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3. Clinical profile and management of patients with acute myocardial infarction admitted to cardiac care units: The EYESHOT-2 registry

Author

De Luca, Leonardo, Maggioni, Aldo Pietro, Cavallini, Claudio, Leonardi, Sergio, Lucci, Donata, Sacco, Alice, di Uccio, Fortunato Scotto, Valente, Serafina, Navazio, Alessandro, Pascale, Vittorio, Geraci, Giovanna, Lanni, Francesca, Gulizia, Michele Massimo, Colivicchi, Furio, Gabrielli, Domenico, and Oliva, Fabrizio

Published
2025
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7. Myocardial Work Indices Predict Hospitalization in Patients with Advanced Heart Failure

Author

Mandoli, Giulia Elena, primary, Landra, Federico, additional, Chiantini, Benedetta, additional, Bonadiman, Lorenzo, additional, Pastore, Maria Concetta, additional, Focardi, Marta, additional, D’Ascenzi, Flavio, additional, Lisi, Matteo, additional, Diviggiano, Enrico Emilio, additional, Martini, Luca, additional, Bernazzali, Sonia, additional, Valente, Serafina, additional, Maccherini, Massimo, additional, Cameli, Matteo, additional, and Henein, Michael Y., additional

Published
2024
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13. Myocardial work indices predict hospitalization in patients with advanced heart failure

Author

Mandoli, Giulia Elena, Landra, Federico, Chiantini, Benedetta, Bonadiman, Lorenzo, Pastore, Maria Concetta, Focardi, Marta, D’Ascenzi, Flavio, Lisi, Matteo, Diviggiano, Enrico Emilio, Martini, Luca, Bernazzali, Sonia, Valente, Serafina, Maccherini, Massimo, Cameli, Matteo, Henein, Michael Y., Mandoli, Giulia Elena, Landra, Federico, Chiantini, Benedetta, Bonadiman, Lorenzo, Pastore, Maria Concetta, Focardi, Marta, D’Ascenzi, Flavio, Lisi, Matteo, Diviggiano, Enrico Emilio, Martini, Luca, Bernazzali, Sonia, Valente, Serafina, Maccherini, Massimo, Cameli, Matteo, and Henein, Michael Y.

Abstract

Background: An increasing proportion of heart failure (HF) patients progress to the advanced stage (AdHF) with high event rates and limited treatment options. Echocardiography, particularly Speckle Tracking-derived myocardial work (MW), is useful for HF diagnosis and prognosis. We aimed to assess MW’s feasibility in the prognostic stratification of AdHF. Methods: We retrospectively screened patients with AdHF who accessed our hospital in 2018–2022. We excluded subjects with inadequate acoustic windows; unavailable brachial artery cuff pressure at the time of the echocardiography; atrial fibrillation; and mitral or aortic regurgitation. We measured standard parameters and left ventricular (LV) strain (LS) and MW. The population was followed up to determine the composite outcomes of all-cause mortality, left ventricular assist device implantation and heart transplantation (primary endpoint), as well as unplanned HF hospitalization (secondary endpoint). Results: We enrolled 138 patients, prevalently males (79.7%), with a median age of 58 years (IQR 50–62). AdHF etiology was predominantly non-ischemic (65.9%). Thirty-five patients developed a composite event during a median follow-up of 636 days (IQR 323–868). Diastolic function, pulmonary pressures, and LV GLS and LV MW indices were not associated with major events. Contrarily, for the secondary endpoint, the hazard ratio for each increase in global work index (GWI) by 50 mmHg% was 0.90 (p = 0.025) and for each increase in global constructive work (GCW) by 50 mmHg% was 0.90 (p = 0.022). Kaplan–Meier demonstrated better endpoint-free survival, with an LV GWI ≥ 369 mmHg%. Conclusions: GWI and GCW, with good feasibility, can help in the better characterization of patients with AdHF at higher risk of HF hospitalization and adverse events, identifying the need for closer follow-up or additional HF therapy.

