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932 results on '"Vaira, P"'

7. Nodal cluster solutions for the Brezis-Nirenberg problem in dimensions $N\geq 7$

Author

Musso, Monica, Rocci, Serena, and Vaira, Giusi

Subjects
Mathematics - Analysis of PDEs
Abstract

We show that the classical Brezis-Nirenberg problem $$\Delta u + |u|^{4 \over N-2} u + \varepsilon u = 0 ,\quad {\mbox {in}} \quad \Omega, \quad u= 0 , \quad {\mbox {on}} \quad \partial \Omega$$ admits nodal solutions clustering around a point on the boundary of $\Omega$ as $\varepsilon \to 0$, for smooth bounded domains $\Omega \subset \mathbb{R}^N $ in dimensions $N\geq 7$.

Published
2023

8. Partially concentrating standing waves for weakly coupled Schr\'odinger systems

Author

Pellacci, Benedetta, Pistoia, Angela, Vaira, Giusi, and Verzini, Gianmaria

Subjects
Mathematics - Analysis of PDEs
Abstract

We study the existence of standing waves for the following weakly coupled system of two Schr\"odinger equations in $\mathbb{R}^N$, $N=2,3$, \[ \begin{cases} i \hslash \partial_{t}\psi_{1}=-\frac{\hslash^2}{2m_{1}}\Delta \psi_{1}+ {V_1}(x)\psi_{1}-\mu_{1}|\psi_{1}|^{2}\psi_{1}-\beta|\psi_{2}|^{2}\psi_{1} & \\ i \hslash \partial_{t}\psi_{2}=-\frac{\hslash^2}{2m_{2}}\Delta \psi_{2}+ {V_2}(x)\psi_{2}-\mu_{2}|\psi_{2}|^{2}\psi_{2}-\beta|\psi_{1}|^{2}\psi_{2},& \end{cases} \] where $V_1$ and $V_2$ are radial potentials bounded from below. We address the case $m_{1}\sim \hslash^2\to0$, $m_2$ constant, and prove the existence of a standing wave solution with both nontrivial components satisfying a prescribed asymptotic profile. In particular, the second component of such solution exhibits a concentrating behavior, while the first one keeps a quantum nature., Comment: 23 pages

Published
2023

10. Assessing ChatGPT’s theoretical knowledge and prescriptive accuracy in bacterial infections: a comparative study with infectious diseases residents and specialists

Author

De Vito, Andrea, Geremia, Nicholas, Marino, Andrea, Bavaro, Davide Fiore, Caruana, Giorgia, Meschiari, Marianna, Colpani, Agnese, Mazzitelli, Maria, Scaglione, Vincenzo, Venanzi Rullo, Emmanuele, Fiore, Vito, Fois, Marco, Campanella, Edoardo, Pistarà, Eugenia, Faltoni, Matteo, Nunnari, Giuseppe, Cattelan, Annamaria, Mussini, Cristina, Bartoletti, Michele, Vaira, Luigi Angelo, and Madeddu, Giordano

Published
2024
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13. Changes in hospital admissions for facial fractures during and after COVID 19 pandemic: national multicentric epidemiological analysis on 2938 patients

Author

Petrocelli, Marzia, Ruggiero, Federica, Allegri, Davide, Cutrupi, Sebastiano, Baietti, Anna Maria, Salzano, Giovanni, Maglitto, Fabio, Manfuso, Alfonso, Copelli, Chiara, Barca, Ida, Cristofaro, Maria Giulia, Galvano, Francesca, Loche, Valentina Poddi, Gemini, Paolo, Tewfik, Karim, Burlini, Dante, Bernardi, Marco, Bianchi, Francesca Antonella, Catanzaro, Susanna, Ascani, Giuliano, Consorti, Giuseppe, Balercia, Paolo, Braconi, Andrea, Scozzaro, Calogero, Catalfamo, Luciano, De Rinaldis, Danilo, De Ponte, Francesco Saverio, Tarabbia, Filippo, Biglioli, Federico, Giovacchini, Francesco, Tullio, Antonio, Cama, Antonia, Di Emidio, Paolo, Ferrari, Silvano, Perlangeli, Giuseppe, Rossi, Maria Beatrice, Biglio, Andrea, De Riu, Giacomo, Califano, Luigi, and Vaira, Luigi Angelo

Published
2024
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16. Validation of the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool: a new tool to assess the quality of health information provided by AI platforms

