Search

Your search keyword '"Valentini, Vincenzo"' showing total 3,002 results
Start Over Author "Valentini, Vincenzo"
3,002 results on '"Valentini, Vincenzo"'

2. Radiomics-enhanced early regression index for predicting treatment response in rectal cancer: a multi-institutional 0.35 T MRI-guided radiotherapy study

Author

Boldrini, Luca, Chiloiro, Giuditta, Cusumano, Davide, Yadav, Poonam, Yu, Gao, Romano, Angela, Piras, Antonio, Votta, Claudio, Placidi, Lorenzo, Broggi, Sara, Catucci, Francesco, Lenkowicz, Jacopo, Indovina, Luca, Bassetti, Michael F., Yang, Yingli, Fiorino, Claudio, Valentini, Vincenzo, and Gambacorta, Maria Antonietta

Published
2024
Full Text
View/download PDF

3. Error-Correcting Methodology for Evaluating Compliance to Clinical Guidelines: A Case Study on Rectal Cancer

Author

Savino, Mariachiara, Fernandez-Llatas, Carlos, Gatta, Roberto, Chiloiro, Giuditta, Di Franco, Silvia, Ibanez-Sanchez, Gema, Valero-Ramon, Zoe, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Damiani, Andrea, van der Aalst, Wil, Series Editor, Ram, Sudha, Series Editor, Rosemann, Michael, Series Editor, Szyperski, Clemens, Series Editor, Guizzardi, Giancarlo, Series Editor, De Smedt, Johannes, editor, and Soffer, Pnina, editor

Published
2024
Full Text
View/download PDF

4. A joint ESTRO and AAPM guideline for development, clinical validation and reporting of artificial intelligence models in radiation therapy

Author

Hurkmans, Coen, Bibault, Jean-Emmanuel, Brock, Kristy K., van Elmpt, Wouter, Feng, Mary, David Fuller, Clifton, Jereczek-Fossa, Barbara A., Korreman, Stine, Landry, Guillaume, Madesta, Frederic, Mayo, Chuck, McWilliam, Alan, Moura, Filipe, Muren, Ludvig P., El Naqa, Issam, Seuntjens, Jan, Valentini, Vincenzo, and Velec, Michael

Published
2024
Full Text
View/download PDF

5. Correction: Lung cancer multi-omics digital human avatars for integrating precision medicine into clinical practice: the LANTERN study

Author

Lococo, Filippo, Boldrini, Luca, Diepriye, Charles-Davies, Evangelista, Jessica, Nero, Camilla, Flamini, Sara, Minucci, Angelo, De Paolis, Elisa, Vita, Emanuele, Cesario, Alfredo, Annunziata, Salvatore, Calcagni, Maria Lucia, Chiappetta, Marco, Cancellieri, Alessandra, Larici, Anna Rita, Cicchetti, Giuseppe, Troost, Esther G. C., Ádány, Róza, Farré, Núria, Öztürk, Ece, Van Doorne, Dominique, Leoncini, Fausto, Urbani, Andrea, Trisolini, Rocco, Bria, Emilio, Giordano, Alessandro, Rindi, Guido, Sala, Evis, Tortora, Giampaolo, Valentini, Vincenzo, Boccia, Stefania, Margaritora, Stefano, and Scambia, Giovanni

Published
2023
Full Text
View/download PDF

6. May we routinely spare hippocampal region in primary central nervous system lymphoma during whole brain radiotherapy?

Author

Mazzarella, Ciro, Chiesa, Silvia, Toppi, Lucrezia, Hohaus, Stefan, Gaudino, Simona, D’Alo, Francesco, Dinapoli, Nicola, Davide, Resta, Zinicola, Tiziano, Bracci, Serena, Martino, Antonella, Beghella Bartoli, Francesco, Lepre, Elisabetta, Bertolini, Roberta, Mariani, Silvia, Colosimo, Cesare, Frascino, Vincenzo, Mattiucci, Gian Carlo, Gambacorta, Maria Antonietta, Valentini, Vincenzo, and Balducci, Mario

Published
2023
Full Text
View/download PDF

7. The Italian version of the Pediatric Quality of Life Inventory™ (PEDSQL™) 3.0 healthcare satisfaction hematology/oncology module: reliability and validity in radiation oncology

Author

Marconi, Elisa, Beghella Bartoli, Francesco, Meldolesi, Elisa, Mariani, Silvia, Panza, Giulia, Nardangeli, Alessia, Dinapoli, Loredana, Lees, Teresa Carmen, Guido, Antonella, Mastronuzzi, Angela, Ruggiero, Antonio, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Balducci, Mario, Chieffo, Daniela Pia Rosaria, and Chiesa, Silvia

