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Introduction Diabetes mellitus (DM) is associated with significant morbidity and mortality due to vascular complications. Diabetic retinopathy (DR) is the most common microvascular complication of diabetes. Videocapillaroscope has been the predominant tool for nailfold capillary analysis. We aimed at using the commonly available handheld dermatoscope and observe changes in the nailfold capillaries as a part of evaluating diabetic microvascular involvement. Materials and methods A cross-sectional observational study involving 262 patients of diabetes mellitus and 150 controls was conducted for nailfold capillaroscopic changes using a hand-held dermatoscope over a period of 1 year. Results All the capillaroscopic variables like tortuosity, increased capillary density, neoangiogenesis, microhaemorrhages, avascular areas, crossing and meandering capillaries and receding capillaries were significantly more among diabetic than healthy controls. Patients with diabetic retinopathy had significant nailfold capillaroscopic features as compared to patients without DR (P value < 0.001). Neoangiogenesis, receding capillaries and avascular area were significantly higher in proliferative DR as against nonproliferative DR (P < 0.001). A positive association was found between the duration of DM and HbA1c values and NFC features. A decrease in the visualisation of NFC features was noted with increasing skin tone. The difference was significantly more between Fitzpatrick skin phototypes 4 and 5. Limitations The study was limited by its qualitative nature of accessing parameters as precise quantitative assessment of various findings cannot be done by a hand-held dermatoscope. Conclusion Nailfold capillaroscopy is a quick, cost-effective screening tool for identifying patients at high risk of DR in patients with skin of colour. NFC findings may mirror DR changes. The qualitative findings of NFC using a hand-held dermatoscope were comparable to other modes of nailfold capillaroscopy.

Aim and Objective To determine the efficacy of antenatal corticosteroids given in the late preterm period. Methodology We conducted a retrospective case–control study on patients with singleton pregnancies who were at a risk of delivering in the late preterm period (34 weeks to 36 weeks 6 days). A total of 126 patients who had received antenatal corticosteroids (prenatal administration of either betamethasone or dexamethasone, minimum one dose) during the late preterm period were taken as cases, and 135 patients who had not received steroids antenatally due to various reasons, for example, who were clinically unstable, presented with active bleeding, non-reassuring foetal status that obligated an imminent delivery and those in active labour were included as controls. The various neonatal outcomes like APGAR score at one and five minutes, incidence of admission and duration of stay in neonatal intensive care unit (NICU), respiratory morbidity, requirement of assisted ventilation, intraventricular haemorrhage (IVH) necrotizing enterocolitis, transient tachypnea of the newborn, respiratory distress syndrome, use of surfactant, neonatal hypoglycaemia, hyperbilirubinemia requiring phototherapy, sepsis and neonatal mortality were compared between the two groups. Results The baseline characteristics of both groups were comparable. There was a lower incidence of admissions to neonatal intensive care unit (NICU) (15% vs. 26%, p = 0.05), respiratory distress syndrome (5% vs. 13%, p = 0.04), requirement of invasive ventilation (0% vs. 4%, p = 0.04) and hyperbilirubinemia requiring phototherapy (24% vs. 39%, p = 0.02) in the babies of the group that received steroids compared to the control group. The rate of overall respiratory morbidity in the neonates was lowered after giving steroids (16% vs. 28%, p = 0.04). The incidence of neonatal necrotizing enterocolitis, hypoglycaemia, IVH, TTN, sepsis and mortality between the two groups was not significant (p > 0.05). Conclusion Antenatal corticosteroids administered to patients between 34 and 36 weeks 6 days of gestation reduce respiratory morbidity, requirement of invasive ventilation, respiratory distress syndrome, hyperbilirubinemia requiring phototherapy and the incidence of NICU admissions in the newborns.

Introduction Heparin is useful in inflammatory conditions for amelioration of symptoms by altering the microcellular environment. This study was aimed at evaluation of the role of heparin in patients with cellulitis on antibiotics. Methodology In our prospective nonrandomized comparative study, the subjects were divided into two groups: group A treated with subcutaneous injection of unfractionated heparin plus antibiotics and group B with antibiotics alone. Comparison was done in terms of improvement in clinical parameters like erythema (cellulitis area), edema (measuring limb girth), pain (visual analog scale), total leucocyte count, and duration of hospital stay. Results Total of 96 patients were divided into two groups of 48 each. In the experimental group, there was improvement in mean area of cellulitis with decrease of 32.36% compared with 10.99% in controls treated with antibiotics at day 5 (p Conclusion The addition of heparin with antibiotic therapy in cellulitis hastens recovery with faster amelioration of symptoms and shorter hospital stay.

