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2. Effect of Magnesium on Ventricular Extrasystoles in Children.

Author

Uysal, Fahrettin, Turkmen, Hasan, Genc, Abdusselam, and Bostan, Ozlem M.

Subjects
*MAGNESIUM, *TREATMENT effectiveness, *AMBULATORY electrocardiography, *DESCRIPTIVE statistics, *ARRHYTHMIA, *DIETARY supplements, *SYMPTOMS, *CHILDREN
Abstract

Magnesium (Mg) is a crucial element for cardiovascular system and its deficiency results in a variety of cardiac arrhythmias. The aim of this study is to determine the effect of oral Mg supplementation on the frequency of ventricular extrasystoles (VES) in children. Magnesium supplementation was given to 42 children who had VES without structural heart disease. Clinical, electrocardiographic, and Holter monitoring studies were reviewed. The mean baseline 24 h VES burden on Holter monitoring was 10.26% ± 4.13% and it was decreased to 6.62% ± 3.88% after. There was no significant difference between the pre-treatment serum Mg levels and the decrease in the frequency of VES. In conclusion, oral Mg therapy was found to be effective at suppressing VES in children regardless of serum Mg levels. Large and randomized studies are needed to demonstrate the effect of magnesium on VES suppression. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Evaluation of Children with Aortic Coarctation: A Single-Center Experience.

Author

Türkmen, Hasan, Uysal, Fahrettin, Genç, Abdüsselam, Bostan, Özlem M., and Siğnak, Işık Şenkaya

Subjects
*TRANSLUMINAL angioplasty, *CONGENITAL heart disease, *RISK assessment, *PEARSON correlation (Statistics), *ACADEMIC medical centers, *T-test (Statistics), *AORTIC coarctation, *QUESTIONNAIRES, *FISHER exact test, *RETROSPECTIVE studies, *MANN Whitney U Test, *DESCRIPTIVE statistics, *TREATMENT effectiveness, *EARLY intervention (Education), *LONGITUDINAL method, *KAPLAN-Meier estimator, *MEDICAL records, *ACQUISITION of data, *DISEASE relapse, *COMPARATIVE studies, *DATA analysis software, *ECHOCARDIOGRAPHY, *PROPORTIONAL hazards models, *DISEASE risk factors
Abstract

Objective: Coarctation of the aorta (CoA) accounts for 3.5% of all congenital heart diseases in children. The clinical manifestations range from heart failure to asymptomatic hypertension. Treatment options include surgical repair, balloon angioplasty, and stenting. We aimed to investigate the long-term results of surgery and balloon angioplasty to identify the possible risk factors for recoarctation and predictors associated with early success in treatment modalities. Materials and Methods: The data of 138 children who underwent examinations at a tertiary center between 2015 and 2020 with the diagnosis of CoA were evaluated. The basic demographic characteristics, clinical and echocardiographic findings, results, and treatment methods of the patients were evaluated retrospectively. Results: The mean follow-up period was 75.1 months (range of 1-223). As initial treatment, 75 patients (60.5%) underwent balloon angioplasty, 44 (35.5%) underwent surgery, and 5 (4%) underwent stenting. The early success rate of balloon angioplasty and surgery was 72.5% and 79.5%, respectively. Recoarctation occurred in 47.6% of patients following the first therapy. The median reintervention-free survival time was 138 months for all patients and was significantly higher in the surgery group (P = .025). The recoarctation rate was slightly lower in the surgery group than in those who underwent balloon angioplasty, but it was not statistically significant. None of the clinical and echocardiographic findings were found to be associated with recoarctation or early success. Conclusion: The rate of recoarctation is still high in long-term follow-up after aortic coarctation treatment, and clinical and echocardiographic findings are insufficient to predict the chance of early success and the risk of recoarctation. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Arterial tortuosity syndrome: 40 new families and literature review