Published
2023
Full Text
View/download PDF

8. Lung cancer multi-omics digital human avatars for integrating precision medicine into clinical practice: the LANTERN study

Author

Lococo, Filippo, Boldrini, Luca, Diepriye, Charles-Davies, Evangelista, Jessica, Nero, Camilla, Flamini, Sara, Minucci, Angelo, De Paolis, Elisa, Vita, Emanuele, Cesario, Alfredo, Annunziata, Salvatore, Calcagni, Maria Lucia, Chiappetta, Marco, Cancellieri, Alessandra, Larici, Anna Rita, Cicchetti, Giuseppe, Troost, Esther G.C., Ádány, Róza, Farré, Núria, Öztürk, Ece, Van Doorne, Dominique, Leoncini, Fausto, Urbani, Andrea, Trisolini, Rocco, Bria, Emilio, Giordano, Alessandro, Rindi, Guido, Sala, Evis, Tortora, Giampaolo, Valentini, Vincenzo, Boccia, Stefania, Margaritora, Stefano, and Scambia, Giovanni

Published
2023
Full Text
View/download PDF

9. Magnetic resonance guided SBRT reirradiation in locally recurrent prostate cancer: a multicentric retrospective analysis

Author

Boldrini, Luca, Romano, Angela, Chiloiro, Giuditta, Corradini, Stefanie, De Luca, Viola, Verusio, Valeria, D’Aviero, Andrea, Castelluccia, Alessandra, Alitto, Anna Rita, Catucci, Francesco, Grimaldi, Gianmarco, Trapp, Christian, Hörner-Rieber, Juliane, Marchesano, Domenico, Frascino, Vincenzo, Mattiucci, Gian Carlo, Valentini, Vincenzo, Gentile, Piercarlo, and Gambacorta, Maria Antonietta

Published
2023
Full Text
View/download PDF

12. Gastric Cancer

Author

Cellini, Francesco, Casà, Calogero, D’Aviero, Andrea, Valentini, Vincenzo, Grosu, Anca-Ligia, editor, Nieder, Carsten, editor, and Nicolay, Nils Henrik, editor

Published
2023
Full Text
View/download PDF

13. Rectal Cancer

Author

Fokas, Emmanouil, Gani, Cihan, Valentini, Vincenzo, Rödel, Claus, Gambacorta, Maria Antonietta, Grosu, Anca-Ligia, editor, Nieder, Carsten, editor, and Nicolay, Nils Henrik, editor

Published
2023
Full Text
View/download PDF

18. An Interactive Dashboard for Patient Monitoring and Management: A Support Tool to the Continuity of Care Centre

Author

Savino, Mariachiara, Acampora, Nicola, Masciocchi, Carlotta, Gatta, Roberto, Dachena, Chiara, Orini, Stefania, Cambieri, Andrea, Landi, Francesco, Onder, Graziano, Russo, Andrea, Salini, Sara, Valentini, Vincenzo, Damiani, Andrea, Patarnello, Stefano, Barillaro, Christian, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Juarez, Jose M., editor, Marcos, Mar, editor, Stiglic, Gregor, editor, and Tucker, Allan, editor

Published
2023
Full Text
View/download PDF

21. The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping

Author

Zwanenburg, Alex, Vallières, Martin, Abdalah, Mahmoud A, Aerts, Hugo JWL, Andrearczyk, Vincent, Apte, Aditya, Ashrafinia, Saeed, Bakas, Spyridon, Beukinga, Roelof J, Boellaard, Ronald, Bogowicz, Marta, Boldrini, Luca, Buvat, Irène, Cook, Gary JR, Davatzikos, Christos, Depeursinge, Adrien, Desseroit, Marie-Charlotte, Dinapoli, Nicola, Dinh, Cuong Viet, Echegaray, Sebastian, El Naqa, Issam, Fedorov, Andriy Y, Gatta, Roberto, Gillies, Robert J, Goh, Vicky, Götz, Michael, Guckenberger, Matthias, Ha, Sung Min, Hatt, Mathieu, Isensee, Fabian, Lambin, Philippe, Leger, Stefan, Leijenaar, Ralph TH, Lenkowicz, Jacopo, Lippert, Fiona, Losnegård, Are, Maier-Hein, Klaus H, Morin, Olivier, Müller, Henning, Napel, Sandy, Nioche, Christophe, Orlhac, Fanny, Pati, Sarthak, Pfaehler, Elisabeth AG, Rahmim, Arman, Rao, Arvind UK, Scherer, Jonas, Siddique, Muhammad Musib, Sijtsema, Nanna M, Socarras Fernandez, Jairo, Spezi, Emiliano, Steenbakkers, Roel JHM, Tanadini-Lang, Stephanie, Thorwarth, Daniela, Troost, Esther GC, Upadhaya, Taman, Valentini, Vincenzo, van Dijk, Lisanne V, van Griethuysen, Joost, van Velden, Floris HP, Whybra, Philip, Richter, Christian, and Löck, Steffen