Author

Vaira, Luigi Angelo, Lechien, Jerome R., Abbate, Vincenzo, Allevi, Fabiana, Audino, Giovanni, Beltramini, Giada Anna, Bergonzani, Michela, Boscolo-Rizzo, Paolo, Califano, Gianluigi, Cammaroto, Giovanni, Chiesa-Estomba, Carlos M., Committeri, Umberto, Crimi, Salvatore, Curran, Nicholas R., di Bello, Francesco, di Stadio, Arianna, Frosolini, Andrea, Gabriele, Guido, Gengler, Isabelle M., Lonardi, Fabio, Maglitto, Fabio, Mayo-Yáñez, Miguel, Petrocelli, Marzia, Pucci, Resi, Saibene, Alberto Maria, Saponaro, Gianmarco, Tel, Alessandro, Trabalzini, Franco, Trecca, Eleonora M. C., Vellone, Valentino, Salzano, Giovanni, and De Riu, Giacomo

Published
2024
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21. Is generative pre-trained transformer artificial intelligence (Chat-GPT) a reliable tool for guidelines synthesis? A preliminary evaluation for biologic CRSwNP therapy

Author

Maniaci, Antonino, Saibene, Alberto Maria, Calvo-Henriquez, Christian, Vaira, Luigi, Radulesco, Thomas, Michel, Justin, Chiesa-Estomba, Carlos, Sowerby, Leigh, Lobo Duro, David, Mayo-Yanez, Miguel, Maza-Solano, Juan, Lechien, Jerome Rene, La Mantia, Ignazio, and Cocuzza, Salvatore

Published
2024
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31. Positive Blow-up Solutions for a Linearly Perturbed Boundary Yamabe Problem

Author

Cruz-Blázquez, Sergio and Vaira, Giusi

Subjects
Mathematics - Analysis of PDEs, 35B44, 53C21, 58J32
Abstract

We consider the problem of prescribing the scalar and boundary mean curvatures via conformal deformation of the metric on a $n-$ dimensional compact Riemannian manifold. We deal with the case of negative scalar curvature $K$ and boundary mean curvature $H$ of arbitrary sign which are non-constant and $\mathfrak D_n=\sqrt{n(n-1)}{|K|}^{-1/2}>1$ at some point of the boundary. It is known that this problem admits a positive mountain pass solution if $n=3$, while no existence results are known for $n\geq 4$. We will consider a perturbation of the geometric problem and show the existence of a positive solution which blows-up at a boundary point which is critical for both prescribed curvatures., Comment: 15 pages

Published
2023

32. Clustering phenomena in low dimensions for a boundary Yamabe problem

Author

Cruz-Blázquez, Sergio, Pistoia, Angela, and Vaira, Giusi

Subjects
Mathematics - Analysis of PDEs, 35B44, 58J32
Abstract

We consider the classical geometric problem of prescribing the scalar and boundary mean curvatures via conformal deformation of the metric on a $n-$dimensional compact Riemannian manifold. We deal with the case of negative scalar curvature and positive boundary mean curvature. It is known that if $n=3$ all the blow-up points are isolated and simple. In this work we prove that, for a linear perturbation, this is not true anymore in low dimensions $4\leq n\leq 7$. In particular, we construct a solution with a clustering blow-up boundary point (i.e. non-isolated), which is non-umbilic and is a local minimizer of the norm of the trace-free second fundamental form of the boundary., Comment: 55 pages

Published
2022

34. Is Systemic Chemotherapy Useful in Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Colorectal Peritoneal Metastases? A Propensity-Score Analysis

Author

Tonello, Marco, Baratti, Dario, Sammartino, Paolo, Di Giorgio, Andrea, Robella, Manuela, Sassaroli, Cinzia, Framarini, Massimo, Valle, Mario, Macrì, Antonio, Graziosi, Luigina, Coccolini, Federico, Lippolis, Piero Vincenzo, Gelmini, Roberta, Deraco, Marcello, Biacchi, Daniele, Santullo, Francesco, Vaira, Marco, Di Lauro, Katia, D’Acapito, Fabrizio, Carboni, Fabio, Milone, Erica, Donini, Annibale, Fugazzola, Paola, Faviana, Pinuccia, Sorrentino, Lorena, Pizzolato, Elisa, Cenzi, Carola, Del Bianco, Paola, and Sommariva, Antonio

Published
2024
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40. Navigating taxonomic complexity: A use-case report on FAIR scientific name-matching service usage in ENVRI Research Infrastructures

Author

Sharif Islam, Dario Papale, Lucia Vaira, Ilaria Rosati, Johannes Peterseil, and Christian Pichot

Subjects
scientific names, taxonomy, biodiversity, FAIR, EN, Science
Abstract

This paper presents a use-case conducted within the ENVRI FAIR project, examining challenges and opportunities in deploying FAIR-aligned (ensuring Findability, Accessibility, Interoperability and Reusability) scientific name-matching services across Environmental Research Infrastructures (RIs). Six services were tested using various name variations, revealing inconsistencies in match types, status reporting and handling of canonical forms and typos. These diversities pose challenges for RI data pipelines and interoperability. The paper underscores the importance of standardised tools, enhanced communication, training, collaboration and shared resources. Addressing these needs can facilitate more effective FAIR implementation within the ENVRI community and biodiversity research. This, in turn, will empower RIs to seamlessly integrate and leverage scientific names, unlocking the full potential of their data for research and policy implementation.

