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2. Factors associated with prior completion of colorectal cancer and hepatitis C virus screenings among community health center patients: a cross-sectional study to inform a multi-behavioral educational intervention

Author

Gutstein, Lila, Arevalo, Mariana, Reich, Richard R., Fan, Wenyi, Vadaparampil, Susan T., Meade, Cathy D., Abdulla, Rania, Lawrence, Elizabeth, Roetzheim, Richard G., Lopez, Diana, Collier, Aaron, Deak, Emalyn, Ewing, Aldenise P., Gwede, Clement K., and Christy, Shannon M.

Published
2024
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26. Affect regulation as a moderator of intentions for breast cancer chemoprevention

Author

Conley, Claire C., Agnese, Doreen M., Vadaparampil, Susan T., O'Neill, Suzanne C., and Andersen, Barbara L.

Subjects
Women -- Health aspects, Breast cancer -- Care and treatment -- Psychological aspects -- Prevention, Affect (Psychology) -- Health aspects, Chemoprevention -- Psychological aspects -- Methods, Psychology and mental health
Abstract

Women at high risk for breast cancer (BC) may consider chemoprevention for risk reduction, but uptake is low. This study examined the role of affect regulation (the attempt to alter or control one's emotions) in decision-making about BC chemoprevention. A cross-sectional, single group design was used. High-risk women (N = 81) were surveyed. Moderation analyses specified cancer-specific distress as the independent variable, affect regulation (cognitive reappraisal or expressive suppression) as the moderator, and chemoprevention intentions (yes = 1, unsure = 0, no = -1) as the dependent variable. Cognitive reappraisal significantly moderated the relationship between cancer-specific distress and chemoprevention intentions (p = 0.03), but expressive suppression did not (p = 0.31). For the 44% of participants who were highest on reappraisal, higher cancer-specific distress was associated with greater intentions for chemoprevention. For the remaining 56%, there was no relationship between cancer-specific distress and chemoprevention intentions. Cognitive reappraisal may play an important role in decisions regarding uptake of chemoprevention., Author(s): Claire C. Conley [sup.1] [sup.3] , Doreen M. Agnese [sup.1] , Susan T. Vadaparampil [sup.2] , Suzanne C. O'Neill [sup.3] , Barbara L. Andersen [sup.1] Author Affiliations: (1) grid.261331.4, [...]

Published
2022
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30. The National Physicians Cooperative: transforming fertility management in the cancer setting and beyond

Author

Smith, Brigid M, Duncan, Francesca E, Ataman, Lauren, Smith, Kristin, Quinn, Gwendolyn P, Chang, R Jeffrey, Finlayson, Courtney, Orwig, Kyle, Valli-Pulaski, Hanna, Moravek, Molly B, Zelinski, Mary B, Su, H Irene, Vitek, Wendy, Smith, James F, Jeruss, Jacqueline S, Gracia, Clarisa, Coutifaris, Christos, Shah, Divya, Nahata, Leena, Gomez-Lobo, Veronica, Appiah, Leslie Coker, Brannigan, Robert E, Gillis, Valerie, Gradishar, William, Javed, Asma, Rhoton-Vlasak, Alice S, Kondapalli, Laxmi A, Neuber, Evelyn, Ginsberg, Jill P, Muller, Charles H, Hirshfeld-Cytron, Jennifer, Kutteh, William H, Lindheim, Steven R, Cherven, Brooke, Meacham, Lillian R, Rao, Pooja, Torno, Lilibeth, Sender, Leonard S, Vadaparampil, Susan T, Skiles, Jodi L, Schafer-Kalkhoff, Tara, Frias, Oliva J, Byrne, Julia, Westphal, Lynn M, Schust, Danny J, Klosky, James L, McCracken, Kate A, Ting, Alison, Khan, Zaraq, Granberg, Candace, Lockart, Barbara, Scoccia, Bert, Laronda, Monica M, Mersereau, Jennifer E, Marsh, Courtney, Pavone, Mary Ellen, and Woodruff, Teresa K

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Contraception/Reproduction, Cancer, Prevention, Reproductive health and childbirth, Good Health and Well Being, Adult, Antineoplastic Agents, Behavioral Medicine, Child, Disease Progression, Endocrinology, Female, Fertility, Fertility Preservation, Gynecology, Humans, Intersectoral Collaboration, Medical Oncology, Neoplasms, Obstetrics, Physicians, Practice Guidelines as Topic, Pregnancy, Quality of Life, United States, Urology, fertility preservation, oncofertility, reproductive health, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Once unimaginable, fertility management is now a nationally established part of cancer care in institutions, from academic centers to community hospitals to private practices. Over the last two decades, advances in medicine and reproductive science have made it possible for men, women and children to be connected with an oncofertility specialist or offered fertility preservation soon after a cancer diagnosis. The Oncofertility Consortium's National Physicians Cooperative is a large-scale effort to engage physicians across disciplines - oncology, urology, obstetrics and gynecology, reproductive endocrinology, and behavioral health - in clinical and research activities to enable significant progress in providing fertility preservation options to children and adults. Here, we review the structure and function of the National Physicians Cooperative and identify next steps.

