72 results on '"Université de Pise"'
Search Results
2. Link resource adaptation for multiantenna bit-interleaved coded multicarrier systems
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UCL - SST/ICTM/ELEN - Pôle en ingénierie électrique, Université de Pise - Communication Dpt, Stupia, Ivan, Lottici, V., Giannetti, F., Vandendorpe, Luc, UCL - SST/ICTM/ELEN - Pôle en ingénierie électrique, Université de Pise - Communication Dpt, Stupia, Ivan, Lottici, V., Giannetti, F., and Vandendorpe, Luc
- Abstract
The availability of flexible radio interfaces capable of adapting their configuration to the time-varying operating environment is the key response to the demand encountered in modern wireless networks for high data rates under strict quality of service (QoS) constraints. To this end, this paper develops a novel link resource adaptation (LRA) scheme for soft-decoded multiantenna (MIMO) bit interleaved coded orthogonal frequency division multiplexing (BIC-OFDM) transmissions employing automatic repeat request (ARQ) mechanisms. As the first step, a simple link performance evaluation model based on the effective signal-to-noise ratio (SNR) mapping concept is derived in a closed-form expression that it is shown to yield better accuracy than previous techniques. Then, an effective LRA strategy is formulated taking advantage of that framework. The aim is maximizing the goodput (GP) metric, that is to say, the number of information bits delivered without error to the user by unit of time, over the available radio resources, such as the power distribution on the subchannels, coding rate, modulation order and the MIMO configuration. The numerical results demonstrate considerable performance gains compared with nonadaptive transmissions, while keeping the computational complexity at affordable levels in view of the specific structure of the GP objective function. © 2012 IEEE.
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- 2012
3. Literary interview and truth. How does Christine Angot reveal the author's truth in her media performances?
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Sini, Lorella, Merger, Marie-France, Université de Pise, and Université de Pise - Italie
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[SHS]Humanities and Social Sciences - Abstract
International audience; The different “ethos” displayed by Christine Angot emerge in a subtle play of interdiscursive relationships that are created throughout the literary interview. Like in a game of mirrors, the self-images she projects can be deconstructed into four paradoxical and ambiguous facets. The quadruple nature of the author’s image allows us to define the literary identity of Christine Angot. She strives to demonstrate that the truth of the text should not be confused with the reality of facts, and that the former can in no way be interpreted as a true copy of the latter, despite the staging of a character called Christine Angot, her homonymous double.; Les différents ethé que donne à voir C. Angot apparaissent dans un jeu subtil de relations interdiscursives qui se tissent au cours de l’entretien littéraire. Les images de soi qu’elle projette peuvent se décomposer, comme dans un agencement de miroirs, en quatre facettes paradoxales et ambiguës. Cette quadruple nature de l’image d’auteure nous permet de cerner l’identité littéraire de C. Angot. Cette dernière s’évertue à démontrer que la vérité du texte ne doit pas être confondue avec la réalité des faits, que la première ne peut en aucun cas être interprétée comme une copie conforme de la seconde et ce, malgré la mise en scène d’un personnage dénommé Christine Angot, son double homonyme.
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- 2020
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4. A consistent energy-based cohesive zone model to simulate delamination between differently oriented plies
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Mathilde Zani, Daniele Fanteria, Anita Catapano, Marco Montemurro, Institut de Mécanique et d'Ingénierie (I2M), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), and Université de Pise
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Finite element method ,02 engineering and technology ,Fracture toughness ,Interface ,Cohesive zone model ,Damage ,Delamination ,021001 nanoscience & nanotechnology ,Computer Science::Numerical Analysis ,[SPI.MAT]Engineering Sciences [physics]/Materials ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Ceramics and Composites ,0210 nano-technology ,Civil and Structural Engineering - Abstract
A consistent energy-based cohesive zone model to simulate the mode I delamination behaviour of Fully-Uncoupled Multi-Directional (FUMD) laminates is presented in this study. The proposed energy-based approach allows determining a more general constitutive response of the cohesive interface to better match the experimental results. The constitutive behaviour of the interface is implemented in a standard finite elements (FE) code by means of a user-defined subroutine. To perform the simulations, FE models of a Double Cantilever Beam (DCB) specimen are developed with standard and multidirectional interfaces. The results of the simulations are compared to the experimental ones in terms of force–displacement curves and crack front shape to assess the effectiveness of the proposed model. The comparison shows that the numerical simulations can closely replicate the opening delamination behaviour of DCB specimens during propagation and, in particular, they capture quite well the shape of the delamination fronts with some differences: numerical delamination fronts are characterised by a curvature lower than the one of the experimental counterparts, especially towards the specimen edges. Simulations carried out for different initial delamination lengths confirmed that the delamination changes its front shape at the very beginning of the propagation, then the front remains unaltered. The length of the transition zone for the shape of the delamination front has been found to be much lower than the specimen width.
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- 2022
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5. Dietary practices of the first Mediterranean farmers: producing, storing, preparing and consuming foodstuffs in the Neolithic period. Food & History, 19/1-2, Brespols, 334p
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Julien Vieugué, Niccolò Mazzucco, Centre National de la Recherche Scientifique (CNRS), Université de Pise, and VIEUGUE, Julien
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[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2021
6. Haine et (re)médiations
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Fracchiolla, Béatrice, Hugonnier, Claire, ROMAIN, CHRISTINA, Centre de Recherche sur les Médiations (Crem), Université de Lorraine (UL), Laboratoire d'Etudes de Genre et de Sexualité (LEGS), Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Centre National de la Recherche Scientifique (CNRS), LInguistique et DIdactique des Langues Étrangères et Maternelles (LIDILEM), Université Grenoble Alpes (UGA), Laboratoire Parole et Langage (LPL), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, and Centre National de la Recherche Scientifique (CNRS)-Université Paris Nanterre (UPN)-Université Paris 8 Vincennes-Saint-Denis (UP8)
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[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience; Constituant aujourd’hui une réponse privilégiée à la prolifération de la haine, les campagnes de prévention émanant des instances gouvernementales sont nombreuses et multiples depuis ces dernières années — en témoigne, la Semaine d’éducation et d’actions contre le racisme et l’antisémitisme, initiée en 2016 par le Ministère de l’Éducation Nationale. Les objectifs de ce dispositif sont de « sensibiliser les élèves des écoles, collèges et lycées, à la prévention du racisme, de l’antisémitisme et de toutes les formes de discriminations », tout en faisant « acquérir par tous les élèves le respect de l’égale dignité des êtres humains, quelles que soient leurs origines, leurs conditions, leurs convictions »1. Les supports proposés sont alors présentés comme des ressources alternatives aux comportements haineux, susceptibles d’être utilisées, notamment en formation avec des jeunes, pour faciliter l’échange et la discussion, la réflexivité et la transformation des points de vue. Or, cette campagne n’a pas fait l’unanimité, et les réactions négatives ont été nombreuses sur les réseaux sociaux, et particulièrement virulentes, se rattachant à des orientations idéologiques opposées. Ce dispositif initialement proposé pour enrayer la prolifération de la haine, a en réalité été son moteur, prenant la forme d’un contre-discours participant à la montée en tension. Ces éléments témoignent donc de toute la complexité d’ériger un discours en réponse à la haine et d’établir des modalités de (re)médiations efficaces. À travers l’analyse de dispositifs déjà existants accompagnés de corpus qui seront soumis à l’analyse des participants, cet atelier propose : 1. de faire réfléchir aux différentes stratégies discursives mises en place pour lutter contre la haine, 2. de penser les caractéristiques et les spécificités d’un discours alternatif et d’un contre-discours 3. de saisir les enjeux et les liens complexes que les deux genres discursifs entretiennent avec le discours haineux.
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- 2021
7. Expansion and Specialization of Agricultural Systems in Western Mediterranean Areas: A Global Analysis Based on the Two Last Census Data
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Marya Rabelo, Tiziana Sabbatini, Marta Debolini, R. Villani, Nicola Silvestri, Université de Pise, Environnement Méditerranéen et Modélisation des Agro-Hydrosystèmes (EMMAH), Avignon Université (AU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institute of Life Sciences of Sant’Anna [Pisa], and Scuola Universitaria Superiore Sant'Anna [Pisa] (SSSUP)
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Mediterranean climate ,010504 meteorology & atmospheric sciences ,0211 other engineering and technologies ,[SDV.SA.AGRO]Life Sciences [q-bio]/Agricultural sciences/Agronomy ,Agricultural system distribution ,Agricultural system trajectories ,Agricultural typology ,Land cover ,Land use ,02 engineering and technology ,Spatial distribution ,01 natural sciences ,agricultural system distribution ,Agricultural science ,land cover ,agricultural system trajectories ,0105 earth and related environmental sciences ,2. Zero hunger ,business.industry ,Fragmentation (computing) ,land use ,021107 urban & regional planning ,Agriculture ,15. Life on land ,Census ,Geography ,Arable land ,business ,Agronomy and Crop Science ,agricultural typology - Abstract
The study aims to describe and interpret the agricultural system dynamics on the Western Mediterranean areas in terms of occupied land and crop specialization, by using the available data from the two last agricultural censuses. From the spatial point of view, we chose to adopt the most detailed level available, by using the smallest land administrative unit (LAU) for every involved country (Spain, Portugal, France and Italy). The resulting database was made of about 16k records and seven fields for a total of 112k single data. The considered variables were: total farm area (TFA), utilized agricultural area (UAA), irrigated area (IA), arable lands (AL), permanent crops (PC), permanent grassland (PG) and remaining surface (RS). The LAU data analysis was carried out following the four steps: (i) level of land occupation by agricultural systems, (ii) patterns of crop groups in UAA composition, (iii) attribution to each LAU of an agricultural typology (AT), resulting from the combination of the two previous features and iv) calculation of two synthetic indices to evaluate the expansion and specialization level for each LAU. Finally, an analysis of the spatial distribution of the two indices was proposed. Results showed a lowering over time of the TFA, UAA and PG areas and an increase of IA and RS. The number of identified ATs was rising at the expense of their extension. This phenomenon led to a fragmentation in ATs spatial distribution within the same geographical region. These changes prove that farmers’ responses to the driving forces acting on agricultural systems have been more differentiated than in the past. The prevailing strategy seems to aim at a reduction in the level of specialization of the agricultural systems whereas less marked was the lowering of their level of expansion.
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- 2021
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8. Finding a Way Out of the Anthropocene: The Theory of ‘Radical Needs’ and the Ecological Transition
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Razmig Keucheyan, Centre Émile Durkheim (CED), Sciences Po Bordeaux - Institut d'études politiques de Bordeaux (IEP Bordeaux)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB), Université de Pise, and Jenart, Karine
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anthropocene ,050402 sociology ,[SHS.SOCIO] Humanities and Social Sciences/Sociology ,Planned obsolescence ,0603 philosophy, ethics and religion ,12. Responsible consumption ,Politics ,0504 sociology ,Anthropocene ,Marxist philosophy ,Sociology ,theory ,ComputingMilieux_MISCELLANEOUS ,[SHS.SOCIO]Humanities and Social Sciences/Sociology ,Consumerism ,Ecology ,05 social sciences ,06 humanities and the arts ,Capitalism ,Political ecology ,[SHS.SCIPO]Humanities and Social Sciences/Political science ,radical needs ,ecological transition ,Financialization ,060301 applied ethics ,ecology ,[SHS.SCIPO] Humanities and Social Sciences/Political science - Abstract
Through advertisement, planned obsolescence, and the financialization of daily life, capitalism constantly creates ‘artificial’ needs. These needs are not only alienating for individuals, they are also unsustainable from an ecological standpoint, because they encourage consumerism, which puts excessive pressure on ecosystems. They are at the root of the environmental crisis. Hence, transitioning to a sustainable, postcapitalist, society implies, among other things, being able to separate ‘real’ from ‘artificial’ needs. This article reflects on this inextricably theoretical and political challenge. To do so, it elaborates a ‘Marxist theory of needs’, drawing from insights from Marx himself, Agnes Heller and Andre Gorz. It concludes with a few reflections on the actuality of the Marxist theory of needs for our present political conjuncture. The concept of need is not only an analytical tool, it is also a political one.
