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2,118 results on '"Uriel N"'

1. The carbonyl-lock mechanism underlying non-aromatic fluorescence in biological matter

Author

Gonzalo Díaz Mirón, Jonathan A. Semelak, Luca Grisanti, Alex Rodriguez, Irene Conti, Martina Stella, Jayaramakrishnan Velusamy, Nicola Seriani, Nadja Došlić, Ivan Rivalta, Marco Garavelli, Dario A. Estrin, Gabriele S. Kaminski Schierle, Mariano C. González Lebrero, Ali Hassanali, and Uriel N. Morzan

Subjects
Science
Abstract

Abstract Challenging the basis of our chemical intuition, recent experimental evidence reveals the presence of a new type of intrinsic fluorescence in biomolecules that exists even in the absence of aromatic or electronically conjugated chemical compounds. The origin of this phenomenon has remained elusive so far. In the present study, we identify a mechanism underlying this new type of fluorescence in different biological aggregates. By employing non-adiabatic ab initio molecular dynamics simulations combined with a data-driven approach, we characterize the typical ultrafast non-radiative relaxation pathways active in non-fluorescent peptides. We show that the key vibrational mode for the non-radiative decay towards the ground state is the carbonyl elongation. Non-aromatic fluorescence appears to emerge from blocking this mode with strong local interactions such as hydrogen bonds. While we cannot rule out the existence of alternative non-aromatic fluorescence mechanisms in other systems, we demonstrate that this carbonyl-lock mechanism for trapping the excited state leads to the fluorescence yield increase observed experimentally, and set the stage for design principles to realize novel non-invasive biocompatible probes with applications in bioimaging, sensing, and biophotonics.

Published
2023
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2. Turning up the heat mimics allosteric signaling in imidazole-glycerol phosphate synthase

Author

Federica Maschietto, Uriel N. Morzan, Florentina Tofoleanu, Aria Gheeraert, Apala Chaudhuri, Gregory W. Kyro, Peter Nekrasov, Bernard Brooks, J. Patrick Loria, Ivan Rivalta, and Victor S. Batista

Subjects
Science
Abstract

Abstract Allosteric drugs have the potential to revolutionize biomedicine due to their enhanced selectivity and protection against overdosage. However, we need to better understand allosteric mechanisms in order to fully harness their potential in drug discovery. In this study, molecular dynamics simulations and nuclear magnetic resonance spectroscopy are used to investigate how increases in temperature affect allostery in imidazole glycerol phosphate synthase. Results demonstrate that temperature increase triggers a cascade of local amino acid-to-amino acid dynamics that remarkably resembles the allosteric activation that takes place upon effector binding. The differences in the allosteric response elicited by temperature increase as opposed to effector binding are conditional to the alterations of collective motions induced by either mode of activation. This work provides an atomistic picture of temperature-dependent allostery, which could be harnessed to more precisely control enzyme function.

Published
2023
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3. The collective burst mechanism of angular jumps in liquid water

Author

Adu Offei-Danso, Uriel N. Morzan, Alex Rodriguez, Ali Hassanali, and Asja Jelic

Subjects
Science
Abstract

The collective nature of reorientational dynamics in water remains poorly understood. Here, the authors show that large angular fluctuations require a highly cooperative dynamics involving correlated motion of many water molecules in the hydrogen-bond network that form spatially connected clusters.

Published
2023
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5. Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9

Author

Lukasz Nierzwicki, Kyle W East, Uriel N Morzan, Pablo R Arantes, Victor S Batista, George P Lisi, and Giulia Palermo

Subjects
allostery, molecular dynamics, solution NMR, Medicine, Science, Biology (General), QH301-705.5
Abstract

CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat and associated Cas9 protein) is a molecular tool with transformative genome editing capabilities. At the molecular level, an intricate allosteric signaling is critical for DNA cleavage, but its role in the specificity enhancement of the Cas9 endonuclease is poorly understood. Here, multi-microsecond molecular dynamics is combined with solution NMR and graph theory-derived models to probe the allosteric role of key specificity-enhancing mutations. We show that mutations responsible for increasing the specificity of Cas9 alter the allosteric structure of the catalytic HNH domain, impacting the signal transmission from the DNA recognition region to the catalytic sites for cleavage. Specifically, the K855A mutation strongly disrupts the allosteric connectivity of the HNH domain, exerting the highest perturbation on the signaling transfer, while K810A and K848A result in more moderate effects on the allosteric communication. This differential perturbation of the allosteric signal correlates to the order of specificity enhancement (K855A > K848A ~ K810A) observed in biochemical studies, with the mutation achieving the highest specificity most strongly perturbing the signaling transfer. These findings suggest that alterations of the allosteric communication from DNA recognition to cleavage are critical to increasing the specificity of Cas9 and that allosteric hotspots can be targeted through mutational studies for improving the system’s function.

Published
2021
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6. Aqueous Solution Chemistry In Silico and the Role of Data Driven Approaches

Author

Banerjee, Debarshi, Azizi, Khatereh, Egan, Colin K., Donkor, Edward Danquah, Malosso, Cesare, Di Pino, Solana, Miron, Gonzalo Diaz, Stella, Martina, Sormani, Giulia, Hozana, Germaine Neza, Monti, Marta, Morzan, Uriel N., Rodriguez, Alex, Cassone, Giuseppe, Jelic, Asja, Scherlis, Damian, and Hassanali, Ali

Subjects
Physics - Chemical Physics
Abstract

The use of computer simulations to study the properties of aqueous systems is, today more than ever, an active area of research. In this context, during the last decade there has been a tremendous growth in the use of data-driven approaches to develop more accurate potentials for water as well as to characterize its complexity in chemical and biological contexts. We highlight the progress, giving a historical context, on the path to the development of many-body and reactive potentials to model aqueous chemistry, including the role of machine learning strategies. We focus specifically on conceptual and methodological challenges along the way in performing simulations that seek to tackle problems in modeling the chemistry of aqueous solutions. In conclusion, we summarize our perspectives on the use and integration of advanced data-science techniques to provide chemical insights in physical chemistry and how this will influence computer simulations of aqueous systems in the future., Comment: 37 Pages. 7 Figures. Submitted to Chemical Physics Reviews

Published
2024
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7. Recovery of the maternal skeleton after lactation is impaired by advanced maternal age but not by reduced IGF availability in the mouse.

