7 results on '"V.L.M. Esnault"'
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2. Influence of Immunoadsorption on the Removal of Immunoglobulin G Autoantibodies in Crescentic Glomerulonephritis
- Author
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V.L.M. Esnault, Angelo Testa, J. Guenel, J.-P. Soulillou, and D.R.W. Jayne
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Adult ,Male ,Vasculitis ,Extracorporeal Circulation ,Systemic disease ,Adolescent ,Renal glomerulus ,urologic and male genital diseases ,Anti-Glomerular Basement Membrane Disease ,Antibodies ,Glomerulonephritis ,medicine ,Humans ,Lupus Erythematosus, Systemic ,Staphylococcal Protein A ,Immunoadsorption ,Immunosorbent Techniques ,Autoantibodies ,Lupus erythematosus ,Plasma Exchange ,business.industry ,Middle Aged ,medicine.disease ,Immunoglobulin G ,Immunology ,Female ,Kidney Diseases ,business ,Systemic vasculitis - Abstract
We report the treatment of 5 patients with crescentic glomerulonephritis by immunoadsorption using a protein A column. Two had systemic vasculitis, 2 antiglomerular basement membrane disease and 1 systemic lupus erythematosus (SLE). In the patients with systemic vasculitis and SLE, there was successful removal of autoantibodies and rapid control of disease; remission was maintained over a mean follow-up of 2 years. Clinical improvement was not seen in 2 patients with anti-glomerular basement membrane (GBM) disease who presented with dialysis-dependent renal failure. There were no apparent clinical side-effects related to the immunoadsorption procedure. Protein A immunoadsorption offers a semiselective alternative to plasma exchange and appears to be safe and efficient in removing pathogenic autoantibodies in crescentic glomerulonephritis without anti-GBM antibodies.
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- 1993
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- View/download PDF
3. Contents, Vol. 58, 1991
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Z.H. Endre, Lawrence S. Milner, F. Lemercier, Susanne Horner, Yuji Nagura, P. Saiag, Kazuro Kanatsu, G.A. Balderson, Nachman Brautbar, Takahiko Ono, Franz Fazekas, Atul T. Roy, M.C. de Vernejoul, Tateki Kitaoka, Ove Noren, Geoffrey H. Cope, Xi-Xiong Kang, Michèle Kessler, Batya Kristal, S.L. Lynch, Toshio Doi, Wolfgang Freidl, M.H. Gault, D.H.G. Crawford, Hans Sjöström, M. Potiron-Josse, Masami Kozaki, R. Korte, Jörg H. Horina, Chika Onoe, Yasuhiko Ito, H. Longerich, Kazutomo Ujiie, Mark T. Houser, J.D. Ginet, Helmut Pogglitsch, Nicholas D. Slater, O. Jovanović, A. Quoidbach, Masaharu Yoshida, S.J. Fleming, C.G.H. Maidment, P.C.K. Chan, H. Demol, I. Lubrich-Birkner, H.B. Steinhauer, Monique Elseviers, Luiz C. Cintra, Tamar Shkolnik, M. Kostić, Marc E. De Broe, P. Schollmeyer, Frank L. Van de Vyver, Paulo Sérgio Medeiros dos Santos, Y. Pirson, Takashi Suzuki, Guy D. Nuyts, Eri Muso, Norio Kaji, L. Longerich, Tadao Akizawa, Kazuyoshi Okada, Hiroyuki Nagai, Franz Payer, Osnat Steinberger, K.W. Chan, Atsushi Fukatsu, Hanns M. Winkler, Ronny A. Daelemans, Michinobu Hatano, D. Le Carrer, P. Galle, P. Bindi, Hirofumi Tamai, Tohru Tamaki, Kazuhiro Nishikawa, Bruno Hurault de Ligny, Wahei Matsukawa, Patrick C. D'Haese, Ab. Akosa, Guenter J. Krejs, Heinz Valetitsch, T.M. Chan, Andrew T. Raftery, Niembro De Rasche, M.A. Rengel, Mamoru Maejima, Chuichi Kawai, R. Khayat, Martin Magnusson, Anna Galar, Eriko Kinugasa, B. Winterberg, Uri Shasha, Roberto Silva Costa, Shaul M. Shasha, Etsuo Sakurai, Michael Slater, P. Gris, Futoshi Yoshida, Gomez Campdera, Tatsuto Kimachi, M. Popović-Rolović, Akira Owada, Torsten Denneberg, Nils-Georg Asp, Marie C. Béné, Kimio Tomita, H.P. Bertram, Noriaki Matsui, Hidekazu Shigematsu, Agenor Spallini Ferraz, Gilbert C. Faure, Shozo Koshikawa, Tadao Tamura, Sverker Eneström, J.