Published
2024
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41. Twelve-hour normothermic liver perfusion in a rat model: characterization of the changes in the ex-situ bio-molecular phenotype and metabolism

Author

Daniele Dondossola, Caterina Lonati, Michele Battistin, Luigi Vivona, Alberto Zanella, Marco Maggioni, Vaira Valentina, Laimdota Zizmare, Christoph Trautwein, Andrea Schlegel, and Stefano Gatti

Subjects
Medicine, Science
Abstract

Abstract The partial understanding of the biological events that occur during normothermic machine perfusion (NMP) and particularly during prolonged perfusion might hinder its deployment in clinical transplantation. The aim of our study was to implement a rat model of prolonged NMP to characterize the bio-molecular phenotype and metabolism of the perfused organs. Livers (n = 5/group) were procured and underwent 4 h (NMP4h) or 12 h (NMP12h) NMP, respectively, using a perfusion fluid supplemented with an acellular oxygen carrier. Organs that were not exposed to any procedure served as controls (Native). All perfused organs met clinically derived viability criteria at the end of NMP. Factors related to stress-response and survival were increased after prolonged perfusion. No signs of oxidative damage were detected in both NMP groups. Evaluation of metabolite profiles showed preserved mitochondrial function, activation of Cori cycle, induction of lipolysis, acetogenesis and ketogenesis in livers exposed to 12 h-NMP. Increased concentrations of metabolites involved in glycogen synthesis, glucuronidation, bile acid conjugation, and antioxidant response were likewise observed. In conclusion, our NMP12h model was able to sustain liver viability and function, thereby deeply changing cell homeostasis to maintain a newly developed equilibrium. Our findings provide valuable information for the implementation of optimized protocols for prolonged NMP.

Published
2024
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42. Pathophysiological profile of non-ventilated lung injury in healthy female pigs undergoing mechanical ventilation

Author

Elena Spinelli, Anna Damia, Francesco Damarco, Beatrice Gregori, Federica Occhipinti, Zara Busani, Marco Leali, Michele Battistin, Caterina Lonati, Zhanqi Zhao, Alessandra Maria Storaci, Gianluca Lopez, Valentina Vaira, Stefano Ferrero, Lorenzo Rosso, Stefano Gatti, and Tommaso Mauri

Subjects
Medicine
Abstract

Abstract Background Lung regions excluded from mechanical insufflation are traditionally assumed to be spared from ventilation-associated lung injury. However, preliminary data showed activation of potential mechanisms of injury within these non-ventilated regions (e.g., hypoperfusion, inflammation). Methods In the present study, we hypothesized that non-ventilated lung injury (NVLI) may develop within 24 h of unilateral mechanical ventilation in previously healthy pigs, and we performed extended pathophysiological measures to profile NVLI. We included two experimental groups undergoing exclusion of the left lung from the ventilation with two different tidal volumes (15 vs 7.5 ml/kg) and a control group on bilateral ventilation. Pathophysiological alteration including lung collapse, changes in lung perfusion, lung stress and inflammation were measured. Lung injury was quantified by histological score. Results Histological injury score of the non-ventilated lung is significantly higher than normally expanded lung from control animals. The histological score showed lower intermediate values (but still higher than controls) when the tidal volume distending the ventilated lung was reduced by 50%. Main pathophysiological alterations associated with NVLI were: extensive lung collapse; very low pulmonary perfusion; high inspiratory airways pressure; and higher concentrations of acute-phase inflammatory cytokines IL-6, IL-1β and TNF-α and of Angiopoietin-2 (a marker of endothelial activation) in the broncho-alveolar lavage. Only the last two alterations were mitigated by reducing tidal volume, potentially explaining partial protection. Conclusions Non-ventilated lung injury develops within 24 h of controlled mechanical ventilation due to multiple pathophysiological alterations, which are only partially prevented by low tidal volume.

