31 results on '"Universität Bremen Postfach"'
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2. Multiproxy assessment of Holocene relative sea-level changes in the western Mediterranean: Sea-level variability and improvements in the definition of the isostatic signal
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Nick Marriner, Alessandro Fontana, Alessio Rovere, Christophe Morhange, Matteo Vacchi, Giorgio Spada, Centre européen de recherche et d'enseignement des géosciences de l'environnement (CEREGE), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Collège de France (CdF)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Center for Marine Environmental Sciences [Bremen] (MARUM), Universität Bremen, Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Collège de France (CdF (institution))-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Recherche Agronomique (INRA), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre européen de recherche et d'enseignement de géosciences de l'environnement ( CEREGE ), Centre National de la Recherche Scientifique ( CNRS ) -Institut de Recherche pour le Développement ( IRD ) -Aix Marseille Université ( AMU ) -Collège de France ( CdF ) -Institut National de la Recherche Agronomique ( INRA ) -Institut national des sciences de l'Univers ( INSU - CNRS ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), MARUM, Universität Bremen Postfach, Vacchi, Matteo, Marriner, Nick, Morhange, Christophe, SPADA, GIORGIO, Fontana, Alessandro, and Rovere, Alessio
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Mediterranean climate ,Isostasy ,010504 meteorology & atmospheric sciences ,Antarctic ice sheet ,Context (language use) ,Sea-level database ,Sea level, Isostasy, Mediterranean Sea, Holocene ,010502 geochemistry & geophysics ,01 natural sciences ,Mediterranean sea ,Isostatic adjustment ,Settore GEO/04 - Geografia Fisica e Geomorfologia ,Mediterranean Sea ,Sea level ,Holocene ,Sea-level proxy ,[SDU.STU.GM]Sciences of the Universe [physics]/Earth Sciences/Geomorphology ,14. Life underwater ,ComputingMilieux_MISCELLANEOUS ,0105 earth and related environmental sciences ,Beachrock ,[ SDU.STU.GM ] Sciences of the Universe [physics]/Earth Sciences/Geomorphology ,Earth and Planetary Sciences (all) ,Oceanography ,13. Climate action ,General Earth and Planetary Sciences ,Spatial variability ,Geology - Abstract
A review of 917 relative sea-level (RSL) data-points has resulted in the first quality-controlled database constraining the Holocene sea-level histories of the western Mediterranean Sea (Spain, France, Italy, Slovenia, Croatia, Malta and Tunisia). We reviewed and standardized the geological RSL data-points using a new multi-proxy methodology based on: (1) modern taxa assemblages in Mediterranean lagoons and marshes; (2) beachrock characteristics (cement fabric and chemistry, sedimentary structures); and (3) the modern distribution of Mediterranean fixed biological indicators. These RSL data-points were coupled with the large number of archaeological RSL indicators available for the western Mediterranean. We assessed the spatial variability of RSL histories for 22 regions and compared these with the ICE-5G (VM2) GIA model. In the western Mediterranean, RSL rose continuously for the whole Holocene with a sudden slowdown at ~ 7.5 ka BP and a further deceleration during the last ~ 4.0 ka BP, after which time observed RSL changes are mainly related to variability in isostatic adjustment. The sole exception is southern Tunisia, where data show evidence of a mid-Holocene high-stand compatible with the isostatic impacts of the melting history of the remote Antarctic ice sheet. Our results indicate that late-Holocene sea-level rise was significantly slower than the current one. First estimates of GIA contribution indicate that, at least in the northwestern sector, it accounts at least for the 25–30% of the ongoing sea-level rise recorded by Mediterranean tidal gauges. Such contribution is less constrained at lower latitudes due to the lower quality of the late Holocene index points. Future applications of spatio-temporal statistical techniques are required to better quantify the gradient of the isostatic contribution and to provide improved context for the assessment of 20th century acceleration of Mediterranean sea-level rise.
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- 2016
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3. Eukaryotic plankton diversity in the sunlit ocean
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Jean-Marc Aury, Daniele Iudicone, Hiroyuki Ogata, Stéphane Audic, Frédéric Mahé, Fabrice Not, Johan Decelle, Gabriel Gorsky, Silvia G. Acinas, Pascal Hingamp, Sarah Romac, Noan Le Bescot, Matthieu Mulot, Sébastien Colin, Eleonora Scalco, Michael E. Sieracki, Marc Picheral, Tara Oceans Coordinators, Nicolas Henry, Stephane Pesant, Micah Dunthorn, Adriana Zingone, Sabrina Speich, Margaux Carmichael, Chris Bowler, Sarah Searson, Céline Dimier, Jeroen Raes, Gipsi Lima-Mendez, Shruti Malviya, Aleš Horák, Eric Karsenti, Ramiro Logares, Olga Flegontova, Julius Lukeš, Shinichi Sunagawa, Flora Vincent, Stefanie Kandels-Lewis, Enrique Lara, Raphael Morard, Stefan Engelen, Peer Bork, Patrick Wincker, Colomban de Vargas, Raffaele Siano, Ian Probert, Jean Weissenbach, Lars Stemmann, Cédric Berney, Samuel Chaffron, Olivier Jaillon, Lionel Guidi, Julie Poulain, Lucie Bittner, Nigel Grimsley, Diversité et Interactions au sein du Plancton Océanique (DIPO), Adaptation et diversité en milieu marin (AD2M), Station biologique de Roscoff [Roscoff] (SBR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff [Roscoff] (SBR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Genoscope - Centre national de séquençage [Evry] (GENOSCOPE), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Evolution des Protistes et Ecosystèmes Pélagiques (EPEP), Institut de biologie de l'ENS Paris (IBENS), Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Génomique métabolique (UMR 8030), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Department of ecology, Universität Kaiserslautern, Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne = University of Lausanne (UNIL), Immunobiologie Cellulaire et Moléculaire des Infections Parasitaires, Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR113-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Oceanography, University of Hawai‘i [Mānoa] (UHM), Laboratoire d'océanographie de Villefranche (LOV), Observatoire océanologique de Villefranche-sur-mer (OOVM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Faculty