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Cancer causes approximately 10 million deaths worldwide, making it one of the leading causes of death among the world's population. Within the scientific community, it is widely recognized that cancer stem cells (CSCs) cause the tumor onset, progression, metastasis, and recurrence of cancer. Even though they only compose 0.01-2% of the cells in the tumor mass, their importance lies in the abnormal stemness property and the altered plasticity they present.

Alzheimer's disease (AD) is a neurodegenerative condition affecting millions worldwide, characterized by cognitive decline and dementia. The rising incidence of the disease and the lack of effective current treatments point to the need for alternative therapeutic strategies. Gut microbiota has emerged as a promising research avenue due to its association with AD pathology. Caloric restriction (CR), a dietary intervention involving controlled calorie reduction, has shown promising effects in extending lifespan and modulating gut microbiota.

Consumers are increasingly concerned about the impact of the foods they integrate into their diet. The intensive production of plant and animal-based foods causes environmental and ethical issues. To face this problem, the biotechnology industry is developing new production systems, supported by advances in molecular biology and the demand of consumers committed to sustainability. Precision fermentation is a technique that can reduce the production of conventional proteins by using microorganisms to produce molecules such as proteins, enzymes, and colorants.

The connection between the brain and the gut has been the subject of research for decades, but in recent years, the involvement of the gut microbiota in gut-brain communication has become the focus of scientific interest.

The standard course of treatment for glioblastoma (De Stupp protocol) consists of tumor resection followed by radiation with contemporaneous and adjuvant temozolomide administration. During their initial post-radiation magnetic resonance imaging (MRI), 20-30% of patients manifest enhanced contrast that gradually goes away without modifying treatment. This condition, known as pseudoprogression (PP) or therapy-induced necrosis makes difficult to determine tumor advancement non-invasively right away once radiotherapy is finished.

El Cáncer de mama triple negativo (CMTN) es un subtipo de cáncer muy agresivo que representa aproximadamente un 15% de todos los casos de cáncer de mama. Se caracteriza por la ausencia de receptores hormonales de estrógenos, progesterona y del receptor HER2. Esta escasez, deja a los pacientes con opciones limitadas de tratamiento y alto riesgo de recaída.

The main objective is to explore the link between Epstein-Barr virus (EBV) and multiple sclerosis (MS) and how the virus may be contributing to the disease.

The amyloid state is commonly associated with various neurodegenerative diseases, but there are also functional amyloids involved in biological processes. Amyloid fibers possess properties such as mechanical strength and self-assembly, which are of interest for the development of bioinspired materials. Applications will be explored in the environmental, biomedical, and biosensor development fields, including structures such as hydrogels, nanospheres, and fibers, to better understand the potential of these technologies and the benefits they can bring in terms of sustainability, health, and technology.

The Polycomb proteins (PcG) are important epigenetic regulators involved in gene repression. They form Polycomb Repressive Complexes (PRC) with various subunits.

Synthetic biology is a rapidly evolving field that aims to design new biological systems (creating a chassis) or improve those already present in nature

Conte infantil sobre el fartet (espècie en perill d'extinció) recomanat per a nens de 6 a 8 anys.

The aim of the present work is to cover a 1 % of the current market for meat substitutes in Amsterdam, so production will be 7 metric tons of cultured meat per year.

Currently, standard therapy for GBM consists of tumour resection followed by radiotherapy and concomitant TMZ which remains insufficient to mitigate the disease's deadly effects. Therefore, it has been promoted the development of alternate immunotherapies, such as oncolytic virotherapies, that are emerging as a safe and feasible treatments for a variety of malignancies.

Premi Arcadi Oliveres a Treballs de Fi de Grau de Transformació per a la Justícia Global de la Fundació Autònoma Solidària (FAS). 6a Edició, curs 2021/2022 Microbial electrosynthesis (MES) relies on microorganisms as catalysts for the anoxic reduction of organic compounds at the cathode, CO2 in this study, at the expense of oxidizing reactions performed at the anode. Due to the oxidized nature of the carbon molecule, external energy must be supplied for the reaction to be favourable. In a nutshell, MES can decrease surplus CO2 in the environment while synthesizing value-added compounds.

La proposta d'aquest material divulgatiu va enfocada a facilitar la comprensió de la Biotecnologia i despertar l'interès d'un públic no especialitzat, a través de l'adaptació del conte d'Alicia al País de les Meravelles de Lewis Carroll. Aquest treball es va exposar a la Biblioteca de Ciència i Tecnologia durant l'abril i maig de 2022.

New therapies such as bacteriophage therapy are needed to fight life-threatening infections as antibiotic therapy is progressively more limited due to resistance emergence. Phages and bacteria have co-evolved for ages so even though we know bacteria naturally develop resistance against phage infection, so do phages through counteradaptation mechanisms.

This work will broaden the current knowledge regarding rhizosphere ecology, through the identified strains adjunct to chickpea cultivation, and biofertilizer application, since no published comparison between filling materials exists, while developing an applicable integrated solution to mitigate salt stress in chickpea cultivars in the Spanish peninsula.

The generation of M. genitalium isogenic strains bearing selected point mutations in different locations of subunit A topoisomerase IV gene (parC) will help to determine the contribution of this gene to the origin of fluoroquinolone resistance phenotypes found in natural isolates of this microorganism.

Premi UAB de la Fundació Autònoma Solidària (FAS) als millors Treballs de Fi de Grau sobre desenvolupament sostenible i justícia global. 5a Edició, curs 2020/2021

Premi UAB de la Fundació Autònoma Solidària (FAS) als millors Treballs de Fi de Grau sobre desenvolupament sostenible i justícia global. 5a Edició, curs 2020/2021

The aim of this review is to expose an insight into the suitability of the use of antimicrobial peptides as an alternative to antibiotics in the treatment of S. aureus infections, one of the most commonly bacteria developing AMR.