-P. Vaerman, Maria Walczuk, Stanislaw Jankowski, David B. N. Lee, V.L.M. Esnault, D. Popović, Toshihiko Hirano, Philippe G. Jorens, F. Anaya, Susumu Takahashi, A. Testa, Kryspina Grzybek-Hryncewicz, Satoshi Sekiyama, Haruyoshi Yoshida, Mitsuru Yanai, A. Antić-Peco, Seiichi Matsuo, J. Hamels, Miriam Barzilai, B. Viron, I.K.P. Cheng, Fumiaki Marumo, Vanda Jorgetti, Márcio Dantas, F. Valderrabano, R.A. Axelsen, J. Guenel, Kitaro Oka, A. Galan, A. Sherif, Kenichi Sekita, I. Keck, Kurt Niederkorn, and N.R. Robles
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Traditional medicine ,business.industry ,Medicine ,business - Published
- 1991
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4. Renoprotective properties of angiotensin-converting enzyme inhibitors: proofs and limits?
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V.L.M. Esnault
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biology ,business.industry ,biology.protein ,Medicine ,Humans ,Kidney Failure, Chronic ,Angiotensin-converting enzyme ,Angiotensin-Converting Enzyme Inhibitors ,Blood Pressure ,Kidney Diseases ,Pharmacology ,business ,Antihypertensive Agents - Published
- 2000
5. Major muscle calcifications of the neck after non-traumatic rhabdomyolysis with acute renal failure
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B Dupas, A Testa, V.L.M. Esnault, and J Guenel
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Male ,Pathology ,medicine.medical_specialty ,Radiography ,Rhabdomyolysis ,Muscular Diseases ,Calcinosis ,Non traumatic ,Medicine ,Humans ,Transplantation ,business.industry ,Acute kidney injury ,Myositis ossificans ,Acute Kidney Injury ,Middle Aged ,medicine.disease ,Alcoholism ,Nephrology ,business ,Complication ,Neck ,Calcification - Abstract
We report a case in which lesions were limited to muscle of the neck, simulating a meningeal syndrome, with large calcifications visible on radiography, 99 Tc phosphate scanning, and CT scanning
- Published
- 1990
6. Subject Index, Vol. 58, 1991
- Author
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M.C. de Vernejoul, S.J. Fleming, Eriko Kinugasa, J.-P. Vaerman, Franz Fazekas, Susanne Horner, Tateki Kitaoka, Yuji Nagura, J. Hamels, Franz Payer, M.A. Rengel, Xi-Xiong Kang, Roberto Silva Costa, Atul T. Roy, Miriam Barzilai, Kazuhiro Nishikawa, Atsushi Fukatsu, T.M. Chan, Hanns M. Winkler, Fumiaki Marumo, M. Popović-Rolović, Hiroyuki Nagai, David B. N. Lee, B. Winterberg, Vanda Jorgetti, Osnat Steinberger, Márcio Dantas, Lawrence S. Milner, Hidekazu Shigematsu, G.A. Balderson, A. Quoidbach, D. Popović, Gomez Campdera, F. Valderrabano, A. Sherif, F. Lemercier, Norio Kaji, Z.H. Endre, Tatsuto Kimachi, Kazutomo Ujiie, Helmut Pogglitsch, Michinobu Hatano, R. Korte, P. Bindi, Kazuro Kanatsu, K.W. Chan, Bruno Hurault de Ligny, Toshihiko Hirano, Chika Onoe, Yasuhiko Ito, J. Guenel, Tadao Tamura, Sverker Eneström, Nachman Brautbar, Philippe G. Jorens, Maria Walczuk, Monique Elseviers, Wahei Matsukawa, C.G.H. Maidment, A. Galan, O. Jovanović, Hans Sjöström, P. Schollmeyer, Tohru Tamaki, A. Antić-Peco, Tadao Akizawa, Kazuyoshi Okada, Paulo Sérgio Medeiros dos Santos, Kitaro Oka, Guy D. Nuyts, Eri Muso, Mamoru Maejima, M. Potiron-Josse, H. Demol, Gilbert C. Faure, Chuichi Kawai, Uri Shasha, Haruyoshi Yoshida, Takahiko Ono, Kryspina Grzybek-Hryncewicz, Marc E. De Broe, D. Le Carrer, I. Keck, Torsten Denneberg, Geoffrey H. Cope, Masami Kozaki, Kurt