of Informatics [Brno] (FI / MUNI), Masaryk University [Brno] (MUNI), Center for Marine Environmental Sciences [Bremen] (MARUM), Universität Bremen, Laboratoire d'Ecologie Pélagique (PELAGOS), Dynamiques des Écosystèmes Côtiers (DYNECO), Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Département Electronique, Optronique et Signal (DEOS), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Stazione Zoologica Anton Dohrn (SZN), European Molecular Biology Laboratory [Heidelberg] (EMBL), European Molecular Biology Laboratory [Grenoble] (EMBL), Biologie intégrative des organismes marins (BIOM), Observatoire océanologique de Banyuls (OOB), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Information génomique et structurale (IGS), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Kyoto University, Rega Institute - VIB Center for the Biology of Disease, Department of Microbiology and Immunology, Bioinformatics and (eco-)systems Biology Laboratory, Louvain, Belgique, Université Catholique de Louvain = Catholic University of Louvain (UCL), Laboratoire de physique des océans (LPO), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS), European Molecular Biology Laboratory, Adaptation et diversité en milieu marin (ADMM), Institut national des sciences de l'Univers (INSU - CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Technische Universität Kaiserslautern (TU Kaiserslautern), Institute of Marine Sciences / Institut de Ciències del Mar [Barcelona] (ICM), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Laboratory of Soil Biodiversity, Université de Neuchâtel (UNINE), CNRS [GDR3280], EMBL, Agency for Administration of University and Research Grants (AGAUR) [CONES 2010-0036], Veolia Environment Foundation, EBI [PRJEB402, PRJEB6610], Genoscope/CEA, Lorient Agglomeration, Illumina, UNIMIB, Electricite de France Foundation, Fondation pour la Recherche sur la Biodiversite, Tara schooner, Fund for Scientific Research - The French Ministry of Research, French Government [ANR-11-BTBR-0008, ANR-10-INBS-09-08, ANR-10-LABX-54], French Ministry of Foreign Affairs, UPMC, European Research Council [294823], VIB, Stazione Zoologica Anton Dohrn, Rega Institute, Japan Society for the Promotion of Science [26430184], KU Leuven, PSL* Research University [ANR-11-IDEX-0001-02], World Courier, ANR [POSEIDON/ANR-09-BLAN-0348, PROMETHEUS/ANR-09-PCS-GENM-217, PHYTBACK/ANR-2010-1709-01, TARA-GIRUS/ANR-09-PCS-GENM-218], EU FP7 [287589, IHMS/HEALTH-F4-2010-261376], Gordon and Betty Moore Foundation [3790], Prince Albert II de Monaco Foundation, Spanish Ministry of Science and Innovation [CGL2011-26848/BOS], Diversité et Interactions au sein du Plancton Océanique ( DIPO ), Adaptation et diversité en milieu marin ( ADMM ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), Genoscope - Centre national de séquençage [Evry] ( GENOSCOPE ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Evolution des Protistes et Ecosystèmes Pélagiques ( EPEP ), Institut de biologie de l'ENS Paris (UMR 8197/1024) ( IBENS ), École normale supérieure - Paris ( ENS Paris ) -École normale supérieure - Paris ( ENS Paris ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Génomique métabolique ( UMR 8030 ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université d'Évry-Val-d'Essonne ( UEVE ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Institut de Biologie Paris-Seine, Institute of Molecular Biology and Swiss Institute of Bioinformatics, University of Zürich [Zürich] ( UZH ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -IFR113-Institut National de la Santé et de la Recherche Médicale ( INSERM ), University of Hawaii at Manoa ( UHM ), Laboratoire d'océanographie de Villefranche ( LOV ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Faculty of Informatics [Masaryk], Masaryk University, Institut de Génomique, Genoscope, Centre National de Séquençage, MARUM, Universität Bremen Postfach, Dynamiques de l'Environnement Côtier ( DYNECO ), Institut Français de Recherche pour l'Exploitation de la Mer ( IFREMER ), Département Electronique, Optronique et Signal ( DEOS ), Institut Supérieur de l'Aéronautique et de l'Espace ( ISAE-SUPAERO ), Stazione Zoologica Napoli, European Molecular Biology Laboratory [Heidelberg] ( EMBL ), European Molecular Biology Laboratory ( EMBL ), Biologie intégrative des organismes marins ( BIOM ), Observatoire océanologique de Banyuls ( OOB ), Information génomique et structurale ( IGS ), Aix Marseille Université ( AMU ) -Centre National de la Recherche Scientifique ( CNRS ), Kyoto University [Kyoto], Université Catholique de Louvain ( UCL ), Laboratoire de physique des océans ( LPO ), Institut de Recherche pour le Développement ( IRD ) -Institut Français de Recherche pour l'Exploitation de la Mer ( IFREMER ) -Université de Brest ( UBO ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire des Sciences de l'Environnement Marin (LEMAR) ( LEMAR ), Institut de Recherche pour le Développement ( IRD ) -Institut Français de Recherche pour l'Exploitation de la Mer ( IFREMER ) -Université de Brest ( UBO ) -Institut Universitaire Européen de la Mer ( IUEM ), Institut de Recherche pour le Développement ( IRD ) -Université de Brest ( UBO ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut de Recherche pour le Développement ( IRD ) -Université de Brest ( UBO ) -Centre National de la Recherche Scientifique ( CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Technische Universität Kaiserskautern, Institute of Marine Sciences / Institut de Ciències del Mar [Barcelona] ( ICM ), Consejo Superior de Investigaciones Científicas [Spain] ( CSIC ), Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), UCL - SST/LIBST - Louvain Institute of Biomolecular Science and Technology, Institut de biologie de l'ENS Paris (UMR 8197/1024) (IBENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université d'Évry-Val-d'Essonne (UEVE), Université de Lausanne (UNIL), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Dynamiques de l'Environnement Côtier (DYNECO), Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
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Multidisciplinary ,biology ,[ SDV ] Life Sciences [q-bio] ,Ecology ,Range (biology) ,[SDV]Life Sciences [q-bio] ,fungi ,Rhizaria ,Biodiversity ,15. Life on land ,Ribosomal RNA ,Plankton ,biology.organism_classification ,[ SDE ] Environmental Sciences ,Phylogenetics ,[SDE]Environmental Sciences ,natural sciences ,14. Life underwater ,Taxonomic rank ,Ribosomal DNA - Abstract