The NEP 2020 is a visionary policy of the Government of India that promises to transform education for all. NEP 2020 lays impartial to potential of each and every individual and to cultivate ingenuity and skills development. Education is necessary in all aspect of the economy to ensure better growth, employment opportunities, promote innovation, democratic progress, strengthen rule of law, invigorate civic values etc. Teachers are one of the major stakeholders in education. This research is a descriptive study on the perception of college teachers towards the important features of NEP 2020 and brings out suggestions thereby. This study analyses the agreement and disagreement of teachers towards the highlighted features of NEP 2020 on Indian Higher education. Quantitative techniques were used in this analysis and draw conclusion. This research paper analyses the crucial part of policy that aim Indian higher education system like – research culture, use of regional language, privatisation, workload, Establishment of NPST (National Professional Standards for Teachers), training etc. Study is focused on college teachers of southern Kerala and sampling was done through stratified sampling technique.

In this innovative study, Gita V. Pai traces the history of the Pudu Mandapam (Tamil, 'new hall') – a Hindu temple structure in Madurai – through the rise and fall of empires in south India from the seventeenth century to the present. This wide-ranging work illustrates how south Indian temples became entangled in broader conflicts over sovereignty, from early modern Nayaka kings, to British colonial rule, to the post-independence government today. Drawing from methodologies in anthropology, religious studies, and art and architectural history, the author argues that the small temple site provides profound insight into the relationship between aesthetics, sovereignty, and religion in modern South Asia.

Seashell powder (SSP) is a waste from aquatic life that is generally available near the coastal region. Due to its high calcium content, SSP can be utilized as a supplementary cementitious binder. SSP can be used as a sustainable binder to replace ordinary Portland cement (OPC) and significantly reduce the carbon footprint. The present study investigates the effects of SSP and waste glass powder (WGP) on the fresh, mechanical, and microstructure properties of high-strength concrete (HSC). The SSP utilized in this research was varied, with 5%, 10%, and 15% cement replacement levels. The impact of WGP was also observed with two replacement levels, 5% and 10%, replacing natural sand. The slump flow of all the HSC mixes varied between 700 and 785 mm. A maximum compressive strength of 112.91 MPa was found for the C75SSP5 mix at 56 days. The split tensile strength values of all the HSC mixes were found in a range from 5.45 to 10.56 MPa. The modulus of elasticity values of all the HSC mixes were found to lie between 40.2 and 46.8 GPa. The lowest water absorption was observed in the mix containing 5% SSP. The SEM image of the HSC with increased SSP showed that it was denser and had fewer unreacted particles. XRD and EDS showed the presence of various gels, such as calcium silicate hydrates (CSHs), ettringite, calcium hydroxide (CH), and calcium carbonate (CC). The predicted equations for its split tensile strength, flexural strength, modulus of elasticity, and water absorption were also carried out in the present research.

TRITON-based dispersion methodology (Method 1) and touchstone-based methodology (Method 2) for the direct non-destructive compositional analysis of (Th, U)O2 fuel pellets.

Direct non-destructive evaluation of micro-homogeneity and agglomerate sizes (red zones) in nuclear fuel pellets prepared via different fabrication routes using μ-XRF.

Background: Obesity is considered to have increased in epidemic proportions throughout the globe, more so in developing countries like India. Obesity is primarily associated with sedentary lifestyle with poor dietary choices and less physical activity. Television is one of the sedentary activities is often associated with consumption of oily foods. This has compounded the problem of obesity and lead to associated health problems including hypertension, diabetes and metabolic syndrome. Results: The questionnaire study involved 369 subjects in a rural setup. Majority of the studied population watched TV and major chunk of them were middle aged people. The time involved in TV viewing was higher in the same population, which is a sedentary form of activity. Statistical correlation was observed between education, income status, oily food consumption and Television viewing. Physical activity was notably higher in the non-TV viewing subjects. BMI, which is measure of obesity, was increased in the TV viewers, coupled with lifestyle disorders like Diabetes, Hypertension and arthritis. Alcohol and tobacco usage too was shown to increase with Television viewing. The dietary choices of TV watching subjects were of less nutritive value with more sugar and oil consumption. Conclusion: Indian studies correlating television viewing and obesity in the adult population are lacking. The study shows a significant correlation of increased TV viewing with obesity in the middle-aged population and the associated health problems related to it.

