Massardier Evelyne, Papagiannaki Chrysanthi, Bourdain Frédéric, Patricia Bernady, Lagoarde-Segot Laurent, Cailliez Hélène, Veunac Louis, Higue David, Wolff Valérie, Pop Raoul, Beaujeux Rémi, Mihoc Dan-Sorin, Manisor Monica, Le Bras Anthony, Evain Sarah, Le Guen Arnaud, Richter Sebastian, Hubrecht Regis, Demasles Stéphanie, Barroso Bruno, Zuber Mathieu, Farhat Wassim, Alias Quentin, Lun François, Stenvenoot Delphine, Heinzlef Olivier, Godon Hardy Sylvie, Bohotin Valentin, and Grimaud Jérôme

Subjects
medicine.medical_specialty, Standard of care, Time Factors, Neuroradiologist, 030204 cardiovascular system & hematology, Brain Ischemia, 03 medical and health sciences, 0302 clinical medicine, Operator (computer programming), Medicine, Humans, Registries, Thrombectomy, Advanced and Specialized Nursing, Surgeons, business.industry, Cerebral infarction, Endovascular Procedures, Cerebral Infarction, medicine.disease, Mechanical thrombectomy, Stroke, Multicenter study, Ischemic stroke, Reperfusion, Physical therapy, Neurology (clinical), Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery
Abstract

Background and Purpose: We aimed to evaluate among trained interventional neuroradiologist, whether increasing individual experience was associated with an improvement in mechanical thrombectomy (MT) procedural performance metrics. Methods: Individual MT procedural data from 5 centers of the Endovascular Treatment in Ischemic Stroke registry and 2 additional high-volume stroke centers were pooled. Operator experience was defined for each operator as a continuous variable, cumulating the number of MT procedures performed since January 2015, as MT became standard of care or, if later than this date, since the operator started performing mechanical thrombectomies in autonomy. We tested the associations between operator’s experience and procedural metrics. Results: A total of 4516 procedures were included, performed by 36 operators at 7 distinct centers, with a median of 97.5 endovascular treatment procedures per operator (interquartile range, 57–170.2) over the study period. Higher operator’s experience, analyzed as a continuous variable, was associated with a significantly shorter procedural duration (β estimate, −3.98 [95% CI, −5.1 to −2.8]; P P =0.013). Conclusions: In trained interventional neuroradiologists, increasing experience in MT is associated with significantly shorter procedural duration and better reperfusion rates, with a theoretical ceiling effect observed after around 100 procedures. These results may inform future training and practice guidelines to set minimal experience standards before autonomization, and to set-up operators’ recertification processes tailored to individual case volume and prior experience.

Published
2021

11. Prognosis and risk factors associated with asymptomatic intracranial hemorrhage after endovascular treatment of large vessel occlusion stroke: a prospective multicenter cohort study

Author

Constant Dit Beaufils, Pacôme, Labreuche, Julien, Richard, Śebastien, Fahed, Robert, Desal, Hubert Armand, Piotin, Michel P., Blanc, Raphaël, Redjem, Hocine, Escalard, Simon, Desilles, Jean Philippe, Ciccio, Gabriele, Smajda, Stanislas, Maier, Benjamin, Mazighi, Mikael, Obadia, Mikael, Sabben, Candice, Peres, Roxanne, Corabianu, Ovide, De Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre Yves, Taylor, Guillaume, Ben Maacha, Malek, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Ajili, Nadia, Lapergue, Bertrand, Weisenburger, David, Gorza, Lucas, Buard, Géraldine, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesh, Georges, Zimatore, Sergio, Leguen, Morgan, Gratieux, Julie D., Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Marinier, Sylvie, Nighoghossian, Norbert, Riva, Roberto, Eker, Omer faruk, Turjman, Francis, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Lukaszewicz, Anne Claire, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne Evelyne, Marnat, Gaultier, Gariel, Florent, Barreau, Xavier, Berge, Jerome, Veunac, Louis, Menegon, Patrice, Sibon, Igor, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Tourdias, Thomas, Liegey, Jean Sebastien, Bourcier, Romain, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre Louis, Roy, Monica, Lenoble, Cédric, L’Allinec, Vincent, Girot, Jean Baptiste, Desal, Hubert, Guillon, Benoît, De Gaalon, Solène, Preterre, Cécile, Gory, Benjamin, Bracard, Serge R., Anxionnat, René, Braun, Marc, Derelle, Anne Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean Christophe, Bonnerot, Mathieu, Riou-Comte, Nolwenn, Macian-Montoro, Francisco, Saleme, Suzanna, Mounayer, Charbel, Rouchaud, Aymeric M., Costalat, Vincent, Arquizan, Caroline, Dargazanli, Cyril, Gascou, Grégory, Lefèvre, Pierre Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, Francois, Eugene, Vannier, Stéphane, Ferré, Jean-Christophe, Raoult, Hélène, Ronziere, Thomas, Lassale, Maria, Paya, Christophe, Gauvrit, Jean Yves, Tracol, Clément, Langnier-Lemercier, Sophie, Samson, Yves, Rosso, Charlotte, Leger, Anne, Deltour, Sandrine, Clarencon, Frédéric, Shotar, Eimad, Spelle, Laurent, Denier, Christian, Chalumeau, Vanessa, Caroff, Jildaz, Chassin, Olivier, Venditti, Laura, Turc, G., Naggara, Olivier N., Boulouis, Grégoire, Ben Hassen, Wagih, Seners, Pierre, Viguier, Alain, Cognard, Christophe H., Januel, Anne Christine, Olivot, Jean Marc, Raposo, Nicolas, Bonneville, Fabrice, Touze, Emmanuel, Barbier, Charlotte N., Schneckenburger, Romain, Boulanger, Marion, Cogez, Julien, Guettier, Sophie, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Service Neuroradiologie diagnostique et interventionnelle [Hôpital Foch], Hôpital Foch [Suresnes], Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), P.C.D.B. and J.L. have nothing to disclose. R. Blanc, R. Bourcier, A.C., H.D., F.D.M., R.F., F.G., B. Gory, G.M., C.P., S.R., I.S. and F.Z. have nothing to disclose. M.M. reports personal fees from Amgen, personal fees from Boerhinger, personal fees from Acticor, and personal fees from Air Liquide, outside the submitted work. B.L. reports grants from Stryker, Penumbra and Microventino, outside the submitted work. S.D.G. reports personal fees and non‐financial support from Boerhinger, outside the submitted work. B. Guillon reports personal fees from Boerhinger‐Ingelheim France and Bristol‐Myers‐Squibb, outside the submitted work., Centre hospitalier universitaire de Nantes (CHU Nantes), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Service de neuroradiologie [Suresnes], Service de neurologie [Bordeaux], CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Département de Neuro-Radiologie [Bordeaux] (DNR - Bordeaux), CHU Bordeaux [Bordeaux], Service de neurologie [CHRU Nancy], Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), and The Ottawa Hospital

Subjects
Male, endovascular treatment, medicine.medical_specialty, Asymptomatic, Brain Ischemia, Cohort Studies, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Modified Rankin Scale, Internal medicine, Humans, Medicine, asymptomatic, Registries, 030212 general & internal medicine, Stroke, Thrombectomy, Intracerebral hemorrhage, business.industry, Endovascular Procedures, Odds ratio, medicine.disease, intracerebral hemorrhage, stroke, Confidence interval, 3. Good health, Treatment Outcome, Neurology, Cardiology, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Neurology (clinical), prognosis, medicine.symptom, business, Intracranial Hemorrhages, 030217 neurology & neurosurgery, Cohort study
Abstract

International audience; Background and purpose: Asymptomatic intracranial hemorrhage (aICH) is a common occurrence after endovascular treatment (EVT) for acute ischemic stroke (AIS). The aims of this study were to address its impact on 3-month functional outcome and to identify risk factors for aICH after EVT. Methods: Patients with AIS attributable to anterior circulation large vessel occlusion who underwent EVT were enrolled in a multicenter prospective registry. Based on imaging performed 22–36 h post-EVT, we included patients with no intracranial hemorrhage (ICH) or aICH. Poor outcome defined as a 3-month modified Rankin Scale (mRS) score 4–6 and overall 3-month mRS score distribution were compared according to presence/absence of aICH, and aICH subtype using logistic regression. We assessed the risk factors of aICH using a multivariate logistic regression model. Results: Of the 1526 patients included in the study, 653 (42.7%) had aICH. Patients with aICH had a higher rate of poor outcome: odds ratio (OR) 1.88 (95% confidence interval [CI] 1.44–2.44). Shift analysis of mRS score found a fully adjusted OR of 1.79 (95% CI 1.47–2.18). Hemorrhagic infarction (OR 1.63 [95% CI 1.22–2.18]) and parenchymal hematoma (OR 2.99 [95% CI 1.77–5.02]) were associated with higher risk of poor outcome. Male sex, diabetes, coronary artery disease, baseline National Institutes of Health Stroke Scale score and Alberta Stroke Program Early Computed Tomography Score, number of passes and onset to groin puncture time were independently associated with aICH. Conclusions: Patients with aICH, irrespective of the radiological pattern, have a worse functional outcome at 3 months compared with those without ICH after EVT for AIS. The number of EVT passes and the time from onset to groin puncture are factors that could be modified to reduce deleterious ICH.