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- 2021
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9. Témoignages archéologiques et géologiques de l’évolution du niveau de la mer à partir de l’époque romaine : nouvelles données dans les Bouches de Bonifacio
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Franca Cibecchini, Laurent Borel, Marie-Brigitte Carre, Matteo Vacchi, Matthieu Ghilardi, Borel, Laurent, Département des Recherches Archéologiques Subaquatiques et Sous-Marines [Marseille] (DRASSM), Ministère de la Culture (MC), Centre Camille Jullian - Histoire et archéologie de la Méditerranée et de l'Afrique du Nord de la protohistoire à la fin de l'Antiquité (CCJ), Aix Marseille Université (AMU)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, Centre européen de recherche et d'enseignement des géosciences de l'environnement (CEREGE), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Collège de France (CdF (institution))-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD), GIS d’Histoire & Sciences de la mer, PCR « Les Bouches de Bonifacio à l’époque romaine :approches archéologiques et géoarchéologique », University of Pisa - Università di Pisa, and Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
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[SDE] Environmental Sciences ,[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,Niveau marin ,[SDE]Environmental Sciences ,Granite ,Archéologie maritime et littorale ,Piantarella ,Carrières ,Cavallo ,Corse du Sud ,Géologie ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2021
10. Mise en scène d’un discours de résistance: 'En guerre' de Stéphane Brizé
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Sini, Lorella, En, Guerre, De, Stephane, and Université de Pise - Italie
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[SHS.LANGUE]Humanities and Social Sciences/Linguistics - Abstract
International audience; Nous étudierons à travers quelques scènes du film français En guerre de Stéphane Brizé (2018) les caractéristiques d’un certain type de discours alternatif qui pourrait se définir plus précisément comme un discours de résistance. Celui-ci est représenté dans un espace polarisé et antagonique où deux camps s’affrontent dans une stratégie discursive de rupture. Il s’exprime à travers l’ethos d’un meneur, un charisme qui est susceptible de construire une identité collective. Enfin nous proposerons quelques réflexions sur l’impossibilité du consensus qui donne lieu à l’émergence de la violence verbale, voire de la violence physique.
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- 2020
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11. A Study on Force-based Collaboration in Swarms
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Chiara Gabellieri, Antonio Franchi, Marco Tognon, Dario Sanalitro, Lucia Pallottino, Université de Pise, Équipe Robotique et InteractionS (LAAS-RIS), Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, University of Pisa - Università di Pisa, Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), and ANR-17-CE33-0007,MUROPHEN,Controle de systèmes multi-robots pour l'observation de phenomenes dynamiques(2017)
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0209 industrial biotechnology ,Computer science ,Admittance-controlled robots ,Aerial robotic co-manipulation ,Communication-less coordination ,Multi-robot manipulation ,Stability (learning theory) ,Swarm behaviour ,Control engineering ,02 engineering and technology ,Object (computer science) ,Contact force ,020901 industrial engineering & automation ,Artificial Intelligence ,Robustness (computer science) ,[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA] ,Scalability ,0202 electrical engineering, electronic engineering, information engineering ,[INFO.INFO-SY]Computer Science [cs]/Systems and Control [cs.SY] ,Software design ,Robot ,[INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO] ,020201 artificial intelligence & image processing - Abstract
International audience; Cooperative manipulation is a basic skill in groups of humans, animals , and in many robotic applications. Besides being an interesting challenge, communication-less approaches have been applied to groups of robots in order to achieve higher scalability and simpler hardware and software design. We present a generic model and control law for robots cooperatively manipulating an object, for both ground and floating systems. The control method exploits a leader-follower scheme and is based only on implicit communication (i.e., the sensing of contact forces). The control objective mainly consists of steering the object manipulated by the swarm of robots to a desired position and orientation in a cooperative way. For a system with just one leader, we present analytical results on the equilibrium configurations and their stability that are then validated by numerical simulations. The role of object internal forces (induced by the robots through contact forces) is discussed in terms of convergence of the object position and orientation to the desired values. We also present a discussion on additional properties of the controlled system that were investigated using thorough numerical analysis, namely, the robustness of the system when the object is subject to external disturbances in non-ideal conditions , and how the number of leaders in the swarm can affect the aforementioned convergence and robustness.
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- 2020
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12. Multi-Scale Least-Weight Design of a Wing-Box via a Global/Local Approach
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PANETTIERI, Enrico, Montemurro, Marco, FANTERIA, Daniele, COCCIA, Francesco, Institut de Mécanique et d'Ingénierie (I2M), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), and Université de Pise
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[SPI.MECA.STRU]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Structural mechanics [physics.class-ph] ,Mécanique: Mécanique des solides [Sciences de l'ingénieur] ,[MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC] ,[SPI.MECA.SOLID]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Solid mechanics [physics.class-ph] ,Optimisation et contrôle [Mathématique] ,Mécanique: Mécanique des structures [Sciences de l'ingénieur] - Abstract
International audience; In this work, a multi-scale optimization strategy for lightweight structures, based on a global-local modelling approach is presented. The approach is applied to a realistic wing structure of a civil aircraft. The preliminary design of the wing can be formulated as a constrained optimization problem, involving several requirements at the different scales of the structure. The proposed strategy is characterized by two main features. Firstly, the problem is formulated in the most general sense, by including all design variables involved at each problem scale. Secondly, two scales are considered: (i) the structure macroscopic scale, where low-fidelity numerical models are used; (ii) the structure mesoscopic scale (or component-level), where enhanced models are involved. In particular, the structural responses are evaluated at both global and local scales, avoiding the use of approximated analytical methods. To this end, fully parametric global and local finite element models are interfaced with an in-house genetic algorithm. Refined models are created only for the most critical regions of the structure, and linked to the global one by means of a dedicated sub-modelling approach.
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- 2020
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13. Design and finite element assessment of fully uncoupled multi-directional layups for delamination tests
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Eric Martin, Anita Catapano, Torquato Garulli, Daniele Fanteria, Julien Jumel, Université de Pise, Institut de Mécanique et d'Ingénierie (I2M), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), CEA Le Ripault (CEA Le Ripault), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université de Bordeaux (UB), Laboratoire des Composites Thermostructuraux (LCTS), Centre National de la Recherche Scientifique (CNRS)-Snecma-SAFRAN group-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), University of Pisa - Università di Pisa, Institut de Mécanique et d'Ingénierie de Bordeaux (I2M), Institut National de la Recherche Agronomique (INRA)-Université de Bordeaux (UB)-École Nationale Supérieure d'Arts et Métiers (ENSAM), Arts et Métiers Sciences et Technologies, HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Arts et Métiers Sciences et Technologies, HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), and Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut de Chimie du CNRS (INC)-Snecma-SAFRAN group-Centre National de la Recherche Scientifique (CNRS)
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Materials science ,Mechanical Engineering ,Delamination ,Stacking ,02 engineering and technology ,finite element analysis ,[CHIM.MATE]Chemical Sciences/Material chemistry ,021001 nanoscience & nanotechnology ,Finite element method ,delamination ,fracture toughness ,[SPI.MAT]Engineering Sciences [physics]/Materials ,020303 mechanical engineering & transports ,Fracture toughness ,0203 mechanical engineering ,Laminates ,Mechanics of Materials ,Multi directional ,Materials Chemistry ,Ceramics and Composites ,Composite material ,0210 nano-technology - Abstract
International audience; In this paper, a procedure to obtain fully uncoupled multi-directional stacking sequences for delamination specimens is outlined. For such sequences, in-plane, membrane-bending and torsion–bending coupling terms are null (in closed-form solution in the framework of classical laminated plate theory) for the entire stack and for both its halves, which form two arms in the pre-cracked region of a typical delamination specimen. This is achieved exploiting the superposition of quasi-trivial quasi-homogeneous stacking sequences, according to appropriate rules. Any pair of orientations of the plies embedding the delamination plane can be obtained. To assess the effectiveness of the proposed approach, a fully uncoupled multi-directional sequence is designed and compared to other relevant sequences proposed in the literature. Finite element simulations of double cantilever beam test are performed using classic virtual crack closure technique and a revised state-of-the-art virtual crack closure technique formulation too. Some interesting conclusions regarding proper design of multidirectional stacks for delamination tests are drawn. Moreover, the results confirm the suitability of fully uncoupled multi-directional sequences for delamination tests. Thanks to their properties, these sequences might lay the foundations for the development of standard test procedures for delamination in angle-ply interfaces.
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- 2020
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14. Multi-scale optimisation of thin-walled structures by considering a global/local modelling approach
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Daniele Fanteria, Michele Iacopo Izzi, Anita Catapano, Marco Montemurro, Jérôme Pailhès, Institut de Mécanique et d'Ingénierie de Bordeaux (I2M), Institut National de la Recherche Agronomique (INRA)-Université de Bordeaux (UB)-École Nationale Supérieure d'Arts et Métiers (ENSAM), Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), Université de Pise, and This paper presents part of the activities carried out within the research project PARSIFAL (Prandtlplane ARchitecture for the Sustainable Improvement of Future AirpLanes), which has been funded by the European Union under the Horizon 2020 Research and Innovation Program (Grant Agreement n.723149)
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Work (thermodynamics) ,Scale (ratio) ,Computer science ,stiffened panels ,finite element method ,Aerospace Engineering ,Mechanical engineering ,Thin walled ,02 engineering and technology ,Design strategy ,[SPI.MECA.SOLID]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Solid mechanics [physics.class-ph] ,genetic algorithms ,0203 mechanical engineering ,Optimisation ,Mécanique: Mécanique des structures [Sciences de l'ingénieur] ,fuselage ,Mechanical Engineering ,Global local ,Mécanique: Mécanique des solides [Sciences de l'ingénieur] ,Optimisation et contrôle [Mathématique] ,021001 nanoscience & nanotechnology ,Finite element method ,global/local modelling approach ,020303 mechanical engineering & transports ,[SPI.MECA.STRU]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Structural mechanics [physics.class-ph] ,[MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC] ,0210 nano-technology - Abstract
International audience; In this work, a design strategy for optimising thin-walled structures based on a global-local finite element (FE) modelling approach is presented. The preliminary design of thin-walled structures can be stated in the form of a constrained non-linear programming problem (CNLPP) involving requirements of different nature intervening at the different scales of the structure. The proposed multi-scale optimisation (MSO) strategy is characterised by two main features. Firstly, the CNLPP is formulated in the most general sense by including all design variables involved at each pertinent scale of the problem. Secondly, two scales (with the related design requirements) are considered: (a) the structure macroscopic scale, where low-fidelity FE models are used and (b) the structure mesoscopic scale (or component level), where more accurate FE models are involved. In particular, the mechanical responses of the structure are evaluated at both global and local scales, avoiding the use of approximated analytical methods. The MSO is here applied to the least-weight design of an aluminium fuselage barrel of a wide-body aircraft. Fully parametric global and local FE models are interfaced with an in-house metaheuristic algorithm. Refined local FE models are created only for critical regions of the structure, automatically detected during the global analysis, and linked to the global one, thanks to the implementation of a sub-modelling approach. The whole process is completely automated, and once set, it does not need any further user intervention.; In this work, a design strategy for optimising thin-walled structures based on a global-local finite element (FE) modelling approach is presented. The preliminary design of thin-walled structures can be stated in the form of a constrained non-linear programming problem (CNLPP) involving requirements of different nature intervening at the different scales of the structure. The proposed multi-scale optimisation (MSO) strategy is characterised by two main features. Firstly, the CNLPP is formulated in the most general sense by including all design variables involved at each pertinent scale of the problem. Secondly, two scales (with the related design requirements) are considered: i) the structure macroscopic scale, where low-fidelity FE models are used; ii) the structure mesoscopic scale (or component-level), where more accurate FE models are involved. In particular, the mechanical responses of the structure are evaluated at both global and local scales, avoiding the use of approximated analytical methods. The MSO is here applied to the least-weight design of an aluminium fuselage barrel of a wide-body aircraft. Fully parametric global and local FE models are interfaced with an in-house metaheuristic algorithm. Refined local FE models are created onlyfor critical regions of the structure, automatically detected during the global analysis, and linked to the global one thanks to the implementation of a sub-modelling approach. The whole process is completely automated and, once set, it does not need any further user intervention.
- Published
- 2020
- Full Text
- View/download PDF
15. SEMANTIC ANNOTATIONS ON HERITAGE MODELS: 2D/3D APPROACHES AND FUTURE RESEARCH CHALLENGES
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L. De Luca, Valeria Croce, Gabriella Caroti, Philippe Veron, Andrea Piemonte, Modèles et simulations pour l'Architecture et le Patrimoine (MAP), Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, Laboratoire d’Ingénierie des Systèmes Physiques et Numériques (LISPEN), Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), Centre National de la Recherche Scientifique (CNRS), and École Nationale Supérieure des Arts et Métiers (ENSAM)
- Subjects
lcsh:Applied optics. Photonics ,H-BIM ,010504 meteorology & atmospheric sciences ,Process (engineering) ,Computer science ,[SHS.INFO]Humanities and Social Sciences/Library and information sciences ,Ingénierie assistée par ordinateur [Informatique] ,Cloud computing ,02 engineering and technology ,Artifact (software development) ,Representation (arts) ,Cultural Heritage ,01 natural sciences ,lcsh:Technology ,Field (computer science) ,semantic annotation ,Sciences de l'information et de la communication [Sciences de l'Homme et Société] ,11. Sustainability ,0202 electrical engineering, electronic engineering, information engineering ,Information system ,2D/3D mapping ,A oli ,Semantic annotation ,0105 earth and related environmental sciences ,business.industry ,lcsh:T ,lcsh:TA1501-1820 ,020207 software engineering ,[INFO.INFO-IA]Computer Science [cs]/Computer Aided Engineering ,Data science ,Term (time) ,Cultural heritage ,lcsh:TA1-2040 ,business ,lcsh:Engineering (General). Civil engineering (General) - Abstract
Research in the field of Cultural Heritage is increasingly moving towards the creation of digital information systems, in which the geometric representation of an artifact is linked to some external information, through meaningful tags. The process of attributing additional and structured information to various elements in a given digital model is customarily identified with the term semantic annotation; the added contextual information is associated, for instance, to analysis and conservation terms. Starting from the existing literature, aim of this work is to discuss how semantic annotations are used, in digital architectural heritage models, to link the geometrical representation of an artefact with knowledge-related information. Most consolidated methods -such as traditional mapping on 2D media, are compared with more recent approaches making the most of 3D representation. Reference is made, in particular, to Heritage-BIM techniques and to collaborative reality-based platforms, such as Aïoli (http://aioli.cloud). Potentialities and limits of the different solutions proposed in literature are critically discussed, also addressing future research challenges in Cultural Heritage application fields.