Published
2024
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14. Survival in acute heart failure in intensive cardiac care unit: a prospective study

Author

Sciaccaluga, Carlotta, Mandoli, Giulia Elena, Nannelli, Chiara, Falciani, Francesca, Rizzo, Cosimo, Sisti, Nicolò, Carrucola, Chiara, Vigna, Mariangela, Gioia, Margherita Ilaria, Incampo, Eufemia, Parisella, Maria Luisa, De Vivo, Oreste, Contorni, Francesco, Stricagnoli, Mario, Pagliaro, Antonio, D’Errico, Antonio, Donati, Giovanni, D’Ascenzi, Flavio, Valente, Serafina, Mondillo, Sergio, and Cameli, Matteo

Published
2021
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15. Blood lactate predicts survival after percutaneous implantation of extracorporeal life support for refractory cardiac arrest or cardiogenic shock complicating acute coronary syndrome: insights from the CareGem registry

Author

Porto, Italo, Mattesini, Alessio, D’Amario, Domenico, Sorini Dini, Carlotta, Della Bona, Roberta, Scicchitano, Marco, Vergallo, Rocco, Martellini, Antonio, Caporusso, Simona, Trani, Carlo, Burzotta, Francesco, Bruno, Piergiorgio, Di Mario, Carlo, Crea, Filippo, Valente, Serafina, and Massetti, Massimo

Published
2021
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16. Prognostic Value of APACHE IV Score in Patients Bridged to Heart Transplantation on ECMO.

Author

Lechiancole, Andrea, Russo, Claudio F., Olivieri, Guido M., Maccherini, Massimo, Valente, Serafina, Pacini, Davide, Suarez, Sofia Martin, Boffini, Massimo, Marro, Matteo, Pelenghi, Stefano, Totaro, Pasquale, Isola, Miriam, Martino, Maria De, Bortolotti, Uberto, Livi, Ugolino, and Vendramin, Igor

Subjects
HEART transplant recipients, RECEIVER operating characteristic curves, PROGNOSIS, EXTRACORPOREAL membrane oxygenation, HEART transplantation
Abstract

Background: Methods for risk stratification of candidates for heart transplantation (HTx) supported by extracorporeal membrane oxygenation (ECMO) are limited. We evaluated the reliability of the APACHE IV score to identify the risk of mortality in this patient subset in a multicenter study. Methods: Between January 2010 and December 2022, 167 consecutive ECMO patients were bridged to HTx; they were divided into two groups, according to a cutoff value of APACHE IV score, obtained by receiver operating characteristic curve analysis for 90‐day mortality. Kaplan–Meier survival curves were plotted, and compared through the log‐Rank test. Cox regression model was used to estimate which factors were associated with survival. Results: The 90‐day mortality prediction of the APACHE IV score showed an area under the curve of 0.87 (95% CI: 0.80–0.94), with a cutoff value of 49 (specificity 91.7%–sensibility 69.6%). 125 patients (74.8%) showed an APACHE IV score value < 49 (Group A), and 42 (25.2%) ≥ 49 (Group B). 90‐day mortality was 11.2% in Group A and 76.2% in Group B (p < 0.01). Survival at 1 and 5 years was 85.5%, 77% versus 23.4%, 23.4% (p < 0.01) in Groups A and B. Mortality correlated at univariable analysis with recipient age, body mass index, mechanical ventilation, APACHE IV score, and platelets number. At multivariable analysis only APACHE IV score (HR: 1.07 [1.05–1.09, 95% CI]) independently affected survival. Conclusions: The APACHE IV score represents a powerful predictor of survival in patients bridged to HTx on ECMO support, and could guide candidacy of patients on ECMO. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Left Ventricular Fibrosis as a Main Determinant of Filling Pressures and Left Atrial Function in Advanced Heart Failure

Author

Mandoli, Giulia Elena, primary, Cameli, Matteo, additional, Pastore, Maria Concetta, additional, Loiacono, Ferdinando, additional, Righini, Francesca Maria, additional, D’Ascenzi, Flavio, additional, Focardi, Marta, additional, Cavigli, Luna, additional, Lisi, Matteo, additional, Bisleri, Gianluigi, additional, Dokollari, Aleksander, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, and Henein, Michael, additional

Published
2023
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23. Left ventricular fibrosis as a main determinant of filling pressures and left atrial function in advanced heart failure.

