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2. Comparative Analysis of Surgical and Endovascular Approaches for Isolated Aortic Coarctation Repair across Age Groups: Outcomes and Long-Term Efficacy.

Author

Dikmen, Nur, Ozcinar, Evren, Eyileten, Zeynep, Hasde, Ali Ihsan, Yazicioglu, Levent, Kaya, Bulent, and Uysalel, Adnan

Subjects
SURGICAL anastomosis, ENDOVASCULAR surgery, AORTIC coarctation, ELECTRONIC health records, BLOOD pressure, OPERATIVE surgery
Abstract

Background: Aortic coarctation, a condition characterized by localized narrowing of the aorta, can be managed with either surgical or endovascular techniques. This study aims to compare these approaches concerning long-term outcomes, particularly re-coarctation rates and late arterial hypertension. Methods: We retrospectively analyzed data from patients with native, isolated aortic coarctation treated by surgical or endovascular methods between 2015 and 2024. Clinical and demographic data were collected from electronic health records. Blood pressure was measured using oscillometric devices, and transthoracic echocardiography (TTE) was performed by an experienced sonographer. The primary endpoint was to identify which treatment predicted re-coarctation during follow-up, while the secondary endpoint assessed the incidence of late arterial hypertension. Results: Sixty-nine patients were included, with a mean age of 18.14 ± 8.18 years (median 16 years; range 8 to 37 years) and a median follow-up of 3 years (range 6 months to 8 years). Of these, 67 (97.1%) underwent elective repairs. Repair techniques included endovascular treatment (24.6%), surgical end-to-end anastomosis (47.8%), and surgical patchplasty (27.5%). The endovascular group was significantly older (29.82 ± 5.9 years vs. 14.33 ± 4.25 years, p = 0.056) and had shorter procedure durations and hospital stays. One-year freedom from reintervention was significantly higher in the surgical group (98.7%) compared to the endovascular group (88.23%) (p < 0.001). Conclusions: Both techniques effectively treat aortic coarctation, but surgical repair offers better long-term outcomes, while endovascular repair provides shorter recovery times. These findings should inform the choice of treatment modality based on patient-specific factors and clinical priorities. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Evaluation of the Performance of Vasoactive Ventilation Renal Score in Predicting the Duration of Mechanical Ventilation and Intensive Care Hospitalization After Pediatric Cardiac Surgery

Author

Havan, Merve, primary, Emekli, Burak, additional, Özcan, Serhan, additional, Gün, Emrah, additional, Botan, Edin, additional, Ramoğlu, Mehmet, additional, Karagözlü, Selen, additional, Dikmen, Nur, additional, Erdoğan, Beyza Doğanay, additional, Uçar, Tayfun, additional, Eyileten, Zeynep, additional, Tutar, Ercan, additional, Uysalel, Adnan, additional, and Kendirli, Tanıl, additional

Published
2022
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19. The efficacies of modified mechanical post conditioning on myocardial protection for patients undergoing coronary artery bypass grafting

Author

Durdu Serkan, Sirlak Mustafa, Cetintas Demir, Inan Mustafa, Eryılmaz Sadik, Ozcinar Evren, Yazicioglu Levent, Elhan Atilla, Akar Ahmet, and Uysalel Adnan

Subjects
Cardiopulmonary bypass, Myocardial protection, Ischemia-reperfusion injury, Coronary artery bypass grafting, Post-conditioning, Surgery, RD1-811, Anesthesiology, RD78.3-87.3
Abstract

Abstract Background Coronary artery bypass grafting (CABG) with cardioplegic cardiac arrest and cardiopulmonary bypass (CPB) is associated with myocardial injury. The aim of this study was to investigate whether a modified mechanical post-conditioning (MMPOC) technique has a myocardial protective effect by enhancing early metabolic recovery of the heart following revascularization. Methods A prospective, randomized trial was conducted at a single-center university hospital performing adult cardiac surgery. Seventy-nine adult patients undergoing first-time elective isolated multivessel coronary artery bypass grafting were prospectively randomized to MMPOC or control group. Anesthetic, cardiopulmonary bypass, myocardial protection, and surgical techniques were standardized. The post reperfusion cardiac indices, inotrope use and biochemical-electrocardiographic evidence of myocardial injury were recorded. The incidence of postoperative complications was recorded prospectively. Results Operative characteristics, including CPB and aortic cross-clamp time, were similar between the two groups (p>0.05). The MMPOC group had lower troponin I and other cardiac biomarkers level post CPB and postoperatively, with greater improvement in cardiac indices (p Conclusions MMPOC technique promotes early metabolic recovery of the heart during elective CABG, leading to better myocardial protection and functional recovery.