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- 2020
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16. Speleothem-inferred paleoclimate records at 570-450 thousand years ago from northern Mediterranean
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Chien, Wei-Yi, Hu, Hsun-Ming, Asami, Ryuji, Kano, Akihiro, Mii, Horng-Sheng, Michel, Véronique, Valensi, Patricia, Elisabetta, Starnini, Chou, Yu-Min, Iryu, Yasufumi, Takayanagi, Hideko, Tsai, Hsien-Chen, Sung, Wen-Hui, Yu, Tsai-Luen, Shen, Chuan-Chou, High-Precision Mass Spectrometry and Environment Change Laboratory (HISPEC), National Taiwan University [Taiwan] (NTU), Institut of Geology and Paleontology, Graduate School of Science, Tohoku University, Department of Earth and Planetary Science [Tokyo], The University of Tokyo (UTokyo), Department of Earth Sciences [NTNU Taipei], National Taiwan Normal University (NTNU), Culture et Environnements, Préhistoire, Antiquité, Moyen-Age (CEPAM), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Histoire naturelle de l'Homme préhistorique (HNHP), Muséum national d'Histoire naturelle (MNHN)-Université de Perpignan Via Domitia (UPVD)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, Center of Marine Magnetism, Department of Ocean Science and Engineering, Graduate School of Science [Tokyo], The University of Tokyo (UTokyo)-The University of Tokyo (UTokyo), and Michel, Veronique
- Subjects
[SDU] Sciences of the Universe [physics] ,[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,[SDU]Sciences of the Universe [physics] ,[SHS] Humanities and Social Sciences ,ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
- Published
- 2019
17. Northern Mediterranean precipitation variation and orbital forcing on westerlies over the past 250-400 thousand years ago
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Sung, Wen-Hui, Hu, Hsun-Ming, Kano, Akihiro, Asami, Ryuji, Iryu, Yasufumi, Takayanagi, Hideko, Mii, Horng-Sheng, Michel, Véronique, Valensi, Patricia, Marta, Zunino, Elisabetta, Starnini, Chou, Yu-Min, Tsai, Hsien-Chen, Chien, Wei-Yi, Yu, Tsai-Luen, Shen, Chuan-Chou, High-Precision Mass Spectrometry and Environment Change Laboratory (HISPEC), National Taiwan University [Taiwan] (NTU), Culture et Environnements, Préhistoire, Antiquité, Moyen-Age (CEPAM), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Histoire naturelle de l'Homme préhistorique (HNHP), Muséum national d'Histoire naturelle (MNHN)-Université de Perpignan Via Domitia (UPVD)-Centre National de la Recherche Scientifique (CNRS), Dipartimento Scienze della Terra, Università degli Studi di Torino, Université de Pise, and Michel, Veronique
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[SDU] Sciences of the Universe [physics] ,[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,[SDU]Sciences of the Universe [physics] ,[SHS] Humanities and Social Sciences ,ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
- Published
- 2019
18. Least-weight composite plates with unconventional stacking sequences: Design, analysis and experiments
- Author
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Jalal El-Yagoubi, Daniele Fanteria, Michele Iacopo Izzi, Marco Montemurro, Institut de Mécanique et d'Ingénierie (I2M), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), Université de Pise, and PARSIFAL (Prandtlplane ARchitecture for the Sustainable Improvement of Future AirpLanes) project. Grant Agreement n. 723149
- Subjects
Design analysis ,Materials science ,Composite number ,finite element method ,Stacking ,02 engineering and technology ,[SPI.MECA.MSMECA]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Materials and structures in mechanics [physics.class-ph] ,[SPI.MECA.SOLID]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Solid mechanics [physics.class-ph] ,0203 mechanical engineering ,buckling ,Composites ,genetic algorithm ,lightweight structures ,multi-scale optimisation ,Materials Chemistry ,Composite material ,Mécanique: Mécanique des structures [Sciences de l'ingénieur] ,business.industry ,Mechanical Engineering ,Mécanique: Mécanique des solides [Sciences de l'ingénieur] ,Mécanique: Matériaux et structures en mécanique [Sciences de l'ingénieur] ,Structural engineering ,Optimisation et contrôle [Mathématique] ,021001 nanoscience & nanotechnology ,Strength of materials ,Finite element method ,020303 mechanical engineering & transports ,Buckling ,Mechanics of Materials ,[SPI.MECA.STRU]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Structural mechanics [physics.class-ph] ,Ceramics and Composites ,[MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC] ,0210 nano-technology ,business - Abstract
This study deals with the problem of the least-weight design of a composite multilayer plate subject to constraints of different nature (mechanical, geometrical and technological requirements). To face this problem, a multi-scale two-level (MS2L) design methodology is proposed. This approach aims at optimising simultaneously both geometrical and mechanical parameters of the laminate at each characteristic scale (mesoscopic and macroscopic ones). In this background, at the first level (macroscopic scale) the goal is to find the optimum value of geometrical and mechanical design variables minimising the structure mass and satisfying the set of imposed constraints (on first buckling load, membrane stiffness and feasibility constraints). The second-level problem (mesoscopic scale) aims at finding at least one stacking sequence meeting the geometrical and material parameters provided by the first-level problem. The MS2L optimisation approach is based on the polar formalism to describe the macroscopic behaviour of the composite (in the framework of the equivalent single layer theories) and on a special genetic algorithm to perform optimisation calculations. The optimum solutions provided by the MS2L optimisation strategy are characterised by a weight saving of about 10% with enhanced mechanical properties when compared to conventional symmetric balanced stacks. The effectiveness of the optimum solutions is also proven through an experimental campaign of buckling tests. The experimental results are in excellent agreement with those foreseen by the numerical simulations. PARSIFAL (Prandtlplane ARchitecture for the Sustainable Improvement of Future AirpLanes) project. Grant Agreement n. 723149
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- 2019
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19. [Compte-rendu] Lucken Michael, 2017, Le Japon grec. Culture et possession, Bibliothèque des Histoires, Gallimard, Paris, 256 p
- Author
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Taddei, Andrea and Université de Pise
- Subjects
ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
- Published
- 2019
20. Lucken Michael, 2017, Le Japon grec. Culture et possession, Bibliothèque des Histoires, Gallimard, Paris, 256 p
- Author
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Andrea Taddei and Université de Pise
- Subjects
ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
- Published
- 2019
21. A Study on Force-based Collaboration in Flying Swarms
- Author
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Antonio Franchi, Marco Tognon, Chiara Gabellieri, Lucia Pallottino, Équipe Robotique et InteractionS (LAAS-RIS), Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Université de Pise, ANR-17-CE33-0007,MUROPHEN,Controle de systèmes multi-robots pour l'observation de phenomenes dynamiques(2017), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), and University of Pisa - Università di Pisa
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0209 industrial biotechnology ,Computer science ,Distributed computing ,Work (physics) ,Swarm behaviour ,02 engineering and technology ,Physical interaction ,[INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI] ,Computer Science::Robotics ,020901 industrial engineering & automation ,Rate of convergence ,[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA] ,Stability theory ,System parameters ,0202 electrical engineering, electronic engineering, information engineering ,Robot ,[INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO] ,020201 artificial intelligence & image processing ,Internal forces - Abstract
Accepted for ANTS 2018 Eleventh International Conference on Swarm Intelligence October 29-31, 2018. Rome, Italy; International audience; This work investigates collaborative aerial transportation by swarms of agents based only on implicit information, enabled by the physical interaction among the agents and the environment. Such a coordinating mechanism in collaborative transportation is a basic skill in groups of social animals. We consider cable-suspended objects transported by a swarm of flying robots and we formulate several hypothesis on the behavior of the overall system which are validated thorough numerical study. In particular, we show that a nonzero internal force reduces to one the number of asymptotically stable equilibria and that the internal force intensity is directly connected to the convergence rate. As such, the internal force represents the cornerstone of a communication-less cooperative manipulation paradigm in swarms of flying robots. We also show how a swarm can achieve a stable transportation despite the imprecise knowledge of the system parameters.
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- 2018
22. Le négationnisme n’est pas post-moderne. Fictionnalité et fictivité de la vérité scientifique
- Author
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Wadbled, Nathanaël, Centre de Recherche sur les Médiations (Crem), Université de Lorraine (UL), Laboratoire de linguistique et didactique des langues étrangères et maternelles (Lidilem, Université Grenoble Alpes), Centro di Documentazione e di Ricerca per la Didattica della Lingua francese nell'Università italiana (Italie), Université de Pise (Italie), Université Franco-Italienne (UFI), and Hahusseau, Rudy
- Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences ,[SHS.INFO] Humanities and Social Sciences/Library and information sciences ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2018
23. Comment le faux s'impose dans le discours dominant : les relais institutionnels de la désinformation autour d'une controverse environnementale
- Author
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Stein, Marieke, Centre de Recherche sur les Médiations (Crem), Université de Lorraine (UL), Laboratoire de linguistique et didactique des langues étrangères et maternelles (Lidilem, Université Grenoble Alpes, France), Centro di Documentazione e di Ricerca per la Didattica della Lingua francese nell'Università italiana (Italie), Université de Pise (Italie), Université Franco-Italienne (UIF/UFI), Rosa Cetro, Lorella Sini, and Hahusseau, Rudy
- Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences ,[SHS.INFO] Humanities and Social Sciences/Library and information sciences - Abstract
Titre de la communication : Comment une information trompeuse s’impose dans le discours dominant : le cas d’une énergie fossile devenue "énergie verte"; International audience
- Published
- 2018
24. Discours, intox et contre-discours en controverse scientifique : l’affaire des « Portier Papers »
- Author
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Allard-Huver, François, Centre de Recherche sur les Médiations (Crem), Université de Lorraine (UL), Laboratoire de linguistique et didactique des langues étrangères et maternelles (Lidilem, Université Grenoble), Centro di Documentazione e di Ricerca per la Didattica della Lingua francese nell'Università italiana (Italie), Université de Pise (Italie), Université Franco-Italienne (UFI), Rosa Cetro, Lorella Sini, and Allard-Huver, François
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communication sensible ,Controversies ,counter-speeches ,glyphosate ,Controverses ,[SHS.INFO]Humanities and Social Sciences/Library and information sciences ,communication on sensitive issues ,contre-discours ,[SHS.INFO] Humanities and Social Sciences/Library and information sciences ,Monsanto - Abstract
In this work, we address the issue of fake news in the context of environmental, health and food controversies, particularly around the long controversy over the toxicity of Monsanto's flagship herbicide Roundup and its active molecule, glyphosate. At first glance we question misinformation and disinformation in scientific context, in particular the agonistic turn that one can observe in recent media polemics and affairs, and more recently, the use of false news in scientific controversies. Thus, we analyze the "Portier Papers", a complex undertaking implicating a researcher opposed to glyphosate, Christopher Portier. To do this, we analyze the circulation of fake news in certain media and in the pro-glyphosate sphere, as well as the construction and diffusion of spurious discourses and counter-speeches in the service of a communication on sensitive issue strategy aimed at diverting media coverage from Monsanto., Dans ce travail, nous abordons la question des fake news dans le cadre de controverses environnementales, sanitaires et alimentaires, en particulier autour de la longue controverse sur la toxicité du Roundup, l’herbicide phare de Monsanto, et de sa molécule active, le glyphosate. Nous interrogeons de prime abord les enjeux de mésinformation et désinformation en contexte scientifique, en particulier le tournant agonistique qu’on peut observer depuis quelques années dans les polémiques et les affaires, et plus récemment, l’utilisation de fausses nouvelles dans des controverses scientifiques. Nous nous intéressons ensuite aux « Portier Papers », véritable entreprise de mise en cause d’un chercheur opposé au glyphosate, Christopher Portier. Pour ce faire, nous analysons la circulation des infox dans certains médias et dans la sphère des pro-glyphosate, tout comme la construction et la diffusion de discours et contre-discours fallacieux au service d’une stratégie de communication sensible visant à détourner l’attention médiatique de Monsanto.