Author

Monika D Rogowska, Uriel N V Pena, Nimrat Binning, and Julian K Christians

Subjects
Medicine, Science
Abstract

BackgroundLactation results in substantial maternal bone loss that is recovered following weaning. However, the mechanisms underlying this recovery, and in particular the role of insulin-like growth factor 1 (IGF-I), is not clear. Furthermore, there is little data regarding whether recovery is affected by advanced maternal age.MethodsUsing micro-computed tomography, we studied bone recovery following lactation in mice at 2, 5 and 7 months of age. We also investigated the effects of reduced IGF-I availability using mice lacking PAPP-A2, a protease of insulin-like growth factor binding protein 5 (IGFBP-5).ResultsIn 2 month old mice, lactation affected femoral trabecular and cortical bone, but only cortical bone showed recovery 3 weeks after weaning. This recovery was not affected by deletion of the Pappa2 gene. The amount of trabecular bone was reduced in 5 and 7 month old mice, and was not further reduced by lactation. However, the recovery of cortical bone was impaired at 5 and 7 months compared with at 2 months.ConclusionsRecovery of the maternal skeleton after lactation is impaired in moderately-aged mice compared with younger mice. Our results may be relevant to the long-term effects of breastfeeding on the maternal skeleton in humans, particularly given the increasing median maternal age at childbearing.

Published
2021
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8. Exploring the Mechanisms Behind Non Aromatic Fluorescence with Density Functional Tight Binding Method

Author

Mirón, Gonzalo Díaz, Lien-Medrano, Carlos R., Banerjee, Debarshi, Morzan, Uriel N., Sentef, Michael A., Gebauer, Ralph, and Hassanali, Ali

Subjects
Physics - Chemical Physics
Abstract

Recent experimental findings reveal non-conventional fluorescence emission in biological systems devoid of conjugated bonds or aromatic compounds, termed \textit{Non-Aromatic Fluorescence} (NAF). This phenomenon is exclusive to aggregated or solid states, remaining absent in monomeric solutions. Previous studies focused on small model systems in vacuum show that the carbonyl stretching mode along with strong interaction of short hydrogen bonds (SHBs) remain the primary vibrational mode explaining NAF in these systems. In order to simulate larger model systems taking into account the effects of the surrounding environment, in this work we propose using the density functional tight-binding (DFTB) method in combination with non-adiabatic molecular dynamics (NAMD) and the mixed quantum/molecular mechanics (QM/MM) approach. We investigate the mechanism behind NAF in the crystal structure of L-pyroglutamine-ammonium, comparing it with the related non-fluorescent amino acid L-glutamine. Our results extend our previous findings to more realistic systems, demonstrating the efficiency and robustness of the proposed DFTB method in the context of NAMD in biological systems. Furthemore, due to its inherent low computational cost, this method allows for a better sampling on the non-radiative events at the conical intersection which is crucial for a complete understanding of this phenomenon. Beyond contributing to the ongoing exploration of NAF, this work paves the way for future application of this method in more complex biological systems such as amyloid aggregates, biomaterials and non-aromatic proteins.

Published
2024

9. Chemical Reactivity and Spectroscopy Explored From QM/MM Molecular Dynamics Simulations Using the LIO Code

Author

Juan P. Marcolongo, Ari Zeida, Jonathan A. Semelak, Nicolás O. Foglia, Uriel N. Morzan, Dario A. Estrin, Mariano C. González Lebrero, and Damián A. Scherlis

Subjects
QM/MM, DFT, GPU, free energy, TDDFT, Chemistry, QD1-999
Abstract

In this work we present the current advances in the development and the applications of LIO, a lab-made code designed for density functional theory calculations in graphical processing units (GPU), that can be coupled with different classical molecular dynamics engines. This code has been thoroughly optimized to perform efficient molecular dynamics simulations at the QM/MM DFT level, allowing for an exhaustive sampling of the configurational space. Selected examples are presented for the description of chemical reactivity in terms of free energy profiles, and also for the computation of optical properties, such as vibrational and electronic spectra in solvent and protein environments.

Published
2018
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10. Water Network Dynamics Next to the Oxygen-Evolving Complex of Photosystem II

Author

Krystle Reiss, Uriel N. Morzan, Alex T. Grigas, and Victor S. Batista

Subjects
oxygen-evolving complex, community network analysis, water channels, Inorganic chemistry, QD146-197
Abstract

The influence of the environment on the functionality of the oxygen-evolving complex (OEC) of photosystem II has long been a subject of great interest. In particular, various water channels, which could serve as pathways for substrate water diffusion, or proton translocation, are thought to be critical to catalytic performance of the OEC. Here, we address the dynamical nature of hydrogen bonding along the water channels by performing molecular dynamics (MD) simulations of the OEC and its surrounding protein environment in the S1 and S2 states. Through the eigenvector centrality (EC) analysis, we are able to determine the characteristics of the water network and assign potential functions to the major channels, namely that the narrow and broad channels are likely candidates for proton/water transport, while the large channel may serve as a path for larger ions such as chloride and manganese thought to be essential during PSII assembly.

Published
2019
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11. Priority Questions and Horizon Scanning for Conservation: A Comparative Study.

Author

Salit Kark, William J Sutherland, Uri Shanas, Keren Klass, Hila Achisar, Tamar Dayan, Yael Gavrieli, Ronit Justo-Hanani, Yael Mandelik, Nir Orion, David Pargament, Michelle Portman, Orna Reisman-Berman, Uriel N Safriel, Gad Schaffer, Noa Steiner, Israel Tauber, and Noam Levin

Subjects
Medicine, Science
Abstract

Several projects aimed at identifying priority issues for conservation with high relevance to policy have recently been completed in several countries. Two major types of projects have been undertaken, aimed at identifying (i) policy-relevant questions most imperative to conservation and (ii) horizon scanning topics, defined as emerging issues that are expected to have substantial implications for biodiversity conservation and policy in the future. Here, we provide the first overview of the outcomes of biodiversity and conservation-oriented projects recently completed around the world using this framework. We also include the results of the first questions and horizon scanning project completed for a Mediterranean country. Overall, the outcomes of the different projects undertaken (at the global scale, in the UK, US, Canada, Switzerland and in Israel) were strongly correlated in terms of the proportion of questions and/or horizon scanning topics selected when comparing different topic areas. However, some major differences were found across regions. There was large variation among regions in the percentage of proactive (i.e. action and response oriented) versus descriptive (non-response oriented) priority questions and in the emphasis given to socio-political issues. Substantial differences were also found when comparing outcomes of priority questions versus horizon scanning projects undertaken for the same region. For example, issues related to climate change, human demography and marine ecosystems received higher priority as horizon scanning topics, while ecosystem services were more emphasized as current priority questions. We suggest that future initiatives aimed at identifying priority conservation questions and horizon scanning topics should allow simultaneous identification of both current and future priority issues, as presented here for the first time. We propose that further emphasis on social-political issues should be explicitly integrated into future related projects.