Published
2012
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24. Residual Obstruction Detected During Pregnancy 28 Years After Total Correction of Tetralogy of Fallot and Its Surgical Treatment

Author

TAŞAR, Mehmet, EYİLETEN, Zeynep, Dikmen Yaman, Nur, İSMAİL, Murat, SAYIN, Tamer, and UYSALEL, Adnan

Subjects
Fallot tetralojisi,ventrikül çıkım yolu obstrüksiyonu,yeniden ameliyat, Medicine, Tetralogy of Fallot,ventricular outflow obstruction,reoperation, Tıp
Abstract

Fallottetralojisi (TOF) tüm siyanotik kalp hastalıkları arasında en sık görülendefekttir. Patofizyolojisi iyi bilinmektedir. Tam düzeltmeameliyatlarının sonuçları yüzgüldürücü olmakla birlikte,bazı özel durumlarda palyatifşant girişimlerine gereksinim olmaktadır. Tam düzeltme ameliyatlarının yaygınuygulamasına rağmen uzun dönemde gelişen rezidüel darlık sorun olabilmektedir.Uygun tedavinin seçilmesi için doğru tanı şarttır. Kardiyak manyetik rezonansgörüntüleme doğuştan kalp defekti hakkında güvenilir ve kapsamlı bilgisağlayabilmektedir. Bu yazıda, çocukluk döneminde TOF nedeniyle tam düzeltmeameliyatı yapılmış bir kadın hastada 28 yıl sonra gebelik sırasında saptanan veyeniden ameliyatla tedavi edilen sağ ventrikül çıkım yolu darlığı sunuldu., Tetralogy of Fallot (TOF) is the most common syanoticheart defect, with well-known pathophysiology. Although total correctionoperations have excellent outcomes, palliative shunt procedures may benecessary in some situations. Despite the common use of total correctionprocedures, residual obstruction may develop in the long-term. Accuratediagnosis is essential for approppriate treatment. Cardiac magnetic resonanceimaging provides reliable and comprehensive information about the nature ofcongenital heart defects. In this case report, we presented a woman whounderwent reoperation for right ventricular outflow tract obstruction detectedduring pregnancy 28 years after total correction surgery of TOF.

Published
2015

27. Surgical Repair of Lower Extremity Vascular Injuries in Children: Two Cases

Author

Tasar, Mehmet, Yaman, Nur Dikmen, Saricaoglu, Cahit, Eyileten, Zeynep, Kaya, Bulent, and Uysalel, Adnan

Subjects
Article Subject
Abstract

The use of percutaneous devices is commonplace for the treatment of many congenital heart defects. However, there are some situations where procedure-related complications are encountered and surgical help is required to ameliorate this issue. Vascular injury due to transcatheter intervention is a significant and challenging complication and occasionally requires surgical approach. In this case report, we aimed to present successful surgical management of vascular injuries associated with percutaneous interventions in children.

Published
2014
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36. Native Valve Brucella Endocarditis

Author

Inan, Mustafa Bahadir, primary, Eyileten, Zeynep Bastuzel, additional, Ozcinar, Evren, additional, Yazicioglu, Levent, additional, Sirlak, Mustafa, additional, Eryilmaz, Sadik, additional, Akar, Ruchan, additional, Uysalel, Adnan, additional, Tasoz, Refik, additional, Eren, Neyyir Tuncay, additional, Aral, Atilla, additional, Kaya, Bulent, additional, Ucanok, Kemalettin, additional, Corapcioglu, Tumer, additional, and Ozyurda, Umit, additional

Published
2009
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46. Native Valve Brucella Endocarditis.

Author

Inan, Mustafa Bahadir, Eyileten, Zeynep Bastuzel, Ozcinar, Evren, Yazicioglu, Levent, Sirlak, Mustafa, Eryilmaz, Sadik, Akar, Ruchan, Uysalel, Adnan, Tasoz, Refik, Eren, Neyyir Tuncay, Aral, Atilla, Kaya, Bulent, Ucanok, Kemalettin, Corapcioglu, Tumer, and Ozyurda, Umit

Published
2010
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49. Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.

Author

Taşar, Mehmet, Eyileten, Zeynep, Kasımzade, Ferit, Uçar, Tayfun, Kendirli, Tanıl, and Uysalel, Adnan

Abstract

Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome is a rare autosomal recessive congenital disorder that includes childhood-onset camptodactyly, synovial hyperplasia-related arthropathy, progressive coxa vara deformity and noninflammatory pericarditis. A seven-year-old male patient had a diagnosis of CACP. He had pericardial effusion and underwent surgical tube drainage. CACP syndrome is seen very rarely, and differential diagnosis is very important. CACP is usually treated medically, but surgery may sometimes be preferred, as in our patient. [ABSTRACT FROM AUTHOR]

Published
2015

50. Middle aortic syndrome in a teenager.

Author

Eyileten, Zeynep, Taşar, Mehmet, Yazıcıoğlu, Levent, Kaya, Bülent, Fitöz, Suat, and Uysalel, Adnan

Abstract

Middle aortic syndrome (MAS) is a rare pathology that involves diffuse/ segmental narrowing of the distal thoracic or abdominal aorta. The most common clinical manifestation is severe hypertension, which requires multiple antihypertensive medications and/or surgical repair. We report the surgical repair of MAS in a 14-year-old male. [ABSTRACT FROM AUTHOR]

Published
2015

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