Author

Beyens, Aude, Albuisson, Juliette, Boel, Annekatrien, Al-Essa, Mazen, Al-Manea, Waheed, Bonnet, Damien, Bostan, Ozlem, Boute, Odile, Busa, Tiffany, Canham, Nathalie, Cil, Ergun, Coucke, Paul J., Cousin, Margot A., Dasouki, Majed, De Backer, Julie, De Paepe, Anne, De Schepper, Sofie, De Silva, Deepthi, Devriendt, Koenraad, De Wandele, Inge, Deyle, David R., Dietz, Harry, Dupuis-Girod, Sophie, Fontenot, Eudice, Fischer-Zirnsak, Björn, Gezdirici, Alper, Ghoumid, Jamal, Giuliano, Fabienne, Diéz, Neus Baena, Haider, Mohammed Z., Hardin, Joshua S., Jeunemaitre, Xavier, Klee, Eric W., Kornak, Uwe, Landecho, Manuel F., Legrand, Anne, Loeys, Bart, Lyonnet, Stanislas, Michael, Helen, Moceri, Pamela, Mohammed, Shehla, Muiño-Mosquera, Laura, Nampoothiri, Sheela, Pichler, Karin, Prescott, Katrina, Rajeb, Anna, Ramos-Arroyo, Maria, Rossi, Massimiliano, Salih, Mustafa, Seidahmed, Mohammed Z., Schaefer, Elise, Steichen-Gersdorf, Elisabeth, Temel, Sehime, Uysal, Fahrettin, Vanhomwegen, Marine, Van Laer, Lut, Van Maldergem, Lionel, Warner, David, Willaert, Andy, Collins, Tom R., Taylor, Andrea, Davis, Elaine C., Zarate, Yuri, and Callewaert, Bert

Published
2018
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7. Does Post-COVID-19 Erectile Dysfunction Improve over Time?

Author

Gök, Alper, Altan, Mehmet, Doğan, Ahmet Emin, Eraslan, Aşır, Uysal, Fahrettin Şamil, Öztürk, Ufuk, Saguner, Ardan Muammer; https://orcid.org/0000-0003-1896-0803, İmamoğlu, Muhammet Abdurrahim, Gök, Alper, Altan, Mehmet, Doğan, Ahmet Emin, Eraslan, Aşır, Uysal, Fahrettin Şamil, Öztürk, Ufuk, Saguner, Ardan Muammer; https://orcid.org/0000-0003-1896-0803, and İmamoğlu, Muhammet Abdurrahim

Abstract

BACKGROUND Some studies have shown that there may be an increase in the frequency of erectile dysfunction after COVID-19. However, no long-term study has investigated whether this is permanent or temporary. In this study, we aimed to examine whether there was an increase in the frequency of erectile dysfunction among individuals with a history of COVID-19, and, if there was, whether their condition improved over time. MATERIALS AND METHODS In this study, a total of 125 healthy male healthcare workers, 95 with and 30 without a history of COVID-19, were evaluated in terms of erectile function. Four study groups were formed. The first three groups consisted of individuals with a history of COVID-19 confirmed by the polymerase chain reaction (PCR) test at different times, who recovered from the disease (time elapsed since COVID-19 positivity: <6 months for Group 1, 6 to 12 months for Group 2, and >12 months for Group 3). The individuals in Group 4 did not have a history of COVID-19 diagnosis. In order to evaluate the erectile function of the participants, they were asked to complete the five-item International Index of Erectile Function questionnaire (IIEF-5). Then, statistical analyses were performed to evaluate whether there was a difference between the groups in terms of the IIEF-5 scores. RESULTS There was a statistically significant difference between the groups in terms of the IIEF-5 scores (p < 0.001), and this difference was determined to be caused by the significantly higher IIEF-5 scores of Groups 3 and 4 compared to Group 1 (p = 0.004 and p < 0.001, respectively). In addition, the IIEF-5 score of Group 4 was statistically significantly higher than that of Group 2 (p < 0.001). However, the IIEF-5 scores did not statistically significantly differ between Groups 1 and 2, Groups 2 and 3, and Groups 3 and 4 (p > 0.999, p = 0.204, and p = 0.592, respectively). CONCLUSION There may be deterioration in erectile function after COVID-19; however, this tends to improve

