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Příspěvek prezentuje výsledky badatelské činnosti Hany Slovik-Vávrové týkající se mapování dochovaných celokovových mosazných vazeb ve sbírkách institucí České republiky. Celkem zachytila 145 těchto výjimečných vazeb v rozmezí období konce 18. století až 20. let 20. století. Podchyceny jsou knihy z 18 sbírkotvorných organizací. Celokovovým vazbám nebyla dosud věnovaná dostatečná pozornost, ačkoliv se jedná o velice zajímavou kapitolu z dějin knižní vazby. Výsledkem této práce je detailní popsání a podrobná dokumentace všech vybádaných celokovových vazeb. Přínosnou částí je katalog vazeb a ornamentů použitých při výzdobě celokovových vazeb. The article presents the results of the research activities of Hana Slovik-Vávrová concerning the mapping of preserved all-metal brass book bindings in the collections of institutions in the Czech Republic. She has recorded a total of 145 of these exceptional book bindings from between the end of the 18th century and the 1920s, coming from 18 organisations. All-metal book bindings have not been devoted enough attention although they represent a very interesting chapter in the history of book binding. An outcome of this work is a comprehensive description and detailed documentation of all researched all-metal book bindings. A valuable part is a catalogue of book bindings and of ornaments used in the decoration of all-metal book bindings.

Title: Algometric analysis of influence of crimp grip on soft tissues of hand and forearm. Objectives: The main aim of this thesis is comparison and evaluation of changes of nociceptors sensitivity treshold in chosen points of upper extremities area before and after defined strain using pressure algometer. Methods: Data for the experiment was obtained using pressure algometr. Pain threshold was measured in defined 42 points in the order given at each subject firstly before strain and again immediately after defined strain of upper extremities (one minute hangig by the both hands in crimp grip on a campus board in this way: 10 sec strain plus 10 sec break, all six times). Then were measured values statisticaly analysed. Sources for processing of theoretical part of this work were obtained from expert articles and literature which follow up the given task. Results: Statisticaly important results show, that decreasing of pain threshold (on average by 100 - 160 kPa) comes about in tissues of upper extremity immediately after its loading in crimp grip, which means increasing of nociceptors sensitivity. At the same time it has been proved that nociceptors sensitivity in the area of tendon pulleys correlates with frequency of their injury quoted in a literature (that is the highest sensitivity in the...

Charles University in Prague Faculcy of Pharmacy in Hradec Králové Department of Biochemical science Candidate: Hana Vávrová Supervisor: Prof. RNDr. Lenka Skálová, Ph.D. Title of diploma thesis: The effect of new-binding peptides on proliferation of cancer cells Paclitaxel (PTX), alkaloid from the bark of Taxus brevifolia, is used in treatment of ovary, breast and some form of lungs cancer. In Institute of experimental botany in Prague were preparated new conjugates with peptide agonist of receptors for gonadotropin-releasing hormon (GnRH). The previous studies showed that this conjugate have higher or same antiproliferative effect. This antiproliferative effect was compared with PTX on the cell line from breast cancer which have receptors for GnRH. The aim of this study was to compare the anti-proliferativ effect of PTX and its conjugates. For the experiment was chosen to two cell systemes - HCT 8, which is derivate from colorectal adenocarcinoma and primary culture from liver cell from sewer-rat. Both cell lines have not receptors for GnRH. The results were evaluated by three different methods (MTT, NRU and x-Celligence). The conjugates MP 264, MP 211 and MP 260 showed lower antiproliferative effect on the cell line HCT 8 and the conjugate MP 264 and MP 265 showed lower cytotoxic effect than PTX...

There are two parts in my diploma thesis, the practical and the teoretical one. The practical part includes a set of four decorative store tiles on the theme of the Bird{\crq}s flying. The theoretical part consists of my own thought motivation and insperatory sources, which I found in the book by Selma Lagerlöf The Wonderful Adventur of Nils a and in the work of a Dutch graphic designer M. C. Escher. Then I suggest methodic usage how to work with my thesis in the art lessons at the primary school. At the end of theoretical part technologies of processing are described and there is the full picture documentation of the practical part.