Published
2016
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12. The Collective Burst Mechanism of Angular Jumps in Liquid Water

Author

Offei-Danso, Adu, Morzan, Uriel N., Rodriguez, Alex, Hassanali, Ali, and Jelic, Asja

Subjects
Condensed Matter - Soft Condensed Matter, Physics - Chemical Physics
Abstract

Understanding the microscopic origins of collective reorientational motions in aqueous systems requires techniques that allow us to reach beyond our chemical imagination. Herein, we elucidate a mechanism using unsupervised learning, showing that large angular jumps in liquid water involve highly cooperative orchestrated motions. Our automatized detection of angular fluctuations, unravels a heterogeneity in the type of angular jumps occurring concertedly in the system. We show that large orientational motions require a highly collective dynamic process involving correlated motion of up to 10% of water molecules in the hydrogen-bond network that form spatially connected clusters. This phenomenon is rooted in the collective fluctuations of the network topology which results in the creation of defects in waves on the ThZ timescale. The mechanism we propose involves a cascade of hydrogen-bond fluctuations underlying angular jumps and provides new insights into the current localized picture of angular jumps, and in its wide use in the interpretations of numerous spectroscopies as well in reorientational dynamics of water near biological and inorganic systems., Comment: 12 pages, 7 figures, Supplementary Information as ancillary file

Published
2022
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17. Water Self-Dissociation is Insensitive to Nanoscale Environments

Author

Di Pino, Solana, Sirkin, Yamila A. Perez, Morzan, Uriel N., Sánchez, Verónica M., Hassanali, Ali, and Scherlis, Damian A.

Subjects
Condensed Matter - Soft Condensed Matter
Abstract

Nanoconfinement effects on water dissociation and reactivity remain controversial, despite their importance to understand the aqueous chemistry at interfaces, pores, or aerosols. The pKw in confined environments has been assessed from experiments and simulations in a few specific cases, leading to dissimilar conclusions. Here, with the use of carefully designed \textit{ab-initio} simulations, we demonstrate that the energetics of bulk water dissociation is conserved intact to unexpectedly small length-scales, down to aggregates of only a dozen molecules or pores of widths below 2 nm. The reason is that most of the free-energy involved in water autoionization comes from breaking the O-H covalent bond, which has a comparable barrier in the bulk liquid, in a small droplet of nanometer size, or in a nanopore in the absence of strong interfacial interactions. Thus, dissociation free-energy profiles in nanoscopic aggregates or in 2D slabs of 1 nm width reproduce the behavior corresponding to the bulk liquid, regardless of whether the corresponding nanophase is delimited by a solid or a gas interface. The present work provides a definite and fundamental description of the mechanism and thermodynamics of water dissociation at different scales with broader implications on reactivity and self-ionization at the air-liquid interface.

Published
2021

18. Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9

Author

Nierzwicki, Lukasz, East, Kyle W, Morzan, Uriel N, Arantes, Pablo R, Batista, Victor S, Lisi, George P, and Palermo, Giulia

Subjects
Genetics, Allosteric Regulation, CRISPR-Cas Systems, Genetic Variation, Genotype, Molecular Dynamics Simulation, Molecular Structure, Mutation, Streptococcus pyogenes, allostery, molecular dynamics, solution NMRS, pyogenes, S. pyogenes, molecular biophysics, solution NMR, structural biology, Biochemistry and Cell Biology
Abstract

CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat and associated Cas9 protein) is a molecular tool with transformative genome editing capabilities. At the molecular level, an intricate allosteric signaling is critical for DNA cleavage, but its role in the specificity enhancement of the Cas9 endonuclease is poorly understood. Here, multi-microsecond molecular dynamics is combined with solution NMR and graph theory-derived models to probe the allosteric role of key specificity-enhancing mutations. We show that mutations responsible for increasing the specificity of Cas9 alter the allosteric structure of the catalytic HNH domain, impacting the signal transmission from the DNA recognition region to the catalytic sites for cleavage. Specifically, the K855A mutation strongly disrupts the allosteric connectivity of the HNH domain, exerting the highest perturbation on the signaling transfer, while K810A and K848A result in more moderate effects on the allosteric communication. This differential perturbation of the allosteric signal correlates to the order of specificity enhancement (K855A > K848A ~ K810A) observed in biochemical studies, with the mutation achieving the highest specificity most strongly perturbing the signaling transfer. These findings suggest that alterations of the allosteric communication from DNA recognition to cleavage are critical to increasing the specificity of Cas9 and that allosteric hotspots can be targeted through mutational studies for improving the system's function.

Published
2021

19. Allosteric Motions of the CRISPR–Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics

Author

East, Kyle W, Newton, Jocelyn C, Morzan, Uriel N, Narkhede, Yogesh B, Acharya, Atanu, Skeens, Erin, Jogl, Gerwald, Batista, Victor S, Palermo, Giulia, and Lisi, George P

Subjects
Genetics, Human Genome, 1.1 Normal biological development and functioning, Underpinning research, Allosteric Regulation, CRISPR-Cas Systems, Deoxyribonucleases, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Chemical Sciences, General Chemistry
Abstract

CRISPR-Cas9 is a widely employed genome-editing tool with functionality reliant on the ability of the Cas9 endonuclease to introduce site-specific breaks in double-stranded DNA. In this system, an intriguing allosteric communication has been suggested to control its DNA cleavage activity through flexibility of the catalytic HNH domain. Here, solution NMR experiments and a novel Gaussian-accelerated molecular dynamics (GaMD) simulation method are used to capture the structural and dynamic determinants of allosteric signaling within the HNH domain. We reveal the existence of a millisecond time scale dynamic pathway that spans HNH from the region interfacing the adjacent RuvC nuclease and propagates up to the DNA recognition lobe in full-length CRISPR-Cas9. These findings reveal a potential route of signal transduction within the CRISPR-Cas9 HNH nuclease, advancing our understanding of the allosteric pathway of activation. Further, considering the role of allosteric signaling in the specificity of CRISPR-Cas9, this work poses the mechanistic basis for novel engineering efforts aimed at improving its genome-editing capability.