Niederkorn, F. Anaya, Shozo Koshikawa, Nils-Georg Asp, Marie C. Béné, Martin Magnusson, Anna Galar, Susumu Takahashi, A. Testa, Kimio Tomita, Etsuo Sakurai, Mitsuru Yanai, Niembro De Rasche, N.R. Robles, Kenichi Sekita, R. Khayat, Shaul M. Shasha, Futoshi Yoshida, H. Longerich, Takashi Suzuki, Stanislaw Jankowski, V.L.M. Esnault, B. Viron, I.K.P. Cheng, P. Saiag, R.A. Axelsen, Ronny A. Daelemans, S.L. Lynch, D.H.G. Crawford, Mark T. Houser, Patrick C. D'Haese, H.B. Steinhauer, Michèle Kessler, Andrew T. Raftery, Luiz C. Cintra, Tamar Shkolnik, Y. Pirson, Jörg H. Horina, Satoshi Sekiyama, Batya Kristal, Nicholas D. Slater, Toshio Doi, Wolfgang Freidl, M.H. Gault, Masaharu Yoshida, Heinz Valetitsch, P.C.K. Chan, J.D. Ginet, M. Kostić, Frank L. Van de Vyver, Ove Noren, L. Longerich, I. Lubrich-Birkner, P. Galle, Hirofumi Tamai, Ab. Akosa, Guenter J. Krejs, Michael Slater, P. Gris, Akira Owada, H.P. Bertram, Noriaki Matsui, Agenor Spallini Ferraz, and Seiichi Matsuo
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Index (economics) ,business.industry ,Statistics ,Medicine ,Subject (documents) ,business - Published
- 1991
- Full Text
- View/download PDF
7. Captopril but not acebutolol, prazosin or indomethacin decreases postexercise proteinuria
- Author
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J.D. Ginet, M. Potiron-Josse, J. Guenel, V.L.M. Esnault, D. Le Carrer, and A. Testa
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Adult ,medicine.medical_specialty ,Captopril ,Indomethacin ,Renal function ,Physical exercise ,Acebutolol ,Renin-Angiotensin System ,Internal medicine ,Prazosin ,medicine ,Albuminuria ,Humans ,Exercise ,Kidney ,business.industry ,Hemodynamics ,Filtration fraction ,Proteinuria ,Endocrinology ,medicine.anatomical_structure ,Renal blood flow ,Female ,business ,medicine.drug - Abstract
Strenuous physical exercise causes transient proteinuria and renal hemodynamic changes: decrease of renal blood flow and to a lesser extent of the glomerular filtration rate, and an increase of the filtration fraction. However, the mechanisms of these modifications are still poorly understood. In order to elucidate them we performed maximal exercise tests on 8 untrained healthy volunteers after inhibition of the renin-angiotensin system (RAS) by captopril, the sympathetic nervous system by a beta-blocking drug (acebutolol) or an alpha-blocking drug (prazosin) and the prostaglandin system by indomethacin. Urinary albumin excretion was measured in every subject first at rest (AB) and then after exercise (AA) performed successively without and with blockade by each of theses drugs. AA-AB difference in the captopril test (12.04 +/- 6.11 micrograms/min) compared to that in the control test (68.91 +/- 25.18 micrograms/min) was significantly reduced (p less than 0.02). This difference remained unchanged after acebutolol (59.87 +/- 21.91 micrograms/min, p = 0.62), prazosin (35.23 +/- 27.80 micrograms/min, p = 0.21) and indomethacin (55.21 +/- 28.43 micrograms/min, p = 0.35). There was a negative correlation between the lowering of AA elevation and the rise in plasma renin activity in the captopril test (r = 0.64; p less than 0.03). Only acebutolol decreased systolic blood pressure significantly. These results suggest that the RAS plays a major role in postexercise proteinuria. We hypothesize that stimulation of this system induces an increase of efferent glomerular artery constriction and consequently of glomerular transcapillary pressure and the filtration fraction. Captopril seems able to prevent these hemodynamic changes.
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