Malviya,Rishabha, Raj,Shakshi, Fuloria,Shivkanya, Subramaniyan,Vetriselvan, Sathasivam,Kathiresan, Kumari,Usha, Unnikrishnan Meenakshi,Dhanalekshmi, Porwal,Omji, Hari Kumar,Darnal, Singh,Amit, Chakravarthi,Srikumar, Kumar Fuloria,Neeraj, Malviya,Rishabha, Raj,Shakshi, Fuloria,Shivkanya, Subramaniyan,Vetriselvan, Sathasivam,Kathiresan, Kumari,Usha, Unnikrishnan Meenakshi,Dhanalekshmi, Porwal,Omji, Hari Kumar,Darnal, Singh,Amit, Chakravarthi,Srikumar, and Kumar Fuloria,Neeraj
Rishabha Malviya,1,* Shakshi Raj,1,* Shivkanya Fuloria,2,* Vetriselvan Subramaniyan,3,* Kathiresan Sathasivam,4 Usha Kumari,5 Dhanalekshmi Unnikrishnan Meenakshi,6 Omji Porwal,7 Darnal Hari Kumar,8 Amit Singh,1 Srikumar Chakravarthi,9 Neeraj Kumar Fuloria2,* 1Department of Pharmacy, SMAS, Galgotias University, Greater Noida, U.P., India; 2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Kedah, 08100, Malaysia; 3Department of Pharmacology, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Kuala Lumpur, 42610, Malaysia; 4Department of Biotechnology, Faculty of Applied Science, AIMST University, Kedah, 08100, Malaysia; 5Department of Physiology, Faculty of Medicine, AIMST University, Kedah, 08100, Malaysia; 6Department of Pharmacology, College of Pharmacy, National University of Science and Technology, Muscat, 130, Oman; 7Department of Pharmacognosy, Faculty of Pharmacy, Tishk International University, Erbil, 44001, KRG, Iraq; 8Department of Pathology, Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Johor Bahru, 80200, Malaysia; 9Department of Pathology, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Kuala Lumpur, 42610, Malaysia*These authors contributed equally to this workCorrespondence: Neeraj Kumar FuloriaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Kedah, 08100, MalaysiaTel +60 164037685Email neerajkumar@aimst.edu.myShivkanya FuloriaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Kedah, 08100, MalaysiaTel +60 143034057Email shivkanya_fuloria@aimst.edu.myPurpose: The present study was intended to fabricate chitosan (Ch)-tamarind gum polysaccharide (TGP) polyelectrolyte complex stabilized cubic nanoparticles of simvastatin and evaluate their potential against human breast cancer cell lines.Materials and Methods: The antisolvent precipitation method was used for formulation of nanoparticles. Factorial design (32) was ut