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- 2018
25. Mésinformation et désinformation : discours, intox et contre-discours en controverse scientifique
- Author
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Allard-Huver, François, Centre de Recherche sur les Médiations (Crem), Université de Lorraine (UL), Laboratoire de linguistique et didactique des langues étrangères et maternelles (Lidilem, Université Grenoble), Centro di Documentazione e di Ricerca per la Didattica della Lingua francese nell'Università italiana (Italie), Université de Pise (Italie), Université Franco-Italienne (UFI), and Hahusseau, Rudy
- Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences ,[SHS.INFO] Humanities and Social Sciences/Library and information sciences ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2018
26. Major cardiac and vascular complications after transvenous lead extraction: acute outcome and predictive factors from the ESC-EHRA ELECTRa (European Lead Extraction ConTRolled) registry
- Author
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Giulio Zucchelli, François Regoli, Maria Grazia Bongiorni, Luca Segreti, Christian Butter, Jean Luc Pasquié, Aldo P. Maggioni, Andrea Di Cori, Pascal Defaye, Andrzej Kutarski, Angelo Auricchio, Carina Blomström-Lundqvist, Cécile Laroche, Université de Pise, Uppsala Universitet [Uppsala], Medical University of Lublin, Cardiocentro Ticino [Lugano], Universität Zürich [Zürich] = University of Zurich (UZH), Medizinische Hochschule Brandenburg Theodor Fontane / Brandenburg Medical School Theodor-Fontane (MHB Theodor Fontane), Hôpital Michallon, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Center for Computational Medicine in Cardiology [Lugano], Università della Svizzera italiana = University of Italian Switzerland (USI), MORNET, Dominique, University of Pisa - Università di Pisa, University of Zurich, and Zucchelli, Giulio
- Subjects
Male ,Pacemaker, Artificial ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,0302 clinical medicine ,2737 Physiology (medical) ,Postoperative Complications ,Risk Factors ,Cardiac tamponade ,Occlusion ,030212 general & internal medicine ,Registries ,Incidence ,Pericardiocentesis ,Middle Aged ,Prognosis ,Thrombosis ,3. Good health ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Defibrillators, Implantable ,Europe ,Outcome and Process Assessment, Health Care ,Cardiology ,Equipment Failure ,Female ,Tamponade ,Cardiology and Cardiovascular Medicine ,Major complications ,medicine.medical_specialty ,Registry ,610 Medicine & health ,11171 Cardiocentro Ticino ,2705 Cardiology and Cardiovascular Medicine ,03 medical and health sciences ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Physiology (medical) ,Internal medicine ,medicine ,Humans ,Device Removal ,Lead extraction ,business.industry ,Avulsion fracture ,Vascular System Injuries ,medicine.disease ,Cardiac Tamponade ,Chest tube ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Complication ,business - Abstract
International audience; Aims: We aimed at describing outcomes and predictors of cardiac avulsion or tear (CA/T) with tamponade and vascular avulsion or tear (VA/T) after transvenous lead extraction (TLE) in the ESC-EHRA European Lead Extraction ConTRolled (ELECTRa) registry.Methods and results: A total of 3555 consecutive patients of whom 3510 underwent TLE at 73 centres in 19 European countries were enrolled. Among 58 patients (1.7%) with procedure-related major complications, 49 (84.5%) patients (30 CA/T and 19 VA/T) presented cardiovascular complications requiring pericardiocentesis, chest tube positioning and/or surgical repair. The mortality was 20% in patients with tamponade due to CA/T and 31.6% in patients with VA/T. Pericardiocentesis as first manoeuvre followed by rescue surgical repair was highly effective in case of CA/T (93.8%). At multivariate analysis, CA/T with tamponade was more common in RIATA lead extraction, female patients, leads with a mean dwelling time more than 10 years, and when ≥3 leads were extracted or multiple sheaths required. Occlusion or critical stenosis of superior venous access and the leads mean dwelling time more than 10 years were independent predictors for VA/T, while mechanical dilatation was an independent predictor of a lower incidence of this complication as compared to the use of powered sheaths.Conclusions: In the ELECTRa registry, RIATA lead extraction and superior venous access occlusion/thrombosis are two new independent predictors for cardiac tamponade and major vascular complications, respectively. The use of mechanical sheaths seems to be associated with a lower incidence of VA/T. A strategy of pericardiocentesis followed by a rescue surgical approach seems to be reasonable in order to treat a CA/T with tamponade.
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- 2018
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27. The Karnak Project
- Author
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Biston-Moulin, Sébastien, Thiers, Christophe, Archéologie des Sociétés Méditerranéennes (ASM), Université Paul-Valéry - Montpellier 3 (UPVM)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Centre Franco-Égyptien d'Étude des Temples de Karnak (CFEETK), Centre National de la Recherche Scientifique (CNRS), Annamaria De Santis (Université de Pise), Irene Rossi (CNR - ISMA), and Centre National de la Recherche Scientifique (CNRS)-Université Paul-Valéry - Montpellier 3 (UPVM)-Ministère de la Culture (MC)
- Subjects
Digital corpus of ancient inscriptions ,Orthophography ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Heritage conservation ,Karnak Temple ,Ancient egypt - Abstract
International audience; This article is concerned with the technical and methodological challenges encountered during a project to comprehensively document the inscriptions of the largest ancient Egyptian temple. This project aims to produce a complete inventory, and editing of, primary textual sources written in several varieties of the ancient Egyptian language and script: hieroglyphs, hieratic and demotic. The issues discussed concern the implementation of the digital tool, the need for a network of collaborators in order to process the large volume of documentation, and the need to identify digital solutions to preserve textual data from the Egyptian site. Finally, the lexicographic aspect of the project is discussed.
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- 2018
- Full Text
- View/download PDF
28. Multi-scale seasonal temperature variability and asynchronous regional hydrodynamics in Mediterranean since the middle Holocene
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Hu, Hsun-Ming, Shen, Chuan-Chou, Michel, Véronique, Valensi, Patricia, Jiang, Xiuyang, Duan, Fucai, Wang, Yongjin, Mii, Horng-Sheng, Chou, Yu-Min, Elisabetta, Starnini, High-Precision Mass Spectrometry and Environment Change Laboratory (HISPEC), National Taiwan University [Taiwan] (NTU), Culture et Environnements, Préhistoire, Antiquité, Moyen-Age (CEPAM), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Départemental de Préhistoire du Lazaret (LDPL), Département des Alpes-Maritimes, Interactions Arbres-Microorganismes (IAM), Université de Lorraine (UL)-Institut National de la Recherche Agronomique (INRA), Laboratoire Géosciences et Environnement Cergy (GEC), Fédération INSTITUT DES MATÉRIAUX DE CERGY-PONTOISE (I-MAT), Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Histoire naturelle de l'Homme préhistorique (HNHP), Muséum national d'Histoire naturelle (MNHN)-Université de Perpignan Via Domitia (UPVD)-Centre National de la Recherche Scientifique (CNRS), Center of Marine Magnetism, Department of Ocean Science and Engineering, Université de Pise, Soprintendenza Archeologia, Belle Arti e Paesaggio della Liguria (SABAP Liguria), and CEPAM, Labo
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middle ,asynchronous ,[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,Holocene ,regional ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,variability ,since ,hydrodynamics ,temperature ,Mediterranean ,seasonal ,Multi-scale - Abstract
Multi-scale seasonal temperature variability and asynchronous regional hydrodynamics in Mediterranean since the middle Holocene
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- 2018
29. Quasi-trivial stacking sequences for the design of thick laminates
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Anita Catapano, Julien Jumel, Torquato Garulli, Daniele Fanteria, Marco Montemurro, Institut de Mécanique et d'Ingénierie de Bordeaux (I2M), Institut National de la Recherche Agronomique (INRA)-Université de Bordeaux (UB)-École Nationale Supérieure d'Arts et Métiers (ENSAM), Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), Université de Pise, École Nationale Supérieure d'Arts et Métiers (ENSAM), HESAM Université (HESAM)-HESAM Université (HESAM)-Institut Polytechnique de Bordeaux-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB), and Administrateur Ensam, Compte De Service
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Work (thermodynamics) ,Class (set theory) ,Mécanique [Sciences de l'ingénieur] ,Computer science ,Stacking ,02 engineering and technology ,[SPI.MECA]Engineering Sciences [physics]/Mechanics [physics.med-ph] ,[SPI.MECA] Engineering Sciences [physics]/Mechanics [physics.med-ph] ,021001 nanoscience & nanotechnology ,Combinatorial algorithms ,Composites Laminates Quasi-trivial solutions Thick laminates Anisotropy ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Ceramics and Composites ,0210 nano-technology ,Algorithm ,Civil and Structural Engineering - Abstract
International audience; Quasi-trivial (QT) sequences have largely proven to be an extremely powerful tool in the design and optimisation of composites laminates. In this paper new interesting properties of this class of stacks are derived. These properties allow to obtain QT sequences by superposing (according to some prescribed rules) any number of QT elementary stacks. In this way, QT solutions with arbitrary large number of plies can be readily obtained, overcoming the computational issues arising in the search of QT solutions with huge number of layers. Moreover, a general version of the combinatorial algorithm to find QT stacks is proposed in this work. It is also proven that the previous estimation of the number of QT solutions, for a given number of plies and saturatedgroups, is not correct because a larger number of solutions has been found in this study.
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- 2018
30. Du texte antique à la publication scientifique : outils d’analyse numériques des contenus et ponts conceptuels
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Lamé, Marion, Nouvel, Blandine, University of Pisa - Università di Pisa, Centre Camille Jullian - Histoire et archéologie de la Méditerranée et de l'Afrique du Nord de la protohistoire à la fin de l'Antiquité (CCJ), Aix Marseille Université (AMU)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Fédération et Ressources sur l'Antiquité (FRANTIQ), Centre National de la Recherche Scientifique (CNRS), Alliance of Digital Humanities Organizations (ADHO), Université de Pise, and Nouvel, Blandine
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[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
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- 2016
31. La renomination dans les discours de la présidentielle 2012
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Bouzereau, Camille, BCL, équipe Linguistique de l’énonciation, Bases, Corpus, Langage (UMR 7320 - UCA / CNRS) (BCL), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), and Université de Pise
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Nomination ,Énonciation ,Discours politique ,[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,Populisme ,ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
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- 2016
32. Medicinal Plants Used in Mali for the Treatment of Malaria and Liver Diseases
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Sergio Giani, Geneviève Bourdy, Rokia Sanogo, Korotoumou Traoré, Mahamane Haidara, Nunziatina De Tommasi, Alessandra Braca, Université des Sciences, des Techniques et des Technologies de Bamako (USTTB), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), University of Salerno (UNISA), University of Pisa - Università di Pisa, Aide au Développement de la Médecine Traditionnelle (Aidemet ), Institut National de Recherche en Santé Publique [Bamako] (INRSP), Université des sciences, des techniques et des technologies de Bamako (USTTB), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC), Université de Pise, and Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, Bamako
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COCHLOSPERMUM-TINCTORIUM ,Mali, Malaria, Liver diseases, Medicinal plants, Phytomedicines ,Nauclea ,[SDV]Life Sciences [q-bio] ,MITRAGYNA-INERMIS ,AQUEOUS ROOT EXTRACT ,TRADITIONAL MEDICINE ,DIPHENYLMETHYL-SUBSTITUTED XANTHONES ,Plant Science ,Mali ,01 natural sciences ,Argemone mexicana ,Antimalarials ,TRICHILIA-EMETICA ,Medicinal plants ,Drug Discovery ,parasitic diseases ,Combretum micranthum ,medicine ,Humans ,VITRO ANTIMALARIAL ACTIVITY ,TINCTORIUM A. RICH ,Artemisinin ,Liver diseases ,Pharmacology ,Phytomedicines ,ENTADA-AFRICANA ,Combretaceae ,Plants, Medicinal ,biology ,Traditional medicine ,010405 organic chemistry ,Liver Diseases ,General Medicine ,IN-VITRO ,biology.organism_classification ,medicine.disease ,0104 chemical sciences ,3. Good health ,Malaria ,010404 medicinal & biomolecular chemistry ,Complementary and alternative medicine ,Trichilia emetica ,medicine.drug ,Phytotherapy - Abstract
International audience; Today, ethno-pharmacology is a very important resource in order to discover new therapies for the current diseases. Moreover, another good justification for the ethno-pharmacological approach is to obtain new, effective, less expensive and simple therapies, limiting at the same time the cost of pharmaceutical research. Two major anti-malarial drugs widely used today, i.e. quinine and artemisinin, came respectively from Peruvian and Chinese ancestral treatments reported in the traditional medicines. In this contest, there is an urgent need for the discovery of new drugs, due to the critical epidemiological situation of this disease and to the growth of resistances. In Mali, malaria and liver diseases remain one of the leading public health problems. Many medicinal plants are often used, in local traditional medicine, for the treatment at the same time of malaria and liver diseases, including hepatic syndromes, jaundice, hepatitis and other hepatic disorders. Moreover, in the local language Bamanan, the word "Sumaya" is used both for malaria and some liver diseases. In addition, we noted that some of the improved traditional phytomedicines produced by the Department of Traditional Medicine are prescribed by modem doctors both for malaria and liver diseases. In this review, pharmacological, toxicological and phytochemical data on Argemone mexicana L. (Papaveraceae), Cochlospermum tinctorium Pen. ex A. Rich (Cochlospermaceae), Combretum micranthum G.Don (Combretaceae), Entada africana Guillet Pen. (Mimosaceae), Erythrina senegalensis A. DC (Fabaceae), Mitragyna inermis (Willd) Kuntze (Rubiaceae), Nauclea latifolia Smith syn. Sarcocephalus latifolius (Smith) Bruce (Rubiaceae), Securidaca longepedunculata Fresen (Polygalaceae), Trichilia emetica Vahl. (Meliaceae), and Vernonia colorata (Willd) Drake (Asteraceae) are reported. Some of the collected data could be used to improve the actual herbal drugs and to propose new phytomedicines for the management of malaria and liver diseases.