This bachelor´s thesis processes the business plan of a specific company, and it is supposed to serve as a basis for the eventual foundation of said company. The company itself can be classified into the service sector of the economy, based on operating a restaurant business by day and music club business by night. The thesis is divided into two parts. The theoretical part describes the structure and the individual parts of the business plan, and describes the various types of businesses in Czech Republic. The practical part describes a specific business plan of a company named 300, including a financial plan for the first year.

Diploma thesis deals with the valuation of the company Iveco a.s., for the management needs. The estimated value refers to December 2016. The basis for the valuation is strategic and financial analysis. The results will be taken into account for establishment of the financial plan, which will be used in the valuation process. Emphasis is placed on yield methods using free cash flow to the firm(FCFF) and economic value added EVA. Both methods are compared with book value of the company.

This thesis focuses on issues connected to analysis of company financing of Lyckeby Amylex, a.s. The aim of this thesis is to describe and analyze sources of financing of company in two ways. First part of analysis focuses on use of company-wide finances within 10 consecutive seasons. As part of the analysis of company-wide financing, the ratios of utilization of equity and liabilities and internal and external sources are monitored. This part is followed by the analysis of financing of the selected investment that was implemented by company. Alternative financing methods of the selected investment are also evaluated under review. In the conclusion of the practical part the financing of the investment as well as its alternatives is evaluated using the EVA indicator, which determines whether the funds have been spent with added value.

Financial Reporting of public-benefit corporations in Czech Republic was significantly changed during a reform of public accounting standards. This thesis focuses on specifics of new Czech legislation in the field of public sector accounting and its differences from international IPSAS standards and shows basic principles of economy of public-benefit corporations on example of one of the most important cultural institution in Czech Republic - National gallery in Prague.

This thesis deals with fundraising of non-profit organisations. The scope of the thesis is to provide the reader with basic information about fundraising, and to apply this information in order to evaluate the fundraising of a selected non-profit organisation. First of all, this work defines the non-profit sector and its long-term sustainability, then the work deals with the fundraising itself. Issues connected with credibility of the organisation and its webpages are included in the part concerning fundraising.These factors establish a competitive advantage in activities that are focused on fundraising. These theoretical foundations are applied on a chosen non-profit organisation, and additionaly, the webpages of the organisation are also analysed, and an ASNO14 non-profit organisation reliability analysis is carried out. The data used in the practical part was collected through an analysis of annual reports of the organisation, webpage analysis and through a personal interview. The ending of this thesis includes an overall evaluation and improvement proposals.

The aim of this diploma thesis is to prepare a business plan for the establishment of a coffeehouse connected with a coworking center. The task of this business plan is to check the feasibility and financial cost of the project and be used as a basis for the real establishment of the enterprise. The theoretical part deals with basic concepts related to entrepreneurship, individual parts of the business plan and issues related to coworking centers. The practical part includes the business plan itself. Attention is paid mainly to the description of business opportunities, competition analysis, business environment analysis, marketing and financial plan, and threat and opportunity analysis. In conclusion, the whole work is evaluated, the fulfillment of the given goal and the recommendation for the founder.

The aim of this Master´s Thesis is to analyse the way in which non-governmental organizations approach the use of the internet for fundraising. The Master´s Thesis explores attitudes of non-governmental organizations towards this medium as well as the factors that motivate these organizations to use the internet. In order to achieve the aim the author carried out qualitative research based on semi-structured interview attended by representatives of a total of ten selected non-governmental organizations. The results show that non-governmental organizations use the internet for fundraising, however there are considerable gaps in their effectiveness. Online fundraising does not entail a significant financial source. Non-governmental organizations use the internet mainly to build a relationship with their supporters. Online fundraising is therefore seen as a complement to classic fundraising methods that still dominate in case of Czech non-governmental organizations.