Author

Mandoli, Giulia Elena, Cameli, Matteo, Pastore, Maria Concetta, Loiacono, Ferdinando, Righini, Francesca Maria, D'Ascenzi, Flavio, Focardi, Marta, Cavigli, Luna, Lisi, Matteo, Bisleri, Gianluigi, Dokollari, Aleksander, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, and Henein, Michael Y

Subjects
HEART disease diagnosis, HEART failure risk factors, RISK assessment, BIOPSY, HEART atrium, VENTRICULAR ejection fraction, PULMONARY artery, DESCRIPTIVE statistics, FIBROSIS, CARDIAC output, ELECTROCARDIOGRAPHY, HEART transplantation, COMPARATIVE studies, BLOOD pressure, CONFIDENCE intervals, PATIENT satisfaction, LEFT ventricular dysfunction, HEART ventricles, BIOMARKERS, CARDIAC catheterization, DISEASE complications
Abstract

Aims Advanced heart failure (AdHF) is characterized by variable degrees of left ventricular (LV) dysfunction, myocardial fibrosis, and raised filling pressures which lead to left atrial (LA) dilatation and cavity dysfunction. This study investigated the relationship between LA peak atrial longitudinal strain (PALS), assessed by speckle-tracking echocardiography (STE), and invasive measures of LV filling pressures and fibrosis in a group of AdHF patients undergoing heart transplantation (HTX). Methods and results We consecutively enrolled patients with AdHF who underwent HTX at our Department. Demographic and basic echocardiographic data were registered, then invasive intracardiac pressures were obtained from right heart catheterization, and STE was also performed. After HTX, biopsy specimens from explanted hearts were collected to quantify the degree of LV myocardial fibrosis. Sixty-four patients were included in the study (mean age 62.5 ± 11 years, 42% female). The mean LV ejection fraction (LVEF) was 26.7 ± 6.1%, global PALS was 9.65 ± 4.5%, and mean pulmonary capillary wedge pressure (PCWP) was 18.8 ± 4.8 mmHg. Seventy-three % of patients proved to have severe LV fibrosis. Global PALS was inversely correlated with PCWP (R = −0.83; P < 0.0001) and with LV fibrosis severity (R = −0.78; P < 0.0001) but did not correlate with LVEF (R = 0.15; P = 0.2). Among echocardiographic indices of LV filling pressures, global PALS proved the strongest [area under the curve 0.955 (95% confidence interval 0.87–0.99)] predictor of raised (>18 mmHg) PCWP. Conclusion In patients with AdHF, reduced global PALS strongly correlated with the invasively assessed LV filling pressure and degree of LV fibrosis. Such relationship could be used as non-invasive indicator for optimum patient stratification for therapeutic strategies. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Differences between cardiogenic shock related to acute decompensated heart failure and acute myocardial infarction

Author

Bertaina, Maurizio, primary, Morici, Nuccia, additional, Frea, Simone, additional, Garatti, Laura, additional, Briani, Martina, additional, Sorini, Carlotta, additional, Villanova, Luca, additional, Corrada, Elena, additional, Sacco, Alice, additional, Moltrasio, Marco, additional, Ravera, Amelia, additional, Tedeschi, Michele, additional, Bertoldi, Letizia, additional, Lettino, Maddalena, additional, Saia, Francesco, additional, Corsini, Anna, additional, Camporotondo, Rita, additional, Colombo, Costanza Natalia Julia, additional, Bertolin, Stephanie, additional, Rota, Matteo, additional, Oliva, Fabrizio, additional, Iannaccone, Mario, additional, Valente, Serafina, additional, Pagnesi, Matteo, additional, Metra, Marco, additional, Sionis, Alessandro, additional, Marini, Marco, additional, De Ferrari, Gaetano Maria, additional, Kapur, Navin K., additional, Pappalardo, Federico, additional, and Tavazzi, Guido, additional

Published
2023
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25. Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper

Author

Colivicchi, Furio, Di Fusco, Stefania Angela, Scicchitano, Pietro, Caldarola, Pasquale, Murrone, Adriano, Valente, Serafina, Urbinati, Stefano, Roncon, Loris, Amodeo, Vincenzo, Aspromonte, Nadia, Cipriani, Manlio, Domenicucci, Stefano, Francese, Giuseppina Maura, Imazio, Massimo, Scotto di Uccio, Fortunato, Di Lenarda, Andrea, Gulizia, Michele Massimo, and Gabrielli, Domenico