Published
2023

12. Correction: Arterial tortuosity syndrome: 40 new families and literature review

Author

Beyens, Aude, Albuisson, Juliette, Boel, Annekatrien, Al-Essa, Mazen, Al-Manea, Waheed, Bonnet, Damien, Bostan, Ozlem, Boute, Odile, Busa, Tiffany, Canham, Nathalie, Cil, Ergun, Coucke, Paul J., Cousin, Margot A., Dasouki, Majed, De Backer, Julie, De Paepe, Anne, De Schepper, Sofie, De Silva, Deepthi, Devriendt, Koenraad, De Wandele, Inge, Deyle, David R., Dietz, Harry, Dupuis-Girod, Sophie, Fontenot, Eudice, Fischer-Zirnsak, Björn, Gezdirici, Alper, Ghoumid, Jamal, Giuliano, Fabienne, Baena, Neus, Haider, Mohammed Z., Hardin, Joshua S., Jeunemaitre, Xavier, Klee, Eric W., Kornak, Uwe, Landecho, Manuel F., Legrand, Anne, Loeys, Bart, Lyonnet, Stanislas, Michael, Helen, Moceri, Pamela, Mohammed, Shehla, Muiño-Mosquera, Laura, Nampoothiri, Sheela, Pichler, Karin, Prescott, Katrina, Rajeb, Anna, Ramos-Arroyo, Maria, Rossi, Massimiliano, Salih, Mustafa, Seidahmed, Mohammed Z., Schaefer, Elise, Steichen-Gersdorf, Elisabeth, Temel, Sehime, Uysal, Fahrettin, Vanhomwegen, Marine, Van Laer, Lut, Van Maldergem, Lionel, Warner, David, Willaert, Andy, Collins II, Tom R., Taylor, Andrea, Davis, Elaine C., Zarate, Yuri, and Callewaert, Bert

Published
2019
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13. Ventricular Extrasystole in Children: Single-Center Experience.

Author

Uysal, Fahrettin, Özalp, Şule, Genç, Abdüsselam, Akça, Tuğberk, Türkmen, Hasan, and Bostan, Özlem M.

Subjects
*DRUG efficacy, *SYNCOPE, *ECHOCARDIOGRAPHY, *AMBULATORY electrocardiography, *EXERCISE tests, *CONVALESCENCE, *CARDIOPULMONARY system, *RETROSPECTIVE studies, *ACQUISITION of data, *MAGNETIC resonance imaging, *MANN Whitney U Test, *ADRENERGIC beta blockers, *DISEASE relapse, *T-test (Statistics), *SYMPTOMS, *MEDICAL records, *ELECTROCARDIOGRAPHY, *DESCRIPTIVE statistics, *CHI-squared test, *ARRHYTHMIA, *DATA analysis software, *DATA analysis, *LONGITUDINAL method, *CHILDREN
Abstract

Objective: Ventricular extrasystole is one of the most common rhythm disorders in children, and almost all of them are characterized by normal cardiac functions without structural cardiac abnormalities. The aim of this study was to assess the clinical course of ventricular extrasystole in children who did not have cardiac structural abnormalities. Materials and Methods: This retrospective study analyzed 24-hour rhythm Holter recordings performed in our clinic in children. Patients diagnosed with isolated ventricular extrasystole in Holter records and without structural heart disease on echocardiography were included in the evaluation. Results: A total of 20 160 Holter results were evaluated in the study, and 226 patients (male; 66%) met the criteria. The mean follow-up time was 8.7 ± 3.2 years. While 81.8% of the patients were asymptomatic, the most common symptom was palpitation and 5 patients had syncope. Of the patients, 72 (31.8%) received medical therapy. Beta-blockers were the most often prescribed medication. Cardiomyopathy did not develop in any of the patients during the followup period. A partial reduction in the frequency of ventricular extrasystole was observed in 42% of the patients, while complete recovery was observed in 22%. Conclusion: Ventricular extrasystole in children generally has a good prognosis; most of them are asymptomatic, and the rates of spontaneous regression over time are quite high, regardless of the origin. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Rare Primary Signet Ring Cell Carcinoma of the Bladder Cancer.

Author

Sarı, Hilmi, Uysal, Fahrettin Şamil, Ekenci, Berk Yasin, Bozpınar, Simay, Çimen, Sertaç, and İmamoğlu, Muhammet Abdurrahim

Subjects
ANTIBIOTICS, ADENOCARCINOMA, BLADDER tumors, URINARY organs, DYSURIA, RARE diseases
Abstract

Primary signet ring cell carcinoma of the bladder is a rare tumor and it has a poor prognosis and is more mortal than the urothelial cell carnioma. However, most patients apply with painless macroscopic hematuria; rarely do they could apply with urinary tract infection or lower urinary tract symptoms. In this study; a 47-yearold male was referred to our clinic with dysuria, which was antibiotic therapy and symptomatic treatment. In ultrasonography, bladder wall thickening has been seen then patient underwent with cystoscopy. After atypical lesions were seen on the bladder mucosa, random punch biopsies were taken. A pathological examination revealed infiltrative urothelial carcinoma with a poorly differentiated signet ring cell component. As in this case report, patients with signet ring cell bladder cancer, which is rare and has an aggressive course, might only present with non-specific complaints such as dysuria. If atypical lesions are observed during the diagnostic cystoscopy procedure, the threshold should be kept low to decide on biopsy. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Non-transecting urethroplasty in patients with bulbar urethral strictures shorter than three centimeters.