The main aim of the Bachelor's thesis "Financial Analysis DENSO Manufacturing Czech, s.r.o." is to conduct a comprehensive financial analysis company Denso Manucfacturing Czech s.r.o. and to assess its financial health in the years 2009 - 2014 and the supplement development of company in the year 2015. The thesis consists of theoretical and practical parts. The theoretical part provides an overview of financial indicators. Among the methods of the financial analysis include horizontal and vertical analysis, ratio analysis , Du pont ROE, bankruptcy and credibility models, analysis of differential indicators, economic value added, intercompany comparison. In the practical part is description of the company and the application of different methods.

The aim of this bachelor's thesis is to assess the economic development and financial situation of the company RUDOLF JELÍNEK, a. s., in the years 2010-2014, to evaluate the effects of the 2012 methanol scandal on the economy of the company and, based on these results, to identify the company's strengths and weaknesses, threats and opportunities in the field and to give recommendations for the future direction of the company. Methods used include PEST analysis, Porter's five forces model and financial analysis including the analysis of the absolute indicators, distinction indicators and ratios, economic value added, bankruptcy and credibility models and intercompany comparison. The analyses have been conducted from the point of view of the company's managers, who are responsible for the management of the company. The sources of information used in the thesis have mostly been the company's annual reports, information collected during a personal interview with Mr Miroslav Motyčka, as well as statistical data provided by the Czech Statistical Office and the Ministry of Industry and Trade of the Czech Republic. The conclusion presents the key results of the strategic analysis and relevant recommendations.

The aim of this study was to set up a business that sells specialized sporting goods aimed at extreme sports and analysis of the suitability of operation of the business. We havee defined theoretical concepts such as founding project, strategic analysis, or business in general to create a knowledge base that had been used in the practical part. Using strategic analysis we reviewed surroundings of the company and preparation of all project we created a picture of the business activities and results for the first and second year of operation. This was supplemented optimistic and pessimistic estimates and indicators. In conclusion, we summarize the positive and negative aspects of establishing a business and personal point of view of its benefits.

The diploma thesis includes an economic analysis of Kofola a.s. between 2009 and 2014. The aim of this work is to perform an economic analysis of the company, to assess its financial health and make a comparison with market developments. Own part of the work is divided into two main parts. The first is methodological section which describes used methods and models. In the practical part is applied methods from the theoretical part on observed enterprise. It is mainly based on financial reports. The financial analysis consists of an analysis of absolute indicators and ratios. Furthermore, the practical part contains rules of balance working capital analysis and DuPont analysis of ROE, cost and inventory analysis, comprehensive evaluation of business models and the intercompany comparison. In conclusion there are summarized and evaluated the results of practical part and deduced appropriate recommendations.

Recently we can observe an increasing trend in business and nonprofit collaboration in the Czech Republic. The thesis aims to describe the latest possibilities of this cross-sector collaboration and the research analyses cooperation of companies with NGO Toulcův dvůr, z.s. The research has been carried out in form of two sets of questionnaires (within organizations at Toulcův dvůr and within companies that support these organizations) and in form of semi-structured interviews with leaders of member organizations of Toulcův dvůr, z.s. Lastly the thesis has suggested further recommendation for the future development of the cooperation.

The master thesis identifies basic success factors of non-governmental organizations. Measurable indexes from individual areas of NGO management are evaluated within the selected sample of public benefit organizations. The main attention is dedicated to the areas of strategic and financial management. The thesis uses data from research project - Best practice in non-governmental organizations, in a form of survey by questionnaire together with information from annual reports of individual organizations. The thesis offers an idea on how to obtain the data from NGOs, how to work with them, analyse and evaluate them.

The aim of this Masters thesis is the implementation of the strategic analysis on nongovernmental organization Stará škola, z.s. In first, theoretical part it focuses on the characteristics of the non-profit sector and the methodology used for the strategic analysis. The second part applies this methodology on the organization Stará škola. To analyze the macroenvironment it uses PEST analysis, in the context of microenvironment it focuses on the analysis of competitors, clients and public. This thesis also includes financial analysis, which also focuses on models BAMF and KAMF, which are often used in the context of NGOs. In conclusion, the thesis aims to evaluate the overall status of the organization and list some recommendations for the future.