Subjects
Biomedical Imaging, Cancer, Bioengineering, Clinical Trials and Supportive Activities, Clinical Research, Good Health and Well Being, Biomarkers, Calibration, Fluorodeoxyglucose F18, Humans, Image Processing, Computer-Assisted, Lung Neoplasms, Magnetic Resonance Imaging, Phantoms, Imaging, Phenotype, Positron-Emission Tomography, Radiopharmaceuticals, Reproducibility of Results, Sarcoma, Software, Tomography, X-Ray Computed, Medical and Health Sciences, Nuclear Medicine & Medical Imaging
Abstract

Background Radiomic features may quantify characteristics present in medical imaging. However, the lack of standardized definitions and validated reference values have hampered clinical use. Purpose To standardize a set of 174 radiomic features. Materials and Methods Radiomic features were assessed in three phases. In phase I, 487 features were derived from the basic set of 174 features. Twenty-five research teams with unique radiomics software implementations computed feature values directly from a digital phantom, without any additional image processing. In phase II, 15 teams computed values for 1347 derived features using a CT image of a patient with lung cancer and predefined image processing configurations. In both phases, consensus among the teams on the validity of tentative reference values was measured through the frequency of the modal value and classified as follows: less than three matches, weak; three to five matches, moderate; six to nine matches, strong; 10 or more matches, very strong. In the final phase (phase III), a public data set of multimodality images (CT, fluorine 18 fluorodeoxyglucose PET, and T1-weighted MRI) from 51 patients with soft-tissue sarcoma was used to prospectively assess reproducibility of standardized features. Results Consensus on reference values was initially weak for 232 of 302 features (76.8%) at phase I and 703 of 1075 features (65.4%) at phase II. At the final iteration, weak consensus remained for only two of 487 features (0.4%) at phase I and 19 of 1347 features (1.4%) at phase II. Strong or better consensus was achieved for 463 of 487 features (95.1%) at phase I and 1220 of 1347 features (90.6%) at phase II. Overall, 169 of 174 features were standardized in the first two phases. In the final validation phase (phase III), most of the 169 standardized features could be excellently reproduced (166 with CT; 164 with PET; and 164 with MRI). Conclusion A set of 169 radiomics features was standardized, which enabled verification and calibration of different radiomics software. © RSNA, 2020 Online supplemental material is available for this article. See also the editorial by Kuhl and Truhn in this issue.

Published
2020

22. Predictive and prognostic value of inflammatory markers in locally advanced rectal cancer (PILLAR) – A multicentric analysis by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gastrointestinal Study Group

Author

Chiloiro, Giuditta, Romano, Angela, Mariani, Silvia, Macchia, Gabriella, Giannarelli, Diana, Caravatta, Luciana, Franco, Pierfrancesco, Boldrini, Luca, Arcelli, Alessandra, Bacigalupo, Almalina, Belgioia, Liliana, Fontana, Antonella, Meldolesi, Elisa, Montesi, Giampaolo, Niespolo, Rita Marina, Palazzari, Elisa, Piva, Cristina, Valentini, Vincenzo, and Gambacorta, Maria Antonietta

Published
2023
Full Text
View/download PDF

23. A predictive model of polymetastatic disease from a multicenter large retrospectIve database on colorectal lung metastases treated with stereotactic ablative radiotherapy: The RED LaIT-SABR study

Author

Nicosia, Luca, Franceschini, Davide, Perrone-Congedi, Francesca, Molinari, Alessandro, Gerardi, Marianna Alessandra, Rigo, Michele, Mazzola, Rosario, Perna, Marco, Scotti, Vieri, Fodor, Andrei, Iurato, Aurelia, Pasqualetti, Francesco, Gadducci, Giovanni, Chiesa, Silvia, Niespolo, Rita Marina, Bruni, Alessio, Cappelli, Anna, D'Angelo, Elisa, Borghetti, Paolo, Di Marzo, Alessandro, Ravasio, Andrea, De Bari, Berardino, Sepulcri, Matteo, Aiello, Dario, Mortellaro, Gianluca, Sangalli, Claudia, Franceschini, Marzia, Montesi, Giampaolo, Aquilanti, Francesco Maria, Lunardi, Gianluigi, Valdagni, Riccardo, Fazio, Ivan, Scarzello, Giovanni, Vavassori, Vittorio, Maranzano, Ernesto, Maria Magrini, Stefano, Arcangeli, Stefano, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Paiar, Fabiola, Ramella, Sara, Di Muzio, Nadia Gisella, Loi, Mauro, Jereczek-Fossa, Barbara Alicja, Casamassima, Franco, Osti, Mattia Falchetto, Scorsetti, Marta, and Alongi, Filippo