Vargas, Colomban de ... et. al.-- 11 pages, 7 figures, supplementary materials www.sciencemag.org/content/348/6237/1261605/suppl/DC1, Marine plankton support global biological and geochemical processes. Surveys of their biodiversity have hitherto been geographically restricted and have not accounted for the full range of plankton size. We assessed eukaryotic diversity from 334 size-fractionated photic-zone plankton communities collected across tropical and temperate oceans during the circumglobal Tara Oceans expedition. We analyzed 18S ribosomal DNA sequences across the intermediate plankton-size spectrum from the smallest unicellular eukaryotes (protists, >0.8 micrometers) to small animals of a few millimeters. Eukaryotic ribosomal diversity saturated at ∼150,000 operational taxonomic units, about one-third of which could not be assigned to known eukaryotic groups. Diversity emerged at all taxonomic levels, both within the groups comprising the ∼11,200 cataloged morphospecies of eukaryotic plankton and among twice as many other deep-branching lineages of unappreciated importance in plankton ecology studies. Most eukaryotic plankton biodiversity belonged to heterotrophic protistan groups, particularly those known to be parasites or symbiotic hosts. © 2015, American Association for the Advancement of Science. All rights reserved, We thank the following people and sponsors for their commitment: CNRS (in particular, the GDR3280); EMBL; Genoscope/CEA; UPMC; VIB; Stazione Zoologica Anton Dohrn; UNIMIB; Rega Institute; KU Leuven; Fund for Scientific Research – The French Ministry of Research, the French Government “Investissements d’Avenir” programmes OCEANOMICS (ANR-11-BTBR-0008), FRANCE GENOMIQUE (ANR-10-INBS-09-08), and MEMO LIFE (ANR-10-LABX-54); PSL* Research University (ANR-11-IDEX-0001-02); ANR (projects POSEIDON/ANR-09-BLAN-0348, PROMETHEUS/ANR-09-PCSGENM-217, PHYTBACK/ANR-2010-1709-01, and TARA-GIRUS/ANR-09-PCS-GENM-218); EU FP7 (MicroB3/No.287589, IHMS/HEALTH-F4-2010-261376); European Research Council Advanced Grant Awards to C. Bowler (Diatomite:294823); Gordon and Betty Moore Foundation grant 3790 to M.B.S.; Spanish Ministry of Science and Innovation grant CGL2011-26848/BOS MicroOcean PANGENOMICS and TANIT (CONES 2010-0036) grant from the Agency for Administration of University and Research Grants (AGAUR) to S.G.A.; and Japan Society for the Promotion of Science KAKENHI grant 26430184 to H.O. We also thank the following for their support and commitment: A. Bourgois, E. Bourgois, R. Troublé, Région Bretagne, G. Ricono, the Veolia Environment Foundation, Lorient Agglomération, World Courier, Illumina, the Electricité de France Foundation, Fondation pour la Recherche sur la Biodiversité, the Prince Albert II de Monaco Foundation, and the Tara schooner and its captains and crew. We thank MERCATORCORIOLIS and ACRI-ST for providing daily satellite data during the expedition. We are also grateful to the French Ministry of Foreign Affairs for supporting the expedition and to the countries who granted sampling permissions. Tara Oceans would not exist without continuous support from 23 institutes (http://oceans.taraexpeditions.org)
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- 2015
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4. Predictability of biomass burning in response to climate changes
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T I Harrison-Prentice, Janelle Stevenson, Sandy P. Harrison, Colin J. Long, Jennifer R. Marlon, Hermann Behling, Lydie M Dupont, Scott Mooney, Douglas J. Hallett, Elin Norström, Christopher Carcaillet, Fumitaka Katamura, Natasha L. Williams, K. J. Brown, Frank H. Neumann, Hikaru Takahara, John Dodson, Sergey K. Krivonogov, Patrick J. Bartlein, Willy Tinner, C. Paitre, Florian Thevenon, G.M. Mckenzie, Donna D'Costa, M.P. Black, Aurélie Genries, Patricio I. Moreno, Iain Colin Prentice, Mitchell J. Power, Zewdu Eshetu, Geoffrey Hope, Patrick Moss, Lisa M. Kennedy, Elena Marinova, Simon Haberle, Megan K. Walsh, T.G. Kassa, Verushka Valsecchi, Sally P. Horn, Pierre Friedlingstein, Neil Roberts, Louis Scott, Valery T. Terwilliger, Daniel G. Gavin, Eric A. Colhoun, Rebecca Turner, Kenji Izumi, Peter Kershaw, Juliana Atanassova, Guy Robinson, Basil A. S. Davis, Maja Andrič, Yunlin Zhang, Donatella Magri, Naoko Sasaki, Anne-Laure Daniau, Olivier Blarquez, Scott Brewer, Damien Rius, Jun Inoue, Boris Vannière, Daniele Colombaroli, School of Geographical Sciences, University of Bristol [Bristol], Department of Geography, University of Oregon [Eugene], School of Biological Sciences, Macquarie University, School of Earth Sciences [Bristol], Grantham Institute for Climate Change and Division of Biology, Imperial College London, Botany Department, University of Wyoming ( UW ), College of Engineering, Mathematics and Physical Sciences [Exeter] ( EMPS ), University of Exeter, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] ( LSCE ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Newton St. Cyres, Osaka University [Osaka], University of Wisconsin-Madison [Madison], School of Biological, Earth and Environmental Sciences ( UNSW - BEES ), University of New South Wales [Sydney] ( UNSW ), Utah Museum of Natural History, Department of Geography, University of Utah, University of Utah, Department of Archaeology and Natural History, Australian National University ( ANU ), Oeschger Centre for Climate Change Research ( OCCR ), University of Bern, Institute of Archaeology, Scientific Research Centre of the Slovenian Academy of Sciences and Arts, Department of Botany, Sofia University 'Sv. Kliment Ohridski', Palynology and Climate Dynamics, Albrecht-von-Haller-Inst. for Plant Sciences, Centre de Bio-Archéologie et d'Ecologie ( CBAE ), Université Montpellier 2 - Sciences et Techniques ( UM2 ) -École pratique des hautes études ( EPHE ) -Centre National de la Recherche Scientifique ( CNRS ), Canadian Forest Service, Victoria, British Columbia, Paléoenvironnement et chronoécologie UMR 5059-CNRS/Montpellier II/EPHE ( PALECO ), École pratique des hautes études ( EPHE ), School of Environmental and Life Sciences, The University of Newcastle, Institute of Environment, Science and Technology, Ecole Polytechnique Fédérale de Lausanne ( EPFL ), School of Geography and Environmental Science, Monash University [Clayton], Institute for Environmental Research, Australian Nuclear Science and Technology Organisation, MARUM, Universität Bremen Postfach, Department of Paleoanthropology and Paleoenvironment, University of Addis Ababa, Department of Archaeology and Natural History ( RSPS ), Biogeoscience Institute, University of Calgary, The University of Tennessee [Knoxville], Seminar