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In 17-year nested prospective study, the natural dynamics of hypertriglyceridemia (HTG) (development of new cases, regress), cardiovascular mortality and other mortality of patients with HTG have been examined. The nest included 630 men and 916 women from 20 to 59 years old. The HTG incident in the nest was 8.24 cases per 1000 people*years of observation. Among people 20—29 years old, new HTG cases were observed more often in men, while in the age interval of 30—59 years, new cases were more often observed in women. For the period of observation, the HTG occurrence increased 1.6 times in men and 2.1 times in women. HTG is characterized by the low course stability, and the regress level is independent of sex. Among men and women, Among men and women with HTG, brain stroke and cardiovascular mortality is higher than that among people with the normal triglyceride (TG) level. The TG level did not affect the total men mortality.

In 17-year prospective cohort study, we analyzed the influence of smoking and drinking on the formation of cardiovascular and general mortality of adult people in Tomsk. The cohort included 1 546 people (630 men and 916 women) aged 20—59 years. It has been found that due to smoking the 17-year risk of death by any cause increases 2.4 times among men and 2.7 times among women. The increase in the frequency of drinking in the male population increase the risk of death by any cause 1.6 times (for men drinking once a month or more rarely), 2.4 times (for men drinking once a week and more rarely, but more often than once a month), and 3.8 times (for men drinking more often than once a week). The risk of death by cardiovascular diseases increases 1.7, 2.9, and 4.9 times, respectively.

Aim. To study the cross-sectional prevalence of overweight (OW) in men and women, in regard to their spouses’ body weight (BW), as well as to assess the BW dynamics in participants and their spouses over 15 years of the prospective follow-up. Material and methods. In the screening study, body mass index (BMI) was assessed in 425 married couples. The repeat assessment, performed 15 years later, included 232 couples who were still married. OW was diagnosed in subjects with BMI ≥25 kg/m2. Results. In the wives of OW men, OW prevalence was higher (76,2%) than in the spouses of non-OW men (61,3%; p