A technique for measuring the heat flux from the shock-compressed gas in front of the point of contact to the surface of the colliding plates has been developed. The experimental values of the heat flux are obtained, which are in satisfactory agreement with theoretical calculations. For the first time experimentally proved a significant effect of preheating of plates before collision for various materials. The effect consists in heating the surface of the plates, depending on their dimensions and properties, up to 1000 ° C and above.

Introduction and Aim:Pregnancy is a normal physiological state during which women experience a lot of internal bodily changes. Gestational diabetes mellitus (GDM) is a complication of pregnancy which is characterized by hyperglycemia due to an error in carbohydrate metabolism. During pregnancy changes in metabolism may induce oxidant stress and it may increase in GDM. The present study was done to compare serum calcium, magnesium and total antioxidant activity in pregnant women with and without hyperglycemia. Materials and Methods: The study was conducted for a period of one year. Total 67 participants were included and their serum samples were analyzed for serum calcium magnesium and total antioxidant activity. Among these 29 were GDM (43%) and 38 were non-GDM (57%). All study subjects were on supplementation of calcium, iron and folic acid. Results: In our study, there were no significant difference in serum calcium, magnesium and antioxidant activity between GDM and non GDM women. Conclusion: Calcium, magnesium and antioxidant activitywere maintained well both in pregnant women GDM and non GDM, this may be due to beneficial effect of calcium, iron, folic acid supplementation.

Physiological and biochemical changes occur in pregnancy to nurture the developing fetus. Pregnancy-related experience is unique to every woman. Pregnancy symptoms and complications can range from mild to severe. Many women can lower their risk by performing different therapies. In this context, the present study targets to evaluate the efficacy of integrated yoga consisting of (asanas and pranayama) on pregnancy to reduce the risk of complications. This study is a prospective randomized controlled single-blinded trial with parallel arms: the intervention arm received specific integrated yoga therapy; the control arm received routine standard care from 18 to 22 weeks of gestation until delivery. The incidence of preeclampsia and preterm delivery was lower in the intervention arm. Women in the intervention arm delivered at higher gestational age. Apgar scores and birth weights of neonates were significantly higher in the intervention arm. The findings suggest that yoga is a safe and effective intervention during pregnancy to reduce or prevent pregnancy-related complications. However, further randomized controlled trials are needed to provide firmer evidence regarding the utility and validity of yoga intervention during pregnancy.

Objectives To document serious adverse events (SAE) of prolonged prednisolone use in two double-blind randomized clinical trials (RCT). In the first RCT, treatment effectiveness on restoring nerve function of a 20-week prednisolone regimen was compared with a 32-week course. In the second RCT, patients with subclinical neuropathy received either 20 weeks prednisolone or placebo to assess whether prednisolone could prevent the development of clinical neuropathy. In both trials, patients received a prednisolone starting dose according to weight: high weight (≥50 kg) started at 60 mg and low weight (

In this study, a layered composite material consisting of alternating aluminum and niobium layers and cladded on both sides with titanium plates was obtained by explosive welding. Microstructure of the composite was thoroughly studied using scanning electron microscopy (SEM) and transmission electron microscopy (TEM), as well as by energy dispersive X-ray spectroscopy (EDX) and electron backscattered diffraction (EBSD). Microhardness measurements, tensile test, and impact strength test were carried out to evaluate the mechanical properties of the composite. Formation of mixing zones observed near all interfaces was explained by local melting and subsequent rapid solidification. Mixing zones at Nb/Al interfaces consisted of metastable amorphous and ultrafine crystalline phases, as well as NbAl3 and Nb2Al equilibrium phases. Niobium grains near the interface were significantly elongated, while aluminum grains were almost equiaxed. Crystalline grains inside the mixing zones did not have a distinct crystallographic texture. Microhardness of Al/Nb mixing zones was in the range 546–668 HV, which significantly exceeds the microhardness of initial materials. Tensile strength and impact strength of the composite were 535 MPa and 82 J/cm2, respectively. These results confirm the high bonding strength between the layers.