Author

Yılmaz, Muhammet Şahin, Kokurcan, Alihan, Uysal, Fahrettin Şamil, Özenç, Görkem, and Yalçınkaya, Fatih

Subjects
URETHRA stricture, URETHROPLASTY, SURGICAL complications, SURGICAL clinics, AGE groups, HEALTH facilities
Abstract

This study aimed to compare the success and postoperative complication rates of the novel non-transecting urethroplasty (NTU) technique and conventional excision-primary anastomosis (EPA) in the surgical treatment of short bulbar urethral strictures. Data of the patients who underwent excision-primary anastomosis or NTU procedures at our center for the surgical treatment of bulbar urethral strictures shorter than 3 cm between January 2010 and December 2018 were retrospectively reviewed. Forty-seven patients fulfilled the eligibility criteria for this study. Among these patients, 22 underwent NTU procedure while 25 underwent EPA. There was no difference between the two groups regarding age, stricture length, etiology, past surgical history, and duration of follow-up. The surgical success rates were 88% and 87,2% in the NTU and EPA groups, respectively (p = 0,603). The complication rates were 12% and 13,6% in NTU and EPA groups, respectively. Two groups were similar concerning complication rates (p = 0,603). The novel NTU and conventional EPA techniques are similar regarding surgical success and complication rates in the surgical treatment of bulbar urethral strictures shorter than three centimeters. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Effects of levetiracetam treatment on autonomic nervous system functions in pediatric epilepsy patients.

Author

Direk, Meltem Çobanoğulları, Epcacan, Serdar, Özdemir, Asena Ayca, Uysal, Fahrettin, and Okuyaz, Çetin

Subjects
AUTONOMIC nervous system physiology, INTRAVENOUS therapy, HETEROCYCLIC compounds, EPILEPSY, PEDIATRICS, HEART beat, DESCRIPTIVE statistics, ELECTROCARDIOGRAPHY, ARRHYTHMIA
Abstract

Background: This study investigated the effects of levetiracetam (LEV) treatment on cardiac rhythm and heart rate variability. Methods: The study included two groups of patients diagnosed with non‐lesional epilepsy who had not yet been treated and who presented to the outpatient pediatric neurology clinic at Van Training and Research Hospital, Van, Turkey, between 2019 and 2020. The heart rate variability (HRV) of 47 patients in the first group, before and at the 3rd month of treatment, and intravenous (IV) LEV loading in 13 patients in the second group was evaluated by Holter electrocardiography (ECG). Results: It was determined that the values of triangular index, standard deviation of the RR intervals over a 24‐hour period (SDNN), standard deviation of all 5‐minute mean RR intervals (SDANN), mean of standard deviations of all normal RR intervals (SDNNI), the percentage of RR intervals with >50‐millisecond variation (PNN50), and the square root of mean squared differences of successive RR intervals (RMSSD). HRV of 47 patients under LEV treatment significantly increased in the 3rd month of treatment compared to baseline (p < 0.05). No difference was found in HRV between the intravenous loading and the control group (p > 0.05). Conclusions: Our study suggests that the sympathovagal balance before treatment in the patient group is in favor of the sympathetic nervous system and that the sympathovagal imbalance improves after treatment. Our results show that LEV monotherapy and loading have no negative effect on HRV and potential cardiac arrhythmia risk in children with epilepsy. [ABSTRACT FROM AUTHOR]

Published
2023
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25. ALGORITHMS FROM SYMPTOMS TO DIAGNOSIS IN CHILDREN, EXTENDED AND UPDATED 2nd EDITION

Author

ÇİL, Ergün, BOSTAN, Özlem Mehtap, EREN, Erdal, and UYSAL, Fahrettin

Subjects
Ophthalmology, Göz Hastalıkları, book,children,algorithms,diagnosis
Abstract