Published
2020

20. Short hydrogen bonds enhance nonaromatic protein-related fluorescence

Author

Stephens, Amberley D., Qaisrani, Muhammad Nawaz, Ruggiero, Michael T., Mirón, Gonzalo Díaz, Morzan, Uriel N., Lebrero, Mariano C. González, Jones, Saul T. E., Poli, Emiliano, Bond, Andrew D., Woodhams, Philippa J., Kleist, Elyse M., Grisanti, Luca, Gebauer, Ralph, Zeitler, J. Axel, Credgington, Dan, Hassanali, Ali, and Schierle, Gabriele S. Kaminski

Published
2021

21. Eigenvector Centrality Distribution for Characterization of Protein Allosteric Pathways

Author

Negre, Christian F. A., Morzan, Uriel N., Hendrickson, Heidi, Pal, Rhitankar, Lisi, George P., Loria, J. Patrick, Rivalta, Ivan, Ho, Junming, and Batista, Victor S.

Subjects
Quantitative Biology - Biomolecules, Condensed Matter - Soft Condensed Matter
Abstract

Determining the principal energy pathways for allosteric communication in biomolecules, that occur as a result of thermal motion, remains challenging due to the intrinsic complexity of the systems involved. Graph theory provides an approach for making sense of such complexity, where allosteric proteins can be represented as networks of amino acids. In this work, we establish the eigenvector centrality metric in terms of the mutual information, as a mean of elucidating the allosteric mechanism that regulates the enzymatic activity of proteins. Moreover, we propose a strategy to characterize the range of the physical interactions that underlie the allosteric process. In particular, the well known enzyme, imidazol glycerol phosphate synthase (IGPS), is utilized to test the proposed methodology. The eigenvector centrality measurement successfully describes the allosteric pathways of IGPS, and allows to pinpoint key amino acids in terms of their relevance in the momentum transfer process. The resulting insight can be utilized for refining the control of IGPS activity, widening the scope for its engineering. Furthermore, we propose a new centrality metric quantifying the relevance of the surroundings of each residue. In addition, the proposed technique is validated against experimental solution NMR measurements yielding fully consistent results. Overall, the methodologies proposed in the present work constitute a powerful and cost effective strategy to gain insight on the allosteric mechanism of proteins.

Published
2017
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22. Empagliflozin in the treatment of heart failure with reduced ejection fraction in addition to background therapies and therapeutic combinations (EMPEROR-Reduced): a post-hoc analysis of a randomised, double-blind trial

