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15 results on '"Uwizeye, Cécile"'

2. Multidrug-resistant tuberculosis control in Rwanda overcomes a successful clone that causes most disease over a quarter century

Author

Ngabonziza, Jean Claude S., Rigouts, Leen, Torrea, Gabriela, Decroo, Tom, Kamanzi, Eliane, Lempens, Pauline, Rucogoza, Aniceth, Habimana, Yves M., Laenen, Lies, Niyigena, Belamo E., Uwizeye, Cécile, Ushizimpumu, Bertin, Mulders, Wim, Ivan, Emil, Tzfadia, Oren, Muvunyi, Claude Mambo, Migambi, Patrick, Andre, Emmanuel, Mazarati, Jean Baptiste, Affolabi, Dissou, Umubyeyi, Alaine N., Nsanzimana, Sabin, Portaels, Françoise, Gasana, Michel, de Jong, Bouke C., and Meehan, Conor J.

Published
2022
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7. Rifampicin-Resistant Tuberculosis Control in Rwanda Overcomes a Successful Clone That Causes Most Disease Over a Quarter Century

Author

Ngabonziza, Jean Claude, primary, Rigouts, Leen, additional, Torrea, Gabriela, additional, Decroo, Tom, additional, Kamanzi, Eliane, additional, Lempens, Pauline, additional, Rucogoza, Aniceth, additional, Habimana, Yves M., additional, Laenen, Lies, additional, Niyigena, Belamo E., additional, Uwizeye, Cécile, additional, Ushizimpumu, Bertin, additional, Mulders, Wim, additional, Ivan, Emil, additional, Tzfadia, Oren, additional, Muvunyi, Claude Mambo, additional, Migambi, Patrick, additional, Andre, Emmanuel, additional, Mazarati, Jean Baptiste, additional, Affolabi, Dissou, additional, Umubyeyi, Alaine N., additional, Nsanzimana, Sabin, additional, Portaels, Francoise, additional, Gasana, Michel, additional, de Jong, Bouke C., additional, and Meehan, Conor, additional

Published
2021
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9. Predominant Mycobacterium tuberculosis Families and High Rates of Recent Transmission among New Cases Are Not Associated with Primary Multidrug Resistance in Lima, Peru

Author

Barletta, Francesca, primary, Otero, Larissa, additional, de Jong, Bouke C., additional, Iwamoto, Tomotada, additional, Arikawa, Kentaro, additional, Van der Stuyft, Patrick, additional, Niemann, Stefan, additional, Merker, Matthias, additional, Uwizeye, Cécile, additional, Seas, Carlos, additional, and Rigouts, Leen, additional

Published
2015
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10. Shifts in Mycobacterial Populations and Emerging Drug-Resistance in West and Central Africa

Author

Gehre, Florian, primary, Ejo, Mebrat, additional, Fissette, Kristina, additional, de Rijk, Pim, additional, Uwizeye, Cécile, additional, Nduwamahoro, Elie, additional, Goovaerts, Odin, additional, Affolabi, Dissou, additional, Gninafon, Martin, additional, Lingoupou, Fanny M., additional, Barry, Mamadou Dian, additional, Sow, Oumou, additional, Merle, Corinne, additional, Olliaro, Piero, additional, Ba, Fatoumata, additional, Sarr, Marie, additional, Piubello, Alberto, additional, Noeske, Juergen, additional, Antonio, Martin, additional, Rigouts, Leen, additional, and de Jong, Bouke C, additional

Published
2014
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12. Fine-Needle Aspiration, an Efficient Sampling Technique for Bacteriological Diagnosis of Nonulcerative Buruli Ulcer

Author

Eddyani, Miriam, primary, Fraga, Alexandra G., additional, Schmitt, Fernando, additional, Uwizeye, Cécile, additional, Fissette, Krista, additional, Johnson, Christian, additional, Aguiar, Julia, additional, Sopoh, Ghislain, additional, Barogui, Yves, additional, Meyers, Wayne M., additional, Pedrosa, Jorge, additional, and Portaels, Françoise, additional

Published
2009
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14. Predominant Mycobacterium tuberculosisFamilies and High Rates of Recent Transmission among New Cases Are Not Associated with Primary Multidrug Resistance in Lima, Peru

Author

Barletta, Francesca, Otero, Larissa, de Jong, Bouke C., Iwamoto, Tomotada, Arikawa, Kentaro, Van der Stuyft, Patrick, Niemann, Stefan, Merker, Matthias, Uwizeye, Cécile, Seas, Carlos, and Rigouts, Leen

Abstract

ABSTRACTSputum samples from new tuberculosis (TB) cases were collected over 2 years as part of a prospective study in the northeastern part of Lima, Peru. To measure the contribution of recent transmission to the high rates of multidrug resistance (MDR) in this area, Mycobacterium tuberculosiscomplex (MTBc) isolates were tested for drug susceptibility to first-line drugs and were genotyped by spoligotyping and 15-locus mycobacterial interspersed repetitive-unit (MIRU-15)-variable-number tandem repeat (VNTR) analysis. MDR was found in 6.8% of 844 isolates, of which 593 (70.3%) were identified as belonging to a known MTBc lineage, whereas 198 isolates (23.5%) could not be assigned to these lineages and 12 (1.4%) represented mixed infections. Lineage 4 accounted for 54.9% (n= 463) of the isolates, most of which belonged to the Haarlem family (n= 279). MIRU-15 analysis grouped 551/791 isolates (69.7%) in 102 clusters, with sizes ranging from 2 to 46 strains. The overall high clustering rate suggests a high level of recent transmission in this population, especially among younger patients (odds ratio [OR], 1.6; P= 0.01). Haarlem strains were more prone to cluster, compared to the other families taken together (OR, 2.0; P< 0.0001), while Beijing (OR, 0.6; P= 0.006) and LAM (OR, 0.7; P= 0.07) strains clustered less. Whereas streptomycin-resistant strains were more commonly found in clusters (OR, 1.8; P= 0.03), clustering rates did not differ between MDR and non-MDR strains (OR, 1.8; P= 0.1). Furthermore, only 16/51 MDR strains clustered with other MDR strains, suggesting that patients with primary MDR infections acquired the infections mostly from index cases outside the study population, such as retreated cases.

Published
2015
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