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Objective. To identify the potential epizootic and epidemiological risks arising from the development of the infrastructure of Platov Airport in the territory adjacent to the airport for the development, if necessary, of a set of anti-epidemic and preventive measures. Materials and methods. Epizootological monitoring was carried out in the vicinity of Platov airport, as well as on the territory of the complex itself for three seasons (20192021). The capture of small mammals was carried out according to the standard method of trap-lines with Hero crushers; 1200 trap-days were accumulated. Route records of bats with the determination of their species were carried out. The species belonging of blood-sucking arthropods was determined using determinants. Regulatory support for the above monitoring was formed in accordance with the current normative and methodological documents: SanPiN 3.3686-21 "Sanitary and Epidemiological Requirements for the Prevention of Infectious Diseases"; MP 3.1.0211-20 "Trapping, Accounting and Forecasting the Number of Small Mammals and Birds in Natural Foci of Infectious Diseases"; MU 3.1.3012-12 "Collection, Accounting and Preparation for Laboratory Examination of Blood-sucking Arthropods in Natural Foci of Dangerous Infectious Diseases". Laboratory studies of samples of extracted biomaterial for the search of markers of pathogens of natural focal infections were carried out taking into account the requirements of current regulatory documents. Samples for laboratory testing were formed in compliance with the principle of "one point of collection of material, one time of collection of material, one type of material". Results. The results of epizootological monitoring of the territory of the Platov airport (Rostov-on-Don) are presented, according to which a real possibility of the development of epizootics of dangerous infectious diseases among small mammals living in the adjacent territory to the Platov airport has been established. In order to eliminate potential risks that can lead to complications of the epidemiological situation, it is necessary to carry out planned deratization and acaricide treatments on the territory of Platov airport. The continuation of regular epizootological monitoring of the airport territories and adjacent territories remains very relevant. Conclusions. The results of epizootological monitoring of the territory of the Platov International Airport (Rostov-on-Don) revealed the presence of mouse-like rodents penetrating from the surrounding fields, including those belonging to groups I and II of infectious sensitivity to tularemia, which form potential epizootological risks. A comprehensive laboratory study of biological material obtained from mouse-like rodents captured during epizootological monitoring did not reveal markers of pathogens of natural focal infections. At the same time, systematic regular epizootological monitoring of the airport territory is necessary due to the presence in the territories surrounding the airport complex of natural foci of particularly dangerous infections common to humans and animals, where mouse-like rodents live and reproduce, including house mice and rats, capable of migrating and inhabiting residential and warehouse premises and in case of activation of epizootic process to introduce infection into the territory of the airport complex, especially in autumn and winter.

The analysis of changes of staff structure of The Center of Hygiene and Epidemiology in the Republic of Tatarstan (Tatarstan) during 2005–2014 is submitted. For the studied period in structure of establishment the number of branches, divisions, including laboratory was reduced. In the staff of institution the share of experts with the higher and secondary medical education decreased, and growth of number «other experts with the higher education» is noted.

190 V. cholerae cultures isolated by the specialized antiepidemic brigade of the Rostov-on-Don Research Institute for Plague Control in the Khasavyurt, Babayurt and Novolaksk regions of Daghestan in August-October 1994. All isolated strains were typical with respect to their morphological and cultural properties and could be agglutinated (with the exception of one strain) to the titer or half-titer with diagnostic cholera serum and Ogawa serum. 4 strains had signs of RO-dissociation, 4 strains were agglutinated with Inaba serum in a low titer. All strains were resistant to diagnostic bacteriophages. Cyproxin and doxicycline proved to be the most active agents for the treatment of patients. Agglutinins, vibriocidins and antidermonectrotic antibodies in diagnostic titers were detected in the sera of all patients and Vibrio carriers.

A set of 10 monoclonal antibodies specific for vibrio species and of 5 monoclonal antibodies specific for serovar (Ogawa) was studied. These monoclonal antibodies were directed toward V. cholerae O1 antigen in agglutination reaction and on slide plates. Monoclonal antibodies agglutinating typical strains of cholera vibrios with titration range from 1: 6000 to 1: 25,000 were selected. MA were revealed to interact with cholera vibrio strains with reduced agglutinability. The set of agglutinating O monoclonal immunoglobulins was developed for laboratory identification of cholera O1 vibrios.