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- 2016
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33. The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype
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Karen, Dawidowicz, Yannick, Allanore, Mickaël, Guedj, Céline, Pierlot, Stefano, Bombardieri, Alejandro, Balsa, René, Westhovens, Pilar, Barrera, Helena, Alves, Vitor Hugo, Teixeira, Elisabeth, Petit-Teixeira, Leo, van de Putte, Piet, van Riel, Bernard, Prum, Thomas, Bardin, Olivier, Meyer, François, Cornélis, Philippe, Dieudé, A, Lopez-Vaz, Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel), Université d'Évry-Val-d'Essonne (UEVE), Service de rhumatologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire Statistique et Génome (SG), Institut National de la Recherche Agronomique (INRA)-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Chimie Organique et Macromoleculaire (UMR CNRS 8009), Université de Lille, Sciences et Technologies-Ecole Nationale Supérieure de Chimie de Lille (ENSCL), Université de Pise, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Nijmegen Medical Centre [Nijmegen], Hospital de São João [Porto], Universidade de Coimbra [Coimbra], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Service de Rhumatologie [CHU Lariboisière], Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Cochin [AP-HP]-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Université Paris Descartes - Paris 5 (UPD5), Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel - EA 3886), Hôpital Lariboisière, Ecole Nationale Supérieure de Chimie de Lille (ENSCL)-Université de Lille, Sciences et Technologies, and University of Pisa - Università di Pisa
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Adult ,Male ,Genotype ,Genetic Linkage ,Immunology ,Single-nucleotide polymorphism ,medicine.disease_cause ,Polymorphism, Single Nucleotide ,Linkage Disequilibrium ,General Biochemistry, Genetics and Molecular Biology ,Autoimmunity ,Arthritis, Rheumatoid ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Rheumatoid Factor ,Humans ,Immunology and Allergy ,Medicine ,SNP ,Rheumatoid factor ,Genetic Predisposition to Disease ,030304 developmental biology ,030203 arthritis & rheumatology ,Genetics ,0303 health sciences ,business.industry ,Haplotype ,Phenotype ,Haplotypes ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Interferon Regulatory Factors ,Evaluation of complex medical interventions Auto-immunity, transplantation and immunotherapy [NCEBP 2] ,Female ,business ,IRF5 ,Interferon regulatory factors - Abstract
Contains fulltext : 96445.pdf (Publisher’s version ) (Closed access) BACKGROUND: Increased expression of type I IFN genes, also referred to as an IFN signature, has been detected in various autoimmune diseases including rheumatoid arthritis (RA). Interferon regulatory factors, such as IRF5, coordinate type I IFN expression. Multiple IRF5 variants were suggested as autoimmunity susceptibility factors. OBJECTIVE: As the linkage proof remains important to establish fully any genetic RA susceptibility factor, the authors took advantage of the largest reported European trio family resource dedicated to RA to test for linkage IRF5 and performed a genotype-phenotype analysis. METHODS: 1140 European Caucasian individuals from 380 RA trio families were genotyped for IRF5 rs3757385, rs2004640 and rs10954213 single nucleotide polymorphisms (SNP). RESULTS: Single marker analysis provided linkage evidence for each IRF5 SNP investigated. IRF5 linked to RA with two haplotypes: the CTA risk haplotype 'R' (transmission (T)=60.6%, p=23.1x10(-5)) and the AGG protective haplotype 'P' (T=39.6%, p=0.0015). Linkage was significantly stronger in non-erosive disease for both IRF5 R and P haplotypes (T=73.9%, p=4.20x10(-5) and T=19.6%, p=3.66x10(-5), respectively). Multivariate logistic regression analysis found IRF5 linked to RA independently of the rheumatoid factor status. IRF5 RR and PP haplotypic genotypes were associated with RA, restricted to the non-erosive phenotype: p=1.68x10(-4), OR 4.80, 95% CI 2.06 to 11.19; p=0.003, OR 0.17, 95% CI 0.05 to 0.57, respectively. CONCLUSION: This study provides the 'association and linkage proof' establishing IRF5 as a RA susceptibility gene and the identification of a genetic factor that seems to contribute to the modulation of the erosive phenotype. Further studies are warranted to clarify the role of IRF5 in RA and its subphenotypes.
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- 2011
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34. Pyroclastic flow hazard assessment at Somma–Vesuvius based on the geological record
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W. Luperini, Roberto Santacroce, Roberto Sulpizio, Alessandro Sbrana, Daniele Andronico, Raffaello Cioni, Lucia Gurioli, Laboratoire Magmas et Volcans (LMV), Observatoire de Physique du Globe de Clermont-Ferrand (OPGC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), CIRISIVU Dpto Geomineralogico, Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Dipartimento di Scienze della Terra [Pisa], University of Pisa - Università di Pisa, Dipartimento di Scienze della Terra, Università degli Studi di Firenze = University of Florence (UniFI), Institut national des sciences de l'Univers (INSU - CNRS)-Université Jean Monnet [Saint-Étienne] (UJM)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Observatoire de Physique du Globe de Clermont-Ferrand (OPGC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Bari Aldo Moro (UNIBA), Université de Pise, and Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI)
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010504 meteorology & atmospheric sciences ,[SDE.MCG]Environmental Sciences/Global Changes ,Pyroclastic flow ,Geochemistry ,Pyroclastic rock ,010502 geochemistry & geophysics ,01 natural sciences ,Geochemistry and Petrology ,Pumice ,[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/Volcanology ,Caldera ,Geomorphology ,ComputingMilieux_MISCELLANEOUS ,0105 earth and related environmental sciences ,geography ,geography.geographical_feature_category ,Facies ,Mt Somma ,Volcanic rock ,Igneous rock ,13. Climate action ,Magma ,Hazard assessment ,Pyroclastic density currents ,Isopach map ,Geology - Abstract
During the past 22 ka of activity at Somma–Vesuvius, catastrophic pyroclastic density currents (PDCs) have been generated repeatedly. Examples are those that destroyed the towns of Pompeii and Ercolano in AD 79, as well as Torre del Greco and several circum-Vesuvian villages in AD 1631. Using new field data and data available from the literature, we delineate the area impacted by PDCs at Somma–Vesuvius to improve the related hazard assessment. We mainly focus on the dispersal, thickness, and extent of the PDC deposits generated during seven plinian and sub-plinian eruptions, namely, the Pomici di Base, Greenish Pumice, Pomici di Mercato, Pomici di Avellino, Pompeii Pumice, AD 472 Pollena, and AD 1631 eruptions. We present maps of the total thickness of the PDC deposits for each eruption. Five out of seven eruptions dispersed PDCs radially, sometimes showing a preferred direction controlled by the position of the vent and the paleotopography. Only the PDCs from AD 1631 eruption were influenced by the presence of the Mt Somma caldera wall which stopped their advance in a northerly direction. Most PDC deposits are located downslope of the pronounced break-in slope that marks the base of the Somma–Vesuvius cone. PDCs from the Pomici di Avellino and Pompeii Pumice eruptions have the most dispersed deposits (extending more than 20 km from the inferred vent). These deposits are relatively thin, normally graded, and stratified. In contrast, thick, massive, lithic-rich deposits are only dispersed within 7 to 8 km of the vent. Isopach maps and the deposit features reveal that PDC dispersal was strongly controlled by the intensity of the eruption (in terms of magma discharge rate), the position of the vent area with respect to the Mt Somma caldera wall, and the pre-existing topography. Facies characteristics of the PDC deposits appear to correlate with dispersal; the stratified facies are consistently dispersed more widely than the massive facies.
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- 2010
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35. The Late Holocene to Pleistocene tephrostratigraphic record of Lake Ohrid (Albania)
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Giuseppe Siani, Benoit Caron, Roberto Santacroce, Giovanni Zanchetta, Roberto Sulpizio, Interactions et dynamique des environnements de surface (IDES), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, CIRISIVU Dpto Geomineralogico, Università degli studi di Bari Aldo Moro (UNIBA), Dipartimento di Scienze della Terra [Pisa], University of Pisa - Università di Pisa, Institut des Sciences de la Terre de Paris (iSTeP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), and Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA)
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Italian volcanoes ,Lake Ohrid ,010504 meteorology & atmospheric sciences ,Pleistocene ,Balkans ,010502 geochemistry & geophysics ,01 natural sciences ,Paleontology ,Tephra ,Geomorphology ,tephrochronology ,ComputingMilieux_MISCELLANEOUS ,Holocene ,0105 earth and related environmental sciences ,Global and Planetary Change ,geography ,geography.geographical_feature_category ,Explosive eruption ,Stratigraphy ,Volcano ,[SDU]Sciences of the Universe [physics] ,Albania ,General Earth and Planetary Sciences ,Tephrochronology ,Geology ,tephrostratigraphy ,Chronology - Abstract
International audience; We present in this work a tephrostratigraphic record from a sediment piston core (JO 2004) from Lake Ohrid. Five tephra layers were recognised, all from explosive eruptions of southern Italy volcanoes. A multidisciplinary study was carried out, including stratigraphy, AMS 14C chronology and geochemistry. The five tephra layers were correlated with terrestrial proximal counterparts and with both marine and lacustrine tephra layers already known in the central Mediterranean area. The oldest is from Pantelleria Island (P11, 131 ka BP). Other three tephra layers are from Campanian volcanoes: X6, Campanian Ignimbrite-Y5 and SMP1-Y3 (107, 39 and 31 ka BP respectively). The youngest tephra layer corresponds to the FL eruption from Etna Volcano (3.4 ka BP). In three cases these recognitions confirm previous findings in the Balkans, while two of them were for the first time recognised in the area, with a significant enlargement of the previous assessed dispersal areas.
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- 2010
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36. Replication of the tumor necrosis factor receptor−associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a European family-based study
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Ivo Gut, Pilar Barrera, A. Lopes-Vaz, Thomas Bardin, Rene Westhovens, Vitor H. Teixeira, Helena Alves, Jeanine J. Houwing-Duistermaat, René E. M. Toes, S. Vrijmoet, Laëtitia Michou, P.L.C.M. van Riel, Twj Huizinga, Dora Pascual-Salcedo, Alejandro Balsa, Stefano Bombardieri, François Cornélis, Bernard Prum, Maria J.G. Fernandes, Trdj Radstake, L. B. A. Van De Putte, Carlos Vaz, Elisabeth Petit-Teixeira, Paola Migliorini, Dominique Rocha, Fina A S Kurreeman, Universiteit Leiden, Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel), Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay, University of Pisa - Università di Pisa, Hospital Universitario La Paz, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Nijmegen Medical Centre [Nijmegen], Hospital de São João [Porto], Center for Research in Ceramic and Composite Materials (CICECO), Universidade de Aveiro, Université d'Évry-Val-d'Essonne (UEVE), Radboud University [Nijmegen], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Service de Rhumatologie [CHU Lariboisière], Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Center of Occupational Medicine, National Institute of Public Health, Centre National de Génotypage (CNG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Department of rheumatology, Leiden University Medical Center (LUMC), Universiteit Leiden-Universiteit Leiden, Universiteit Leiden [Leiden], Université de Pise, and Radboud university [Nijmegen]
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Male ,Candidate gene ,Genotype ,Immunology ,Population ,Locus (genetics) ,Population stratification ,Auto-immunity, transplantation and immunotherapy [N4i 4] ,White People ,Arthritis, Rheumatoid ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Humans ,Immunology and Allergy ,Medicine ,Family ,Genetic Predisposition to Disease ,Pharmacology (medical) ,Rheumatoid arthritis ,Allele ,10. No inequality ,education ,Allele frequency ,Alleles ,Genetic Association Studies ,030304 developmental biology ,Genetic association ,Chronic inflammation and autoimmunity [UMCN 4.2] ,030203 arthritis & rheumatology ,Genetics ,0303 health sciences ,education.field_of_study ,Polymorphism, Genetic ,business.industry ,Effective Hospital Care [EBP 2] ,Complement C5 ,Odds ratio ,TNF Receptor-Associated Factor 1 ,Pathogenesis and modulation of inflammation [N4i 1] ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Evaluation of complex medical interventions [NCEBP 2] ,Case-Control Studies ,Female ,business ,Infection and autoimmunity [NCMLS 1] - Abstract
Contains fulltext : 71178.pdf (Publisher’s version ) (Closed access) OBJECTIVE: We recently showed, using a candidate gene approach in a case-control association study, that a 65-kb block encompassing tumor necrosis factor receptor-associated factor 1 (TRAF1) and C5 is strongly associated with rheumatoid arthritis (RA). Compared with case-control association studies, family-based studies have the added advantage of controlling potential differences in population structure and are not likely to be hampered by variation in population allele frequencies, as is seen for many genetic polymorphisms, including the TRAF1/C5 locus. The aim of this study was to confirm this association in populations of European origin by using a family-based approach. METHODS: A total of 1,356 western European white individuals from 452 "trio" families were genotyped for the rs10818488 polymorphism, using the TaqMan allelic discrimination assay. RESULTS: We observed evidence for association, demonstrating departure from Mendel's law, with an overtransmission of the rs10818488 A allele (A = 55%; P = 0.036). By taking into consideration parental phenotypes, we also observed an increased A allele frequency in affected versus unaffected parents (A = 64%; combined P = 0.015). Individuals carrying the A allele had a 1.2-fold increased risk of developing RA (allelic odds ratio 1.24, 95% confidence interval 1.04-1.50). CONCLUSION: Using a family-based study that is robust against population stratification, we provide evidence for the association of the TRAF1/C5 rs10818488 A allele and RA in populations of European descent, further substantiating our previous findings. Future functional studies should yield insight into the biologic relevance of this locus to the pathways involved in RA.