Published
2021

13. Safety and Outcome of Carotid Dissection Stenting During the Treatment of Tandem Occlusions: A Pooled Analysis of TITAN and ETIS

Author

Marnat, Gaultier, Lapergue, Bertrand, Sibon, Igor, Gariel, Florent, Bourcier, Romain, Kyheng, Maeva, Labreuche, Julien, Dargazanli, Cyril, Consoli, Arturo, Blanc, Raphael, Piotin, Michel, Mazighi, Mikael, Richard, Sebastien, Gory, Benjamin, Redjem, Hocine, Escalard, Simon, Desilles, Jean-Philippe, Ciccio, Gabriele, Smajda, Stanislas, Fahed, Robert, Obadia, Mikael, Sabben, Candice, Corabianu, Ovide, De Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre-Yves, Taylor, Guillaume, Ben Maacha, Malek, Bourdain, Frédéric, Decroix, Jean-Pierre, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Coskun, Oguzhan, Di Maria, Federico, Rodesh, Georges, Leguen, Morgan, Tisserand, Marie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Nighoghossian, Norbert, Riva, Roberto, Eker, Omer, Turjman, Francis, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Claire Lukaszewicz, Anne, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne-Evelyne, Barreau, Xavier, Berge, Jérôme, Menegon, Patrice, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Rouanet, François, Tourdias, Thomas, Liegey, Jean-Sebastien, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre-Louis, Roy, Monica, Lenoble, Cédric, L’Allinec, Vincent, Girot, Jean-Baptiste, Desal, Hubert, Bracard, Serge, Anxionnat, René, Braun, Marc, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean-Christophe, Bonnerot, Mathieu, Riou-Comte, Nolwenn, Costalat, Vincent, Gascou, Grégory, Lefèvre, Pierre-Henri, Derraz, Imad, Riquelme, Carlos, Arquizan, Caroline, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, Cagnazzo, Federico, Anadani, Mohammad, Spiotta, Alejandro, Alawieh, Ali, Haussen, Diogo, Nogueira, Raul, Papanagiotou, Panagiotis, Siddiqui, Adnan, Dorn, Franziska, Cognard, Christophe, Ribo, Marc, Psychogios, Marios, Labeyrie, Marc Antoine, Biondi, Alessandra, Andrew Grossberg, Jonathan, Guenego, Adrien, Darcourt, Julien, Vukasinovic, Isabelle, Pomero, Elisa, Davies, Jason, Renieri, Leonardo, Hecker, Corentin, Muchada Muchada, Maria, Houdart, Emmanuel, Turner, Raymond, Turk, Aquilla, Chaudry, Imran, Lockau, Johanna, Kastrup, Andreas, Behme, Daniel, Shallwani, Hussain, Christopher, Maurer, Département de Neuro-Radiologie [Bordeaux] (DNR - Bordeaux), CHU Bordeaux [Bordeaux], Hôpital Foch [Suresnes], Service de neurologie [Bordeaux], CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Centre hospitalier universitaire de Nantes (CHU Nantes), Fondation Ophtalmologique Adolphe de Rothschild [Paris], Santé Publique : épidémiologie et qualité des soins (EA 2694), Université Lille 2 - Faculté de Médecine -Centre d'Etudes et de Recherche en Informatique Médicale [Lille] (CERIM), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département de Neuroradiologie[Montpellier], Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier]-Université de Montpellier (UM), Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de neurologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), and Université de Montpellier (UM)

Subjects
Male, MESH: Cerebral Hemorrhage, MESH: Cerebral Angiography, carotid dissection, Carotid Artery, Internal, Dissection, 030204 cardiovascular system & hematology, 0302 clinical medicine, MESH: Carotid Stenosis, MESH: Emergencies, Occlusion, Odds Ratio, Carotid Stenosis, Acute ischemic stroke, MESH: Treatment Outcome, MESH: Middle Aged, Cerebral infarction, Endovascular Procedures, MESH: Postoperative Hemorrhage, Middle Aged, cerebral infarction, 3. Good health, reperfusion, Dissection, Treatment Outcome, Pooled analysis, dissection, Female, Stents, Radiology, Internal carotid artery, Carotid dissection, Cardiology and Cardiovascular Medicine, Carotid Artery, Internal, MESH: Ischemic Stroke, Adult, medicine.medical_specialty, MESH: Carotid Artery, Internal, MESH: Endovascular Procedures, internal carotid artery, Postoperative Hemorrhage, MESH: Carotid Artery, Internal, Dissection, 03 medical and health sciences, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, medicine.artery, medicine, Humans, In patient, cardiovascular diseases, Mortality, Ischemic Stroke, Retrospective Studies, Advanced and Specialized Nursing, cerebral hemorrhage, MESH: Humans, MESH: Mortality, business.industry, MESH: Adult, MESH: Retrospective Studies, medicine.disease, MESH: Male, MESH: Odds Ratio, Cerebral Angiography, MESH: Stents, Neurology (clinical), Emergencies, business, MESH: Female, 030217 neurology & neurosurgery
Abstract

Background and Purpose: The efficacy of endovascular therapy in patients with acute ischemic stroke due to tandem occlusion is comparable to that for isolated intracranial occlusion in the anterior circulation. However, the optimal management of acute cervical internal carotid artery lesions is unknown, especially in the setting of carotid dissection, but emergency carotid artery stenting (CAS) is frequently considered. We investigated the safety and efficacy of emergency CAS for carotid dissection in patients with acute stroke with tandem occlusion in current clinical practice. Methods: We retrospectively analyzed a prospectively maintained database composed of 2 merged multicenter international observational real-world registries (Endovascular Treatment in Ischemic Stroke and Thrombectomy in Tandem Lesion). Data from endovascular therapy performed in the treatment of tandem occlusions related to acute cervical carotid dissection between January 2012 and January 2019 at 24 comprehensive stroke centers were analyzed. Results: The study assessed 136 patients with tandem occlusion due to dissection, including 65 (47.8%) treated with emergency CAS and 71 (52.2%) without. The overall rates of favorable outcome (90-day modified Rankin Scale score, 0–2) and successful reperfusion (modified Thrombolysis in Cerebral Infarction, 2b–3) were 58.0% (n=76 [95% CI, 49.6%–66.5%]) and 77.9% (n=106 [95% CI, 71.0%–85.0%]), respectively. In subgroup analyses, the rate of successful reperfusion (89.2% versus 67.6%; adjusted odds ratio, 2.24 [95% CI, 1.33–3.77]) was higher after CAS, whereas the 90-day favorable outcome (54.3% versus 61.4%; adjusted odds ratio, 0.84 [95% CI, 0.58–1.22]), symptomatic intracerebral hemorrhage (sICH; 10.8% versus 5.6%; adjusted odds ratio, 1.59 [95% CI, 0.79–3.17]), and 90-day mortality (8.0% versus 5.8%; adjusted odds ratio, 1.00 [95% CI, 0.48–2.09]) did not differ. In sensitivity analyses of patients with successful intracranial reperfusion, CAS was not associated with an improved clinical outcome. Conclusions: Emergency stenting of the dissected cervical carotid artery during endovascular therapy for tandem occlusions seems safe, whatever the quality of the intracranial reperfusion.