The first edition of the book "ALGORITHMS FROM SYMPTOMS TO DIAGNOSIS IN CHILDREN" attracted great interest despite all adverse conditions such as the pandemic, and the "EXTENDED AND UPDATED 2nd EDITION" was published immediately

Published
2021

32. Correction: Arterial tortuosity syndrome: 40 new families and literature review

Author

Beyens, Aude, primary, Albuisson, Juliette, additional, Boel, Annekatrien, additional, Al-Essa, Mazen, additional, Al-Manea, Waheed, additional, Bonnet, Damien, additional, Bostan, Ozlem, additional, Boute, Odile, additional, Busa, Tiffany, additional, Canham, Nathalie, additional, Cil, Ergun, additional, Coucke, Paul J., additional, Cousin, Margot A., additional, Dasouki, Majed, additional, De Backer, Julie, additional, De Paepe, Anne, additional, De Schepper, Sofie, additional, De Silva, Deepthi, additional, Devriendt, Koenraad, additional, De Wandele, Inge, additional, Deyle, David R., additional, Dietz, Harry, additional, Dupuis-Girod, Sophie, additional, Fontenot, Eudice, additional, Fischer-Zirnsak, Björn, additional, Gezdirici, Alper, additional, Ghoumid, Jamal, additional, Giuliano, Fabienne, additional, Baena, Neus, additional, Haider, Mohammed Z., additional, Hardin, Joshua S., additional, Jeunemaitre, Xavier, additional, Klee, Eric W., additional, Kornak, Uwe, additional, Landecho, Manuel F., additional, Legrand, Anne, additional, Loeys, Bart, additional, Lyonnet, Stanislas, additional, Michael, Helen, additional, Moceri, Pamela, additional, Mohammed, Shehla, additional, Muiño-Mosquera, Laura, additional, Nampoothiri, Sheela, additional, Pichler, Karin, additional, Prescott, Katrina, additional, Rajeb, Anna, additional, Ramos-Arroyo, Maria, additional, Rossi, Massimiliano, additional, Salih, Mustafa, additional, Seidahmed, Mohammed Z., additional, Schaefer, Elise, additional, Steichen-Gersdorf, Elisabeth, additional, Temel, Sehime, additional, Uysal, Fahrettin, additional, Vanhomwegen, Marine, additional, Van Laer, Lut, additional, Van Maldergem, Lionel, additional, Warner, David, additional, Willaert, Andy, additional, Collins II, Tom R., additional, Taylor, Andrea, additional, Davis, Elaine C., additional, Zarate, Yuri, additional, and Callewaert, Bert, additional

Published
2018
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36. Erken taburcu olan yenidoğanlarda yeniden hastaneye yatış nedenleri ve sonuçları Orijinal Araştırma

Author

Akın, Mustafa Ali, Kavuncuoğlu, Sultan, Özbek, Sibel, GÖK, Esin Yıldız, Uysal, Fahrettin, Güler, Serhat, and ÖZTÜRK, Erkut

Subjects
erken taburcu olma,hiperbilirubinemi,hiperfenilalaninemi,yeniden hastaneye yatış,yenidoğan
Abstract