In this work we have developed a Total reflection X-Ray Fluorescence (TXRF) based methodology for the determination of uranium in natural water samples at ultra-trace concentration level. The methodology involves functionalization of quartz sample supports used for TXRF measurements with (3-Amidoxy) triethoxysilane, which has very high uranium uptake efficiency. (3-Amidoxy) triethoxysilane has been synthesized from (3-Cyanopropyl) triethoxysilane (CPTS). This amidoxime functionalized sample supports, simply needed to be dipped in the uranium solution for 3 h after which, it can be directly taken for TXRF measurements. The developed methodology is very fast, simple with less sample preparation steps involved. The present work utilizes Rayleigh scattered peak to construct the calibration curve for the quantification purpose. The developed methodology has improved accuracy as well as precision for the quantification of uranium at such low concentrations level. The detection limit and accuracy obtained are 0.013 ng/mL (13 ppt) and 1.9%, respectively which are the lowest using any X-Ray Fluorescence based method, to the best of our knowledge. The method was successfully applied for the U determination in natural water samples like ground water, river water and sea water.

Instruments used in assisted vaginal birth have seen little innovation for decades. Due to the risk of trauma and technical difficulty incurred during forceps delivery, instrumental deliveries are on a decline, and the global rate of primary cesarean birth is rising. The novel Paily Obstetric Forceps (POF) features a compact, lighter design with thinner blades, designed to increase operator comfort and minimize maternal and neonatal injuries. We aim to determine the feasibility and safety of POF in achieving vaginal birth compared to a ventouse device with a 50 mm silastic cup.We conducted a single-blinded, parallel arm, randomized clinical trial of the novel POF vs a ventouse device, in patients undergoing indicated assisted vaginal birth, at a tertiary care obstetric unit. We randomized 100 patients to be allocated on a 1:1 ratio to both intervention arms. Primary outcome was the proportion of successful instrumental deliveries. Secondary outcomes were the number of pulls required during traction and any maternal or neonatal adverse events.The POF was significantly more successful in achieving vaginal birth than the ventouse device (n = 50/50, 100 % vs n = 42/50, 84 %, p = 0.006). Operators reported requiring significantly fewer pulls during POF traction than ventouse. POF demonstrated a higher risk for maternal trauma (RR = 3.2, 95 % CI = 1.5 to 6.9, NNH = 2.7) but a lower risk for neonatal injury (RR = 0.6, 95 % CI = 0.3 to 1, NNH = 5.7). Maternal and neonatal recovery durations were comparable. There were no incidences of maternal or neonatal mortality.The POF can be used in indicated assisted vaginal birth with superior success rates and better neonatal outcomes than ventouse. Other obstetric forceps must be standardized to conduct larger superiority trials of forceps designs.

In the adult and pediatric critical care population, point-of-care ultrasound (POCUS) can aid in diagnosis, patient management, and procedural accuracy. For neonatal providers, training in ultrasound and the use of ultrasound for diagnosis and management is increasing, but use in the neonatal intensive care unit (NICU) is still uncommon compared with other critical care fields. Our objective was to describe the process of implementing a POCUS program in a large academic NICU and evaluate the role of ultrasound in neonatal care during early adaption of this program. A POCUS program established in December 2018 included regular bedside scanning, educational sessions, and quality assurance, in collaboration with members of the cardiology, radiology, and pediatric critical care divisions. Core applications were determined, and protocols outlined guidelines for image acquisition. An online database included images and descriptive logs for each ultrasound. A total of 508 bedside ultrasounds (76.8% diagnostic and 23.2% procedural) were performed by 23 providers from December 2018 to December 2020 in five core diagnostic applications: umbilical line visualization, cardiac, lung, abdomen (including bladder), and cranial as well as procedural applications. POCUS guided therapy and influenced clinical management in all applications: umbilical line assessment (26%), cardiac (33%), lung (14%), abdomen (53%), and cranial (43%). With regard to procedural ultrasound, 74% of ultrasound-guided arterial access and 89% of ultrasound-guided lumbar punctures were successful. Implementation of a POCUS program is feasible in a large academic NICU and can benefit from a team approach. Establishing a program in any NICU requires didactic opportunities, a defined scope of practice, and imaging review with quality assurance. Bedside clinician performed ultrasound findings can provide valuable information in the NICU and impact clinical management.· Use of point-of-care ultrasound is increasing in neonatology and has been shown to improve patient care.. · Implementation of a point-of-care ultrasound program requires the definition of scope of practice and can benefit from the support of other critical care and imaging departments and providers.. · Opportunities for point-of-care ultrasound didactics, imaging review, and quality assurance can enhance the utilization of bedside ultrasound..