Published
2020

14. Mechanical Thrombectomy for Acute Ischemic Stroke Amid the COVID-19 Outbreak

Author

Kerleroux, Basile, Fabacher, Thibaut, Bricout, Nicolas, Moïse, Martin, Testud, Benoit, Vingadassalom, Sivadji, Ifergan, Héloïse, Janot, Kévin, Consoli, Arturo, Ben Hassen, Wagih, Shotar, Eimad, Ognard, Julien, Charbonnier, Guillaume, L’Allinec, Vincent, Guédon, Alexis, Bolognini, Federico, Marnat, Gaultier, Forestier, Géraud, Rouchaud, Aymeric, Pop, Raoul, Raynaud, Nicolas, Zhu, François, Cortese, Jonathan, Chalumeau, Vanessa, Berge, Jérome, Escalard, Simon, Boulouis, Grégoire, Chivot, Cyril, Hanafi, Riyad, Pasco, Anne, Girot, Jean-Baptiste, Biondi, Alessandra, Di Caterino, Fortunato, Primikiris, Panagiotis, Vitale, Giovanni, Bonnet, Louise, Gariel, Florent, Barreau, Xavier, Debruxelles, Sabrina, Lucas, Ludovic, Menegon, Patrice, Olindo, Stéphane, Poli, Mathilde, Renou, Pauline, Sagnier, Sharmila, Sibon, Igor, Veunac, Louis, Gentric, Jean-Christophe, Barbier, Charlotte, Boulanger, Marion, Cogez, Julien, Guettier, Sophie, Schneckenburger, Romain, Touze, Emmanuel, Delaitre, Mariette, Lebendinsky, Pablo, Musacchio, Mariano, Ricolfi, Frédéric, Thouant, Pierre, Caparros, François, Casolla, Barbara, Della Schiava, Lucie, Dequatre, Nelly, Henon, Hilde, Pasi, Marco, Kazemi, Apolline, Bala, Fouzi, Estrade, Laurent, Mounayer, Charbel, Saleme, Susanna, Macian-Montoro, Francisco, Eker, Omer, Cotton, François, Blanc-Lasserre, Karine, Cakmak, Serkan, Cho, Tae-Hee, Derex, Laurent, Lukaszewicz, Anne-Claire, Mechtouff, Laura, Nighoghossian, Norbert, Philippeau, Frédéric, Riva, Roberto, Turjman, Francis, Vallet, Anne-Evelyne, Carle, Xavier, Dory-Lautrec, Philippe, Reyre, Anthony, Hak, Jean-François, Brunel, Hervé, Benali, Amel, Collemiche, François-Louis, Dargazanli, Cyril, Cagnazzo, Frederico, Derraz, Imad, Arquizan, Caroline, Corti, Lucas, Costalat, Vincent, Gaillard, Nicolas, Gascou, Grégory, Lefèvre, Pierre-Henri, Mourand, Isabelle, Riquelme, Carlos, Derelle, Anne Laure, Gory, Benjamin, Liao, Liang, Tonnelet, Romain, Anxionnat, René, Bonnerot, Mathieu, Bracard, Serge, Braun, Marc, Humbertjean, Lisa, Lacour, Jean-Christophe, Mione, Gioia, Planel, Sophie, Richard, Sébastien, Riou-Comte, Nolwenn, Schmitt, Emmanuelle, Bourcier, Romain, Detraz, Lili, Desal, Hubert, Alexandre, Pierre-Louis, Daumas-Duport, Benjamin, Lenoble, Cédric, Roy, Monica, Coskun, Oghuzan, Di Maria, Frederico, Lapergue, Bertrand, Rodesch, Georges, Wang, Adrien, Weisenburger-Lile, David, Zimatore, Sergio, Ajili, Nadia, Buard, Géraldine, Evrard, Serge, Gorza, Lucas, Gratieux, Julie, Leguen, Morgan, Marinier, Sylvie, Pico, Fernando, Poll, Roxanna, Rakotoharinandrasana, Haja, Tassan, Philippe, Tchikviladze, Maya, Delvoye, François, Hebert, Solène, Blanc, Raphaël, Ciccio, Gabriele, Desilles, Jean-Philippe, Maier, Benjamin, Mazighi, Mikael, Piotin, Michel, Redjem, Hocine, Smajda, Stanislas, Ben Maacha, Malek, Corabianu, Ovide, De Broucker, Thomas, Ille, Olivier, Manchon, Eric, Obadia, Michael, Obadia, Mickael, Raynouard, Igor, Peres, Roxanne, Sabben, Candice, Smadja, Didier, Taylor, Guillaume, Thion, Laurie-Anne, Lecler, Augustin, Denier, Christian, Caroff, Jildaz, Chassin, Olivier, Spelle, Laurent, Venditti, Laura, Aymard, Armand, Betty, Jean, Civelli, Vittorio, Eliezer, Michael, Fantoni, Matteo, Houdart, Emmanuel, Labeyrie, Marc-Antoine, Saint Maurice, Jean-Pierre, Kalsoum, Erwah, Pacini, Aurelien, Ramadane, Chawkat, Tuilier, Titien, Villain, Adrien, Clarencon, Frédéric, Degos, Vincent, Elhfnawy, Ahmed, Elhorany, Mahmoud, Lenck, Stéphanie, Premat, Kevin, Sourour, Nader-Antoine, Alamowitch, Sonia, Baronnet, Flore, Crozier, Sophie, Deltour, Sandrine, Leger, Anne, Rosso, Charlotte, Pyatigorskaya, Nadya, Rodriguez Regent, Christine, Trystram, Denis, Naggara, Olivier, Seners, Pierre, Turc, Guillaume, Edjlali, Myriam, Agbonon, Rémi, Alotaibi, Mohammed, Sonchet, Antoine, Oppenheim, Catherine, Meder, Jean François, Benzakoun, Joseph, Legrand, Laurence, Fauché, Cédric, Velasco, Stéphane, Manceau, Pierre François, Moulin, Sebastien Solène Soize, Ferré, Jean-Christophe, Paya, Christophe, Eugene, François, Gauvrit, Jean-Yves, Langnier-Lemercier, Sophie, Lassale, Maria, Raoult, helene, Ronziere, Thomas, Tracol, Clément, Vannier, Stéphane, Burel, Julien, Le Moal, Julien, Papagiannaki, Chrysanthi, Aggour, Mohamed, Sachet, Marina, Boutet, Claire, Beaujeux, Remy, Hasiu, Anca, Manisor, Monica, Mihoc, Dan, Kremer, Stéphane, Arteaga, Charles, Gazzola, Sébastien, Darcourt, Jean, Cognard, Christophe, Bonneville, Fabrice, Christine Januel, Anne, Olivot, Jean-Marc, Raposo, Nicolas, Viguier, Alain, Bibi, Richard, Boustia, Fakhreddine, Herbreteau, Denis, Maldonado, Igor, Narata, Ana-Paula, Service de neuroradiologie [Paris], Hôpital Sainte-Anne, CHU Strasbourg, Service de neuroradiologie [Lille], Hôpital Roger Salengro [Lille]-Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de neuroradiologie diagnostique et interventionnelle, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Service de neuroradiologie [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Service Neuroradiologie diagnostique et interventionnelle [Hôpital Foch], Hôpital Foch [Suresnes], Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Service de Neuroradiologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Neuroradiologie [Brest], Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Neurologie [Hôpitaux Civils de Colmar], Hôpitaux Civils Colmar, Département de Neuro-Radiologie [Bordeaux] (DNR - Bordeaux), CHU Bordeaux [Bordeaux], Service de Neuroradiologie interventionnelle [CHU Limoges], CHU Limoges, Département de Neuroradiologie [Strasbourg], Les Hôpitaux Universitaires de Strasbourg (HUS), Service de neurologie [Poitiers], Centre hospitalier universitaire de Poitiers (CHU Poitiers), Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de Neuroradiologie [CHU de Bicêtre], Hôpital Rothschild [AP-HP], Faculté de Médecine [Nancy], Université de Lorraine (UL), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Rothschild [AP-HP], Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Service de neuroradiologie diagnostique et fonctionnelle [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)

Subjects
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

International audience; Background and Purpose: The efficiency of prehospital care chain response and the adequacy of hospital resources are challenged amid the coronavirus disease 2019 (COVID-19) outbreak, with suspected consequences for patients with ischemic stroke eligible for mechanical thrombectomy (MT). Methods: We conducted a prospective national-level data collection of patients treated with MT, ranging 45 days across epidemic containment measures instatement, and of patients treated during the same calendar period in 2019. The primary end point was the variation of patients receiving MT during the epidemic period. Secondary end points included care delays between onset, imaging, and groin puncture. To analyze the primary end point, we used a Poisson regression model. We then analyzed the correlation between the number of MTs and the number of COVID-19 cases hospitalizations, using the Pearson correlation coefficient (compared with the null value). Results: A total of 1513 patients were included at 32 centers, in all French administrative regions. There was a 21% significant decrease (0.79; [95%CI, 0.76–0.82]; P

