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141 results on '"Vachhani, Dipak D."'

44. Diversely Substituted Indoloazepinones and Indoloazocinones: A Post-Ugi Gold-Catalyzed Regioselective Carbocyclization Approach.

Author

Vachhani, Dipak D., Kumar, Amit, Modha, Sachin G., Sharma, Sunil K., Parmar, Virinder S., and Van der Eycken, Erik V.

Subjects
*AZEPINONES, *INDOLE derivatives, *SUBSTITUTION reactions, *GOLD catalysts, *REGIOSELECTIVITY (Chemistry), *RING formation (Chemistry), *AZO compounds
Abstract

A post-Ugi gold-catalyzed regioselective intramolecular carbocyclization strategy is reported. A better cationic gold system, compared to our previous report, has been optimized and utilized. The method presented exhibits excellent functional group compatibility including bulky substitutions on alkynes and allows the direct access to indoloazepinones and indoloazocinones in good to excellent yields. [ABSTRACT FROM AUTHOR]

Published
2015
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46. Post Ugi Gold(I)- and Platinum(II)-Catalyzed Alkyne Activation: Synthesis of Diversely Substituted Fused Azepinones and Pyridinones.

Author

Kumar, Amit, Vachhani, Dipak D., Modha, Sachin G., Sharma, Sunil K., Parmar, Virinder S., and Van der Eycken, Erik V.

Subjects
*ARYLATION, *PYRIDONE synthesis, *AZEPINONES, *AZEPINES, *HETEROCYCLIC compounds synthesis, *INDOLE, *CHEMICAL reactions
Abstract

A post-Ugi late-transition-metal-catalyzed intramolecular hydroarylation approach opens a new gateway for the synthesis of diversely substituted pyrrolopyridinones, pyrroloazepinones thiophenoazepinones, azepinoindoles, and azepinobenzothiophenes applying mild reaction conditions. A detailed investigation of the scope of this strategy is discussed. [ABSTRACT FROM AUTHOR]

Published
2013
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47. Diversely Substituted Imidazo[1,2- a]pyrazine-8-oxo-3-carbaldehydes: An Iodine-Mediated Cyclization/Oxidation Approach.

Author

Mishra, Nigam M., Vachhani, Dipak D., Modha, Sachin G., and Van der Eycken, Erik V.

Abstract

A mild and efficient iodine-mediated intramolecular heteroannulation approach for the construction of the imidazo[1,2- a]pyrazinone core has been developed. Under ambient conditions, this metal-free protocol allows easy access to densely functionalized imidazo[1,2- a]pyrazinone-3-carbaldehydes or (aminomethyl)imidazo[1,2- a]pyrazinones from substrates containing terminal alkynes by cyclization and subsequent oxidation or amination. Further diversification may be introduced by using substrates containing an internal alkyne and/or Suzuki coupling after cyclization to generate polysubstituted (dihydro)imidazo[1,2- a]pyrazinones. [ABSTRACT FROM AUTHOR]

Published
2013
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49. Synthesis of (spiro)cyclopentapyridinones via Csp3–H functionalization: a post-Ugi gold-catalyzed regioselective tandem cyclization.

Author

Vachhani, Dipak D., Galli, Marzia, Jacobs, Jeroen, Van Meervelt, Luc, and Van der Eycken, Erik V.

Subjects
*RING formation (Chemistry), *REGIOSELECTIVITY (Chemistry), *TRANSITION metals, *PYRIDONE, *CHEMICALS
Abstract

A gold-catalyzed regioselective tandem cyclization of N-propynylbutynamide via Csp3–H functionalization has been described, providing a distinctive methodology for the architecture of cyclopentapyridinones as well as spirocyclopentapyridinones. [ABSTRACT FROM AUTHOR]

Published
2013
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50. ChemInform Abstract: Solvent Switchable Cycloaddition: A (One-Pot) Metal-Free Approach Towards N-Substituted Benzo[e]- or [f]Isoindolones via C(sp2)-H Functionalization.

Author

Ambasana, Pratik A., Vachhani, Dipak D., Galli, Marzia, Jacobs, Jeroen, Van Meervelt, Luc, Shah, Anamik K., and Van der Eycken, Erik V.

Subjects
*CHEMICAL equations, *RING formation (Chemistry), *SUBSTITUTION reactions
Abstract

The article presents chemical equations related to the article "A (One-Pot) Metal-Free Approach Towards N-Substituted Benzo[e]- or [f]Isoindolones via C(sp²)-H Functionalization" by P. A. Ambasana and others, published in a 2014 issue of the periodical "Organic & Biomolecular Chemistry".

Published
2015
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