of Geography and Education, University of Cologne, Tokushu Kosho Gijutsu Inc, Virginia Polytechnic and State University, United Institute of Geology, Geophysics and Mineralogy of the Russian Academy of Sciences, Siberian Branch of the Russian Academy of Sciences ( SB RAS ), Department of Geography and Urban Planning, Dipartimento di Biologia Vegetale, Università degli Studi di Roma 'La Sapienza' [Rome], Institute of Ecology and Biodiversity and Department of Ecological Sciences, Facultad de Ciencias, Universidad de Chile, Department of Planning and Environmental Management, School of Geography, The University of Queensland, Bernard Price Institute for Palaeontology, University of the Witwatersrand [Johannesburg] ( WITS ), Forschungsstelle für Paläobotanik, Westfälische Wilhelms-Universität Münster ( WWU ), Department of Physical Geography and Quaternary Geology, Stockholm University, Département de Géographie et Centre d'Études Nordiques, Université Laval, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre National de la Recherche Scientifique ( CNRS ), Earth and Environmental Sciences, School of Geography, University of Plymouth, Department of Natural Sciences, Fordham College at Lincoln Center, Research Institute for Humanity and Nature, Department of Plant Sciences, University of the Free State [South Africa], Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Institut des Sciences de la Terre d'Orléans - UMR7327 ( ISTO ), Bureau de Recherches Géologiques et Minières (BRGM) ( BRGM ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Université d'Orléans ( UO ) -Centre National de la Recherche Scientifique ( CNRS ), University of Kansas [Lawrence] ( KU ), Forel Institute, University of Geneva [Switzerland], Pedagogic Research Institute and Observatory, University of Plymouth, Central Washington University, Natural Resources Policy Section, NSW Department of Premier and Cabinet, Institute of Botany, State Key Laboratory of Vegetation and Environmental Change, Chinese Academy of Sciences [Beijing] ( CAS ), School of Geographical Sciences [Bristol], University of Wyoming (UW), College of Engineering, Mathematics and Physical Sciences [Exeter] (EMPS), Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), University of Wisconsin-Madison, School of Biological, Earth and Environmental Sciences [Sydney] (BEES), University of New South Wales [Sydney] (UNSW), Australian National University (ANU), Oeschger Centre for Climate Change Research (OCCR), Sofia University 'St. Kliment Ohridski', Centre de Bio-Archéologie et d'Ecologie (CBAE), Université Montpellier 2 - Sciences et Techniques (UM2)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Paléoenvironnement et chronoécologie UMR 5059-CNRS/Montpellier II/EPHE (PALECO), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Ecole Polytechnique Fédérale de Lausanne (EPFL), Center for Marine Environmental Sciences [Bremen] (MARUM), Universität Bremen, Addis Ababa University (AAU), Department of Archaeology and Natural History (RSPS), Siberian Branch of the Russian Academy of Sciences (SB RAS), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), University of the Witwatersrand [Johannesburg] (WITS), Westfälische Wilhelms-Universität Münster = University of Münster (WWU), Université Laval [Québec] (ULaval), Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), School of Geography, Earth and Environmental Sciences [Plymouth] (SoGEES), Plymouth University, Fordham University [New York], Research Institute for Humanity and Nature (RIHN), University of the Free State [South Africa] (UFS), Kyoto Prefectural University (KPU), Institut des Sciences de la Terre d'Orléans - UMR7327 (ISTO), Bureau de Recherches Géologiques et Minières (BRGM) (BRGM)-Observatoire des Sciences de l'Univers en région Centre (OSUC), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS), University of Kansas [Lawrence] (KU), Université de Genève = University of Geneva (UNIGE), Chinese Academy of Sciences [Beijing] (CAS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Centre National de la Recherche Scientifique (CNRS)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Montpellier 2 - Sciences et Techniques (UM2), École pratique des hautes études (EPHE), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Westfälische Wilhelms-Universität Münster (WWU), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers en région Centre (OSUC), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Bureau de Recherches Géologiques et Minières (BRGM) (BRGM)
- Subjects
biomass burning ,010506 paleontology ,Atmospheric Science ,010504 meteorology & atmospheric sciences ,temperature changes ,[SDE.MCG]Environmental Sciences/Global Changes ,Climate change ,deglaciation ,01 natural sciences ,sedimentary charcoal records ,ddc:550 ,[ SDU.ENVI ] Sciences of the Universe [physics]/Continental interfaces, environment ,Environmental Chemistry ,Predictability ,[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces, environment ,Biomass burning ,0105 earth and related environmental sciences ,General Environmental Science ,Global and Planetary Change ,Fire regime ,Moisture ,Holocene ,Global warming ,15. Life on land ,Sedimentary charcoal ,[ SDE.MCG ] Environmental Sciences/Global Changes ,[SDU.STU.CL]Sciences of the Universe [physics]/Earth Sciences/Climatology ,13. Climate action ,Climatology ,Environmental science ,[ SDU.STU.CL ] Sciences of the Universe [physics]/Earth Sciences/Climatology ,climate controls on fire ,holocene - Abstract
Climate is an important control on biomass burning, but the sensitivity of fire to changes in temperature and moisture balance has not been quantified. We analyze sedimentary charcoal records to show that the changes in fire regime over the past 21,000 yrs are predictable from changes in regional climates. Analyses of paleo- fire data show that fire increases monotonically with changes in temperature and peaks at intermediate moisture levels, and that temperature is quantitatively the most important driver of changes in biomass burning over the past 21,000 yrs. Given that a similar relationship between climate drivers and fire emerges from analyses of the interannual variability in biomass burning shown by remote-sensing observations of month-by-month burnt area between 1996 and 2008, our results signal a serious cause for concern in the face of continuing global warming. ispartof: Global Biogeochemical Cycles vol:26 issue:4 status: published
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5. [On the need for financial and structural reform of long-term care insurance].