Published
2023
Full Text
View/download PDF

24. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines

Author

Cavestro, Giulia Martina, Mannucci, Alessandro, Balaguer, Francesc, Hampel, Heather, Kupfer, Sonia S., Repici, Alessandro, Sartore-Bianchi, Andrea, Seppälä, Toni T., Valentini, Vincenzo, Boland, Clement Richard, Brand, Randall E., Buffart, Tineke E., Burke, Carol A., Caccialanza, Riccardo, Cannizzaro, Renato, Cascinu, Stefano, Cercek, Andrea, Crosbie, Emma J., Danese, Silvio, Dekker, Evelien, Daca-Alvarez, Maria, Deni, Francesco, Dominguez-Valentin, Mev, Eng, Cathy, Goel, Ajay, Guillem, Josè G., Houwen, Britt B.S.L., Kahi, Charles, Kalady, Matthew F., Kastrinos, Fay, Kühn, Florian, Laghi, Luigi, Latchford, Andrew, Liska, David, Lynch, Patrick, Malesci, Alberto, Mauri, Gianluca, Meldolesi, Elisa, Møller, Pål, Monahan, Kevin J., Möslein, Gabriela, Murphy, Caitlin C., Nass, Karlijn, Ng, Kimmie, Oliani, Cristina, Papaleo, Enrico, Patel, Swati G., Puzzono, Marta, Remo, Andrea, Ricciardiello, Luigi, Ripamonti, Carla Ida, Siena, Salvatore, Singh, Satish K., Stadler, Zsofia K., Stanich, Peter P., Syngal, Sapna, Turi, Stefano, Urso, Emanuele Damiano, Valle, Laura, Vanni, Valeria Stella, Vilar, Eduardo, Vitellaro, Marco, You, Yi-Qian Nancy, Yurgelun, Matthew B., Zuppardo, Raffaella Alessia, and Stoffel, Elena M.

Published
2023
Full Text
View/download PDF

25. A Machine Learning Predictive Model of Bloodstream Infection in Hospitalized Patients

Author

Murri, Rita, De Angelis, Giulia, Antenucci, Laura, Fiori Alfarano, Barbara, Rinaldi, Riccardo, Fantoni, Massimo, Damiani, Andrea, Patarnello, Stefano, Sanguinetti, Maurizio, Valentini, Vincenzo, Posteraro, Brunella, Masciocchi, Carlotta, Murri, Rita (ORCID:0000-0003-4263-7854), De Angelis, Giulia (ORCID:0000-0002-7087-7399), Fiori, Barbara (ORCID:0000-0003-3318-5809), Fantoni, Massimo (ORCID:0000-0001-6913-8460), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Posteraro, Brunella (ORCID:0000-0002-1663-7546), Murri, Rita, De Angelis, Giulia, Antenucci, Laura, Fiori Alfarano, Barbara, Rinaldi, Riccardo, Fantoni, Massimo, Damiani, Andrea, Patarnello, Stefano, Sanguinetti, Maurizio, Valentini, Vincenzo, Posteraro, Brunella, Masciocchi, Carlotta, Murri, Rita (ORCID:0000-0003-4263-7854), De Angelis, Giulia (ORCID:0000-0002-7087-7399), Fiori, Barbara (ORCID:0000-0003-3318-5809), Fantoni, Massimo (ORCID:0000-0001-6913-8460), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), and Posteraro, Brunella (ORCID:0000-0002-1663-7546)

Abstract

The aim of the study was to build a machine learning-based predictive model to discriminate between hospitalized patients at low risk and high risk of bloodstream infection (BSI). A Data Mart including all patients hospitalized between January 2016 and December 2019 with suspected BSI was built. Multivariate logistic regression was applied to develop a clinically interpretable machine learning predictive model. The model was trained on 2016-2018 data and tested on 2019 data. A feature selection based on a univariate logistic regression first selected candidate predictors of BSI. A multivariate logistic regression with stepwise feature selection in five-fold cross-validation was applied to express the risk of BSI. A total of 5660 hospitalizations (4026 and 1634 in the training and the validation subsets, respectively) were included. Eleven predictors of BSI were identified. The performance of the model in terms of AUROC was 0.74. Based on the interquartile predicted risk score, 508 (31.1%) patients were defined as being at low risk, 776 (47.5%) at medium risk, and 350 (21.4%) at high risk of BSI. Of them, 14.2% (72/508), 30.8% (239/776), and 64% (224/350) had a BSI, respectively. The performance of the predictive model of BSI is promising. Computational infrastructure and machine learning models can help clinicians identify people at low risk for BSI, ultimately supporting an antibiotic stewardship approach.