Published
2020

15. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data

Author

Thomalla, Götz, primary, Boutitie, Florent, additional, Ma, Henry, additional, Koga, Masatoshi, additional, Ringleb, Peter, additional, Schwamm, Lee H, additional, Wu, Ona, additional, Bendszus, Martin, additional, Bladin, Christopher F, additional, Campbell, Bruce C V, additional, Cheng, Bastian, additional, Churilov, Leonid, additional, Ebinger, Martin, additional, Endres, Matthias, additional, Fiebach, Jochen B, additional, Fukuda-Doi, Mayumi, additional, Inoue, Manabu, additional, Kleinig, Timothy J, additional, Latour, Lawrence L, additional, Lemmens, Robin, additional, Levi, Christopher R, additional, Leys, Didier, additional, Miwa, Kaori, additional, Molina, Carlos A, additional, Muir, Keith W, additional, Nighoghossian, Norbert, additional, Parsons, Mark W, additional, Pedraza, Salvador, additional, Schellinger, Peter D, additional, Schwab, Stefan, additional, Simonsen, Claus Z, additional, Song, Shlee S, additional, Thijs, Vincent, additional, Toni, Danilo, additional, Hsu, Chung Y, additional, Wahlgren, Nils, additional, Yamamoto, Haruko, additional, Yassi, Nawaf, additional, Yoshimura, Sohei, additional, Warach, Steven, additional, Hacke, Werner, additional, Toyoda, Kazunori, additional, Donnan, Geoffrey A, additional, Davis, Stephen M, additional, Gerloff, Christian, additional, Acosta, Boris Raul, additional, Aegidius, Karen, additional, Albiker, Christian, additional, Alegiani, Anna, additional, Almendrote, Miriam, additional, Alonso, Angelika, additional, Althaus, Katharina, additional, Amarenco, Pierre, additional, Amiri, Hemasse, additional, Anders, Bettina, additional, Aniculaesei, Adriana, additional, Appleton, Jason, additional, Arenillas, Juan, additional, Back, Christina, additional, Bähr, Christian, additional, Bardutzky, Jürgen, additional, Baronnet-Chauvet, Flore, additional, Bathe-Peters, Rouven, additional, Bayer-Karpinska, Anna, additional, Becerra, Juan L., additional, Beck, Christoph, additional, Belchí Guillamon, Olga, additional, Benoit, Amandine, additional, Berhoune, Nadia, additional, Bindila, Daniela, additional, Birchenall, Julia, additional, Blanc-Lasserre, Karine, additional, Blanco Gonzales, Miguel, additional, Bobinger, Tobias, additional, Bodechtel, Ulf, additional, Bodiguel, Eric, additional, Bojaryn, Urszula, additional, Bonnet, Louise, additional, Bouamra, Benjamin, additional, Bourgeois, Paul, additional, Breuer, Lorenz, additional, Breynaert, Ludovic, additional, Broughton, David, additional, Brouns, Raf, additional, Brugirard, Sébastian, additional, Bruneel, Bart, additional, Buggle, Florian, additional, Cakmak, Serkan, additional, Calleja, Ana, additional, Calvet, David, additional, Carrera, David, additional, Chen, Hsin-Chieh, additional, Cheripelli, Bharath, additional, Cho, Tae-Hee, additional, Choe, Chi-un, additional, Choy, Lillian, additional, Christensen, Hanne, additional, Ciatipis, Mareva, additional, Cloud, Geoffrey, additional, Cogez, Julien, additional, Cortijo, Elisa, additional, Crozier, Sophie, additional, Damgaard, Dorte, additional, Dani, Krishna, additional, De Coene, Beatrijs, additional, De Hollander, Isabel, additional, De Keyser, Jacques, additional, De Klippel, Nina, additional, De Maeseneire, Charlotte, additional, De Smedt, Ann, additional, del Mar Castellanos Rodrigo, Maria, additional, Deltour, Sandrine, additional, Demeestere, Jelle, additional, Derex, Laurent, additional, Desfontaines, Philippe, additional, Dittrich, Ralf, additional, Dixit, Anand, additional, Dobbels, Laurens, additional, Domigo, Valérie, additional, Dorado, Laura, additional, Druart, Charlotte, additional, Dupont, Kristina Hougaard, additional, Dusart, Anne, additional, Dziewas, Rainer, additional, Ebner, Matthias, additional, Edjali-Goujon, Myriam, additional, Eisele, Philipp, additional, El Tawil, Salwa, additional, Elhfnawy, Ahmed, additional, Etexberria, Ana, additional, Evans, Nicholas, additional, Fandler, Simon, additional, Fazekas, Franz, additional, Felix, Sandra, additional, Fiebach, Jochen B., additional, Fiehler, Jens, additional, Filipov, Alexandra, additional, Filipski, Katharina, additional, Fleischmann, Robert, additional, Foerch, Christian, additional, Ford, Ian, additional, Gaenslen, Alexandra, additional, Galinovic, Ivana, additional, Gancedo, Elena Meseguer, additional, Ganeshan, Ramanan, additional, García Esperón, Carlos, additional, Garrido, Alicia, additional, Gattringer, Thomas, additional, Geraghty, Olivia, additional, Geran, Rohat, additional, Gerner, Stefan, additional, Godon-Hardy, Sylvie, additional, Göhler, Jos, additional, Golsari, Amir, additional, Gomis, Meritxell, additional, Gorriz, David, additional, Gramse, Verena, additional, Grau, Laia, additional, Griebe, Martin, additional, Guerrero, Cristina, additional, Guerzoglu, Damla, additional, Guettier, Sophie, additional, Guiraud, Vincent, additional, Gumbinger, Christoph, additional, Gunreben, Ignaz, additional, Haertig, Florian, additional, Hametner, Christian, additional, Hanseeuw, Bernard, additional, Hansen, Andreas, additional, Hansen, Jakob, additional, Harbo, Thomas, additional, Harloff, Andreas, additional, Harmel, Peter, additional, Häusler, Karl Georg, additional, Heinen, Florian, additional, Held, Valentin, additional, Hellwig, Simon, additional, Hemelsoet, Dimitri, additional, Hennerici, Michael, additional, Herm, Juliane, additional, Hermans, Sylvia, additional, Hernández, María, additional, Hervas Vicente, Jose, additional, Hjort, Niels, additional, Hobeanu, Cristina, additional, Hobohm, Carsten, additional, Höfner, Elmar, additional, Hohenbichler, Katharina, additional, Hommel, Marc, additional, Hoppe, Julia, additional, Hornberger, Eva, additional, Hoyer, Carolin, additional, Huang, Xuya, additional, Ipsen, Nils, additional, Isern, Irina, additional, Ispierto, Lourdes, additional, Iversen, Helle, additional, Jeppesen, Lise, additional, Jimenez, Marta, additional, Jungehülsing, Jan, additional, Jüttler, Eric, additional, Kalladka, Dheeraj, additional, Kallmünzer, Bernd, additional, Kar, Arindam, additional, Kellert, Lars, additional, Kemmling, André, additional, Kessler, Tobias, additional, Khan, Usman, additional, Klein, Matthias, additional, Kleinschnitz, Christoph, additional, Klockziem, Matti, additional, Knops, Michael, additional, Koehler, Luzie, additional, Koehrmann, Martin, additional, Kohlfürst, Heinz, additional, Kollmar, Rainer, additional, Kraft, Peter, additional, Krause, Thomas, additional, Kristensen, Bo, additional, Kröber, Jan M., additional, Kurka, Natalia, additional, Ladoux, Alexandre, additional, Laloux, Patrice, additional, Lamy, Catherine, additional, Landrault, Emmanuelle, additional, Lauer, Arne, additional, Lebely, Claire, additional, Leempoel, Jonathan, additional, Lees, Kennedy, additional, Leger, Anne, additional, Legrand, Laurence, additional, Li, Lin, additional, Löbbe, Anna-Mareike, additional, London, Frederic, additional, Lopez-cancio, Elena, additional, Lorenz, Matthias, additional, Louw, Stephen, additional, Lovelock, Caroline, additional, Lozano