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- 2008
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37. De la sociologie à l’anthropologie juridique: Les études de Louis Gernet sur le droit grec ancien
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Taddei, Andrea and Université de Pise
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Louis Gernet ,anthropology of law ,legal sociology ,sociologie juridique ,prédroit ,anthropologie juridique ,[SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnology ,classics ,[SHS.HIST]Humanities and Social Sciences/History ,[SHS.CLASS]Humanities and Social Sciences/Classical studies ,sciences de l'Antiquité - Abstract
International audience; Based on the analysis of the intellectual work of Louis Gernet, this article aims to focus on the relationships between the fields of classics, sociology of law and legal anthropology, since the middle of the twentieth century until today. It is worth placing Gernet’s studies on Ancient Greek Law within the framework of a wider and larger research project on Ancient Greek Civilization, that we are able to restore starting from a work on his unpublished papers. More precisely, the patterning and use of the idea of “prédroit” in the field of sociology of law and contemporary legal anthropology can help both to retrace a dialogue among different disciplines, and to consider how the idea of “prédroit” provides a useful hermeneutical tool for understanding not only specific elements of Ancient Greek law, but also – more broadly – several aspects of ancient Greek civilization.; L’œuvre intellectuelle de Louis Gernet est ici analysée pour construire une réflexion autour des relations entre sciences de l’antiquité, sociologie juridique et anthropologie juridique des années 1950 jusqu’à nos jours. Il s’agit de placer les études de Gernet sur le droit grec ancien à l’intérieur de son projet plus général d’enquête sur la société grecque, que les documents inédits nous permettent de reconstruire avec précision. Plus particulièrement, le façonnement et l’utilisation de la notion de « prédroit » dans les domaines de la sociologie juridique et de l’anthropologie juridique contemporaine nous permettent d’observer plusieurs formes de dialogue entre différentes disciplines et de clarifier la fonction que la notion de « prédroit » peut continuer à exercer, comme outil épistémologique, pour la compréhension de la société grecque antique.
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- 2016
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38. Relationship between SNPs and Expression Level for Candidate Genes in Rheumatoid Arthritis
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Fodil, M., Teixeira, V. H., Chaudru, V., Hilliquin, P., Bombardieri, S., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Migliorin, P., Bardin, T., Cornelis, F., Boudjema, A., Petit-Teixeira, Elisabeth, Migliorini, P., Dequeker, J., Pascuale-Salcedo, D., Van De Putte, L., Van Riel, P., Radstake, T. R., Lopes-Vaz, A., Fernandes, M., Vaz, C., Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel), Université d'Évry-Val-d'Essonne (UEVE), Université des sciences et de la Technologie d'Oran Mohamed Boudiaf [Oran] (USTO MB), University College de Londres [U.K.] (UCL - U.K.), Centre Hospitalier Sud Francilien, CH Evry-Corbeil, Université de Pise, Service de Rhumatologie [CHU Lariboisière], Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), La Paz Hospital, IdiPAZ, Center for Research in Ceramic and Composite Materials (CICECO), Universidade de Aveiro, and University of Pisa - Università di Pisa
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Adult ,Genetic Markers ,Male ,Candidate gene ,Genotype ,Population ,Immunology ,Lymphocyte Antigen 96 ,Single-nucleotide polymorphism ,Genome-wide association study ,Eosinophil-Derived Neurotoxin ,Biology ,Polymorphism, Single Nucleotide ,Arthritis, Rheumatoid ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Rheumatology ,Immunology and Allergy ,Humans ,Calgranulin A ,Genetic Predisposition to Disease ,education ,030304 developmental biology ,Genetic association ,030203 arthritis & rheumatology ,Genetics ,Medicine(all) ,0303 health sciences ,education.field_of_study ,General Medicine ,Middle Aged ,3. Good health ,Interleukin-2 Receptor beta Subunit ,Core Binding Factor Alpha 3 Subunit ,IL2RB ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Genetic marker ,Inflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5] ,Cytokines ,Female ,Transcriptome - Abstract
International audience; Objectives: The study of polymorphisms of genes differentially expressed may lead to the identification of putative causal genetic variants in multifactorial diseases such as rheumatoid arthritis (RA). Based on preceding transcriptomic results, we genotyped 10 single nucleotide polymorphisms (SNPs) belonging to six genes (S100A8, RNASE2, PGLYRP1, RUNX3, IL2RB, and LY96) showing the highest fold change (\backslashtextgreater 1.9) when level of expression was compared between RA patients and controls. These SNPs were then analysed to evaluate their role in RA. Method: The relationship between gene expression and genotypes of SNPs was first investigated by Kruskal-Wallis and Mann-Whitney tests in RA patients and controls. The genetic association of these SNPs with RA were then analysed using family-based association tests in trio families. Results: We found that RNASE2 gene expression was related to rs2013109 genotypes in 14 RA patients (p = 0.030). The association study in a discovery sample of 200 French trio families revealed a significant association with RA for one SNP, PGLYRP1-rs2041992 (p = 0.019); this association was stronger in trios where RA patients carried the HLA-DRB1 shared epitope (SE) (p = 0.003). However, this association was not found in a replication sample of 240 European trio families (p = 0.6). Conclusions: Family-based association tests did not reveal an association between RA and any SNP of the candidate genes tested. However, RNASE2 gene expression was differentially expressed in RA patients considering a sequence polymorphism. This result led us to highlight the potential disease-specific regulation for this candidate gene in RA. © 2015 Informa Healthcare on license from Scandinavian Rheumatology Research Foundation.
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- 2015
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39. La programmation du développement régional. Des velléités à l'utopie réaliste : le cas de la Toscane
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Nicola Bellini, Emmanuel Négrier, Giuliano Bianchi, Université de Sienne, Université de Pise, Centre d'Etudes Politiques de l'Europe Latine (CEPEL), and Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)
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General Medicine ,16. Peace & justice ,[SHS.SCIPO]Humanities and Social Sciences/Political science ,[SHS]Humanities and Social Sciences - Abstract
Bianchi Giuliano, Bellini Nicola, Négrier Emmanuel. La programmation du développement régional. Des velléités à l'utopie réaliste : le cas de la Toscane. In: Pôle Sud, n°8, 1998. Elections et politiques régionales, sous la direction de Emmanuel Négrier . pp. 98-113.
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- 1998
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40. Cellular Adhesion Gene SELP Is Associated with Rheumatoid Arthritis and Displays Differential Allelic Expression
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Burkhardt, J., Blume, M., Petit-Teixeira, E., Teixeira, V.H., Steiner, A., Quente, E., Wolfram, G., Scholz, M., Pierlot, C., Migliorini, P., Bombardieri, S., Balsa, A., Westhovens, R., Barrera, P., Radstake, T.R.D.J., Alves, H., Bardin, T., Prum, B., Emmrich, F., Cornelis, F., Ahnert, P., Kirsten, H., Translational Centre for Regenerative Medicine (TRM), Department of Cell Therapy, Universität Leipzig [Leipzig]-Universität Leipzig [Leipzig], Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel - EA 3886), Université d'Évry-Val-d'Essonne (UEVE), Institute for Medical Informatics, University Hospital La Paz, Madrid, Unité de Génétique Clinique Adulte, Hôpital Lariboisière, Laboratoire Statistique et Génome (SG), Institut National de la Recherche Agronomique (INRA)-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Universität Leipzig [Leipzig], Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel), University College of London [London] (UCL), Université de Pise, Technologie campus Gent - KU Leuven (KU Leuven), Radboud university [Nijmegen], University Medical Center [Utrecht], Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Publica, Universität Leipzig, Université d\\\'Evry-Val d\\\'Essonne, University College London, Fraunhofer-Institut für Zelltherapie und Immunologie, Pisa University, La Paz Hospital, KU Leuven, Nijmegen University, University Medical Center, Porto San Joao Hospital, Universität Leipzig-Universität Leipzig, University of Pisa - Università di Pisa, and Radboud University [Nijmegen]
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Male ,LINKAGE DISEQUILIBRIUM ,Epidemiology ,Gene Expression ,lcsh:Medicine ,SOLUBLE P-SELECTIN ,GENOME-WIDE ASSOCIATION ,MULTIPLE-SCLEROSIS ,MYOCARDIAL-INFARCTION ,PTPN11 MUTATIONS ,RISK ,MOLECULES ,DISEASES ,EVENTS ,Arthritis, Rheumatoid ,Rheumatoid ,Databases, Genetic ,Medicine and Health Sciences ,Displays Differential Allelic Expression ,Age of Onset ,lcsh:Science ,Single Nucleotide ,P-Selectin ,Genetic Epidemiology ,Female ,Research Article ,Protein Binding ,Adult ,Genotype ,Immunology ,Quantitative Trait Loci ,Rheumatoid Arthritis ,Polymorphism, Single Nucleotide ,Gene SELP ,Autoimmune Diseases ,Molecular Genetics ,Young Adult ,Databases ,Rheumatology ,Genetic ,Adhesion molecules, cell migration, genotyping, transcription factors, rheumatoid arthritis ,Genetics ,Cell Adhesion ,Humans ,Gene Regulation ,ddc:610 ,Polymorphism ,Alleles ,Genetic Association Studies ,Evolutionary Biology ,Binding Sites ,Arthritis ,lcsh:R ,Biology and Life Sciences ,Computational Biology ,Human Genetics ,Gene Expression Regulation ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Genetics of Disease ,Inflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5] ,Genetic Polymorphism ,Clinical Immunology ,lcsh:Q ,Adhäsionsmoleküle, Genotypisierung, Zelltranskription, Zellwanderung, Gelenkrheumatismus ,Population Genetics ,Transcription Factors - Abstract
In rheumatoid arthritis (RA), a key event is infiltration of inflammatory immune cells into the synovial lining, possibly aggravated by dysregulation of cellular adhesion molecules. Therefore, single nucleotide polymorphisms of 14 genes involved in cellular adhesion processes (CAST, ITGA4, ITGB1, ITGB2, PECAM1, PTEN, PTPN11, PTPRC, PXN, SELE, SELP, SRC, TYK2, and VCAM1) were analyzed for association with RA. Association analysis was performed consecutively in three European RA family sample groups (Nfamilies = 407). Additionally, we investigated differential allelic expression, a possible functional consequence of genetic variants. SELP (selectin P, CD62P) SNP-allele rs6136-T was associated with risk for RA in two RA family sample groups as well as in global analysis of all three groups (ptotal = 0.003). This allele was also expressed preferentially (p
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- 2014
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41. HLA Shared Epitope and ACPA: Just a Marker or an Active Player?