Published
2024

26. A novel risk score predicting 30-day hospital re-admission of patients with acute stroke by machine learning model

Author

Mercurio, Giovanna, Gottardelli, Benedetta, Lenkowicz, Jacopo, Patarnello, Stefano, Bellavia, Simone, Scala, Irene, Rizzo, Pierandrea, de Belvis, Antonio Giulio, Del Signore, Anna Benedetta, Maviglia, Riccardo, Bocci, Maria Grazia, Olivi, Alessandro, Franceschi, Francesco, Urbani, Andrea, Calabresi, Paolo, Valentini, Vincenzo, Antonelli, Massimo, Frisullo, Giovanni, Olivi, Alessandro (ORCID:0000-0002-4489-7564), Franceschi, Francesco (ORCID:0000-0001-6266-445X), Urbani, Andrea (ORCID:0000-0001-9168-3174), Calabresi, Paolo (ORCID:0000-0003-0326-5509), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Antonelli, Massimo (ORCID:0000-0003-3007-1670), Mercurio, Giovanna, Gottardelli, Benedetta, Lenkowicz, Jacopo, Patarnello, Stefano, Bellavia, Simone, Scala, Irene, Rizzo, Pierandrea, de Belvis, Antonio Giulio, Del Signore, Anna Benedetta, Maviglia, Riccardo, Bocci, Maria Grazia, Olivi, Alessandro, Franceschi, Francesco, Urbani, Andrea, Calabresi, Paolo, Valentini, Vincenzo, Antonelli, Massimo, Frisullo, Giovanni, Olivi, Alessandro (ORCID:0000-0002-4489-7564), Franceschi, Francesco (ORCID:0000-0001-6266-445X), Urbani, Andrea (ORCID:0000-0001-9168-3174), Calabresi, Paolo (ORCID:0000-0003-0326-5509), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), and Antonelli, Massimo (ORCID:0000-0003-3007-1670)

Abstract

Background: The 30-day hospital re-admission rate is a quality measure of hospital care to monitor the efficiency of the healthcare system. The hospital re-admission of acute stroke (AS) patients is often associated with higher mortality rates, greater levels of disability and increased healthcare costs. The aim of our study was to identify predictors of unplanned 30-day hospital re-admissions after discharge of AS patients and define an early re-admission risk score (RRS).Methods: This observational, retrospective study was performed on AS patients who were discharged between 2014 and 2019. Early re-admission predictors were identified by machine learning models. The performances of these models were assessed by receiver operating characteristic curve analysis.Results: Of 7599 patients with AS, 3699 patients met the inclusion criteria, and 304 patients (8.22%) were re-admitted within 30 days from discharge. After identifying the predictors of early re-admission by logistic regression analysis, RRS was obtained and consisted of seven variables: hemoglobin level, atrial fibrillation, brain hemorrhage, discharge home, chronic obstructive pulmonary disease, one and more than one hospitalization in the previous year. The cohort of patients was then stratified into three risk categories: low (RRS = 0-1), medium (RRS = 2-3) and high (RRS >3) with re-admission rates of 5%, 8% and 14%, respectively.Conclusions: The identification of risk factors for early re-admission after AS and the elaboration of a score to stratify at discharge time the risk of re-admission can provide a tool for clinicians to plan a personalized follow-up and contain healthcare costs.