Published
2024
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43. Segregated solutions for some non-linear Schr\'odinger systems with critical growth

Author

Chen, Haixia, Pistoia, Angela, and Vaira, Giusi

Subjects
Mathematics - Analysis of PDEs
Abstract

We find infinitely many positive non-radial solutions for a system of Schr\"odinger equations with critical growth in a fully attractive or repulsive regime in presence of an external radial trapping potential., Comment: 28 pages

Published
2022

48. Phase separating solutions for two component systems in general planar domains

Author

Kowalczyk, Michał, Pistoia, Angela, and Vaira, Giusi

Subjects
Mathematics - Analysis of PDEs
Abstract

In this paper we consider a two component system of coupled non linear Schr\"odinger equations modeling the phase separation in the binary mixture of Bose-Einstein condensates and other related problems. Assuming the existence of solutions in the limit of large interspecies scattering length $\beta$ the system reduces to a couple of scalar problems on subdomains of pure phases. Here we show that given a solution to the limiting problem under some additional non degeneracy assumptions there exists a family of solutions parametrized by the parameter $\beta\gg 1$.

Published
2022

49. Ongoing declines for the world’s amphibians in the face of emerging threats

Author

Luedtke, Jennifer A., Chanson, Janice, Neam, Kelsey, Hobin, Louise, Maciel, Adriano O., Catenazzi, Alessandro, Borzée, Amaël, Hamidy, Amir, Aowphol, Anchalee, Jean, Anderson, Sosa-Bartuano, Ángel, Fong G., Ansel, de Silva, Anslem, Fouquet, Antoine, Angulo, Ariadne, Kidov, Artem A., Muñoz Saravia, Arturo, Diesmos, Arvin C., Tominaga, Atsushi, Shrestha, Biraj, Gratwicke, Brian, Tjaturadi, Burhan, Martínez Rivera, Carlos C., Vásquez Almazán, Carlos R., Señaris, Celsa, Chandramouli, S. R., Strüssmann, Christine, Cortez Fernández, Claudia Fabiola, Azat, Claudio, Hoskin, Conrad J., Hilton-Taylor, Craig, Whyte, Damion L., Gower, David J., Olson, Deanna H., Cisneros-Heredia, Diego F., Santana, Diego José, Nagombi, Elizah, Najafi-Majd, Elnaz, Quah, Evan S. H., Bolaños, Federico, Xie, Feng, Brusquetti, Francisco, Álvarez, Francisco S., Andreone, Franco, Glaw, Frank, Castañeda, Franklin Enrique, Kraus, Fred, Parra-Olea, Gabriela, Chaves, Gerardo, Medina-Rangel, Guido F., González-Durán, Gustavo, Ortega-Andrade, H. Mauricio, Machado, Iberê F., Das, Indraneil, Dias, Iuri Ribeiro, Urbina-Cardona, J. Nicolas, Crnobrnja-Isailović, Jelka, Yang, Jian-Huan, Jianping, Jiang, Wangyal, Jigme Tshelthrim, Rowley, Jodi J. L., Measey, John, Vasudevan, Karthikeyan, Chan, Kin Onn, Gururaja, Kotambylu Vasudeva, Ovaska, Kristiina, Warr, Lauren C., Canseco-Márquez, Luis, Toledo, Luís Felipe, Díaz, Luis M., Khan, M. Monirul H., Meegaskumbura, Madhava, Acevedo, Manuel E., Napoli, Marcelo Felgueiras, Ponce, Marcos A., Vaira, Marcos, Lampo, Margarita, Yánez-Muñoz, Mario H., Scherz, Mark D., Rödel, Mark-Oliver, Matsui, Masafumi, Fildor, Maxon, Kusrini, Mirza D., Ahmed, Mohammad Firoz, Rais, Muhammad, Kouamé, N’Goran G., García, Nieves, Gonwouo, Nono Legrand, Burrowes, Patricia A., Imbun, Paul Y., Wagner, Philipp, Kok, Philippe J. R., Joglar, Rafael L., Auguste, Renoir J., Brandão, Reuber Albuquerque, Ibáñez, Roberto, von May, Rudolf, Hedges, S. Blair, Biju, S. D., Ganesh, S. R., Wren, Sally, Das, Sandeep, Flechas, Sandra V., Ashpole, Sara L., Robleto-Hernández, Silvia J., Loader, Simon P., Incháustegui, Sixto J., Garg, Sonali, Phimmachak, Somphouthone, Richards, Stephen J., Slimani, Tahar, Osborne-Naikatini, Tamara, Abreu-Jardim, Tatianne P. F., Condez, Thais H., De Carvalho, Thiago R., Cutajar, Timothy P., Pierson, Todd W., Nguyen, Truong Q., Kaya, Uğur, Yuan, Zhiyong, Long, Barney, Langhammer, Penny, and Stuart, Simon N.

Published
2023
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