Sánchez, Manuel, additional, Lucente, Giuseppe, additional, Lückl, Janos, additional, Luna, Alain, additional, Macha, Kosmas, additional, Machet, Alexandre, additional, Mackenrodt, Daniel, additional, Madzar, Dominik, additional, Majoie, Charles, additional, Männer, Anika, additional, Maqueda, Vicky, additional, Marstrand, Jacob, additional, Martinez, Alicia, additional, Marzina, Annika, additional, Mechthouff, Laura, additional, Meden, Per, additional, Meersman, Guy, additional, Meier, Julia, additional, Mellerio, Charles, additional, Menn, Oliver, additional, Meyer, Nadja, additional, Michalski, Dominik, additional, Michels, Peter, additional, Michelsen, Lene, additional, Millán Torne, Monica, additional, Minnerup, Jens, additional, Modrau, Boris, additional, Moeller, Sebastian, additional, Møller, Anette, additional, Morel, Nathalie, additional, Moreton, Fiona, additional, Morin, Ludovic, additional, Moulin, Thierry, additional, Moynihan, Barry, additional, Mueller, Anne K., additional, Muir, Keith W., additional, Mulero, Patricia, additional, Mundiyanapurath, Sibu, additional, Mutzenbach, Johannes, additional, Nagel, Simon, additional, Naggara, Oliver, additional, Nallasivan, Arumugam, additional, Navalpotro, Irene, additional, Nave, Alexander H., additional, Nederkoorn, Paul, additional, Neeb, Lars, additional, Neugebauer, Hermann, additional, Neumann-Haefelin, Tobias, additional, Oberndorfer, Stefan, additional, Opherk, Christian, additional, Oppel, Lorenz, additional, Oppenheim, Catherine, additional, Orthgieß, Johannes, additional, Ostergaard, Leif, additional, Paindeville, Perrine, additional, Palomeras, Ernest, additional, Panitz, Verena, additional, Patel, Bhavni, additional, Peeters, Andre, additional, Peeters, Dirk, additional, Pellisé, Anna, additional, Pelz, Johann, additional, Pereira, Anthony, additional, Pérez de la Ossa, Natalia, additional, Perry, Richard, additional, Petraza, Salvador, additional, Peysson, Stéphane, additional, Pfeilschifter, Waltraud, additional, Pichler, Alexander, additional, Pierskalla, Alexandra, additional, Pledl, Hans-Werner, additional, Poli, Sven, additional, Pomrehn, Katrin, additional, Poulsen, Marika, additional, Prats, Luis, additional, Presas, Silvia, additional, Prohaska, Elisabeth, additional, Puetz, Volker, additional, Puig, Josep, additional, Puig Alcántara, Josep, additional, Purrucker, Jan, additional, Quenardelle, Veronique, additional, Ramachandran, Sankaranarayanan, additional, Raphaelle, Soulliard, additional, Raposo, Nicolas, additional, Reiff, Tilman, additional, Remmers, Michel, additional, Renou, Pauline, additional, Ribitsch, Martin, additional, Richter, Hardy, additional, Ritter, Martin, additional, Ritzenthaler, Thomas, additional, Rodier, Gilles, additional, Rodriguez-Regent, Christine, additional, Rodríguez-Yáñez, Manuel, additional, Roennefarth, Maria, additional, Roffe, Christine, additional, Rosenbaum, Sverre, additional, Rosso, Charlotte, additional, Röther, Joachim, additional, Rozanski, Michal, additional, Ruiz de Morales, Noelia, additional, Russo, Francesca, additional, Rutgers, Matthieu, additional, Sagnier, Sharmilla, additional, Samson, Yves, additional, Sánchez, Josep, additional, Sauer, Tamara, additional, Schäfer, Jan H., additional, Schieber, Simon, additional, Schill, Josef, additional, Schlak, Dennis, additional, Schlemm, Ludwig, additional, Schmidt, Sein, additional, Schonewille, Wouter, additional, Schröder, Julian, additional, Schulz, Andreas, additional, Schurig, Johannes, additional, Schwarting, Sönke, additional, Schwarz, Alexander, additional, Schwarzbach, Christopher, additional, Seidel, Matthias, additional, Seiler, Alexander, additional, Sembill, Jochen, additional, Serena Leal, Joaquin, additional, Shetty, Ashit, additional, Sibon, Igor, additional, Simonsen, Claus Z., additional, Singer, Oliver, additional, Sivagnanaratham, Aravinth, additional, Smets, Ide, additional, Smith, Craig, additional, Soors, Peter, additional, Sprigg, Nikola, additional, Spruegel, Maximilian, additional, Stark, David, additional, Steinert, Susanne, additional, Stösser, Sebastian, additional, Stuermlinger, Markus, additional, Swinnen, Bart, additional, Tamazyan, Ruben, additional, Tembl, Jose, additional, Terceno Izaga, Mikel, additional, Thomalla, Götz, additional, Touze, Emmanuel, additional, Truelsen, Thomas, additional, Turc, Guillaume, additional, Turine, Gaetane, additional, Tütüncü, Serdar, additional, Tyrell, Pippa, additional, Ustrell, Xavier, additional, Vadot, Wilfried, additional, Vallet, Anne-Evelyne, additional, Vallet, Pauline, additional, van den Berg, Lucie, additional, van den Berg, Sophie, additional, van Eendenburg, Cecile, additional, Van Hooff, Robbert-Jan, additional, van Sloten, Isabelle, additional, Vanacker, Peter, additional, Vancaester, Evelien, additional, Vanderdonckt, Patrick, additional, Vandermeeren, Yves, additional, Vanhee, Frederik, additional, Veltkamp, Roland, additional, Vestergaard, Karsten, additional, Viguier, Alain, additional, Vilas, Dolores, additional, Villringer, Kersten, additional, Voget, Dieke, additional, von Schrader, Jörg, additional, von Weitzel, Paul, additional, Warburton, Elisabeth, additional, Weber, Claudia, additional, Weber, Jörg, additional, Wegscheider, Karl, additional, Wegscheider, Mirko, additional, Weimar, Christian, additional, Weinstich, Karin, additional, Weise, Christopher, additional, Weise, Gesa, additional, Willems, Chris, additional, Winder, Klemens, additional, Wittayer, Matthias, additional, Wolf, Marc, additional, Wolf, Martin, additional, Wolff, Valerie, additional, Wollboldt, Christian, additional, Wollenweber, Frank, additional, Wouters, Anke, additional, Yalo, Bertrand, additional, Yger, Marion, additional, Younan, Nadia, additional, Yperzeele, Laetita, additional, Zegarac, Vesna, additional, Zeiner, Pia, additional, Ziemann, Ulf, additional, Zonneveld, Thomas, additional, Zuber, Mathieu, additional, Akutsu, Tsugio, additional, Aoki, Junya, additional, Arakawa, Shuji, additional, Doijiri, Ryosuke, additional, Egashira, Yusuke, additional, Enomoto, Yukiko, additional, Furui, Eisuke, additional, Furuta, Konosuke, additional, Gotoh, Seiji, additional, Hamasaki, Toshimitsu, additional, Hasegawa, Yasuhiro, additional, Hirano, Teryuki, additional, Homma, Kazunari, additional, Ichijyo, Masahiko, additional, Ide, Toshihiro, additional, Igarashi, Shuichi, additional, Iguchi, Yasuyuki, additional, Ihara, Masafumi, additional, Ikenouchi, Hajime, additional, Inoue, Tsuyoshi, additional, Itabashi, Ryo, additional, Ito, Yasuhiro, additional, Iwama, Toru, additional, Kamiyama, Kenji, additional, Kamiyoshi, Shoko, additional, Kanai, Haruka, additional, Kanematsu, Yasuhisa, additional, Kanzawa, Takao, additional, Kimura, Kazumi, additional, Kitayama, Jiro, additional, Kitazono, Takanari, additional, Kondo, Rei, additional, Kudo, Kohsuke, additional, Kusumi, Masayoshi, additional, Kuwahara, Ken, additional, Matsumoto, Shoji, additional, Matsuoka, Hideki, additional, Mihara, Ban, additional, Minematsu, Kazuo, additional, Miura, Ken, additional, Morita, Naomi, additional, Mouri, Wataru, additional, Murata, Kayo, additional, Nagakane, Yoshinari, additional, Nakase, Taizen, additional, Ohara, Hiromi, additional, Ohara, Nobuyuki, additional, Ohnishi, Hideyuki, additional, Ohta, Hajime, additional, Ohtaki, Masafumi, additional, Ohtani, Ryo, additional, Ohtsuki, Toshiho, additional, Ohyama, Hideo, additional, Okada, Takashi, additional, Okada, Yasushi, additional, Osaki, Masato, additional, Sakai, Nobuyuki, additional, Sanbongi, Yoshiki, additional, Sasaki, Naoshi, additional