The aim of the Master´s Thesis is implementation of the strategic analysis for the non-governmental organization OD5K10, z. s., considering the external environment and also the internal resources, which are available for the organization, and in this way reveal all the factors which have impact on its economy. For analysis of the macro-environment PEST analysis is used. In analysis of the micro-environment there are indetified forces, which can affect an ability of the organization to satisfy the needs of its clients (either customers themselves or competitors, suppliers, community). We can not forget also internal analysis, where resources of this subject, its financial management and its reliability are described and analyzed. The important part of the thesis is the synthesis of the results, where strenghts, weaknesses, opportunities and threats are summarized.

This thesis focuses on the strategic analysis of nonprofit organization Bezobalu which is concerned in research in unpackaging in the Czech Republic. The theoretical part first defines the concepts and the main factors that accompanies the nonprofit sector. Further part will focus on the strategic analysis of the organization, namely the analysis of ma-cro, analysis of micro and analysis of enterprise resources. The stated goal is to evaluate all the influences that affect the organization, but also the fact that the organization has influence and benefit from the opportunities. Work should bring a non-profit organi-zation full summary of the processes and outside the organization going.

The goal of the thesis is to provide an economic analysis of Klubíčko Beroun, o.p.s. To be successful, a nongovernmental organizations have to plan with a good strategy and analyze both outer and inner environments. The NGOs receive finances mostly from donors and have to be responsible for using them efficiently. Therefore, NGOs should not undervalue the economic aspect of their activities and should pay attention to the financial indicators. In my work, I focus on the analysis of the strategy and on the financial analysis. The thesis consists of two parts: the theoretical-methodological part, and the analytical part. In the first part, the basic theoretical apparatus is introduced, and it is consequently used in the second part. The results of the analysis of the strategy and the financial analysis serve as a basis for the SWOT analysis and for the formulation of the strategy for Klubíčko Beroun, o.p.s.

This diploma thesis comprehensively analyzes the economic situation of a family-owned business, KK TECHNOING Co., Ltd, between 2010 and 2014. The analysis focuses specifically on quantifying the economic benefits generated for the businesses' owners. The theory of the thesis, including an introduction to the methodological apparatus applied in the analytical portion of the thesis, is presented after the foreword. The analytical portion is located after a short introduction to KK TECHNOING. The practical part of the economic analysis includes a horizontal and vertical analysis of the company's financial statements, ratios parallel system, the DuPont and the Economic value added analysis, creditworthy and bankruptcy models and a business sector comparison. All findings will be summarized and evaluated at the end of the thesis with specific suggestions for company improvement.

The aim of this thesis is to describe and apply selected prediction models as a part of a financial analysis of a Pilsen Steel company, which ended up in a bankruptcy. 15 models are being applied on the Pilsen Steel altogether, 10 bankruptcy (prediction) and 5 creditworthiness. Their development tracks the period between 2007 and 2012. The thesis evaluates the performance of models, comments on their development and examines what influenced them the most. Author presents his subjective opinions and observations about the pros and cons of each model, at the end of the practical part of this thesis.

This Bachelor's Thesis evaluates the economic situation in the public benefit organization Dialog Jessenius. The analysis of the company is conducted by focusing on the fundraising methods which are applied by the company in order to gain necessary resources. The theoretical part covers basic information about the non-profit sector, structure of resources, key fundraising terminology and introduction to the fundraising methods. The practical part includes a detailed description and assessment of the applied fundraising methods. Overall economic situation in the field of fundraising is closely examined using the BCG matrix. The future development of the fundraising methods in the organization is predicted based on the researched data.

The thesis is focused on the analysis of financing of Secondary building school in Třebíč -- Střední škola stavební Třebíč, funded organization, between the years 2009 -- 2013. The theoretical part includes the structure of national economy, then public sector issues, which education is part of it. Followed by sources of financing of secondary school, legal forms of school, tax benefit and method's description. These methods are used in the practical part, starting with horizontal and vertical analysis, after that self-sufficiency, profitability and finished by KAMF* model. There is neither a comparison with other secondary schools missing, operating on the same field as Střední škola stavební Třebíč is. The conclusion of the thesis is the fact that Střední škola stavební Třebíč uses all approachable ways how to reach the finance to raise student's amount.