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Paola Migliorini, John Sidney, Laëtitia Michou, Elisabeth Petit Teixeira, Ilaria Puxeddu, Alessandro Sette, François Cornelis, Federico Pratesi, Université de Pise, Laboratoire de recherche européen pour la polyarthrite rhumatoïde (GenHotel), Université d'Évry-Val-d'Essonne (UEVE), Laboratory of Epidemiology, Clinical Epidemiology Unit, Istituto Superiore di Sanita [Rome], La Jolla Institute for Immunology [La Jolla, CA, États-Unis], University of Pisa - Università di Pisa, and Istituto Superiore di Sanità (ISS)
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musculoskeletal diseases ,Immunology ,Antigen presentation ,Arthritis ,Human leukocyte antigen ,Biology ,Epitope ,Antibodies ,Arthritis, Rheumatoid ,03 medical and health sciences ,Epitopes ,0302 clinical medicine ,Immune system ,Antigen ,immune system diseases ,Rheumatoid ,medicine ,Immunology and Allergy ,Humans ,Animals ,Allele ,skin and connective tissue diseases ,Autoantibodies ,030203 arthritis & rheumatology ,Genetics ,Antigen Presentation ,Proteins ,HLA-DR Antigens ,medicine.disease ,Antibodies, Anti-Idiotypic ,Anti-Idiotypic ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,biology.protein ,Citrulline ,Antibody ,030217 neurology & neurosurgery ,HLA-DRB1 Chains - Abstract
International audience; Autoantibody production is genetically controlled and anti-citrullinated protein/peptide antibodies (ACPA) are not an exception to the rule. ACPA are highly specific markers of rheumatoid arthritis (RA) and are also associated with a more severe disease course. The production of ACPA is almost invariably observed in HLA-shared epitope (SE) positive patients. The DRB1 alleles sharing SE are those conferring susceptibility to RA. SE alleles behave like immune response genes, controlling both the specificity and the amount of ACPA produced. These data suggest a role of SE in the presentation of citrullinated antigens. The ability of SE alleles to bind selectively to citrullinated sequences as compared to the native counterparts has been demonstrated in the case of peptides derived from several joint associated proteins (vimentin, fibrinogen and cartilage intermediate-layer protein). On the contrary, EBV-derived citrullinated peptides do not display a biologically relevant binding to SE alleles even if the immune response to VCPs is under the genetic control of these alleles (namely *0401 and *0404). Thus, the presentation of citrullinated epitopes does not represent the only molecular mechanisms underlying the HLA-DRB1 effect on ACPA production.
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- 2013
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42. Investigation of the elastic behavior of reciprocal systems using homogenization techniques
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Greco, Lorenzo, Lebée, Arthur, Douthe, Cyril, Université de Pise, Matériaux et Structures Architecturés (msa), Laboratoire Navier (navier umr 8205), Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-École des Ponts ParisTech (ENPC)-Centre National de la Recherche Scientifique (CNRS)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-École des Ponts ParisTech (ENPC)-Centre National de la Recherche Scientifique (CNRS), Expérimentation et Modélisation des Matériaux et des Structures (IFSTTAR/MAST/EMMS), Communauté Université Paris-Est-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR), and Cadic, Ifsttar
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[PHYS.MECA.STRU] Physics [physics]/Mechanics [physics]/Structural mechanics [physics.class-ph] ,[PHYS.MECA.STRU]Physics [physics]/Mechanics [physics]/Mechanics of the structures [physics.class-ph] ,[SPI.MECA.STRU] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Structural mechanics [physics.class-ph] ,ELASTICITE ,PLAQUE ,HOMOGENEISATION ,[SPI.MECA.STRU]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Mechanics of the structures [physics.class-ph] - Abstract
International audience; In this paper, the authors endeavour to develop design formulas for reciprocal systems using homogenization techniques. The theoretical background for homogenizing periodic beams systems as Kirchhoff-Love plates is first recalled. Then it is applied to a square reciprocal system. It is found that only biaxial bending (i.e. positive Gaussian curvature) generates stress inside the beams so that the equivalent plate model is a degenerated Kirchhoff-Love which is fully detailed. Then, some optimal configurations are investigated in terms of bending stiffness and strength. Finally, in order to validate the approach, full finite element simulations of simply supported reciprocal systems on square boundaries are compared with the homogenized solution previously derived. The convergence of the model and its accuracy for reasonable scale ratio is confirmed. Nexorade, Homogenization, Periodic plates, Space frame
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- 2013
43. Stendhal, Journaux et papiers, tome 1, 1797-1804
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Meynard, Cécile, de Jacquelot, Hélène, Corredor, Marie-Rose, Équipe de recherches sur l'histoire, les théories et la didactique de la littérature et des arts du spectacle des 19e, 20e et 21e siècles (Traverses 19-21), Université Stendhal - Grenoble 3, Université de Pise, and Univ Angers, Okina
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[SHS.LITT] Humanities and Social Sciences/Literature ,[SHS.LITT]Humanities and Social Sciences/Literature - Abstract
Ce premier tome des Journaux et Papiers de Stendhal (sur quatre prévus) correspond à la période de sa première formation intellectuelle (1797-1804). Les documents présentés ici se répartissent en trois grandes périodes qui correspondent à des déplacements et à des séjours prolongés dans des lieux définis: de Grenoble à Paris via l'Italie (1797-1802), Paris (avril 1802-juin 1803) et Grenoble et Claix (juin 1803-mars 1804). Les trois ensembles documentaires ainsi constitués témoignent de l'évolution de Stendhal, de l'adolescent grenoblois puis tout jeune militaire en Italie à l'apprenti écrivain qui tâtonne entre plusieurs domaines littéraires. Le principe gouvernant le travail des éditrices a été de fournir une édition fidèle à l’état des manuscrits, qui respecte l’intégrité des documents même si l’ordre chronologique ou thématique ne semble pas évident au premier regard. Une introduction générale et une Note sur le texte exposent les grandes lignes qui sous-tendent cette nouvelle édition des Journaux et Papiers de Stendhal. Un apparat critique important en fin de volume (notices et notes) accompagne le lecteur, qui, notamment, ne retrouvera pas le découpage traditionnel entre intime, littéraire et théâtre. Cette édition donne ainsi accès à la table de travail du futur écrivain, où se côtoient journaux, cahiers de pensées et de projets littéraires ainsi que papiers divers. En annexe figurent les notes et synthèses – jusqu’ici inédites - rédigées par le tout jeune homme dans le cadre des cours de Dubois Fontanelle à l’École centrale de l’Isère entre 1797 et 1798. Ces documents sont regroupés dans un dossier qui a été constitué par Hélène Spengler, Hélène de Jacquelot, Cécile Meynard et Jean-Jacques Labia.
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- 2013
44. Pour une heuristique de la traduction automatique basée sur la traduction pédagogique. Session 6 - Didactique, enseignement, apprentissage
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Barone, Charles, Franzelli, Valeria, ORANGE, Colette, and Université de Pise
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[INFO.INFO-CL] Computer Science [cs]/Computation and Language [cs.CL] ,[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,Tralogy II ,[SHS.LANGUE] Humanities and Social Sciences/Linguistics ,[INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL] - Abstract
International audience; Nous présentons ici une recherche centrée sur la traduction du français vers l'italien dont l'objectif est double : il s'agit, d'une part, de tester l'hypothèse que l'apprentissage d'un système de traduction automatique peut se faire de manière progressive, selon des modalités comparables à celles de l'ap-prentissage humain d'une langue étrangère, d'autre part de comparer les erreurs produites par des étudiants au cours d'activités de traduction péda-gogique avec les erreurs relevables en traduction automatique, afin de ju-ger si l'identification des problèmes de la traduction humaine peuvent contribuer à une amélioration des résultats de la traduction automatique.
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- 2013
45. Assessing the potential of farming regions to fulfill agro-environmental functions: A case study in Tuscany (Italy)
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Elisa Marraccini, Hélène Rapey, Mariassunta Galli, Sylvie Lardon, Enrico Bonari, Irstea Publications, Migration, Mutations des activités des espaces et des formes d'organisation dans les territoires ruraux (UMR METAFORT), Institut National de la Recherche Agronomique (INRA)-AgroParisTech-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Istituto di Scienze della Vita, Scuola Universitaria Superiore Sant'Anna [Pisa] (SSSUP), Scuola Superiore Sant'Anna (Pisa, Italy), Irstea of Clermont-Ferrand (France), Mutations des activités des espaces et des formes d'organisation dans les territoires ruraux (METAFORT), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut National de la Recherche Agronomique (INRA)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-AgroParisTech, Scuola Superiore Sant'Anna [Pisa], University of Pisa - Università di Pisa, Mutations des activités des espaces et des formes d'organisation dans les territoires ruraux ( METAFORT ), AgroParisTech-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique ( INRA ) -VetAgro Sup ( VAS ) -Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture ( IRSTEA ), AgroParisTech-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Institut National de la Recherche Agronomique (INRA)-AgroParisTech-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, and Université de Pise
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[SDV.SA]Life Sciences [q-bio]/Agricultural sciences ,[SDE] Environmental Sciences ,Conservation of Natural Resources ,010504 meteorology & atmospheric sciences ,Forest management ,Land cover ,01 natural sciences ,GEOGRAPHICAL CLUSTERING ,Environmental protection ,[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciences ,0105 earth and related environmental sciences ,2. Zero hunger ,Spatial Analysis ,Global and Planetary Change ,Geography ,Ecology ,business.industry ,Environmental resource management ,LANDSCAPE DIVERSITY ,SOIL CONSERVATION ,Agriculture ,WATER QUALITY ,04 agricultural and veterinary sciences ,Models, Theoretical ,15. Life on land ,Pollution ,Variable (computer science) ,Italy ,Geographical cluster ,[SDE]Environmental Sciences ,LAND COVER ,Geographic Information Systems ,040103 agronomy & agriculture ,Spatial ecology ,0401 agriculture, forestry, and fisheries ,Spatial variability ,business ,Soil conservation - Abstract
[Departement_IRSTEA]Territoires [TR1_IRSTEA]DTAM [Axe_IRSTEA]DTAM1-REPRO; International audience; The increasing interest in agro-environmental management entails having tools to assess, monitor and map agro-environmental functions in different regional contexts. In Europe, decision-making in agro-environmental policies generally targets single functions instead of multiple ones and rarely considers the regional variability of agricultural or geo-physical conditions that may influence the fulfillment of functions. We propose and test a method to assess the potential of farming regions to fulfill a set of agro-environmental functions. The method was applied in the “Collina interna grossetana” farming region (Italy) and concerned three functions: protection of surface water from nitrates, protection of soil from erosion, and conservation of landscape diversity. These functions were qualified and mapped using various geo-physical and agricultural land cover descriptors from common geographical datasets. All of the descriptors were combined using geographical cluster analysis to identify their contribution to the three functions and thus to assess the potential of the farming region to fulfill these functions. Three levels of potential were calculated, according to the more or less favorable fulfillment of soil and water functions. No totally favorable contribution to the functions was identified in the studied area. Moreover, we mapped the spatial patterns obtained for the different levels of potential. The landscape diversity function was found to be the least variable in the study area, while different patterns were identified for the other functions. In fact, the northern and central sections of the study region were organized more in the form of large core areas of different levels of potential, whereas the southern section presented more boundary areas, small core areas and isolated pixels. The method may help to establish local priorities in agro-environmental management pointing out where the set of functions is completely or partially fulfilled, as well as where and how it is more or less necessary to focus support measures afforded by environmental policies. Such information could help to palliate the current poor consideration of the spatial variability of functions in local policies.
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- 2013
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46. Les journaux d'écrivains : enjeux génériques et éditoriaux
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Meynard, Cécile, de Jacquelot, Helène, Centre Interdisciplinaire de Recherche sur les Patrimoines en Lettres et Langues (CIRPALL), Université d'Angers (UA), Université de Pise, and Univ Angers, Okina
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[SHS.LITT] Humanities and Social Sciences/Literature ,[SHS.LITT]Humanities and Social Sciences/Literature - Abstract
Les journaux d’écrivains représentent des cas de journaux personnels particuliers par le statut même des diaristes qui les ont écrits. Etudier ces journaux d’écrivains pose plusieurs questions : tenir un journal ou pas ? Pour qui et pour quoi tenir un journal ? Les diaristes eux-mêmes, par leur pratique et leurs interrogations, soulignent combien le journal d’écrivain relève d’une catégorie générique littéraire propre. Dans la relation complexe entre diaristes et destinataires se redéfinissent tout à la fois la notion de l’intimité et la fonction d’un journal d’écrivain. Se pose enfin une question non moins complexe, qui se joue entre diaristes et éditeurs : comment publier un journal d’écrivain sans en trahir la teneur et la signification ?Cet ouvrage, qui rassemble des textes de chercheurs de plusieurs pays portant sur des journaux d’écrivains français et étrangers, du XVIII e au XX e siècle, permet ainsi de faire l’état des lieux de la critique actuelle sur le sujet.
