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9 results on '"Vail MH"'

1. Use of enzyme-deficient cell culture lines as a biochemical screen for study of purines, purine nucleosides and related compounds.

Author

Bennett LL Jr, Vail MH, Allan PW, and Shaddix SC

Subjects
Adenine Nucleotides, Carbon Isotopes, Carcinoma, Squamous Cell enzymology, Cell Line, Cells, Cultured, Drug Resistance, Guanine Nucleotides, Humans, Hypoxanthines, Mercaptopurine pharmacology, Purine Nucleotides, Sulfur Isotopes, Pentosyltransferases metabolism, Phosphotransferases metabolism, Purine-Pyrimidine Metabolism, Inborn Errors
Published
1973
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4. Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and some chemically related compounds upon the progression of cultured H.Ep. no. 2 cells through the cell cycle.

Author

Wheeler GP, Bowdon BJ, Adamson DJ, and Vail MH

Subjects
Animals, Benzocycloheptenes pharmacology, Carcinoma, Cell Line, Cyanates pharmacology, Ethylamines pharmacology, Humans, Laryngeal Neoplasms, Leukemia L1210, Nitrogen Mustard Compounds pharmacology, Thymidine metabolism, Cell Division drug effects, Culture Techniques, Nitroso Compounds pharmacology, Urea pharmacology
Published
1970

5. Studies with 8-azainosine, a cytotoxic nucleoside with antitumor activity.

Author

Bennett LL Jr, Vail MH, Allan PW, and Laster WR Jr

Subjects
Adenocarcinoma drug therapy, Adenocarcinoma enzymology, Animals, Aza Compounds antagonists & inhibitors, Aza Compounds pharmacology, Aza Compounds therapeutic use, Azaguanine pharmacology, Carcinoma, Squamous Cell drug therapy, Carcinoma, Squamous Cell enzymology, Cell Line, Cells, Cultured, Drug Resistance, Humans, Hypoxanthines pharmacology, Imidazoles pharmacology, Inosine antagonists & inhibitors, Leukemia L1210 drug therapy, Mercaptopurine pharmacology, Mice, Mice, Inbred Strains, Neoplasms, Experimental, Pentosyltransferases metabolism, Phosphotransferases metabolism, Purines metabolism, Antineoplastic Agents pharmacology, Antineoplastic Agents therapeutic use, Inosine pharmacology, Inosine therapeutic use
Published
1973

7. Resistance to 4-aminopyrazolo (3,4-d) pyrimidine.

Author

Bennett LL Jr, Allan PW, Smithers D, and Vail MH

Subjects
Adenine metabolism, Carbon Isotopes, Cell Membrane Permeability, Chromatography, Clone Cells enzymology, Humans, Nucleosides metabolism, Nucleosides pharmacology, Phosphotransferases pharmacology, Purines biosynthesis, Purines pharmacology, Pyrimidines analysis, Pyrimidines metabolism, Clone Cells growth & development, Purines metabolism, Pyrimidines pharmacology
Published
1969
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8. Effects of certain nitrogen mustards upon the progression of cultured H.Ep. no. 2 cells through the cell cycle.

Author

Wheeler GP, Bowdon BJ, Adamson DJ, and Vail MH

Subjects
Benzocycloheptenes pharmacology, Carcinoma, Cell Line, Cell Nucleus metabolism, DNA metabolism, Humans, Laryngeal Neoplasms, Mechlorethamine pharmacology, Mechlorethamine toxicity, Nitrogen Mustard Compounds toxicity, Thymidine metabolism, Tritium, Culture Techniques, Mitosis drug effects, Nitrogen Mustard Compounds pharmacology
Published
1970

9. Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.

Author

Wheeler GP, Bowdon BJ, Adamson DJ, and Vail MH

Subjects
Antimetabolites administration & dosage, Azaguanine pharmacology, Carcinoma drug therapy, Cell Line, Cell Survival, Cytarabine pharmacology, DNA Replication drug effects, Dose-Response Relationship, Drug, Floxuridine pharmacology, Fluorouracil pharmacology, Humans, Hydroxyurea pharmacology, Laryngeal Neoplasms drug therapy, Mercaptopurine pharmacology, Methotrexate pharmacology, Mitosis drug effects, Ribonucleosides pharmacology, Thioguanine pharmacology, Time Factors, Tritium, Antimetabolites pharmacology, Cell Division drug effects
Published
1972

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