The goal of this thesis is to construct founding financial project of the company Kino Káva Ltd. The theoretical part presents the basic concepts related to business, strategic and marketing analysis, principles of financial management, pricing, asset and capital structure, tax issues, founding budget and financial indicators which evaluate health of the company. In the practical part is the company presented, followed by an analysis of micro-environment and macro-environment, and then focus on marketing mix. It continues making the founding budget in three variants - realistic, optimistic and pessimistic, always for the first three years of business. The final part evaluates each variant with the use of accounting statements and financial indicators.

The thesis is focused on analyzing the financial resources of the company Dejvické divadlo, o.p.s., in 2004 - 2012. Being a non-profit organization, the theoretical part is focused on the non-profit sector approach and the issues of its funding. Besides stating the most common legal forms of non-profit organizations in the Czech Republic are further elaborated their current options for fundraising. The following section describes methods of analysis used in the practical part. There is also a horizontal and vertical analysis of financial resources, evaluation of self-sufficiency of the company and analysis of performance through model KAMF*. There is not absent the comparison with the subjects in the sphere of influence (especially with the Divadlo Archa, o.p.s.). The analysis shows, that the Dejvické divadlo, o.p.s., was managed to adapt to new conditions after its transformation in 2004 and is managed to fulfill the princip of a multi-source funding.

The aim of the thesis is the analysis of the civil / private non-profit organization with focus on its fundraising, current situation in the non-profit industry as well as a detailed overview of organizations, included in this sector. The paper is divided into a theoretical and research part. The theoretical part, at first, elaborates on non-profit sector, fundraising and its methodology and discusses the legal requirements & regulations in the context of non-profit sector, donors and sponsors. The research part applies the methodology defined in the theoretical part and analyses the operations and fundraising methods of the specific organization chosen for such purpose. The outcomes of the analysis were used to compare the company with a similar firm operating in the given industry in order to draft a possible strategies and improvements regarding the fundraising possibilities.

This bachelor thesis is focused on analyzing the financial, tangible, intangible and human resources of the cultural institution Museum Kampa -- the Jan and Meda Mládek Foundation for the period 2003 - 2012. The theoretical part is focused on the non-profit organizations' approach and the environment of cultural institutions to which category Museum Kampa -- the Jan and Meda Mládek Foundation belongs. The theoretical part describes the legal status of non-profit organizations in the Czech Republic and focuses on the description of the possible resources of the organization and especially on the acquisition of these resources by them. The theoretical part also deals with methods of analysis of the organization's resources, which are then used in the practical part. The practical part is focused on describing the specific financial, tangible, intangible and human resources of the museum and it is also performed in the horizontal and vertical analysis of resources and summary analysis using models BAMF and KAMF *. The work also compares trends in the field of action and contains recommendations for further development of the organization.

The diploma thesis handles economic analysis of the company MD logistika, a.s. The work is divided into theoretical and practical part. The theoretical part describes the indicators of profitability, liquidity, activity, debt, costs and market indicators. DuPont analysis breaking down ROE was used and was followed by a more detailed decomposition of ROA. Within the value indicatiors was used economic value added, which was calculated by two methods. The credibility, bankruptcy and credibility - bankruptcy models were applied to evaluate the company. The operational leverage, financial leverage and more detailed analysis of stocks analysis were performed. In the practical part each procedure, which was elaborated in the theoretical part of company, was applied to the MD logistika, a.s. In the conclusion the company was compared with the closest competitors and the industry averages.

The aim of this bachelor's thesis is to analyze financial situation of the company KRPA PAPER, a. s. from the year 2008 to 2013 using tools of financial analysis and to give information about company's development in the year 2014. This bachelor's thesis consists of four sections. Reasons for creating this bachelor's thesis and its aims are stated in the introduction. Teoretical section describes individual tools and methods of financial analysis used in this thesis. Practical section applies these tools and methods to the inspected company using publicly available information. Conclusion summarizes outcomes of performed financial analysis, evaluates overall situation of inspected company and states suggestions to improve company's situation.