Published
2024

27. Vaccines and Myocardial Injury in Patients Hospitalized for COVID-19 Infection: the CardioCOVID-Gemelli Study

Author

Montone, Rocco Antonio, Rinaldi, Riccardo, Masciocchi, Carlotta, Lilli, Livia, Damiani, Andrea, La Vecchia, Giulia, Iannaccone, Giulia, Basile, Mattia, Salzillo, Carmine, Caff, Andrea, Bonanni, Alice, De Pascale, Gennaro, Grieco, Domenico Luca, Tanzarella, Eloisa Sofia, Buonsenso, Danilo, Murri, Rita, Fantoni, Massimo, Liuzzo, Giovanna, Sanna, Tommaso, Richeldi, Luca, Sanguinetti, Maurizio, Massetti, Massimo, Trani, Carlo, Tshomba, Yamume, Gasbarrini, Antonio, Valentini, Vincenzo, Antonelli, Massimo, Crea, Filippo, De Pascale, Gennaro (ORCID:0000-0002-8255-0676), Grieco, Domenico Luca (ORCID:0000-0002-4557-6308), Murri, Rita (ORCID:0000-0003-4263-7854), Fantoni, Massimo (ORCID:0000-0001-6913-8460), Liuzzo, Giovanna (ORCID:0000-0002-5714-0907), Sanna, Tommaso (ORCID:0000-0002-5760-6885), Richeldi, Luca (ORCID:0000-0001-8594-1448), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Massetti, Massimo (ORCID:0000-0002-7100-8478), Trani, Carlo (ORCID:0000-0001-9777-013X), Tshomba, Yamume (ORCID:0000-0001-7304-7553), Gasbarrini, Antonio (ORCID:0000-0002-7278-4823), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Antonelli, Massimo (ORCID:0000-0003-3007-1670), Crea, Filippo (ORCID:0000-0001-9404-8846), Montone, Rocco Antonio, Rinaldi, Riccardo, Masciocchi, Carlotta, Lilli, Livia, Damiani, Andrea, La Vecchia, Giulia, Iannaccone, Giulia, Basile, Mattia, Salzillo, Carmine, Caff, Andrea, Bonanni, Alice, De Pascale, Gennaro, Grieco, Domenico Luca, Tanzarella, Eloisa Sofia, Buonsenso, Danilo, Murri, Rita, Fantoni, Massimo, Liuzzo, Giovanna, Sanna, Tommaso, Richeldi, Luca, Sanguinetti, Maurizio, Massetti, Massimo, Trani, Carlo, Tshomba, Yamume, Gasbarrini, Antonio, Valentini, Vincenzo, Antonelli, Massimo, Crea, Filippo, De Pascale, Gennaro (ORCID:0000-0002-8255-0676), Grieco, Domenico Luca (ORCID:0000-0002-4557-6308), Murri, Rita (ORCID:0000-0003-4263-7854), Fantoni, Massimo (ORCID:0000-0001-6913-8460), Liuzzo, Giovanna (ORCID:0000-0002-5714-0907), Sanna, Tommaso (ORCID:0000-0002-5760-6885), Richeldi, Luca (ORCID:0000-0001-8594-1448), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Massetti, Massimo (ORCID:0000-0002-7100-8478), Trani, Carlo (ORCID:0000-0001-9777-013X), Tshomba, Yamume (ORCID:0000-0001-7304-7553), Gasbarrini, Antonio (ORCID:0000-0002-7278-4823), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Antonelli, Massimo (ORCID:0000-0003-3007-1670), and Crea, Filippo (ORCID:0000-0001-9404-8846)

Abstract

Background: Myocardial injury is prevalent among patients hospitalized for COVID-19. However, the role of COVID-19 vaccines in modifying the risk of myocardial injury is unknown. Objectives: To assess the role of vaccines in modifying the risk of myocardial injury in COVID-19. Methods: We enrolled COVID-19 patients admitted from March 2021 to February 2022 with known vaccination status and ≥1 assessment of hs-cTnI within 30 days from the admission. The primary endpoint was the occurrence of myocardial injury (hs-cTnI levels >99th percentile upper reference limit). Results: 1019 patients were included (mean age 67.7±14.8 years, 60.8% male, 34.5% vaccinated against COVID-19). Myocardial injury occurred in 145 (14.2%) patients. At multivariate logistic regression analysis, advanced age, chronic kidney disease and hypertension, but not vaccination status, were independent predictors of myocardial injury. In the analysis according to age tertiles distribution, myocardial injury occurred more frequently in the III tertile (≥76 years) compared to other tertiles (I tertile:≤60 years;II tertile:61-75 years) (p<0.001). Moreover, in the III tertile, vaccination was protective against myocardial injury (OR 0.57, CI 95% 0.34-0.94; p=0.03), while a previous history of coronary artery disease was an independent positive predictor. In contrast, in the I tertile, chronic kidney disease (OR 6.94, 95% CI 1.31-36.79, p=0.02) and vaccination (OR 4.44, 95% CI 1.28-15.34, p=0.02) were independent positive predictors of myocardial injury. Conclusions: In patients ≥76 years, COVID-19 vaccines were protective for the occurrence of myocardial injury, while in patients ≤60 years, myocardial injury was associated with previous COVID-19 vaccination. Further studies are warranted to clarify the underlying mechanisms.