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- 2012
47. Tephrostratigraphy, chronology and climatic events of the Mediterranean basin during the Holocene : an overview
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Zanchetta, G., Sulpizio, R., Roberts, N., Cioni, R., Siani, G., Benoît Caron, Paterne, M., Santacroce, R., University of Pisa - Università di Pisa, CIRISIVU Dpto Geomineralogico, Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Magnetic Resonance and Image Analysis Research Centre (MARIARC), University of Liverpool, Dipartimento di Scienze della Terra [Pisa], Interactions et dynamique des environnements de surface (IDES), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Géochrononologie Traceurs Archéométrie (GEOTRAC), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université de Pise, Università degli studi di Bari Aldo Moro (UNIBA), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), and CRINON, Evelyne
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[SDU.STU] Sciences of the Universe [physics]/Earth Sciences ,[SDU.STU]Sciences of the Universe [physics]/Earth Sciences ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2011
48. The Holocene tephrostratigraphic record of Lake Shkodra (Albania and Montenegro)
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Benoit Caron, Roberto Sulpizio, Aurelien van Welden, Giovanni Zanchetta, Dipartimento di Scienze della Terra [Pisa], University of Pisa - Università di Pisa, Département des sciences de la Terre, Université Paris-Sud - Paris 11 (UP11), Institut des Sciences de la Terre de Paris (iSTeP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), CIRISIVU Dpto Geomineralogico, Università degli studi di Bari, Laboratoire de Géodynamique des Chaines Alpines (LGCA), Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut des Sciences de la Terre (ISTerre), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-PRES Université de Grenoble-Institut de recherche pour le développement [IRD] : UR219-Institut national des sciences de l'Univers (INSU - CNRS)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-PRES Université de Grenoble-Institut de recherche pour le développement [IRD] : UR219-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR), Université de Pisa, Dpt des Sciences de la Terre, Interactions et dynamique des environnements de surface (IDES), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), NATO Science for Peace project (SFP 977 993) INGV-DPC 2005-2007 projects (V-3 subproject on explosive activity of Somma-Vesuvius), Università degli studi di Bari Aldo Moro (UNIBA), Dipartimento di Scienze della Terra, Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, and Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA)
- Subjects
Volcanic hazards ,Italian volcanoes ,010504 meteorology & atmospheric sciences ,Geochemistry ,Trachyte ,[SDU.STU]Sciences of the Universe [physics]/Earth Sciences ,010502 geochemistry & geophysics ,01 natural sciences ,Arts and Humanities (miscellaneous) ,Earth and Planetary Sciences (miscellaneous) ,Tephra ,Geomorphology ,Holocene ,tephrochronology ,ComputingMilieux_MISCELLANEOUS ,0105 earth and related environmental sciences ,Shore ,geography ,Explosive eruption ,geography.geographical_feature_category ,Paleontology ,Montenegro ,Volcano ,13. Climate action ,[SDU]Sciences of the Universe [physics] ,Lake Shkodra ,Albania ,Tephrochronology ,Geology ,[SDU.STU.MI]Sciences of the Universe [physics]/Earth Sciences/Mineralogy ,tephrostratigraphy - Abstract
Two cores were recovered in the southeastern part of Lake Shkodra (Montenegro and Albania) and sampled for identification of tephra layers. The first core (SK13, 7.8 m long) was recovered from a water depth of 7 m, while the second core (SK19, 5.8 m long) was recovered close to the present- day shoreline (water depth of 2 m). Magnetic susceptibility investigations show generally low values with some peaks that in some cases are related to tephra layers. Naked-eye inspection of the cores allowed the identification of four tephra layers in core SK13 and five tephra layers in core SK19. Major element analyses on glass shards and mineral phases allowed correlation of the tephra layers between the two cores, and their attribution to six different Holocene explosive eruptions of southern Italy volcanoes. Two tephra layers have under-saturated composition of glass shards (foiditic and phono- litic) and were correlated to the AD 472 and the Avellino (ca. 3.9 cal. ka BP) eruptions of Somma- Vesuvius. One tephra layer has benmoreitic composition and was correlated to the FL eruption of Mount Etna (ca. 3.4 cal. ka BP). The other three tephra layers have trachytic composition and were correlated to Astroni (ca. 4.2 cal. ka BP), Agnano Monte Spina (ca. 4.5 cal. ka BP) and Agnano Pomici Principali (ca. 12.3 cal. ka BP) eruptions of Campi Flegrei. The ages of tephra layers are in broad agreement with eight 14 C accelerator mass spectrometric measurements carried out on plant remains and charcoal from the lake sediments at different depths along the two cores. The recognition of distal tephra layers from Italian volcanoes allowed the physical link of the Holocene archive of Lake Shkodra to other archives located in the central Mediterranean area and the Balkans (i.e. Lake Ohrid). Five of the recognised tephra layers were recognised for the first time in the Balkans area, and this has relevance for volcanic hazard assessment and for ash dispersal forecasting in case of renewed explosive activity from some of the southern Italy volcanoes. Copyright # 2009 John Wiley & Sons, Ltd. Supporting information may be found in the online version of this article.
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- 2010
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- View/download PDF
49. Lake Ohrid, Albania, provides an exceptional multi-proxy record of environmental changes during the last glacial–interglacial cycle
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Jean-Jacques Tiercelin, Amandine Bordon, U. von Grafenstein, Soumaya Belmecheri, Eric Fouache, Cedric Robert, Christophe Grenier, P. Huntsman-Mapila, D. Hureau-Mazaudier, Z. Zeqollari, Giovanni Zanchetta, Alain Mazaud, Roberto Sulpizio, Helmut Erlenkeuser, Benoit Caron, Jean-Pierre Cazet, D. Manelli, Anne-Marie Lézine, Nils Andersen, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Glaces et Continents, Climats et Isotopes Stables (GLACCIOS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Géochrononologie Traceurs Archéométrie (GEOTRAC), Leibniz Laboratory for Radiometric Dating and Stable Isotope Research, Christian-Albrechts-University, Interactions et dynamique des environnements de surface (IDES), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Université de Pise, Laboratoire de géographie physique : Environnements Quaternaires et Actuels (LGP), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Modélisation Hydrologique (HYDRO), Harry Oppenheimer Okavango Research Centre, University of Botswana, Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS), Geological Survey, Pogradec, Climat et Magnétisme (CLIMAG), Laboratoire de Physique et Chimie de l'Environnement et de l'Espace (LPC2E), Observatoire des Sciences de l'Univers en région Centre (OSUC), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National d’Études Spatiales [Paris] (CNES), CIRISIVU Dpto Geomineralogico, Università degli studi di Bari Aldo Moro (UNIBA), Géosciences Rennes (GR), Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Dipartimento di Scienze della Terra [Pisa], University of Pisa - Università di Pisa, MAFAK - Mission archéologique franco-albanaise du bassin de Korçë (Albanie), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] ( LSCE ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Leibniz-Lab, Radiometric Dating & Stable Isotope Research Institute, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Interactions et dynamique des environnements de surface ( IDES ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Pétrologie, géochimie, minéralogie magmatiques ( PGM2 ), Institut des Sciences de la Terre de Paris ( iSTeP ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), EA 435 Géonat, Université Paris-Est Créteil Val-de-Marne - Paris 12 ( UPEC UP12 ), Laboratoire de géographie physique ( LGP ), Université Panthéon-Sorbonne ( UP1 ) -Université Paris-Est Créteil Val-de-Marne - Paris 12 ( UPEC UP12 ) -Centre National de la Recherche Scientifique ( CNRS ), Domaines Océaniques ( LDO ), Centre National de la Recherche Scientifique ( CNRS ) -Institut d'écologie et environnement-Observatoire des Sciences de l'Univers-Université de Brest ( UBO ) -Institut national des sciences de l'Univers ( INSU - CNRS ), Université européenne de Bretagne ( UEB ), Geological Survey, Laboratoire de Physique et Chimie de l'Environnement et de l'Espace ( LPC2E ), Centre National de la Recherche Scientifique ( CNRS ) -Université d'Orléans ( UO ) -Institut national des sciences de l'Univers ( INSU - CNRS ), Università degli studi di Bari, Dipartimento di Scienze della Terra, Università di Pisa, Département des sciences de la Terre, Université Paris-Sud - Paris 11 (UP11), Institut des Sciences de la Terre de Paris (iSTeP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Harry Oppenheimer Okavango Research Center, Centre européen de recherche et d'enseignement des géosciences de l'environnement (CEREGE), Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre Armoricain de Recherches en Environnement-Centre National de la Recherche Scientifique (CNRS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre Armoricain de Recherches en Environnement-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Pétrologie, géochimie, minéralogie magmatiques (PGM2), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Panthéon-Sorbonne (UP1), Domaines Océaniques (LDO), Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Observatoire des Sciences de l'Univers-Institut d'écologie et environnement-Centre National de la Recherche Scientifique (CNRS), Université européenne de Bretagne - European University of Brittany (UEB), PSL Research University (PSL)-PSL Research University (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Centre National d’Études Spatiales [Paris] (CNES), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Rennes 2 (UR2), and Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Multi-proxy approach ,010504 meteorology & atmospheric sciences ,Lake-effect snow ,[SDE.MCG]Environmental Sciences/Global Changes ,Climate change ,Palaeoenvironments ,010502 geochemistry & geophysics ,Oceanography ,Permafrost ,01 natural sciences ,Paleontology ,Paleoclimatology ,Younger Dryas ,Glacial period ,[ SDU.STU.MI ] Sciences of the Universe [physics]/Earth Sciences/Mineralogy ,Ecology, Evolution, Behavior and Systematics ,ComputingMilieux_MISCELLANEOUS ,0105 earth and related environmental sciences ,Earth-Surface Processes ,15. Life on land ,Ohrid ,13. Climate action ,[SDU]Sciences of the Universe [physics] ,[SDU.STU.CL]Sciences of the Universe [physics]/Earth Sciences/Climatology ,Interglacial ,Albania ,Last climatic cycle ,Physical geography ,Quaternary ,Geology ,[SDU.STU.MI]Sciences of the Universe [physics]/Earth Sciences/Mineralogy - Abstract
International audience; Multi-proxy analyses on core JO2004-1 recovered from Lake Ohrid (40°55.000 N, 20°40.297E, 705 m a.s.l.) provide the first environmental and climate reconstruction in a mountainous area in Southern Europe over the last 140,000 years. The response of both lacustrine and terrestrial environments to climate change has been amplified by the peculiar geomorphological and hydrological setting, with a steep altitudinal gradient in the catchment and a karstic system feeding the lake. The karstic system was active during interglacials, leading to high carbonate production in the lake, and blocked during glacials as a result of extremely cold climate conditions with permafrost in the mountains. At the Riss–Eemian transition (Termination 2) the increase in lacustrine productivity predated forest expansion by about 10,000 years. In contrast, the Late Glacial–Holocene transition (Termination 1) was characterized by the dramatic impact of the Younger Dryas, which initially prevented interglacial carbonate production and delayed its maximum until the mid-Holocene. In contrast, forest expansion was progressive, starting as early as ca. 38,000 ago. The proximity of high mountains and the probable moderating lake effect on local climate conditions promoted forest expansion, and contributed to make the surroundings of Lake Ohrid favourable to forest refugia during the last glacial, usually steppic, period. Our study of sedimentology, mineralogy, geochemistry, magnetics, palynology and isotopes illustrates the non-linear response of terrestrial and lacustrine ecosystems to similar climate events, and demonstrates the potential of Lake Ohrid as an excellent paleoclimatic archive during the Quaternary.
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- 2010
- Full Text
- View/download PDF
50. Acteurs et processus de l'inscription : chapitre IV
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Biagioli, G., Brochot, A., Candau, Jacqueline, Ginelli, Ludovic, Moisset, A., Onodi, G., Guttinger, P., Briffaud, S., Université de Pise, Centre National de la Recherche Scientifique (CNRS), Aménités et dynamiques des espaces ruraux (UR ADBX), Centre national du machinisme agricole, du génie rural, des eaux et forêts (CEMAGREF), École nationale supérieure d'architecture et du paysage de Bordeaux (ENSAP Bordeaux), UNIVERSITE D'AGRICULTURE SAINT ETIENNE DE GODOLLO HUN, Partenaires IRSTEA, Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Université Paris Nanterre (UPN), Irstea Publications, Migration, and University of Pisa - Università di Pisa
- Subjects
[SDE] Environmental Sciences ,UNESCO ,SAINT EMILION ,[SDE]Environmental Sciences - Abstract
[Departement_IRSTEA]Territoires [TR1_IRSTEA]DTAM; National audience; Bien que guidés par une procédure unique à la fois dans son déroulement et dans son format, l'analyse des circonstances et modalités de la réalisation du dossier de demande d'inscription sur la liste du Patrimoine mondial et du rôle des acteurs ou groupes d'acteurs ayant impulsé ou relayé cette demande fait apparaître une très grande disparité sur chacun des sites concernés. Ce chapitre tente de reconstituer ce processus en mettant un accent particulier sur les circonstances qui ont mené à l'idée d'inscrire, d'une part, et sur la place relative qu'ont occupée les différents groupes d'acteurs dans le processus d'inscription, d'autre part.
- Published
- 2010
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