Published
2018

38. Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers.

Author

Kim, Shana J, Huzarski, Tomasz, Gronwald, Jacek, Singer, Christian F, Møller, Pål, Lynch, Henry T, Armel, Susan, Karlan, Beth Y, Foulkes, William D, Neuhausen, Susan L, Senter, Leigha, Eisen, Andrea, Eng, Charis, Panchal, Seema, Pal, Tuya, Olopade, Olufunmilayo, Zakalik, Dana, Lubinski, Jan, Narod, Steven A, Kotsopoulos, Joanne, Ainsworth, Peter, Bordeleau, Louise, Tung, Nadine, Friedman, Eitan, Meschino, Wendy, Snyder, Carrie, Metcalfe, Kelly, Warner, Ellen, Rosen, Barry, Demsky, Rochelle, Weitzel, Jeffrey N, Panabaker, Karen, Couch, Fergus, Manoukian, Siranoush, Pasini, Barbara, Daly, Mary B, Steele, Linda, Saal, Howard, Fallen, Taya, Wood, Marie, McKinnon, Wendy, Lemire, Edmond, Chudley, Albert E, Serfas, Kim, Elser, Christine, Vadaparampil, Susan T, Ginsburg, Ophira, Cullinane, Carey A, Blum, Joanne L, Ross, Theodora, Mauer, Caitlin, Kwong, Ava, Cybulski, Cezary, McCuaig, Jeanna, Rayson, Daniel, and Isaacs, Claudine

Subjects
Cancer, Aging, Nutrition, Prevention, Breast Cancer, Obesity, Clinical Research, Aetiology, 2.2 Factors relating to the physical environment, BMI, body size, breast cancer, BRCA, hereditary cancer, Hereditary Breast Cancer Clinical Study Group, Statistics, Public Health and Health Services, Epidemiology
Abstract

BACKGROUND:Although evidence suggests that larger body size in early life confers lifelong protection from developing breast cancer, few studies have investigated the relationship between body size and breast cancer risk among BRCA mutation carriers. Therefore, we conducted a prospective evaluation of body size and the risk of breast cancer among BRCA mutation carriers. METHODS:Current height and body mass index (BMI) at age 18 were determined from baseline questionnaires. Current BMI and weight change since age 18 were calculated from updated biennial follow-up questionnaires. Cox proportional hazards models were used to estimate the hazard ratio (HR) and 95% confidence interval (CI). RESULTS:Among 3734 BRCA mutation carriers, there were 338 incident breast cancers over a mean follow-up of 5.5 years. There was no association between height, current BMI or weight change and breast cancer risk. Women with BMI at age 18 ≥22.1 kg/m2 had a decreased risk of developing post-menopausal breast cancer compared with women with a BMI at age 18 between 18.8 and 20.3 kg/m2 (HR 0.49; 95% CI 0.30-0.82; P = 0.006). BMI at age 18 was not associated with risk of pre-menopausal breast cancer. CONCLUSIONS:There was no observed association between height, current BMI and weight change and risk of breast cancer. The inverse relationship between greater BMI at age 18 and post-menopausal breast cancer further supports a role of early rather than current or adulthood exposures for BRCA-associated breast cancer development. Future studies with longer follow-up and additional measures of adiposity are necessary to confirm these findings.

Published
2018

46. Health-related quality of life in Black breast cancer survivors with and without triple-negative breast cancer (TNBC)

Author

Vadaparampil, Susan T, Christie, Juliette, Donovan, Kristine A, Kim, Jongphil, Augusto, Bianca, Kasting, Monica L, Holt, Cheryl L, Ashing, Kimlin, Halbert, Chanita Hughes, and Pal, Tuya

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Behavioral and Social Science, Clinical Research, Cancer, Breast Cancer, Adult, Black or African American, Cancer Survivors, Female, Humans, Middle Aged, Quality of Life, Triple Negative Breast Neoplasms, United States, Black women, Breast cancer, Quality of life, Triple-negative breast cancer, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis
Abstract

PurposeBlack women are more likely to develop early-onset (≤50 years) breast cancer (BC) and have the lowest five-year, cause-specific survival rate of any United States (U.S.) racial or ethnic group. These disparities can be attributed partially to the higher rate of triple-negative BC (TNBC) in Blacks. Yet, little is known about health-related quality of life (HRQOL) among Black women with TNBC.MethodsBlack women with invasive BC ≤ 50 years were recruited via the Florida Cancer Data System as part of a population-based case-only study of etiology and outcomes of early-onset invasive BC. Of 460 consented participants, a subset of 355 self-reported sociodemographic, clinical, and psychosocial variables. Descriptive analyses included participants with known TNBC (n = 85) or non-TNBC (n = 245) disease. Univariable and multivariable analyses were conducted to examine differences in factors associated with HRQOL.ResultsIn unadjusted analyses, TNBC participants had significantly lower FACT-B total scores (90.1 ± 27.9) compared to non-TNBC (98.5 ± 27.6) participants (p

Published
2017

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