The aim of this thesis is to provide a SWOT analysis of the Via Foundation through which is detected potential opportunities and threats for the organization and its current strengths and weaknesses. The theoretical part explains the basic concepts, theoretical knowledge and the process itself concerning the creation of a SWOT analysis. The described methods are then used in the practical part on the example of the Via Foundation. To identify potential opportunities and threats from the external environment is used PEST analysis supported by time series analysis. For discovering potential of the organization in terms of strengths and weaknesses is used the evaluation of selected parameters of the organization as compared to the analogous organizations. In conclusion, the thesis summarizes important information obtained by this analysis and there are proposed recommendations for the organization.

The aim of this thesis is to analyze the current situation of social entrepreneurship in the Czech Republic. It emphasizes the importance of social economy, the field between the public sector and the private market sector. This thesis is interested in existing companies which consider themselves as "social" and describes their common features. It presents the social companies' founding years, what their legal forms are, their areas of business and why they consider themselves social. This paper also examines social entrepreneurship in an international context, it endeavours to identify where and how the Czech Republic could inspire itself to improve. Social entrepreneurship in Ireland is analyzed in detail according to the same criteria as social entrepreneurship in the Czech Republic. The purpose of this work is to create an overview of social entrepreneurship.

The diploma thesis focus on elaboration of economic analysis of company Mlékárna Hlinsko, a. s. The thesis includes the basic characteristics of the industries in which the company operates, including the composition of Porter's five forces model. In the thesis are used profitability ratios, leverage, activity, liquidity and capital market. At the same time, it analyzes the degree of operating leverage and impact assessment of financial leverage. To determine the incremental impact on the return on equity is used Du Pont decomposition. As part of a comprehensive evaluation were applied credibility and bankruptcy models - Altman model, Index IN05 and Index bonity. Company Mlékárna Hlinsko, a. s. was compared with relevant competitors in the market and industry averages. In conclusion of the thesis were drawn appropriate advices and recommendations for the future. The thesis is drawn up with regard to the specifics of the food industry and the connection with company Agrofert, a. s.

The aim of this Master's thesis is to carry out an economic analysis of the company VAFO PRAHA, s.r.o. in the period of 2007 - 2013. The thesis is divided into four sections - introduction, theoretical-methodological part, practical part, and conclusion. The introduction defines the goal and explained the reason for the choice of the topic. The theoretical and methodological part determines the methodology, which is applied in the practical part. During the analysis, I will use indicators like indicators of activity, and profitability. Financial health is assessed using creditworthy and bankruptcy models. The analyzed company is also compared with the industry results. In conclusion, I will summarize the results achieved and suggest recommendations.

The subject of this diploma thesis on topic "Economic analysis of the chosen company" is the assessment of the economic performance of MOIRA CZ, a.s. The aim of this thesis is to evaluate the situation assess with respect to its financial health, economic performance and future viability. The first part of my thesis is devoted to approaches to economic analysis and its methods, in the second part is analysed the economic situation of the chosen company. The starting point for practical part are financial statements and their analysis using horizontal and vertical analysis, analysis of relative and financial ratios, or creditworthy and bankruptcy models. Further the DuPont analysis and analysis of he Economic Value Added (EVA) are applied. In conclusion are summarized the results of economic analysis and set out proposals for action that could lead to increased economic performance of the company.

The barchelor's thesis is focused on analysing of financing of non-profit organisation. The theoretical part describes basic terms, issues and options for financing of non-profit organisation. The thesis is also focused on legal forms and changes, which are related to the New Civil Code. The practical part describes activities and fundings of Audabiac o.s. for the time period of 2009 -- 2012. In the conclusion of this barchelor's thesis is Audabiac o.s. evaluated by the Analysis of reliability of non-profit organisation ASNO14.

This thesis focus on strategic analysis of NGO. The first part describes theoretical strategic tools that are used in the second part to analyse specific organization. The organization is called Junák-svaz skautů a skautek ČR and it is a scout organization of the Czech Republic. It is the biggest Czech organization that provides leisure time activities for children and young people. The aim of this thesis is to analyse its position on the market of leisure activities and to indicate possibilities of its future development.