Author

Packer, M, Anker, S, Butler, J, Filippatos, G, Pocock, S, Zannad, F, Ferreira, JP, Brueckmann, M, George, J, Jamal, W, Welty, FK, Palmer, M, Clayton, T, Parhofer, KG, Pedersen, TR, Greenberg, B, Konstam, MA, Lees, KR, Carson, P, Doehner, W, Miller, A, Haas, M, Pehrson, S, Komajda, M, Anand, I, Teerlink, J, Rabinstein, A, Steiner, T, Kamel, H, Tsivgoulis, G, Lewis, J, Freston, J, Kaplowitz, N, Mann, J, Petrie, J, Perrone, S, Nicholls, S, Janssens, S, Bocchi, E, Giannetti, N, Verma, S, Zhang, J, Spinar, J, Seronde, M-F, Boehm, M, Merkely, B, Chopra, V, Senni, M, Taddi, S, Tsutsui, H, Choi, D-J, Chuquiure, E, La Rocca, HPB, Ponikowski, P, Juanatey, JRG, Squire, I, Januzzi, J, Pina, I, Bernstein, R, Cheung, A, Green, J, Kaul, S, Lam, C, Lip, G, Marx, N, McCullough, P, Mehta, C, Rosenstock, J, Sattar, N, Scirica, B, Shah, S, Wanner, C, Aizenberg, D, Cartasegna, L, Colombo Berra, F, Colombo, H, Fernandez Moutin, M, Glenny, J, Alvarez Lorio, C, Anauch, D, Campos, R, Facta, A, Fernandez, A, Ahuad Guerrero, R, Lobo Márquez, L, Leon de la Fuente, RA, Mansilla, M, Hominal, M, Hasbani, E, Najenson, M, Moises Azize, G, Luquez, H, Guzman, L, Sessa, H, Amuchástegui, M, Salomone, O, Perna, E, Piskorz, D, Sicer, M, Perez de Arenaza, D, Zaidman, C, Nani, S, Poy, C, Resk, J, Villarreal, R, Majul, C, Smith Casabella, T, Sassone, S, Liberman, A, Carnero, G, Caccavo, A, Berli, M, Budassi, N, Bono, J, Alvarisqueta, A, Amerena, J, Kostner, K, Hamilton, A, Begg, A, Beltrame, J, Colquhoun, D, Gordon, G, Sverdlov, A, Vaddadi, G, Wong, J, Coller, J, Prior, D, Friart, A, Leone, A, Vervoort, G, Timmermans, P, Troisfontaines, P, Franssen, C, Sarens, T, Vandekerckhove, H, Van De Borne, P, Chenot, F, De Sutter, J, De Vuyst, E, Debonnaire, P, Dupont, M, Pereira Dutra, O, Canani, LH, Vieira Moreira, MdC, de Souza, W, Backes, LM, Maia, L, De Souza Paolino, B, Manenti, ER, Saporito, W, Villaça Guimarães Filho, F, Franco Hirakawa, T, Saliba, LA, Neuenschwander, FC, de Freitas Zerbini, CA, Gonçalves, G, Gonçalves Mello, Y, Ascenção de Souza, J, Beck da Silva Neto, L, Bocchi, EA, Da Silveira, J, de Moura Xavier Moraes Junior, JB, de Souza Neto, JD, Hernandes, M, Finimundi, HC, Sampaio, CR, Vasconcellos, E, Neves Mancuso, FJ, Noya Rabelo, MM, Rodrigues Bacci, M, Santos, F, Vidotti, M, Simões, MV, Gomes, FL, Vieira Nascimento, C, Precoma, D, Helfenstein Fonseca, FA, Ribas Fortes, JA, Leães, PE, Campos de Albuquerque, D, Kerr Saraiva, JF, Rassi, S, Alves da Costa, FA, Reis, G, Zieroth, S, Dion, D, Savard, D, Bourgeois, R, Constance, C, Anderson, K, Leblanc, M-H, Yung, D, Swiggum, E, Pliamm, L, Pesant, Y, Tyrrell, B, Huynh, T, Spiegelman, J, Lavoie, J-P, Hartleib, M, Bhargava, R, Straatman, L, Virani, S, Costa-Vitali, A, Hill, L, Heffernan, M, Khaykin, Y, Ricci, J, Senaratne, M, Zhai, A, Lubelsky, B, Toma, M, Yao, L, McKelvie, R, Noronha, L, Babapulle, M, Pandey, A, Curnew, G, Lavoie, A, Berlingieri, J, Kouz, S, Lonn, E, Chehayeb, R, Zheng, Y, Sun, Y, Cui, H, Fan, Z, Han, X, Jiang, X, Tang, Q, Zhou, J, Zheng, Z, Zhang, X, Zhang, N, Zhang, Y, Shen, A, Yu, J, Ye, J, Yao, Y, Yan, J, Xu, X, Wang, Z, Ma, J, Li, Y, Li, S, Lu, S, Kong, X, Song, Y, Yang, G, Yao, Z, Pan, Y, Guo, X, Sun, Z, Dong, Y, Zhu, J, Peng, D, Yuan, Z, Lin, J, Yin, Y, Jerabek, O, Burianova, H, Fiala, T, Hubac, J, Ludka, O, Monhart, Z, Vodnansky, P, Zeman, K, Foldyna, D, Krupicka, J, Podpera, I, Busak, L, Radvan, M, Vomacka, Z, Prosecky, R, Cifkova, R, Durdil, V, Vesely, J, Vaclavik, J, Cervinka, P, Linhart, A, Brabec, T, Miklik, R, Bourhaial, H, Olbrich, H-G, Genth-Zotz, S, Kemala, E, Lemke, B, Böhm, M, Schellong, S, Rieker, W, Heitzer, T, Ince, H, Faghih, M, Birkenfeld, A, Begemann, A, Ghanem, A, Ujeyl, A, von Haehling, S, Dorsel, T, Bauersachs, J, Prull, M, Weidemann, F, Darius, H, Nickenig, G, Wilke, A, Sauter, J, Rauch-Kroehnert, U, Frey, N, Schulze, CP, König, W, Maier, L, Menzel, F, Proskynitopoulos, N, Ebert, H-H, Sarnighausen, H-E, Düngen, H-D, Licka, M, Stellbrink, C, Winkelmann, B, Menck, N, López-Sendón, JL, de la Fuente Galán, L, Delgado Jiménez, JF, Manito Lorite, N, Pérez de Juan Romero, M, Galve Basilio, E, Cereto Castro, F, González Juanatey, JR, Gómez, JJ, Sanmartín Fernández, M, Garcia-Moll Marimon, X, Pascual Figal, D, Bover Freire, R, Bonnefoy Cudraz, E, Jobbe Duval, A, Tomasevic, D, Habib, G, Isnard, R, Picard, F, Khanoyan, P, Dubois-Rande, J-L, Galinier, M, Roubille, F, Alexandre, J, Babuty, D, Delarche, N, Berneau, J-B, Girerd, N, Saxena, M, Rosano, G, Yousef, Z, Clifford, C, Arden, C, Bakhai, A, Boos, C, Jenkins, G, Travill, C, Price, D, Koenyves, L, Lakatos, F, Matoltsy, A, Noori, E, Zilahi, Z, Andrassy, P, Kancz, S, Simon, G, Sydo, T, Vorobcsuk, A, Kiss, RG, Toth, K, Szakal, I, Nagy, L, Barany, T, Nagy, A, Szolnoki, E, Chopra, VK, Mandal, S, Rastogi, V, Shah, B, Mullasari, A, Shankar, J, Mehta, V, Oomman, A, Kaul, U, Komarlu, S, Kahali, D, Bhagwat, A, Vijan, V, Ghaisas, NK, Mehta, A, Kashyap, J, Kothari, Y, TaddeI, S, Scherillo, M, Zacà, V, Genovese, S, Salvioni, A, Fucili, A, Fedele, F, Cosmi, F, Volpe, M, Mazzone, C, Esposito, G, Doi, M, Yamamoto, H, Sakagami, S, Oishi, S, Yasaka, Y, Tsuboi, H, Fujino, Y, Matsuoka, S, Watanabe, Y, Himi, T, Ide, T, Ichikawa, M, Kijima, Y, Koga, T, Yuda, S, Fukui, K, Kubota, T, Manita, M, Fujinaga, H, Matsumura, T, Fukumoto, Y, Kato, R, Kawai, Y, Hiasa, G, Kazatani, Y, Mori, M, Ogimoto, A, Inoko, M, Oguri, M, Kinoshita, M, Okuhara, K, Watanabe, N, Ono, Y, Otomo, K, Sato, Y, Matsunaga, T, Takaishi, A, Miyagi, N, Uehara, H, Takaishi, H, Urata, H, Kataoka, T, Matsubara, H, Matsumoto, T, Suzuki, T, Takahashi, N, Imamaki, M, Yoshitama, T, Saito, T, Sekino, H, Furutani, Y, Koda, M, Shinozaki, T, Hirabayashi, K, Tsunoda, R, Yonezawa, K, Hori, H, Yagi, M, Arikawa, M, Hashizume, T, Ishiki, R, Koizumi, T, Nakayama, K, Taguchi, S, Nanasato, M, Yoshida, Y, Tsujiyama, S, Nakamura, T, Oku, K, Shimizu, M, Suwa, M, Momiyama, Y, Sugiyama, H, Kobayashi, K, Inoue, S, Kadokami, T, Maeno, K, Kawamitsu, K, Maruyama, Y, Nakata, A, Shibata, T, Wada, A, Cho, H-J, Na, JO, Yoo, B-S, Choi, J-O, Hong, SK, Shin, J-H, Cho, M-C, Han, SH, Jeong, J-O, Kim, J-J, Kang, SM, Kim, D-S, Kim, MH, Llamas Esperon, G, Illescas Díaz, J, Fajardo Campos, P, Almeida Alvarado, J, Bazzoni Ruiz, A, Echeverri Rico, J, Lopez Alcocer, I, Valle Molina, L, Hernandez Herrera, C, Calvo Vargas, C, Padilla Padilla, FG, Rodriguez Briones, I, Chuquiure Valenzuela, EJJR, Aguilera Real, ME, Carrillo Calvillo, J, Alpizar Salazar, M, Cervantes Escárcega, JL, Velasco Sanchez, R, Al - Windy, N, van Heerebeek, L, Bellersen, L, Brunner-La Rocca, H-P, Post, J, Linssen, GCM, van de Wetering, M, Peters, R, van Stralen, R, Groutars, R, Smits, P, Yilmaz, A, Kok, WEM, Van der Meer, P, Dijkmans, P, Troquay, R, van Alem, AP, Van de Wal, R, Handoko, L, Westendorp, ICD, van Bergen, PFMM, Rensing, BJWM, Hoogslag, P, Kietselaer, B, Kragten, JA, den Hartog, FR, Alings, A, Danilowicz-Szymanowicz, L, Raczak, G, Piesiewicz, W, Zmuda, W, Kus, W, Podolec, P, Musial, W, Drelich, G, Kania, G, Miekus, P, Mazur, S, Janik, A, Spyra, J, Peruga, J, Balsam, P, Krakowiak, B, Szachniewicz, J, Ginel, M, Grzybowski, J, Chrustowski, W, Wojewoda, P, Kalinka, A, Zurakowski, A, Koc, R, Debinski, M, Fil, W, Kujawiak, M, Forys, J, Kasprzak, M, Krol, M, Michalski, P, Mirek-Bryniarska, E, Radwan, K, Skonieczny, G, Stania, K, Skoczylas, G, Madej, A, Jurowiecki, J, Firek, B, Wozakowska-Kaplon, B, Cymerman, K, Neutel, J, Adams, K, Balfour, P, Deswal, A, Djamson, A, Duncan, P, Hong, M, Murray, C, Rinde-Hoffman, D, Woodhouse, S, MacNevin, R, Rama, B, Broome-Webster, C, Kindsvater, S, Abramov, D, Barettella, M, Pinney, S, Herre, J, Cohen, A, Vora, K, Challappa, K, West, S, Baum, S, Cox, J, Jani, S, Karim, A, Akhtar, A, Quintana, O, Paukman, L, Goldberg, R, Bhatti, Z, Budoff, M, Bush, E, Potler, A, Delgado, R, Ellis, B, Dy, J, Fialkow, J, Sangrigoli, R, Ferdinand, K, East, C, Falkowski, S, Donahoe, S, Ebrahimi, R, Kline, G, Harris, B, Khouzam, R, Jaffrani, N, Jarmukli, N, Kazemi, N, Koren, M, Friedman, K, Herzog, W, Silva Enciso, J, Cheung, D, Grover-McKay, M, Hauptman, P, Mikhalkova, D, Hegde, V, Hodsden, J, Khouri, S, McGrew, F, Littlefield, R, Bradley, P, McLaurin, B, Lupovitch, S, Labin, I, Rao, V, Leithe, M, Lesko, M, Lewis, N, Lombardo, D, Mahal, S, Malhotra, V, Dauber, I, Banerjee, A, Needell, J, Miller, G, Paladino, L, Munuswamy, K, Nanna, M, McMillan, E, Mumma, M, Napoli, M, Nelson, W, O'Brien, T, Adlakha, A, Onwuanyi, A, Serota, H, Schmedtje, J, Paraschos, A, Potu, R, Sai-Sudhakar, C, Saltzberg, M, Sauer, A, Shah, P, Skopicki, H, Bui, H, Carr, K, Stevens, G, Tahirkheli, N, Tallaj, J, Yousuf, K, Trichon, B, Welker, J, Tolerico, P, Vest, A, Vivo, R, Wang, X, Abadier, R, Dunlap, S, Weintraub, N, Malik, A, Kotha, P, Zaha, V, Kim, G, Uriel, N, Greene, T, Salacata, A, Arora, R, Gazmuri, R, Kobayashi, J, Iteld, B, Vijayakrishnan, R, Dab, R, Mirza, Z, Marques, V, Nallasivan, M, Bensimhon, D, Peart, B, Saint-Jacques, H, Barringhaus, K, Contreras, J, Gupta, A, Koneru, S, Nguyen, V, Verma, Subodh, Dhingra, Nitish K, Butler, Javed, Anker, Stefan D, Ferreira, Joao Pedro, Filippatos, Gerasimos, Januzzi, James L, Lam, Carolyn S P, Sattar, Naveed, Peil, Barbara, Nordaby, Matias, Brueckmann, Martina, Pocock, Stuart J, Zannad, Faiez, and Packer, Milton