, Sasaki, Makoto, additional, Sato, Shoichiro, additional, Seki, Kenta, additional, Shimizu, Wataru, additional, Shiokawa, Yoshiaki, additional, Sozu, Takashi, additional, Suzuki, Junichiro, additional, Suzuki, Rieko, additional, Takagi, Yasushi, additional, Takizawa, Shunya, additional, Tanahashi, Norio, additional, Tanaka, Eijiro, additional, Tanaka, Ryota, additional, Tateishi, Yohei, additional, Terada, Tomoaki, additional, Terasaki, Tadashi, additional, Todo, Kenichi, additional, Tokunaga, Azusa, additional, Tsujino, Akira, additional, Ueda, Toshihiro, additional, Uesaka, Yoshikazu, additional, Uotani, Mihoko, additional, Urabe, Takao, additional, Watanabe, Masao, additional, Yagita, Yoshiki, additional, Yakushiji, Yusuke, additional, Yasui, Keizo, additional, Yonehara, Toshiro, additional, Yoshimura, Shinichi, additional, Aarnio, K., additional, Alemseged, F., additional, Anderson, C., additional, Ang, T., additional, Archer, M.L., additional, Attia, J., additional, Bailey, P., additional, Balabanski, A., additional, Barber, A., additional, Barber, P.A., additional, Bernhardt, J., additional, Bivard, A., additional, Blacker, D., additional, Bladin, C.F., additional, Brodtmann, A., additional, Cadilhac, D., additional, Campbell, B.C.V., additional, Carey, L., additional, Celestino, S., additional, Chan, L., additional, Chang, W.H., additional, ChangI, A., additional, Chen, C.H., additional, Chen, C.-I., additional, Chen, H.F., additional, Chen, T.C., additional, Chen, W.H., additional, Chen, Y.Y., additional, Cheng, C.A., additional, Cheong, E., additional, Chiou, Y.W., additional, Choi, P.M., additional, Chu, H.J., additional, Chuang, C.S., additional, Chung, T.C., additional, Churilov, L., additional, Clissold, B., additional, Connelly, A., additional, Coote, S., additional, Coulton, B., additional, Cowley, E., additional, Cranefield, J., additional, Curtze, S., additional, D'Este, C., additional, Davis, S.M., additional, Day, S., additional, Desmond, P.M., additional, Dewey, H.M., additional, Ding, C., additional, Donnan, G.A., additional, Drew, R., additional, Eirola, S., additional, Field, D., additional, Frost, T., additional, Garcia-Esperon, C., additional, George, K., additional, Gerraty, R., additional, Grimley, R., additional, Guo, Y.C., additional, Hankey, G., additional, Harvey, J., additional, Ho, S.C., additional, Hogan, K., additional, Howells, D., additional, Hsiao, P.M., additional, Hsu, C.H., additional, Hsu, C.T., additional, Hsu, C.-S., additional, Hsu, J.P., additional, Hsu, Y.D., additional, Hsu, Y.T., additional, Hu, C.J., additional, Huang, C.C., additional, Huang, H.Y., additional, Huang, M.Y., additional, Huang, S.C., additional, Huang, W.S., additional, Jackson, D., additional, Jeng, J.S., additional, Jiang, S.K., additional, Kaauwai, L., additional, Kasari, O., additional, King, J., additional, Kleinig, T.J., additional, Koivu, M., additional, Kolbe, J., additional, Krause, M., additional, Kuan, C.W., additional, Kung, W.L., additional, Kyndt, C., additional, Lau, C.L., additional, Lee, A., additional, Lee, C.Y., additional, Lee, J.T., additional, Lee, Y., additional, Lee, Y.C., additional, Levi, C., additional, Levi, C.R., additional, Lien, L.M., additional, Lim, J.C., additional, Lin, C.C., additional, Lin, C.H., additional, Lin, C.M., additional, Lin, D., additional, Liu, C.H., additional, Liu, J., additional, Lo, Y.C., additional, Loh, P.S., additional, Low, E., additional, Lu, C.H., additional, Lu, C.J., additional, Lu, M.K., additional, Ly, J., additional, Ma, H., additional, Macaulay, L., additional, Macdonnell, R., additional, Mackey, E., additional, Macleod, M., additional, Mahadevan, J., additional, Maxwell, V., additional, McCoy, R., additional, McDonald, A., additional, McModie, S., additional, Meretoja, A., additional, Mishra, S., additional, Mitchell, P.J., additional, Miteff, F., additional, Moore, A., additional, Muller, C., additional, Ng, F., additional, Ng, F.C., additional, Ng, J-L., additional, O'Brian, W., additional, O'Collins, V., additional, Oxley, T.J., additional, Parsons, M.W., additional, Patel, S., additional, Peng, G.S., additional, Pesavento, L., additional, Phan, T., additional, Rodrigues, E., additional, Ross, Z., additional, Sabet, A., additional, Sallaberger, M., additional, Salvaris, P., additional, Shah, D., additional, Sharma, G., additional, Sibolt, G., additional, Simpson, M., additional, Singhal, S., additional, Snow, B., additional, Spratt, N., additional, Stark, R., additional, Sturm, J., additional, Sun, M.C., additional, Sun, Y., additional, Sung, P.S., additional, Sung, Y.F., additional, Suzuki, M., additional, Tan, M., additional, Tang, S.C., additional, Tatlisumak, T., additional, Thijs, V., additional, Tiainen, M., additional, Tsai, C.H., additional, Tsai, C.K., additional, Tsai, C.L., additional, Tsai, H.T., additional, Tsai, L.K., additional, Tseng, C.H., additional, Tseng, L.T., additional, Tsoleridis, J., additional, Tu, H., additional, Tu, H.T-H., additional, Vallat, W., additional, Virta, J., additional, Wang, W.C., additional, Wang, Y.T., additional, Waters, M., additional, Weir, L., additional, Wijeratne, T., additional, Williams, C., additional, Wilson, W., additional, Wong, A.A., additional, Wong, K., additional, Wu, T.Y., additional, Wu, Y.H., additional, Yan, B., additional, Yang, F.C., additional, Yang, Y.W., additional, Yassi, N., additional, Yeh, H.L., additional, Yeh, J.H., additional, Yeh, S.J., additional, Yen, C.H., additional, Young, D., additional, Ysai, C.L., additional, Zhang, W.W., additional, Zhao, H., additional, Zhao, L., additional, Althaus-Knaurer, Katharina, additional, Berrouschot, Jörg, additional, Bluhmki, Erich, additional, Bovi, Paolo, additional, Chatellier, Gilles, additional, Cove, Lynda, additional, Davis, Stephen, additional, Dixit, A., additional, Donnan, Geoffrey, additional, Ehrenkrona, Christina, additional, Eschenfelder, Christoph, additional, Fatar, Marc, additional, Francisco Arenillas, Juan, additional, Gruber, Franz, additional, Kala, Lalit, additional, Kapeller, Peter, additional, Kaste, Markku, additional, Kessler, Christof, additional, Köhrmann, Martin, additional, Laage, Rico, additional, Lees, Kennedy R., additional, Luna Rodriguez, Alain, additional, Mas, Jean-Louis, additional, Mikulik, Robert, additional, Molina, Carlos, additional, Muddegowda, Girish, additional, Muir, Keith, additional, Niederkorn, Kurt, additional, Nuñez, Xavier, additional, Schellinger, Peter, additional, Serena, Joaquin, additional, Sobesky, Jan, additional, Steiner, Thorsten, additional, Svenson, Ann-Sofie, additional, von Kummer, Rüdiger, additional, Wardlaw, Joanna, additional, Betensky, Rebecca A., additional, Boulouis, Gregoire, additional, Carandang, Raphael A., additional, Copen, William A., additional, Cougo, Pedro, additional, Cutting, Shawna, additional, Drake, Kendra, additional, Ford, Andria L., additional, Hallenbeck, John, additional, Harris, Gordon J., additional, Hoesch, Robert, additional, Hsia, Amie, additional, Kase, Carlos, additional, Latour, Lawrence, additional, Lev, Michael H., additional, Muzikansky, Alona, additional, Nagaraja, Nandakumar, additional, Schwamm, Lee H., additional, Searls, Eric, additional, Song, Shlee S., additional, Starkman, Sidney, additional, Yoo, Albert J., additional, and Zand, Ramin, additional