Published
2021
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26. Tricuspid Regurgitation Velocity and Mean Pressure Gradient for the Prediction of Pulmonary Hypertension According to the New Hemodynamic Definition

Author

Mandoli, Giulia Elena, primary, Landra, Federico, additional, Chiantini, Benedetta, additional, Sciaccaluga, Carlotta, additional, Pastore, Maria Concetta, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, Cameli, Matteo, additional, and Henein, Michael, additional

Published
2023
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27. Right Ventricular Myocardial Work for the Prediction of Early Right Heart Failure and Long-term Mortality After Left Ventricular Assist Device Implant

Author

Landra, Federico, primary, Sciaccaluga, Carlotta, additional, Pastore, Maria Concetta, additional, Gallone, Guglielmo, additional, Barilli, Maria, additional, Fusi, Chiara, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Natali, Benedetta Maria, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, Cameli, Matteo, additional, and Mandoli, Giulia Elena, additional

Published
2023
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28. Heart transplantation and anti‐HLA antibodY: myocardial dysfunction and prognosis ‐ HeartLAy study

Author

Sciaccaluga, Carlotta, primary, Natali, Benedetta Maria, additional, Righini, Francesca Maria, additional, Sorini Dini, Carlotta, additional, Landra, Federico, additional, Mandoli, Giulia Elena, additional, Sisti, Nicolò, additional, Menci, Daniele, additional, D'Errico, Antonio, additional, D'Ascenzi, Flavio, additional, Focardi, Marta, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, and Cameli, Matteo, additional

Published
2023
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29. Pressure–strain loops unveil haemodynamics behind mechanical circulatory support systems

Author

Landra, Federico, primary, Mandoli, Giulia Elena, additional, Sciaccaluga, Carlotta, additional, Gallone, Guglielmo, additional, Bruno, Francesco, additional, Fusi, Chiara, additional, Barilli, Maria, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D'Ascenzi, Flavio, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Cameli, Matteo, additional, and Valente, Serafina, additional

Published
2023
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31. Italian Association of Hospital Cardiologists Position Paper ‘Gender discrepancy: time to implement gender-based clinical management’

Author

Lucà, Fabiana, Pavan, Daniela, Gulizia, Michele Massimo, Manes, Maria Teresa, Abrignani, Maurizio Giuseppe, Benedetto, Francesco Antonio, Bisceglia, Irma, Brigido, Silvana, Caldarola, Pasquale, Calvanese, Raimondo, Canale, Maria Laura, Caretta, Giorgio, Ceravolo, Roberto, Chieffo, Alaide, Chimenti, Cristina, Cornara, Stefano, Cutolo, Ada, Di Fusco, Stefania Angela, Di Matteo, Irene, Di Nora, Concetta, Fattirolli, Francesco, Favilli, Silvia, Francese, Giuseppina Maura, Gelsomino, Sandro, Geraci, Giovanna, Giubilato, Simona, Ingianni, Nadia, Iorio, Annamaria, Lanni, Francesca, Montalto, Andrea, Nardi, Federico, Navazio, Alessandro, Nesti, Martina, Parrini, Iris, Pilleri, Annarita, Pozzi, Andrea, Rao, Carmelo Massimiliano, Riccio, Carmine, Rossini, Roberta, Scicchitano, Pietro, Valente, Serafina, Zuccalà, Giuseppe, Gabrielli, Domenico, Grimaldi, Massimo, Colivicchi, Furio, and Oliva, Fabrizio

Abstract

It has been well assessed that women have been widely under-represented in cardiovascular clinical trials. Moreover, a significant discrepancy in pharmacological and interventional strategies has been reported. Therefore, poor outcomes and more significant mortality have been shown in many diseases. Pharmacokinetic and pharmacodynamic differences in drug metabolism have also been described so that effectiveness could be different according to sex. However, awareness about the gender gap remains too scarce. Consequently, gender-specific guidelines are lacking, and the need for a sex-specific approach has become more evident in the last few years. This paper aims to evaluate different therapeutic approaches to managing the most common women’s diseases.

Published
2024
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34. Right ventricular myocardial work for the prediction of early right heart failure and long-term mortality after left ventricular assist device implant.