Published
2024

29. Simultaneous Integrated Boost (Sib) Intensity-Modulated Radiotherapy for Treatment of Bone Metastases: Analysis of a Breast Cancer Cohort

Author

Marazzi, Fabio, primary, Masiello, Valeria, additional, Fabi, Alessandra, additional, Manfrida, Stefania, additional, Corvari, Barbara, additional, Lancellotta, Valentina, additional, Mazzarella, Ciro, additional, Longo, Silvia, additional, De Angeli, Martina, additional, Moschella, Francesca, additional, Di Leone, Alba, additional, Orlandi, Armando, additional, Bracci, Serena, additional, Colloca, Giuseppe Ferdinando, additional, Massaccesi, Mariangela, additional, Boldrini, Luca, additional, Tagliaferri, Luca, additional, Franceschini, Gianluca, additional, Bria, Emilio, additional, Masetti, Riccardo, additional, Valentini, Vincenzo, additional, Gambacorta, Maria Antonietta, additional, and CELLINI, Francesco, additional

Published
2024
Full Text
View/download PDF

30. Clinical Impact of Pathologic Residual Tumor in Locally Advanced Cervical Cancer Patients Managed by Chemoradiotherapy Followed by Radical Surgery: A Large, Multicenter, Retrospective Study

Author

Federico, Alex, Anchora, Luigi Pedone, Gallotta, Valerio, Fanfani, Francesco, Cosentino, Francesco, Turco, Luigi Carlo, Bizzarri, Nicolo’, Legge, Francesco, Teodorico, Elena, Macchia, Gabriella, Valentini, Vincenzo, Scambia, Giovanni, and Ferrandina, Gabriella

Published
2022
Full Text
View/download PDF

32. Current controversies in TNM for the radiological staging of rectal cancer and how to deal with them: results of a global online survey and multidisciplinary expert consensus

Author

Lambregts, Doenja M. J., Bogveradze, Nino, Blomqvist, Lennart K., Fokas, Emmanouil, Garcia-Aguilar, Julio, Glimelius, Bengt, Gollub, Marc J., Konishi, Tsuyoshi, Marijnen, Corrie A. M., Nagtegaal, Iris D., Nilsson, Per J., Perez, Rodrigo O., Snaebjornsson, Petur, Taylor, Stuart A., Tolan, Damian J. M., Valentini, Vincenzo, West, Nicholas P., Wolthuis, Albert, Lahaye, Max J., Maas, Monique, Beets, Geerard L., and Beets-Tan, Regina G.H.

Published
2022
Full Text
View/download PDF

33. Role of Peripheral Blood Markers for Detecting Response and Predicting Prognosis in Patients with Non-small-cell Lung Cancer Undergoing Neoadjuvant Therapy and Surgery

Author

Lococo, Filippo, Chiappetta, Marco, Evangelista, Jessica, Sperduti, Isabella, Nachira, Dania, Porziella, Venanzio, Congedo, Maria Teresa, Bria, Emilio, Vita, Emanuele, Cesario, Alfredo, Sassorossi, Carolina, Charles-Davies, Diepriye, Boldrini, Luca, Massaccesi, Mariangela, Valentini, Vincenzo, and Margaritora, Stefano

Published
2022
Full Text
View/download PDF

37. Ways to improve breast cancer patients' management and clinical outcome: The 2020 Assisi Think Tank Meeting

Author

Aristei, Cynthia, Bölükbaşı, Yasemin, Kaidar-Person, Orit, Pfeffer, Raphael, Arenas, Meritxell, Boersma, Liesbeth J., Ciabattoni, Antonella, Coles, Charlotte E., Franco, Pierfrancesco, Krengli, Marco, Leonardi, Maria Cristina, Marazzi, Fabio, Masiello, Valeria, Meattini, Icro, Montero, Angel, Offersen, Birgitte, Trigo, Maria Lurdes, Bourgier, Céline, Genovesi, Domenico, Kouloulias, Vassilis, Morganti, Alessio G., Meduri, Bruno, Pasinetti, Nadia, Pedretti, Sara, Perrucci, Elisabetta, Rivera, Sofia, Tombolini, Vincenzo, Vidali, Cristiana, Valentini, Vincenzo, and Poortmans, Philip

Published
2022
Full Text
View/download PDF

43. Clinical adoption patterns of 0.35 Tesla MR-guided radiation therapy in Europe and Asia

Author

Slotman, Berend J., Clark, Mary Ann, Özyar, Enis, Kim, Myungsoo, Itami, Jun, Tallet, Agnès, Debus, Jürgen, Pfeffer, Raphael, Gentile, PierCarlo, Hama, Yukihiro, Andratschke, Nicolaus, Riou, Olivier, Camilleri, Philip, Belka, Claus, Quivrin, Magali, Kim, BoKyong, Pedersen, Anders, van Overeem Felter, Mette, Kim, Young Il, Kim, Jin Ho, Fuss, Martin, and Valentini, Vincenzo