Published
2020
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16. Temporal trends in reperfusion therapy for patients with acute ischemic stroke.

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El Khoury, Carlos, Aboa-Eboule, Corine, Fraticelli, Laurie, Claustre, Clément, Bischoff, Magali, Blanc-Lasserre, Karine, Buisson, Marielle, Cakmak, Serkan, Tee-hi Cho, Ferroud-Plattet, Bruno, Guerrier, Olivier, Philippeau, Frédéric, Serre, Patrice, Mechtouff, Laura, Nighoghossian, Norbert, Ruzteroltz, Thierry, Vallet, Anne-Evelyne, Ong, Elodie, and Derex, Laurent

Published
2022
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18. Predictors of Unexplained Early Neurological Deterioration After Endovascular Treatment for Acute Ischemic Stroke

Author

Girot, Jean-Baptiste, primary, Richard, Sébastien, additional, Gariel, Florent, additional, Sibon, Igor, additional, Labreuche, Julien, additional, Kyheng, Maéva, additional, Gory, Benjamin, additional, Dargazanli, Cyril, additional, Maier, Benjamin, additional, Consoli, Arturo, additional, Daumas-Duport, Benjamin, additional, Lapergue, Bertrand, additional, Bourcier, Romain, additional, Piotin, Michel, additional, Blanc, Raphael, additional, Redjem, Hocine, additional, Escalard, Simon, additional, Desilles, Jean-Philippe, additional, Ciccio, Gabriele, additional, Smajda, Stanislas, additional, Mazighi, Mikael, additional, Obadia, Mikael, additional, Sabben, Candice, additional, Peres, Roxanne, additional, Corabianu, Ovide, additional, de Broucker, Thomas, additional, Smadja, Didier, additional, Alamowitch, Sonia, additional, Ille, Olivier, additional, Manchon, Eric, additional, Garcia, Pierre-Yves, additional, Taylor, Guillaume, additional, Ben Maacha, Malek, additional, Wang, Adrien, additional, Evrard, Serge, additional, Tchikviladze, Maya, additional, Ajili, Nadia, additional, Weisenburger, David, additional, Gorza, Lucas, additional, Buard, Géraldine, additional, Coskun, Oguzhan, additional, Di Maria, Federico, additional, Rodesh, Georges, additional, Zimatore, Sergio, additional, Leguen, Morgan, additional, Gratieux, Julie, additional, Pico, Fernando, additional, Rakotoharinandrasana, Haja, additional, Tassan, Philippe, additional, Poll, Roxanna, additional, Marinier, Sylvie, additional, Nighoghossian, Norbert, additional, Riva, Roberto, additional, Eker, Omer, additional, Turjman, Francis, additional, Derex, Laurent, additional, Cho, Tae-Hee, additional, Mechtouff, Laura, additional, Claire Lukaszewicz, Anne, additional, Philippeau, Frédéric, additional, Cakmak, Serkan, additional, Blanc-Lasserre, Karine, additional, Vallet, Anne-Evelyne, additional, Marnat, Gaultier, additional, Barreau, Xavier, additional, Berge, Jérôme, additional, Veunac, Louis, additional, Menegon, Patrice, additional, Lucas, Ludovic, additional, Olindo, Stéphane, additional, Renou, Pauline, additional, Sagnier, Sharmila, additional, Poli, Mathilde, additional, Debruxelles, Sabrina, additional, Tourdias et Jean-Sebastien Liegey, Thomas, additional, Detraz, Lili, additional, Alexandre, Pierre-Louis, additional, Roy, Monica, additional, Lenoble, Cédric, additional, L’allinec, Vincent, additional, Desal, Hubert, additional, Guillon, Benoît, additional, de Gaalon, Solène, additional, Preterre, Cécile, additional, Bracard, Serge, additional, Anxionnat, René, additional, Braun, Marc, additional, Derelle, Anne-Laure, additional, Tonnelet, Romain, additional, Liao, Liang, additional, Zhu, François, additional, Schmitt, Emmanuelle, additional, Planel, Sophie, additional, Humbertjean, Lisa, additional, Mione, Gioia, additional, Lacour, Jean-Christophe, additional, Bonnerot, Mathieu, additional, Riou-Comte, Nolwenn, additional, Macian-Montoro, Francisco, additional, Saleme, Suzanna, additional, Mounayer, Charbel, additional, Rouchaud, Aymeric, additional, Costalat, Vincent, additional, Arquizan, Caroline, additional, Gascou, Grégory, additional, Lefèvre, Pierre-Henri, additional, Derraz, Imad, additional, Riquelme, Carlos, additional, Gaillard, Nicolas, additional, Mourand, Isabelle, additional, Corti, Lucas, additional, Francois, Eugene, additional, Vannier, Stéphane, additional, Ferre, Jean-Christophe, additional, Raoult, Helene, additional, Ronziere, Thomas, additional, Lassale, Maria, additional, Paya, Christophe, additional, Gauvrit, Jean-Yves, additional, Tracol, Clément, additional, Langnier-Lemercier, Sophie, additional, Samson, Yves, additional, Rosso, Charlotte, additional, Leger, Anne, additional, Deltour, Sandrine, additional, Clarencon, Frederic, additional, Shotar, Eimad, additional, Spelle, Laurent, additional, Denier, Christian, additional, Chassin, Olivier, additional, Chalumeau, Vanessa, additional, Caroff, Jildaz, additional, Venditti, Laura, additional, Turc, Guillaume, additional, Naggara, Glivier, additional, Boulouis, Gregoire, additional, Ben Hassen, Waghih, additional, Seners, Pierre, additional, Viguier, Alain, additional, Cognard, Christophe, additional, Christine Januel, Anne, additional, Olivot, Jean-Marc, additional, Raposo, Nicolas, additional, Bonneville, Fabrice, additional, Touze, Emmanuel, additional, Barbier, Charlotte, additional, Schneckenburger, Romain, additional, Boulanger, Marion, additional, Cogez, Julien, additional, and Guettier, Sophie, additional

Published
2020
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20. Predictors of Parenchymal Hematoma After Mechanical Thrombectomy

Author

Boisseau, William, Fahed, Robert, Lapergue, Bertrand, Desilles, Jean-Philippe, Zuber, Kevin, Khoury, Naim, Garcia, Jeanne, Maïer, Benjamin, Redjem, Hocine, Ciccio, Gabriele, Smajda, Stanislas, Escalard, Simon, Taylor, Guillaume, Mazighi, Mikael, Piotin, Michel, Gory, Benjamin, Blanc, Raphaël, Decroix, Jean-Pierre, Wang, Adrien, Evrard, Serge, Tchikviladzé, Maya, Bourdain, Frederic, Afanasiev, Vadim, Majhadi, Loubna, Consoli, Arthuro, Di Maria, Federico, Coskun, Oguzhan, Rodesch, Georges, Lopez, Delphine, Sabben, Candice, Ben Maacha, Malek, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Corabianu, Ovide, De Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Obadia, Mickael, Ille, Olivier, Manchon, Eric, Garcia, Pierre-Yves, Riva, Roberto, Labeyrie, Paul-Emile, Nighoghossian, Norbert, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne-Evelyne, Hôpital de la Fondation Ophtalmologique Adolphe de Rothschild [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Foch [Suresnes], Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Université Sorbonne Paris Nord, Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], and Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)

Subjects
[INFO.INFO-IM]Computer Science [cs]/Medical Imaging, [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

International audience; Background and Purpose— Parenchymal hematoma (PH) is a rare but dreadful complication of acute ischemic stroke with unclear underlying mechanisms. We aimed to study the incidence and predictors of PH after mechanical thrombectomy. Methods— Data from a prospective observational multicenter registry was screened to identify acute ischemic stroke patients with an anterior circulation large vessel occlusion who underwent mechanical thrombectomy. Clinical, imaging, and procedural characteristics were used for the analysis, including brain imaging systematically performed at 24 hours. PH occurrence was assessed according to ECASS (European Collaborative Acute Stroke Study) criteria. Univariate and multivariable analyses were performed to identify predictors of PH. Results— A total of 1316 patients were included in the study. PH occurred in 153 out of 1316 patients (11.6%) and was associated with a lower rate of favorable outcome and increased mortality. On multivariable analysis, age (per 1 year increase, odds ratio [OR], 1.01; 95% CI, 1.00–1.03; P =0.05), current smoking (OR, 2.02; 95% CI, 1.32–3.09; P

Published
2019

21. Post-Thrombolysis Recanalization in Stroke Referrals for Thrombectomy

Author

Seners, Pierre, Turc, Guillaume, Naggara, Olivier, Hénon, Hilde, Piotin, Michel, Arquizan, Caroline, Cho, Tae-Hee, Narata, Ana-Paula, Lapergue, Bertrand, Richard, Sébastien, Legrand, Laurence, Bricout, Nicolas, Blanc, Raphaël, Dargazanli, Cyril, Gory, Benjamin, Debiais, Séverine, Tisserand, Marie, Bracard, Serge, Leclerc, Xavier, Obadia, Michael, Costalat, Vincent, Berner, Lise-Prune, Cottier, Jean-Philippe, Consoli, Arturo, Ducrocq, Xavier, Mas, Jean-Louis, Oppenheim, Catherine, Baron, Jean-Claude, Abrivard, Marie, Alamowitch, Sonia, Ben Hassen, Wagih, Berthezène, Yves, Blanc-Lasserre, Karine, Boulin, Anne, Boulouis, Grégoire, Bouly, Stephane, Bourdain, Frédéric, Calvet, David, Charron, Vladimir, Chbicheb, Mohamed, Condette-Auliac, Stéphanie, Corabianu, Ovide, Cordonnier, Charlotte, Coskun, Oguzhan, De Broucker, Thomas, Decroix, Jean-Pierre, Di Maria, Federico, Evrard, Serge, Fissellier, Mathieu, Girard, Isabelle, Lalu, Thibault, Le Coz, Patrick, Le Guen, Morgan, Ille, Olivier, Leys, Didier, Magni, Christophe, Manchon, Eric, Mazighi, Mikael, Mounier-Vehier, François, Moynier, Marinette, Muresan, Ioan-Paul, Nighoghossian, Norbert, Ong, Elodie, Ozsancak, Canan, Philippeau, Frédéric, Pico, Fernando, Rodesch, Georges, Rosolacci, Thierry, Sabben, Candice, Sablot, Denis, Tassan, Philippe, Tchikviladze, Maya, Turjman, Francis, Vallet, Anne-Evelyne, Wang, Adrien, Zins, Marc, Zuber, Mathieu, Centre Hospitalier Sainte Anne [Paris], Institut de psychiatrie et neurosciences (U894 / UMS 1266), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de neurologie[Lille], Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Fondation Ophtalmologique Adolphe de Rothschild [Paris], Département de neurologie [Montpellier], Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier]-Université de Montpellier (UM), Cerebrovascular Unit [Lyon], Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Service de neuroradiologie [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Hôpital Foch [Suresnes], Service de neurologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Services de neuroradiologie [Lille], Hôpital Roger Salengro-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département de Neuroradiologie[Montpellier], Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Université de Montpellier (UM), Hospices Civils de Lyon (HCL), Centre hospitalier régional Metz-Thionville (CHR Metz-Thionville), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Département de neurologie [Lille], Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [CHU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université de Montpellier (UM), Hôpital Roger Salengro [Lille]-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), and Hôpital Gui de Chauliac [Montpellier]-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Université de Montpellier (UM)