Author

Landra, Federico, Sciaccaluga, Carlotta, Pastore, Maria Concetta, Gallone, Guglielmo, Barilli, Maria, Fusi, Chiara, Focardi, Marta, Cavigli, Luna, D'Ascenzi, Flavio, Natali, Benedetta Maria, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, Cameli, Matteo, and Mandoli, Giulia Elena

Subjects
LEFT heart ventricle surgery, MORTALITY risk factors, HEART failure risk factors, ECHOCARDIOGRAPHY, MYOCARDIUM, RIGHT heart ventricle, HEART assist devices, RETROSPECTIVE studies, RISK assessment, HEART physiology, RECEIVER operating characteristic curves, SENSITIVITY & specificity (Statistics)
Abstract

Aims Right heart failure (RHF) after left ventricular assist device (LVAD) implant is burdened by high morbidity and mortality rates and should be prevented by appropriate patient selection. Adequate right ventricular function is of paramount importance but its assessment is complex and cannot disregard afterload. Myocardial work (MW) is a non-invasive Speckle Tracking Echocardiography-derived method to estimate pressure–volume loops. The aim of this study was to evaluate the performance of right ventricular myocardial work to predict RHF and long-term mortality after LVAD implant. Methods and results Consecutive patients from May 2017 to February 2022 undergoing LVAD implant were retrospectively reviewed. Patients without a useful echocardiographic exam prior to LVAD implant were excluded. MW analysis was performed. The primary endpoints were early RHF (<30 days from LVAD implant) and death at latest available follow-up. We included 23 patients (mean age 64 ± 8 years, 91% men). Median follow-up was 339 days (IQR: 30–1143). Early RHF occurred in six patients (26%). A lower right ventricular global work efficiency [RVGWE, OR 0.86, 95% confidence intervals (CI) 0.76–0.97, P = 0.014] was associated with the occurrence of early RHF. Among MW indices, the performance for early RHF prediction was greatest for RVGWE [area under the curve (AUC) 0.92] and a cut-off of 77% had a 100% sensitivity and 82% specificity. At long-term follow-up, death occurred in 4 of 14 patients (28.6%) in the RVGWE > 77% group and in 6 of 9 patients (66.7%) in the RVGWE < 77% group (HR 0.25, 95% CI 0.07–0.90, P = 0.033). Conclusion RVGWE was a predictor of early RHF after LVAD implant and brought prognostic value in terms of long-term mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Epinephrine and short-term survival in cardiogenic shock: an individual data meta-analysis of 2583 patients

Author

Léopold, Valentine, Gayat, Etienne, Pirracchio, Romain, Spinar, Jindrich, Parenica, Jiri, Tarvasmäki, Tuukka, Lassus, Johan, Harjola, Veli-Pekka, Champion, Sébastien, Zannad, Faiez, Valente, Serafina, Urban, Philip, Chua, Horng-Ruey, Bellomo, Rinaldo, Popovic, Batric, Ouweneel, Dagmar M., Henriques, José P. S., Simonis, Gregor, Lévy, Bruno, Kimmoun, Antoine, Gaudard, Philippe, Basir, Mir Babar, Markota, Andrej, Adler, Christoph, Reuter, Hannes, Mebazaa, Alexandre, and Chouihed, Tahar

Published
2018
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37. ADONHERS (Aged DONor HEart Rescue by Stress Echo) National Protocol: Recipient’s Survival after 10-Year Follow-Up

Author

Mandoli, Giulia Elena, primary, Barilli, Maria, additional, Soviero, Davide, additional, Ghionzoli, Nicolò, additional, Landra, Federico, additional, Maccherini, Massimo, additional, Bernazzali, Sonia, additional, Natali, Benedetta Maria, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Pastore, Maria Concetta, additional, Sciaccaluga, Carlotta, additional, Bombardini, Tonino, additional, Valente, Serafina, additional, and Cameli, Matteo, additional

Published
2023
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38. ANMCO position paper on vericiguat use in heart failure: from evidence to place in therapy

Author

Di Fusco, Stefania Angela, primary, Alonzo, Alessandro, additional, Aimo, Alberto, additional, Matteucci, Andrea, additional, Intravaia, Rita Cristina Myriam, additional, Aquilani, Stefano, additional, Cipriani, Manlio, additional, De Luca, Leonardo, additional, Navazio, Alessandro, additional, Valente, Serafina, additional, Gulizia, Michele Massimo, additional, Gabrielli, Domenico, additional, Oliva, Fabrizio, additional, and Colivicchi, Furio, additional