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Rothgang H
- Subjects
- Humans, Germany, Income, Long-Term Care, Health Care Reform, Insurance, Long-Term Care, Insurance, Health
- Abstract
When long-term care insurance was introduced in 1994, a number of conceptual decisions were made that continue to shape the system today. This discussion article examines three of these decisions. In each case, an evaluation standard is formulated against which the current situation is assessed. In the case of a negative assessment, reform options are discussed.In combination with the lack of benefit adjustments, the design of long-term care insurance as a system with capped insurance benefits and unlimited co-payments has led to co-payment levels in nursing homes that the majority of residents cannot cover from their income. Therefore, in order to fulfill its original objectives, long-term care insurance would have be turned upside down - by imposing an absolute limit on the amount and duration of the individual co-payments.The "dual insurance system" consisting of a social insurance for the majority and a private mandatory plan for a minority of the population has also proved to be a "birth defect" of the system. Since the group of privately insured persons has a much more favorable risk structure and higher average incomes, the "equal distribution of burdens" in financing required by the Federal Constitutional Court does not exist. To remedy this inequality, the dual system must be transformed into an integrated long-term care insurance system, or at least a risk structure equalization scheme between the two branches must be implemented.The introduction of long-term care insurance as a separate branch of social insurance, however, can be justified. In order to overcome interface problems, it would nevertheless be necessary to place the financing competence for geriatric rehabilitation with long-term care insurance and that for medical treatment care in nursing homes with health insurance., (© 2023. The Author(s).)
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- 2023
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6. Impfstoffe gegen SARS-CoV-2: Zulassungskriterien, Aufklärungsvoraussetzungen und Auswahlmöglichkeiten.
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Hart D
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- 2021
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7. The strong arm of the law: a unified account of necessary and contingent laws of nature.
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Hirèche S, Linnemann N, Michels R, and Vogt L
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A common feature of all standard theories of the laws of nature is that they are 'absolutist': They take laws to be either all metaphysically necessary or all contingent. Science, however, gives us reason to think that there are laws of both kinds, suggesting that standard theories should make way for 'non-absolutist' alternatives: theories which accommodate laws of both modal statuses. In this paper, we set out three explanatory challenges for any candidate non-absolutist theory, and discuss the prospects of the two extant candidates in light of these challenges. We then develop our own non-absolutist theory, the essentialist DTA account, which combines the nomic-necessitation or DTA account with an essentialist approach to metaphysical modality in order to meet the three explanatory challenges. Finally, we argue that the distinction between kinematical and dynamical laws found in physical theories supports both non-absolutism in general and our proposed essentialist DTA view in particular., Competing Interests: Conflicts of interest/Competing interestsNo conflicts of interest., (© The Author(s) 2021.)
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- 2021
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8. Zur Konkurrenz der Impfstoffe gegen COVID-19: Aufklärung und Auswahl.
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Hart D
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- 2021
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9. [Special topic "Family care matters: at what cost?"]
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Frewer-Graumann S, Heß M, and Aner K
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- Humans, Family Health economics
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- 2020
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10. Striped pattern selection by advective reaction-diffusion systems: resilience of banded vegetation on slopes.
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Siero E, Doelman A, Eppinga MB, Rademacher JD, Rietkerk M, and Siteur K
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- Diffusion, Computer Simulation, Ecosystem, Models, Biological, Nonlinear Dynamics, Plant Development physiology, Water metabolism
- Abstract
For water-limited arid ecosystems, where water distribution and infiltration play a vital role, various models have been set up to explain vegetation patterning. On sloped terrains, vegetation aligned in bands has been observed ubiquitously. In this paper, we consider the appearance, stability, and bifurcations of 2D striped or banded patterns in an arid ecosystem model. We numerically show that the resilience of the vegetation bands is larger on steeper slopes by computing the stability regions (Busse balloons) of striped patterns with respect to 1D and transverse 2D perturbations. This is corroborated by numerical simulations with a slowly decreasing water input parameter. Here, long wavelength striped patterns are unstable against transverse perturbations, which we also rigorously prove on flat ground through an Evans function approach. In addition, we prove a "Squire theorem" for a class of two-component reaction-advection-diffusion systems that includes our model, showing that the onset of pattern formation in 2D is due to 1D instabilities in the direction of advection, which naturally leads to striped patterns.
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- 2015
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11. [Sex-specific differences in drug utilisation in different phases of life].
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Hoffmann F, Bachmann CJ, Boeschen D, Glaeske G, Schulze J, Schmiemann G, and Windt R
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- Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Cohort Studies, Female, Germany epidemiology, Humans, Male, Middle Aged, Sex Distribution, Young Adult, Drug Prescriptions statistics & numerical data, Drug Utilization Review, Health Care Rationing statistics & numerical data, Practice Patterns, Physicians' statistics & numerical data, Sexism statistics & numerical data
- Abstract
The aim of the present study is to analyse sex-specific differences in drug utilisation during different phases of life using relevant diseases as examples. We used a cohort of 1.7 million subjects who were insured with the Gmünder ErsatzKasse (GEK), a German health insurance fund, for at least one day in all four quarters of 2009. We analysed subjects with outpatient diagnoses of the following diseases: attention-deficit/hyperactivity disorder (ADHD) (0-17 years), hypothyroidism (18-49 years), osteoporosis (50-79 years) and coronary heart disease (80 + years). Analysis was performed on an active-substance level. A number of differences were observed in drug treatment for the selected diseases (for example, substances for ADHD were prescribed more often in males and for hypothyroidism more often in females), as well as in prescribing practices relating to other drugs used in these groups. However, clear explanations for these differences, such as drug approval status, were not always apparent.
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- 2014
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12. [Prescription of high-potency opioids in 2011].
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Hoffmann F, Glaeske G, and Windt R
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- Administration, Cutaneous, Analgesics, Opioid adverse effects, Drug Therapy, Combination, Drug Utilization statistics & numerical data, Fentanyl adverse effects, Germany, Humans, Hydromorphone administration & dosage, Hydromorphone adverse effects, Morphine administration & dosage, Morphine adverse effects, Oxycodone administration & dosage, Oxycodone adverse effects, Analgesics, Opioid administration & dosage, Fentanyl administration & dosage, Practice Patterns, Physicians' statistics & numerical data
- Abstract
Background: The aim of this study was to analyze the prescription of high-potency (WHO step III) opioids with respect to regional differences and to assess the proportion of opioid-naïve new users of transdermal fentanyl., Methods: Prescription claims data of the largest single German health fund (BARMER GEK) with 9.1 million insured persons from the year 2011 were used. For new users of transdermal fentanyl who had had no prescription in the preceding 6 months it was studied whether they had received other high-potency or low-potency opioids before., Results: A total of 18.9 million defined daily doses (DDD) of high-potency opioids were included corresponding to a mean of 208.6 DDD per 100 persons. Significant regional differences were found with lower values in the south, ranging from 145.9 DDD in Baden-Württemberg to 259.5 DDD per 100 persons in Lower Saxony. Fentanyl was the most frequently used step III opioid (40.8% of DDDs) which is nearly only given transdermally. Of the 11,184 patients with new use of transdermal fentanyl 80.7% had received no other high-potency opioid before and 52.9% had received neither low-potency nor high-potency opioids before. The first prescription exceeded the smallest available dose of 12.5 μg/h for over half of the patients starting treatment., Conclusions: Although oral morphine, oxycodone and hydromorphone are recommended as first-line step III opioids, transdermal fentanyl seems to be prescribed too often as the first choice and might not be appropriate.