Published
2022
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23. Correlation Between the Subtype of Anti-HLA Donor Specific Antibodies and Rejection Assessed by Molecular Microscope

Author

Fernandez Valledor, A., primary, Moeller, C.M., additional, Baranowska, J., additional, Lee, C., additional, Rubinstein, G., additional, Rahman, S., additional, Mehlman, Y., additional, Rahman, A., additional, Lotan, D., additional, Oren, D., additional, DeFilippis, E., additional, Bae, D., additional, Oh, K., additional, Majure, D., additional, Theodoropoulos, K., additional, Lin, E., additional, Topkara, V., additional, Colombo, P., additional, Yuzefpolskaya, M., additional, Fried, J., additional, Raikhelkar, J., additional, Clerkin, K., additional, Latif, F., additional, Sayer, G., additional, and Uriel, N., additional

Published
2024
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24. Outcomes Comparison of Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock with Acute Decompensated Heart Failure versus Acute Myocardial Infarction

Author

Almodovar-Cruz, G.E., primary, Zhao, Y., additional, Vinogradsky, A., additional, Powley, T., additional, Lin, A., additional, Kaku, Y., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Sayer, G., additional, Uriel, N., additional, Fried, J., additional, and Takeda, K., additional

Published
2024
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25. History of Malignancy and Rejection Outcomes Assessed by Molecular Microscope (MMDx)

Author

Rubinstein, G., primary, Fernandez Valledor, A., additional, Moeller, C.M., additional, Slomovich, S., additional, Oren, D., additional, Baranowska, J., additional, Rahman, S., additional, Lee, C., additional, Oh, K., additional, Bae, D., additional, Topkara, V., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Lotan, D., additional, DeFilippis, E.M., additional, Theodoropoulos, K., additional, Fried, J., additional, Lin, E., additional, Majure, D., additional, Clerkin, K., additional, Latif, F., additional, Sayer, G., additional, Uriel, N., additional, and Raikhelkar, J., additional

Published
2024
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26. Consistent Sublingual Microvascular Health Among Heart Transplant Recipients Regardless of Coronary Allograft Vasculopathy Status