Published
2023
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39. ANMCO position paper on the management of hypercholesterolaemia in patients with acute coronary syndrome

Author

De Luca, Leonardo, primary, Riccio, Carmine, additional, Navazio, Alessandro, additional, Valente, Serafina, additional, Cipriani, Manlio, additional, Corda, Marco, additional, De Nardo, Alfredo, additional, Francese, Giuseppina Maura, additional, Napoletano, Cosimo, additional, Tizzani, Emanuele, additional, Roncon, Loris, additional, Caldarola, Pasquale, additional, Gulizia, Michele Massimo, additional, Gabrielli, Domenico, additional, Oliva, Fabrizio, additional, and Colivicchi, Furio, additional

Published
2023
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40. Tricuspid regurgitation velocity and mean pressure gradient for the prediction of pulmonary hypertension according to the new hemodynamic definition

Author

Mandoli, Giulia Elena, Landra, Federico, Chiantini, Benedetta, Sciaccaluga, Carlotta, Pastore, Maria Concetta, Focardi, Marta, Cavigli, Luna, D’Ascenzi, Flavio, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, Cameli, Matteo, Henein, Michael Y., Mandoli, Giulia Elena, Landra, Federico, Chiantini, Benedetta, Sciaccaluga, Carlotta, Pastore, Maria Concetta, Focardi, Marta, Cavigli, Luna, D’Ascenzi, Flavio, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, Cameli, Matteo, and Henein, Michael Y.

Abstract

Background: The hemodynamic definition of PH has recently been revised with unchanged threshold of peak tricuspid regurgitation velocity (TRV). The aim of this study was to evaluate the predictive accuracy of peak TRV for PH based on the new (>20 mmHg) and the old (>25 mmHg) cut-off value for mean pulmonary artery pressure (mPAP) and to compare it with the mean right ventricular–right atrial (RV–RA) pressure gradient. Methods: Patients with advanced heart failure were screened from 2016 to 2021. The exclusion criteria were absent right heart catheterization (RHC) results, chronic obstructive pulmonary disease, any septal defect, inadequate acoustic window or undetectable TR. The mean RV–RA gradient was calculated from the velocity–time integral of TR. Results: The study included 41 patients; 34 (82.9%) had mPAP > 20 mmHg and 24 (58.5%) had mPAP > 25 mmHg. The AUC for the prediction of PH with mPAP > 20 mmHg was 0.855 for peak TRV and mean RV–RA gradient was 0.811. AUC for the prediction of PH defined as mPAP > 25 mmHg for peak TRV was 0.860 and for mean RV–RA gradient was 0.830. A cutoff value of 2.4 m/s for peak TRV had 65% sensitivity and 100% positive predictive value for predicting PH according to the new definition. Conclusions: Peak TRV performed better than mean RV–RA pressure gradient in predicting PH irrespective of hemodynamic definitions. Peak TRV performed similarly with the two definitions of PH, but a lower cutoff value had higher sensitivity and equal positive predictive value for PH.

Published
2023
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50. A New Integrated Clinical-Biohumoral Model to Predict Functionally Significant Coronary Artery Disease in Patients With Chronic Chest Pain

Author

Caselli, Chiara, Rovai, Daniele, Lorenzoni, Valentina, Carpeggiani, Clara, Teresinska, Anna, Aguade, Santiago, Todiere, Giancarlo, Gimelli, Alessia, Schroeder, Stephen, Casolo, Giancarlo, Poddighe, Rosa, Pugliese, Francesca, Le Guludec, Dominique, Valente, Serafina, Sambuceti, Gianmario, Perrone-Filardi, Pasquale, Del Ry, Silvia, Marinelli, Martina, Nekolla, Stephan, Pietila, Mikko, Lombardi, Massimo, Sicari, Rosa, Scholte, Arthur, Zamorano, José, Kaufmann, Philipp A., Underwood, S. Richard, Knuuti, Juhani, Giannessi, Daniela, and Neglia, Danilo

Published
2015
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