Published
2022
Full Text
View/download PDF

44. THUNDER 2: THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI guided radiotherapy

Author

Chiloiro, Giuditta, Cusumano, Davide, Boldrini, Luca, Romano, Angela, Placidi, Lorenzo, Nardini, Matteo, Meldolesi, Elisa, Barbaro, Brunella, Coco, Claudio, Crucitti, Antonio, Persiani, Roberto, Petruzziello, Lucio, Ricci, Riccardo, Salvatore, Lisa, Sofo, Luigi, Alfieri, Sergio, Manfredi, Riccardo, Valentini, Vincenzo, and Gambacorta, Maria Antonietta

Published
2022
Full Text
View/download PDF

45. BRIDGE −1 TRIAL: BReak Interval Delayed surgery for Gastrointestinal Extraperitoneal rectal cancer, a multicentric phase III randomized trial

Author

Chiloiro, Giuditta, Meldolesi, Elisa, Corvari, Barbara, Romano, Angela, Barbaro, Brunella, Coco, Claudio, Crucitti, Antonio, Genovesi, Domenico, Lupattelli, Marco, Mantello, Giovanna, Menghi, Roberta, Falchetto Osti, Mattia, Persiani, Roberto, Petruzziello, Lucio, Ricci, Riccardo, Sofo, Luigi, Valentini, Chiara, De Paoli, Antonino, Valentini, Vincenzo, and Antonietta Gambacorta, Maria

Published
2022
Full Text
View/download PDF

46. A real-time integrated framework to support clinical decision making for covid-19 patients

Author

Murri, Rita, Masciocchi, Carlotta, Lenkowicz, Jacopo, Fantoni, Massimo, Damiani, Andrea, Marchetti, Antonio, Sergi, Paolo Domenico Angelo, Arcuri, Giovanni, Cesario, Alfredo, Patarnello, Stefano, Antonelli, Massimo, Bellantone, Rocco, Bernabei, Roberto, Boccia, Stefania, Calabresi, Paolo, Cambieri, Andrea, Cauda, Roberto, Colosimo, Cesare, Crea, Filippo, De Maria, Ruggero, De Stefano, Valerio, Franceschi, Francesco, Gasbarrini, Antonio, Landolfi, Raffaele, Parolini, Ornella, Richeldi, Luca, Sanguinetti, Maurizio, Urbani, Andrea, Zega, Maurizio, Scambia, Giovanni, and Valentini, Vincenzo

Published
2022
Full Text
View/download PDF

47. Bayesian network structure for predicting local tumor recurrence in rectal cancer patients treated with neoadjuvant chemoradiation followed by surgery

Author

Osong, Biche, Masciocchi, Carlotta, Damiani, Andrea, Bermejo, Inigo, Meldolesi, Elisa, Chiloiro, Giuditta, Berbee, Maaike, Lee, Seok Ho, Dekker, Andre, Valentini, Vincenzo, Gerard, Jean-Pierre, Rödel, Claus, Bujko, Krzysztof, van de Velde, Cornelis, Folkesson, Joakim, Sainato, Aldo, Glynne-Jones, Robert, Ngan, Samuel, Brændengen, Morten, Sebag-Montefiore, David, and van Soest, Johan

Published
2022
Full Text
View/download PDF

49. Palliative radiotherapy indications during the COVID-19 pandemic and in future complex logistic settings: the NORMALITY model

Author

Cellini, Francesco, Di Franco, Rossella, Manfrida, Stefania, Borzillo, Valentina, Maranzano, Ernesto, Pergolizzi, Stefano, Morganti, Alessio Giuseppe, Fusco, Vincenzo, Deodato, Francesco, Santarelli, Mario, Arcidiacono, Fabio, Rossi, Romina, Reina, Sara, Merlotti, Anna, Jereczek-Fossa, Barbara Alicja, Tozzi, Angelo, Siepe, Giambattista, Cacciola, Alberto, Russi, Elvio, Gambacorta, Maria Antonietta, Scorsetti, Marta, Ricardi, Umberto, Corvò, Renzo, Donato, Vittorio, Muto, Paolo, and Valentini, Vincenzo

Published
2021
Full Text
View/download PDF

50. International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer

Author

Fokas, Emmanouil, Appelt, Ane, Glynne-Jones, Robert, Beets, Geerard, Perez, Rodrigo, Garcia-Aguilar, Julio, Rullier, Eric, Joshua Smith, J., Marijnen, Corrie, Peters, Femke P., van der Valk, Maxine, Beets-Tan, Regina, Myint, Arthur S., Gerard, Jean-Pierre, Bach, Simon P., Ghadimi, Michael, Hofheinz, Ralf D., Bujko, Krzysztof, Gani, Cihan, Haustermans, Karin, Minsky, Bruce D., Ludmir, Ethan, West, Nicholas P., Gambacorta, Maria A., Valentini, Vincenzo, Buyse, Marc, Renehan, Andrew G., Gilbert, Alexandra, Sebag-Montefiore, David, and Rödel, Claus

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results