Aim: Rehospitalization and serious morbidities resulting from early discharge in the 1990 s were questioned In this study our aim was to investigate the frequency of rehospitalization outcomes and morbidities of the early discharged newborns and to identify the recall rate and if there were any missed cases in hyperphenylalaninemia screening in our unit at which 20 000 25 000 deliveries occur each year Material and Method: Term babies born in 2004 and discharged early according to the ACOG American Comity of Obstetrics and Gynecology criteria were included in this study Rehospitalization criteria was defined as hyperbilirubinemia levels close to exchange limits hypernatremic dehydration ductus dependent congenital heart diseases Recall rate and possible missed diagnosis for hyperphenylalaninemia due to early discharge were investigated Results: 444 term newborns of 20 813 live births delivered in our hospital during 2004 were hospitalized following the labor while 2 950 of them were rehospitalized afterdischarge for several problems 111 patients out of 2 950 cases were included in the study and 87 of them had hyperbilirubinemia 7 2 hypernatremic dehydration and 5 4 ductus dependent congenital heart disease Among all cases 86 werere rehospitalized in the first 7 days and 14 between the 8th to 28th nbsp; days According to hyperphenylalaninemia screening results recall rate was 0 1 for early discharged term infants and there were no cases missed for diagnosis Conclusıons: The rehospitalization rate in our unit was 15 while it was 3 8 nbsp; among newborns in the study group The most frequent rehospitalization indication was hyperbilirubinemia followed by hypernatremic dehydration as the second Mortality rate was high in the ductus dependent congenital hearth disease 33 and there were not any case of hyperphenylalaninemia missed for diagnosis Keywords: early discharged hyperbilirubinemia hyperphenylalaninemia newborn rehospitalization, Amaç: Dünyada 1990 lı yıllarda başlayan erken taburcu olma bunun sonucu nbsp; yenidoğanın tekrar hastaneye yatışı nbsp; ve ciddi morbiditeleri sorgulanmıştır Bu çalışmada amacımız; yılda 20 000 25 000 canlı doğumu gerçekleştiren merkezimizde erken taburcu olma nedeniyle tekrar yatırılan zamanında doğmuş yenidoğanların yatış sıklığını morbiditelerini ve sonuçlarını belirlemek nbsp; hiperfenilalaninemi taramasında geri çağırma oranları ile atlanan olgu olup olmadığını irdelemektir Gereç ve Yöntem: 2004 yılı içinde The American College of Obstetricians and Gynecologists ACOG ölçütlerine göre erken nbsp; taburcu edilen term nbsp; bebekler nbsp; çalışmaya alındı Yeniden yatış nedeni olarak kan değişim sınırına yakın hiperbilirübinemi hipernatremik dehidratasyon duktus arteriyozusa bağımlı Doğuştan Kalp Hastalığı DKH varlığı ölçüt olarak alındı Hiperfenilalaninemi taramasında erken taburcu edilip geri çağrılan tanısı atlanan hasta varlığı araştırıldı Bulgular: Hastanemizde 2004 yılı içinde doğan 20 813 bebekten 444 term yenidoğan doğumu takiben 2 950 si ise taburcu edildikten sonraki günlerde değişik sorunlar nedeniyle birimimize yatırıldı 2 950 olgunun içinden çalışma kapsamına nbsp; giren 111 hasta değerlendirildiğinde 87 si hiperbilirübinemi 7 2 si hipernatremik dehidatasyon 5 4 ü duktusa bağımlı DKH tanısı aldı Tüm olguların 86 sı ilk 7 günde 14 ü ise 8 28 günde yatırıldı Erken taburcu edilen zamanında doğmuş nbsp; yenidoğanlarda hiperfenilalaninemi taraması sonucu 2004 yılında geri çağırma oranı 0 1 olup tanısı atlanan olgu yoktu Çıkarımlar: Ünitemizin geri yatış oranı 15 olup çalışma kapsamına giren grupta sıklık 3 8 idi En sık yatış nedeni hiperbilirübinemi ikinci sırada hipernatremik dehidratasyondu Duktusa bağlı DKH da ölüm oranı 33 yüksek idi Atlanmış hiperfenilalaninemili olgu saptanmadı Anahtar kelimeler: erken taburcu olma hiperbilirubinemi hiperfenilalaninemi yeniden hastaneye yatış yenidoğan nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; SummaryAim: Rehospitalization and serious morbidities resulting from early discharge in the 1990 s were questioned In this study our aim was to investigate the frequency of rehospitalization outcomes and morbidities of the early discharged newborns and to identify the recall rate and if there were any missed cases in hyperphenylalaninemia screening in our unit at which 20 000 25 000 deliveries occur each year Material and Method: Term babies born in 2004 and discharged early according to the ACOG American Comity of Obstetrics and Gynecology criteria were included in this study Rehospitalization criteria was defined as hyperbilirubinemia levels close to exchange limits hypernatremic dehydration ductus dependent congenital heart diseases Recall rate and possible missed diagnosis for hyperphenylalaninemia due to early discharge were investigated Results: 444 term newborns of 20 813 live births delivered in our hospital during 2004 were hospitalized following the labor while 2 950 of them were rehospitalized afterdischarge for several problems 111 patients out of 2 950 cases were included in the study and 87 of them had hyperbilirubinemia 7 2 hypernatremic dehydration and 5 4 ductus dependent congenital heart disease Among all cases 86 werere rehospitalized in the first 7 days and 14 between the 8th to 28th nbsp; days According to hyperphenylalaninemia screening results recall rate was 0 1 for early discharged term infants and there were no cases missed for diagnosis Conclusıons: The rehospitalization rate in our unit was 15 while it was 3 8 nbsp; among newborns in the study group The most frequent rehospitalization indication was hyperbilirubinemia followed by hypernatremic dehydration as the second Mortality rate was high in the ductus dependent congenital hearth disease 33 and there were not any case of hyperphenylalaninemia missed for diagnosis Keywords: early discharged hyperbilirubinemia hyperphenylalaninemia newborn rehospitalization

