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14. Morbidity in Depressive Disorders

Author

Baldessarini, Ross J., Forte, Alberto, Selle, Valerio, Sim, Kang, Tondo, Leonardo, Undurraga, Juan, and Vázquez, Gustavo H.

Published
2017

17. Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters

Author

Tondo, Leonardo, Abramowicz, Maria, Alda, Martin, Bauer, Michael, Bocchetta, Alberto, Bolzani, Lorenza, Calkin, Cynthia V., Chillotti, Caterina, Hidalgo-Mazzei, Diego, Manchia, Mirko, Müller-Oerlinghausen, Bruno, Murru, Andrea, Perugi, Giulio, Pinna, Marco, Quaranta, Giuseppe, Reginaldi, Daniela, Reif, Andreas, Ritter, Jr., Philipp, Rybakowski, Janusz K., Saiger, David, Sani, Gabriele, Selle, Valerio, Stamm, Thomas, Vázquez, Gustavo H., Veeh, Julia, Vieta, Eduard, and Baldessarini, Ross J.

Published
2017
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27. Status of Type II vs. Type I Bipolar Disorder: Systematic Review with Meta-Analyses.

Author

Hernandorena, Carolina V., Baldessarini, Ross J., Tondo, Leonardo, and Vázquez, Gustavo H.

Subjects
BIPOLAR disorder, SUICIDE risk factors, ATTEMPTED suicide, PSYCHIATRIC diagnosis, THERAPEUTIC use of lithium, PSYCHOTIC depression, PSYCHIATRIC hospital care
Abstract

Since the status of type II bipolar disorder (BD2) as a separate and distinct form of bipolar disorder (BD) remains controversial, we reviewed studies that directly compare BD2 to type I bipolar disorder (BD1). Systematic literature searching yielded 36 reports with head-to-head comparisons involving 52,631 BD1 and 37,363 BD2 patients (total N = 89,994) observed for 14.6 years, regarding 21 factors (with 12 reports/factor). BD2 subjects had significantly more additional psychiatric diagnoses, depressions/year, rapid cycling, family psychiatric history, female sex, and antidepressant treatment, but less treatment with lithium or antipsychotics, fewer hospitalizations or psychotic features, and lower unemployment rates than BD1 subjects. However, the diagnostic groups did not differ significantly in education, onset age, marital status, [hypo]manias/year, risk of suicide attempts, substance use disorders, medical comorbidities, or access to psychotherapy. Heterogeneity in reported comparisons of BD2 and BD1 limits the firmness of some observations, but study findings indicate that the BD types differ substantially by several descriptive and clinical measures and that BD2 remains diagnostically stable over many years. We conclude that BD2 requires better clinical recognition and significantly more research aimed at optimizing its treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Appendix – Supplemental material for Antidepressant responses in direct comparisons of melancholic and non-melancholic depression

Author

Undurraga, Juan, Vázquez, Gustavo H, Tondo, Leonardo, and Baldessarini, Ross J

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 110319 Psychiatry (incl. Psychotherapy), 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, Appendix for Antidepressant responses in direct comparisons of melancholic and non-melancholic depression by Juan Undurraga, Gustavo H Vázquez, Leonardo Tondo and Ross J Baldessarini in Journal of Psychopharmacology

Published
2020
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