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- 2012
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13. [Urology needs health services research: the case of small renal tumours].
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Hoffmann F and Huber J
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- Evidence-Based Medicine trends, Forecasting, Germany, Humans, Kidney Neoplasms diagnosis, Kidney Neoplasms pathology, Neoplasm Staging, Nephrectomy methods, Practice Guidelines as Topic, Quality Improvement trends, Randomized Controlled Trials as Topic, Registries, Treatment Outcome, Tumor Burden, Health Services Needs and Demand trends, Health Services Research trends, Kidney Neoplasms surgery, National Health Programs trends, Urology trends
- Abstract
The central tasks of health services research include the description and analysis of health care under everyday conditions as well as the development and evaluation of new concepts. As a first step, the reality of the health services' situation should be assessed using representative data. For that, registries, claims data of health insurance funds or observational studies are suitable. To investigate specific patterns or decisions, qualitative methods are of importance. To evaluate the effectiveness of health care concepts or structures, pragmatic randomized, controlled trials are considered to provide the best evidence. In this paper we discuss these questions on the basis of treatment for patients with small renal masses. Although recent guidelines recommend nephron-sparing surgery instead of radical nephrectomy for these patients, international studies suggest that there is a significant underuse of nephron-sparing procedures. However, national data describing the situation in Germany are necessary to analyse reasons and to develop new concepts which subsequently have to be tested in randomized trials. Therefore, the aim of health services research is to create a scientific basis for continuous improvements in health care. Urology needs health services research and we should find ways to overcome barriers to improve quality of care.
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- 2011
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14. Polynuclear titanocene complexes with antimony ligands: [(Cp2Ti)2(SbR2)2] (R=Et), [(Cp2Ti)3(SbR)3Sb] [R=2-(Me2NCH2)C6H4] and [(Cp2Ti)5(SbR)2Sb7] (R=Me3SiCH2).
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Breunig HJ, Lork E, Moldovan O, Raţ CI, Rosenthal U, and Silvestru C
- Abstract
The formation and crystal structure of [(Cp2Ti)2(SbR2)2] (1, R=Et), [(Cp2Ti)3(SbR)3Sb] [2, R=2-(Me2NCH2)C6H4], and [(Cp2Ti)5(SbR)2Sb7] (3, R=Me3SiCH2) is reported.
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- 2009
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15. Goos-Hänchen shift and localization of optical modes in deformed microcavities.
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Unterhinninghofen J, Wiersig J, and Hentschel M
- Abstract
Recently, an interesting phenomenon of spatial localization of optical modes along periodic ray trajectories near avoided resonance crossings has been observed [Wiersig, Phys. Rev. Lett. 97, 253901 (2006)]. For the case of a microdisk cavity with elliptical cross section, we use the Husimi function to analyze this localization in phase space. Moreover, we present a semiclassical explanation of this phenomenon in terms of the Goos-Hänchen shift, which works very well even deep in the wave regime. This semiclassical correction to the ray dynamics modifies the phase-space structure such that modes can localize either on stable islands or along unstable periodic ray trajectories.
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- 2008
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16. Reciprocal transmissions and asymmetric modal distributions in waveguide-coupled spiral-shaped microdisk resonators: comment.
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Wiersig J
- Subjects
- Computer Simulation, Equipment Design, Equipment Failure Analysis, Computer-Aided Design, Models, Theoretical, Optics and Photonics instrumentation, Telecommunications instrumentation, Transducers
- Abstract
In a recent article [Opt. Express 15, 14650 (2007)] Lee et al. claimed that optical modes in spiral-shaped microcavities come in pairs of clockwise and counterclockwise traveling-wave modes having the same frequencies and Q-factors but different modal distributions. In this comment, we show that the opposite is true: the modes are in general nondegenerate in terms of frequencies and Q-factors and the modal distributions are similar.
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- 2008
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17. UHV studies of methanol decomposition on mono- and bimetallic CoPd nanoparticles supported on thin alumina films.
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Nowitzki T, Borchert H, Jürgens B, Risse T, Zielasek V, and Bäumer M
- Abstract
Bimetallic nanoparticles often turn out to be superior to the corresponding monometallic systems with respect to their catalytic properties. To study such effects for the methanol decomposition reaction, model catalysts were prepared by physical vapor deposition of Pd and Co under ultrahigh-vacuum (UHV) conditions. Monometallic Pd and Co particles as well as CoPd core-shell particles were generated on an epitaxial alumina film grown on NiAl(110). The interaction with methanol is examined by temperature-programmed desorption of methanol and carbon monoxide and by X-ray photoelectron spectroscopy. The decomposition of methanol proceeds in two reaction pathways independent of the particle composition: complete dehydrogenation towards carbon monoxide and hydrogen, and C--O bond scission yielding carbon deposits. Pd is the most active material studied here. The relative importance of the two channels varies for the different particle systems: on Pd dehydrogenation is preferred, whereas the C--O bond cleavage is more pronounced on Co. The bimetallic clusters show a moderate performance for both pathways. Carbon deposition poisons the model catalysts by blocking the adsorption sites for methoxide, which is the first intermediate product during methanol decomposition. In particular on Co, large amounts of carbon deposits can also be caused by dissociation of the final product of the dehydrogenation pathway, carbon monoxide. A comparison with the results of methanol decomposition on Co, Pd, and CoPd catalysts in continuous-flow reactors demonstrates that the findings of the present UHV study are relevant for catalytic performance under high-pressure conditions.
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- 2008
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18. Formation of long-lived, scarlike modes near avoided resonance crossings in optical microcavities.
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Wiersig J
- Abstract
We study the formation of long-lived states near avoided resonance crossings in open systems. For three different optical microcavities (rectangle, ellipse, and semistadium) we provide numerical evidence that these states are localized along periodic rays, resembling scarred states in closed systems. Our results shed light on the morphology of long-lived states in open mesoscopic systems.