Many aspects of our life are affected by technology. One of the most discussed advancements of modern technologies is artificial intelligence. It involves computational methods which in some way mimic the human thought process. Just like other branches, the medical field also has come under the ambit of artificial intelligence. Almost every field in medicine has been touched by its effect in one way or the other. Prominent among them are medical diagnosis, medical statistics, robotics, and human biology. Medical imaging is one of the foremost specialties with artificial intelligence applications, wherein deep learning methods like artificial neural networks are commonly used. artificial intelligence application in dermatology was initially restricted to the analysis of melanoma and pigmentary skin lesions, has now expanded and covers many dermatoses. Though the applications of artificial intelligenceare ever increasing, large data requirements, interpretation of data and ethical concerns are some of its limitations in the present day.

Objective To determine the rates of high-risk infant follow-up (HRIF) attendance and the characteristics associated with follow-up among infants with hypoxic-ischemic encephalopathy (HIE) in California. Study design Using population-based datasets, 1314 infants with HIE born in 2010-2016 were evaluated. The characteristics associated with follow-up were identified through multivariable logistic regression. Results 73.9% of infants attended HRIF by age 1. Follow-up rates increased and variation in follow-up by clinic decreased over time. Female infants; those born to African-American, single, less than college-educated, or publicly insured caregivers; and those referred to high-volume or regional programs had lower follow-up rates. In multivariable analysis, Asian and Pacific Islander race/ethnicity had lower odds of follow-up; infants with college- or graduate school-educated caregivers or referred to mid-volume HRIF programs had greater odds. Conclusion Sociodemographic and program-level characteristics were associated with lack of follow-up among HIE infants. Understanding these characteristics may improve the post-discharge care of HIE infants.

Fluorescence imaging using indocyanine green (ICG) has revolutionized commonly performed general surgical procedures by providing superior anatomic imaging and enhancing safety for patients. ICG, when injected, shows a bright green fluorescence when subjected to the near infra-red (NIR) spectrum.We employed the use of ICG in Laparoscopic cholecystectomy, Intestinal Colorectal Anastomosis and Hernia to assess vascularity of resected ends and bowel viability, Sentinel Lymph node mapping, Vascular surgery to assess amputation stump success and in assessing Flap Vascularity and healing.ICG when administered had successfully shown bright green fluorescence in different cases thereby aiding in surgical procedures.Routine intraoperative use of ICG could pave the way for a more objective assessment of different surgical circumstances and thereby reduce personalized barriers to aciurgy. ICG fluorescence therefore seems to be a promising apparatus in standard general surgical procedures minimizing untoward errors and improving patient conformance.

The present study explores the application of the micro-Raman spectroscopy technique to discriminate normal and cervicitis condition from cervical malignancy by analyzing the Raman signatures of tissues and plasma samples of the same subjects. The Raman peaks from tissue samples at 1026 cm

This paper presents the results of measuring the temperature at the joint boundary and in the heat-affected zone using the developed computational and experimental methods based on the use of natural thermocouples. It is shown that in explosion welding of materials with developed wave formation at the joint boundary, the main heat release occurs in a narrow region limited by the size of the generated waves.

To measure the temperature of shaped-charge jets, we fabricated three-layer copper–copper–Constantan liners consisting of a solid copper conical shell with a cone angle of 45° and a wall 1.5 mm thick and a shell pressed into it and rolled from a 1.0 mm thick copper sheet clad on the inside with a Constantan layer 0.5 mm thick by explosive welding. Then, the Constantan layer was partially removed so that only the upper third of the inner surface of the shells remained lined with Constantan. The thickness of the Constantan layer was chosen such that the head of the shaped-charge jet consisted only of Constantan, and the tail of copper, as determined from a thin section of the recovered slug. As a result, a copper–Constantan thermocouple was formed. At the moment of impact of the bimetallic jet on a target, the thermo-EMF signal was measured with an oscilloscope. The obtained thermo-EMF value corresponds to a temperature of 800 ± 80.