Author

Moeller, C.M., primary, Valledor, A. Fernandez, additional, Oren, D., additional, Lee, C., additional, Rahman, S., additional, Baranowska, J., additional, Rubinstein, G., additional, Lotan, D., additional, DeFilippis, E.M., additional, Raikhelkar, J.K., additional, Clerkin, K.J., additional, Fried, J.A., additional, Latif, F., additional, Uriel, N., additional, and Sayer, G.T., additional

Published
2024
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27. Heart Transplantation in a Patient with Active Thyroid Cancer

Author

Mehlman, Y., primary, Yuzefpolskaya, M., additional, Fried, J., additional, Clerkin, K., additional, Bae, D., additional, DeFilippis, E., additional, Oh, K., additional, Theodoropoulos, K., additional, Lee, S., additional, Colombo, P., additional, Lin, E., additional, Latif, F., additional, Sayer, G., additional, Uriel, N., additional, and Raikhelkar, J., additional

Published
2024
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28. Sublingual Microcirculation in Acute Mechanical Circulatory Support in Cardiogenic Shock

Author

Rahman, S., primary, Lee, C., additional, Baranowska, J., additional, Moeller, C., additional, Fernandez Valledor, A., additional, Rubinstein, G., additional, Oren, D., additional, Miller, T., additional, Lotan, D., additional, Rahman, A., additional, Kaku, Y., additional, Raikhelkar, J., additional, Takeda, K., additional, DeFilippis, E., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Majure, D., additional, Clerkin, K., additional, Burkhoff, D., additional, Sayer, G., additional, Uriel, N., additional, and Fried, J., additional

Published
2024
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31. Implications of ABO Unmatched Donors on Cardiac Allograft Rejection Assessed by the Molecular Microscope (MMDx)

Author

Moeller, C.M., primary, Valledor, A. Fernandez, additional, Oren, D., additional, Baranowska, J., additional, Rubinstein, G., additional, Lee, C., additional, Rahman, S., additional, Oh, K., additional, Bae, D., additional, Lotan, D., additional, DeFilippis, E.M., additional, Fried, J., additional, Theodoropoulos, K., additional, Clerkin, K., additional, Latif, F., additional, Raikhelkar, J., additional, Uriel, N., additional, and Sayer, G.T., additional

Published
2024
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32. Molecular Microscope Findings in Low-Grade Histological Rejection: A Less Benign Reality Than Assumed

Author

Rubinstein, G., primary, Fernandez Valledor, A., additional, Moeller, C.M., additional, Slomovich, S., additional, Oren, D., additional, Baranowska, J., additional, Rahman, S., additional, Lee, C., additional, Oh, K., additional, Bae, D., additional, Raikhelkar, J., additional, Topkara, V., additional, Lotan, D., additional, DeFilippis, E.M., additional, Theodoropoulos, K., additional, Fried, J., additional, Lin, E., additional, Majure, D., additional, Clerkin, K., additional, Colombo, P., additional, Yuzefpolskaya, M., additional, Latif, F., additional, Sayer, G., additional, and Uriel, N., additional

Published
2024
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33. Racial and Ethnic Disparities in De-Novo Donor Specific Antibodies (DSA) and Rejection Rates in Heart Transplant Recipients Assessed by Molecular Microscope

Author

Oren, D., primary, Moeller, C.M., additional, Fernandez Valledor, A., additional, Rubinstein, G., additional, Baranowska, J., additional, Rahman, S., additional, Lee, C., additional, Oh, K., additional, Bae, D., additional, Raikhelkar, J.K., additional, Topkara, V., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Lotan, D., additional, DeFilippis, E.M., additional, Theodoropoulos, K., additional, Fried, J., additional, Lin, E., additional, Majure, D., additional, Clerkin, K., additional, Latif, F., additional, Sayer, G., additional, and Uriel, N., additional

Published
2024
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34. Sex Differences in Allograft Rejection After Heart Transplantation (HT). Molecular Microscope (MMDx) Results

Author

Moeller, C., primary, Fernandez Valledor, A., additional, Rahman, S., additional, Oren, D., additional, Lotan, D., additional, Rubinstein, G., additional, Mehlman, Y., additional, Raikhelkar, J., additional, Yuzefpolskaya, M., additional, DeFilippis, E.M., additional, Fried, J., additional, Clerkin, K., additional, Uriel, N., additional, and Sayer, G.T., additional

Published
2024
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35. Microcirculatory Dysfunction in Cardiogenic Shock

Author

Rahman, S., primary, Baranowska, J., additional, Lee, C., additional, Miller, T., additional, Moeller, C., additional, Fernandez Valledor, A., additional, Oren, D., additional, Rubinstein, G., additional, Rahman, A., additional, Raikhelkar, J., additional, Bae, D., additional, Oh, K., additional, DeFilippis, E., additional, Lotan, D., additional, Topkara, V., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Kaku, Y., additional, Takeda, K., additional, Clerkin, K., additional, Majure, D., additional, Burkhoff, D., additional, Sayer, G., additional, Fried, J., additional, and Uriel, N., additional

Published
2024
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36. Should Living Alone be an Absolute Contraindication to HeartMate 3 Implantation: A Single Center Experience

Author

Ladanyi, A., primary, Shahidi, C., additional, Calì, F., additional, Carey, M.R., additional, Deluty, S., additional, Mondellini, G.M., additional, Pinsino, A., additional, Feldman, V.R., additional, Sayer, G., additional, Kaku, Y., additional, Uriel, N., additional, Takeda, K., additional, Colombo, P.C., additional, and Yuzefpolskaya, M., additional

Published
2024
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37. Molecular Microscope (MMDx) Results in the Sensitized Heart Transplant Recipient

Author

Rahman, A., primary, Moeller, C., additional, Fernandez Valledor, A., additional, Rzechorzek, W., additional, Rahman, S., additional, Baranowska, J., additional, Rubinstein, G., additional, Oren, D., additional, Lee, C., additional, Oh, K., additional, Bae, D., additional, Raikhelkar, J., additional, Lotan, D., additional, DeFilippis, E., additional, Theodoropoulos, K., additional, Fried, J., additional, Clerkin, K., additional, Latif, F., additional, Sayer, G., additional, and Uriel, N., additional

Published
2024
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38. An Analysis of ECMO Use Post-Transplant in the GUARDIAN Heart Registry