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- 2006
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19. Perlwapin, an abalone nacre protein with three four-disulfide core (whey acidic protein) domains, inhibits the growth of calcium carbonate crystals.
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Treccani L, Mann K, Heinemann F, and Fritz M
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- Amino Acid Sequence, Animals, Crystallization, Microscopy, Atomic Force, Molecular Sequence Data, Protein Structure, Tertiary, Calcium Carbonate chemistry, Disulfides chemistry, Proteins chemistry, Snails chemistry
- Abstract
We have isolated a new protein from the nacreous layer of the shell of the sea snail Haliotis laevigata (abalone). Amino acid sequence analysis showed the protein to consist of 134 amino acids and to contain three sequence repeats of approximately 40 amino acids which were very similar to the well-known whey acidic protein domains of other proteins. The new protein was therefore named perlwapin. In addition to the major sequence, we identified several minor variants. Atomic force microscopy was used to explore the interaction of perlwapin with calcite crystals. Monomolecular layers of calcite crystals dissolve very slowly in deionized water and recrystallize in supersaturated calcium carbonate solution. When perlwapin was dissolved in the supersaturated calcium carbonate solution, growth of the crystal was inhibited immediately. Perlwapin molecules bound tightly to distinct step edges, preventing the crystal layers from growing. Using lower concentrations of perlwapin in a saturated calcium carbonate solution, we could distinguish native, active perlwapin molecules from denaturated ones. These observations showed that perlwapin can act as a growth inhibitor for calcium carbonate crystals in saturated calcium carbonate solution. The function of perlwapin in nacre growth may be to inhibit the growth of certain crystallographic planes in the mineral phase of the polymer/mineral composite nacre.
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- 2006
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20. Principal and independent components analysis of overlapping spectra in the context of multichannel time-resolved absorption spectroscopy.
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Gómez Martín JC, Spietz P, Orphal J, and Burrows JP
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- Kinetics, Models, Chemical, Principal Component Analysis, Spectrum Analysis, Time Factors, Chemistry Techniques, Analytical, Iodine chemistry, Ozone chemistry
- Abstract
The separation of overlapping absorption spectra in the context of multichannel time-resolved absorption spectroscopy and chemical kinetics is a particular case in the general problem of splitting the observed data into several linear components. Here, principal and independent components analysis are applied to kinetic data of iodine--ozone chemistry, which contains overlapping spectra of different absorbers. The objective of this work is to demonstrate a method which in spite of this overlap is able to extract separated time traces of such absorbers. These time traces are clearly a pre-requisite for any further accurate quantitative analysis. The statistical properties of data recordings obtained from flash photolysis of I(2) and O(3) have been studied to check if the requirements of the model are fulfilled. Results of separation in appropriate spectral windows displaying overlapped vibrational features are presented. Validation is made using prior information and conventional techniques.
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- 2004
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21. Anionic triazine systems.
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Kingston M, Chen SJ, Lork E, and Mews R
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The synthesis of TAS+ C3N3F4- (1) (TAS+ = (Me2N)3S+) and the reactions of 1 with Me3SiOSiMe3 and Me3SiCF3 to give TAS+ C3N3F2O- (2) and TAS+[(NCF)(NCCF3)(NC(CF3)(2)]- (4) are reported. An isomer of 4, TAS+[(NCCF3)2(NCFCF3)]-, compound 6, was obtained by fluoride ion addition to (CF3CN)3. From the reactions with Me3SiNMe2 neutral fluoroamino triazines C3N3Fn(NMe2)(n-1) (n = 1, 2) were isolated. Possible reaction pathways are discussed, the X-ray structures of 1, 2, 4 and 6 were determined.
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- 2004
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22. The nacre protein perlucin nucleates growth of calcium carbonate crystals.
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Blank S, Arnoldi M, Khoshnavaz S, Treccani L, Kuntz M, Mann K, Grathwohl G, and Fritz M
- Subjects
- Crystallization, Microscopy, Atomic Force, Microscopy, Electron, Scanning, Calcium Carbonate chemistry, Lectins chemistry
- Abstract
Atomic force microscopy (AFM) in aqueous solution was used to investigate native nacre of the marine snail Haliotis laevigata on the microscopic scale and the interaction of purified nacre proteins with calcium carbonate crystals on the nanoscopic scale. These investigations were controlled by scanning electron microscopy (SEM), light microscopy (LM) and biochemical methods. For investigations with AFM and SEM, nacre was cleaved parallel to the aragonite tablets in this biogenic polymer/mineral composite. Multilamellar organic sheets consisting of a core of chitin with layers of proteins attached on both sides lay between the aragonite layers consisting of confluent aragonite tablets. Cleavage appeared to occur between the aragonite tablet layer and the protein layer. AFM images revealed a honeycomb-like structure to the organic material with a diameter of the 'honeycombs' equalling that of the aragonite tablets. The walls of the structures consisted of filaments, which were suggested to be collagen. The flat regions of the honeycomb-like structures exhibited a hole with a diameter of more than 100 nm. When incubated in saturated calcium carbonate solution, aragonite needles with perfect vertical orientation grew on the proteinacous surface. After treatment with proteinase K, no growth of orientated aragonite needles was detected. Direct AFM measurements on dissolving and growing calcite crystals revealed a surface structure with straight steps the number of which decreased with crystal growth. When the purified nacre protein perlucin was added to the growth solution (a super-saturated calcium carbonate solution) new layers were nucleated and the number of steps increased. Anion exchange chromatography of the water-soluble proteins revealed a mixture of about 10 different proteins. When this mixture was dialysed against saturated calcium carbonate solution and sodium chloride, calcium carbonate crystals precipitated together with perlucin leaving the other proteins in the supernatant. Thus perlucin was shown to be a protein able to nucleate calcium carbonate layers on calcite surfaces, and in the presence of sodium chloride, is incorporated as an intracrystalline protein into calcium carbonate crystals.
- Published
- 2003
- Full Text
- View/download PDF
23. [Oxidative stress, age-dependent [correction of age-related] cell damage and antioxidative mechanisms].