Published
2014

37. A newborn with hydrops fetalis diagnosed antenatally Case of the Month

Author

GÖK, Esin Yıldız, Altuncu, Emel, KARABULUT, Muhammed, KAVUNCUOĞLU, Sultan, UYSAL, Fahrettin, and ARSLAN, Hilal Serap

Abstract

Olgu, Cystic fibrosis and alpha 1 antitrypsin deficiency are two important autosomal recessive multi organ diseases They are complex and severe diseases that involve various organs including pancreas Pancreatic disease in cystic fibrosis varies from complete loss of exocrine and endocrine functions to nearly normal pancreatic function A strong correlation between genotype and phenotype is recognized Pancreatic involvement is characterized by malabsorption of fat and protein and growth failure Fat malabsorption leads to special problems with the fat soluble vitamins Enzyme and fat soluble vitamin replacements are the milestones of the malabsorption treatment Gene therapy offers the best hope for a cure of cystic fibrosis Although an association between alpha1 antitrypsin deficiency and chronic pancreatitis has been reported in several case reports in prospective studies it has been shown that pancreatitis prevalence in patients with alpha1 antitrypsin deficiency was not different from that of healthy controls Thus it was concluded that alpha 1 antitrypsin deficiency was not related to the pathogenesis of idiopathic or hereditary chronic pancreatitis However protective role of alpha 1 antitrypsin against pancreatic auto digestion suggests that the deficiency of that protein may worsen the pancreatic disease rather than causing it Early detection and management of pancreatic insufficiency is essential to optimize health and outcomes in cystic fibrosis and alpha 1 antitrypsin deficiency patients Turk Arch Ped 2009; 44: 7 11 Key words: Alfa 1 antitripsin deficinecy cystic fibrosis pancreas

Published
2014

38. Sağlıklı çocuklarda triküspit anüler düzlem sistolik hareketinin normal değerlerinin belirlenmesi

Author

Uysal, Fahrettin, Bostan, Özlem Mehtap, and Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı

Subjects
Healthy people, Ventricular function-right, Systole, Tricuspid valve, Reference standards, Children, Ventricular function, Çocuk Sağlığı ve Hastalıkları, Child Health and Diseases
Abstract

Giriş ve amaç: Triküspit anüler düzlem sistolik hareketi (TAPSE) sağ ventrikül sistolik fonksiyonlarını değerlendirmede kullanılan ekokardiyografik bir ölçümdür. Erişkinlerde normal TAPSE değerleri belirlenmişken çocuklarda referans aralıklarla ilgili yapılan çalışma sayısı yeterli değildir. Bu çalışmada ülkemizdeki sağlıklı çocukların referans TAPSE değerlerinin belirlenmesi amaçlanmıştırYöntem ve gereç: Çalışmada polikliniğimize üfürüm nedeni ile yönlendirilen, yaşları 0-18 arasında değişen 670 sağlıklı çocuk değerlendirildi. Kardiyak problemi olanlar veya başka bir hastalığı olanlar çalışmaya dahil edilmedi. TAPSE ölçümü M-mod ekokardiyografi tekniği kullanılarak ölçüldü. Çocuklarda yaş ve yüzey alanının TAPSE ile ilişkisi araştırıldı.Bulgular: Ortalama TAPSE değerleri 19,96±5,49 bulundu. Kız ve erkek çocuklar arasında TAPSE değerleri açısından anlamlı bir fark saptanmadı. Artan yaş ve yüzey alanı ile beraber TAPSE değerlerinin arttığı tespit edildi. Ortalama TAPSE değeri yenidoğan yaş grubunda 9±1,35 iken 13-18 yaş grubunda 26,27±3,37 bulundu. Çalışmada kalp hızı ile TAPSE arasında ise negatif korelasyon olduğu tespit edildi.Sonuç: Bu çalışmada ülkemizde sağlıklı çocuklarda TAPSE değerlerinin normal aralıkları persantil tablolar oluşturularak sunuldu. Bu referans değerler çocuklarda sağ ventrikül sistolik fonksiyonlarını değerlendirmek için günlük pratikte yol gösterici olabilir.Anahtar kelimeler: TAPSE, referans değerler, sağlıklı çocuklar, sağ ventrikül sistolik fonksiyonu Introduction and objectives: Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measure that allows us to assess right ventricular systolic function. Although normal values are available in adults, there are not enough studies for references of TAPSE in children. Our objective was to establish reference values for TAPSE in our country.Methods and materials: This study included 670 healthy children (age range, 0 to 18 years) referred to our out-patient department for assessment of cardiac murmur. Patients with confirmed cardiac or any other disease were excluded. TAPSE was measured using M-mode echocardiography. The correlation between ages and body surface areas in children and TAPSE values were investigated. Results: Mean TAPSE values were 19,96±5,49. There was no significant differences in TAPSE values between female or male children. TAPSE values increased by the increasing age and body surface area. TAPSE ranged from a mean of 9±1,35 in neonates to 26,27±3,37 in 13-18 years age group. There was found to be a negative correlation between TAPSE values and heart rate in the study.Conclusion: Normal values of healthy children for TAPSE in our country were presented as percentile charts in this study. These reference values could guide the clinicians to evaluate the systolic functions of right ventricle in children in daily practice. Key words: TAPSE, reference values, healthy children, right ventricle systolic function 56