Author

Jorde, U., primary, Uriel, N., additional, Goldstein, D., additional, Patel, S., additional, Leacche, M., additional, Vidic, A., additional, Pham, S., additional, Klein, L., additional, Smith, J., additional, Jacobs, J., additional, Teuteberg, J., additional, Kawabori, M., additional, and D'Alessandro, D., additional

Published
2024
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40. Association of Sex Mismatch with Allograft Rejection After Heart Transplantation (HT) - Molecular Microscope (MMDx) Results

Author

Baranowska, J., primary, Moeller, C.M., additional, Fernandez Valledor, A., additional, Regan, M., additional, Rahman, S., additional, Lee, C., additional, Oren, D., additional, Rubinstein, G., additional, Oh, K., additional, Rahman, A., additional, Bae, D., additional, Topkara, V., additional, Yuzefpolskaya, M., additional, Raikhelkar, J., additional, Lotan, D., additional, DeFilippis, E., additional, Theodoropoulos, K., additional, Fried, J., additional, Lin, E., additional, Majure, D., additional, Clerkin, K., additional, Latif, F., additional, Colombo, P., additional, Sayer, G., additional, and Uriel, N., additional

Published
2024
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42. Clinical Utility of Molecular Microscope Diagnostic System (MMDx) in Heart Transplant Recipients: Moving Towards a New Paradigm

Author

Fernandez Valledor, A., primary, Moeller, C.M., additional, Rubinstein, G., additional, Rahman, S., additional, Baranowska, J., additional, Lee, C., additional, Oren, D., additional, Mehlman, Y., additional, Slomovich, S., additional, Lindekens, J., additional, Fuselier, B., additional, Salazar, R., additional, Hennecken, C.A., additional, DeFilippis, E.M., additional, Theodoropoulos, K., additional, Topkara, V., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Lotan, D., additional, Bae, D., additional, Lin, E., additional, Oh, K., additional, Majure, D., additional, Fried, J., additional, Raikhelkar, J., additional, Clerkin, K., additional, Latif, F., additional, Sayer, G.T., additional, and Uriel, N., additional

Published
2024
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44. Inflammatory Cardiomyopathies are Associated with Higher Rates of T-Cell Mediated Rejection. Molecular Microscope Results

Author

Valledor, A. Fernandez, primary, Moeller, C.M., additional, Shah, R., additional, Rubinstein, G., additional, Baranowska, J., additional, Oren, D., additional, Rahman, S., additional, Lee, C., additional, Rahman, A., additional, Oh, K., additional, Lotan, D., additional, DeFilippis, E.M., additional, Bae, D., additional, Clerkin, K., additional, Theodoropoulos, K., additional, Fried, J., additional, Raikhelkar, J., additional, Sayer, G.T., additional, Uriel, N., additional, and Latif, F., additional

Published
2024
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45. Impact of MTOR Inhibitors on Heart Allograft Rejection Using Tissue-Based Gene-Expression Profiling. Molecular Microscope (MMDx) Results

Author

Fernandez Valledor, A., primary, Moeller, C.M., additional, Rubinstein, G., additional, Oren, D., additional, Rahman, S., additional, Baranowska, J., additional, Lee, C., additional, Slomovich, S., additional, Lotan, D., additional, Fried, J., additional, DeFilippis, E.M., additional, Raikhelkar, J., additional, Theodoropoulos, K., additional, Latif, F., additional, Yuzefpolskaya, M., additional, Clerkin, K., additional, Sayer, G.T., additional, Uriel, N., additional, and Majure, D., additional

Published
2024
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46. Impact of Race Mismatch in Allograft Rejection After Heart Transplantation. Molecular Microscope (MMDx) Results

Author

Valledor, A. Fernandez, primary, Moeller, C.M., additional, Baranowska, J., additional, Oren, D., additional, Rubinstein, G., additional, Rahman, S., additional, Lee, C., additional, Mehlman, Y., additional, Slomovich, S., additional, Lotan, D., additional, DeFilippis, E.M., additional, Bae, D., additional, Rahman, A., additional, Shah, R., additional, Oh, K., additional, Fried, J., additional, Clerkin, K., additional, Theodoropoulos, K., additional, Sayer, G.T., additional, Uriel, N., additional, and Latif, F., additional

Published
2024
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47. Does Multiorgan Transplantation Correlate with Reduced Rates of Rejection as Evaluated by the Molecular Microscope (MMDx)?

Author

Moeller, C.M., primary, Fernandez Valledor, A., additional, Oren, D., additional, Rubinstein, G., additional, Rahman, S., additional, Baranowska, J., additional, Lee, C., additional, Raikhelkar, J., additional, DeFilippis, E.M., additional, Fried, J., additional, Lotan, D., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Clerkin, K., additional, Theodoropoulos, K., additional, Majure, D., additional, Sayer, G., additional, Uriel, N., additional, and Latif, F., additional

Published
2024
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49. Impact and Outcomes of Induction Therapy on Donor-Derived Cell-Free DNA Levels and Peripheral Gene-Expression Profiling in Heart Transplant Recipients

Author

Moeller, C.M., primary, Fernandez Valledor, A., additional, Oren, D., additional, Rahman, A., additional, Baranowska, J., additional, Lee, C., additional, Bae, D., additional, Rahman, S., additional, Regan, M., additional, DeFilippis, E., additional, Oh, K., additional, Rubinstein, G., additional, Lotan, D., additional, Yuzefpolskaya, M., additional, Clerkin, K.J., additional, Colombo, P., additional, Majure, D., additional, Fried, J., additional, Theodoropoulos, K., additional, Raikhelkar, J., additional, Latif, F., additional, Sayer, G.T., additional, and Uriel, N., additional

Published
2024
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50. LVAD Bridge to Transplant and Rejection Assessed by Molecular Microscope

Author

Rubinstein, G., primary, Fernandez Valledor, A., additional, Moeller, C.M., additional, Slomovich, S., additional, Oren, D., additional, Baranowska, J., additional, Rahman, S., additional, Lee, C., additional, Oh, K., additional, Bae, D., additional, Topkara, V., additional, Lotan, D., additional, DeFilippis, E.M., additional, Theodoropoulos, K., additional, Raikhelkar, J., additional, Fried, J., additional, Lin, E., additional, Majure, D., additional, Clerkin, K., additional, Yuzefpolskaya, M., additional, Colombo, P., additional, Sayer, G., additional, Latif, F., additional, and Uriel, N., additional

Published
2024
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