- Author
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Gosslau A and Rensing L
- Subjects
- Aged, Humans, Lipid Peroxidation physiology, Mitochondria physiology, Antioxidants metabolism, Cellular Senescence physiology, DNA Damage physiology, Glutathione Peroxidase physiology, Oxidative Stress physiology
- Abstract
Cellular oxidative stress is due to the production of reactive oxygen species (ROS), on the one hand, and weaknesses of the antioxidative defence, on the other. This is particularly true for cells with an active metabolism such as neurons and muscle cells, but it is also relevant for all other cell types. Hydrogen peroxide is an important member of ROS and is generated predominantly by mitochondria. In combination with reduced trace metals such as iron or copper, hydrogen peroxide is transformed into the highly reactive hydroxyl radical which causes damage to virtually all macromolecules. Oxidation of nucleic acids results in mutations while protein denaturation leads to enzyme defects and impairment of the cytoskeleton. Lipid peroxidation in cell membranes is strongly involved in the perturbation of ion homeostasis. Because this cell damage ultimatively causes cell death, oxidative stress initiates several diseases. Mitochondria play a major role in this context because they are the main source of endogenous oxidative stress and additionally function as an inducer of programmed cell death (apoptosis). Several strategies of antioxidative defence exist: While transition metals can be inactivated by chelating proteins (e.g., ferritin), ROS can be reduced enzymatically (e.g., by the glutathione peroxidase) or non-enzymatically by antioxidants (e.g., by vitamin E, vitamin C and glutathione). Stress proteins are implicated in the repair and transport of denatured proteins as well as in the inhibition of apoptosis.
- Published
- 2002
- Full Text
- View/download PDF
24. [On the stressful state of affairs between and social and confinement rights. Do confinement rights belong to medicine more than to social laws?].
- Author
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Francke R and Hart D
- Subjects
- Germany, Humans, Quality Assurance, Health Care, Social Medicine standards, Social Responsibility
- Published
- 2001
25. [Attending physician between therapeutic freedom and practice guidelines].
- Author
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Hart D
- Subjects
- Evidence-Based Medicine trends, Germany, Humans, Insurance Coverage legislation & jurisprudence, Insurance Coverage standards, Legislation, Medical, Practice Guidelines as Topic, Professional Autonomy, Clinical Competence standards, Guideline Adherence, Insurance Coverage trends
- Published
- 2001
- Full Text
- View/download PDF
26. Tris(azolyl)methylthiolates: Another New Scorpionate Class?
- Author
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Müller M, Lork E, and Mews R
- Published
- 2001
27. Chromosome aberration analysis in Concorde pilots.
- Author
-
Heimers A
- Subjects
- Adult, Dose-Response Relationship, Radiation, Humans, Lymphocytes cytology, Lymphocytes metabolism, Lymphocytes radiation effects, Male, Micronuclei, Chromosome-Defective radiation effects, Middle Aged, Occupational Diseases etiology, Occupational Exposure adverse effects, Radiation, Sister Chromatid Exchange radiation effects, Translocation, Genetic radiation effects, Aircraft, Chromosome Aberrations, Occupational Diseases genetics
- Abstract
Chromosomal aberrations, micronuclei, and sister chromatid exchanges have been analysed in human peripheral lymphocytes of 18 Concorde pilots and 10 controls. There was an eightfold significant increase of dicentric chromosomes in the Concorde group. The yield of micronuclei was also significantly elevated. Sister chromatid exchanges in the Concorde group did not differ from the control. Comparing the results to flight personnel from subsonic routes, the dicentric yield was higher in personnel from supersonic crews but the difference was not statistically significant. The overdispersion of dicentric chromosomes showed the influence of high LET cosmic radiation. The estimated mean dose per year ranged from 11 to 37 mSv depending on the radiation weighting factor for neutrons. It is recommended that actual and future high-speed transport should consider not only physical measurements, but also biological data like the frequencies of chromosomal aberrations because the latter reflect sensitively the high biological effectiveness of cosmic radiation.
- Published
- 2000
- Full Text
- View/download PDF
28. Structural chemistry of bismuth compounds. I. Organobismuth derivatives.
- Author
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Silvestru C, Breunig HJ, and Althaus H
- Published
- 1999
- Full Text
- View/download PDF
29. Analysis of metal-induced oxidative DNA damage in cultured mammalian cells.
- Author
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Hartwig A, Schlepegrell R, and Beyersmann D
- Abstract
Reactive oxygen species are continuously generated during oxygen metabolism, and a measurable amount of oxidative DNA damage exists in aerobic organisms. By the determination of Fpg-sensitive sites in mammalian cells in culture, we assessed the background level of oxidative DNA damage and its potential increase by extracellularly applied complexes of iron(III). In V79 Chinese hamster cells the endogenous level of Fpg-sensitive modifications is detectable, but the extent is much lower as compared with results derived from other analytical methods. In V79 cells, the frequency of Fpg-sensitive modifications is considerably enhanced by Fe-NTA in a time- and dose-dependent manner, while no increase is observed after treatment with Fe-citrate. These results indicate that the ability of transition metals to generate oxidative DNA damage in intact cells strongly depends on factors like uptake and intracellular distribution, which will affect the intracellular availability of redox-active metal ions close to critical targets.
- Published
- 1996
- Full Text
- View/download PDF
30. In situ nuclear magnetic resonance of N pulse labels monitors different routes for nitrogen assimilation.
- Author
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Callies R, Altenburger R, Abarzua S, Mayer A, Grimme LH, and Leibfritz D
- Abstract
Nuclear magnetic resonance offers the possibility of noninvasive in situ observation of (15)N pulse labeling in the presence of light. In vivo, exclusively the delta-nitrogen of Gln is labeled in the cyanobacterium Microcystis firma when glutamate synthase is inhibited by azaserine. In contrast, the green alga Chlorella fusca is additionally capable of incorporating nitrogen into Glu, thus providing evidence for an anabolic function of glutamate dehydrogenase in this organism.
- Published
- 1992
- Full Text
- View/download PDF
31. pH-preferences and habitat selection in carabid beetles.
- Author
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Paje F and Mossakowski D
- Abstract
Seven species of carabid beetles were examined in different "pH-Orgeln" for pH-preferences. Five of these species showed significant preferences for specific pH-fields. Presumably, this parameter of distribution found in the laboratory is also effective in the field. We caught the beetles in the field on soil of the same pH-values which they prefered in the laboratory. The pH-measurements taken by previous workers in the field match our results.The receptors for H-ions are probably located on the antennae, because the preference distribution of Pt. angustatus changed into a uniform distribution after amputation of the distal segments of the antennae. The structure of these receptors could not be identified in electron microscope pictures (REM) among the multitude of different receptors on the antennae.
- Published
- 1984
- Full Text
- View/download PDF
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