A term male infant is seen with a peeling erythematous rash at birth. ### Prenatal and Birth Histories ### Family History ### Presentation after Birth Diffuse erythroderma with desquamative scales on face, trunk, and extremities but no mucosal lesions were noted immediately at birth. The skin was abnormal with generalized erythematous and peeling appearance. He was transferred to a level IV NICU shortly after birth because of concerning appearance of the rash. ### Vital Signs ### Physical Examination

A case-control study with 6 months of patient follow up. This study sought to determine if surgery followed by rehabilitation for patellar instability could restore normal gait function. A previous study has established abnormalities in gait pattern and joint congruence in patients with a history of patellar instability. We hypothesised that surgery for patellofemoral instability would improve knee function. Eight human patients (mean age 29, range 17-42) who were awaiting patella stabilisation surgery (5 tibial tuberosity osteotomy, 2 medial patellofemoral ligament reconstruction, 1 trochleoplasty) were compared against eight normal Controls (mean age 28, range 19-31). Patients were assessed pre-operatively and six months after surgery by biomechanical gait analysis. Gait trials involved simultaneous collection of kinematic and force data. Patients were grouped into two subgroups pre-operatively based on knee joint net moment during stance, and their joint moments during stance pre- and post-operatively were compared against the Control subjects. In pre-operative gait analysis, four patients (P1) produced some extensor moment in early stance and four (P2) demonstrated a severe gait deficiency with failure to generate a knee extensor moment during stance. Normalisation in gait pattern was observed in all patients post-operatively. Those who had the most severe gait abnormality (P2) demonstrated the most improvement in their knee joint moments. Improvements were observed in the milder (P1) cases, but these were less dramatic. Patella stabilisation by surgery can restore normal gait function. Normalising the anatomy of the knee extensor mechanism is the objective of surgery. Normal anatomy facilitates the rehabilitation objectives of optimising extensor function during the weight-bearing phase of gait.

Fe2O3 nanoparticles immobilized on SiO2 xerogel beads were prepared using a sol–gel-based method. Two different acid catalysts, namely citric acid and acetic acid, were used to modify the preparative conditions and materials with desirable surface characteristics and pore structure. Three sets of samples with 1, 5, and 10 wt% Fe2O3 dispersed on silica beads were synthesized. A decrease in the specific surface area from 457.1 to 144 m2/g and pore volume from 0.558 to 0.172 cm3/g was observed when the iron content was increased from 1 to 10 wt% in the case of acetic acid–catalyzed sample. A similar decreasing trend was observed in citric acid–catalyzed samples due to the precipitation of Fe2O3 in the pores. XRD studies revealed the presence of both α-Fe2O3 and γ-Fe2O3 phases in the 1000 °C calcined samples. The Mossbauer data showed that the fraction of α-Fe2O3 decreased while γ-Fe2O3 increased in samples with Fe content. Structural investigations carried out by Mossbauer spectroscopy also revealed the oxidation state of Fe in the sample as + 3. From scanning electron micrographs (SEM), sub-micron size particles of Fe2O3 homogeneously dispersed on SiO2 having faceted geometry could be revealed. TPR results of these samples showed a good interaction of Fe2O3 particles with the silica support with a distinct reduction profile compared to bulk Fe2O3 and indicated that Fe2O3 nanoparticles were homogeneously distributed throughout SiO2 surface and within the mesoporous structure of SiO2. Catalytic activity measurement of these catalysts towards sulfuric acid decomposition reactions at 800 °C showed a constant yield of ~ 55% of SO2 at a WHSV of 27 g acid g−1 h−1. The catalyst showed a good stability for more than 12 h at 800 °C for continuous operation.

A uterine epithelioid leiomyosarcoma is a type of uterine mesenchymal tumour that arises from the smooth muscle lining the walls of the uterus. The specific cause of leiomyosarcoma is uncertain, with uterine leiomyosarcoma accounting for 5 to 10% of cases. The most prevalent subtype of uterine sarcoma, leiomyosarcoma, accounts for 1-2 percent of all uterine malignancies. Recent application of molecular techniques has identified numerous lesions with distinctive genetic abnormalities and clinicopathological characteristics. Menopausal women who are not on hormonal replacement medication and have tumour development should be suspected of malignancy. A 64-year-old woman had reached menopause 16 years prior and had been experiencing postmenopausal haemorrhage for the past two months, with a palpable mass measuring 16 weeks in size. The whorled mass lesions, endometrium, and myometrium could not be seen separately on ultrasonography. Uterus with both ovaries removed. Intraoperative investigations revealed a 16-week-old uterine mass with a diameter of 15x15 cm and a weight of 1kg, as well as an intramural fibroid. On cut section, necrotic and haemorrhagic regions with degenerative alterations suggest cancer. Epithelioid leiomyosarcoma was discovered using histopathology and immunohistochemistry.