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Objective: To prospectively compare full dose gadopentetate dimeglumine (Gd-DTPA) with full dose gadobenate dimeglumine (Gd-BOPTA) in the detection of focal hepatic lesions in patients with chronic liver disease on MRI. Materials and Methods: Eight patients with hepatic cirrhosis and a strong suspicion for small hepatocellular carcinoma based on prior MRI underwent contrast-enhanced MR examinations, one with full dose Gd-DTPA and one with full dose Gd-BOPTA. The exams were performed from 72–108 hours apart. Two blinded and independent radiologists evaluated images for lesion number, characterization, enhancement, and subjective preference. Results: There was no statistically significant difference between the two studies for lesion detection or characterization. There was 18% increased lesion enhancement for Gd-BOPTA, compared to Gd-DTPA, of the dominant lesion. Both blinded readers subjectively preferred the images using Gd-BOPTA over Gd-DTPA in the majority of cases, based on greater lesion enhancement and better edge definition. Conclusion: At equivalent full doses, Gd-BOPTA compared similarly with Gd-DTPA in the detection and characterization of focal hepatic lesions in patients with chronic liver disease. However, Gd-BOPTA was superior for increased lesion enhancement and subjective preference of the reader. [ABSTRACT FROM AUTHOR]

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Screening sinus computed tomography (SCCT) of 133 patients performed from March 2003 to February 2004, were retrospectively reviewed, concerning anatomic variation at ostiomeatal unit (OMU) and nasal septal deviation. Six patterns of inflammatory sinus disease were designated: maxillary infundibulum, nasofrontal duct, OMU, sphenoethmoidal recess, polyposis and sporadic. The most common anatomic variation was concha bullosa (14.3%), followed by Haller cell (9.4%), large Agger nasi cell (7.9%) and paradoxical middle turbinate (5.3%). Nasal septal deviation was presented in 75 patients (56.4%). Inflammatory sinus disease was presented in 181 lateral nasal walls (68%) and maxillary infundibular pattern was the most common (33.1%). There was significant correlation between large Agger nasi cell and nasofrontal duct pattern (p < 0.05). The remaining anatomic variations and nasal septal deviation had no significant correlation to the inflammatory sinus disease. Overall, the anatomic variation which can compromise the mucociliary drainage was frequently observed, however, only the large Agger nasi cell had significant correlation to the inflammatory sinus disease.