Subjects
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, thrombectomy, incidence, magnetic resonance imaging, fibrinolysis, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], stroke
Abstract

International audience; Background and Purpose—Whether all acute stroke patients with large vessel occlusion need to undergo intravenous thrombolysis before mechanical thrombectomy (MT) is debated as (1) the incidence of post-thrombolysis early recanalization (ER) is still unclear; (2) thrombolysis may be harmful in patients unlikely to recanalize; and, conversely, (3) transfer for MT may be unnecessary in patients highly likely to recanalize. Here, we determined the incidence and predictors of post-thrombolysis ER in patients referred for MT and derive ER prediction scores for trial design. Methods—Registries from 4 MT-capable centers gathering patients referred for MT and thrombolyzed either on site (mothership) or in a non MT-capable center (drip-and-ship) after magnetic resonance– or computed tomography–based imaging between 2015 and 2017. ER was identified on either first angiographic run or noninvasive imaging. In the magnetic resonance imaging subsample, thrombus length was determined on T2*-based susceptibility vessel sign. Independent predictors of no- ER were identified using multivariable logistic regression models, and scores were developed according to the magnitude of regression coefficients. Similar registries from 4 additional MT-capable centers were used as validation cohort. Results—In the derivation cohort (N=633), ER incidence was ≈20%. In patients with susceptibility vessel sign (n=498), no-ER was independently predicted by long thrombus, proximal occlusion, and mothership paradigm. A 6-point score derived from these variables showed strong discriminative power for no-ER (C statistic, 0.854) and was replicated in the validation cohort (n=353; C statistic, 0.888). A second score derived from the whole sample (including negative T2* or computed tomography–based imaging) also showed good discriminative power and was similarly validated. Highest grades on both scores predicted no-ER with >90% specificity, whereas low grades did not reliably predict ER. Conclusions—The substantial ER rate underlines the benefits derived from thrombolysis in bridging populations. Both prediction scores afforded high specificity for no-ER, but not for ER, which has implications for trial design.

Published
2018

22. Juvenile amyotrophic lateral sclerosis associated with biallelic c.757delG mutation of sorbitol dehydrogenase gene.

Author

Bernard, Emilien, Pegat, Antoine, Vallet, Anne-Evelyne, Leblanc, Pascal, Lumbroso, Serge, Mouzat, Kevin, and Latour, Philippe

Subjects
AMYOTROPHIC lateral sclerosis, SORBITOL, MOTOR neuron diseases, CHARCOT-Marie-Tooth disease, GENETIC mutation, GLUCOSE-6-phosphate dehydrogenase deficiency
Abstract

Mutation in the sorbitol dehydrogenase gene (SORD) has been recently described to cause axonal Charcot-Marie-Tooth disease (CMT), intermediate CMT, and distal hereditary motor neuropathy (dHMN). We herein report the case of a 24-year-old patient diagnosed with juvenile amyotrophic lateral sclerosis (JALS) who carried the homozygous c.757delG mutation in SORD. No other pathogenic variant in frequent JALS-causative genes was found. Our findings expand the phenotype related to SORD mutation, a new and potentially treatable genetic disease. [ABSTRACT FROM AUTHOR]

Published
2022
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23. Higher Annual Operator Volume Is Associated With Better Reperfusion Rates in Stroke Patients Treated by Mechanical Thrombectomy

Author

El Nawar, Rody, primary, Lapergue, Bertrand, additional, Piotin, Michel, additional, Gory, Benjamin, additional, Blanc, Raphael, additional, Consoli, Arturo, additional, Rodesch, Georges, additional, Mazighi, Mikael, additional, Bourdain, Frederic, additional, Kyheng, Maéva, additional, Labreuche, Julien, additional, Pico, Fernando, additional, Blanc, Raphaël, additional, Redjem, Hocine, additional, Escalard, Simon, additional, Desilles, Jean-Philippe, additional, Ciccio, Gabriele, additional, Smajda, Stanislas, additional, Fahed, Robert, additional, Obadia, Michael, additional, Sabben, Candice, additional, Corabianu, Ovide, additional, de Broucker, Thomas, additional, Smadja, Didier, additional, Alamowitch, Sonia, additional, Ille, Olivier, additional, Manchon, Eric, additional, Garcia, Pierre-Yves, additional, Taylor, Guillaume, additional, Ben Maacha, Malek, additional, Bourdain, Frédéric, additional, Decroix, Jean-Pierre, additional, Wang, Adrien, additional, Evrard, Serge, additional, Tchikviladze, Maya, additional, Coskun, Oguzhan, additional, Di Maria, Federico, additional, Leguen, Morgan, additional, Tisserand, Marie, additional, Rakotoharinandrasana, Haja, additional, Tassan, Philippe, additional, Poll, Roxanna, additional, Labeyrie, Paul Emile, additional, Riva, Roberto, additional, Turjman, Francis, additional, Nighoghossian, Norbert, additional, Derex, Laurent, additional, Cho, Tae-Hee, additional, Mechtouff, Laura, additional, Lukaszewicz, Anne-Claire, additional, Philippeau, Frédéric, additional, Cakmak, Serkan, additional, Blanc-Lasserre, Karine, additional, and Vallet, Anne-Evelyne, additional

Published
2019
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29. Absence of Airway Secretion Accumulation Predicts Tolerance of Noninvasive Ventilation in Subjects With Amyotrophic Lateral Sclerosis.

Author

Vandenberghe, Nadia, Vallet, Anne-Evelyne, Petitjean, Thierry, Le Cam, Pierre, Peysson, Stéphane, Guérin, Claude, Dailler, Frédéric, Jay, Sylvie, Cadiergue, Vincent, Bouhour, Françoise, Court-Fortune, Isabelle, Camdessanche, Jean-Philippe, Antoine, Jean-Christophe, Philit, François, Beuret, Pascal, Bin-Dorel, Sylvie, Vial, Christophe, and Broussolle, Emmanuel

Subjects
AMYOTROPHIC lateral sclerosis, CHI-squared test, CONFIDENCE intervals, EPIDEMIOLOGY, FISHER exact test, GOODNESS-of-fit tests, RESEARCH methodology, REGRESSION analysis, RESEARCH funding, U-statistics, DATA analysis, DATA analysis software, DESCRIPTIVE statistics, PROGNOSIS
Abstract

OBJECTIVE: To assess factors that predict good tolerance of noninvasive ventilation (NIV), in order to improve survival and quality of life in subjects with amyotrophic lateral sclerosis. METHODS: We conducted a prospective study in subjects with amyotrophic lateral sclerosis and requiring NIV. The primary end point was NIV tolerance at 1 month. Subjects, several of whom failed to complete the study, were classified as "tolerant" or "poorly tolerant," according to the number of hours of NIV use (more or less than 4 h per night, respectively). RESULTS: Eighty-one subjects, 73 of whom also attended the 1-month follow-up visit, participated over 34 months. NIV tolerance after the first day of utilization predicted tolerance at 1 month (77.6% and 75.3% of subjects, respectively). Multivariate analysis disclosed 3 factors predicting good NIV tolerance: absence of airway secretions accumulation prior to NIV onset (odds ratio 11.5); normal bulbar function at initiation of NIV (odds ratio 8.5); and older age (weakly significant, odds ratio 1.1). CONCLUSION: Our study reveals 3 factors that are predictive of good NIV tolerance, in particular the absence of airway secretion accumulation, which should prompt NIV initiation before its appearance. [ABSTRACT FROM AUTHOR]

Published
2013
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30. Initial neuro-ophthalmological manifestations in Churg -- Strauss syndrome.

Author

Vallet, Anne-Evelyne, Didelot, Adrien, Guebre-Egziabher, Fitsum, Bernard, Martine, and Mauguière, François

Abstract

Churg -- Strauss syndrome (CSS) is a systemic vasculitis with frequent respiratory tract involvement. It can also affect the nervous system, notably the optic tract. The present work reports the case of a 65-year-old man diagnosed as having CSS in the context of several acute onset neurological symptoms including muscle weakness and signs of temporal arteritis, including bilateral anterior ischaemic optic neuropathy (ON). Electroretinograms (ERGs) and visual evoked potentials (VEPs) were performed. Flash ERGs were normal whereas VEPs were highly abnormal, showing a dramatic voltage reduction, thus confirming the ON. The vision outcome was poor. Ophthalmological presentations of CSS have rarely been reported, but no previous case of sudden blindness documented by combined ERG and VEP investigations were found in the literature. The present case strongly suggests that the occurrence of visual loss in the context of systemic inflammation with hypereosinophilia should lead to considering the diagnosis of CSS. [ABSTRACT FROM AUTHOR]

Published
2010

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