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Your search keyword '"V. Jo Davisson"' showing total 98 results

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1. Addressing the unmet clinical need for low-volume assays in early diagnosis of pancreatic cancer

2. Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning.

3. Evaluation of Phenol-Substituted Diphyllin Derivatives as Selective Antagonists for Ebola Virus Entry

5. Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors.

6. Flexibility of PCNA-protein interface accommodates differential binding partners.

7. Discrimination of mucinous pancreatic cysts using an enzymatic turnover assay to improve clinical diagnostic accuracy

8. Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 function.

9. Differential mitochondrial toxicity screening and multi-parametric data analysis.

10. Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation

11. A Chemogenomic Screening Platform Used to Identify Chemotypes Perturbing HSP90 Pathways

12. Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning

13. Characterization of lovastatin–docosahexaenoate anticancer properties against breast cancer cells

14. Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase

15. Substrate Activation and Conformational Dynamics of Guanosine 5′-Monophosphate Synthetase

16. Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors

17. Total Synthesis of Iejimalide B

18. A machine-learning approach to detecting unknown bacterial serovars

19. Multiplexed concentration quantification using isotopic surface-enhanced resonance Raman scattering

20. Accurate Concentration Measurements Using Surface-Enhanced Raman and Deuterium Exchanged Dye Pairs

21. Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults

22. Fluorogenic Transformations Based on Formation of CC Bonds Catalyzed by Palladium: An Efficient Approach for High Throughput Optimizations and Kinetic Studies

23. Effects of hindlimb unloading and bisphosphonates on the serum proteome of rats

24. Considerations of Protein Subpockets in Fragment-Based Drug Design

25. Synthesis and Anticancer Activity of Brefeldin A Ester Derivatives

26. Structural Elements in IGP Synthase Exclude Water to Optimize Ammonia Transfer

27. Detection of the site of phosphorylation in a peptide using Raman spectroscopy and partial least squares discriminant analysis

28. Adaptive silver films for surface-enhanced Raman spectroscopy of biomolecules

29. Surface-Enhanced Raman Difference between Human Insulin and Insulin Lispro Detected with Adaptive Nanostructures

30. Crystal Structure of Imidazole Glycerol-phosphate Dehydratase

31. Substrate-Induced Changes in the Ammonia Channel for Imidazole Glycerol Phosphate Synthase

32. High-Throughput Flow Cytometry

33. Flexibility of PCNA-Protein Interface Accommodates Differential Binding Partners

34. Crystal Structure of Imidazole Glycerol Phosphate Synthase

35. Template directed incorporation of nucleotide mixtures using azole- nucleobase analogs

36. Sequence Analysis of theCandida albicans ADE2 Gene and Physical Separation of the Two Functionally Distinct Domains of the Phosphoribosylaminoimidazole Carboxylase

37. Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site

38. Escherichia coli imidazoleglycerol phosphate dehydratase: spectroscopic characterization of the enzymic product and the steric course of the reaction

39. Portable bacterial identification system based on elastic light scatter patterns

40. Differential Mitochondrial Toxicity Screening and Multi-Parametric Data Analysis

41. High-Throughput Secondary Screening at the Single-Cell Level

42. A plasmid-based approach for the synthesis of a histidine biosynthetic intermediate

43. A Machine-Learning Approach to Detecting Unknown Bacterial Serovars

44. Farnesyl-diphosphate synthase. Catalysis of an intramolecular prenyl transfer with bisubstrate analogs

45. Farnesyl-diphosphate synthase. Interplay between substrate topology, stereochemistry, and regiochemistry in electrophilic alkylations

46. Mechanism-based inactivation of Escherichia coli .beta.-hydroxydecanoyl thiol ester dehydrase: assignment of the imidazole nitrogen-15 NMR resonances and determination of the structure of the alkylated histidine

47. Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide)

48. Characterization of anticancer properties of 2,6-diisopropylphenol-docosahexaenoate and analogues in breast cancer cells

49. Interrogating the Mechanism of a Tight Binding Inhibitor of AIR Carboxylase

50. Quantification of isotope encoded proteins in 2-D gels using surface enhanced resonance Raman

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