Published
2014

44. Outcomes of Kawasaki Disease

Author

Uysal, Fahrettin, primary, Bostan, Ozlem Mehtap, additional, Celebi, Solmaz, additional, Uysal, Berfin, additional, Hamitoglu, Serif, additional, and Cil, Ergun, additional

Published
2014
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48. Determination of reference values for tricuspid annular plane systolic excursion in healthy Turkish children.

Author

Uysal, Fahrettin, Bostan, Özlem Mehtap, and Çil, Ergun

Subjects
*CARDIAC contraction, *ECHOCARDIOGRAPH research, *CHILDREN'S health, *CHILDREN, *HEART failure
Abstract

Objective: Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement used for evaluating right ventricular systolic function. While established reference values of TAPSE exist for the adult population, only a limited number of studies have attempted to evaluate reference values for the pediatric population. The aim of the present study was to determine the reference values for TAPSE in healthy children in Turkey. Methods: A total of 765 healthy children aged between 0 and 18 years, all of whom were referred to our clinic with cardiac murmurs, were evaluated prospectively. Patients with no cardiac pathologies or other disorders were excluded from the study. The measurement of TAPSE was obtained using a 2D-guided M-mode technique with echocardiography, and the relationship between age and surface area with TAPSE was investigated. The statistical analysis was carried out using the SPSS 20.0 software package (SPSS Inc., Chicago, IL, USA, 2012). Results: The mean TAPSE value was found to be 19.56±5.54mm, and no significant difference was identified between male and female children. TAPSE values showed a positive correlation with increasing age and surface area. The mean TAPSE value was 9.09±1.36 mm in newborns and 25.91±3.60 mm in the 13-18 years age group. A negative correlation was seen between TAPSE and heart rate. Conclusion: In the present study, the reference values for TAPSE in healthy Turkish children were presented in percentile tables and the corresponding z-scores were determined. These reference values may be useful in daily practice for the evaluation of right ventricular systolic function in children. [ABSTRACT FROM AUTHOR]

Published
2016
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49. Yenidoğan Yoğun Bakım Ünitemizde İzlenen Konjenital Kalp Hastalıkları: Sıklığı, Risk Faktörleri ve Prognoz.

Author

Varal, İpek Güney, Köksal, Nilgün, Özkan, Hilal, Bostan, Özlem, Sığınak, Işık Şenkaya, Bağcı, Onur, Doğan, Pelin, and Uysal, Fahrettin

Abstract

Copyright of Journal of Current Pediatrics / Guncel Pediatri is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2015
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50. Yenidoğan Döneminde Tüberoskleroz Tanısı Konulan İki Olgu.

Author

Varal, İpek Guney, Köksal, Nilgün, Özkan, Hilal, Bostan, Özlem, Bağcı, Onur, Uysal, Fahrettin, Yazıcı, Zeynep, and Doğan, Pelin

Abstract

Copyright of Journal of Pediatric Research is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014
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